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https://www.readbyqxmd.com/read/29334669/anti-obesity-effects-of-clausena-excavata-in-high-fat-diet-induced-obese-mice
#1
Young-Rak Cho, Jung A Lee, Yoon Yeon Kim, Jae-Shin Kang, Jae-Ho Lee, Eun-Kyung Ahn
Clausena excavata (C. excavata) has been used as a traditional medicine for the treatment of abdominal pain, enteritis, dysentery, and malaria. The present study was designed to evaluate the effect of a 50% ethanol extract of C. excavata (ECE) on weight loss, adipocyte size, and obesity-related biochemical parameters in high-fat diet (HFD)-induced obese mice. After 6 weeks of HFD + ECE administration, HFD-induced total fat, subcutaneous fat, and visceral fat were evaluated by micro-computed tomography. The serum levels of triglyceride (TG), total cholesterol (TCH), high-density lipoprotein (HDL) cholesterol, and low-density lipoprotein (LDL) cholesterol were evaluated with a biochemical analyzer, and leptin and adiponectin levels in the serum were assessed via enzyme-linked immunoassay (ELISA)...
January 12, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29334573/-a-fresh-cadaver-study-on-indocyanine-green-fluorescence-lymphography-a-new-whole-body-imaging-technique-for-investigating-the-superficial-lymphatics
#2
Akira Shinaoka, Seijiro Koshimune, Kiyoshi Yamada, Kanae Kumagishi, Hiroo Suami, Yoshihiro Kimata, Aiji Ohtsuka
BACKGROUND: Identification of the lymphatic system in cadavers is painstaking because lymphatic vessels have very thin walls and are transparent. Selection of appropriate contrast agents is a key factor for successfully visualizing the lymphatics. In this study, we introduce a new imaging technique of lymphatic mapping in whole body of fresh cadavers. METHODS: Ten fresh human cadavers were used for this study. We injected 0.1 mL of indocyanine green fluorescence (ICG) solution subcutaneously at multiple spots along the watershed lines between lymphatic territories and hand and foot regions...
January 10, 2018: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29334531/dangerously-numb-opioids-benzodiazepines-chronic-pain-and-posttraumatic-stress-disorder
#3
Mark Sullivan
No abstract text is available yet for this article.
December 6, 2017: Pain
https://www.readbyqxmd.com/read/29334520/invited-commentary-evaluation-of-horner-syndrome-in-the-mri-era
#4
Aki Kawasaki
This Invited Commentary discusses the following article: BACKGROUND:: To identify the etiologies of adult Horner syndrome (HS) in the MRI era using a targeted evaluation approach and to assess the value and yield of targeted imaging. METHODS: A retrospective chart review was performed of 200 adult outpatients with HS, confirmed with cocaine eyedrop testing. Patients were divided into subgroups based on the presence or absence of symptoms and those who did or did not receive additional testing with hydroxyamphetamine drops...
January 11, 2018: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/29334519/the-most-common-causes-of-eye-pain-at-2-tertiary-ophthalmology-and-neurology-clinics
#5
Randy C Bowen, Jan N Koeppel, Chance D Christensen, Karisa B Snow, Junjie Ma, Bradley J Katz, Howard R Krauss, Klara Landau, Judith E A Warner, Alison V Crum, Dominik Straumann, Kathleen B Digre
BACKGROUND: Eye pain is a common complaint, but no previous studies have determined the most common causes of this presenting symptom. Our objective was to determine the most common causes of eye pain in 2 ophthalmology and neurology departments at academic medical centers. METHODS: This was a retrospective cross-sectional analysis and chart review at the departments of ophthalmology and neurology at the University Hospital Zurich (USZ), University of Zürich, Switzerland, and the University of Utah (UU), USA...
January 12, 2018: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/29334518/is-ileocecal-valve-intubation-essential-for-routine-colonoscopic-examination
#6
Murat Meral, Göksel Bengi, Hasan Kayahan, Mesut Akarsu, Müjde Soytürk, Ömer Topalak, Hale Akpinar, Özgül Sağol
BACKGROUND: In this study, we aimed to assess the diagnostic yield of terminal ileum intubation during routine colonoscopy. MATERIALS AND METHODS: We routinely performed terminal ileum intubation in all patients who underwent colonoscopy at Dokuz Eylul University Hospital between February 2014 and June 2015. Two gastroenterology fellows performed colonoscopies in the Central Endoscopy Unit. Demographic data of patients, indications of colonoscopies, cecum and ileum intubation rate/time, and endoscopic and histopathologic findings of the terminal ileum were all assessed...
