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https://www.readbyqxmd.com/read/29054345/the-effect-of-formal-robotic-residency-training-on-the-adoption-of-minimally-invasive-surgery-by-young-colorectal-surgeons
#1
David E Disbrow, Stephanie M Pannell, Beth-Ann Shanker, Jeremy Albright, Juan Wu, Amir Bastawrous, Mark Soliman, Jane Ferraro, Robert K Cleary
OBJECTIVE: The minimally invasive approach to colorectal surgery is still underused. Only 50% to 60% of colectomies and 10% to 20% of rectal resections for cancer are performed laparoscopically. The increasing adoption of the robotic platform for colorectal surgery warrants re-evaluation of minimally invasive surgery (MIS) training techniques. Although considering lessons learned from past laparoscopic training, a standardized national robotic training program for colon and rectal surgery residents was developed and implemented in 2011...
October 17, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/29050007/comparison-of-safety-and-efficacy-of-tacrolimus-versus-infliximab-for-active-ulcerative-colitis
#2
Ken Takeuchi, Takahiro Shimoyama, Takayuki Yamamoto
BACKGROUND: This narrative review was to determine which medication, tacrolimus (TAC) or infliximab (IFX), is safer and more effective in the management of active UC. Our literature search identified 5 studies directly comparing the outcomes of TAC versus IFX for active UC. A review of the 5 studies was undertaken. SUMMARY: The incidence of serious adverse events was not significantly different between the TAC and IFX groups. The short-term clinical remission and response rates and the colectomy-free rates were similar between the groups...
October 19, 2017: Digestive Diseases
https://www.readbyqxmd.com/read/29049425/comparison-of-internal-medicine-and-general-surgery-residents-assessments-of-risk-of-postsurgical-complications-in-surgically-complex-patients
#3
James M Healy, Kimberly A Davis, Kevin Y Pei
Importance: Anticipating postsurgical complications is a vital physician skill, particularly when counseling surgically complex patients on their risks of intervention. Although internists and surgeons both counsel patients on surgical risks, it is uncertain who is better equipped to accurately anticipate surgical complications. Objective: To examine how internal medicine and general surgery trainees compare in their assessment of risk of surgically complex patients...
October 11, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/29049081/mentor-tutoring-an-efficient-method-for-teaching-laparoscopic-colorectal-surgical-skills-in-a-general-hospital
#4
Nobuki Ichikawa, Shigenori Homma, Tadashi Yoshida, Yosuke Ohno, Hideki Kawamura, Kazuki Wakizaka, Kazuaki Nakanishi, Keizo Kazui, Hiroaki Iijima, Hiroki Shomura, Tohru Funakoshi, Shiro Nakano, Akinobu Taketomi
OBJECTIVE: We retrospectively assessed the efficacy of our mentor tutoring system for teaching laparoscopic colorectal surgical skills in a general hospital. MATERIALS AND METHODS: A series of 55 laparoscopic colectomies performed by 1 trainee were evaluated. Next, the learning curves for high anterior resection performed by the trainee (n=20) were compared with those of a self-trained surgeon (n=19). RESULTS: Cumulative sum analysis and multivariate regression analyses showed that 38 completed cases were needed to reduce the operative time...
October 18, 2017: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/29047391/report-of-a-case-combining%C3%A2-solitary-peutz-jeghers-polyp-colitis-cystica-profunda-and-high-grade-dysplasia-of-the-epithelium%C3%A2-of-the-colon
#5
Alexandros Papalampros, Michail G Vailas, Maria Sotiropoulou, Efstratia Baili, Spiridon Davakis, Demetrios Moris, Evangelos Felekouras, Ioanna Deladetsima
BACKGROUND: Colitis cystica profunda is a rare nonneoplastic disease defined by the presence of intramural cysts that contain mucus, usually situated in the rectosigmoid area, which can mimic various malignant lesions and polyps. Its etiology still remains not fully elucidated, and several mechanisms such as congenital, post-traumatic, and infectious have been implicated in the development of this rare entity. CASE PRESENTATION: Herein, we describe a unique case of colitis cystica profunda in the setting of Peutz-Jeghers-type polyp of the sigmoid colon, associated with high-grade dysplasia of the overlying epithelium in a 48-year-old female patient, who presented to the emergency room with signs of intestinal obstruction...
