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https://www.readbyqxmd.com/read/28823144/factors-impacting-patient-cooperation-during-elective-gastroscopy
#1
Sang Pyo Lee, In-Kyung Sung, Jeong Hwan Kim, Sun-Young Lee, Hyung Seok Park, Chan Sup Shim
Background/Aims: Some people have difficulty tolerating upper endoscopy. The cause of and risk factors for this are not well known. The aim of this study was to investigate the factors involved in poor cooperation during screening upper endoscopy. Methods: A total of 4,422 subjects who underwent a health inspection with upper endoscopy carried out by a single experienced endoscopist were included. We retrospectively investigated subjects' self-reporting questionnaires and medical records, including endoscopic and histologic findings...
August 22, 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/28823096/sub-chronic-exposure-to-low-concentration-of-dibutyl-phthalate-affects-anthropometric-parameters-and-markers-of-obesity-in-rats
#2
Khalid Abdul Mjaeed, Habib Ur Rehman, Muhammad Shahbaz Yousaf, Hafsa Zaneb, Imtiaz Rabbani, Sajid Khan Tahir, Muhammad Afzal Rashid
Dibutyl phthalate is an important phthalate ester extensively used in various products like plastics, adhesives, inks, pharmaceuticals, lacquers, varnishes, paper coatings, safety glasses, and cosmetics. The exposure of DBP to "one's health" is therefore inevitable. The present study focuses on elucidating the effect of low doses of DBP on anthropometric parameters and markers of obesity in rats in a 13-week study. A total of 48 rats were divided into three treatment groups as mg DBP/kg body weight per day: (a) 0 mg/kg (control), (b) 10 mg/kg (DBP-10), and (c) 50 mg/kg (DBP-50)...
August 19, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28823074/single-anastomosis-duodeno-ileal-switch-sadis-a-systematic-review-of-efficacy-and-safety
#3
Saeed Shoar, Lauren Poliakin, Rebecca Rubenstein, Alan A Saber
BACKGROUND: Owing to the possibility of weight regain after the long-term follow-up of gastric bypass patients and because of the high morbidity of biliopancreatic diversion with duodenal switch, single-anastomosis duodeno-ileal switch (SADIS) has emerged as a rescue procedure in bariatric surgery. OBJECTIVE: The purpose of this review is to summarize the literature data on SADIS. SETTING: University Hospital, NY. METHODS: A comprehensive literature review was performed through October 2016 to identify English studies on SADIS performed in human subjects...
August 19, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28823024/effect-of-kaempferia-parviflora-extract-on-knee-osteoarthritis
#4
Hiroko Kobayashi, Ryo Suzuki, Kei Sato, Takatoshi Ogami, Hiroshi Tomozawa, Masahito Tsubata, Koji Ichinose, Masaki Aburada, Wataru Ochiai, Kiyoshi Sugiyama, Tsutomu Shimada
Knee osteoarthritis (OA) is becoming more prevalent worldwide due to increases in the numbers of elderly and obese patients. Currently, pharmaceutical medicines used for the treatment of OA are for symptomatic therapy and therefore new therapeutic agents are needed. Kaempferia parviflora (KP) is a plant growing naturally in Southeast Asia and has various pharmacological effects including an anti-inflammatory effect, but no effect on OA has yet been reported. We therefore conducted a search for the effects KP and the active components of KP extract (KPE) exert on OA as well as its mechanism of action...
August 19, 2017: Journal of Natural Medicines
https://www.readbyqxmd.com/read/28822994/glucagon-like-peptide-1-receptor-agonist-stimulates-mitochondrial-bioenergetics-in-human-adipocytes
#5
Joanna Góralska, Agnieszka Śliwa, Anna Gruca, Urszula Raźny, Monika Chojnacka, Anna Polus, Bogdan Solnica, Małgorzata Malczewska-Malec
Glucagon-like peptide 1 receptor agonists (GLP-1RAs) are relatively new pharmacological agents used to normalize glucose level in type 2 diabetes. Recently, GLP-1RAs have been approved for the treatment of obesity to reduce body weight in non-diabetic patients. The extra-pancre-atic effects of GLP-1RAs, as well as their molecular mechanism of action, are still poorly understood. Thus this study was aimed to verify the hypothesis that the mechanism of action of the GLP-1RAs involves mitochondria and that GLP-1RAs administration can improve mitochondrial functions...
