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https://www.readbyqxmd.com/read/29754463/intestinal-failure-the-evolving-demographic-and-patient-outcomes-on-home-parenteral-nutrition
#1
Sarah Kate Brown, Natalie Davies, Enda Smyth, Nicky Heather, Caroline Cole, Simon Charles Keys, Robert Mark Beattie, Akshay Batra
AIM: We performed this study to examine and understand the evolving demographics and changing outcomes of intestinal failure, and its implications for healthcare delivery. METHOD: We conducted a retrospective analysis of outcome data of children on home Parenteral Nutrition (HPN), over a 15 year period. RESULTS: 31 patients received HPN, 15 for short bowel syndrome (SBS), 8 neuromuscular disease (NMD) and 8 for other causes. The HPN prevalence increased from 1...
May 13, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29722835/catheter-related-bloodstream-infections-in-patients-with-intestinal-failure-receiving-home-parenteral-support-risks-related-to-a-catheter-salvage-strategy
#2
Siri Tribler, Christopher F Brandt, Kristian A Fuglsang, Michael Staun, Per Broebech, Claus E Moser, Thomas Scheike, Palle B Jeppesen
Background: In intestinal failure (IF) patients receiving home parenteral support (HPS), catheter-related bloodstream infections (CRBSIs) frequently result in replacement of their tunneled central venous catheters (CVCs), which may lead to future loss of central venous access. Objective: This observational study investigated the consequences of a catheter-salvage strategy related to CRBSIs. Design: All CRBSIs from 2002 to 2016 in the Copenhagen IF and microbiological databases were retrospectively analyzed...
May 1, 2018: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29720244/administration-of-taurolidine-citrate-lock-solution-for-prevention-of-central-venous-catheter-infection-in-adult-neutropenic-haematological-patients-a-randomised-double-blinded-placebo-controlled-trial-taurcat
#3
C Gudiol, S Nicolae, C Royo-Cebrecos, M Aguilar-Guisado, I Montero, C Martín-Gandul, M Perayre, D Berbel, M Encuentra, M Arnan, J M Cisneros-Herreros, J Carratalà
BACKGROUND: Catheter-related bloodstream infection (CRBSI) is one of the most frequent complications in patients with cancer who have central venous catheters (CVCs) implanted and is associated with substantial morbidity and mortality. Taurolidine is a non-antibiotic agent with broad-spectrum antimicrobial activity, which has been used as a lock solution to prevent CRBSI in some settings. However, little is known about its usefulness in high-risk adult neutropenic patients with cancer...
May 2, 2018: Trials
https://www.readbyqxmd.com/read/29667048/ethanol-lock-is-effective-on-reducing-the-incidence-of-tunneled-catheter-related-bloodstream-infections-in-hemodialysis-patients-a-systematic-review-and-meta-analysis
#4
REVIEW
Tingting Zhao, Hong Liu, Jibin Han
PURPOSE: The purpose of this meta-analysis is to evaluate the effect of ethanol lock on the incidence of catheter-related bloodstream infection (CRBSI) in patients with central venous catheters. METHODS: RCTs comparing ethanol lock with another solution lock for prevention of CRBSI were obtained by searching databases of PubMed, Embase, Web of Science and Cochrane Central Register of clinical trials for eligible randomized controlled trials (inception to December 2017)...
April 17, 2018: International Urology and Nephrology
https://www.readbyqxmd.com/read/29661631/chlorhexidine-containing-dressings-in-the-prevention-of-central-venous-catheter-related-bloodstream-infections-a-cost-and-resource-utilization-analysis
#5
Sebastian M Heimann, Lena M Biehl, Jörg Janne Vehreschild, Bernd Franke, Oliver A Cornely, Maria J G T Vehreschild
BACKGROUND: A recent study reported a reduction in probable/definite central venous catheter (CVC)-related bloodstream infections (CRBSIs) in neutropenic high-risk patients using CVC dressings with a chlorhexidine-containing gel pad. METHODS: Based on published data, a health-economic analysis was performed to analyze the economic effect of using CVC dressings with a chlorhexidine-containing gel pad compared to non-chlorhexidine control dressings. A micro-costing approach was used to determine CRBSI-related direct treatment cost factors...
