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https://www.readbyqxmd.com/read/28922241/a-shift-in-the-orbit-immediate-endoscopic-reconstruction-after-transnasal-orbital-tumors-resection
#1
Giacomo Colletti, Alberto M Saibene, Federico Pessina, Marco Duvina, Fabiana Allevi, Giovanni Felisati, Federico Biglioli
Endoscopic endonasal resection of orbital lesions is a safe and common approach. Nevertheless, medial orbital wall defects following the procedure are not routinely addressed, potentially leading to diplopia and enophthalmos. In this article, the authors propose a new technique for purely endoscopic endonasal reconstruction of orbital wall defects following endoscopic endonasal resection of orbital lesions.The patient, a 43-year-old male, suffering from right exophthalmos and diplopia due to a venous malformation of the right orbit underwent endoscopic endonasal resection of the mass...
September 15, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28917016/predictors-of-outpatient-resource-utilization-following-ventral-and-incisional-hernia-repair
#2
Alex Wade, Margaret A Plymale, Daniel L Davenport, Sara E Johnson, Vashisht V Madabhushi, Erica Mastoroudis, Charlie Tancula, John Scott Roth
INTRODUCTION: Little is known about the predictors of increased ambulatory costs following open ventral and incisional hernia repair (VIHR); however, postoperative complications would be expected to be associated with an increased burden on outpatient resources. The purpose of this study is to evaluate the impact of perioperative factors on outpatient resource utilization following VIHR. METHODS: With IRB approval, the surgery scheduling system was queried to identify all cases of VIHR done at our institution over 3 years...
September 15, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28903762/mesh-penetrating-the-cecum-and-bladder-following-inguinal-hernia-surgery-a-case-report
#3
Hiroshi Asano, Saori Yajima, Yoshie Hosoi, Makoto Takagi, Hiroyuki Fukano, Yasuhiro Ohara, Nozomi Shinozuka, Takaya Ichimura
BACKGROUND: Tension-free repair using mesh is a common inguinal hernia surgical procedure. However, various complications such as mesh-related infection and recurrence may develop as a result. Moreover, although rare, there are also reports of intestinal obstruction caused by adhesion of the mesh to the intestinal wall and cases of mesh migration into various organs. Here, we report our experience with a patient in whom mesh extraction was performed due to migration of mesh into the intestinal tract following inguinal hernia surgery and formation of a fistula with the bladder...
September 14, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28901533/characteristics-of-different-mesh-types-for-abdominal-wall-repair-in-an-experimental-model-of-peritonitis
#4
R Kaufmann, A P Jairam, I M Mulder, Z Wu, J Verhelst, S Vennix, L J X Giesen, M C Clahsen-van Groningen, J Jeekel, J F Lange
BACKGROUND: The use of synthetic mesh to repair a potentially contaminated incisional hernia may lead to higher failure rates. A biological mesh might be considered, but little is known about long-term results. Both biological and synthetic meshes were investigated in an experimental model of peritonitis to assess their characteristics in vivo. METHODS: Male Wistar rats were randomized into five groups and peritonitis was induced. A mesh was implanted after 24 h...
September 13, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28894904/factors-influencing-the-outcome-of-surgery-for-pelvic-organ-prolapse
#5
Katja Stenström Bohlin, Maud Ankardal, Emil Nüssler, Håkan Lindkvist, Ian Milsom
INTRODUCTION AND HYPOTHESIS: Pelvic organ prolapse (POP) surgery is a common gynecological procedure. Our aim was to assess the influence of obesity and other risk factors on the outcome of anterior and posterior colporrhaphy with and without mesh. METHODS: Data were retrieved from the Swedish National Register for Gynecological Surgery on 18,554 women undergoing primary and repeat POP surgery without concomitant urinary incontinence (UI) surgery between 2006 and 2015...
