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https://www.readbyqxmd.com/read/28215036/serum-levels-of-homocysteine-at-admission-are-associated-with-post-stroke-depression-in-acute-ischemic-stroke
#1
Yan Li, Li-Li Cao, Lin Liu, Qin-De Qi
The primary purpose of this study was to assess the serum levels of homocysteine (HCY) at admission to the presence of post-stroke depression (PSD). From September 2014 to December 2015, first-ever acute ischemic stroke patients within the first 24 h after stroke onset were consecutively recruited and followed-up for 3 months. Based on the symptoms, diagnoses of depression were made in accordance with DSM-IV criteria for depression. By the time of 3 month after stroke, 238 had finished the follow-up and included in our study...
February 18, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28214954/association-of-toll-like-receptor-4-single-nucleotide-polymorphisms-asp299gly-and-thr399ile-with-the-risk-of-primary-open-angle-glaucoma
#2
Jose Navarro-Partida, Abril Bernardette Martinez-Rizo, Pedro Ramirez-Barrera, Jesus Bernardino Velazquez-Fernandez, Veronica A Mondragon-Jaimes, Arturo Santos-Garcia, Veronica Benites-Godinez
PURPOSE: Toll-like receptor 4 (TLR4) is a transmembrane receptor that mediates immune responses to exogenous and endogenous ligands. Previously, non-coding single nucleotide polymorphisms (SNPs) in the TLR4 gene were related to primary open angle glaucoma (POAG). This study was undertaken to investigate whether coding TLR4 Asp299Gly (rs4986790 A/G) and Thr399Ile (rs4986791 C/T) are associated with POAG in a Mexican population. METHODS: One hundred and eighty-seven unrelated Mexican patients with POAG (94 men and 95 women; mean age 66...
February 18, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28214846/circulating-mir-30d-predicts-survival-in-patients-with-acute-heart-failure
#3
Junjie Xiao, Rongrong Gao, Yihua Bei, Qiulian Zhou, Yanli Zhou, Haifeng Zhang, Mengchao Jin, Siqi Wei, Kai Wang, Xuejuan Xu, Wenming Yao, Dongjie Xu, Fang Zhou, Jingfa Jiang, Xinli Li, Saumya Das
BACKGROUND/AIMS: Identification of novel biomarkers to identify acute heart failure (AHF) patients at high risk of mortality is an area of unmet clinical need. Recently, we reported that the baseline level of circulating miR-30d was associated with left ventricular remodeling in response to cardiac resynchronization therapy in advanced chronic heart failure patients. However, the role of circulating miR-30d as a prognostic marker of survival in patients with AHF has not been explored...
February 16, 2017: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/28214795/pre-implantation-balloon-aortic-valvuloplasty-and-clinical-outcomes-following-transcatheter-aortic-valve-implantation-a-propensity-score-analysis-of-the-uk-registry
#4
Glen P Martin, Matthew Sperrin, Rodrigo Bagur, Mark A de Belder, Iain Buchan, Mark Gunning, Peter F Ludman, Mamas A Mamas
BACKGROUND: Aortic valve predilation with balloon aortic valvuloplasty (BAV) is recommended before transcatheter aortic valve implantation (TAVI), despite limited data around the requirement of this preprocedural step and the potential risks of embolization. This study aimed to investigate the trends in practice and associations of BAV on short-term outcomes in the UK TAVI registry. METHODS AND RESULTS: Eleven clinical endpoints were investigated, including 30-day mortality, myocardial infarction, aortic regurgitation, valve dysfunction, and composite early safety...
February 18, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28214781/cannabis-use-and-the-course-and-outcome-of-major-depressive-disorder-a-population-based-longitudinal-study
#5
Daniel Feingold, Jürgen Rehm, Shaul Lev-Ran
Cannabis use has been reported to affect the course of various psychiatric disorders, however its effect on the course of major depressive disorder (MDD) is not yet clear. We used data from Wave 1 and Wave 2 of the National Epidemiologic survey on Alcohol and Related Conditions (NESARC). Individuals with baseline MDD (N=2,348) were included in the study. Cannabis users without a Cannabis Use Disorder (CUDs) and individuals with a CUD were compared to nonusers using linear and logistic regression analyses controlling for sociodemographics, psychiatric disorders and substance use disorders at baseline...