April 13, 2018: American Journal of Infection Control
https://www.readbyqxmd.com/read/29627326/one-percent-chlorhexidine-alcohol-for-preventing-central-venous-catheter-related-infection-during-intensive-chemotherapy-for-patients-with-haematologic-malignancies
#6
Shimon Ohtake, Hiromichi Takahashi, Masaru Nakagawa, Yoshihito Uchino, Katsuhiro Miura, Noriyoshi Iriyama, Tomohiro Nakayama, Yoshihiro Hatta, Masami Takei
A central venous catheter (CVC) is a catheter placed into a large vein, and is used for chemotherapy administration. However, there is little confirmatory data on which antiseptic-such as chlorhexidine or povidone-iodine (PI) -is more protective against CVC-related infectious complications in patients receiving intensive chemotherapy. We aimed to compare the effectiveness of 1% chlorhexidine gluconate in 70% alcohol (CH) vs. PI for skin disinfection before CVC insertion in patients receiving intensive chemotherapy...
April 4, 2018: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/29615168/reasons-for-removal-of-non-tunneled-double-lumen-catheters-in-incident-dialysis-patients
#7
Ruqaya Qureshi, Beena Salman, Salman Imtiaz, Murtaza F Drohlia, Aasim Ahmad
OBJECTIVE: To evaluate the reasons of removal of non-tunneled double lumen catheters (NTDLC) in incident hemodialysis (HD) patients in a tertiary renal care hospital. STUDY DESIGN: Observational retrospective study. PLACE AND DURATION OF STUDY: Department of Nephrology, The Kidney Centre Postgraduate Training Institute (TKC PGTI), Karachi, from June 2015 to May 2016. METHODOLOGY: All patients were selected who had naive NTDLC placement at TKC PGTI either in Emergency Room (ER) or Intensive Care Unit (ICU) during the study period...
April 2018: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/29563910/molecular-epidemiology-of-staphylococcus-epidermidis-implicated-in-catheter-related-bloodstream-infections-at-an-academic-hospital-in-pretoria-south-africa
#8
Marthie M Ehlers, Wilhelmina Strasheim, Michelle Lowe, Veronica Ueckermann, Marleen M Kock
Staphylococcus epidermidis is one of the most prevalent pathogens implicated in catheter-related bloodstream infections (CRBSI) at an academic hospital in Pretoria, South Africa. Little is known about the clonality and the prevalence of antibiotic resistance and virulence genes in S. epidermidis (e.g., ica AB, IS 256, mec A, and qac A/B). A total of 508 intravascular catheters (IVCs) from 331 patients were submitted for culture from May to October 2013. Only 50% ( n = 253/508) of the IVCs were accompanied by blood cultures (BCs) taken within 48 h...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29525366/comparison-of-complications-in-midlines-versus-central-venous-catheters-are-midlines-safer-than-central-venous-lines
#9
Ammara Mushtaq, Bhagyashri Navalkele, Maninder Kaur, Amar Krishna, Aleena Saleem, Natasha Rana, Sonia Gera, Suganya Chandramohan, Malini Surapaneni, Teena Chopra
BACKGROUND: With the rising use of midline catheters (MCs), validation of their safety is essential. Our study aimed to evaluate the incidence of bloodstream infections (BSIs) and other complications related to the use of MCs and central venous catheters (CVCs). METHODS: A retrospective cohort study was performed at a tertiary care hospital in Detroit, Michigan, from March-September 2016. Adult patients with either MC or CVC were included. Outcomes assessed were catheter-related BSI (CRBSI), mechanical complications, hospital length of stay, readmission within 90 days of discharge (RA), and mortality...
March 7, 2018: American Journal of Infection Control
https://www.readbyqxmd.com/read/29446842/epidemiology-and-risk-factors-for-outpatient-acquired-catheter-related-bloodstream-infections-in-children-receiving-home-parenteral-nutrition
#10
Laura J Wozniak, Hannah M Bechtold, Laurie E Reyen, Alvin P Chan, Elizabeth A Marcus, Jorge H Vargas
BACKGROUND: Few studies have examined the epidemiology and risk factors for the development of outpatient-acquired catheter-related bloodstream infections (CRBSIs) in children receiving home parenteral nutrition. This study aimed to (1) characterize the incidence, clinical presentation, and epidemiology of CRBSIs and (2) identify risk factors for CRBSIs in children receiving home parenteral nutrition. METHODS: A longitudinal database approved by our Institutional Review Board was created to prospectively track CRBSIs in the UCLA pediatric population from January to December 2012...
