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https://www.readbyqxmd.com/read/28931261/carotid-endarterectomy-in-patients-with-thrombocytopenia-analysis-of-the-national-surgical-quality-improvement-program-registry
#1
Adnan I Qureshi, Aiman Zafar, Muhammad Shah Miran, Vishal B Jani
BACKGROUND: Carotid endarterectomy (CEA) is infrequently performed in patients with mild to moderate thrombocytopenia. OBJECTIVE: To determine whether preoperative thrombocytopenia is associated with a higher rate of complications after CEA. METHODS: We analyzed patient characteristics, comorbid conditions, operative details, and 30-day postoperative outcomes for patients who underwent CEA in the CEA-targeted American College of Surgeons National Surgical Quality Improvement Program Registry...
February 1, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/28931034/primary-care-physicians-are-under-testing-for-celiac-disease-in-patients-with-iron-deficiency-anemia-results-of-a-national-survey
#2
Marisa Spencer, Adrienne Lenhart, Jason Baker, Joseph Dickens, Arlene Weissman, Andrew J Read, Seema Saini, Sameer D Saini
BACKGROUND: Iron deficiency anemia (IDA) is a common extra-intestinal manifestation of celiac disease (CD). Little is known about the frequency with which primary care physicians (PCPs) test for CD in patients with IDA. We aimed to describe how PCPs approach testing for CD in asymptomatic patients with IDA. METHODS: We electronically distributed a survey to PCPs who are members of the American College of Physicians. Respondents were asked whether they would test for CD (serologic testing, refer for esophagogastroduodenoscopy [EGD], or refer to GI) in hypothetical patients with new IDA, including: (1) a young Caucasian man, (2) a premenopausal Caucasian woman, (3) an elderly Caucasian man, and (4) a young African American man...
2017: PloS One
https://www.readbyqxmd.com/read/28930960/prehospital-administration-of-freeze-dried-plasma-is-it-the-solution-for-trauma-casualties
#3
Amir Shlaifer, Maya Siman-Tov, Irina Radomislensky, Kobi Peleg, Avi Shina, Erez Nachum Baruch, Elon Glassberg, Avraham Yitzhak
BACKGROUND: Hemorrhage is the leading cause of possible preventable death in the battlefield. There is an increasing evidence for the effectiveness of blood component therapy in general, and plasma infusion in particular but their use is less applicable in the prehospital setting due to logistic difficulties. Israeli Defense Force has implemented the use of freeze-dried plasma (FDP) at the point of injury (POI), this adoption of FDP use entailed doubts regarding the feasibility and effectiveness of this practice...
October 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28930959/outcomes-after-concomitant-traumatic-brain-injury-and-hemorrhagic-shock-a-secondary-analysis-from-the-pragmatic-randomized-optimal-platelets-and-plasma-ratios-trial
#4
Samuel M Galvagno, Erin E Fox, Savitri N Appana, Sarah Baraniuk, Patrick L Bosarge, Eileen M Bulger, Rachel A Callcut, Bryan A Cotton, Michael Goodman, Kenji Inaba, Terence O'Keeffe, Martin A Schreiber, Charles E Wade, Thomas M Scalea, John B Holcomb, Deborah M Stein
BACKGROUND: Often the clinician is faced with a diagnostic and therapeutic dilemma in patients with concomitant traumatic brain injury (TBI) and hemorrhagic shock (HS), as rapid deterioration from either can be fatal. Knowledge about outcomes after concomitant TBI and HS may help prioritize the emergent management of these patients. We hypothesized that patients with concomitant TBI and HS (TBI + HS) had worse outcomes and required more intensive care compared with patients with only one of these injuries...
October 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28930957/clot-dynamics-and-mortality-the-ma-r-ratio
#5
Stephanie A Savage, Ben L Zarzaur, Timothy H Pohlman, Brian L Brewer, Louis J Magnotti, Martin A Croce, Garrett H Lim, Ali C Martin
INTRODUCTION: The coagulopathy of trauma, illustrated by a short R-time, is common and well understood. The physiology behind this may be early thrombin burst with rapid clot formation. Rapid consumption of fibrinogen, however, may result in weak clot and substrate depletion, resulting in low MA. While these characteristics are interesting, utilizing thromboelastography (TEG) to identify those at risk of subsequent bleeding diathesis, especially in those who do not demonstrate early signs of physiologic derangement, is challenging...
