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https://www.readbyqxmd.com/read/29235263/detection-and-genetic-characterization-of-diverse-bartonella-genotypes-in-the-small-mammals-of-singapore
#1
E S Neves, I H Mendenhall, S A Borthwick, Y C F Su, G J D Smith
Bartonella species are arthropod-borne bacterial pathogens that infect numerous mammalian species. Small mammals play an important role as natural reservoirs of many Bartonella species, maintaining the greatest diversity of Bartonella described to date. Although Bartonella research has been conducted in Southeast Asia, no studies have been undertaken on small mammals in Singapore. Here, we report the detection and description of Bartonella in small mammals in Singapore during the period of November 2011 to May 2014...
December 12, 2017: Zoonoses and Public Health
https://www.readbyqxmd.com/read/29233492/-haemophagocytic-syndrome-secondary-to-endocarditis-due-to-bartonella-henselae
#2
Esmeralda Núñez Cuadros, Ana Cabrera Del Moral, Jose Manuel Jiménez Hinojosa, Isabel Leiva Gea, Lourdes Conejo Muñoz
No abstract text is available yet for this article.
December 7, 2017: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/29217417/cat-fleas-ctenocephalides-felis-carrying-rickettsia-felis-and-bartonella-species-in-hong-kong
#3
Jan Šlapeta, Andrea Lawrence, Michael P Reichel
Fleas are commonly recorded on stray as well as domestic dogs and cats in Hong Kong. Fleas can be a major cause of pruritus in dogs and cats and also vectors of potentially zoonotic bacteria in the genera Rickettsia and Bartonella. Morphological examination of 174 fleas from dogs and cats living in Hong Kong revealed only cat fleas (Ctenocephalides felis). Cytochrome c oxidase subunit 1 gene (cox1) genotyping of 20 randomly selected specimens, revealed three cox1 haplotypes (HK-h1 to HK-h3). The most common haplotype was HK-h1 with 17 specimens (17/20, 85%)...
December 4, 2017: Parasitology International
https://www.readbyqxmd.com/read/29209691/a-case-of-infective-endocarditis-due-to-salmonella-enterica-phagetype-35-first-report
#4
P Laganà, S Delia, G Dattilo, C Mondello, E Ventura Spagnolo
Infective Endocarditis (IE) has high morbidity and mortality. To date, in addition to classic Gram-positive pathogens were isolated exigent Gram negative bacteria responsible of endocarditis as A. baumannii, A. lwoffii, C. burnetii, Bartonella, Chlamydia and Legionella. We report our experience about the isolation of Salmonella enterica phagetype 35 (PT35) from blood heart cavity of a 74-year-old woman after having consumed a portion of baked pasta bought in a rotisserie. Cardiovascular infections due to Salmonella enterica are infrequently reported, so their clinical features, prognosis, and optimal treatment are not completely known...
November 2017: La Clinica Terapeutica
https://www.readbyqxmd.com/read/29203105/bartonella-infection-in-asymptomatic-horses-and-donkeys-from-tuscany-central-italy
#5
Edoardo Magni, Fabrizio Bertelloni, Micaela Sgorbini, Valentina V Ebani
OBJECTIVE: To investigate the occurrence of Bartonella sp. infection in asymptomatic horses and donkeys living in Tuscany, Central Italy. METHODS: Blood samples were collected from 77 horses and 15 donkeys and tested by indirect immunofluorescent test to detect antibodies against Bartonella sp. and by PCR to detect the pathogen. RESULTS: Fifty-four (58.69%; 95% CI: 47.95%-68.87%) animals, 9 donkeys and 45 horses, were seropositive with antibody titers ranging from 1:64 to 1:512...
November 2017: Asian Pacific Journal of Tropical Medicine
https://www.readbyqxmd.com/read/29197186/bartonella-seroepidemiology-in-dogs-from-north-america-2008-2014
#6
E Lashnits, M Correa, B C Hegarty, A Birkenheuer, E B Breitschwerdt
BACKGROUND: Improved understanding of Bartonella species seroepidemiology in dogs may aid clinical decision making and enhance current understanding of naturally occurring arthropod vector transmission of this pathogen. OBJECTIVES: To identify demographic groups in which Bartonella exposure may be more likely, describe spatiotemporal variations in Bartonella seroreactivity, and examine co-exposures to other canine vector-borne diseases (CVBD). ANIMALS: A total of 15,451 serology specimens from dogs in North America were submitted to the North Carolina State University, College of Veterinary Medicine Vector Borne Disease Diagnostic Laboratory between January 1, 2008, and December 31, 2014...
