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https://www.readbyqxmd.com/read/29042362/comparative-safety-of-direct-oral-anticoagulants-and-warfarin-in-venous-thromboembolism-multicentre-population-based-observational-study
#1
Min Jun, Lisa M Lix, Madeleine Durand, Matt Dahl, J Michael Paterson, Colin R Dormuth, Pierre Ernst, Shenzhen Yao, Christel Renoux, Hala Tamim, Cynthia Wu, Salaheddin M Mahmud, Brenda R Hemmelgarn
Objective To determine the safety of direct oral anticoagulant (DOAC) use compared with warfarin use for the treatment of venous thromboembolism.Design Retrospective matched cohort study conducted between 1 January 2009 and 31 March 2016.Setting Community based, using healthcare data from six jurisdictions in Canada and the United States.Participants 59 525 adults (12 489 DOAC users; 47 036 warfarin users) with a new diagnosis of venous thromboembolism and a prescription for a DOAC or warfarin within 30 days of diagnosis...
October 17, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29038717/acceptability-of-picture-archiving-and-communication-system-pacs-among-hospital-healthcare-personnel-based-on-a-unified-theory-of-acceptance-and-use-of-technology
#2
Maryam Ahmadi, Nahid Mehrabi, Abbas Sheikhtaheri, Mojtaba Sadeghi
BACKGROUND AND AIM: The picture archiving and communication system (PACS) is a healthcare system technology which manages medical images and integrates equipment through a network. There are some theories about the use and acceptance of technology by people to describe the behavior and attitudes of end users towards information technologies. We investigated the influential factors on users' acceptance of PACS in the military hospitals of Tehran. METHODS: In this applied analytical and cross-sectional study, 151 healthcare employees of military hospitals who had experience in using the PACS system were investigated...
September 2017: Electronic Physician
https://www.readbyqxmd.com/read/29031014/indirect-method-for-validating-transference-of-reference-intervals
#3
Simon Lykkeboe, Claus Gyrup Nielsen, Peter Astrup Christensen
BACKGROUND: Transference of reference intervals (RIs) from multicentre studies are often verified by use of a small number of samples from reference individuals or by the use of one serum sample (Serum X for NORIP RI). Despite recommended and appropriate methods, both have inconveniencies and drawbacks. Several attempts have been made to develop an indirect method, which uses historical data from the laboratory. These methods are retrospective relying on older test results. A near prospective method would be preferable for the laboratories introducing new methods or changing analytical platforms...
October 14, 2017: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/29026338/utilization-of-healthcare-services-in-postpartum-women-in-the-philippines-who-delivered-at-home-and-the-effects-on-their-health-a-cross-sectional-analytical-study
#4
Tadashi Yamashita, Maria Teresa Reyes Tuliao, Magdalena Concel Meana, Sherri Ann Suplido, Cecilia L Llave, Yuko Tanaka, Hiroya Matsuo
BACKGROUND: A low ratio of utilization of healthcare services in postpartum women may contribute to maternal deaths during the postpartum period. The maternal mortality ratio is high in the Philippines. The aim of this study was to examine the current utilization of healthcare services and the effects on the health of women in the Philippines who delivered at home. METHODS: This was a cross-sectional analytical study, based on a self-administrated questionnaire, conducted from March 2015 to February 2016 in Muntinlupa, Philippines...
2017: International Journal of Women's Health
https://www.readbyqxmd.com/read/29017702/collaborative-study-on-saccharide-quantification-of-the-haemophilus-influenzae-type-b-component-in-liquid-vaccine-presentations
#5
U Rosskopf, A Daas, E Terao, C von Hunolstein
Before release onto the market, it must be demonstrated that the total and free polysaccharide (poly ribosyl-ribitol-phosphate, PRP) content of Haemophilus influenzae type b (Hib) vaccine complies with requirements. However, manufacturers use different methods to assay PRP content: a national control laboratory must establish and validate the relevant manufacturer methodology before using it to determine PRP content. An international study was organised by the World Health Organization (WHO), in collaboration with the Biological Standardisation Programme (BSP) of the Council of Europe/European Directorate for the Quality of Medicines & HealthCare (EDQM) and of the European Union Commission, to verify the suitability of a single method for determining PRP content in liquid pentavalent vaccines (DTwP-HepB-Hib) containing a whole-cell pertussis component...
