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https://www.readbyqxmd.com/read/29677001/impact-of-intravenous-acetaminophen-on-perioperative-opioid-utilization-and-outcomes-in-open-colectomies-a-claims-database-analysis
#1
Isaac Wasserman, Jashvant Poeran, Nicole Zubizarreta, Jason Babby, Stelian Serban, Andrew T Goldberg, Alexander J Greenstein, Stavros G Memtsoudis, Madhu Mazumdar, Andrew B Leibowitz
BACKGROUND: The value of intravenous acetaminophen in postoperative pain management remains debated. The authors tested the hypothesis that intravenous acetaminophen use, in isolation and in comparison to oral, would be associated with decreased opioid utilization (clinically significant reduction defined as 25%) and opioid-related adverse effects in open colectomy patients. METHODS: Using national claims data from open colectomy patients (Premier Healthcare Database, Premier Healthcare Solutions, Inc...
April 20, 2018: Anesthesiology
https://www.readbyqxmd.com/read/29674758/evaluation-of-the-upper-gastrointestinal-tract-in-ulcerative-colitis-patients
#2
Ryo Kato, Masaya Iwamuro, Sakiko Hiraoka, Shiho Takashima, Toshihiro Inokuchi, Masahiro Takahara, Yoshitaka Kondo, Takehiro Tanaka, Hiroyuki Okada
To analyze the clinical characteristics of patients with ulcerative colitis who have upper gastrointestinal lesions, we retrospectively reviewed the data of 216 patients with ulcerative colitis who underwent esophagogastroduodenoscopy at our institute in April 2008-March 2016. We investigated the endoscopic features and compared the clinical characteristics between the patients with and without upper gastrointestinal lesions. Forty-two patients (19.4%) had upper gastrointestinal lesions, including multiple erosions (n=18), bamboo joint-like appearance (n=17), mucosa with white spots (n=4), friable mucosa (n=2), ulcer (n=1), and purulent deposits within the mucosa (n=1) in the stomach and/or duodenum...
April 2018: Acta Medica Okayama
https://www.readbyqxmd.com/read/29668982/improved-medical-treatment-and-surgical-surveillance-of-children-and-adolescents-with-ulcerative-colitis-in-the-united-kingdom
#3
Marcus Karl-Keinz Auth, Su K Bunn, Aimee Leanne Protheroe, Linda Jane Williams, John M Fell, Rafeeq Muhammed, Nicholas Michael Croft, R Mark Beattie, Anne Willmott, Christine Spray, Babu Vadamalayan, Astor Rodrigues, John Puntis, Anna Jane Pigott, David C Wilson, Sally Mitton, Mark Furman, Charlie Charlton, Sonny K F Chong, Richard K Russell
Background: Pediatric ulcerative colitis (UC) presents at an earlier age and increasing prevalence. Our aim was to examine morbidity, steroid sparing strategies, and surgical outcome in children with active UC. Methods: A national prospective audit was conducted for the inpatient period of all children with UC for medical or surgical treatment in the United Kingdom (UK) over 1 year. Thirty-two participating centers recruited 224 children in 298 admissions, comparisons over 6 years were made with previous audits...
April 13, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29668968/outcomes-of-endoscopic-resections-of-large-laterally-spreading-colorectal-lesions-in-inflammatory-bowel-disease-a-single-united-kingdom-center-experience
#4
Shraddha Gulati, Andrew Emmanuel, Margaret Burt, Patrick Dubois, Bu'Hussain Hayee, Amyn Haji
Background: The SCENIC consensus statement recommends endoscopic resection of all visible dysplasia in inflammatory bowel disease, but patients with large or complex lesions may still be advised to have colectomy. This article presents outcomes for large nonpolypoid resections associated with colitis at our institution. Methods: Data including demographics, clinical history, lesion characteristics, method of resection, and postresection surveillance were collected prospectively in patients with visible lesions within colitic mucosa from January 2011 to November 2016...