September 11, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28894739/immune-modulating-activity-of-hydrogel-microparticles-contributes-to-the-host-defense-in-a-murine-model-of-cutaneous-anthrax
#6
Allison L Teunis, Taissia G Popova, Virginia Espina, Lance A Liotta, Serguei G Popov
We recently reported that the open-mesh (0.7 μ) polyacrylamide microparticles (MPs) with internally-coupled Cibacron affinity dye demonstrate protective effect in mice challenged into footpads with high doses (200 LD50) of anthrax (Sterne) spores. A single injection of MPs before spore challenge reduces inflammatory response, delays onset of mortality and promotes survival. In this study, we show that the effect of MPs was substantially increased at the lower spore dose (7 LD50). The inflammation of footpads was reduced to the background level, and 60% of animals survived for 16 days while all untreated infected animals died within 6 days with strong inflammation...
2017: Frontiers in Molecular Biosciences
https://www.readbyqxmd.com/read/28894654/evaluation-of-a-novel-hybrid-viable-bioprosthetic-mesh-in-a-model-of-mesh-infection
#7
Ally Ha, Erik T Criman, Wendy E Kurata, Karen W Matsumoto, Lisa M Pierce
BACKGROUND: The reported incidence of mesh infection in contaminated operative fields is as high as 30% regardless of material used. Our laboratory previously showed that augmenting acellular bioprosthetic mesh with allogeneic mesenchymal stem cells (MSC) enhances resistance to bacterial colonization in vivo and preserves mesh integrity. This study's aim was to determine whether augmentation of non-crosslinked porcine dermis (Strattice) with commercially available, cryopreserved, viable MSC-containing human placental tissue (Stravix) similarly improves infection resistance after inoculation with Escherichia coli (E...
August 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28871371/management-of-skin-and-subcutaneous-tissue-in-complex-open-abdominal-wall-reconstruction
#8
REVIEW
I Khansa, J E Janis
PURPOSE: Open abdominal wall reconstruction is often a complex endeavor, usually performed on patients with multiple risk factors and co-morbidities. METHODS: In this article, we review soft tissue management techniques that can optimize the skin and subcutaneous tissue, with the goal of reducing surgical-site occurrences. RESULTS: Regardless of the hernia repair technique used, outcomes can be highly dependent on the appropriate management of the skin and subcutaneous tissue...
September 4, 2017: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://www.readbyqxmd.com/read/28869666/comprehensive-guidance-for-antibiotic-dosing-in-obese-adults
#9
Lina Meng, Emily Mui, Marisa K Holubar, Stan C Deresinski
BACKGROUND: Physiologic alterations seen in obesity commonly impact the pharmacokinetics (PK) and pharmacodynamics (PD) of antibiotics and may result in suboptimal dosing in this expanding but understudied population. Much of the published clinical and PK evidence to date consists of small patient populations and are retrospective with, not infrequently, heterogenous results that, in some cases, are contradictory. In the last 10 years, additional antimicrobial PK/PD and clinical data encompassing prolonged infusion strategies and examination of critically ill populations has emerged to inform antimicrobial dosing in obesity...
September 4, 2017: Pharmacotherapy
https://www.readbyqxmd.com/read/28869335/generation-and-evaluation-of-novel-stromal-cell-containing-tissue-engineered-artificial-stromas-for-the-surgical-repair-of-abdominal-defects
#10
M A Martin-Piedra, I Garzón, A Gómez-Sotelo, E Garcia-Abril, B D Jaimes-Parra, M López-Cantarero, M Alaminos, A Campos
BACKGROUND: Repair of abdominal wall defects is one of the major clinical challenges in abdominal surgery. Most biomaterials are associated to infection and severe complications, making necessary safer and more biocompatible approaches. AIM: In the present work, we combined the adequate mechanical properties of synthetic polymer meshes with tissue-engineered matrices containing stromal mesenchymal cells to generate a novel cell-containing tissue-like artificial stroma (SCTLAS) for use in abdominal wall repair...
