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https://www.readbyqxmd.com/read/28916911/evaluation-of-thirty-eight-cemented-pegged-glenoid-components-with-variable-backside-curvature-two-year-minimum-follow-up
#1
Florence Dauzère, Marine Arboucalot, Julie Lebon, Fanny Elia, Nicolas Bonnevialle, Pierre Mansat
BACKGROUND: The PERFORM™ pegged glenoid system has been used for shoulder arthroplasty since 2012. This system offers multiple backside curvatures per size to better match variable patient anatomy. As a result, less reaming is required and subchondral bone is preserved-a critical factor in preventing glenoid migration and loosening, thus enhancing implant longevity. PURPOSE: The purpose of this study was to analyze all radiographic modifications around this new glenoid implant...
September 15, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28916883/different-post-processing-conditions-for-3d-bioprinted-%C3%AE-tricalcium-phosphate-scaffolds
#2
Liciane Sabadin Bertol, Rodrigo Schabbach, Luis Alberto Loureiro Dos Santos
The development of 3D printing hardware, software and materials has enabled the production of bone substitute scaffolds for tissue engineering. Calcium phosphates cements, such as those based on α-tricalcium phosphate (α-TCP), have recognized properties of osteoinductivity, osteoconductivity and resorbability and can be used to 3D print scaffolds to support and induce tissue formation and be replaced by natural bone. At present, however, the mechanical properties found for 3D printed bone scaffolds are only satisfactory for non-load bearing applications...
September 15, 2017: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/28913412/addition-of-wollastonite-fibers-to-calcium-phosphate-cement-increases-cell-viability-and-stimulates-differentiation-of-osteoblast-like-cells
#3
Juliana Almeida Domingues, Mariana Motisuke, Celso Aparecido Bertran, Moema A Hausen, Eliana Aparecida de Rezende Duek, José Angelo Camilli
Calcium phosphate cement (CPC) that is based on α-tricalcium phosphate (α-TCP) is considered desirable for bone tissue engineering because of its relatively rapid degradation properties. However, such cement is relatively weak, restricting its use to areas of low mechanical stress. Wollastonite fibers (WF) have been used to improve the mechanical strength of biomaterials. However, the biological properties of WF remain poorly understood. Here, we tested the response of osteoblast-like cells to being cultured on CPC reinforced with 5% of WF (CPC-WF)...
2017: TheScientificWorldJournal
https://www.readbyqxmd.com/read/28895428/decreased-migration-with-locally-administered-bisphosphonate-in-cemented-cup-revisions-using-impaction-bone-grafting-technique
#4
Vasileios Zampelis, Ola Belfrage, Magnus Tägil, Martin Sundberg, Gunnar Flivik
Background and purpose - Impaction bone grafting (IBG) in revision hip surgery is an established method in restoring bone stock deficiencies. We hypothesized that local treatment of the morsellized allograft with a bisphosphonate in cemented revision would, in addition to increased bone density, also reduce the early migration of the cup as measured by radiostereometry (RSA). Patients and methods - 20 patients with aseptic cup loosening underwent revision using the IBG technique. The patients were randomized to either clodronate (10 patients) or saline (10 patients, control group) as local adjunct to the morsellized bone...
September 12, 2017: Acta Orthopaedica
https://www.readbyqxmd.com/read/28894615/chronic-osteomyelitis-of-the-distal-femur-treated-with-resection-and-delayed-endoprosthetic-reconstruction-a-report-of-three-cases
#5
Sean Ryan, William Eward, Brian Brigman, Robert Zura
Chronic osteomyelitis involving the distal femur often results in amputation or arthrodesis. This article presents three cases of chronic osteomyelitis treated with a staged approach culminating in endoprosthetic reconstruction. Stage one involved resection of infected bone and placement of an intramedullary nail spanning the bony defect between proximal femur and tibia, with antibiotic cement packed around the nail. Patients were then placed on long-term IV +/- oral antibiotics to clear the infection. A "cooldown" period was then used between stages where patients were off antibiotics and inflammatory markers were monitored for signs of remaining infection...