October 18, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29045560/inflammatory-gastrointestinal-diseases-associated-with-pd-1-blockade-antibodies
#6
M Collins, Jm Michot, Fx Danlos, C Mussini, E Soularue, C Mateus, D Loirat, A Buisson, I Rosa, O Lambotte, S Laghouati, N Chaput, C Coutzac, Al Voisin, Jc Soria, A Marabelle, S Champiat, C Robert, F Carbonnel
Background: Immune check-point blockade agents have shown clinical activity in cancer patients but are associated with immune-related adverse events that could limit their development. The aim of this study was to describe the gastrointestinal immune-related adverse events (GI-irAE) in patients with cancer treated with anti-PD-1. Methods: this is a retrospective study of consecutive adult patients who had a suspected GI-irAE due to anti-PD-1 antibodies between 2013 and 2016...
October 3, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/29045025/do-pre-operative-oral-antibiotics-increase-clostridium-difficile-infection-rates-an-analysis-of-13-959-colectomy-patients
#7
Muralidharan Parthasarathy, David Bowers, Thomas Groot-Wassink
AIM: The aim of this study was to determine whether or not preoperative oral antibiotic preparation (POAP) increases the rate of Clostridium difficile colitis (CDC) in patients undergoing colectomy. METHOD: In 2015, data for colectomies had been collected prospectively and recorded in the targeted colectomy option of the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP). This was available for retrospective analysis. Data available for analysis included elective and emergency status, POAP, surgical approach, primary anastomosis and CDC status...
October 16, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/29043596/short-term-prospective-questionnaire-study-of-early-postoperative-quality-of-life-after-colorectal-endoscopic-submucosal-dissection
#8
Fumihiko Nakamura, Yutaka Saito, Shin Haruyama, Masau Sekiguchi, Masayoshi Yamada, Taku Sakamoto, Takeshi Nakajima, Seiichiro Yamamoto, Yoshitaka Murakami, Hideki Ishikawa, Takahisa Matsuda
BACKGROUND: Endoscopic submucosal dissection (ESD) has become popular as an alternative to laparoscopy-assisted colectomy (LAC) for early colorectal cancer. AIM: To validate postoperative quality of life (QOL) based on subjective symptoms of patients from questionnaire survey. METHODS: We prospectively enrolled patients planned to undergo ESD for adenoma or Tis/T1a cancer at our institution between December 2011 and January 2013. Controls were prospectively enrolled LAC patients diagnosed with T1b cancer...
October 17, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29042709/derivation-and-basic-characterization-of-colorectal-carcinoma-primary-cell-lines
#9
Lukas Krbal, Jiri Soukup, Stanislav John, Veronika Hanusova
BACKGROUND: Colorectal carcinoma is one of the most common malignancies in western countries. Among different approaches to its research, primary cancer cell lines can play an important role. AIM: The main purposes of this study were: 1) to establish an effective and reproducible method of colorectal cancer cell isolation and cultivation from primary tumours and lymph node metastases and 2) to elucidate the biological features of the tumours favouring successful cell cultivation...
October 17, 2017: Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia
https://www.readbyqxmd.com/read/29034042/description-of-the-surgical-strategy-used-for-the-treatment-of-a-complex-disease-report-of-a-case
#10
Kazuki Kihara, Miwa Tashiro, Kohei Miyashita, Masaki Yamamoto, Hironobu Hirose, Takashi Fukutomi, Hideaki Nishimori, Kazumasa Orihashi
We report a rare case in which a patient required three surgeries with competing priorities. In a 68-year-old man diagnosed with an abdominal aortic aneurysm (AAA), computed tomography (CT) revealed an infrarenal AAA, unusual thickening of the sigmoid colon that suggested cancer, and a filling defect in the left atrium. We considered the disease stage, which affects prognosis, and the risk of complications that could interfere with the treatment of the other pathologies and developed a three-stage surgical strategy: (i) endovascular aortic repair, (ii) sigmoid colectomy, and (iii) resection of the left atrial mass...