December 2, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/29191209/co-infection-with-bartonella-bacilliformis-and-mycobacterium-spp-in-a-coastal-region-of-peru
#7
Wilmer Silva-Caso, Fernando Mazulis, Claudia Weilg, Miguel Angel Aguilar-Luis, Isabel Sandoval, German Correa-Nuñez, Dongmei Li, Xiuping Song, Qiyong Liu, Juana Del Valle-Mendoza
OBJECTIVE: This study investigated an outbreak of Bartonellosis in a coastal region in Peru. RESULTS: A total of 70 (n = 70) samples with clinical criteria for the acute phase of Bartonellosis and a positive peripheral blood smear were included. 22.85% (n = 16) cases of the samples were positive for Bartonella bacilliformis by PCR and automatic sequencing. Of those positive samples, 62.5% (n = 10) cases were positive only for B. bacilliformis and 37.5% (n = 6) cases were positive to both Mycobacterium spp...
December 1, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/29187394/carrion-s-disease-the-sound-of-silence
#8
REVIEW
Cláudia Gomes, Joaquim Ruiz
Carrion's disease (CD) is a neglected biphasic vector-borne illness related to Bartonella bacilliformis. It is found in the Andean valleys and is transmitted mainly by members of the Lutzomyia genus but also by blood transfusions and from mother to child. The acute phase, Oroya fever, presents severe anemia and fever. The lethality is high in the absence of adequate treatment, despite the organism being susceptible to most antibiotics. Partial immunity is developed after infection by B. bacilliformis, resulting in high numbers of asymptomatic carriers...
January 2018: Clinical Microbiology Reviews
https://www.readbyqxmd.com/read/29176527/cat-scratch-disease-imitating-a-toxocara-granuloma-of-the-optic-disk
#9
Fouad E Sayyad, Ahmaida Zeglam, Swati Agarwal-Sinha
PURPOSE: The study reports an unusual presentation of a young female patient presenting with a granulomatous posterior pole mass and profound vision loss secondary to infection with Bartonella henselae. METHODS: A single case report in a child. RESULTS: An 8-year-old female presented with a recent history of flu-like illness associated with profound vision loss, panuveitis and leukocoria in the left eye. She was found to have a posterior granulomatous mass associated with an exudative retinal detachment presumed as a toxocara granuloma...
November 22, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/29165524/-bartonella-henselae-infection-the-importance-of-images-for-diagnosis-and-follow-up
#10
M Fernanda Tapia, Reinaldo Rosas, Giancarlo Schiappacasse, Luis Thompson
Bartonella henselae infection is a frequent zoonosis from the domestic cat. It is presented with regional lymphadenitis in the majority of cases. Searching and characterization of lymph nodes by diagnostic imaging can be useful in the differential diagnosis approach, with a clear advantage, because it is a noninvasive method. Currently, new diagnostic imaging techniques improves the quality of screening and characterization of adenopathies, such is the case of PET/CT, which allows a better evaluation of hypermetabolic lymph nodes, without considering the individual growth of each lymph node...
August 2017: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://www.readbyqxmd.com/read/29165519/-central-nervous-system-infection-by-bartonella-henselae-associated-with-a-choroid-plexus-papilloma
#11
Natalia Barnafi, Natalia Conca, Cecilia von Borries, Isabel Fuentes, Francisca Montoya, Elisa Alcalde
Bartonella henselae infection is a prevalent illness in Chile. It presents generally as a cat scratch disease or as a prolonged fever syndrome. There are atypical manifestations, which include central nervous system, bone, cardiac and hepato-esplenic compromised. We present an adolescent case with a history of fever, vomiting and ataxia, whose diagnosis was a central nervous system infection by Bartonella henselae associated with a choroid plexus papilloma. This case corresponds to an unusual presentation, with a challenging diagnosis...
