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https://www.readbyqxmd.com/read/28735196/molecular-dynamics-simulation-of-sodium-dodecylsulfate-sds-bilayers
#1
Hongshu Zhang, Shiling Yuan, Jichao Sun, Jianqiang Liu, Haiping Li, Na Du, Wanguo Hou
Sodium dodecylsulfate (SDS) - a simple single tailed surfactant (STS) can form stable vesicles from its micellar solution without any additives under the mediation of solid surfaces. To further understand the mechanism of this transition on the molecular level, molecular dynamics simulations are performed to study segments of SDS bilayers (as part of vesicles) in the bulk solution systematically, at the moment that the lower leaflet of bilayers already detached from solid surfaces. The SDS membrane would rather keep their bilayers structure than return to micelles when the initial interdigitated degree (δi) between alkyl chains is more than 8...
July 15, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28735117/pubic-osteomyelitis-after-surgery-for-perforated-colonic-diverticulitis-with-fecal-peritonitis-a-case-report
#2
Daichi Kitaguchi, Tsuyoshi Enomoto, Yusuke Ohara, Tatsuya Oda, Nobuhiro Ohkohchi
INTRODUCTION: Pubic osteomyelitis is a rare type of suppurative osteomyelitis. Early diagnosis of pubic osteomyelitis is difficult, and prolonged inflammation results in progressive bone degradation, severe pelvic pain and a wide-based gait. PRESENTATION OF CASE: We report the case of an 82-year-old woman who was admitted to a previous hospital with severe abdominal pain caused by a perforated colonic diverticulum with fecal peritonitis. She underwent an emergency operation and a postoperative wound infection occurred...
July 13, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28734992/endoscopic-muscle-biopsy-emb-of-the-duodenum-and-rectum-a-pilot-survival-study-in-a-porcine-model-to-detect-myenteric-neurons
#3
E Rajan, B Al-Bawardy, C J Gostout, L M Wong Kee Song, J L Deters, M A Knipschield, C E Bernard, G Farrugia
BACKGROUND AND AIMS: Small bowel and colorectal muscle biopsies require a surgical approach. Advancing our understanding of the pathophysiology of motility disorders, such as functional bowel disorders, intestinal pseudo-obstruction and slow transit constipation, is hindered by our inability to non-invasively obtain muscularis propria (MP) for evaluation of multiple cell types, including myenteric neurons. The aims of this study were to determine (1) technical feasibility, reproducibility and safety of performing duodenal endoscopic muscle biopsy (dEMB) and rectal endoscopic muscle biopsy (rEMB) using a clip-assist technique; and (2) presence of myenteric neurons in tissue samples...
July 19, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28734985/safety-of-catheter-ablation-for-atrial-fibrillation-using-fiber-optic-based-contact-force-sensing
#4
Moussa Mansour, Dhanunjaya Lakkireddy, Douglas Packer, John D Day, Srijoy Mahapatra, Kyle Brunner, Vivek Reddy, Andrea Natale
BACKGROUND: While the body of evidence showing the benefit of contact force (CF) sensing catheters in improving AF ablation success rate is growing, real-world safety data of this technology are limited. OBJECTIVE: The aim of this study is to report the complication rate in patients undergoing ablation using one specific CF sensing catheter (TactiCath™Quartz Contact Force Ablation Catheter (Abbott, St Paul, MN)) in a large worldwide database. METHODS: - User-reported adverse event data from January 2014 - December 2015 was reviewed for the ablation catheter...