June 25, 2017: Annals of Vascular Diseases
https://www.readbyqxmd.com/read/29033223/who-gets-a-pouch-after-colectomy-in-new-york-state-and-why
#11
Christopher T Aquina, Fergal J Fleming, Adan Z Becerra, Bradley J Hensley, Katia Noyes, John R T Monson, Larissa K Temple, Christina Cellini
BACKGROUND: This study identified variation and factors associated with ileal pouch-anal anastomosis after total colectomy for ulcerative colitis. METHODS: The Statewide Planning & Research Cooperative System was used to identify patients with ulcerative colitis who underwent total colectomy in New York state from 2000-2013. Bivariate and mixed-effects multivariable analyses were performed to assess patient, surgeon, and hospital-level factors as well as surgeon and hospital-level variation associated with ileal pouch-anal anastomosis after total colectomy...
October 12, 2017: Surgery
https://www.readbyqxmd.com/read/29032159/comparison-between-different-approaches-applied-in-laparoscopic-right-hemi-colectomy-a-systematic-review-and-network-meta-analysis
#12
REVIEW
Fei Li, Xin Zhou, Bingyan Wang, Lei Guo, Jilian Wang, Wendong Wang, Wei Fu
AIM: Several different operative approaches have been applied nowadays in laparoscopic right hemi-colectomy. This study aims to evaluate the potential benefits of different approaches by conducting a network meta-analysis (NMA). METHOD: A comprehensive literature research of the PubMed, Embase, Medline, the Cochrane Central Library, Wan Fang and China National Knowledge Infrastructure (CNKI) databases was performed. Original articles comparing two of three different approaches including medial to lateral (MtL) approach, lateral to medial (LtM) approach and cranial to caudal (CtC) approach of laparoscopic right colon resection for patients with both neoplastic and benign diseases were included...
October 12, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/29029152/surgical-treatment-in-childhood-onset-inflammatory-bowel-disease-a-nationwide-register-based-study-of-4-695-incident-patients-in-sweden-2002-2014
#13
Caroline Nordenvall, Oda Rosvall, Matteo Bottai, Åsa H Everhov, Petter Malmborg, Karin E Smedby, Anders Ekbom, Johan Askling, Jonas F Ludvigsson, Pär Myrelid, Ola Olén
Background and Aims: The incidence of childhood-onset (<18 years) inflammatory bowel disease is increasing worldwide, and some studies suggest that it represents a more severe disease phenotype. Few nationwide, population-based studies have evaluated the surgical burden in patients with childhood-onset IBD, and whether the improved medical treatment has influenced the need for gastrointestinal surgery. The aim was to examine whether the surgical treatment at any age of patients with childhood-onset IBD has changed over time...
September 27, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/29023888/editorial-do-thiopurines-and-biologics-decrease-the-risk-of-colectomy-authors-reply
#14
EDITORIAL
C Eriksson, Y Cao, S Rundquist, Y Zhulina, I Henriksson, S Montgomery, J Halfvarson
No abstract text is available yet for this article.
November 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29023884/editorial-do-thiopurines-and-biologics-decrease-the-risk-of-colectomy
#15
EDITORIAL
K H Allin, T Jess
No abstract text is available yet for this article.
November 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29020255/mini-fecal-microbiota-transplantation-mini-fmt-for-treatment-of-clostridium-difficile-proctitis-following-total-colectomy
#16
Robert Orenstein, Kara King, Roberto L Patron, John K DiBaise, David Etzioni
Rarely, in fulminant Clostridium difficile infection, the rectal stump is persistently infected following total abdominal colectomy. We report cure of a septic patient with proctitis by fecal microbiota transplant via rectal swabs (mini-FMT). This novel procedure offers a management option for recurrent CDI following total abdominal colectomy.