2017: Case Reports in Orthopedics
https://www.readbyqxmd.com/read/28891873/hearing-outcome-with-the-use-of-glass-ionomer-cement-as-an-alternative-to-crimping-in-stapedotomy
#6
Saad Elzayat, Ahmed Younes, Ayman Fouad, Fatthe Erfan, Ali Mahrous
OBJECTIVE: To evaluate early hearing outcomes using glass ionomer cement to fix the Teflon piston prosthesis onto the long process of incus to minimize residual conductive hearing loss after stapedotomy. STUDY DESIGN: Original report of prospective randomized control study. SETTING: Tertiary referral center. PATIENTS: A total of 80 consecutive patients with otosclerosis were randomized into two groups. Group A is a control group in which 40 patients underwent small fenestra stapedotomy using the classic technique...
October 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28888007/nano%C3%A2-calcium-phosphate-bone-cement-based-on-si-stabilized-%C3%AE-tricalcium-phosphate-with-improved-mechanical-properties
#7
M Roozbahani, M Alehosseini, M Kharaziha, R Emadi
This study aimed to develop nano‑calcium phosphate cement (nCPC) and evaluate the effect of nanosized precursors on mechanical, physical and handling properties (injectability and setting time) as well as conversion rate of nano-reactants into nano-hydroxyapatite (nHA). In this study, while alpha tricalcium phosphate (α-TCP, 98wt%) and HA (2wt%) were applied as the powder phase, 2.5wt% NaH2PO4 solution was used as liquid phase of cement. Before nano-CPC preparation, Si-stabilized α-TCP nanopowder with particle size of 10±3...
December 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28887959/%C3%AE-tcp-cements-prepared-by-syringe-foaming-influence-of-na2hpo4-and-surfactant-concentration
#8
A F Vásquez, S Domínguez, L A Loureiro Dos Santos
The lack of intrinsic open porosity in calcium phosphate cements slows down the resorption rate and bone ingrowth when implanted In Vivo. In this study, macroporous structures were obtained by mixing α-TCP cement with a foamed liquid phase containing different concentrations of sodium hydrogen phosphate and a nonionic surfactant. The cement paste was prepared by hand mixing in a novel system of two syringes connected by a tube. Two different liquid to powder (L/P) ratios were used to prepare the cement paste...
December 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28887211/gold-nanoparticles-in-injectable-calcium-phosphate-cement-enhance-osteogenic-differentiation-of-human-dental-pulp-stem-cells
#9
Yang Xia, Huimin Chen, Feimin Zhang, Chongyun Bao, Michael D Weir, Mark A Reynolds, Junqing Ma, Ning Gu, Hockin H K Xu
In this study, a novel calcium phosphate cement containing gold nanoparticles (GNP-CPC) was developed. Its osteogenic induction ability on human dental pulp stem cells (hDPSCs) was investigated for the first time. The incorporation of GNPs improved hDPSCs behavior on CPC, including better cell adhesion (about 2-fold increase in cell spreading) and proliferation, and enhanced osteogenic differentiation (about 2-3-fold increase at 14days). GNPs endow CPC with micro-nano-structure, thus improving surface properties for cell adhesion and subsequent behaviors...
September 5, 2017: Nanomedicine: Nanotechnology, Biology, and Medicine
https://www.readbyqxmd.com/read/28886100/biomechanical-evaluation-of-tibial-bone-adaptation-after-revision-total-knee-arthroplasty-a-comparison-of-different-implant-systems
#10
María Paz Quilez, Belen Seral, María Angeles Pérez
The best methods to manage tibial bone defects following total knee arthroplasty remain under debate. Different fixation systems exist to help surgeons reconstruct knee osseous bone loss (such as tantalum cones, cement, modular metal augments, autografts, allografts and porous metaphyseal sleeves) However, the effects of the various solutions on the long-term outcome remain unknown. In the present work, a bone remodeling mathematical model was used to predict bone remodeling after total knee arthroplasty (TKA) revision...
