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https://www.readbyqxmd.com/read/29791700/closing-the-gap-novel-abdominal-wound-closure-techniques
#1
James Dana Kondrup, Alaina M Qayyum
Traditionally, surgical procedures within the realm of both general and gynecological surgery employ the use of staples and interrupted sutures that run continuously with knot tying or subcuticular sutures to ensure closure of large wound incisions, subcuticular incisions, and fascial repair. However, these methods may not always be cosmetically favorable and, thus, result in an unpleasant outcome for the patient, adding to their surgery-related stress. It is, therefore, imperative that surgeons and gynecologists are aware of alternative methods of wound closure that are not only cosmetically favorable, but also ensure rapid wound recovery and infection control...
June 1, 2018: Surgical Technology International
https://www.readbyqxmd.com/read/29787547/interrupted-versus-continuous-fascial-closure-in-patients-undergoing-emergent-laparotomy-a-randomized-controlled-trial
#2
Thomas Peponis, Jordan D Bohnen, Sandra Muse, Eva Fuentes, Gwendolyn M van der Wilden, Ali Mejaddam, Hasan Alam, Haytham M A Kaafarani, Peter J Fagenholz, David R King, D Dante Yeh, George C Velmahos, Marc A de Moya
BACKGROUND: The optimal method of fascial closure, interrupted versus continuous (IFC and CFC respectively) has never been studied exclusively in the setting of emergency surgery. We hypothesized that IFC decreases postoperative incisional hernia development following emergent laparotomies. METHODS: Between August 2008 and September 2015, patients undergoing emergent laparotomies were consented and randomly assigned to either IFC or CFC. Patients were followed postoperatively for at least three months and assessed for incisional hernia, dehiscence, or wound infection...
May 4, 2018: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29782983/an-in-vivo-biocompatibility-study-of-surgical-meshes-made-from-bacterial-cellulose-modified-with-chitosan
#3
Joanna Piasecka-Zelga, Piotr Zelga, Joanna Szulc, Justyna Wietecha, Danuta Ciechańska
Bacterial cellulose modified with chitosan (MBC) is an innovative biomaterial used in regenerative medicine which may potentially improve treatment outcomes mesh for hernia repair surgery by facilitating better absorption in native tissue with less risk of mesh-related infections. The aim of the present study was to evaluate the biocompatibility of mesh based on MBC, and determine whether immunological reactions occur due to hypersensitivity to the implants. Forty five Imp:WIST rats were randomly assigned to be implanted with one of three mesh types: simple polypropylene mesh (n = 15), mesh modified by bacterial cellulose only (n = 15) and MBC mesh (n = 15) and evaluated after one and three months following intramuscular implantation...
May 18, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29759500/antibacterial-envelope-is-associated-with-low-infection-rates-after-implantable-cardioverter-defibrillator-and-cardiac-resynchronization-therapy-device-replacement-results-of-the-citadel-and-centurion-studies
#4
Charles A Henrikson, M Rizwan Sohail, Helbert Acosta, Eric E Johnson, Lawrence Rosenthal, Roman Pachulski, Dan Dan, Walter Paladino, Farhat S Khairallah, Kent Gleed, Ibrahim Hanna, Alan Cheng, Daniel R Lexcen, Grant R Simons
OBJECTIVES: This study sought to determine whether the nonabsorbable TYRX Antibacterial Envelope (TYRX) reduces major cardiovascular implantable electronic device (CIED) infections 12 months after implant. BACKGROUND: TYRX is a monofilament polypropylene mesh impregnated with minocycline and rifampin specifically designed to hold a CIED in place and elute antimicrobials over time. There are limited data on its ability to reduce CIED infections. METHODS: We prospectively enrolled patients who underwent generator replacement with an implantable cardioverter-defibrillator (ICD) or cardiac resynchronization therapy device (CRT), treated with TYRX...
October 2017: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29756281/lightweight-highly-permeable-biocompatible-and-antiadhesive-composite-meshes-for-intraperitoneal-repairs
#5
Minhui Hu, Xidong Lin, Rongkang Huang, Keli Yang, Yeru Liang, Xingcai Zhang, Hui Wang, Dingcai Wu
Ventral hernia is a public health issue and millions of meshes are used to repair abdominal wall defects every year. Polypropylene-based composite meshes represent an important class of materials for intraperitoneal repair, but the meshes generally give rise to infection, seroma, migration, and adhesion, leading to severe consequence or even reoperation. Here, a facile and versatile one-way fabrication of lightweight, highly permeable, and biocompatible composite meshes with superior antiadhesion properties is proposed by modifying polypropylene meshes with well-defined polydopamine nanocoating...