August 17, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29019857/interleukin-27-is-a-potential-rescue-therapy-for-acute-severe-colitis-through-interleukin-10-dependent-t-cell-independent-attenuation-of-colonic-mucosal-innate-immune-responses
#17
Mairi H McLean, Caroline Andrews, Miranda L Hanson, Walter A Baseler, Miriam R Anver, Emilee Senkevitch, Aleksandra K Staniszewska, Christopher Smith, Luke C Davies, Julie Hixon, Wenqeng Li, Wei Shen, Lothar Steidler, Scott K Durum
BACKGROUND: If treatment with intravenous steroids fail, inflammatory bowel disease patients with acute severe colitis face systemic anti-tumor necrosis factor biologic rescue therapy or colectomy. Interleukin (IL)-27 is a cytokine with an immunosuppressive role in adaptive immune responses. However, the IL-27 receptor complex is also expressed on innate immune cells, and there is evidence that IL-27 can impact the function of innate cell subsets, although this particular functionality in vivo is not understood...
November 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29019577/influence-of-the-colon-in-liver-regeneration-of-rats-submitted-to-hepatectomy-and-colectomy
#18
Marília Carvalho Moreira, Ítalo Medeiros Azevedo, Cláudia Nunes Oliveira, Aldo da Cunha Medeiros
OBJECTIVE: to evaluate whether colectomy, associated with 70% hepatectomy, influences liver regeneration in rats. METHODS: we distributed 18 Wistar rats in three groups of six animals each. In group I (sham), we performed laparotomy; In group II, colectomy + 70% hepatectomy; In group III, only 70% hepatectomy. On the 6th postoperative day, we collected blood by cardiac puncture under anesthesia, followed by euthanasia. We performed serum dosages of aspartate aminotransferase (AST), alanine aminotransferase (ALT), albumin and alkaline phosphatase (AF), hepatocyte growth factor (HGF) and transforming growth factor-α (TGF-α)...
September 2017: Revista do Colégio Brasileiro de Cirurgiões
https://www.readbyqxmd.com/read/29019111/institutional-experience-with-ostomies-created-during-cytoreductive-surgery-and-hyperthermic-intraperitoneal-chemoperfusion
#19
Sam Pakraftar, Lekshmi Ramalingam, Yongli Shuai, Heather L Jones, James F Pingpank, Steven S Ahrendt, Matthew P Holtzman, Amer H Zureikat, Herbert J Zeh, David L Bartlett, Haroon A Choudry
BACKGROUND: Cytoreductive surgery and hyperthermic intraperitoneal chemoperfusion (CRS-HIPEC) is a complex procedure that often requires ostomy creation to protect high-risk anastomoses. This study aimed to evaluate the authors' institutional experience with CRS-HIPEC-associated ostomies, determine predictors of ostomy creation and reversal, and assess their impact on survival. METHODS: The study analyzed clinicopathologic, perioperative, and oncologic data from a prospective database of 1435 CRS-HIPEC procedures for peritoneal metastases...
October 10, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29018814/the-impact-of-frailty-on-morbidity-and-mortality-following-open-emergent-colectomies
#20
Dominick V Congiusta, Prashanth Palvannan, Aziz M Merchant
BACKGROUND: Elderly and frail patients undergo open emergency colectomies and are at greater risk for complications. The relationship between frailty and open emergent colectomies is yet unexplored. OBJECTIVE: The purpose of this study was to evaluate the relationship between frailty and outcomes after open emergent colorectal surgery. DESIGN: Using the American College of Surgeons National Quality Improvement Program database, a validated modified frailty index was used, along with logistic regression, to assess the relationship between frailty and outcomes...
2017: BioMed Research International
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