February 12, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28214760/genotyping-analysis-of-protein-s-tokushima-k196e-and-the-involvement-of-protein-s-antigen-and-activity-in-patients-with-recurrent-pregnancy-loss
#6
Yasushi Matsukawa, Eriko Asano, Tomohide Tsuda, Hiroyuki Kuma, Tamao Kitaori, Kinue Katano, Yasuhiko Ozaki, Mayumi Sugiura-Ogasawara
OBJECTIVE: Preston et al. indicated that Protein S (PS) deficiency was associated with stillbirths but not miscarriages. The PS-Tokushima missense variant was reported to serve as a genetic risk factor for deep vein thrombosis in the Japanese population. A previous cross-sectional study showed no increase in the prevalence of PS-Tokushima in patients with recurrent early pregnancy loss or in patients with intra uterine fetal death and/or fetal growth restriction. There has been limited number of prospective studies examining the pregnancy outcome in patients with both a PS deficiency and recurrent pregnancy loss (RPL)...
February 8, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28214759/the-role-of-hcg-increment-in-the-48h-prior-to-methotrexate-treatment-as-a-predictor-for-treatment-success
#7
Aviad Cohen, Benny Almog, Yoni Cohen, Guy Bibi, Eli Rimon, Ishai Levin
OBJECTIVE: To evaluate the role HCG change in the 48h prior to methotrexate treatment as a predictor for treatment success. STUDY DESIGN: Medical records of all women who were diagnosed with ectopic pregnancy between January 2001 and June 2013 were reviewed. Four hundred and nine patients received methotrexate due to ectopic pregnancy. The "single dose" methotrexate protocol with 50mg/m(2) was administered to patients with progressing ectopic pregnancy. HCG levels in days 1, 4 and 7 were used to evaluate methotrexate treatment success...
February 9, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28214742/what-s-the-agreement-between-self-reported-and-biochemical-verification-of-drug-use-a-look-at-permanent-supportive-housing-residents
#8
Alexis Rendon, Melvin Livingston, Sumihiro Suzuki, Whitney Hill, Scott Walters
Self-reported substance use is commonly used as an outcome measure in treatment research. We evaluated the validity of self-reported drug use in a sample of 334 adults with mental health problems who were residing in supportive housing programs. The primary analysis was the calculation of the positive predictive values (PPVs) of self-report compared to an oral fluid test taken at the same time. A sensitivity analysis compared the positive predictive values of two self-reported drug use histories: biological testing window (ranging between the past 96h to 30days depending on drug type) or the full past 90-day comparison window (maximum length recorded during interview)...
February 10, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28214740/youth-use-of-electronic-vapor-products-and-blunts-for-administering-cannabis
#9
Matthew E Eggers, Youn O Lee, Kyle Jackson, Jenny L Wiley, Lauren Porter, James M Nonnemaker
BACKGROUND: The positive association between youth use of cannabis and tobacco is well-established, and reports show that some youth are using electronic vapor products (EVPs) to administer cannabis. This study examines the prevalence and correlates of youth consumption of cannabis via EVP and how this compares with co-use of cannabis with cigars (blunts) among a large statewide sample of youth. METHODS: We used data from the Florida Youth Tobacco Survey (FYTS), a school-based, pencil-and-paper questionnaire given to Florida middle and high school students (N=12,320)...
February 10, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28214669/correlates-of-overweight-and-obesity-in-5529-adolescents-with-type-1-diabetes-the-t1d-exchange-clinic-registry
#10
Karl E Minges, Robin Whittemore, Stuart A Weinzimer, Melinda L Irwin, Nancy S Redeker, Margaret Grey
AIMS: To describe the prevalence of overweight and obesity in adolescents with type 1 diabetes (T1D) and to examine the associations among socio-demographic, clinical, and self-management factors by weight status. METHODS: We analyzed baseline data obtained from 5529 adolescents with T1D (mean age=15.4±1.4years, 51.8% male, 77.9% white, mean HbA1c=8.7±1.8%; 72mmol/mol) from the T1D Exchange Clinic Registry. We examined correlates of weight status using multinomial logistic regression analyses...