May 14, 2018: Macromolecular Bioscience
https://www.readbyqxmd.com/read/29751529/the-use-and-safety-of-tnf-inhibitors-during-pregnancy-in-women-with-psoriasis-a-review
#6
REVIEW
Cæcilie Bachdal Johansen, Espen Jimenez-Solem, Ann Haerskjold, Freja Lærke Sand, Simon Francis Thomsen
Psoriasis is a chronic immune-mediated inflammatory disease affecting women of childbearing potential. Biologic agents, notably Tumor Necrosis Factor inhibitors (TNFi), are the only current non-contraindicated systemic treatment option during pregnancy. TNFi comprised of complete immunoglobulin G (IgG) antibodies antibodies (adalimumab, golimumab, and infliximab) actively cross the placenta from the second trimester and are detectable in the child up to one year postpartum. Data on safety of TNFi are conflicting; however a trend towards drug-specific harm has been reported, with increased risk of congenital malformations and preterm birth...
May 3, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29750327/do-nano-crystalline-silver-coated-hernia-grafts-reduce-infection
#7
Elif Nergiz Adıgüzel, Ebru Esen, Gökçe Aylaz, Betül Keskinkılıç Yağız, Mehmet Kıyan, Aydın Doğan, Ali Ekrem Ünal
PURPOSE: Inguinal hernia repairs are the most common interventions in adults in general surgery clinics. Depending on the type of mesh and repair, the incidence of mesh-related infection ranges from 0.6 to 8%. Methicillin-resistant Staphylococcus aureus is the most common microorganism causing graft infection. The aim of this study was to investigate the efficacy of nano-crystalline silver-coated polypropylene grafts against graft infection created with MRSA in rats. METHODS: A total of 60 female, Wistar albino rats were used in the study...
May 10, 2018: World Journal of Surgery
https://www.readbyqxmd.com/read/29746262/clinical-comparison-of-surgical-constructs-for-anterior-cervical-corpectomy-and-fusion-in-patients-with-cervical-spondylotic-myelopathy-or-ossified-posterior-longitudinal-ligament-a-systematic-review-and-meta-analysis
#8
Timothy R Niedzielak, Joseph Palmer, John P Malloy
STUDY DESIGN: This is a systematic review and meta-analysis. OBJECTIVE: To examine the differences in outcomes among current constructs and techniques for anterior cervical corpectomy and fusion (ACCF) in patients with single or multiple level cervical myelopathy (CM) secondary to cervical spondylosis or ossified posterior longitudinal ligament. SUMMARY OF BACKGROUND DATA: The natural history of CM can be a progressive disease process. In such cases, where surgical decompression is indicated to halt the progression, ACCF is typically chosen for pathology located posterior to the vertebral body...
May 9, 2018: Clinical Spine Surgery
https://www.readbyqxmd.com/read/29736917/use-of-cancellous-bone-grafting-to-promote-granulation-tissue-in-a-distal-limb-wound-in-a-dog
#9
K Barnes, O Lanz, S Barry, K Aulakh
A 5-year-old female spayed Shetland sheepdog presented for evaluation of bandage sores on the left pelvic limb after a splint was placed to stabilise a digit fracture incurred approximately 2 weeks previously. Multiple areas of necrosis were identified upon bandage removal. After debridement of devitalised tissue, a 4 cm wound on the plantar surface of the metatarsal bones (with exposed bone and tendons) remained. The Papineau technique (which involves removal of infected or necrotic tissue, placement of autogenous cancellous bone graft within a wound, and delayed skin closure) was used to treat this wound...
May 7, 2018: Journal of Small Animal Practice
https://www.readbyqxmd.com/read/29732505/prophylactic-mesh-reinforcement-of-stomas-a-cost-effectiveness-meta-analysis-of-randomised-controlled-trials
#10
J M Findlay, C P J Wood, C Cunningham
BACKGROUND: Previous meta-analyses of randomised controlled trials (RCTs) have suggested a reduction in parastomal hernias (PSH) with prophylactic mesh. However, concerns persist regarding variably supportive evidence and cost. We performed an updated systematic review and meta-analysis to inform a novel cost-effectiveness analysis. METHODS: The PubMed, EMBASE and Cochrane Centre Register of Controlled Trials databases were searched (February 2018). We included RCTs assessing mesh reinforcement during stoma formation...
