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Mukta Wyawahare, Revathy Neelamegam, Saranya Vilvanathan, R Soundravally, A K Das, C Adithan
BACKGROUND: Genetic polymorphisms of the angiotensin-renin pathway have been thought to influence the development of diabetic nephropathy. However, there are conflicting results regarding this association in previous studies on populations with varying ethnicity. AIMS: Primary aim was to compare the frequency of distribution of angiotensin-converting enzyme (ACE) gene (insertion/deletion [I/D]) polymorphism in Tamilian Indian type 2 diabetic individuals with and without microalbuminuria...
2017: Clinical Medicine Insights. Endocrinology and Diabetes
Sabapathy Periyasamy, Mohan Sathya, Chennakesavan Karthick, Mahesh Kandasamy, Sellathamby Shanmugaapriya, Jeyavelu Tamilselvan, Kesavan Swaminathan Jayachandran, Muthuswamy Anusuyadevi
 Epidemiological studies state that dementia has multiple etiologies including genetic mutation, genetic variation, and environmental factors. Accumulating evidence suggests that dysregulation of cholesterol homeostasis is the major etiological factor in initiating neurodegeneration. Apolipoprotein E (APOE) polymorphic alleles and associated polymorphism of lipoprotein lipase (LPL) and cholesteryl ester transfer protein (CETP) that are important components in regulating cholesterol metabolism are implicated in neurodegenerative diseases...
2017: Journal of Alzheimer's Disease: JAD
Venugopal V, Amit Rathi, Nagarthna Raghuram
AIM: To study the effect of short term Yoga-based lifestyle intervention in the management of diabetes and pre-diabetes, through a 'pilot' community-based study. METHODS: A total of 1292 subjects with diagnosed type 2 diabetes and pre-diabetes were recruited from different States of India viz., Karnataka, Maharashtra, Gujarat, Rajasthan, and Tamilnadu participated in the study. Yoga-based lifestyle intervention was introduced through 10-day non-residential camps...
April 12, 2017: Diabetes & Metabolic Syndrome
N Kannan, S Balaji, N V Anil Kumar
BACKGROUND: The traditional Indian medicine 'Siddha' uses metals, metalloids and minerals including toxic ones with no proven toxicity. Thalagak karuppu (TK) is remarkably stable over a century and used for treating Suram (Fever), Kaasam (Cough), Elai (Tuberculosis) and Eraippu Erumal (Bronchial Asthma). OBJECTIVE: The present study addresses elemental and morphological characterization of therapeutic Siddha formulation: Thalagak karuppu (TK). MATERIALS AND METHODS: TK was purchased from the Indian Medical Practitioners Co-operative Pharmacy and Stores (IMCOPS) Ltd, Chennai, Tamilnadu, India...
July 2017: Journal of Ayurveda and Integrative Medicine
Anamika Gupta, Kuldip Gupta, Geeta Devi Leishangthem, Mandeep Singh Bal, N K Sood, Amarjit Singh
The present communication is a part of study conducted on 32 cases of bovine lymphadenopathies. Out of which, six cases of bovine theileriosis were diagnosed on the basis of peripheral blood smear examination and gross lesions in lymph nodes and visceral organs. Nested PCR using two primer sets N516/N517 and 14136/294 was conducted on samples collected from affected lymph nodes confirms Theileria annulata infection in five out of six cases. Sequencing analysis of amplified product showed 92, 94 and 93 % homology of isolate TH1_Bovine, TH2_Bovine and THEN_Bovine for T...
March 2017: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
Sundaram Selvam, Narayanasamy Murugesan, Chamukuttan Snehalatha, Arun Nanditha, Arun Raghavan, Mary Simon, Priscilla Susairaj, Ambady Ramachandran
AIMS: The aims were to assess effect of a short training programme on non-communicable diseases (NCDs), particularly diabetes on school teachers and also on students who were in turn educated by them. Lifestyle changes made by both groups were assessed 6months later. METHODS: Graduate teachers (n=1017) from 2 districts in Tamilnadu, India were trained using audio visual aids in batches of 100, on healthy lifestyle practices, prevention and management of diabetes...
March 2017: Diabetes Research and Clinical Practice
Sasank Kalipatnapu, Sivaraman Kuppuswamy, Giriprasad Venugopal, Venkatesh Kaliaperumal, Balamurugan Ramadass
BACKGROUND: Iron deficiency is associated with stunting and poor performance in children. Oral iron supplementation is widely promoted to correct iron deficiency. However, excess iron may be toxic to beneficial luminal gut bacteria and could support growth of pathobionts. OBJECTIVE: To analyze the fecal total iron concentration and fecal Lactobacillus levels in a cohort of stunted and normal children. DESIGN: The study was undertaken in two different locations...
