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https://www.readbyqxmd.com/read/29929204/sport-participation-and-metabolic-risk-during-adolescent-years-a-structured-equation-model
#1
AndréOliveira Werneck, Danilo Rodrigues Pereira da Silva, Rômulo Araújo Fernandes, EnioRicardoVaz Ronque, Manuel J Coelho-E-Silva, Edilson Serpeloni Cyrino
Sports practice during childhood can influence health indicators in later ages through direct and indirect pathways. Thus, this study aimed to test direct and indirect pathways to the association between sports practice in childhood and metabolic risk in adolescence, adopting physical activity, adiposity, and cardiorespiratory fitness at adolescence as potential mediators. This cross-sectional study with retrospective information was conducted with 991 adolescents (579 girls, 412 boys) aged 10 to 16 y. Sports activity was self-reported in childhood (retrospective data) and physical activity evaluated in adolescence through questionnaires...
June 21, 2018: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/29929198/differential-associations-of-walking-and-cycling-with-body-weight-body-fat-and-fat-distribution-the-acti-cit%C3%A3-s-project
#2
Mehdi Menai, Hélène Charreire, Pilar Galan, Chantal Simon, Julie-Anne Nazare, Camille Perchoux, Christiane Weber, Christophe Enaux, Serge Hercberg, Léopold Fezeu, Jean-Michel Oppert
BACKGROUND: Research on the associations between walking and cycling with obesity-related phenotypes is growing but relies mostly on the use of BMI. The purpose of this study was to analyze associations of walking and cycling behaviors assessed separately with various obesity markers in French adults. METHODS: In 12,776 adult participants (71.3% women) of the on-going NutriNet Santé web-cohort, we assessed by self-report past-month walking and cycling (for commuting, errands and leisure), and obesity measures were taken during a visit at a clinical center (weight, height, waist circumference, and percent body fat by bioimpedance)...
June 22, 2018: Obesity Facts
https://www.readbyqxmd.com/read/29929107/in-utero-programming-and-early-detection-of-cardiovascular-disease-in-the-offspring-of-mothers-with-obesity
#3
REVIEW
Karolien Van De Maele, Roland Devlieger, Inge Gies
The offspring of women with obesity during their pregnancy are exposed to an altered intra-uterine environment. A subsequent influence on the cardiovascular development during fetal life is assumed. In the present thematic review, we report on the current knowledge about this early development of cardiovascular disease from fetal life until adolescence. Based on animal studies, different contributing mechanisms have been hypothesized that still need confirmation in human subjects. Insulin resistance, increased levels of leptin, chronic inflammatory state, perturbation of sympathetic tone and epigenetic modifications contribute to a suboptimal nutrient environment and changed hemodynamics...
June 9, 2018: Atherosclerosis
https://www.readbyqxmd.com/read/29929088/alcohol-consumption-frequency-or-alcohol-intake-per-drinking-session-which-has-a-larger-impact-on-the-metabolic-syndrome-and-its-components
#4
Sarah Soyeon Oh, Woorim Kim, Kyu-Tae Han, Eun-Cheol Park, Sung-In Jang
OBJECTIVES: This study investigated the relationship between drinking behavior (alcohol consumption frequency, average alcohol intake per drinking session) and the prevalence of metabolic syndrome (MetS) and its components (central obesity, raised triglycerides, decreased HDL cholesterol, raised blood pressure, raised fasting plasma glucose) in Korean men and women above the age of 20. METHODS: Our study employed data from the Korea National Health and Nutritional Examination Survey (KNHANES) for the years 2007-2013...
February 1, 2018: Alcohol
https://www.readbyqxmd.com/read/29929023/gender-difference-in-requesting-abdominoplasty-after-bariatric-surgery-based-on-five-years-of-experience-in-two-centers-in-sulaimani-governorate-kurdistan-region-iraq
#5
Hiwa O Ahmed, Sarmad H Arif, Sabah Abid Abdulhakim, Aram Kakarash, Mohammad Amin Ali Omer, Aree Majid Nuri, Hallo H Omer, Hardi Kareem Jalal, Shahen H Omer, Nashadin Aziz Muhammad
BACKGROUND: The increasing incidence of morbid obesity suggests that the quantity of bariatric surgical procedures will continue to multiply each year, many patients who have experienced massive weight loss are left with the dissatisfying consequences of loose and redundant skin, resulting in contour irregularities, an aesthetic and functional problem, and profound dissatisfaction with appearance, residual body image dissatisfaction, There is a subsequent increase in the number of patients seeking additional corrective procedures including abdominoplasty which considered as one of the most popular body-contouring procedures...