2017: Pharmeuropa Bio & Scientific Notes
https://www.readbyqxmd.com/read/29017488/understanding-collaborative-care-implementation-in-the-department-of-veterans-affairs-core-functions-and-implementation-challenges
#6
Jessica M Lipschitz, Justin K Benzer, Christopher Miller, Siena R Easley, Jenniffer Leyson, Edward P Post, James F Burgess
BACKGROUND: The collaborative care model is an evidence-based practice for treatment of depression in which designated care managers provide clinical services, often by telephone. However, the collaborative care model is infrequently adopted in the Department of Veterans Affairs (VA). Almost all VA medical centers have adopted a co-located or embedded approach to integrating mental health care for primary care patients. Some VA medical centers have also adopted a telephone-based collaborative care model where depression care managers support patient education, patient activation, and monitoring of adherence and progress over time...
October 10, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29017389/the-canadian-laboratory-initiative-on-pediatric-reference-intervals-a-caliper-white-paper
#7
Khosrow Adeli, Victoria Higgins, Karin Trajcevski, Nicole White-Al Habeeb
Laboratory investigations provide physicians with objective data to aid in disease diagnosis, clinical decision making, and patient follow up. Clinical interpretation of laboratory test results relies heavily on the availability of appropriate population-based reference intervals (i.e. normative values) or decision limits developed through clinical outcome studies. Although reference intervals are fundamental to accurate laboratory test interpretation, and thus critically important to healthcare, the need for sound evidence-based reference intervals has been largely overlooked, particularly in the pediatric population...
October 11, 2017: Critical Reviews in Clinical Laboratory Sciences
https://www.readbyqxmd.com/read/28993317/proportionate-methods-for-evaluating-a-simple-digital-mental-health-tool
#8
E Bethan Davies, Michael P Craven, Jennifer L Martin, Lucy Simons
BACKGROUND: Traditional evaluation methods are not keeping pace with rapid developments in mobile health. More flexible methodologies are needed to evaluate mHealth technologies, particularly simple, self-help tools. One approach is to combine a variety of methods and data to build a comprehensive picture of how a technology is used and its impact on users. OBJECTIVE: This paper aims to demonstrate how analytical data and user feedback can be triangulated to provide a proportionate and practical approach to the evaluation of a mental well-being smartphone app (In Hand)...
October 9, 2017: Evidence-based Mental Health
https://www.readbyqxmd.com/read/28991600/the-effects-of-reflective-training-on-the-disposition-of-critical-thinking-for-nursing-students-in-china-a-controlled-trial
#9
Caihong Zhang, Huiying Fan, Jieqiong Xia, Honghua Guo, Xinjun Jiang, Yane Yan
PURPOSE: The aim of this study was to evaluate the effects of reflective trainings for nursing students on their critical thinking disposition. METHODS: A total of 157 senior undergraduate nursing students sampled from Hainan Medical University in China participated in this study in 2014. They were randomly divided into experimental and control groups. The experimental group students were provided the reflective training during their entire 12-month clinical internship, whereas students in the control group were requested to keep their reflective diaries but without a formal training...
September 2017: Asian Nursing Research
https://www.readbyqxmd.com/read/28989219/task-driven-orbit-design-and-implementation-on-a-robotic-c-arm-system-for-cone-beam-ct
#10
S Ouadah, M Jacobson, J W Stayman, T Ehtiati, C Weiss, J H Siewerdsen
PURPOSE: This work applies task-driven optimization to the design of non-circular orbits that maximize imaging performance for a particular imaging task. First implementation of task-driven imaging on a clinical robotic C-arm system is demonstrated, and a framework for orbit calculation is described and evaluated. METHODS: We implemented a task-driven imaging framework to optimize orbit parameters that maximize detectability index d'. This framework utilizes a specified Fourier domain task function and an analytical model for system spatial resolution and noise...