2017: PloS One
https://www.readbyqxmd.com/read/28881528/-clinical-research-of-minimally-invasive-spine-surgery-with-vesselplasty
#11
H Tang, P Jia, H Chen, L Bao, F Feng, J J Li
Objective: To evaluate the efficacy and safety of Vesselplasty in the treatment of osteoporotic vertebral fractures and vertebral metastases. Methods: From June 2010 to December 2016, data of 81 patients with spinal diseases treated with Vesselplasty in Department of Spinal Surgery, Beijing Friendship hospital, Capital Medical University were retrospectively analyzed. There are 49 cases of vertebral fractures with age (70.2±8.2) years. Among them, 16 cases have posterior vertebral wall breakage, but no symptoms of nerve injury...
September 5, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28876459/antibiotic-elution-from-acrylic-bone-cement-loaded-with-high-doses-of-tobramycin-and-vancomycin
#12
Joshua Slane, Bradley Gietman, Matthew Squire
Two-stage revision treatment of prosthetic joint infection (PJI) frequently employs the use of a temporary bone cement spacer loaded with multiple antibiotic types. Tobramycin and vancomycin are commonly used antibiotics in cement spacers, however, there is no consensus on the relative concentrations and combinations that should be used. Therefore, the purpose of this study was to investigate the influence of dual antibiotic loading on the total antibiotic elution and compressive mechanical properties of acrylic bone cement...
September 6, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28874983/posterior-vertebrectomy-and-circumferential-fusion-for-the-treatment-of-advanced-thoracolumbar-k%C3%A3-mmell-disease-with-neurologic-deficit
#13
Yongjae Cho
STUDY DESIGN: Single-center, retrospective case series. PURPOSE: To investigate the effectiveness of posterior vertebrectomy and circumferential fusion in patients with advanced Kümmell disease with neurologic deficit. OVERVIEW OF LITERATURE: Various surgical options exist for the treatment of Kümmell disease, and determination of the appropriate treatment is based on the clinical and radiologic status of the patient. However, surgical intervention is required for patients with advanced Kümmell disease accompanied by neurologic deficit...
August 2017: Asian Spine Journal
https://www.readbyqxmd.com/read/28873239/interventional-radiology-in-bone-metastases
#14
REVIEW
J Chiras, E Shotar, E Cormier, F Clarençon
Interventional radiology plays a significant role in the treatment of bone metastases by various techniques, percutaneous or endovascular. Vertebroplasty is the most well-studied technique for stabilisation of spine metastases as it induces satisfactory stabilisation of the vertebra and offers clear improvement of the quality of life. Due to the success of this technique cementoplasty of other bones, mainly pelvic girdle, has been largely developed. The development of reinforced cementoplasty allows treatment of pre-fractural osteolysis of some long bones...
September 5, 2017: European Journal of Cancer Care
https://www.readbyqxmd.com/read/28869829/strontium-doping-promotes-bioactivity-of-rhbmp-2-upon-calcium-phosphate-cement-via-elevated-recognition-and-expression-of-bmpr-ia
#15
Baolin Huang, Yu Tian, Wenjing Zhang, Yifan Ma, Yuan Yuan, Changsheng Liu
Preserving and improving osteogenic activity of bone morphogenetic protein-2 (BMP-2) upon implants remains one of the key limitations in bone regeneration. With calcium phosphate cement (CPC) as model, we have developed a series of strontium (Sr)-doped CPC (SCPC) to address this issue. The effects of fixed Sr on the bioactivity of recombinant human BMP-2 (rhBMP-2) as well as the underlying mechanism were investigated. The results suggested that the rhBMP-2-induced osteogenic activity was significantly promoted upon SCPCs, especially with a low amount of fixed Sr (SrCO3 content <10wt%)...