May 7, 2018: Techniques in Coloproctology
https://www.readbyqxmd.com/read/29712612/determination-of-proper-timing-for-the-placement-of-intra-abdominal-mesh-after-incidental-enterotomy-in-a-rodent-model-rattus-norvegicus
#11
Kathryn B Muir, Charles P Smoot, Jennifer L Viera, Maxwell R Sirkin, Brian Yoon, Julia Bader, Rebecca Smiley, Danielle Holt, Luke J Hofmann
Controversy exists regarding the appropriate timing for placement of permanent intra-abdominal mesh after inadvertent enterotomy during elective hernia repair. The aim of this study was to examine mesh placement at variable postoperative periods and the subsequent risk of infection. Fifty rodents were divided into five groups. Groups one to four underwent laparotomy, enterotomy, and repair. Physiomesh® was placed at the index operation one, three, or seven days postoperatively in Groups 1, 2, 3, and 4. Group 5 underwent mesh placement only...
April 1, 2018: American Surgeon
https://www.readbyqxmd.com/read/29707504/tracheobronchoplasty-for-tracheomalacia
#12
Cameron D Wright, Douglas J Mathisen
Tracheobronchomalacia is an uncommon acquired disorder of the central airways. Common symptoms include dyspnea, constant coughing, inability to raise secretions and recurrent respiratory infections. Evaluation includes an inspiratory-expiratory chest computed tomography (dynamic CT), an awake functional bronchoscopy and pulmonary function studies. Patients with significant associated symptoms and severe collapse on CT and bronchoscopy are offered membraneous wall plication. Tracheobronchoplasty is performed through a right thoracotomy...
March 2018: Annals of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/29701099/management-of-extra-articular-segmental-defects-in-long-bone-using-a-titanium-mesh-cage-as-an-adjunct-to-other-methods-of-fixation
#13
N Attias, A M Thabet, G Prabhakar, J A Dollahite, R J Gehlert, T A DeCoster
Aims This study reviews the use of a titanium mesh cage (TMC) as an adjunct to intramedullary nail or plate reconstruction of an extra-articular segmental long bone defect. Patients and Methods A total of 17 patients (aged 17 to 61 years) treated for a segmental long bone defect by nail or plate fixation and an adjunctive TMC were included. The bone defects treated were in the tibia (nine), femur (six), radius (one), and humerus (one). The mean length of the segmental bone defect was 8.4 cm (2.2 to 13); the mean length of the titanium mesh cage was 8...
May 1, 2018: Bone & Joint Journal
https://www.readbyqxmd.com/read/29686737/chikungunya-and-diabetes-what-do-we-know
#14
REVIEW
Francisca Kalline de Almeida Barreto, Renan Magalhães Montenegro, Virginia Oliveira Fernandes, Rhaquel Oliveira, Lívia Aline de Araújo Batista, Akhtar Hussain, Luciano Pamplona de Góes Cavalcanti
Background: Chikungunya (CHIK) is a viral disease transmitted by mosquitoes. The first cases in Brazil were confirmed in 2014. Between 2016 and 2017, over 300,000 cases were identified during this period, with nearly 300 deaths. The clinical manifestations, pathogenesis and risk factors for occurrence of severe cases are not yet well understood, although it is known that the severity of the cases is associated with the presence of comorbidities, especially diabetes mellitus (DM). Objective: To review the medical literature for the associations between DM and CHIK and to understand the potential impact on metabolic state and its complications...
2018: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/29681051/voluminous-urethral-stone-a-very-rare-complication-after-male-suburethral-sling-surgery-as-a-result-of-sling-erosion-into-proximal-urethra
#15
Ioan Scarneciu, Cristian Andrei, Camelia Scarneciu, Aura Mihaela Lupu, Ovidiu Gabriel Bratu, Sorin Lupu
Male sling for urinary incontinence is usually accompanied by very good results, with a small number of complications,but, when appear, they may be redundant. Voluminous urethral stone developed on suburethral sling as a result of sling erosion into the proximal urethra is an extremely rare complication (following the analysis of cases published on the internet, the authors of this article no longer identified another similar case). We present the case of a patient who presented in our clinic for severe and permanent urinary incontinence, perineal discomfortand pain that was influenced by position...