March 2017: Proceedings of SPIE
https://www.readbyqxmd.com/read/28984353/care-maps-for-children-with-medical-complexity
#11
Sherri Adams, David Nicholas, Sanjay Mahant, Natalie Weiser, Ronik Kanani, Katherine Boydell, Eyal Cohen
AIM: Children with medical complexity require multiple providers and services to keep them well and at home. A care map is a patient/family-created diagram that pictorially maps out this complex web of services. This study explored what care maps mean for families and healthcare providers to inform potential for clinical use. METHOD: Parents (n=15) created care maps (hand drawn n=10 and computer-generated n=5) and participated in semi-structured interviews about the process of developing care maps and their perceived impact...
October 6, 2017: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/28979756/the-knowledge-of-hand-hygiene-among-the-healthcare-workers-of-two-teaching-hospitals-in-mashhad
#12
Hosein Zakeri, Fatemeh Ahmadi, Ehsan Rafeemanesh, Lahya Afshari Saleh
INTRODUCTION: Healthcare-associated infections (HAIs) affect millions of patients worldwide annually. Hand hygiene (HH) has been identified as the single most important factor preventing HAIs. The aim of this study was to determine the knowledge regarding hand hygiene practices amongst health care workers, and identifying the areas of gaps in their knowledge. METHODS: This cross-sectional analytic study was conducted in two university hospitals in Mashhad, Iran between May 2014 and September 2015...
August 2017: Electronic Physician
https://www.readbyqxmd.com/read/28977280/-the-regionalized-healthcare-network-in-santa-catarina-state-brazil-from-2011-to-2015-governance-system-and-oral-healthcare
#13
Heloisa Godoi, Selma Regina de Andrade, Ana Lúcia Schaefer Ferreira de Mello
: The objective was to describe the governance system used in structuring the regionalized healthcare network in Santa Catarina State, Brazil, based on the Bipartite Inter-Managerial Commission (CIB), with a focus on structuring of oral healthcare. This was a qualitative, exploratory-descriptive documental study, based on the foundations of governance as an analytical tool through identification of the dimensions actors, norms, nodal points, and processes. Secondary data were collected from the minutes of CIB meetings held from January 2011 to December 2015...
September 28, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/28977271/-health-workers-experiences-in-dealing-with-the-neoliberal-logic-a-study-of-primary-care-in-colombia-and-brazil
#14
Johanna Garrido-Pinzón, Marcia Hespanhol Bernardo
: The aim of this study was to analyze the experiences of primary healthcare workers in the public health systems in Colombia and Brazil in relation to the neoliberal logic. These two cases are relevant to public health research, as examples of health systems that emerged from opposing guidelines: the Colombian system was created at the government level with a marked private-sector influence, while the Brazilian system was an important conquest by social movements. Based on the Social Psychology of Work, this was a qualitative and empirical study...
September 28, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/28975531/the-effectiveness-of-strength-based-solution-focused-brief-therapy-in-medical-settings-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#15
REVIEW
Anao Zhang, Cynthia Franklin, Jennifer Currin-McCulloch, Sunyoung Park, Johnny Kim
This meta-analysis synthesized randomized controlled trials of solution focused brief therapy (SFBT) in medical settings for patients' health-related psychosocial (e.g., depression, psychosocial adjustment to illness), behavioral (e.g., physical activity, nutrition score), and functional health (e.g., BMI, individual strength) outcomes. Medical setting is defined in this study as any healthcare setting that primarily focuses on patients' physical wellbeing. A comprehensive search strategy across five electronic databases, four academic journals, three professional websites, and reference lists of included articles resulted in a final sample of nine studies for meta-analytic synthesis...