September 4, 2017: Biotechnology Journal
https://www.readbyqxmd.com/read/28859915/viral-bronchiolitis-in-young-infants-new-perspectives-for-management-and-treatment
#11
REVIEW
Mauricio T Caballero, Fernando P Polack, Renato T Stein
OBJECTIVE: The aim of this review was to address advances in management and treatment of acute viral bronchiolitis in infants. SOURCES: A systematic review search was made including all articles published in English between 2010 and 2017, and available in the electronic databases PubMed and Cochrane Central Register of Controlled Trials (CENTRAL) and specialized register of the Acute Respiratory Infections Group (Cochrane review group). The following MESH terms in English were included, using different Boolean operators for the search strategy: "bronchiolitis, viral," "diagnosis," "epidemiology," "etiology," "therapy," "virology," "prevention and control," "respiratory syncytial virus, human...
August 30, 2017: Jornal de Pediatria
https://www.readbyqxmd.com/read/28856865/laparoscopic-extraperitoneal-uterine-suspension-with-suture-line-instead-of-mesh
#12
J Liang, G Chen, L Deng, F J Liu, L J Wu, Q Li, X Shen, Y J Yang, B Ling
OBJECTIVE: To compare the safety and effectiveness of two different materials (mesh and suture line) used in laparoscopic extraperitoneal uterine suspension. DESIGN: A retrospective observational study. SETTING: Gynaecology departments in two hospitals in China. POPULATION: Women with symptomatic pelvic organ prolapse (POP) of stage II or higher. METHODS: The women were divided into two groups according to the two different materials for laparoscopic extraperitoneal uterine suspension: mesh or suture line...
August 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28832246/decreasing-surgical-site-infections-after-ventral-hernia-repair-a-quality-improvement-initiative
#13
Deepa V Cherla, Julie L Holihan, Juan R Flores-Gonzalez, Debbie F Lew, Richard J Escamilla, Tien C Ko, Lillian S Kao, Mike K Liang
BACKGROUND: Surgical site infections (SSIs) remain prevalent after ventral hernia repair (VHR). In 2013-2014, a safety-net academic hospital initiated a two-pronged quality-improvement (QI) project: (1) Development and implementation of evidence-based guidelines; and (2) creation of a specialized hernia clinic to manage challenging patients and complex ventral hernias. Our objective was to decrease SSI rates after elective VHR. METHODS: The primary outcome was SSI 30 days post-operatively, which was assessed in aggregate and with a stratified analysis based on case complexity using the χ(2) test...
August 23, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28831335/subcutaneously-placed-breast-implants-after-a-skin-sparing-mastectomy-do-we-always-need-adm
#14
Apresh Singla, Animesh Singla, Eric Lai, David Caminer
Immediate breast reconstruction is an acceptable treatment option after mastectomy for prophylaxis of early breast cancer. Different options exist for implant placement, incision technique, patient suitability, and institutional experience. This article is a case series exploring the feasibility and outcomes of patients undergoing immediate breast reconstruction using skin-sparing mastectomy without mesh or acellular dermal matrix (ADM) and with a vertical inframammary incision. METHODS: A single-institution retrospective analysis was performed for all patients who underwent immediate single-stage reconstruction with subcutaneous silicon implants without ADM between 2009 and 2014 inclusive...
July 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28829367/past-present-and-future-of-surgical-meshes-a-review
#15
REVIEW
Karen Baylón, Perla Rodríguez-Camarillo, Alex Elías-Zúñiga, Jose Antonio Díaz-Elizondo, Robert Gilkerson, Karen Lozano
Surgical meshes, in particular those used to repair hernias, have been in use since 1891. Since then, research in the area has expanded, given the vast number of post-surgery complications such as infection, fibrosis, adhesions, mesh rejection, and hernia recurrence. Researchers have focused on the analysis and implementation of a wide range of materials: meshes with different fiber size and porosity, a variety of manufacturing methods, and certainly a variety of surgical and implantation procedures. Currently, surface modification methods and development of nanofiber based systems are actively being explored as areas of opportunity to retain material strength and increase biocompatibility of available meshes...
