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https://www.readbyqxmd.com/read/28918617/right-ventricular-thrombosis-combined-with-fetal-death-and-acrocyanosis-in-pregnancy
#1
Feridoun Sabzi, Aghigh Heidari
Prepartum or postpartum right ventricular thrombosis (RVT) is an exceedingly rare and potentially lethal phenomenon in pregnancy. We here report a case of a pregnant patient with near term pregnancy admitted for dyspnea, amniotic fluids discharge and labor pain in a gynecology center that an eight-month dead fetus was diagnosed and delivered vaginally by induction. A post delivery period was complicated by aggravation of her dyspnea and pleuritic chest pain that she referred for further evaluation in our cardiac center...
July 2017: Acta Medica Iranica
https://www.readbyqxmd.com/read/28918594/the-association-of-knee-structural-pathology-with-pain-at-the-knee-is-modified-by-pain-at-other-sites-in-those-with-knee-osteoarthritis
#2
Feng Pan, Jing Tian, Dawn Aitken, Flavia Cicuttini, Tania Winzenberg, Graeme Jones
The objective of this study was to investigate the associations of knee structural abnormalities with different patterns of pain. A total of 891 participants (average age 63 years; range 50 to 80 years) participated in this study. Presence of pain at the neck, back, hands, shoulders, hips, knees, and feet was assessed by questionnaire. Participants were categorized as having no pain at any site (no pain), pain only at the knee (KP), pain at other sites but not the knee (OP), and pain at the knee and other sites (KOP)...
September 16, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28918579/analysis-of-undesirable-sequelae-of-sentinel-node-surgery-in-breast-cancer-patients-a-prospective-cohort-study
#3
Dominika Kozak, Iwona Głowacka-Mrotek, Tomasz Nowikiewicz, Zygmunt Siedlecki, Wojciech Hagner, Magdalena Sowa, Wojciech Zegarski
Use of sentinel lymph node biopsy limits the frequency and severity of sequelae of surgical treatment. However, the procedure itself may not be completely free of complications. The goal of this work was to analyze prospectively the occurrence of undesirable sequelae in patients undergoing sentinel lymph node biopsy as an isolated intervention in the axillary fossa. This prospective observational study was conducted on a group of 104 women. Patients were examined on five occasions: one day before the procedure, one day after the procedure, one month, three months, and six months after the procedure...
September 16, 2017: Pathology Oncology Research: POR
https://www.readbyqxmd.com/read/28918572/spot-light-on-skeletal-muscles-optogenetic-stimulation-to-understand-and-restore-skeletal-muscle-function
#4
Tobias van Bremen, Thorsten Send, Philipp Sasse, Tobias Bruegmann
Damage of peripheral nerves results in paralysis of skeletal muscle. Currently, the only treatment option to restore proper function is electrical stimulation of the innervating nerve or of the skeletal muscles directly. However this approach has low spatial and temporal precision leading to co-activation of antagonistic muscles and lacks cell-type selectivity resulting in pain or discomfort by stimulation of sensible nerves. In contrast to electrical stimulation, optogenetic methods enable spatially confined and cell-type selective stimulation of cells expressing the light sensitive channel Channelrhodopsin-2 with precise temporal control over the membrane potential...
September 16, 2017: Journal of Muscle Research and Cell Motility
https://www.readbyqxmd.com/read/28918556/effects-of-pregabalin-on-postoperative-pain-after-hysterectomy-under-spinal-anesthesia-with-intrathecal-morphine-a-randomized-controlled-trial
#5
Taniga Kiatchai, Vimolluck Sanansilp, Namtip Triyasunant, Sasithorn Saengprateep, Paksiree Changkittirat, Vuthinun Achariyapota
PURPOSE: To determine if preoperative pregabalin could decrease 24-h postoperative morphine consumption after spinal anesthesia with intrathecal morphine compared with placebo. METHODS: A randomized, double-blind, controlled trial was performed in the tertiary care center. Patients aged between 18 and 65 years who were American Society of Anesthesiologists class I-II and scheduled for abdominal hysterectomy with or without salpingo-oophorectomy were randomly allocated to a placebo or a pregabalin group...