August 19, 2017: Acta Biochimica Polonica
https://www.readbyqxmd.com/read/28822885/matching-complex-dietary-landscapes-with-the-signalling-pathways-that-regulate-life-history-traits
#6
REVIEW
Christen K Mirth, Matthew Dw Piper
The rise in obesity in human populations has reinvigorated research focused on how nutrition impacts life history traits, including body size, lifespan, reproductive success, stress resistance and propensity for disease. Studies have ranged in their approach from identifying the molecular machinery responding to changes in nutrient levels, to understanding the hormonal changes that occur in response to diet, to mapping the response of differing life history traits over complex dietary landscapes. Connecting insights across these approaches presents significant challenges primarily because we lack information about how signalling pathways respond to dietary complexity...
August 17, 2017: Current Opinion in Genetics & Development
https://www.readbyqxmd.com/read/28822870/maternal-obesity-and-attention-related-symptoms-in-the-preterm-offspring
#7
Jelske W van der Burg, Elizabeth T Jensen, Margot van de Bor, Robert M Joseph, T Michael O'Shea, Karl Kuban, Elizabeth N Allred, Megan Scott, Scott Hunter, Stephen R Hooper, Olaf Dammann, Alan Leviton
BACKGROUND: Maternal pre-pregnancy obesity, in term-born children, is associated with an increased risk of attention problems, however this relationship has not been explored among children born extremely preterm. AIM: To estimate the risk of attention problems at age 10years in children born very preterm to overweight (i.e., body mass index (BMI) 25-29kg/m(2)) and obese (i.e., BMI≥30kg/m(2)) women relative to the risk among children born to women who were neither overweight nor obese (i...
August 17, 2017: Early Human Development
https://www.readbyqxmd.com/read/28822847/intestinal-adaptations-following-bariatric-surgery-towards-the-identification-of-new-pharmacological-targets-for-obesity-related-metabolic-diseases
#8
REVIEW
Lara Ribeiro-Parenti, Jean-Baptiste Cavin, Maude Le Gall
Although the gastrointestinal tract is the primary target of bariatric surgery, its contributions to the metabolic changes observed after surgery are still underestimated. Changes in the number of incretin-producing cells could result in the modified hormonal response seen after surgery. Additionally, the rate of absorption and consumption of glucose could contribute to the ameliorated glycaemia. Moreover, decreased intestinal permeability could prevent endotoxemia. Recently, numerous studies have focused on intestinal adaptation following bariatric surgeries...
August 17, 2017: Current Opinion in Pharmacology
https://www.readbyqxmd.com/read/28822806/pericardial-adipose-and-aromatase-a-new-translational-target-for-aging-obesity-and-arrhythmogenesis
#9
Gabriel B Bernasochi, Wah Chin Boon, Claire L Curl, Upasna Varma, Salvatore Pepe, Marianne Tare, Laura J Parry, Evdokia Dimitriadis, Stephen B Harrap, Chrishan J Nalliah, Jonathan M Kalman, Lea M D Delbridge, James R Bell
A correlation exists between the extent of pericardial adipose and atrial fibrillation (AF) risk, though the underlying mechanisms remain unclear. Selected adipose depots express high levels of aromatase, capable of converting androgens to estrogens - no studies have investigated aromatase occurrence/expression regulation in pericardial adipose. The Women's Health Initiative reported that estrogen-only therapy in women elevated AF incidence, indicating augmented estrogenic influence may exacerbate cardiac vulnerability...
August 16, 2017: Journal of Molecular and Cellular Cardiology
https://www.readbyqxmd.com/read/28822761/down-regulation-of-vascular-ppar-%C3%AE-contributes-to-endothelial-dysfunction-in-high-fat-diet-induced-obese-mice-exposed-to-chronic-intermittent-hypoxia
#10
Yanan Zhang, Chunlian Zhang, Haiou Li, Jingdong Hou
Obstructive sleep apnea (OSA), characterized by chronic intermittent hypoxia (CIH), is associated with endothelial dysfunction. The prevalence of OSA is linked to an epidemic of obesity. CIH has recently been reported to cause endothelial dysfunction in diet-induced obese animals by exaggerating oxidative stress and inflammation, but the underlying mechanism remains unclear. PPAR-γ, a ligand-inducible transcription factor that exerts anti-oxidant and anti-inflammatory effects, is down-regulated in the peripheral tissues in diet-induce obesity...