January 12, 2018: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29334505/the-association-of-chronic-air-pollutants-with-coronary-artery-spasm-vasospastic-angina-and-endothelial-dysfunction
#7
Byoung Geol Choi, Jiwon Lee, Suhng Wook Kim, Min Woo Lee, Man Jong Baek, Yang Gi Ryu, Se Yeon Choi, Jae Kyeong Byun, Ahmed Mashaly, Yoonjee Park, Won Young Jang, Woohyeun Kim, Jah Yeon Choi, Eun Jin Park, Jin Oh Na, Cheol Ung Choi, Hong Euy Lim, Eung Ju Kim, Chang Gyu Park, Hong Seog Seo, Dong Joo Oh, Seung-Woon Rha
BACKGROUND: We evaluated the effect of chronic exposure to air pollutants (APs) on coronary endothelial function and significant coronary artery spasm (CAS) as assessed by intracoronary acetylcholine (ACH) provocation test. PATIENTS AND METHODS: A total of 6430 patients with typical or atypical chest pain who underwent intracoronary ACH provocation test were enrolled. We obtained data on APs from the Korean National Institute of Environmental Research (http://www...
January 12, 2018: Coronary Artery Disease
https://www.readbyqxmd.com/read/29334500/overexpression-of-%C3%A2%C2%B5-opioid-receptors-in-peripheral-afferents-but-not-in-combination-with-enkephalin-decreases-neuropathic-pain-behavior-and-enhances-opioid-analgesia-in-mouse
#8
Amanda H Klein, Husam K Mohammad, Rabiah Ali, Brad Peper, Steven P Wilson, Srinivasa N Raja, Matthias Ringkamp, Sarah Sweitzer
BACKGROUND: The current study used recombinant herpes simplex virus type I to increase expression of µ-opiate receptors and the opioid ligand preproenkephalin in peripheral nerve fibers in a mouse model of neuropathic pain. It was predicted that viral vector delivery of a combination of genes encoding the µ-opioid receptor and preproenkephalin would attenuate neuropathic pain and enhance opioid analgesia. The behavioral effects would be paralleled by changes in response properties of primary afferent neurons...
January 15, 2018: Anesthesiology
https://www.readbyqxmd.com/read/29334488/severe-intraocular-pressure-elevation-after-intracameral-healon-5-viscoelastic-support-for-post-operative-hypotony-after-xen-gel-stent-insertion
#9
Alice Bruynseels, Freda Sii, Imran Masood, Peter Shah
PURPOSE: To describe (i) a novel case of severe intraocular pressure (IOP) elevation due to intracameral Healon 5 for management of early post-operative hypotony following XEN Gel Stent insertion and (ii) the management of this complication. METHODS: A case report. RESULTS: A 52-year-old male, with primary open angle glaucoma and suboptimal left IOP control on maximally tolerated medical therapy, was managed with XEN Gel Stent insertion at another tertiary eye unit...
January 12, 2018: Journal of Glaucoma
https://www.readbyqxmd.com/read/29334327/migration-of-a-kirschner-wire-into-the-spinal-cord-a-case-report-and-literature-review
#10
Ryogo Furuhata, Mitsuhiro Nishida, Midori Morishita, Shigeru Yanagimoto, Masaki Tezuka, Eijiro Okada
CONTEXT: A Kirschner wire (K-wire) is a stainless steel pin with at least one sharpened tip that is mainly used for the internal fixation of bone fractures. While some cases of K-wire dislocation and migration have been reported as complications after fracture surgery, the intraspinal migration of a K-wire is rare. Herein, we report a case in which a K-wire used for sternal fixation 7 years earlier migrated into the spinal canal. FINDINGS: A 68-year-old male suddenly sustained severe radiating pain and numbness in his left upper extremity, and walked to our hospital...