July 19, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28734659/comparative-effectiveness-study-between-negative-pressure-wound-therapy-and-conventional-wound-dressing-on-perforator-flap-at-the-chinese-tertiary-referral-teaching-hospital
#5
Regis Ernest Mendame Ehya, Yong Zhao, Xun Zheng, Wanrong Yi, Guy-Armel Bounda, Zonghuan Li, Weidong Xiao, Aixi Yu
BACKGROUND: Perforator flap techniques with conventional wound dressing have being extensively used in the management of soft-tissue defects. However; the flap's survival rate is not always guaranteed and the wound healing time always long. The aim of this study was to investigate the clinical effectiveness use of a freshly transplanted perforator flap in conjunction with Vacuum-assisted closure (VAC) for better clinical outcomes. METHODS: A prospective, randomized, effectiveness study comparing the clinical outcomes of VAC versus traditional wrap and bandages for the treatment of open wounds that required hospital admission and operative debridement using perforator flaps, was carried out from March 1, 2014 to March 31, 2016 at Wuhan University Zhongnan Hospital...
July 12, 2017: Journal of Tissue Viability
https://www.readbyqxmd.com/read/28734534/elbow-vascularized-composite-allotransplantation-surgical-anatomy-and-technique
#6
Zvi Steinberger, Heng Xu, Nikolas H Kazmers, Stephanie Thibaudeau, Russel G Huffman, L Scott Levin
BACKGROUND: Elbow reconstruction with vascularized composite allotransplantation (VCA) may hold promise in treating end-stage arthritis as no current treatment is both functional and durable. We describe the vascular and gross anatomy of the elbow in the context of VCA procurement and propose a step-by-step surgical technique for human elbow VCA. METHODS: We injected latex in the arterial tree of 16 fresh adult cadaveric upper extremities. We identified and measured arteries and nerves and their branch points relative to the medial epicondyle...
August 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28733749/usefulness-of-the-s-o-clip-for-gastric-endoscopic-submucosal-dissection-with-video
#7
Rintaro Hashimoto, Dai Hirasawa, Tomoyuki Iwaki, Hajime Yamaoka, Kousuke Nihei, Ippei Tanaka, Akimichi Chonan, Kei Takase
BACKGROUND: Endoscopic submucosal dissection (ESD) is technically one of the most complicated endoscopic procedures. Traction methods have been reported to be effective for ESD. A recent study revealed that the S-O clip allowed faster and safer colonic ESD. We assessed the efficacy and safety of gastric ESD with the S-O clip for gastric epithelial neoplasm. METHODS: We performed a retrospective cohort study of patients treated for gastric ESD using the S-O clip between September and November 2016 (SO group, n = 48)...
July 21, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28733733/outcome-of-dilatation-and-predictors-of-failed-dilatation-in-patients-with-acid-induced-corrosive-esophageal-strictures
#8
Chadin Tharavej, Suppa-Ut Pungpapong, Pakkavuth Chanswangphuvana
Outcome of endoscopic dilatation in acid-induced corrosive esophageal stricture is less known. This study aims to determine the outcome of dilatation and predictors of failed dilatation in patients with acid-induced corrosive esophageal stricture. Patients diagnosed of corrosive esophageal strictures were included. Endoscopic dilatation with graded Savary-Gilliard dilator was performed as the first line treatment. Outcome of dilatation was considered favorable when patients were able to swallow solid without intervention at least six months after successful dilatation...
July 21, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28733731/novel-laparoscopic-training-system-with-continuously-perfused-ex-vivo-porcine-liver-for-hepatobiliary-surgery
#9
Wenyan Liu, Xinglong Zheng, Rongqian Wu, Yinbin Jin, Shu Kong, Jianpeng Li, Jianwen Lu, Huan Yang, Xianghua Xu, Yi Lv, Xiaogang Zhang
OBJECTIVE: To introduce a novel laparoscopic training system with a continuously perfused ex-vivo porcine liver for hepatobiliary surgery. BACKGROUND: Existing models for laparoscopic training, such as box trainers and virtual reality simulators, often fail to provide holistic training and real haptic feedback. We have formulated a new training system that addresses these problems. METHODS: Real-Liver Laptrainer consists of a porcine liver, customized mannequin, ex-vivo machine perfusion system, and monitoring software...