August 16, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28822712/socioeconomic-inequality-in-childhood-obesity-and-its-determinants-in-iran-a-blinder-oaxaca-decomposition
#11
Roya Kelishadi, Mostafa Qorbani, Ramin Heshmat, Shirin Djalalinia, Ali Sheidaei, Saeid Safiri, Nastaran Hajizadeh, Mohammad Esmaeil Motlagh, Gelayol Ardalan, Hamid Asayesh, Morteza Mansourian
OBJECTIVE: Childhood obesity has become a priority health concern worldwide. Socioeconomic status (SES) is one of its main determinants. This study aimed to assess the socioeconomic inequality of obesity in children and adolescents at national and provincial levels in Iran. METHODS: This multicenter cross-sectional study was conducted in 2011-2012, as part of a national school-based surveillance program performed in 40,000 students, aged 6-18-years, from urban and rural areas of 30 provinces of Iran...
August 17, 2017: Jornal de Pediatria
https://www.readbyqxmd.com/read/28822619/experiential-documentation-of-trimad-for-its-anti-obesity-potential-a%C3%A2-survey-of-ayurvedic-physicians-from-pune-city
#12
Megha Salunke, Manasi Deshpande, Supriya Bhalerao
BACKGROUND: Trimad is an Ayurvedic polyherbal formulation consisting of tubers of Mustaka (Cyperus rotundus), fruits of Vidanga (Embelia ribes) and roots of Chitraka (Plumbago zeylanica). It is recommended in Ayurveda for the management of obesity. However, there is no documented evidence about its safety and efficacy. Hence, as a first step, we carried out a survey to find out its usage by Ayurvedic physicians and their personal clinical experiences while using the formulation. METHODOLOGY: A questionnaire was designed which included questions regarding the usage, dosage, formulation, safety and tolerability of Trimad...
August 16, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28822555/influence-of-tumor-size-on-outcomes-following-pelvic-exenteration
#13
B Smith, E L Jones, M Kitano, A L Gleisner, N J Lyell, G Cheng, M D McCarter, S Abdel-Misih, F J Backes
OBJECTIVE: Pelvic exenteration (PE) is often the only curative option for locally advanced or recurrent pelvic malignancies. Despite radical surgery, recurrence risk and morbidity remain high. In this study, we sought to determine tumor size effect on perioperative outcomes and subsequent survival in patients undergoing PE. METHODS: Retrospective chart review was performed for female patients who underwent PE at two comprehensive cancer centers from 2000 to 2015...
August 16, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28822528/management-of-obesity-in-adult-asian-indians
#14
REVIEW
S Behl, A Misra
The prevalence of obesity in India is increasing and ranges from 8% to 38% in rural and 13% to 50% in urban areas. Obesity is a risk factor for development of type 2 diabetes mellitus (T2DM), hypertension, dyslipidemia, coronary heart disease and many cancers. In Asian Indians excess abdominal and hepatic fat is associated with increased risk for T2DM and cardiovascular disease. There is higher risk for development of obesity related non-communicable diseases at lower body mass index levels, compared to white Caucasians...
July 2017: Indian Heart Journal
https://www.readbyqxmd.com/read/28822508/prevalence-and-characteristics-of-resistant-hypertensive-patients-in-an-asian-population
#15
Rabia Naseem, Arsalan Majeed Adam, Fiza Khan, Adiya Dossal, Ibrahim Khan, Ammara Khan, Hannah Paul, Hafsa Jawed, Aisha Aslam, Faez Muhammad Syed, Muhammad Ahsen Niazi, Shehzeen Nadeem, Aruba Khan, Amber Zia, Mohammad Hussham Arshad
BACKGROUND: Resistant hypertension is a well-recognized clinical challenge yet there are no reported data on its prevalence in Pakistan. These patients are subjected to a higher risk of developing hypertensive complications. The objective of our study was to evaluate the prevalence and determinants of resistant hypertension in an Asian cohort of hypertensive patients. METHODS: This cross-sectional study was carried out among hypertensive patients visiting a tertiary care hospital in Karachi from September-December 2015...