June 27, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28868202/a-thoracic-vertebral-localization-of-a-metastasized-cutaneous-merkel-cell-carcinoma-case-report-and-review-of-literature
#16
Rosario Maugeri, Antonella Giugno, Roberto G Giammalva, Carlo Gulì, Luigi Basile, Francesca Graziano, Domenico G Iacopino
BACKGROUND: Merkel cell carcinoma (MCC) is a rare neuroendocrine skin tumor, which may be related to sun exposure. It can metastasize to lungs, liver and bone, leading to severe morbidity and mortality. Vertebral metastases from MCC are rare. The authors report the tenth case in the literature, a 59-year-old patient with MCC, which was primarily localized in the scalp, and later provoked distant metastasis to the thoracic spinal column. CASE DESCRIPTION: A 59-year-old woman was admitted at our Unit of Neurosurgery with a 4-month history of progressive and severe dorsal back pain, without neurological signs...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28866230/strontium-doped-injectable-bone-cement-for-potential-drug-delivery-applications
#17
Ali Taha, Muhammad Akram, Zaidoon Jawad, Ammar Z Alshemary, Rafaqat Hussain
Microwave assisted wet precipitation method was used to synthesize calcium deficient strontium doped β-tricalcium phosphate (Sr-βTCP) with a chemical formula of Ca2.96-xSrx(PO4)2. Sr-βTCP was reacted with monocalcium phosphate monohydrate [Ca(H2PO4)2.H2O, MCPM] in presence of water to furnish corresponding Sr containing brushite cement (Sr-Brc). The samples were characterized by using X-ray diffractometry (XRD), Fourier transform infrared spectroscopy (FTIR) and field emission scanning electron microscopy (FESEM)...
November 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28866150/synthesis-and-study-of-thermal-mechanical-and-biodegradation-properties-of-chitosan-g-pmma-with-chicken-egg-shell-nano-cao-as-a-novel-bio-filler
#18
Arun K Pradhan, Prafulla K Sahoo
The important objective of this study is to evaluate the effect of chicken eggshell (nano-Cao) as a functionalized bio-filler on the mechanical strength and thermal stability of acrylic based bionanocomposite of chitosan grafted with poly(methyl methacrylate)(PMMA). The chitosan grafted PMMA adsorbed with functionalized biofiller was prepared via emulsion polymerisation technique and physicochemically characterized as bone graft substitute. The so prepared grafted bioactive bone cement (BBC) bionanocomposite (BNC), chitosan-g-PMMA/nano-CaO was characterized by FTIR, XRD, FESEM and TGA...
November 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28865450/elution-kinetics-of-vancomycin-and-gentamicin-from-carriers-and-their-effects-on-mesenchymal-stem-cell-proliferation-an-in-vitro-study
#19
Tomas Kucera, Lenka Ryskova, Tomas Soukup, Jana Malakova, Eva Cermakova, Pavel Mericka, Jakub Suchanek, Pavel Sponer
BACKGROUND: Musculoskeletal infections remain a major complication in orthopedic surgery. The local delivery of antibiotics provides the high levels required to treat an infection without systemic toxicity. However, the local toxicity of antibiotic carriers to the mesenchymal stem cells, as a result of both the peak concentrations and the type of carrier, may be significant. METHODS: To address this concern, the elution kinetics of vancomycin and gentamicin from several commercially available antibiotic carriers and several carriers impregnated by a surgeon (10 ml of each sterile carrier were manually mixed with a 500 mg vancomycin and an 80 mg gentamicin solution, and the duration of impregnation was 30 min) were assessed...
September 2, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28865420/risk-factors-for-failure-of-revision-total-hip-arthroplasty-using-a-kerboull-type-acetabular-reinforcement-device
#20
Shinya Hayashi, Takayuki Nishiyama, Shingo Hashimoto, Tomoyuki Matsumoto, Koji Takayama, Kazunari Ishida, Kotaro Nishida, Ryosuke Kuroda
BACKGROUND: The present study aimed to identify the risk factors associated with revision total hip arthroplasty (THA) failure using a Kerboull-type (KT) plate. METHODS: We analyzed 77 revision THAs using cemented acetabular components with a KT plate for aseptic loosening between May 2000 and March 2012. We examined the association of bone graft type, acetabular bone defects, age at the time of surgery, preoperative Japanese Orthopaedic Association (JOA) score, postoperative JOA hip score, and body mass index, with radiographic failure as the outcome...
September 2, 2017: BMC Musculoskeletal Disorders
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