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Bone cement

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https://www.readbyqxmd.com/read/29149487/fabrication-of-chelate-setting-%C3%AE-tricalcium-phosphate-cement-using-sodium-citrate-and-sodium-alginate-as-mixing-solution-and-its-in-vivo-osteoconductivity
#1
Toshiisa Konishi, Poon Nian Lim, Michiyo Honda, Masaki Nagaya, Hiroshi Nagashima, Eng San Thian, Mamoru Aizawa
Moldable and injectable calcium-phosphate cements (CPCs) are material candidates for bone replacement applications. In the present study, we examined the effectiveness of sodium alginate and sodium citrate additives to the liquid phase of CPC, in improving its handling property as well as mechanical strength. The use of these additives enhanced the handling property significantly, in terms of consistency as compared to CPC without additives due to the liquefying effect caused by the adsorption of citrate ions on the cement particles...
November 17, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/29145010/the-use-of-hardened-bone-cement-as-an-impaction-grafting-extender-for-revision-hip-arthroplasty
#2
Mark Ruddy, David P FitzPatrick, Kenneth T Stanton
Impaction bone grafting is a method of restoring bone stock to patients who have suffered significant bone loss due to revision total hip surgery. The procedure requires morsellised cancellous bone (MCB) to be impacted into the site of bone loss in order to stabilise the prosthesis with the aim of long term resorption and reintegration of the impacted bone graft. Due to financial cost and the potential to transmit disease, the use of supplementary material, known as an extender, is frequently used to increase the graft material volume...
November 13, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29138601/zinc-phosphate-as-a-definitive-cement-for-implant-supported-crowns-and-fixed-dentures
#3
Dennis Flanagan
Implant-supported dental prostheses can be retained by a screw or cement. Implant-supported fixed partial dentures have a passive fit. A passive fit means there is an internal gap between the abutment surface and the intaglio of the retainer to insure that there is no lateral pressure on the supporting implants or friction upon seating of the prosthesis. This gap is filled with cement for retention of the prosthesis. Any lateral pressure may cause marginal bone loss or periimplantitis. Also, there is usually a microscopic gap at the margin of a crown retainer that exposes the cement to oral fluids...
2017: Clinical, Cosmetic and Investigational Dentistry
https://www.readbyqxmd.com/read/29135862/management-of-sigmoid-sinus-associated-pulsatile-tinnitus-a-systematic-review-of-the-literature
#4
Alan C Wang, Avery N Nelson, Cassandra Pino, Peter F Svider, Robert S Hong, Eleanor Chan
OBJECTIVES: Although studies demonstrate 4 to 20% of patients with pulsatile tinnitus (PT) have associated sigmoid sinus anomalies, no consensus exists regarding optimal management. Our objective was to perform a systematic review exploring surgical and endovascular intervention of PT caused by sigmoid sinus anomalies. DATA SOURCES/EXTRACTION: A systematic review was performed using the Preferred Reporting Systems for Systematic Reviews and Meta-Analysis guidelines for reporting of results, with a target population encompassing patients with PT and either sigmoid sinus diverticulum or sigmoid wall dehiscence...
December 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/29134167/postoperative-imaging-findings-associated-with-transpalpebral-craniotomy-approach-to-anterior-cranial-fossa
#5
Dennis Monks, Allison Weyer, Peter Thurlow, Khaled Aziz, Erik Happ, Michael Goldberg
Background and Purpose  The transpalpebral "eyelid" approach is a novel alternative to the traditional ciliary or supraciliary incision for supraorbital frontal craniotomy and access to the anterior cranial fossa. Though a prior publication from our institution has described the surgical approach in detail along with cosmetic and clinical outcomes, postoperative imaging findings have not yet been described. As this surgical technique becomes more widely practiced, it is essential for neuroradiologists, oculoplastic surgeons, and skull base neurosurgeons to be familiar with the expected postoperative imaging findings, especially those that prompt subsequent intervention...