January 11, 2017: Journal of Gastroenterology and Hepatology
A Chandrasekaran, A Naseerutheen, R Ravisankar
The dataset contains concentration of major and trace elements of ancient potteries from Tamilnadu and grouping different potteries from the statistical techniques of factor and cluster analysis (Figs. 2, 3 and 4). The major and trace elemental concentration data generated using energy dispersive X-ray fluorescence technique (EDXRF) and factor and cluster analysis data obtained using STATISTICA (10.0 version) software. The concentration of major and trace elements determines the type of clay minerals (Calcareous/Non-Calcareous and either low or high refractory) and firing atmosphere adopted by the artisans at the time of manufacture...
February 2017: Data in Brief
J Chandramohan, G Senthilkumar, M Suresh Gandhi, R Ravisankar
This article contains the chemical and geographical data and figures for the chemical data in sediments of East Coast (Pattipulam to Dhevanampattinam) of Tamilnadu. The obtained data are related to the research article "Heavy Metal Assessment in Sediment Samples Collected From Pattipulam to Dhevanampattinam along the East Coast of Tamil Nadu Using EDXRF Technique" (Chandramohan et al., 2016) [1]. Chemical data are collected from Energy dispersive X-ray fluorescence spectrometer (EDXRF). Furthermore, the obtained chemical data describes it in more detail in the figures...
December 2016: Data in Brief
S Manimaran, S Jayakumar, K Bhagya Lakshmi
Education Management Information System (EMIS) is a widely acceptable and developing technology within the Information Technology field. The advancement in technology in this century is being collaborated with scientific invention or explorer and information strengthening or development. This paper presents the results and experiences gained from applying students oriented EMIS for monitoring and managing mental health. The Mental Health of students depends on the acquiring adequate knowledge on basic concepts within a time period or academic schedule...
November 14, 2016: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
Karikalacholan Sivasankari, Santhanam Shanmughapriya, Kalimuthusamy Natarajaseenivasan
Humans are known to excrete leptospires in their urine after recovery from illness and there are reports showing development of asymptomatic leptospiruria in settings of high disease transmission. In this regard, we sought to evaluate the asymptomatic renal carriage status of humans in the highly endemic region of Tiruchirapalli district, Tamilnadu, India. A total of 245 asymptomatic participants were included. Urine and blood samples were collected and the extent of leptospiral infection was characterized by MAT, qPCR, 16S rRNA, and dot blot assay...
June 2016: Pathogens and Global Health
Narayanan Biju, Ganesan Sathiyaraj, Mithun Raj, Venu Shanmugam, Babu Baskaran, Umamaheswari Govindan, Gayathri Kumaresan, Karthick Kannan Kasthuriraju, Thampi Sam Raj Yohannan Chellamma
Hepatopancreatic microsporidiosis in cultivated Litopenaeus vannamei and Penaeus monodon is caused by the newly emerged pathogen Enterocytozoon hepatopenaei (EHP). It has been detected in shrimp cultured in China, Vietnam and Thailand and is suspected to have occurred in Malaysia and Indonesia and to be associated with severely retarded growth. Due to retarded shrimp growth being reported at farms in the major grow-out states of Tamilnadu, Andhra Pradesh and Odisha in India, shrimp were sampled from a total of 235 affected ponds between March 2014 and April 2015 to identify the presence of EHP...
August 9, 2016: Diseases of Aquatic Organisms
R Udhayakumar, P Manivannan, K Raghu, S Vaideki
Water is an important component to human life. The major aims of the present work are to assess the quality of the ground water and its impact in Villupuram District of Tamilnadu. The present study focus to bring an awareness among the people about the quality of ground water by taking water samples from various locations for Physico - Chemical analysis of the ground water. This analysis result was compared with the WHO, ICMR, USPH and European standards of drinking water quality parameters with the following water quality parameters namely pH, Electrical conductivity, Cl, , Na, K, Ca , Mg, Total dissolved solids, Total hardness, Dissolved oxygen, Fluoride etc...