October 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28930955/comparison-of-compensatory-reserve-and-arterial-lactate-as-markers-of-shock-and-resuscitation
#6
Michael Craig Johnson, Abdul Alarhayem, Victor Convertino, Robert Carter, Kevin Chung, Ronald Stewart, John Myers, Daniel Dent, Lilian Liao, Ramon Cestero, Susannah Nicholson, Mark Muir, Martin Schwaca, David Wampler, Mark DeRosa, Brian J Eastridge
BACKGROUND: During traumatic hemorrhage, the ability to identify shock and intervene before decompensation is paramount to survival. Lactate is extremely sensitive to shock, and its clearance has been demonstrated a useful gauge of shock and resuscitation status. Though lactate can be measured in the field, logistical constraints render it impractical in certain environments. The compensatory reserve represents a new clinical measurement reflecting the remaining capacity to compensate for hypoperfusion...
October 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28930950/increased-mortality-in-trauma-patients-who-develop-postintubation-hypotension
#7
Robert S Green, Michael B Butler, Mete Erdogan
BACKGROUND: Postintubation hypotension (PIH) is common and associated with poor outcomes in critically ill patient populations requiring emergency endotracheal intubation (ETI). The importance of PIH in the trauma population remains unclear. The objective of this study was to determine the prevalence of PIH in trauma patients and assess the association of PIH with patient outcomes. METHODS: Retrospective case series of adult (≥16 years) patients who were intubated on arrival at a tertiary trauma center in Halifax, Nova Scotia, Canada, between 2000 and 2015...
October 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28930941/thoracic-irrigation-prevents-retained-hemothorax-a-prospective-propensity-scored-analysis
#8
Nathan W Kugler, Thomas W Carver, David Milia, Jasmeet S Paul
BACKGROUND: Thoracic trauma resulting in hemothorax (HTx) is typically managed with thoracostomy tube (TT) placement; however, up to 20% of patients develop retained HTx which may necessitate further intervention for definitive management. While optimal management of retained HTx has been extensively researched, little is known about prevention of this complication. We hypothesized thoracic irrigation at the time of TT placement would significantly decrease the rate of retained HTx necessitating secondary intervention...
September 20, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28930927/oral-behaviors-and-parafunctions-comparison-of-temporomandibular-dysfunction-patients-and-controls
#9
Marijus Leketas, Viktoras Šaferis, Ričardas Kubilius, Gabriele Cervino, Ennio Bramanti, Marco Cicciù
The aim of this study is to evaluate the frequency of oral behaviors in patients with temporomandibular disorders (TMD) and a control group without TMD.In this baseline case-control study, 260 controls and 260 subjects with TMD completed the oral behaviors checklist defined as a "self-report scale for identifying and quantifying the frequency of jaw overuse behavior" and underwent clinical examinations using the DC/TMJ international examination form (version May 12, 2013). Relationships of oral parafunctions' frequencies between groups were examined...