February 4, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28214658/an-association-study-of-established-breast-cancer-reproductive-and-lifestyle-risk-factors-with-tumour-subtype-defined-by-the-prognostic-70-gene-expression-signature-mammaprint-%C3%A2
#11
M Makama, C A Drukker, E J Th Rutgers, L Slaets, F Cardoso, M A Rookus, K Tryfonidis, L J Van't Veer, M K Schmidt
BACKGROUND: Reproductive and lifestyle factors influence both breast cancer risk and prognosis; this might be through breast cancer subtype. Subtypes defined by immunohistochemical hormone receptor markers and gene expression signatures are used to predict prognosis of breast cancer patients based on their tumour biology. We investigated the association between established breast cancer risk factors and the 70-gene prognostication signature in breast cancer patients. PATIENTS AND METHODS: Standardised questionnaires were used to obtain information on established risk factors of breast cancer from the Dutch patients of the MINDACT trial...
February 16, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28214638/pre-residency-publication-number-does-not-predict-academic-career-placement-in-neurosurgery
#12
Marcus Daniels, Tomas Garzon-Muvdi, Russell Maxwell, Rafael J Tamargo, Judy Huang, Tim Witham, Chetan Bettegowda, Kaisorn L Chaichana
OBJECTIVE: It is unclear if pre-residency and/or residency research work impacts academic neurosurgery placement post-residency. The goal of this study is to evaluate the impact that pre-residency and residency research publication has on attaining academic faculty positions. METHODS: Alumni information was collected from 65 of the 108 (60%) neurosurgery residency websites. Graduates from these programs between 2005-2015 (N=949) were analyzed to determine factors associated with an academic career...
February 15, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28214616/exploring-factors-influencing-low-back-pain-in-people-with-non-dysvascular-lower-limb-amputation-a-national-survey
#13
Hemakumar Devan, Paul Hendrick, Leigh Hale, Allan Carman, Michael P Dillon, Daniel Cury Ribeiro
BACKGROUND: Chronic low back pain (LBP) is a common musculoskeletal impairment in people with lower limb amputation. Given the multifactorial nature of LBP, exploring the factors influencing the presence and intensity of LBP is warranted. OBJECTIVE: To investigate which physical, personal, and amputee-specific factors predicted presence and intensity of low back pain (LBP) in persons with non-dysvascular transfemoral (TFA) and transtibial amputation (TTA). DESIGN: A retrospective cross-sectional survey SETTING: A national random sample of people with non-dysvascular TFA and TTA...
February 15, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28214597/classification-criteria-versus-physician-s-opinion-for-considering-a-patient-with-inflammatory-back-pain-as-suffering-from-spondyloarthritis
#14
Pierre Gazeau, Divi Cornec, Marie Agnes Timsit, Maxime Dougados, Alain Saraux
OBJECTIVE: To assess agreement among methods for classifying patients with inflammatory back pain [IBP] after a 2-year follow up. METHODS: Patients with IBP in the French nationwide, longitudinal, prospective cohort DESIR were classified after 2 years based on imaging findings, rheumatologist's confidence in a diagnosis of spondyloarthritis, three classification criteria sets [axial Assessment of Spondyloarthritis international Society (ASAS), European Spondylarthropathy Study Group (ESSG), and Amor] and treatment [TNFα antagonists]...
February 15, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28214574/minimally-invasive-versus-open-approach-for-cystectomy-trends-in-the-utilization-and-demographic-or-clinical-predictors-using-the-national-cancer-database-ncdb
#15
Andrew G Bachman, Alexander A Parker, Marshall D Shaw, Brian W Cross, Kelly L Stratton, Michael S Cookson, Sanjay G Patel
OBJECTIVES: To examine temporal national trends of operative approach for cystectomy and identify demographic or clinical predictive factors that influence choice of approach. METHODS: We performed a retrospective cohort study of patients who underwent cystectomy for bladder cancer between 2010 and 2013 using the National Cancer Database (NCDB). Approach was stratified by open vs. minimally invasive (robotic or laparoscopic). Univariate Pearson chi-square and multivariate logistic regression analysis was used to assess relationships between demographic and hospital factors and the receipt of minimally invasive or open surgical approach...
