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Donor management

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https://www.readbyqxmd.com/read/29166375/gastric-emptying-of-different-meal-volumes-of-identical-composition-in-preterm-infants-a-time-series-analysis
#1
Sharon L Perrella, Anna R Hepworth, Zoya Gridneva, Karen N Simmer, Peter E Hartmann, Donna T Geddes
BACKGROUND: Preterm infants' meals typically progress to higher volumes over time. Knowledge of gastric emptying (GE) responses to differing meal volumes may inform enteral feeding management. We examined the effect of meal volume and composition on preterm GE. METHODS: Forty infants were studied at 33.3±1.4 (29.7-35.6) weeks postmenstrual age when fully enteral fed (target 150 ml/kg/day). Intra-individual comparisons of GE were made for paired meals of 100 and 75% prescribed volume and identical composition of mother's own milk (n=21) and pasteurized donor human milk (n=19)...
November 22, 2017: Pediatric Research
https://www.readbyqxmd.com/read/29166306/the-surgical-management-of-nerve-gaps-present-and-future
#2
Samer Bassilios Habre, Grant Bond, Xi Lin Jing, Epameinondas Kostopoulos, Robert D Wallace, Petros Konofaos
Peripheral nerve injuries can result in significant morbidity, including motor and/or sensory loss, which can affect significantly the life of the patient. Nowadays, the gold standard for the treatment of nerve section is end-to-end neurorrhaphy. Unfortunately, in some cases, there is segmental loss of the nerve trunk. Nerve mobilization allows primary repair of the sectioned nerve by end-to-end neurorrhaphy if the gap is less than 1 cm. When the nerve gap exceeds 1 cm, autologous nerve grafting is the gold standard of treatment...
November 21, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29160012/near-infrared-spectroscopy-might-be-a-useful-tool-for-predicting-the-risk-of-vascular-complications-after-pediatric-liver-transplants-two-case-reports
#3
Juntaro Shiba, Masaaki Satoh, Koki Taira, Yasunori Niwa, Soichiro Inoue, Koichi Mizuta, Mamoru Takeuchi
In patients that have undergone liver transplants, a postoperative reduction in the blood flow of the liver graft represents a critical complication. We recently encountered an interesting phenomenon; that is, we found that the rSO2 level of the liver graft, as measured by NIRS, drops in patients that subsequently require an emergency liver biopsy. An 8-month-old female and an 8-month-old male underwent living donor liver transplants for biliary atresia. In both cases, a reduction in rSO2 was detected before an emergency liver biopsy was required...
November 21, 2017: Pediatric Transplantation
https://www.readbyqxmd.com/read/29158064/mirna-223-functions-as-both-prognostic-biomarker-and-tumor-suppressor-in-mantle-cell-lymphoma-through-targeting-sox11
#4
REVIEW
Keshu Zhou, Xiaoyan Feng, Yanying Wang, Yanyan Liu, Long Tian, Wenli Zuo, Shuhua Yi, Xudong Wei, Yongping Song, Lugui Qiu
Mantle cell lymphoma (MCL) is an aggressive lymphoid malignance characterized by cytogenetic aberration of t(11;14), although it is not the prerequisite. Until now, the pathogenesis of MCL remains not fully interpreted. Our current study showed that miR-223 was down-regulated in purified CD19+ lymphocytes from MCL patients (n=21) compared with that of normal donors (n=20). In addition, patients with high-risk mantle international prognostic index, elevated LDH, performance status>2 were more likely to have much lower miR-223 expression...
November 17, 2017: Experimental Hematology
https://www.readbyqxmd.com/read/29156161/the-use-of-particulated-juvenile-allograft-cartilage-in-foot-and-ankle-surgery
#5
REVIEW
Alan Ng, Kaitlyn Bernhard
Particulated juvenile allograft cartilage (PJAC) has significant promise and is currently supported by several studies. Potential benefits of this new technique include single-stage procedure, simplicity in the surgical technique, implantation of juvenile tissue, and a lack of donor site morbidity. This article discusses the imaging, surgical options, and postoperative management of PJAC.
January 2018: Clinics in Podiatric Medicine and Surgery
https://www.readbyqxmd.com/read/29153255/-management-of-hypopigmented-scars-following-burn-injuries
#6
M Schmidt, K Serror, M Chaouat, M Mimoun, D Boccara
OBJECTIVE: Permanent hypopigmentation of burn scars is a common consequence after partial and full thickness burns that heal by secondary intent, and they can cause severe aesthetic issues. The surgical goals for effective treatment of postburn hypopigmentation are to remove scar tissues, and to produce healthy melanocytes, with minimal donor site morbidity. This article reviews the current literature about the different ways to treat hypopigmentation following burn injuries and discusses the indications...