July 21, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28733478/growth-and-morbidity-of-extremely-preterm-infants-after-early-full-enteral-nutrition
#10
Christoph Maas, Axel R Franz, Stefanie von Krogh, Jörg Arand, Christian F Poets
OBJECTIVES: To evaluate feasibility and consequences of accelerated feeding advancement on short-term outcomes in extremely low gestational age neonates (ELGANs) who stayed in our institution for >28 days. METHODS: Retrospective single-centre cohort analysis covering the years 2011-2013. Data are presented as median (IQR). RESULTS: Infants '(n=77) birth weight was 745 (640 to 960) g and gestational age at birth 26.7 (25.1 to 27.4) weeks...
July 21, 2017: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/28733176/a-case-of-surgical-delayed-sovranastomotic-perforation-successfully-treated-with-an-over-the-scope-clip-with-video
#11
B Mangiavillano, M Bianchetti, L H Eusebi, A Repici
No abstract text is available yet for this article.
June 23, 2017: Digestive and Liver Disease
https://www.readbyqxmd.com/read/28732299/enterovesical-fistula-a-rare-complication-of-meckel-s-diverticulum-a-case-report
#12
Bourguiba M A, Gharbi M, Ghalleb M, Ben Taher A, Souai F, Bensafta Y, Sayari S, Ben Moussa M
INTRODUCTION: Enterovesical fistulas usually result from diverticulitis, Crohn's disease, or colorectal cancer. A perforated Meckel's diverticulum can exceptionally result in an vesico-diverticulum fistula, as noted in only seven previously reported cases. CASE REPORT: A 35-year old Arabic male, quadriplegic,who presented epigastralgia evolving for a week, associated with abdominal distension and cloudy urine. On examination he was feverish (38.5°C), dehydrated with tenderness in the entire distended abdomen; rectal examination revealed a hypotonic sphincter with no other abnormality...
July 8, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28732270/unexpected-histopathology-of-acute-appendicitis
#13
Mutee Ur Rehman, Felik Paulus, Min Hoe Chew
INTRODUCTION: Appendicular diverticula and associated diverticulitis is a rare disease. Patients present commonly with symptoms of acute appendicitis and require laparoscopic or open surgery. Diagnosis is usually made only on histology. Here, we present a rare case of acute diverticulitis of the appendix. CASE PRESENTATION: A 33-year old gentleman presented with right iliac fossa pain of 3 days duration. On admission, appendicitis was diagnosed on Computerized Tomography (CT) scan and laparoscopic appendicectomy was subsequently performed...
July 10, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28731997/perforated-meckel-s-diverticulum
#14
Janaina Gatto, Jonas Takada, Jose P Otoch, Fernanda Kreve, Francisco S Loss, Everson L A Artifon
We report a patient with diffuse peritonitis due to perforation of Meckel's diverticulum. This patient was referred to the operating room and underwent bowel resection segment encompassing the area of the diverticulum and terminoterminal primary enteroanastomosis on two levels with good evolution. The diverticulum complications are often related to the presence of ectopic mucosa, specially the gastric and pancreatic type. Since preoperative diagnosis is difficult and infrequent, in most cases this anomaly is confirmed only during surgery...
April 2017: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
https://www.readbyqxmd.com/read/28730797/ileal-perforation-following-cetuximab-and-folfiri-chemotherapy-in-a-patient-with-ascending-colon-cancer-with-peritoneal-carcinomatosis
#15
Young Wan Kim
No abstract text is available yet for this article.
May 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28730753/randomized-clinical-trial-of-appendicitis-inflammatory-response-score-based-management-of-patients-with-suspected-appendicitis
#16
M Andersson, B Kolodziej, R E Andersson
BACKGROUND: The role of imaging in the diagnosis of appendicitis is controversial. This prospective interventional study and nested randomized trial analysed the impact of implementing a risk stratification algorithm based on the Appendicitis Inflammatory Response (AIR) score, and compared routine imaging with selective imaging after clinical reassessment. METHOD: Patients presenting with suspicion of appendicitis between September 2009 and January 2012 from age 10 years were included at 21 emergency surgical centres and from age 5 years at three university paediatric centres...