June 18, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29928982/heterogeneity-and-the-origins-of-asthma
#6
REVIEW
Rebecca Scherzer, Mitchell H Grayson
OBJECTIVE: It is a well-known fact that there is significant heterogeneity in the origins of asthma in adults and children. This article examines the roots of asthma across the ages including atopy, the role of the microbiome and viral infections, along with comorbidities/confounders such as obesity, aspirin-exacerbated respiratory disease (AERD), neutrophilic asthma, cigarette smoking and the possibility of an asthma-chronic obstructive pulmonary disease (COPD) overlap syndrome. DATA SOURCES: Data was taken from various scientific search engines including PubMed and Science Direct databases...
June 18, 2018: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29928963/replication-and-reproducibility-issues-in-the-relationship-between-c-reactive-protein-and-depression-a-systematic-review-and-focused-meta-analysis
#7
REVIEW
Sarah R Horn, Madison M Long, Benjamin W Nelson, Nicholas B Allen, Philip A Fisher, Michelle L Byrne
One of the most common inflammatory markers examined in depression is C-reactive protein (CRP). However, the magnitude of the association between CRP and depression when controlling for potentially confounding factors such as age, sex, socio-economic status, body mass index, medication and other substance use, and medical illness, is unclear. Inconsistencies in other methodological practices, such as sample collection, assaying, and data cleaning and transformation, may contribute to variations in results. We aggregate studies that examined the association between CRP and depression in two ways...
June 18, 2018: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/29928939/associations-between-acculturation-ethnic-identity-and-diet-quality-among-u-s-hispanic-latino-youth-findings-from-the-hchs-sol-youth-study
#8
Gabriela Arandia, Daniela Sotres-Alvarez, Anna Maria Siega-Riz, Elva M Arredondo, Mercedes R Carnethon, Alan M Delamater, Linda C Gallo, Carmen R Isasi, Ashley N Marchante, David Pritchard, Linda Van Horn, Krista M Perreira
BACKGROUND: Acculturation among Hispanic/Latinos has been linked to deteriorating dietary quality that may contribute to obesity risks. This study examined the relationship between acculturation, ethnic identity, and dietary quality in U.S. Hispanic/Latino youth. METHODS: This cross-sectional study included 1298 Hispanic/Latino youth ages 8-16 from the Hispanic Community Health Study/Study of Latino Youth (HCHS/SOL Youth), an ancillary study of offspring of participants in the adult HCHS/SOL cohort...
June 18, 2018: Appetite
https://www.readbyqxmd.com/read/29928852/oxygen-use-after-lung-cancer-surgery
#9
Daniel G Nicastri, Naomi Alpert, Bian Liu, Andrea Wolf, Emanuela Taioli, Benjamin V Tran, Raja Flores
BACKGROUND: There are no published reports on predictors of oxygen (O2 ) use after lung cancer surgery. The prospect of O2 use following lung cancer surgery may affect a patient's therapy choice. METHODS: The Surveillance, Epidemiology, and End Results -Medicare (SEER-Medicare) dataset was queried to identify patients diagnosed with primary lung cancer (stage I/II) who underwent surgical resection from 1994-2010. Patients with a second resection within 6 months of their first and those with preoperative O2 use were excluded...
June 18, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29928698/maternal-exercise-training-attenuates-endotoxin-induced-sepsis-in-mice-offspring
#10
Mami Yamada, Chihiro Hokazono, Mitsuharu Okutsu
Regular exercise during pregnancy can prevent offspring from several diseases, such as cardiovascular diseases, obesity, and type II diabetes during adulthood. However, little information is available about whether maternal exercises during pregnancy protect the offspring from infectious diseases, such as sepsis and multiple organ dysfunction syndrome (MODS). This study aimed to investigate whether maternal exercise training protects the offspring from endotoxin-induced septic shock in mice. Female C57BL/6 mice performed voluntary wheel exercises during pregnancy...
September 2018: Biochemistry and Biophysics Reports
https://www.readbyqxmd.com/read/29928644/the-case-chronic-kidney-disease-unmasked-by-single-subject-research
#11
Benjamin Gollasch, Oskar Wischnewski, Birgit Rudolph, Yoland-Marie Anistan, Friedrich C Luft, Maik Gollasch
We present a 42-year-old man with a BMI of 32, who was referred because of proteinuria and decreased renal function. We were impressed by his markedly muscular physique. A renal biopsy was performed, which showed focal segmental glomerular sclerosis (FSGS). Is this patient merely an obese person with FSGS or is something else going on here? We performed extensive clinical and laboratory examinations, genetic testing, and anthropometric data monitoring over time. We transferred our methodology for routine FSGS mutation screening (Sanger sequencing) to the Ion Torrent PGM platform with a new custom-targeted NGS gene panel (Ion Ampliseq FSGS panel) and tested the performance of the system in two cohorts of patients with FSGS...