November 15, 2017: Annales de Chirurgie Plastique et Esthétique
https://www.readbyqxmd.com/read/29149952/financial-impact-of-incidental-radiologic-findings-during-living-kidney-donor-evaluation
#7
A Mutneja, L Saling, M Yano, A Vijayan
Living kidney donor (LKD) transplantation is an important alternative for the end-stage renal disease population and is preferred due to superior outcomes when compared with dialysis or deceased donor transplantation. LKD evaluation includes a computed tomography angiogram (CTA) for assessment of renal and renovascular anatomy. Incidental nonrenal findings are frequently noted during the CTAs, and these may have variable clinical significance. These incidental findings lead to further testing, procedures, and referrals, which incur additional cost...
November 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/29149951/predictive-factors-of-renal-adaptation-after-nephrectomy-in-kidney-donors
#8
H J Kwon, D H Kim, H R Jang, S-H Jung, D H Han, H H Sung, J B Park, J E Lee, W Huh, S J Kim, Y-G Kim, D J Kim, H Y Oh
BACKGROUND: Despite compensatory hyperfiltration in remaining nephrons following donor nephrectomy, some donors show impaired renal adaptation and low estimated glomerular filtration rate (eGFR). We investigated the factors predicting early renal adaptation after nephrectomy and identified kidney donors at risk of inadequate renal adaptation. METHODS: A total of 265 living kidney donors from 2010 to 2013 were retrospectively analyzed. Renal function was serially followed for 6 months after the operation...
November 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/29148259/vasovagal-reactions-in-blood-donors-risks-prevention-and-management
#9
REVIEW
A Thijsen, B Masser
This narrative review examines current research on risk factors, prevention methods and management strategies for vasovagal reactions (VVRs) that occur during or as a result of blood donation. VVRs are important to blood collection agencies (BCAs) as they negatively impact the number of completed collections, perceptions of the safety of blood donation and rates of donor return. There has been significant progress in understanding and preventing VVRs in blood donation in recent years, with a multitude of risk factors identified...
November 16, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/29144926/re-telemedically-supported-case-management-of-living-donor-renal-transplant-recipients-to-optimize-routine-evidence-based-aftercare-a-single-center-randomized-controlled-trial
#10
https://www.readbyqxmd.com/read/29143343/secrets-and-disclosure-in-donor-conception
#11
Lucy Frith, Eric Blyth, Marilyn Crawshaw, Olga van den Akker
This article considers the disclosure, sharing and exchange of information on being donor conceived within families, drawing on data from a study undertaken with donor-conceived adults registered with UK Donor Link (a voluntary DNA-linking register). This paper considers the narratives of how respondents found out they were donor-conceived and what events triggered disclosure of this information. This paper then goes on to examine the role secrecy played in their family life and uses the concept of 'display' to explore how secrecy affected their relationships with their immediate and extended family...
November 16, 2017: Sociology of Health & Illness
https://www.readbyqxmd.com/read/29142490/postoperative-elevated-resistive-indices-do-not-predict-hepatic-artery-thrombosis-in-extended-criteria-donor-livers
#12
Eric J Siskind, Fauzia Vandermeer, Tamar R Siskind, David A Bruno, Samuel Sultan, Josue Alvarez-Casas, Arielle Stafford, Barton Lane, John C Lamattina, Rolf N Barth, Steven I Hanish
Postoperative transplant liver ultrasounds were analyzed in standard criteria donor (SCD), extended criteria donor (ECD), and donation after cardiac death (DCD) liver allografts to determine if elevated resistive indices (RIs) are consistently present and if they are pathological. Postoperative transplant liver ultrasounds were reviewed from 115 consecutive patients. Hepatic arterial RIs were stratified based on the type of donor: DCD, macrosteatosis (>30%), or standard criteria. In all patients with elevated RI, subsequent ultrasounds were reviewed to demonstrate RI normalization...
December 2017: International Journal of Angiology: Official Publication of the International College of Angiology, Inc
https://www.readbyqxmd.com/read/29137595/study-of-bacterial-infections-among-patients-receiving-kidney-transplant-in-mashhad-iran
#13
Davood Mansury, Azad Khaledi, Kiarash Ghazvini, Mahin Ghorban Sabbagh, Hosna Zare, Mohammad Hossein Rokni-Hosseini, Hossein Vazini
OBJECTIVES: Over the past 2 decades, significant advances have been made in the management of infections after transplant; however, transplant recipients are still at high risk of infectious complications. This study aimed to evaluate the prevalence of bacterial infections and antimicrobial resistance patterns in kidney transplant recipients. MATERIALS AND METHODS: This cross-sectional study included 356 patients who received kidney transplants, regardless of the underlying disease, from 2013 to 2015 at the Montaserieh Transplant Hospital (Mashhad, Iran)...