December 2017: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/29127887/pullout-strength-of-cement-augmented-and-wide-suture-transosseous-fixation-in-the-greater-tuberosity
#6
Brendan Y Shi, Miguel Diaz, Stephen M Belkoff, Uma Srikumaran
BACKGROUND: Obtaining strong fixation in low-density bone is increasingly critical in surgical repair of rotator cuff tears because of the aging population. To evaluate two new methods of improving pullout strength of transosseous rotator cuff repair in low-density bone, we analyzed the effects of 1) using 2-mm suture tape instead of no. 2 suture and 2) augmenting the lateral tunnel with cement. METHODS: Eleven pairs of osteopenic or osteoporotic cadaveric humeri were identified by dual-energy x-ray absorptiometry...
November 2, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/29125988/quantification-of-nitrogenous-bases-dna-and-collagen-type-i-for-the-estimation-of-the-postmortem-interval-in-bone-remains
#7
Cristina Pérez-Martínez, María D Pérez-Cárceles, Isabel Legaz, Gemma Prieto-Bonete, Aurelio Luna
Estimating the postmortem interval (PMI) is an important goal in forensic medicine and continues to be one of the most difficult tasks of the forensic investigator. Few accurate methods exist to determine the time since death of skeletonized human remains due to the great number of intrinsic and external factors that may alter the normal course of postmortem change. The purpose of this research was to assess the usefulness of various biochemical parameters, such as nitrogenous bases (adenine, guanine, purines, cytosine, thymine, pyrimidines, hypoxanthine and xanthine), DNA and Collagen Type I peptides to estimate PMI...
November 4, 2017: Forensic Science International
https://www.readbyqxmd.com/read/29122282/masquelet-technique-with-external-locking-plate-for-recalcitrant-distal-tibial-nonunion
#8
Ching-Hou Ma, Yen-Chun Chiu, Kun-Ling Tsai, Yuan-Kun Tu, Cheng-Yo Yen, Chin-Hsien Wu
OBJECTIVE: In the present retrospective study, we aimed to analyze the results of treatment for recalcitrant distal tibial nonunion using Masquelet technique with locking plate as a definitive external fixator. MATERIALS: We included 15 consecutive cases of distal tibial nonunion treated at our hospital between January 2012 and December 2015. The reconstructive procedure comprised debridement of the nonunion site, deformity correction, stabilization with an external locked plate, defect filling with cement spacer for inducing membrane formation, and bone reconstruction using a cancellous bone autograft (Masquelet technique)...
October 26, 2017: Injury
https://www.readbyqxmd.com/read/29121658/risk-factors-for-postoperative-deep-infection-in-bone-tumors
#9
Shinji Miwa, Toshiharu Shirai, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Kaoru Tada, Yoshitomo Kajino, Hiroyuki Inatani, Takashi Higuchi, Kensaku Abe, Yuta Taniguchi, Hiroyuki Tsuchiya
BACKGROUND: Postoperative deep infection after bone tumor surgery remains a serious complication. Although there are numerous reports about risk factors for postoperative deep infection in general surgery, there is only a small number of reports about those for bone tumor surgery. This retrospective study aimed to identify risk factors for postoperative deep infection after bone tumor resection. METHODS: We reviewed data of 681 patients (844 bone tumors) who underwent surgery...
2017: PloS One
https://www.readbyqxmd.com/read/29116357/injectable-biomechanically-robust-biodegradable-and-osseointegrative-bone-cement-for-percutaneous-kyphoplasty-and-vertebroplasty
#10
Huiling Liu, Bin Liu, Chunxia Gao, Bin Meng, Huilin Yang, Haiyang Yu, Lei Yang
PURPOSE: Poly(methyl methacrylate) (PMMA) cement is widely used for percutaneous kyphoplasty and vertebroplasty (PKP and PVP) but possesses formidable shortcomings due to non-degradability. Here, a biodegradable replacement is developed. METHODS: Calcium phosphate cement (CPC) was redesigned by incorporating starch and BaSO4 (new cement named as CPB). The biomechanical, biocompatibility, osseointegrative and handling properties of CPB were systematically evaluated in vitro and in vivo by the models of osteoporotic sheep vertebra, rat subcutaneous implantation and rat femoral defect...