February 15, 2017: Urology
https://www.readbyqxmd.com/read/28214487/radiofrequency-ablation-with-concomitant-stab-phlebectomy-increases-risk-of-endovenous-heat-induced-thrombosis
#16
Caitlin W Hicks, Sandra R DiBrito, J Trent Magruder, M Libby Weaver, Cathy Barenski, Jennifer A Heller
OBJECTIVE: Endovenous heat-induced thrombosis (EHIT) is a well-documented phenomenon that follows endovenous ablation, but the treatment, surveillance, and risk factors for EHIT have yet to be comprehensively elucidated. We sought to identify characteristics that may put patients at higher risk for development of EHIT after radiofrequency ablation (RFA) for the treatment of symptomatic superficial venous insufficiency. METHODS: A retrospective review was performed of all consecutive patients undergoing treatment with RFA to the great saphenous vein by a single surgeon from July 2013 through October 2015...
March 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28214435/evaluation-of-fertility-after-operative-hysteroscopy-to-remove-retained-products-of-conception
#17
Louise Sonnier, Antoine Torre, Pauline Broux, Arnaud Fauconnier, Cyrille Huchon
: Evaluation of fertility after operative hysteroscopy to remove retained products of conception. OBJECTIVE: To study fertility after operative hysteroscopy for the management of prolonged trophoblastic retention, and the complications of this procedure. STUDY DESIGN: Retrospective cohort in a university hospital. RESULTS: 115 patients underwent operative hysteroscopy for the treatment of prolonged post-partum and post-abortum retention between January 2008 and December 2011...
February 6, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28214386/management-and-prognosis-of-hcc-in-the-elderly-results-of-an-in-field-multicenter-cohort-study
#18
Mauro Borzio, Elena Dionigi, Alessandro Vitale, Angelo Rossini, Massimo Marignani, Fabio Fornari, Susanna Vicari, Ilario De Sio, Fabio Farinati, Emanuela Bertolini, Filippo Oliveri, Gioacchino Leandro, Giampiero Francica, Mario Mitra, Barbara Omazzi, Sergio Boccia, Andrea Salmi, Anna Toldi, Rodolfo Sacco
AIMS: This multicentre cohort study evaluated the role of aging on clinical characteristics, treatment allocation, and outcome of new HCCs, in clinical practice. MATERIAL AND METHODS: From September 2008, 541 patients aged > 70 years old (elderly group), and 527 ≤ 70 years old (non elderly group) with newly diagnosed HCC were consecutively enrolled in 30 Italian centres. Differences in clinical characteristics and treatment allocation between groups were described by a multivariable logistic regression model measuring the inverse probability weight to meet the elderly group...
February 18, 2017: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/28214384/placental-pathology-in-hiv-infection-at-term-a-comparison-with-hiv-uninfected-women
#19
Emma Kalk, Pawel Schubert, Julie A Bettinger, Mark F Cotton, Monika Esser, Amy Slogrove, Colleen A Wright
OBJECTIVES: To describe and correlate placental characteristics from pregnancies in HIV-infected and HIV-negative women with maternal and infant clinical and immunological data. METHODS: Prospective descriptive study of placentas from term, uncomplicated vaginal births in a cohort of HIV-infected (n=120) and HIV-negative (n=103) women in Cape Town, South Africa. Microscopic and macroscopic features were used to determine pathological cluster diagnoses. The majority of HIV-infected women received some form of drug treatment for the prevention of vertical transmission of HIV...
February 18, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28214362/is-there-an-association-between-verbal-school-bullying-and-possible-sleep-bruxism-in-adolescents
#20
Junia Maria Serra-Negra, Isabela Almeida Pordeus, Patricia Corrêa-Faria, Livia Bonfim Fulgêncio, Saul Martins Paiva, Daniele Manfredini
The aim of this study was to determine the association between verbal school bullying and possible sleep bruxism (SB) in adolescents. A case-control study was carried out at the population level by recruiting 13- to 15-year old participants among the attendants of schools of Itabira, Brazil. The case group was composed of 103 adolescents with possible SB (i.e., self- or parental-reported), while the control group included 206 adolescents without possible SB. All participants answered a questionnaire on the occurrence of their involvement in verbal school bullying episodes, based on the National School of Health Research (PeNSE) as well as an evaluation of their economic class according to the criteria of the Brazilian Association of Research Companies...
February 18, 2017: Journal of Oral Rehabilitation
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