September 16, 2017: Journal of Anesthesia
https://www.readbyqxmd.com/read/28918523/focal-metallic-inlay-resurfacing-prosthesis-for-the-treatment-of-localized-cartilage-defects-of-the-femoral-condyles-a-systematic-review-of-clinical-studies
#6
REVIEW
Andreas Fuchs, Helge Eberbach, Kaywan Izadpanah, Gerrit Bode, Norbert P Südkamp, Matthias J Feucht
PURPOSE: To systematically review the results of focal metallic inlay resurfacing prosthesis for the treatment of isolated cartilage defects of the femoral condyles. METHODS: A systematic electronic search of the PubMed database and the Cochrane Library was performed in April 2017 to identify studies that reported clinical or radiographic outcome of focal metallic inlay resurfacing prosthesis for the treatment of isolated cartilage defects of the femoral condyles...
September 16, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28918504/autism-spectrum-disorders-and-disease-modeling-using-stem-cells
#7
REVIEW
Anita Brito, Fabiele Baldino Russo, Alysson Renato Muotri, Patricia Cristina Baleeiro Beltrão-Braga
Autism spectrum disorders (ASD) represent a variety of disorders characterized as complex lifelong neurodevelopment disabilities, which may affect the ability of communication and socialization, including typical comportments like repetitive and stereotyped behavior. Other comorbidities are usually present, such as echolalia, hypotonia, intellectual disability and difficulties in processing figured speech. Furthermore, some ASD individuals may present certain abilities, such as eidetic memory, outstanding musical or painting talents and special mathematical skills, among others...
September 16, 2017: Cell and Tissue Research
https://www.readbyqxmd.com/read/28918499/the-levels-of-circulating-proangiogenic-factors-in-migraineurs
#8
Slawomir Michalak, Alicja Kalinowska-Lyszczarz, Danuta Wegrzyn, Anna Thielemann, Krystyna Osztynowicz, Wojciech Kozubski
Migraine has been reported as a risk factor for ischemic stroke or cardiovascular events, and dysfunction of endothelial cells has been evidenced in migraine patients. Proangiogenic factors are potential endothelial stimulators, and their disturbances can link abnormalities of endothelium with increased risk of vascular disorders. The aim of this study was to evaluate the levels of circulating proangiogenic factors in sera of migraineurs during interictal period. Fifty-two patients aged 37.9 ± 9.6 years, fulfilling International Headache Society criteria for migraine, were included in this observational case-control study...
September 16, 2017: Neuromolecular Medicine
https://www.readbyqxmd.com/read/28918450/clinical-utility-of-the-asdas-index-in-comparison-with-basdai-in-patients-with-ankylosing-spondylitis-axis-study
#9
Agustí Sellas I Fernandez, Xavier Juanola Roura, Alberto Alonso Ruiz, José Rosas, Julio Medina Luezas, Eduardo Collantes Estevez, Miguel Ángel Abad Hernández, Virginia Carrasco Benitez, Cesar Fisac
The objective of the study was to study the clinical utility of the Ankylosing Spondylitis Disease Activity Score (ASDAS) for the assessment of disease activity in ankylosing spondylitis (AS) patients, compared to the Bath Ankylosing Spondylitis Activity Index (BASDAI). This was a prospective longitudinal observational study in patients with AS (NY-modified criteria) from 23 Spanish centers. Physical and analytical data; global, lumbar, and nocturnal pain; ASDAS, BASDAI and minimally acceptable clinical status (PASS) were collected...
September 16, 2017: Rheumatology International
https://www.readbyqxmd.com/read/28918413/post-traumatic-growth-and-its-relationship-to-quality-of-life-up-to-9-years-after-liver-transplantation-a-cross-sectional-study-in-spain
#10
María Ángeles Pérez-San-Gregorio, Agustín Martín-Rodríguez, Mercedes Borda-Mas, María Luisa Avargues-Navarro, José Pérez-Bernal, Rupert Conrad, Miguel Ángel Gómez-Bravo
OBJECTIVE: Little is known concerning post-traumatic growth (PTG) after liver transplantation. Against this backdrop the current study analysed the relationship between PTG and time since transplantation on quality of life. Furthermore, it compared PTG between liver transplant recipients and their caregivers. DESIGN: Cross-sectional case-control study. SETTING: University Hospital in Spain. PARTICIPANTS: 240 adult liver transplant recipients who had undergone only one transplantation, with no severe mental disease, were the participants of the study...