April 13, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29668948/combined-infection-of-human-herpes-viruses-a-risk-factor-for-subsequent-colectomy-in-ulcerative-colitis
#5
Shuhei Hosomi, Kenji Watanabe, Yu Nishida, Hirokazu Yamagami, Tomomi Yukawa, Koji Otani, Yasuaki Nagami, Fumio Tanaka, Koichi Taira, Noriko Kamata, Tetsuya Tanigawa, Masatsugu Shiba, Toshio Watanabe, Hisashi Nagahara, Kiyoshi Maeda, Yasuhiro Fujiwara
Background: Little is known about the prevalence and pathogenicity of human herpes viruses except for cytomegalovirus (CMV) in patients with inflammatory bowel disease (IBD). The aim of this study was to determine the prevalence of human herpes viruses on colonic mucosa in patients with IBD and assess the long-term outcomes in these patients. Methods: We examined the colonic mucosal specimens from 66 patients with ulcerative colitis (UC), 54 patients with Crohn's disease (CD), and 29 healthy patients to identify the 6 most common types of human herpes virus, using multiplex polymerase chain reaction (PCR) technique...
April 13, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29668929/chromoendoscopy-for-dysplasia-surveillance-in-inflammatory-bowel-disease
#6
Ann D Flynn, John F Valentine
Long-standing ulcerative colitis (UC) and extensive Crohn's colitis confer increased risk for development of colorectal cancer. Screening and surveillance colonoscopy programs aim to identify, resect, or detect dysplasia or colorectal cancer. Dysplastic lesions can be removed by endoscopic resection and patients with unresectable lesions can be referred for colectomy at an earlier stage, with the goal of reducing overall morbidity and mortality from colorectal cancer. Surveillance colonoscopy for patients with inflammatory bowel disease (IBD) is endorsed by multiple specialty societies...
April 13, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29668897/dysplasia-in-inflammatory-bowel-disease-historical-review-critical-histopathological-analysis-and-clinical-implications
#7
Anders Mark-Christensen, Søren Laurberg, Najib Haboubi
Colorectal cancer is the most serious complication of chronic inflammatory bowel disease. It is generally accepted that dysplasia in most cases precedes the development of colorectal cancer. Thus, detection of dysplasia through surveillance may allow therapeutic interventions to lower the risk of cancer. Our understanding of dysplasia has evolved over the past decades and guided rational decision-making, but many questions remain unanswered. We are currently at the brink of a new era, where new avenues in the endoscopic detection and management of dysplasia are pursued, and the paradigm of a colectomy being the preferred treatment for advanced neoplasia is changing...
April 13, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29666000/how-does-the-application-of-surgical-components-in-enhanced-recovery-programs-for-colorectal-surgery-change-over-time
#8
Julie Veziant, Daniel Leonard, Bruno Pereira, Karem Slim
BACKGROUND: Enhanced recovery programs (ERP) improve post-operative outcomes in proportion to how fully they are implemented. Maintaining an optimal level of application of all the ER components is thus essential. Our aim was to assess the sustainability of ER surgical components 2 years after their first implementation. METHOD: Patients undergoing elective colorectal resections were included in a prospective database. To retrospectively analyze compliance with ERP over a period of 24 months, the following components were considered: colonic preparation, surgical approach, nasogastric tube omission and absence of abdominal drainage...
April 14, 2018: Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
https://www.readbyqxmd.com/read/29664889/transfer-status-a-significant-risk-factor-for-mortality-in-emergency-general-surgery-patients-requiring-colon-resection
#9
Michael P DeWane, Kimberly A Davis, Kevin M Schuster, Scott P Erwin, Adrian A Maung, Robert D Becher
BACKGROUND: Patients requiring emergency surgery have increased rates of morbidity and mortality. Transfer from outside institution delays effective control of ongoing infection and has been linked with worse outcomes. Previous research suggests transfer status negatively impacts survival but hasn't examined the effect of location and type of institution prior to transfer. This study aims to characterize the effect of type of transferring institution on postoperative outcomes after emergency colon surgery...
April 16, 2018: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29663301/laparoscopic-versus-open-colectomy-the-impact-of-frailty-on-outcomes
#10
Pankti Kothari, Dominick V Congiusta, Aziz M Merchant
Frailty in the elderly population is an important predictor of surgical outcomes. It has been quantified by several models, including the modified frailty index, which has demonstrated applicability in many surgical subspecialties. We aim to conduct the first decade-long retrospective analysis of frailty and complications between open and laparoscopic colectomy. We used the American College of Surgeons National Surgical Quality Improvement Program database to identify colectomies performed between 2005 and 2014...