September 19, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28930855/distal-adding-on-phenomenon-in-adolescent-idiopathic-scoliosis-patients-with-thoracolumbar-vertebra-fusion-a-case-control-study
#10
Wei Xu, Chao Chen, Yifan Li, Changwei Yang, Ming Li, Zhikun Li, Xiaodong Zhu
The adding-on phenomenon is a common complication in adolescent idiopathic scoliosis (AIS) patients after correction surgery. However, the risk factors of previous studies and the optimal treatment strategies remain controversial. The aim of this study was to identify new risk factors for the adding-on phenomenon after posterior correction surgery in AIS patients and compare different treatment strategies to guide the selection of the lowest instrumented vertebra (LIV).All types of Lenke AIS patients who received correction surgery at our center from January 2009 to July 2014 were analyzed...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28930823/nonalcoholic-fatty-liver-was-associated-with-asymptomatic-gallstones-in-a-chinese-population
#11
Qiao-Hua Qiao, Wen-Hua Zhu, Yun-Xian Yu, Fei-Fei Huang, Li-Ying Chen
The aim of this study was to determine the association between nonalcoholic fatty liver disease (NAFLD) and asymptomatic gallstones in a Chinese population.The study had a cross-sectional design and enrolled 7583 subjects who visited the physical check-up center at Sir Run Run Shaw Hospital between 2009 and 2011. Colorimetric methods were used to measure the levels of cholesterol, high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C), whereas fasting plasma glucose (FPG) level was measured using a dextrose-oxidizing enzyme method...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28930818/factors-affecting-breastfeeding-adherence-among-chinese-mothers-a-multicenter-study
#12
Pan Huang, Jianhua Ren, Yi Liu, Biru Luo, Xiufang Zhao
Breastfeeding is beneficial for both infant and mother, but discontinuation of breastfeeding is very common.To investigate maternal breastfeeding intention and the rate of breastfeeding based on the theory of reasoned action, and analyze the predominant factors associated with breastfeeding and breastfeeding problems.This observational study was conducted in 3 hospitals. Three researchers recruited women at 3 time points in the hospitals: initial documentation of pregnancy at the outpatient department, prenatal admission, and postpartum discharge...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28930781/is-article-methodological-quality-associated-with-conflicts-of-interest-an-analysis-of-the-plastic-surgery-literature
#13
Brian H Cho, Joseph Lopez, Jessica Means, Sandra Lopez, Jacqueline Milton, Anthony P Tufaro, James W May, Amir H Dorafshar
PURPOSE: Conflicts of interest (COI) are an emerging area of discussion within the field of plastic surgery. Recently, several reports have found that research studies that disclose COI are associated with publication of positive outcomes. We hypothesize that this association is driven by higher-quality studies receiving industry funding. This study aimed to investigate the association between industry support and study methodological quality. METHODS: We reviewed all entries in Plastic and Reconstructive Surgery, Annals of Plastic Surgery, and Journal of Plastic, Reconstructive, and Aesthetic Surgery within a 1-year period encompassing 2013...
September 19, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28930761/factors-associated-with-medical-school-graduates-intention-to-work-with-underserved-populations-policy-implications-for-advancing-workforce-diversity
#14
Andrea N Garcia, Tony Kuo, Lisa Arangua, Eliseo J Pérez-Stable
PURPOSE: Given projected U.S. physician shortages across all specialties that will likely impact underserved areas disproportionately, the authors sought to explore factors most correlated with medical school graduates' intention to work with underserved populations (IWUP). METHOD: Data from the 2010-2012 Association of American Medical Colleges Medical School Graduation Questionnaire (n = 40,846) were analyzed. Variables (demographics, career preference, debt burden, intention to enter loan forgiveness programs) were examined using chi-square tests and logistic regression models...
September 14, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28930746/early-assessment-of-the-risk-factors-for-diabetic-retinopathy-can-reduce-the-risk-of-peripheral-arterial-and-cardiovascular-diseases-in-type-2-diabetes
#15
Juan Tang, Tao Li, Pinhong Li, Yuefei Ma, Momo Liu, Qiaoyun Shan, Fengqi Guo, Ting Zhou, Qianping Wei
BACKGROUNDS: There is still a lack of consensus about how to assess the risk of peripheral arterial disease (PAD) and cardiovascular disease (CVD) in patients with diabetic retinopathy (DR). AIMS: We investigated the risk factors for DR and their association with PAD and CVD in patients with type 2 diabetes (T2D). METHODS: A total of 1,421 patients diagnosed with T2D participated in this study. DR stages were classified as non-DR, nonproliferative DR (NPDR), or proliferative DR (PDR)...
September 21, 2017: Ophthalmic Research
https://www.readbyqxmd.com/read/28930698/2d-and-3d-ct-radiomics-features-prognostic-performance-comparison-in-non-small-cell-lung-cancer
#16
Chen Shen, Zhenyu Liu, Min Guan, Jiangdian Song, Yucheng Lian, Shuo Wang, Zhenchao Tang, Di Dong, Lingfei Kong, Meiyun Wang, Dapeng Shi, Jie Tian
OBJECTIVE: To compare 2D and 3D radiomics features prognostic performance differences in CT images of non-small cell lung cancer (NSCLC). METHOD: We enrolled 588 NSCLC patients from three independent cohorts. Two sets of 463 patients from two different institutes were used as the training cohort. The remaining cohort with 125 patients was set as the validation cohort. A total of 1014 radiomics features (507 2D features and 507 3D features correspondingly) were assessed...