August 22, 2017: Membranes
https://www.readbyqxmd.com/read/28826804/early-wound-morbidity-after-open-ventral-hernia-repair-with-biosynthetic-or-polypropylene-mesh
#16
Sambit Sahoo, Ivy N Haskins, Li-Ching Huang, David M Krpata, Kathleen A Derwin, Benjamin K Poulose, Michael J Rosen
BACKGROUND: Recently introduced slow-resorbing biosynthetic and non-resorbing macroporous polypropylene meshes are being used in hernias with clean-contaminated and contaminated wounds. However, information about the use of biosynthetic meshes and their outcomes compared with polypropylene meshes in clean-contaminated and contaminated cases is lacking. Here we evaluate the use of biosynthetic mesh and polypropylene mesh in elective open ventral hernia repair (OVHR) and investigate differences in early wound morbidity after OVHR within clean-contaminated and contaminated cases...
August 4, 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/28822400/open-retromuscular-repair-of-parastomal-hernias-with-synthetic-mesh
#17
Lucas R Beffa, Jeremy A Warren, William S Cobb, Bryan Knoedler, Joseph A Ewing, Alfredo M Carbonell
Parastomal hernias (PHs) cause significant morbidity in patients with permanent ostomies, and several laparoscopic and open repair techniques have been described. We report our experience with open retromuscular repair of PHs using permanent synthetic mesh. A prospectively maintained database was retrospectively reviewed to identify patients undergoing PH repair. Primary outcomes are surgical site occurrence, surgical site infection (SSI), and hernia recurrence. Variables were analyzed using Pearson's χ2 test or Fisher's exact test...
August 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28822396/an-evaluation-of-parastomal-hernia-repair-using-the-americas-hernia-society-quality-collaborative
#18
MULTICENTER STUDY
Sarah S Fox, Randy Janczyk, Jeremy A Warren, Alfredo M Carbonell, Benjamin K Poulose, Michael J Rosen, William W Hope
The purpose of this review was to evaluate outcomes relating to parastomal hernia repair. Data from the Americas Hernia Society Quality Collaborative were used to identify patients undergoing parastomal hernia repair from 2013 to 2016. Parastomal hernia repairs were compared with other repairs using Pearson's test and Wilcoxon test with a P value <0.05 considered significant. Parastomal hernia repairs were performed in 311 patients. Techniques of repair include open in 85 per cent and laparoscopic in 15 per cent...
August 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28811798/an-experience-with-mesh-versus-darn-repair-in-inguinal-hernias
#19
Gulshan Ali Memon, Syed Kashif Ali Shah, Habib-Ur-Rehman
BACKGROUND & OBJECTIVE: The inguinal hernia accounts for 50 percent in old age males. A Lichtenstein type of operation has now become the method of choice in most developed countries but in the developing world traditional simple suture repair is still in common practice in resource limited hospitals due to the scarcity and expensive nature of the commercial prosthetic mesh. Our objective was to compare the rates of complications in Lichtenstein repair to tension free Darn repair. METHODS: Ninety two male patients from 20-60 years of age reported for direct or indirect inguinal hernia with open Mesh/Lichtenstein or darn repair in emergency or electively from January 2014 to December 2015 were enrolled in this prospective randomized control trial (RCT)...
May 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28808960/the-application-of-humanized-mouse-models-for-the-study-of-human-exclusive-viruses
#20
Fatemeh Vahedi, Elizabeth C Giles, Ali A Ashkar
The symbiosis between humans and viruses has allowed human tropic pathogens to evolve intricate means of modulating the human immune response to ensure its survival among the human population. In doing so, these viruses have developed profound mechanisms that mesh closely with our human biology. The establishment of this intimate relationship has created a species-specific barrier to infection, restricting the virus-associated pathologies to humans. This specificity diminishes the utility of traditional animal models...
2017: Methods in Molecular Biology
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