May 2018: Case Reports in Nephrology and Dialysis
https://www.readbyqxmd.com/read/29928262/coffee-is-associated-with-lower-breast-tumor-insulin-like-growth-factor-receptor-1-levels-in-normal-weight-patients-and-improved-prognosis-following-tamoxifen-or-radiotherapy-treatment
#12
Sofie Björner, Ann H Rosendahl, Helga Tryggvadottir, Maria Simonsson, Karin Jirström, Signe Borgquist, Carsten Rose, Christian Ingvar, Helena Jernström
Coffee is associated with decreased breast cancer risk, but the impact of body mass index (BMI) in combination with coffee consumption on prognosis is unclear. The suppressive effect of coffee constituents on the insulin-like growth factor receptor 1 (IGF1R) levels in breast cancer cells may play a role. The aim was to investigate the prognostic impact of coffee consumption and possible associations with tumor-specific IGF1R protein expression and BMI in a population-based cohort in Sweden, comprising 1,014 primary breast cancer patients without pretreatment enrolled 2002-2012 and followed for up to 13 years...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29928260/liver-enlargement-predicts-obstructive-sleep-apnea-hypopnea-syndrome-in-morbidly-obese-women
#13
Giovanna Scartabelli, Giorgia Querci, Letizia Marconi, Giovanni Ceccarini, Paolo Piaggi, Paola Fierabracci, Guido Salvetti, Giovanni Cizza, Salvatore Mazzeo, Jacopo Vitti, Slava Berger, Antonio Palla, Ferruccio Santini
Obstructive sleep apnea-hypopnea syndrome (OSAHS) is frequently present in patients with severe obesity, but its prevalence especially in women is not well defined. OSAHS and non-alcoholic fatty liver disease are common conditions, frequently associated in patients with central obesity and metabolic syndrome and are both the result of the accumulation of ectopic fat mass. Identifying predictors of risk of OSAHS may be useful to select the subjects requiring instrumental sleep evaluation. In this cross-sectional study, we have investigated the potential role of hepatic left lobe volume (HLLV) in predicting the presence of OSAHS...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29928138/the-influences-of-bariatric-surgery-on-hemoglobin-a1c-in-a-sample-of-obese-patients-in-saudi-arabia
#14
Anwar E Ahmed, Wala R Alanazi, Rayan A Ahmed, Wijdan AlJohi, Doaa A AlBuraikan, Budor A AlRasheed, Bashayr I ALMuqbil, Ali A Al-Zahrani, Zeyad M Yousef, Hamdan Al-Jahdali
Background: Although the frequency of surgical weight loss interventions has increased in Saudi Arabia, literature describing the clinical outcomes of bariatric surgery in Saudi Arabia is limited. This study aimed to assess whether weight loss intervention improves hemoglobin A1c (HbA1c) in obese patients and to identify its associated factors. Patients and methods: A retrospective study was carried out on 318 patients with obesity class 1 or higher (body mass index [BMI] ≥ 30 kg/m2 ) who underwent laparoscopic sleeve gastrectomy or Roux-en-Y gastric bypass at King Abdulaziz Medical City in Riyadh, Saudi Arabia, between January 1, 2001 and March 31, 2017...
2018: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
https://www.readbyqxmd.com/read/29928131/identification-of-cd24-as-a-marker-for-tumorigenesis-of-melanoma
#15
Ming-Rui Tang, Jia-Yan Guo, Di Wang, Nan Xu
Objective: Cutaneous melanoma (CM) is a common skin cancer. Surgery is still the primary treatment for CM, as melanoma is resistant to chemotherapy. In the recent years, it has been found that cancer stem-like cells (CSCs) are responsible for this drug resistance. CD24 is a widely used marker to isolate CSCs. In this study, we aimed to analyze the properties of CD24+ and CD24- subpopulation of melanoma cells. Materials and methods: We isolated CD24+ cells CSCs using magnetic-activated cell sorting system...