September 17, 2017: Translational Oncology
https://www.readbyqxmd.com/read/28930629/large-scale-replication-study-identified-multiple-independent-snps-in-ret-synergistically-associated-with-hirschsprung-disease-in-southern-chinese-population
#17
Yan Zhang, Qiuming He, Ruizhong Zhang, Hong Zhang, Wei Zhong, Huimin Xia
Hischsprung disease (HSCR) is an intestinal disorder with strong genetic components. RET was considered as the strongest contributor. Multiple single nucleotide polymorphisms (SNP) were demonstrated as associated with HSCR in different populations. However, whether the associations of reported SNPs derived from one causal variants or congregations of multiple variants were still not clear. In this study, we successfully genotyped 16 SNPs in RET with a largest case-control study to date, totaling 1470 HSCR and 1473 control subjects in South Chinese population...
September 20, 2017: Aging
https://www.readbyqxmd.com/read/28930624/the-relationship-between-ambivalent-and-indifferent-pregnancy-desires-and-contraceptive-use-among-malawian-women
#18
Sarah Huber, Allahna Esber, Sarah Garver, Venson Banda, Alison Norris
CONTEXT: Pregnancy ambivalence and pregnancy indifference are thought to be associated with nonuse of contraceptives, but their conceptualization and measurement vary, and their relationship to contraceptive use in developing countries is poorly understood. METHODS: Data from the Umoyo wa Thanzi research program in rural Lilongwe, Malawi, were used to classify the pregnancy desires of 592 women aged 15-39 as antinatal, pronatal, ambivalent or indifferent, according to both the women's desire to conceive and their desire to avoid pregnancy...
July 5, 2017: International Perspectives on Sexual and Reproductive Health
https://www.readbyqxmd.com/read/28930623/multipartner-fertility-in-nicaragua-complex-family-formation-in-a-low-income-setting
#19
Kammi K Schmeer, Jake Hays
CONTEXT: Multipartner fertility (having children with more than one partner) is an important topic in demographic research, but little is known about its incidence and correlates in low-income settings, where rates may be high because of poverty, union instability and early childbearing. METHODS: Data from the 2011-2012 Encuesta Nicaragüense de Demografía y Salud were used to calculate the prevalence of multipartner fertility among 8,320 mothers and 2,141 fathers with two or more children...
March 3, 2017: International Perspectives on Sexual and Reproductive Health
https://www.readbyqxmd.com/read/28930495/a-multicenter-real-life-study-on-the-effect-of-flash-glucose-monitoring-on-glycemic-control-in-patients-with-type-1-and-type-2-diabetes
#20
Ranjit Mohan Anjana, Jothydev Kesavadev, Deshpande Neeta, Mangesh Tiwaskar, Rajendra Pradeepa, Saravanan Jebarani, Suresh Thangamani, Nadiminty Ganapathi Sastry, Srivastava Brijendra Kumar, Muthu Ramu, Pokal Prasanna Kumar Gupta, Jayaprakash Vignesh, Sundramoorthy Chandru, Sengottuvel Kayalvizhi, Padoor Sethuraman Jagdish, Subash Chandra Bose Uthra, Munawar Lovelena, Sah Jyoti, Sengodan Suguna Priya, Alagarsamy Kannan, Viswanathan Mohan, Ranjit Unnikrishnan
AIM: To assess the efficacy of ambulatory glucose profiling (AGP) generated by FreeStyle LibrePro(™) flash glucose monitoring (FCGM) on glycemic control in patients with uncontrolled type 1 diabetes (T1D) and type 2 diabetes (T2D). METHODS: Clinical and biochemical data were obtained from 5072 patients with diabetes who had an A1c ≥7% (2536 who had been initiated on FCGM-based AGP between March 2015 and October 2016 [cases] and 2536 age-, gender-, A1c-, site- and time-matched controls who were not initiated on AGP) across seven diabetes clinics in India...
September 2017: Diabetes Technology & Therapeutics
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