September 15, 2017: BMJ Open
https://www.readbyqxmd.com/read/28918410/-just-like-a-normal-pain-what-do-people-with-diabetes-mellitus-experience-when-having-a-myocardial-infarction-a-qualitative-study-recruited-from-uk-hospitals
#11
Nikita Berman, Melvyn Mark Jones, Daan A De Coster
OBJECTIVE: The objective of the study was to investigate the symptoms people with diabetes experience when having a myocardial infarction (MI), their illness narrative and how they present their symptoms to the health service. SETTING: Three London (UK) hospitals (coronary care units and medical wards). PARTICIPANTS: Patients were recruited with diabetes mellitus (DM) (types 1 and 2) with a clinical presentation of MI (ST elevated MI (STEMI), non-ST elevated MI (NSTEMI), acute MI unspecified and cardiac arrest)...
September 15, 2017: BMJ Open
https://www.readbyqxmd.com/read/28918395/non-invasive-high-frequency-oscillatory-ventilation-in-preterm-infants-a-randomised-controlled-cross-over-trial
#12
Daniel Klotz, Hendryk Schneider, Stefan Schumann, Benjamin Mayer, Hans Fuchs
OBJECTIVE: Non-invasive high-frequency oscillatory ventilation (nHFOV) has recently been described as a novel mode of respiratory support for premature infants. This study was designed to determine whether nHFOV decreases CO2 partial pressure (pCO2) in premature infants more effectively than non-invasive continuous positive airway pressure (nCPAP). DESIGN: Non-blinded prospective randomised controlled cross-over study. SETTING: University Medical Center tertiary neonatal intensive care unit...
September 16, 2017: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/28918297/a-rare-case-of-spontaneous-rupture-of-an-aneurysm-of-the-right-gastric-artery
#13
Yu-Ki Takemoto, Nobuaki Fujikuni, Kazuaki Tanabe, Hironobu Amano, Toshio Noriyuki, Masahiro Nakahara
BACKGROUND: Visceral artery aneurysms at the origin of the gastric and gastroepiploic artery are uncommon. Raptured visceral aneurysms cause high mortality and require urgent and adequate intervention and treatment. PRESENTATION OF CASE: A 65-year-old woman was transferred to the emergency department with sudden abdominal and back pain. Radiographically, we diagnosed intra-abdominal bleeding due to a ruptured aneurysm of the right gastric artery. Although her vital signs were relatively stable, transcatheter arterial embolization (TAE) could not be performed due to thrombotic occlusion of her abdominal aorta, and bilateral axillary arteries...
September 1, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28918265/amorphous-liquid-metal-electrodes-enabled-conformable-electrochemical-therapy-of-tumors
#14
Xuyang Sun, Bo Yuan, Wei Rao, Jing Liu
Electrochemical treatment of tumors (EChT) has recently been identified as a very effective way for local tumor therapy. However, hindered by the limited effective area of a single rigid electrode, multiple electrodes are often recruited when tackling large tumors, where too many electrodes not only complicate the clinical procedures but also aggravate patients' pain. Here we present a new conceptual electric stimulation tumor therapy through introducing the injectable liquid metal electrodes, which can adapt to complex tumor shapes so as to achieve desired therapeutic performance...
September 5, 2017: Biomaterials
https://www.readbyqxmd.com/read/28918200/profiling-the-short-linear-non-disulfide-bond-containing-peptidome-from-the-venom-of-the-scorpion-tityus-obscurus
#15
Nathalia Baptista Dias, Bibiana Monson de Souza, Fernando Kamimura Cocchi, Hipócrates M Chalkidis, Valquíria Abrão Coronado Dorce, Mario Sergio Palma
Many scorpion accidents occur in the Brazilian Amazonian region and are frequently caused by Tityus obscurus. Approximately 5% of the crude venom of this species is composed of short linear, non-disulfide-bridged peptides, which have not been intensively investigated. As a consequence, only a few of these peptides have been structurally and functionally characterized to date. In the present paper, the peptide fraction of the venom was subjected to peptide profiling using an LCMS-IT-TOF/MS and MS(n) system. The analysis detected 320 non-disulfide bond-containing peptides (NDBPs), of which twenty-seven had their sequences assigned; among them, thirteen peptides were characterized, constituting novel toxins in T...