April 16, 2018: Updates in Surgery
https://www.readbyqxmd.com/read/29662931/ulcerative-colitis-are-we-neglecting-its-progressive-character
#11
Paulo Massinha, Francisco Portela, Sara Campos, Gabriela Duque, Manuela Ferreira, Sofia Mendes, Ana Margarida Ferreira, Carlos Sofia, Luís Tomé
Introduction: Ulcerative colitis (UC) is a chronic disease but its progressive character, with structural damage, is insufficiently studied. Objectives: To analyze a group of patients without referral bias, regarding its clinical course, the morphological damage, and functional status. Methods: We evaluated UC patients diagnosed between January 1, 2000 and December 31, 2004, living in the direct referral area of the hospital and determined the medication use, colectomy rate, structural damage ("lead pipe," stenosis, pseudopolyps, fibrous bridges), and anorectal function (prospective evaluation with the Cleveland Clinic Incontinence Score [CCIS] and the Fecal Incontinence Quality of Life Scale)...
March 2018: GE Portuguese Journal of Gastroenterology
https://www.readbyqxmd.com/read/29661276/postoperative-morbidity-and-mortality-for-malignant-colon-obstruction-the-american-college-of-surgeon-calculator-reliability
#12
Maxime K Collard, David Moszkowicz, Anne-Caroline Clause-Verdreau, Alain Beauchet, Tristan Cudennec, Karina Vychnevskaia, Robert Malafosse, Frédérique Peschaud
BACKGROUND: The American College of surgical risk calculator (SRC) score has never been validated specifically for surgery in emergency. The objective was to evaluate the reliability of this calculator in patients with malignant colon obstruction. MATERIALS AND METHODS: We retrospectively have analyzed the morbidity and mortality observed in operated patients. Risk factors for postoperative morbidity and mortality were analyzed by logistic regression model. We have compared the morbidity and mortality estimated by the SRC score with that observed using the Brier Score (BS)...
June 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29658679/iatrogenic-spleen-injury-during-minimally-invasive-left-colonic-flexure-mobilization-the-quest-for-evidence-based-results
#13
Alberto Mangano, Federico Gheza, Pier C Giulianotti
INTRODUCTION: To assess the frequency, risk factors and outcomes of iatrogenic spleen injury during minimally invasive colo-rectal surgery with a particular focus on the routine splenic flexure mobilization tehcnique. EVIDENCE ACQUISITION: Exclusion criteria: 1. topic not pertinent to the main topic of the review; 2. All case reports, editorials, conference highlights were excluded. After a title and abstract first selection and a final full-text analysis has been performed...
April 13, 2018: Minerva Chirurgica
https://www.readbyqxmd.com/read/29658059/visceral-fat-area-not-body-mass-index-predicts-postoperative-30-day-morbidity-in-patients-undergoing-colon-resection-for-cancer
#14
Benjamin A Kuritzkes, Emmanouil P Pappou, Ravi P Kiran, Onur Baser, Liqiong Fan, Xiaotao Guo, Binsheng Zhao, Stuart Bentley-Hibbert
PURPOSE: Colectomy for cancer in obese patients is technically challenging and may be associated with worse outcomes. Whether visceral obesity, as measured on computed tomography, is a better predictor of complication than body mass index (BMI) or determines long-term oncologic outcomes has not been well characterized. This study examines the association between derived anthropometrics and postoperative complication and long-term oncologic outcomes. METHODS: Retrospective review of patients undergoing elective colectomy for cancer at a single tertiary-care center from 2010 to 2016...
April 15, 2018: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29657704/successful-treatment-of-three-synchronous-primary-malignant-tumours-reflection-on-surgical-pathological-and-oncological-aspects-and-decision-making
#15
Emese Irma Ágoston, Áron Somorácz, Lilla Madaras, Attila Zaránd, Gyöngyvér Szentmártoni, Zsuzsanna Orosz, Magdolna Dank, Zsolt Baranyai
We report a case of a patient with triple synchronous primary malignancies (breast, colon, kidney) which has not been previously reported in the literature. A 70-year-old woman was diagnosed with invasive ductal carcinoma of the left breast with axillary lymph node metastasis. During the staging period, renal cell carcinoma on the left kidney and mucinous adenocarcinoma in the proximal colon were found. Since the breast tumour demonstrated favourable biology, aromatase inhibitor therapy had been started and simultaneous right colectomy and left nephrectomy was performed...