February 15, 2018: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29443394/catheter-related-bloodstream-infections-in-adults-receiving-home-parenteral-nutrition-substantial-differences-in-incidence-comparing-a-strict-microbiological-to-a-clinically-based-diagnosis
#11
Siri Tribler, Christopher F Brandt, Mark Hvistendahl, Michael Staun, Per Brøbech, Claus E Moser, Palle B Jeppesen
BACKGROUND: A common complication in patients receiving home parenteral nutrition (HPN) is catheter-related bloodstream infections (CRBSIs). The CRBSI incidence has been advocated as an outcome parameter assessing the quality of care. This study aimed to illustrate how the use of different CRBSI definitions affects the reported incidence. MATERIALS AND METHODS: In an observational study based on the Copenhagen intestinal failure database, all clinically reported CRBSIs from 2002-2013 were compared with data from the affiliated microbiological database according to recommended CRBSI criteria...
February 2018: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29432818/differential-time-to-positivity-of-central-and-peripheral-blood-cultures-is-inaccurate-for-the-diagnosis-of-staphylococcus-aureus-long-term-catheter-related-sepsis
#12
H Bouzidi, A Emirian, A Marty, E Chachaty, A Laplanche, B Gachot, F Blot
OBJECTIVES: Differential time to positivity of cultures of blood drawn simultaneously from central venous catheter and peripheral sites is widely used to diagnose catheter-related bloodstream infections without removing the catheter. However, the accuracy of this technique for some pathogens, such as Staphylococcus aureus, is debated in routine practice. METHODS: In a 320-bed reference cancer centre, the charts of patients with at least one blood culture positive for S...
February 10, 2018: Journal of Hospital Infection
https://www.readbyqxmd.com/read/29422728/multicenter-observational-study-to-evaluate-epidemiology-and-resistance-patterns-of-common-intensive-care-unit-infections
#13
Ramesh Venkataraman, Jigeeshu V Divatia, Nagarajan Ramakrishnan, Rajesh Chawla, Pravin Amin, Palepu Gopal, Dhruva Chaudhry, Kapil Zirpe, Babu Abraham
Background: There is limited data regarding the microbiology of Intensive Care Unit (ICU)-acquired infections, such as ventilator-associated pneumonia (VAP), catheter-associated urinary tract infections (CAUTI), and catheter-related bloodstream infections (CRBSI) from India. Objectives: To explore the microbiology and resistance patterns of ICU-acquired infections and evaluate their outcomes. Materials and Methods: This was a multicenter observational study, conducted by Indian Society of Critical Care Medicine (MOSER study) between August 2011 and October 2012...
January 2018: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/29412895/executive-summary-diagnosis-and-treatment-of-catheter-related-bloodstream-infection-clinical-guidelines-of-the-spanish-society-of-clinical-microbiology-and-infectious-diseases-seimc-and-the-spanish-society-of-intensive-care-medicine-and-coronary-units-semicyuc
#14
Fernando Chaves, José Garnacho-Montero, José Luis Del Pozo, Emilio Bouza, José Antonio Capdevila, Marina de Cueto, M Ángeles Domínguez, Jaime Esteban, Nuria Fernández-Hidalgo, Marta Fernández Sampedro, Jesús Fortún, María Guembe, Leonardo Lorente, Jose Ramón Paño, Paula Ramírez, Miguel Salavert, Miguel Sánchez, Jordi Vallés
Catheter-related bloodstream infections (CRBSI) constitute an important cause of hospital-acquired infection associated with morbidity, mortality, and cost. The aim of these guidelines is to provide updated recommendations for the diagnosis and management of CRBSI in adults. Prevention of CRBSI is excluded. Experts in the field were designated by the two participating Societies (Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica and the Sociedad Española de Medicina Intensiva, Crítica y Unidades Coronarias)...
February 2018: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/29406956/diagnosis-and-treatment-of-catheter-related-bloodstream-infection-clinical-guidelines-of-the-spanish-society-of-infectious-diseases-and-clinical-microbiology-and-seimc-and-the-spanish-society-of-spanish-society-of-intensive-and-critical-care-medicine-and-coronary
#15
F Chaves, J Garnacho-Montero, J L Del Pozo, E Bouza, J A Capdevila, M de Cueto, M Á Domínguez, J Esteban, N Fernández-Hidalgo, M Fernández Sampedro, J Fortún, M Guembe, L Lorente, J R Paño, P Ramírez, M Salavert, M Sánchez, J Vallés
Catheter-related bloodstream infections (CRBSI) constitute an important cause of hospital-acquired infection associated with morbidity, mortality, and cost. The aim of these guidelines is to provide updated recommendations for the diagnosis and management of CRBSI in adults. Prevention of CRBSI is excluded. Experts in the field were designated by the two participating Societies (the Spanish Society of Infectious Diseases and Clinical Microbiology and [SEIMC] and the Spanish Society of Spanish Society of Intensive and Critical Care Medicine and Coronary Units [SEMICYUC])...