October 3, 2017: Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/28975010/budget-impact-of-a-comprehensive-nutrition-focused-quality-improvement-program-for-malnourished-hospitalized-patients
#16
Suela Sulo, Josh Feldstein, Jamie Partridge, Bjoern Schwander, Krishnan Sriram, Wm Thomas Summerfelt
BACKGROUND: Nutrition interventions can alleviate the burden of malnutrition by improving patient outcomes; however, evidence on the economic impact of medical nutrition intervention remains limited. A previously published nutrition-focused quality improvement program targeting malnourished hospitalized patients showed that screening patients with a validated screening tool at admission, rapidly administering oral nutritional supplements, and educating patients on supplement adherence result in significant reductions in 30-day unplanned readmissions and hospital length of stay...
July 2017: American Health & Drug Benefits
https://www.readbyqxmd.com/read/28972860/evaluating-the-economic-impact-of-palliative-and-end-of-life-care-interventions-on-intensive-care-unit-utilization-and-costs-from-the-hospital-and-healthcare-system-perspective
#17
Nita Khandelwal, Lyndia C Brumback, Scott D Halpern, Norma B Coe, Babette Brumback, J Randall Curtis
Purpose of report: Understanding the impact of palliative care interventions on intensive care unit (ICU) costs and utilization is critical for demonstrating the value of palliative care. Performing these economic assessments, however, can be challenging. The purpose of this special report is to highlight and discuss important considerations when assessing ICU utilization and costs from the hospital perspective, with the goal of providing recommendations on methods to consider for future analyses. FINDINGS: ICU length of stay (LOS) and associated costs of care are common and important outcome measures, but must be analyzed properly to yield valid conclusions...
October 3, 2017: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/28966101/rapid-discrimination-and-quantification-analysis-of-five-antineoplastic-drugs-in-aqueous-solutions-using-raman-spectroscopy
#18
Laetitia Minh Mai Lê, Marion Berge, Ali Tfayli, Jiangyan Zhou, Patrice Prognon, Arlette Baillet-Guffroy, Eric Caudron
The aim of this study was to assess the ability of Raman spectroscopy to discriminate and quantify five antineoplastic drugs in an aqueous matrix at low concentrations before patient administration. Five antineoplastic drugs were studied at therapeutic concentrations in aqueous 0.9% sodium chloride: 5-fluorouracil (5FU), gemcitabine (GEM), cyclophophamide (CYCLO), ifosfamide (IFOS) and doxorubicin (DOXO). All samples were packaged in glass vials and analyzed using Raman spectrometry from 400 to 4000cm(-1). Discriminant analyses were performed using Partial Least Squares Discriminant Analysis (PLS-DA) and quantitative analyses using PLS regression...
September 29, 2017: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28964431/reporting-to-improve-reproducibility-and-facilitate-validity-assessment-for-healthcare-database-studies-v1-0
#19
Shirley V Wang, Sebastian Schneeweiss, Marc L Berger, Jeffrey Brown, Frank de Vries, Ian Douglas, Joshua J Gagne, Rosa Gini, Olaf Klungel, C Daniel Mullins, Michael D Nguyen, Jeremy A Rassen, Liam Smeeth, Miriam Sturkenboom
PURPOSE: Defining a study population and creating an analytic dataset from longitudinal healthcare databases involves many decisions. Our objective was to catalogue scientific decisions underpinning study execution that should be reported to facilitate replication and enable assessment of validity of studies conducted in large healthcare databases. METHODS: We reviewed key investigator decisions required to operate a sample of macros and software tools designed to create and analyze analytic cohorts from longitudinal streams of healthcare data...
September 2017: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/28957422/the-use-of-antenatal-care-in-two-rural-districts-of-upper-west-region-ghana
#20
Joshua Sumankuuro, Judith Crockett, Shaoyu Wang
BACKGROUND: Despite decades of implementation of maternity healthcare programmes, including a focus on increasing the use of antenatal care (ANC) and concomitant birth preparedness and complication readiness (BPCR), the uptake of ANC continues to be below expectations in many developing countries. This has attendant implications for maternal and infant morbidity and mortality rates. Known barriers to ANC use include cost, distance to health care services and forces of various socio-cultural beliefs and practices...
2017: PloS One
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