August 2017: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://www.readbyqxmd.com/read/29164472/rodent-borne-bartonella-infection-varies-according-to-host-species-within-and-among-cities
#12
Anna C Peterson, Bruno M Ghersi, Fernando Alda, Cadhla Firth, Matthew J Frye, Ying Bai, Lynn M Osikowicz, Claudia Riegel, W Ian Lipkin, Michael Y Kosoy, Michael J Blum
It is becoming increasingly likely that rodents will drive future disease epidemics with the continued expansion of cities worldwide. Though transmission risk is a growing concern, relatively little is known about pathogens carried by urban rats. Here, we assess whether the diversity and prevalence of Bartonella bacteria differ according to the (co)occurrence of rat hosts across New Orleans, LA (NO), where both Norway (Rattus norvegicus) and roof rats (Rattus rattus) are found, relative to New York City (NYC) which only harbors Norway rats...
November 21, 2017: EcoHealth
https://www.readbyqxmd.com/read/29162422/chlamydiales-anaplasma-and-bartonella-persistence-and-immune-escape-of-intracellular-bacteria
#13
Aurélie Scherler, Nicolas Jacquier, Gilbert Greub
Intracellular bacteria, such as Chlamydiales, Anaplasma or Bartonella, need to persist inside their host in order to complete their developmental cycle and to infect new hosts. In order to escape from the host immune system, intracellular bacteria have developed diverse mechanisms of persistence, which can directly impact the health of their host.
November 18, 2017: Microbes and Infection
https://www.readbyqxmd.com/read/29161442/origin-and-evolution-of-the-bartonella-gene-transfer-agent
#14
Daniel Tamarit, Minna-Maria Neuvonen, Philipp Engel, Lionel Guy, Siv G E Andersson
Gene transfer agents (GTAs) are domesticated bacteriophages that have evolved into molecular machines for the transfer of bacterial DNA. Despite their widespread nature and their biological implications, the mechanisms and selective forces that drive the emergence of GTAs are still poorly understood. Two GTAs have been identified in the Alphaproteobacteria: the RcGTA, which is widely distributed in a broad range of species; and the BaGTA, which has a restricted host range that includes vector-borne intracellular bacteria of the genus Bartonella...
November 17, 2017: Molecular Biology and Evolution
https://www.readbyqxmd.com/read/29160523/infective-endocarditis-due-to-bartonella-bacilliformis-associated-with-systemic-vasculitis-a-case-report
#15
Joshua Peñafiel-Sam, Samuel Alarcón-Guevara, Sergio Chang-Cabanillas, Wilkerson Perez-Medina, Fernando Mendo-Urbina, Eloy Ordaya-Espinoza
Infective endocarditis due to Bartonella bacilliformis is rare. A 64-year-old woman, without previous heart disease, presented with 6 weeks of fever, myalgias, and arthralgias. A systolic murmur was heard on the tricuspid area upon examination, and an echocardiogram showed endocardial lesions in the right atrium. Bartonella bacilliformis was isolated in blood cultures, defining the diagnosis of infective endocarditis using Duke's criteria. Subsequently, the patient developed clinical and laboratory features compatible with antineutrophil cytoplasmic antibody-associated vasculitis...
September 2017: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/29160357/co-infection-with-arthropod-borne-pathogens-in-domestic-cats
#16
Marcos Rogério André, Kilder Dantas Filgueira, Ana Cláudia Calchi, Keyla Carstens Marques de Sousa, Luiz Ricardo Gonçalves, Vitor Brasil Medeiros, Poliana Araújo Ximenes, Ivana Cristina Nunes Gadelha Lelis, Maria Vanuza Nunes de Meireles, Rosangela Zacarias Machado
The role of several feline vector-borne pathogens (FVBP) as a cause of disease in cats has not been clearly determined. In fact, with the exception of Bartonella spp. and hemoplasmas, FVBP in cats has not been clearly determined in Brazil yet. The present study aimed at identifying, by using molecular methods, the presence of FVBP in three cats showing non-specific clinical signs and inclusions suggestive of hemoparasites in blood smears. Cytauxzoon felis, 'Candidatus Mycoplasma haemominutum', Ehrlichia sp...