December 2016: Ecotoxicology and Environmental Safety
Y Raghu, R Ravisankar, A Chandrasekaran, P Vijayagopal, B Venkatraman
The activity concentration of Ra, Th and K in brick samples used in Tiruvannamalai District of Tamilnadu has been determined using gamma ray spectrometry. The activity concentration ranges from BDL to 16.02 Bq kg, 17.86 to 120.19 Bq kg, 240.09 to 481.35 Bq kg for Ra, Th, and K, respectively. The concentration of these radionuclides is compared with reported data from other countries. The radium equivalent activity (Raeq), absorbed gamma dose rate (DR), annual effective dose rate (HR), annual gonadal dose equivalent (AGDE), criteria formula (CF), representative level index (RLI), activity utilization index (AUI), gamma index (Iγ), alpha index (Iα), the external hazard (Hex), and internal hazard (Hin) indices are calculated for the measured samples to assess the radiation hazards due to the use of these materials in the construction of dwellings...
September 2016: Health Physics
G Thiruvenkadam, Sharath Asokan, J Baby John, P R Geetha Priya
OBJECTIVE: The aim of the study was to assess the association of optimism and psychosocial well being of school going children on their oral health status. STUDY DESIGN: The study included 12- to 15-year-old school going children (N = 2014) from Tamilnadu, India. Optimism was measured using the revised version of the Life Orientation Test (LOT-R). A questionnaire was sent to the parents regarding their child's psychosocial behavior which included shyness, feeling inferiority, unhappiness and friendliness...
2016: Journal of Clinical Pediatric Dentistry
K Mohankumar, V Hariharan, N Prasada Rao
INTRODUCTION: Water is the vital resource, necessary for all aspects of human and ecosystem survival and health. Depending on the quality, bore water may be used for human consumption, irrigation purposes and livestock watering. The quality of bore water can vary widely depending on the quality of ground water that is its source. Pollutants are being added to the ground water system through human and natural processes. Solid waste from industrial units is being dumped near the factories, which react with percolating rainwater and reaches the ground water...
April 2016: Journal of Clinical and Diagnostic Research: JCDR
P Senthamarai Selvan, A Jebanesan, D Reetha
The distribution and abundance of various mosquito vectors is important in the determination of disease prevalence in disease endemic areas. The aim of the present study was to conduct regular entomological surveillance and to determine the relative abundance of tree hole mosquito species in Tamilnadu, India. In addition to this, the impact of weather-conditions on tree hole mosquito population were evaluated between June, 2014 and May, 2015. Six hills ranges viz., Anaimalai hills, Kodaikanal hills, Sitheri hills, Kolli hills, Yercaud hills, and Megamalai were selected, the immatures collected from tree holes by the help of suction tube...
July 2016: Acta Tropica
Murugesan Kanagavel, Alphonse Asirvatham Princy Margreat, Manivel Arunkumar, Shanmugarajan Gnanasekaran Prabhakaran, Santhanam Shanmughapriya, Kalimuthusamy Natarajaseenivasan
Here the rodent carrier status for the transmission of human leptospirosis in Tiruchirappalli, district, Tamil Nadu, India was assessed. The predominantly circulating leptospiral STs were recognized by multilocus sequence typing (MLST). A total of 113 rodents were trapped from different provinces of the Tiruchirappalli district. The most prevalent rodent was Bandicota bengalensis (37.2%), and of the total, 52.2% (n=59) rodents were found to be positive for leptospiral 16S rRNA. These results were validated with a leptospiral culture positivity of 45...
January 2016: Infection, Genetics and Evolution
Sujatha Somasundaram, Karunya Ravi, K Rajapandian, Deepa Gurunathan
CONTEXT: The optimum level of fluoride in drinking water is 0.7 to 1.2 ppm. Decreased fluoride concentration leads to increased risk of caries and increased concentration can lead to dental or skeletal fluorosis. One crore liters of water is supplied to Chennai and surrounding areas through pouches and bottles which carters about one third of city population. AIM: The aim of this study is to determine the fluoride concentration in top 10 bottled waters in Chennai and to check the accuracy of their labelling...
October 2015: Journal of Clinical and Diagnostic Research: JCDR
Sadish Kumar Thangavelu, Nehru Kasthuri, Vivekanandan Sundaram, Navneet Aravind, Nishant Bilakanti
BACKGROUND: In low-income countries with limited infrastructure, remote diagnoses are a sustainable solution to healthcare issues. Current electroencephalography (EEG) monitoring devices are very expensive and may not be feasible in rural areas. Because a seizure is nonstationary, composed of multiple frequencies, and difficult to acquire, visual and conventional frequency-based methods have limited application. MATERIALS AND METHODS: One hundred healthy individuals at their best possible conscious state and 25 patients with an epileptic seizure a few hours prior to the time of recording were chosen...
April 2016: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
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