November 15, 2017: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/29137513/trends-in-the-alignment-and-harmonization-of-reproductive-maternal-newborn-and-child-health-funding-2008-13
#14
Melisa Martinez-Alvarez, Arnab Acharya, Leonardo Arregoces, Lara Brearley, Catherine Pitt, Christopher Grollman, Josephine Borghi
Donor financing to low- and middle-income countries for reproductive, maternal, newborn, and child health increased substantially from 2008 to 2013. However, increased spending by donors might not improve outcomes, if funds are delivered in ways that undermine countries' public financial management systems and incur high transaction costs for project implementation. We combined quantitative and qualitative methods to examine the quality of funding for reproductive, maternal, newborn, and child health globally and in Tanzania, based on two principles of aid effectiveness: the alignment of donor financing with the recipient country's public health financial management systems, and donor harmonization for coordinated, transparent, and collectively effective actions...
November 2017: Health Affairs
https://www.readbyqxmd.com/read/29130558/right-lobe-donor-hepatectomy-is-it-safe
#15
Sanjay Goja, Sanjay Kumar Yadav, Sanjiv Saigal, Arvinder Singh Soin
INTRODUCTION: Donor safety is utmost important in Living donor liver transplantation (LDLT). Small for size syndrome in some recipients with left lobe donors led to the evolution of right lobe LDLT. AIM: To analyse the safety of large series of right lobe (RL) donor hepatectomies and compare outcomes with left lobe (LL) and left lateral segment (LLS) donations. MATERIAL AND METHODS: A consecutive cohort of 726 donors from January 2011 to January 2014 were studied; RL (n=641, 88...
November 12, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/29128085/-hla-coding-in-promise-guidelines-from-the-francophone-society-of-bone-marrow-transplantation-and-cellular-therapy-sfgm-tc
#16
Nicole Raus, Catherine Faucher, Anne Kennel, Maguy Pereira, Cécile Veron, Ibrahim Yakoub-Agha, Pascale Loiseau
As part of the 7th Annual francophone workshop series on the harmonization of clinical practices in allogeneic stem cell transplantation held in Lille in September 2016, our workgroup discussed how transplant centers might follow a collective approach to coding data. This was done mainly by analyzing the study results found in the literature that do not provide clear answers. In addition, we discuss practical ways of coding for both donor and recipient HLA typing in the European bone marrow transplantation database called ProMISe which is managed by the European Society for Blood and Marrow Transplantation (EBMT)...
November 8, 2017: Bulletin du Cancer
https://www.readbyqxmd.com/read/29128023/evaluation-and-management-of-the-potential-lung-donor
#17
REVIEW
Andrew Courtwright, Edward Cantu
The expansion of the donor lung pool has involved an evidence-driven redefinition of acceptable donors. Proceeding with transplantation with an acceptable rather than ideal donor depends on specific patient-related and organ-related risk factors as well as the severity of recipient illness. Although the physiologic optimization of brain-dead donors has not changed significantly in recent years, the use of donor management protocols has improved procurement rates. Ex vivo lung perfusion is an increasingly viable strategy to recondition lungs that would otherwise fall below the acceptable threshold for transplant...
December 2017: Clinics in Chest Medicine
https://www.readbyqxmd.com/read/29127678/allogeneic-matched-related-transplantation-for-%C3%AE-thalassemia-and-sickle-cell-anemia
#18
Françoise Bernaudin, Corinne Pondarré, Claire Galambrun, Isabelle Thuret
Allogeneic hematopoietic stem cell transplantation (HSCT) can cure single gene disorders such as thalassemia and sickle cell anemia (SCA). These non-malignant diseases have in common severe hemolytic anemia and high proliferative bone marrow, requiring frequent transfusions. The risk of rejection is high and graft-vs-host disease is not desirable. Important progress has been made in the management of these diseases, including leukocyte depletion of blood products, and chelation therapy, for both diseases, and erythrocytapheresis and hydroxycarbamide for SCA...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29126680/anesthetic-and-perioperative-considerations-for-combined-heart-kidney-transplantation
#19
Santiago Mc Loughlin, Juan C Bianco, Ricardo G Marenchino
OBJECTIVE: To describe detailed perioperative features of combined heart and kidney transplant (HKT). DESIGN: Retrospective study. SETTING: Tertiary care university hospital. PARTICIPANTS: All consecutive HKT recipients aged 18 years and older. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: After approval of the Institutional Review Board, the authors studied all consecutive adult patients who underwent HKT between January 2013 and July 2016...
September 15, 2017: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29118534/pure-retroperitoneoscopic-donor-nephrectomy-in-duplication-of-inferior-vena-cava-a-series-of-four-cases
#20
Bipin Chandra Pal, Pranjal R Modi, Syed Jamal Rizvi, Rohit Chauhan, Suresh Kumar, Shruti P Gandhi, Vivek B Kute, Hargovind L Trivedi
Aim: Complex vascular anatomy poses a major challenge to the donor surgeon. Here, we have described the technical nuances in retroperitoneoscopic living donor nephrectomy for the left kidney in the situations of a rare vascular anomaly of duplication of inferior vena. Materials and Methods: Between September 2005 and June 2016, 1460 retroperitoneoscopic living donor nephrectomy were carried out in single surgical unit of our institution. Out of these four donors were found to have duplication of inferior vena cava (IVC)...
October 2017: Urology Annals
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