January 15, 2018: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/29334308/neuromuscular-degenerative-effects-of-ankaferd-blood-stopper%C3%A2-in-mouse-sciatic-nerve-model
#11
Ramazan Üstün, Elif Kaval Oğuz, Çağrı Delilbaşı, Ayşe Şeker, Filiz Taşpınar, Mehmet Reşit Öncü, Ahmet Regaip Oğuz
Purpose Ankaferd Blood Stopper® (ABS), a licenced medicinal herbal extract, is commonly used as an effective topical haemostatic agent. This study is designed to investigate whether topical ABS application may cause peripheral nerve degeneration and neuromuscular dysfunction in a mouse sciatic nerve model. Methods Twenty mice were randomly divided into two groups; an ABS treated experimental group and a saline-treated control group. Left sciatic nerves were treated with 0.3 ml of ABS in the experimental group and 0...
January 15, 2018: Somatosensory & Motor Research
https://www.readbyqxmd.com/read/29334292/safety-and-effectiveness-of-fascial-therapy-in-adult-patients-with-hemophilic-arthropathy-a-pilot-study
#12
Elena Donoso-Úbeda, Javier Meroño-Gallut, José Antonio López-Pina, Rubén Cuesta-Barriuso
BACKGROUND: The primary clinical manifestations of hemophilia are muscle and joint bleeding. Recurrent bleeding leads to a degenerative process known as hemophilic arthropathy. Fascial therapy is one of the most used physiotherapy techniques today to improve joint dysfunctions and chronic pain. OBJECTIVE: To assess the safety and efficacy of fascial therapy treatment in patients with hemophilic arthropathy of ankle and knee. DESIGN: Non-randomized, controlled clinical trial...
January 15, 2018: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29334290/topical-lidocaine-prilocaine-cream-versus-lidocaine-infiltration-for-pain-relief-during-repair-of-perineal-tears-after-vaginal-delivery-randomized-clinical-trial
#13
Ahmed M Abbas, Hamida A Abdel Hafiz, Aya M Abdelhafez, Armia Michael, Alaa M Ismail
OBJECTIVE: The current study aims to compare the analgesic effect of lidocaine-prilocaine (LP) cream with lidocaine infiltration during repair of perineal tears after vaginal delivery. MATERIALS AND METHODS: A single center open-labeled randomized clinical trial was carried out in a tertiary University Hospital between October 2016 and May 2017 (Clinical Trials.Gov: NCT02883179). We included parous women delivered at gestational age > 37 weeks with first or second degree perineal tears...
January 15, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29334276/an-automatic-measure-of-progression-during-colonoscopy-correlates-to-patient-experienced-pain
#14
Louise Preisler, Mustafa Bulut, Morten Soendergaard Svendsen, Lars Bo Svendsen, Lars Konge
BACKGROUND: Colonoscopy screening and surveillance programs depend on patient's tolerable experience, which is associated with competence of the endoscopist. The Colonoscopy Progression Score (CoPS) is an automated tool based on recording of the Magnetic Scope Imager (MEI) picture in order to track progression. CoPS deliver a numeric score and a graphic map. A high score expresses a rapid and smooth progression. Aims of study were to explore the correlation between CoPS and patient experienced pain and to identity locations associated with pain...
January 15, 2018: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29334260/crude-extract-of-origanum-vulgare-l-induced-cell-death-and-suppressed-mapk-and-pi3-akt-signaling-pathways-in-sw13-and-h295r-cell-lines
#15
Beatrice Rubin, Jacopo Mansi, Halenya Monticelli, Loris Bertazza, Marco Redaelli, Francesca Sensi, Maira Zorzan, Carla Scaroni, Caterina Mian, Maurizio Iacobone, Decio Armanini, Cristina Bertolini, Susi Barollo, Marco Boscaro, Raffaele Pezzani
Oregano (Origanum vulgare L.) is a common aromatic plant used in Mediterranean and Asian Regions for treating respiratory diseases, painful menstruation, rheumatoid arthritis, etc. Recently its role as an anticancer plant has been suggested, although oregano has been never evaluated into adrenocortical tumour cell models. This study analysed for the first time the anticancer effects of a crude extract of wild mountain oregano (Origanum vulgare L.) in SW13 and H295R cell lines. The crude extract was characterised by GC/MS and the toxic effects of oregano were first analysed by brine shrimp lethality assay...