November 9, 2017: Revista Brasileira de Parasitologia Veterinária, Brazilian Journal of Veterinary Parasitology
https://www.readbyqxmd.com/read/29159996/demographic-characteristics-of-teenage-boys-with-horizontal-striae-distensae-of-the-lower-back
#17
Emily Boozalis, Anna L Grossberg, Katherine B Puttgen, Candrice R Heath, Bernard A Cohen
BACKGROUND: This study examines the clinical characteristics and demographics of teenage boys with horizontal striae distensae of the lower back in an outpatient setting. METHODS: Retrospective medical chart reviews and telephone survey studies were completed on an outpatient cohort of 12 boys 11 to 17 years of age with a clinical diagnosis of transverse striae distensae of the lower back at a single-center, university-based, pediatric dermatology practice. We evaluated the clinical features of the striae, participant demographic characteristics, and past medical history...
November 21, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/29147875/evaluation-of-nfsa-like-nitroreductases-from-neisseria-meningitidis-and-bartonella-henselae-for-enzyme-prodrug-therapy-targeted-cellular-ablation-and-dinitrotoluene-bioremediation
#18
Michelle H Rich, Abigail V Sharrock, Kelsi R Hall, David F Ackerley, Joanna K MacKichan
OBJECTIVES: To characterize the activities of two candidate nitroreductases, Neisseria meningitidis NfsA (NfsA_Nm) and Bartonella henselae (PnbA_Bh), with the nitro-prodrugs, CB1954 and metronidazole, and the environmental pollutants 2,4- and 2,6-dinitrotoluene. RESULTS: NfsA_Nm and PnbA_Bh were evaluated in Escherichia coli over-expression assays and as His6-tagged proteins in vitro. With the anti-cancer prodrug CB1954, both enzymes were more effective than the canonical O2-insensitive nitroreductase E...
November 17, 2017: Biotechnology Letters
https://www.readbyqxmd.com/read/29145396/detection-of-relapsing-fever-borrelia-spp-bartonella-spp-and-anaplasmataceae-bacteria-in-argasid-ticks-in-algeria
#19
Ismail Lafri, Basma El Hamzaoui, Idir Bitam, Hamza Leulmi, Reda Lalout, Oleg Mediannikov, Mohamed Chergui, Mohamed Karakellah, Didier Raoult, Philippe Parola
BACKGROUND: Argasid ticks (soft ticks) are blood-feeding arthropods that can parasitize rodents, birds, humans, livestock and companion animals. Ticks of the Ornithodoros genus are known to be vectors of relapsing fever borreliosis in humans. In Algeria, little is known about relapsing fever borreliosis and other bacterial pathogens transmitted by argasid ticks. METHODOLOGY/PRINCIPAL FINDINGS: Between May 2013 and October 2015, we investigated the presence of soft ticks in 20 rodent burrows, 10 yellow-legged gull (Larus michahellis) nests and animal shelters in six locations in two different bioclimatic zones in Algeria...
November 16, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29141959/an-integrative-strategy-to-identify-the-entire-protein-coding-potential-of-prokaryotic-genomes-by-proteogenomics
#20
Ulrich Omasits, Adithi R Varadarajan, Michael Schmid, Sandra Goetze, Damianos Melidis, Marc Bourqui, Olga Nikolayeva, Maxime Québatte, Andrea Patrignani, Christoph Dehio, Juerg E Frey, Mark D Robinson, Bernd Wollscheid, Christian H Ahrens
Accurate annotation of all protein-coding sequences (CDSs) is an essential prerequisite to fully exploit the rapidly growing repertoire of completely sequenced prokaryotic genomes. However, large discrepancies among the number of CDSs annotated by different resources, missed functional short open reading frames (sORFs), and overprediction of spurious ORFs represent serious limitations. Our strategy toward accurate and complete genome annotation consolidates CDSs from multiple reference annotation resources, ab initio gene prediction algorithms and in silico ORFs (a modified six-frame translation considering alternative start codons) in an integrated proteogenomics database (iPtgxDB) that covers the entire protein-coding potential of a prokaryotic genome...
December 2017: Genome Research
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