November 7, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/29114643/analytical-evaluation-of-a-vancomycin-immunoassay-in-synovial-fluid
#11
REVIEW
Francesca Luceri, Fiamma Balboni, Giovanni Balato, Paola Pezzati, Nicoletta Cini, Gianni Virgili, Andrea Baldini
In clinical laboratories performing routine activities, the need to answer the burning clinical question in emerging field may be limited by lack of technology support or assays accessibility. Commercially available methods, although originally validated for specific biological matrices, may be employed for other matrices, following appropriate guidelines such as Clinical and Laboratory Standards Institute (CLSI) EP 19. We investigated the use of a vancomycin assay with synovial fluid samples, in view of a possible employment in vancomycin release study...
June 2017: Joints
https://www.readbyqxmd.com/read/29113568/combined-delivery-of-bone-morphogenetic-protein-2-and-insulin-like-growth-factor-1-from-nano-poly-%C3%AE-glutamic-acid-%C3%AE-tricalcium-phosphate-based-calcium-phosphate-cement-and-its-effect-on-bone-regeneration-in%C3%A2-vitro
#12
Xiulin Shu, Jin Feng, Jing Feng, Xiaomo Huang, Liangqiu Li, Qingshan Shi
In this study, nano-doped calcium phosphate cement delivery systems (poly (γ-glutamic acid)/β-tricalcium phosphate/calcium phosphate ceramics and nano (γ-glutamic acid)/β-tricalcium phosphate/calcium phosphate ceramic) were fabricated, and low doses (10 µg/g) of two growth factors, insulin-like growth factor-1 and bone morphogenetic protein-2, were encapsulated then sequentially released. We characterized the delivery systems using Fourier transform infrared spectroscopy and X-ray diffraction and measured washout resistance and compressive strength, and thus optimized the most appropriate proportioning of delivery systems for the two growth factors...
November 2017: Journal of Biomaterials Applications
https://www.readbyqxmd.com/read/29111845/pre-clinical-evaluation-of-the-mechanical-properties-of-a-low-stiffness-cement-injectable-hip-stem
#13
Ibrahim Eldesouky, Ola Harrysson, Denis J Marcellin-Little, Harvey West, Hassan El-Hofy
In total hip arthroplasty (THA), the femoral stem can be fixed with or without bone cement. Cementless stem fixation is recommended for young and active patients as it eliminates the risk of loss of fixation at the bone-cement and cement-implant interfaces. Cementless fixation, however, suffers from a relatively high early revision rate. In the current research, a novel low-stiffness hip stem was designed, fabricated and tested. The stem design provided the option to inject biodegradable bone cement that could enhance initial stem stability...
November 7, 2017: Journal of Medical Engineering & Technology
https://www.readbyqxmd.com/read/29110910/treatment-of-giant-cell-tumor-of-distal-radius-with-limited-soft-tissue-invasion-curettage-and-cementing-versus-wide-excision
#14
Kamran Mozaffarian, Mehra Modjallal, Amir Reza Vosoughi
BACKGROUND: Intralesional curettage and adjuvant versus wide en bloc excision (WEE) as the best treatment method of giant cell tumor (GCT) of distal radius with limited soft tissue extension is a controversial topic. METHODS: Prospectively, 13 patients who had GCT of distal radius with perforation of either volar or dorsal cortex of the bone and soft tissue extension which was confined to one plane were enrolled in the study. Six patients treated with ICC and seven cases cured by WEE technique and proximal fibular arthroplasty...
October 27, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/29107056/strontium-modified-premixed-calcium-phosphate-cements-for-the-therapy-of-osteoporotic-bone-defects
#15
A Lode, C Heiss, G Knapp, J Thomas, B Nies, M Gelinsky, M Schumacher
In this study a premixed strontium-containing calcium phosphate bone cement for the application in osteoporotic bone defects has been developed and characterised regarding its material and in vitro properties as well as minimally invasive applicability in balloon kyphoplasty. Strontium was introduced into the cement by substitution of one precursor component, CaCO3, with its strontium analogue, SrCO3. Using a biocompatible oil phase as carrier liquid, a cement paste that only set upon contact with aqueous environment was obtained...