September 13, 2017: Journal of Proteomics
https://www.readbyqxmd.com/read/28918191/development-and-validation-of-a-chronic-pancreatitis-prognosis-score-in-2-independent-cohorts
#16
Georg Beyer, Ujjwal M Mahajan, Christoph Budde, Thomas J Bulla, Thomas Kohlmann, Louise Kuhlmann, Kerstin Schütte, Ali A Aghdassi, Eckhard Weber, Ulrich Weiss, Asbjørn M Drewes, Søren S Olesen, Markus M Lerch, Julia Mayerle
BACKGROUND & AIMS: The clinical course of chronic pancreatitis is unpredictable. There is no model to assess disease severity or progression or predict patient outcomes. METHODS: We performed a prospective study of 91 patients with chronic pancreatitis; data were collected from patients seen at academic centers in Europe, from January 2011 through April 2014. We analyzed correlations between clinical, laboratory, and imaging data with number of hospital readmissions and in-hospital days over the next 12 months; the parameters with the highest degree of correlation were to develop 3-stage chronic pancreatitis prognosis score (COPPS)...
September 14, 2017: Gastroenterology
https://www.readbyqxmd.com/read/28918186/health-related-quality-of-life-in-melanoma-patients-impact-of-melanoma-related-limb-lymphoedema
#17
Caroline A Gjorup, Mogens Groenvold, Helle W Hendel, Karin Dahlstroem, Krzysztof T Drzewiecki, Tobias W Klausen, Lisbet R Hölmich
AIM: To explore health-related quality of life (HRQoL) in recurrence-free melanoma patients, with a focus on the association between melanoma-related limb lymphoedema and HRQoL. METHODS: HRQoL was evaluated using the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30), the breast cancer module (EORTC QLQ-BR23) subscales body image and future perspective, the Functional Assessment for Cancer Therapy-General subscale social/family well-being and the Hospital Anxiety and Depression Scale...
September 14, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28918182/uk-temporomandibular-joint-replacement-database-a-report-on-one-year-outcomes
#18
R Elledge, A Attard, J Green, D Lowe, S N Rogers, A J Sidebottom, B Speculand
Alloplastic temporomandibular joint (TMJ) replacements are increasingly subspecialised, and supraregional centres that treat sufficient numbers to ensure high standards are emerging. Having recently reported the introduction of a national TMJ joint replacement database that is endorsed by the British Association of TMJ Surgeons (BATS), we now present the first-year outcomes. This was a review of all data in the BATS National Case Registration of TMJ Replacement as of June 2014. A total of 252 one-year outcome records were available...
September 13, 2017: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/28918147/invited-review-effects-of-heat-stress-on-dairy-cattle-welfare
#19
Liam Polsky, Marina A G von Keyserlingk
The effects of high ambient temperatures on production animals, once thought to be limited to tropical areas, has extended into northern latitudes in response to the increasing global temperature. The number of days where the temperature-humidity index (THI) exceeds the comfort threshold (>72) is increasing in the northern United States, Canada, and Europe. Compounded by the increasing number of dairy animals and the intensification of production, heat stress has become one of the most important challenges facing the dairy industry today...
September 13, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28918127/clinical-laboratory-and-virological-data-from-suspected-zikv-patients-in-an-endemic-arbovirus-area
#20
Tatiana Elias Colombo, Cássia Fernanda Estofolete, Andréia Francesli Negri Reis, Natal Santos da Silva, Morgana Lima Aguiar, Eliana Márcia Sotello Cabrera, Izalco Nuremberg Penha Dos Santos, Fabiana Rodrigues Costa, Lilian Elisa Arão Antônio Cruz, Patrícia Lopes Rombola, Ana Carolina Bernardes Terzian, Maurício Lacerda Nogueira
BACKGROUND: The emergence of Zika virus (ZIKV) presents new challenges to both clinicians and public health authorities. Overlapping clinical features between the diseases caused by ZIKV, dengue (DENV) and chikungunya (CHIKV) and the lack of validated serological assays for ZIKV make accurate diagnosis difficult. Brazilian authorities largely rely on clinical and epidemiological data for the epidemiological and clinical classifications of most ZIKV cases. OBJECTIVE: To report the laboratory and clinical profiles of patients diagnosed with Zika fever based only on clinical and epidemiological data...
September 9, 2017: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
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