April 2018: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29650941/-a-case-of-an-intraductal-papillary-mucinous-neoplasm-which-rapidly-worsened-and-penetrated-into-the-stomach-and-the-transverse-colon
#16
Akira Sogawa, Kei Nakamura, Tomoyuki Nagata, Satoshi Mochizuki, Yuen Nakase, Shozo Kitai, Seishirou Inaba, Keiji Shimada
We report a case of a 71-year-old woman.She visited our hospital with a complaint of high fever and abdominal distention. She has been pointed out intraductal papillary mucinous neoplasm(IPMN)4 years ago.Abdominal CT showed cystic legion, 80mm in diameter, on the pancreas.The lesion was unclear at the boundary between the main pancreatic duct and in contact with the stomach, transverse colon.Upper endoscopic and colonoscopic examination revealed the exhaustion image from the intestional tract but not pointed out the malignant findings...
March 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29650856/-a-case-of-performed-right-colectomy-with-pancreato-duodenectomy-for-transverse-colon-cancer-invased-to-duodenum
#17
Ryutaro Udo, Masanobu Enomoto, Kazushige Tsurui, Yuu Kuboyama, Hiroshi Kuwabara, Masatoshi Shigoka, Tetsuo Ishizaki, Kenji Katsumata, Hiyo Obikane, Akihiko Tsuchida
There is a clear consensus regarding the combined resection of organs with cancer invasion, patients with colon cancer. However, there are very few reports to our knowledge regarding the use of pancreato-duodenectomy(PD)for colon cancer patients with cancer invasion in the duodenum. We here report a colon cancer patient in whom we performed PD and right hemicolectomy, who showed favorable results with no recurrence. The patient was a 69-year-old woman. Her chief complaint was hypogastric pain. Her previous doctor performed colonoscopy and a colonoscopic biopsy, and detected a type 2 lesion, throughout the entire circumference of the transverse colon near the liver, and she was diagnosed with adenocarcinoma...
April 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29650843/-a-case-of-gastric-carcinoma-with-peritoneal-dissemination-treated-with-curative-resection-following-trastuzumab-plus-capecitabine-plus-cisplatin-combined-therapy
#18
Yusuke Matsuda, Satoshi Suzuki, Ritsuko Maehara, Yoshiko Matsuda, Shingo Kanaji, Masashi Yamamoto, Hiroshi Hasegawa, Koudai Yamashita, Takeru Matsuda, Taro Oshikiri, Yasuo Sumi, Tetsu Nakamura, Yoshihiro Kakeji
A 67-year-old man was referred to our hospital with a diagnosis of type 3 gastric cancer in lower third of the stomach. Computed tomography(CT)scan showed no distant metastasis, but peritoneal dissemination from gastric cancer. A laparoscopic exploration diagnosed pStage IV gastric cancer with peritoneal dissemination. Trastuzumab, capecitabine and cisplatin therapy was administered for initially unresectable gastric cancer. After 6courses of chemotherapy, primary lesion and lymph node metastasis shrank, and the peritoneal dissemination did not worsen by CT scan...
April 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29630003/use-of-primary-anastomosis-with-diverting-ileostomy-in-patients-with-acute-diverticulitis-requiring-urgent-operative-intervention
#19
Christy E Cauley, Ruchin Patel, Liliana Bordeianou
BACKGROUND: Previous studies suggest that urgent colectomy and primary anastomosis with diversion is safe for perforated diverticulitis. Current guidelines support this approach. OBJECTIVE: The purpose of this study was to describe the use of urgent or emergent primary anastomosis with diversion in diverticulitis before the 2014 American Society of Colon and Rectal Surgeons guidelines and compare national outcomes of primary anastomosis with diversion to the Hartmann procedure...
May 2018: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/29621034/role-of-emergency-laparoscopic-colectomy-for-colorectal-cancer-a-population-based-study-in-england
#20
Abigail E Vallance, Deborah S Keller, James Hill, Michael Braun, Angela Kuryba, Jan van der Meulen, Kate Walker, Manish Chand
OBJECTIVE: To evaluate factors associated with the use of laparoscopic surgery and the associated postoperative outcomes for urgent or emergency resection of colorectal cancer in the English National Health Service. SUMMARY OF BACKGROUND DATA: Laparoscopy is increasingly used for elective colorectal cancer surgery, but uptake has been limited in the emergency setting. METHODS: Patients recorded in the National Bowel Cancer Audit who underwent urgent or emergency colorectal cancer resection between April 2010 and March 2016 were included...
April 4, 2018: Annals of Surgery
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