January 15, 2018: Natural Product Research
https://www.readbyqxmd.com/read/29334204/detection-of-chlamydia-trachomatis-in-pap-smear-samples-from-south-khorasan-province-of-iran
#16
Davod Javanmard, Mahmoodreza Behravan, Malaknaz Ghannadkafi, Alireza Salehabadi, Masood Ziaee, Mohammad Hasan Namaei
Background: Chlamydia trachomatis (CT), the most common bacterial sexually transmitted infection (STI), leads to pelvic inflammatory disease, infertility and chronic pelvic pain in women as well as an increased risk of vertical transmission, conjunctivitis and pneumonitis in infants. It may also be a co-factor along with human papillomavirus (HPV) in cervical cancer progression. We aimed to determine the prevalence of CT genotypes in genital specimens of women from South Khorasan, Iran and to test the association between CT and cytology statistics...
April 2018: International Journal of Fertility & Sterility
https://www.readbyqxmd.com/read/29334174/trichloroacetic-acid-80-as-a-chemical-debridement-method-for-chronic-venous-leg-ulcers-a-pilot-study
#17
Rita R Pinheiro, Bruno Duarte, Joana Cabete
Debridement is essential for the optimal care of venous leg ulcers. Several debridement methods with different limitations may be deployed. Trichloroacetic acid (TCA) is used for several dermatological purposes. Its application as a chemical debridement method for leg ulcers has never been explored. We designed a prospective study to determine the role of 80% TCA solution as a chemical debridement method for leg ulcers, regarding efficacy and procedure-associated pain. Chronic venous leg ulcers were treated with 3 cycles of 80% TCA solution or curettage over 1 week...
January 15, 2018: International Wound Journal
https://www.readbyqxmd.com/read/29334136/a-bayesian-network-meta-analysis-efficacy-of-air-insufflation-co2-insufflation-water-exchange-and-water-immersion-in-colonoscopy
#18
REVIEW
Zhen Zhang, Yifeng Wu, Guangge Sun, Jing Zhang, Jiaxin Li, Chongyang Qiu, Xin Zheng, Botao Wang, Lei Yang, Ximo Wang
BACKGROUND: Colonoscopy is one of the excellent tools for screening colorectal cancer. There were four colonoscopy techniques containing air insufflation, CO2 insufflation, water exchange, and water immersion. Some studies reported that these methods are better than the criterion standard (air insufflation), while some studies showed not. In order to evaluate the efficacy of four colonoscopy techniques, a network meta-analysis was performed in present study. METHODS: We searched randomized controlled trials (RCTs) published up to September 2017 from PubMed, Embase, Cochrane library, and Web of Science...
January 15, 2018: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/29334040/botulinum-toxin-type-a-for-pain-in-advanced-parkinson-s-disease
#19
Veronica Bruno, Maria Eliza Freitas, Deborah Mancini, Jane P Lui, Janis Miyasaki, Susan H Fox
Background and Objective Pain is a frequent symptom in Parkinson's disease (PD), and the therapeutic alternatives are scarce. The goal of this trial was to measure the effects of botulinum toxin type A (BTXA) in the treatment of limb pain in advanced PD. Methods A randomized double-blind crossover versus placebo study of BTXA for limb pain in advanced Parkinson's disease was conducted. Subjects received individualized BTXA/placebo dosing per pain distribution in limbs. The primary outcome was a measure of change in global pain on a numeric rating scale (NRS) at 4 and 12 weeks postinjection and on a visual analogue scale 12 weeks after treatment...
January 2018: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/29333991/evaluation-of-a-portable-gas-chromatograph-with-photoionization-detector-under-variations-of-voc-concentration-temperature-and-relative-humidity
#20
Jhy-Charm Soo, Eun Gyung Lee, Ryan F LeBouf, Michael L Kashon, William Chisholm, Martin Harper
The objective of this present study was to evaluate the performance of a portable gas chromatograph ─ photoionization detector (GC-PID), under various test conditions to determine if it could be used in occupational settings. A mixture of seven volatile organic compounds (VOCs) - acetone, ethylbenzene, methyl isobutyl ketone, toluene, m-xylene, p-xylene, and o-xylene - was selected because its components are commonly present in paint manufacturing industries. A full-factorial combination of four concentration levels (exposure scenarios) of VOC mixtures, three different temperatures (25˚C, 30˚C, and 35˚C), and three relative humidities (RHs; 25%, 50%, and 75%) was conducted in a full- size controlled environmental chamber...
January 15, 2018: Journal of Occupational and Environmental Hygiene
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