July 2017: Indian Heart Journal
https://www.readbyqxmd.com/read/28822383/outcomes-experienced-by-patients-presenting-with-ventral-hernia-and-morbid-obesity-in-a-surgical-clinic
#16
Margaret A Plymale, Daniel L Davenport, John S Roth
No abstract text is available yet for this article.
August 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28822255/malnutrition-in-postacute-geriatric-care-basic-espen-diagnosis-and-etiology-based-diagnoses-analyzed-by-length-of-stay-in-hospital-mortality-and-functional-rehabilitation-indexes
#17
Dolores Sánchez-Rodríguez, Ester Marco, Cédric Annweiler, Natalia Ronquillo-Moreno, Andrea Tortosa, Olga Vázquez-Ibar, Ferran Escalada, Xavier Duran, Josep M Muniesa
OBJECTIVE: To determine the relationships between malnutrition and nutrition-related conditions according to the European Society of Clinical Nutrition and Metabolism (ESPEN) consensus and guidelines and clinical outcomes in postacute rehabilitation. METHODS: Of 102 eligible inpatients, 95 (84.5 years old, 63.2% women) fulfilled inclusion criteria: aged ≥70 years, body mass index <30kg/m(2), admission for rehabilitation. Mini-Nutritional Assessment-Short Form (MNA-SF≤11) identified patients "at risk" and ESPEN basic and etiology based definitions were applied...
August 2, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/28822233/obese-fathers-lead-to-an-altered-metabolism-and-obesity-in-their-children-in-adulthood-review-of-experimental-and-human-studies
#18
REVIEW
Fernanda Ornellas, Priscila V Carapeto, Carlos A Mandarim-de-Lacerda, Marcia B Aguila
OBJECTIVE: To discuss the recent literature on paternal obesity, focusing on the possible mechanisms of transmission of the phenotypes from the father to the children. SOURCES: A non-systematic review in the PubMed database found few publications in which paternal obesity was implicated in the adverse transmission of characteristics to offspring. Specific articles on epigenetics were also evaluated. As the subject is recent and still controversial, all articles were considered regardless of year of publication...
August 16, 2017: Jornal de Pediatria
https://www.readbyqxmd.com/read/28822064/evolution-of-29-anthropometric-nutritional-and-cardiometabolic-parameters-among-morbidly-obese-adolescents-2-years-post-sleeve-gastrectomy
#19
Wahiba Elhag, Walid El Ansari, Sama Abdulrazzaq, Ali Abdullah, Mohamed Elsherif, Israa Elgenaied
BACKGROUND: Laparoscopic sleeve gastrectomy (LSG) is a popular treatment for adolescent morbid obesity. Research on LSG outcomes among adolescents assessed a narrow range of anthropometric, nutritional, or cardiometabolic parameters, leading to an incomplete picture of these changes. We examined a wide variety of anthropometric, nutritional, and cardiometabolic parameters among adolescents before and after LSG. METHODS: We retrospectively reviewed medical charts of all obese adolescents who underwent LSG at Hamad Medical Corporation, Qatar, between January 2011 and June 2015 (N = 102)...
August 18, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28822052/bariatric-surgery-worldwide-baseline-demographic-description-and-one-year-outcomes-from-the-second-ifso-global-registry-report-2013-2015
#20
Richard Welbourn, Dimitri J Pournaras, John Dixon, Kelvin Higa, Robin Kinsman, Johan Ottosson, Almino Ramos, Bart van Wagensveld, Peter Walton, Rudolf Weiner, Natan Zundel
BACKGROUND: Five International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO) surveys since 1998 have estimated the volume and type of bariatric surgery being done in constituent member countries. These reports did not include baseline demographic descriptions. METHODS: An IFSO Global Registry pilot project in 2014 demonstrated that it was possible to amalgamate large numbers of individual patient data from different local and national database systems...
August 18, 2017: Obesity Surgery
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