October 26, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/29105970/effects-of-platelet-rich-plasma-on-biological-activity-and-bone-regeneration-of-brushite-based-calcium-phosphate-cement
#16
Md Lemon Hasan, Mirana Taz, Byong-Taek Lee
In this study, we focused on identifying the effects of platelet-rich plasma (PRP) on bioactivity and bone ingrowths incorporated into brushite cement. We introduced PRP as a series of substitutions with an aqueous citrate-ion solution, and the optimized cement with PRP showed no disintegration of the paste consistency. Incorporating PRP showed that the setting time decreased with the increasing of PRP ratios, although the compressive strength was not significantly changed. We evaluated in vitro degradation and bioactivity with the simulated body fluid test, and the result showed that adding PRP accelerated the carbonated apatite nucleation and markedly improved the surface reactivity of the cement...
November 6, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/29105568/the-mechanical-response-of-a-polyetheretherketone-femoral-knee-implant-under-a-deep-squatting-loading-condition
#17
Lennert de Ruiter, Dennis Janssen, Adam Briscoe, Nico Verdonschot
The current study was designed to investigate the mechanical response of a polyetheretherketone-on-polyethylene total knee replacement device during a deep squat. Application of this high-demand loading condition can identify weaknesses of the polyetheretherketone relative to cobalt-chromium. This study investigated whether the implant is strong enough for this type of loading, whether cement stresses are considerably changed and whether a polyetheretherketone femoral component is likely to lead to reduced periprosthetic bone loss as compared to a cobalt-chromium component...
November 1, 2017: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/29105532/early-aseptic-loosening-of-a-mobile-bearing-total-knee-replacement
#18
Ines Kutzner, Geir Hallan, Paul Johan Høl, Ove Furnes, Øystein Gøthesen, Wender Figved, Peter Ellison
Background and purpose - Registry-based studies have reported an increased risk of aseptic tibial loosening for the cemented Low Contact Stress (LCS) total knee replacement compared with other cemented designs; however, the reasons for this have not been established. We made a retrieval analysis with the aim of identifying the failure mechanism. Patients and methods - We collected implants, cement, tissue, blood, and radiographs from 32 failed LCS Complete cases. Damage to the tibial baseplate and insert was assessed...
November 6, 2017: Acta Orthopaedica
https://www.readbyqxmd.com/read/29104084/orthopaedic-implant-materials-drive-m1-macrophage-polarization-in-a-spleen-tyrosine-kinase-and-mitogen-activated-protein-kinase-dependent-manner
#19
Olwyn R Mahon, Sarah O'Hanlon, Clare C Cunningham, Geraldine M McCarthy, Christopher Hobbs, Valeria Nicolosi, Daniel J Kelly, Aisling Dunne
Total joint replacements (TJR) are costly procedures required to relieve pain and restore function in patients suffering from end-stage arthritis. Despite great progress in the development and durability of TJRs, the generation of prosthesis-associated wear particles over time leads to an inflammatory cascade which culminates in periprosthetic osteolysis. Studies suggest that wear particles drive the polarization/differentiation of immature macrophages towards a pro-inflammatory M1 phenotype rather than an anti-inflammatory M2 phenotype associated with normal bone and wound healing...
November 2, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/29103064/risk-factors-associated-with-adjacent-vertebral-compression-fracture-following-percutaneous-vertebroplasty-after-menopause-a-retrospective-study
#20
Hua Li, Da-Long Yang, Lei Ma, Hui Wang, Wen-Yuan Ding, Si-Dong Yang
BACKGROUND Clinically, percutaneous vertebroplasty (PVP) is frequently applied to treat osteoporotic vertebral compression fracture (OVCF). It is believed that new compression fractures are more likely to occur adjacent to the PVP-treated segment, typically within 1 month after PVP. The purpose of this study was to investigate risk factors for adjacent vertebral compression fractures (AVCF) after PVP in patients with OVCF after menopause. MATERIAL AND METHODS Between Jun 2012 and Dec 2016, 412 patients were initially identified...
November 5, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
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