2018: OncoTargets and Therapy
https://www.readbyqxmd.com/read/29928054/achilles-tendon-structure-is-negatively-correlated-with-body-mass-index-but-not-influenced-by-statin-use-a-cross-sectional-study-using-ultrasound-tissue-characterization
#16
Agnetha de Sá, David A Hart, Karim Khan, Alexander Scott
INTRODUCTION: Statins are widely used to inhibit cholesterol production in the liver among people with hypercholesterolemia. A recent epidemiological study in the UK has shown that statin use (unlike elevated BMI) is not associated with an increased risk of Achilles tendon rupture. However, because of laboratory reports suggesting a negative influence of statins on tenocyte metabolism, we decided to directly compare the Achilles tendon structure (cross-sectional area and longitudinal collagen organization) in regular statin users compared to non-users...
2018: PloS One
https://www.readbyqxmd.com/read/29928018/polymorphisms-in-the-receptor-for-advanced-glycation-end-products-rage-gene-and-circulating-rage-levels-as-a-susceptibility-factor-for-non-alcoholic-steatohepatitis-nash
#17
Rohini Mehta, Gladys Shaw, Peter Masschelin, Sean Felix, Munkzhul Otgonsuren, Ancha Baranova, Zachary Goodman, Zobair Younossi
Non-alcoholic fatty liver disease (NAFLD) is a hepatic manifestation of metabolic syndrome and major cause of chronic liver disease in developed countries. Its prevalence is increasing in parallel with the prevalence of obesity and other components of the metabolic syndrome. As the liver is central to the clearance and catabolism of circulating advanced glycosylation end-products (AGEs), AGEs and their cognate receptors-RAGE (receptor for AGEs) system might be involved in NAFLD in obese patients. To examine this, we investigated four common polymorphisms of RAGE gene: 1704G/T (rs184003), G82S (rs2070600), -374T/A (rs1800624) and -429T/C (rs1800625) in 340 obese patients with metabolic syndrome...
2018: PloS One
https://www.readbyqxmd.com/read/29928005/implicit-and-explicit-changes-in-body-satisfaction-evoked-by-body-size-illusions-implications-for-eating-disorder-vulnerability-in-women
#18
Catherine Preston, H Henrik Ehrsson
Dissatisfaction with one's body is a widespread issue in modern society and has been linked to vulnerability for developing eating disorders. Recent studies have demonstrated a direct relationship between body perception and body satisfaction by manipulating perceived body size using multisensory body illusions. However, how these body size illusions influence implicit affective experience has not previously been examined. The current experiment used an established full-body ownership illusion paradigm to induce feelings of illusory obesity in male and female participants...
2018: PloS One
https://www.readbyqxmd.com/read/29927995/does-mammogram-attendance-influence-participation-in-cervical-and-colorectal-cancer-screening-a-prospective-study-among-1856-french-women
#19
Aurélie Bertaut, Julien Coudert, Leila Bengrine, Vincent Dancourt, Christine Binquet, Serge Douvier
BACKGROUND: We aimed to determine participation rates and factors associated with participation in colorectal (fecal occul blood test) and cervical cancer (Pap-smear) screening among a population of women participating in breast cancer screening. METHODS: From August to October 2015, a self-administered questionnaire was sent by post to 2 900 women aged 50-65, living in Côte-d'Or, France, and who were up to date with mammogram screening. Polytomic logistic regression was used to identify correlates of participation in both cervical and colorectal cancer screenings...
2018: PloS One
https://www.readbyqxmd.com/read/29927903/expression-of-the-marburg-i-single-nucleotide-polymorphism-mi-snp-and-the-marburg-ii-single-nucleotide-polymorphism-mii-snp-of-the-factor-vii-activating-protease-fsap-gene-and-risk-of-coronary-artery-disease-cad-a-pilot-study-in-a-single-population
#20
Mariana S Parahuleva, Bernhard Schieffer, Michael Klassen, Michael Worsch, Behnoush Parviz, Hans Hölschermann
BACKGROUND Factor VII-activating protease (FSAP) has a role in vascular inflammation and may have a role coronary artery disease (CAD). The aim of this study was to investigate the association between two naturally occurring single nucleotide polymorphisms (SNPs) in the FSAP gene and the risk of coronary artery disease (CAD). MATERIAL AND METHODS Of 733 patients, 173 patients had symptoms of angina, and 560 patients had CAD confirmed by coronary angiography. All patients were genotyped for SNPs of the FSAP gene, Marburg I (MI-SNP) and Marburg II (MII-SNP), using 5' exonuclease TaqMan assays...
June 21, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
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