July 21, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28730368/safety-of-cold-polypectomy-for-small-colorectal-neoplastic-lesions-a-prospective-cohort-study-in-japan
#17
Yuichi Shimodate, Motowo Mizuno, Rio Takezawa, Mami Kobayashi, Tatsuhiro Yamazaki, Akira Doi, Naoyuki Nishimura, Hirokazu Mouri, Kazuhiro Matsueda, Hiroshi Yamamoto
BACKGROUND: Cold polypectomy has been widely accepted for removal of small colorectal polyps. However, no large-scale prospective study exists as for its safety in Japan. We investigated this issue in this single-center, prospective cohort study in a total of 1198 colorectal polyps resected with cold polypectomy. PATIENTS AND METHODS: Four hundred and seventy-four patients who underwent cold polypectomy for colorectal neoplastic lesions less than 10-mm diameter between September 2014 and October 2016 were enrolled...
July 20, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28730310/optical-biosensor-optimized-for-continuous-in-line-glucose-monitoring-in-animal-cell-culture
#18
Mircea Tric, Mario Lederle, Lisa Neuner, Igor Dolgowjasow, Philipp Wiedemann, Stefan Wölfl, Tobias Werner
Biosensors for continuous glucose monitoring in bioreactors could provide a valuable tool for optimizing culture conditions in biotechnological applications. We have developed an optical biosensor for long-term continuous glucose monitoring and demonstrated a tight glucose level control during cell culture in disposable bioreactors. The in-line sensor is based on a commercially available oxygen sensor that is coated with cross-linked glucose oxidase (GOD). The dynamic range of the sensor was tuned by a hydrophilic perforated diffusion membrane with an optimized permeability for glucose and oxygen...
July 20, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28730138/ileal-perforation-with-norovirus-gastroenteritis-in-a-3-month-old-infant
#19
Seol Woo Wi, Su Jin Lee, Eun Kyeong Kang, Sung Min Cho
Noroviruses have been recognized as the leading cause of epidemic and sporadic gastroenteritis since the advent of molecular diagnostic technique. They have been documented in 5-31% of pediatric patients hospitalized with gastroenteritis. Although norovirus gastroenteritis is typically mild and self-limited, it causes severe, but sometimes fatal, conditions in the vulnerable population such as immunocompromised patients, young children, and the elderly. Bowel perforation due to norovirus infection is rare. We report a case of small bowel perforation with norovirus gastroenteritis in the infant with Down syndrome during the hospitalization with pneumonia...
June 2017: Pediatric Gastroenterology, Hepatology & Nutrition
https://www.readbyqxmd.com/read/28729154/tremelimumab-as-second-line-or-third-line-treatment-in-relapsed-malignant-mesothelioma-determine-a-multicentre-international-randomised-double-blind-placebo-controlled-phase-2b-trial
#20
Michele Maio, Arnaud Scherpereel, Luana Calabrò, Joachim Aerts, Susana Cedres Perez, Alessandra Bearz, Kristiaan Nackaerts, Dean A Fennell, Dariusz Kowalski, Anne S Tsao, Paul Taylor, Federica Grosso, Scott J Antonia, Anna K Nowak, Maria Taboada, Martina Puglisi, Paul K Stockman, Hedy L Kindler
BACKGROUND: New therapeutic strategies for malignant mesothelioma are urgently needed. In the DETERMINE study, we investigated the effects of the cytotoxic-T-lymphocyte-associated antigen 4 (CTLA-4) monoclonal antibody tremelimumab in patients with previously treated advanced malignant mesothelioma. METHODS: DETERMINE was a double-blind, placebo-controlled, phase 2b trial done at 105 study centres across 19 countries in patients with unresectable pleural or peritoneal malignant mesothelioma who had progressed after one or two previous systemic treatments for advanced disease...
July 17, 2017: Lancet Oncology
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