April 21, 2018: Urology Journal
https://www.readbyqxmd.com/read/29675591/transperineal-rectocele-repair-with-biomesh-updating-of-a-tertiary-refer-center-prospective-study
#16
Giorgio Lisi, M Campanelli, S Grande, M Grande, D Mascagni, G Milito
PURPOSE: Symptomatic rectocele results in obstructed defecation and constipation. Surgical repair may provide symptomatic relief. A variety of surgical procedures have been used in the rectocele repair to enhance anatomical and functional results and to improve long-term outcomes. METHODS: In this prospective study, we treated 25 selected women suffering from simple symptomatic rectocele with transperineal repair using porcine dermal acellular collagen matrix Biomesh (Permacol®)...
April 19, 2018: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29663944/repair-of-a-large-ventral-hernia-in-a-rhesus-macaque-macaca-mulatta-by-using-an-abdominal-component-separation-technique
#17
Steve J Kempton, Jacqueline S Israel, Saverio Capuano Iii, Samuel O Poore
Here we present a 32-y-old rhesus macaque (Macaca mulatta) with a large recurrent ventral incisional hernia. The initial surgery included midline celiotomy for treatment of endometriosis, in which the animal developed a hernia that was repaired with interposition of mesh. Hernia recurrence at 1 y resulted in a defect measuring 7 × 13 cm, with loss of abdominal domain. Skin breakdown was noted with areas of exposed mesh through the skin with associated acute on chronic infection. Clinically, the animal was lethargic, not eating, and failing to thrive...
April 2, 2018: Comparative Medicine
https://www.readbyqxmd.com/read/29649079/in-search-of-mobile-applications-for-urogynecology-providers
#18
Shannon L Wallace, Shailja Mehta, Sara Farag, Robert S Kelley, Katherine T Chen
INTRODUCTION: Thousands of medical applications (apps) are available for mobile devices. Finding accurate, health care provider-centered apps may be time consuming and frustrating for urogynecologists. The objective of this study was to identify and evaluate urogynecology (urogyn) apps using a modified APPLICATIONS scoring system. MATERIALS AND METHODS: Urogyn apps were identified from the Apple iTunes and Google Play Stores using the following 10 MeSH terms: urogynecology, incontinence, prolapse, urinary tract infection, pelvic surgery, fecal incontinence, defecation disorder, voiding disorder, urethral diverticulum, and fistula...
April 11, 2018: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/29643729/resterilized-polypropylene-mesh-for-inguinal-hernia-repair
#19
Isaac Assam Udo, Ifeanyi A Onwuezobe, Kingsley U Umeh
Purpose: The use of prosthetic biomaterials for reconstructing and reinforcing the posterior wall of the inguinal canal reduces the incidence of hernia recurrence. Cost, availability of mesh, and perhaps reluctance to adopt a new technique are factors which prevent widespread practice of hernioplasty in low-resource settings. Use of resterilized mesh significantly reduces the cost of hernioplasty and is safe. Patients and Methods: Sheets of 30 cm × 30 cm polypropylene mesh were cut into 16 cm × 8 cm to produce mesh strips which were repackaged into SELFSEAL® (Medical Action Industries Inc...
January 2018: Nigerian Journal of Surgery: Official Publication of the Nigerian Surgical Research Society
https://www.readbyqxmd.com/read/29602715/original-and-modified-technique-of-tie-over-dressing-method-and-application-in-burn-patients
#20
Rebecca Bern, Kevin Serror, Rémi Alvo, Marc Chaouat, Maurice Mimoun, Magali Schmidt, David Boccara
In burn patients, meshed split thickness skin grafts are commonly used on large and non-flat areas whom immobilization is difficult to achieve. The frequent mobilizations of burn patients can make the graft slip and prevent the revascularization and therefore the taking of the skin graft. In order to prevent this pitfall, we modified and adapted the tie-over dressing procedure. The giant running tie-over dressing enables large skin grafts to be applied to their wound bed and therefore helps revascularization...
March 27, 2018: Burns: Journal of the International Society for Burn Injuries
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