January 2018: Medicina Intensiva
https://www.readbyqxmd.com/read/29399528/anti-fouling-strategies-for-central-venous-catheters
#16
REVIEW
Alex Wallace, Hassan Albadawi, Nikasha Patel, Ali Khademhosseini, Yu Shrike Zhang, Sailendra Naidu, Grace Knuttinen, Rahmi Oklu
Central venous catheters (CVCs) are ubiquitous in the healthcare industry and carry two common complications, catheter related infections and occlusion, particularly by thrombus. Catheter-related bloodstream infections (CRBSI) are an important cause of nosocomial infections that increase patient morbidity, mortality, and hospital cost. Innovative design strategies for intravenous catheters can help reduce these preventable infections. Antimicrobial coatings can play a major role in preventing disease. These coatings can be divided into two major categories: drug eluting and non-drug eluting...
December 2017: Cardiovascular Diagnosis and Therapy
https://www.readbyqxmd.com/read/29385236/strategies-to-reduce-catheter-related-bloodstream-infections-in-pediatric-patients-receiving-home-parenteral-nutrition-the-efficacy-of-taurolidine-citrate-prophylactic-locking
#17
Cecile Lambe, Catherine Poisson, Cecile Talbotec, Olivier Goulet
BACKGROUND: Catheter-related bloodstream infections (CRBSIs) remain a major issue in patients who are receiving home parenteral nutrition (HPN). The aim of this interventional study was to assess the impact of a new strategy using taurolidine-citrate (T-C) prophylactic locks on the CRBSI rate in children with intestinal failure who are receiving HPN. METHODS: The rate of CRBSIs was monitored every calendar year in a prospective cohort of 195 children with intestinal failure...
January 31, 2018: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29330994/pattern-of-causative-micro-organisms-in-catheter-related-blood-stream-infections-in-dialysis-patients-experience-from-saudi-arabia
#18
Bilal Mohsin
BACKGROUND: Catheter related blood stream infections (CRBSI) are the leading cause of morbidity in HD patients. The majority of these infections relate to haemodialysis catheters. There is a paucity of local data on microbial agents responsible for CRBSI in our region. This prompted our study. METHODS: This Prospective observatory survey was conducted in Department of Nephrology, King Fahd Hospital, Hofuf KSA from Nov 2014 to Jan 2017 (26 months). It was performed on dialysis patients with HD catheters who developed features of CRBSI...
October 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/29330016/clinical-impact-of-delayed-catheter-removal-for-patients-with-central-venous-catheter-related-gram-negative-bacteraemia
#19
Y-M Lee, C Moon, Y J Kim, H J Lee, M S Lee, K-H Park
BACKGROUND: Gram-negative bacteria are increasingly the cause of catheter-related bloodstream infection (CRBSI), and the prevalence of multi-drug-resistant strains is rising rapidly. This study evaluated the impact of delayed central venous catheter (CVC) removal on clinical outcomes in patients with Gram-negative CRBSI. METHODS: Between January 2007 and December 2016, patients with Gram-negative bacteraemia and CVC placement, from two tertiary care hospitals, were included retrospectively...
May 2018: Journal of Hospital Infection
https://www.readbyqxmd.com/read/29307014/stenotrophomonas-maltophilia-bacteremia-and-pneumonia-at-a-tertiary-care-oncology-center-a-review-of-16-years
#20
Consuelo Velázquez-Acosta, Sugehily Zarco-Márquez, Mari Carmen Jiménez-Andrade, Patricia Volkow-Fernández, Patricia Cornejo-Juárez
PURPOSE: The aim of this study was to describe the clinical characteristics and antimicrobial patterns of Stenotrophomonas maltophilia bloodstream infections (BSI) and pneumonia episodes in patients with cancer. METHODS: Patients with S. maltophilia BSI or pneumonia admitted from 1 Jan. 2000 to 31 Dec. 2016 were identified at the Instituto Nacional de Cancerología (INCan), a tertiary-care oncology hospital in Mexico City. RESULTS: During the study period, there were 171 isolates identified...
January 7, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
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