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https://www.readbyqxmd.com/read/27734108/complications-of-intravascular-catheters-in-icu-definitions-incidence-and-severity-a-randomized-controlled-trial-comparing-usual-transparent-dressings-versus-new-generation-dressings-the-advanced-study
#1
Silvia Calviño Günther, Carole Schwebel, Rebecca Hamidfar-Roy, Agnès Bonadona, Maxime Lugosi, Claire Ara-Somohano, Clémence Minet, Leïla Potton, Jean-Charles Cartier, Aurelien Vésin, Magalie Chautemps, Lenka Styfalova, Stephane Ruckly, Jean-François Timsit
PURPOSE: To describe all post-insertion complications involving most used intravascular access, and to determine whether the use of a new-generation transparent dressing (3M™ IV Advanced) might reduce their number and impact on ICU patient outcomes. METHODS: Patients older than 18, with an expected length of stay ≥48 h and requiring at least one central venous catheter (CVC), arterial catheter (AC), haemodialysis catheter (HDC), pulmonary arterial catheters (PAC) or peripheral venous catheter (PVC) were randomized into two groups: a new-generation transparent dressing, or the hospital's classical transparent dressing, and were followed daily for any infectious and non-infectious complications...
October 12, 2016: Intensive Care Medicine
https://www.readbyqxmd.com/read/27234944/vascular-catheter-colonization-surveillance-based-on-culture-of-needleless-connectors
#2
María Jesús Pérez-Granda, María Guembe, Raquel Cruces, Emilio Bouza
BACKGROUND: Superficial culture has a high negative predictive value in the assessment of catheter tip colonization (CC) and catheter-related bloodstream infection (C-RBSI). However, the process of hub culture requires the hubs to be swabbed, and this carries a risk of dislodging the biofilm. At present, most catheter hubs are closed by needleless connectors (NCs) that are periodically replaced. Our objective was to compare the yield of SC (skin + hub culture) with that of skin + NC culture in the assessment of CC and C-RBSI...
2016: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/27142044/efficacy-of-two-antiseptic-regimens-on-skin-colonization-of-insertion-sites-for-two-different-catheter-types-a-randomized-clinical-trial
#3
Juergen Thomas Lutz, Isabel Victoria Diener, Kerstin Freiberg, Robert Zillmann, Kija Shah-Hosseini, Harald Seifert, Bettina Berger-Schreck, Hilmar Wisplinghoff
PURPOSE: Catheter-related bloodstream infections affect patients in surgical and intensive care settings worldwide, causing complications, aggravation of existing symptoms and increased length of stay. The trial aimed at comparing two registered skin antiseptics with respect to their residual and therefore infection-preventing effects. METHODS: In a parallel, monocentric, prospective, triple-blind, randomized trial the difference in bacterial recolonization of catheter skin sites in central venous (CVC) and epidural catheters (EC) was investigated by comparing two alcoholic-based skin disinfectants...
May 3, 2016: Infection
https://www.readbyqxmd.com/read/26982376/catheter-impregnation-coating-or-bonding-for-reducing-central-venous-catheter-related-infections-in-adults
#4
REVIEW
Nai Ming Lai, Nathorn Chaiyakunapruk, Nai An Lai, Elizabeth O'Riordan, Wilson Shu Cheng Pau, Sanjay Saint
BACKGROUND: The central venous catheter (CVC) is essential in managing acutely ill patients in hospitals. Bloodstream infection is a major complication in patients with a CVC. Several infection control measures have been developed to reduce bloodstream infections, one of which is impregnation of CVCs with various forms of antimicrobials (either with an antiseptic or with antibiotics). This review was originally published in June 2013 and updated in 2016. OBJECTIVES: Our main objective was to assess the effectiveness of antimicrobial impregnation, coating or bonding on CVCs in reducing clinically-diagnosed sepsis, catheter-related blood stream infection (CRBSI), all-cause mortality, catheter colonization and other catheter-related infections in adult participants who required central venous catheterization, along with their safety and cost effectiveness where data were available...
2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/26623068/an-unusual-cause-of-respiratory-failure-in-a-colon-cancer-patient
#5
María Sereno, Francisco Javier Montoro, Carlos Casanova, Gerardo Gutiérrez-Gutiérrez, Joaquín Ojeda, Enrique Sáenz Casado
Permanent central venous catheters (CVC), such as Port-a-Cath®, Hickmann® or PICC®, are widely used in oncology patients for cancer treatment. Thrombosis is a frequent complication that should be ruled out, as it is associated with potentially severe infection and hemodynamic consequences. This is the case report of a male patient who was undergoing chemotherapy for colon cancer. The patient presented with an atrial mass secondary to a CVC-related organized thrombus located inside the atrial cavity. The mass was inducing a massive right-to-left intracardial shunt due to a persistent foramen ovale and signs of respiratory failure that required surgical intervention to remove the intracardial mass...
September 2015: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/26376765/risk-factors-for-central-line-associated-bloodstream-infection-in-patients-with-major-burns-and-the-efficacy-of-the-topical-application-of-mupirocin-at-the-central-venous-catheter-exit-site
#6
Liju Tao, Junyi Zhou, Yali Gong, Wen Liu, Ting Long, Xianhui Huang, Gaoxing Luo, Yizhi Peng, Jun Wu
AIM: The aim of this study was to evaluate the efficacy of the topical administration of mupirocin and other practices in central venous catheter (CVC) care to prevent central line-associated bloodstream infections (CLABSI) in patients with major burns. METHODS: Patients with major burns admitted to a burn ICU were divided into four groups and disinfected at the CVC exit site with single povidone iodine (PVP-I) or PVP-I plus topical mupirocin ointment three times a day or once a day, respectively...
December 2015: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/26367403/new-robbins-device-to-evaluate-antimicrobial-activity-against-bacterial-biofilms-on-central-venous-catheters
#7
Mohamed Amine Mekni, Wafa Achour, Assia Ben Hassen
BACKGROUND: Layouts of biomedical devices were tightly related with the emergence of Staphylococcus epidermidis as a major cause of nosocomial infections because of its ability to form biofilm on the biomaterial surfaces. This fact led researchers to develop in-vitro models to simulate what is really happening during biofilm formation process in order to have a better understanding of this phenomena and then to control it and to resolve the associated problems. The aim of this paper was to develop a homemade dynamic device based on instruments used in clinical practice, easy to mount, with low coast and with no sophisticated features...
March 2015: La Tunisie Médicale
https://www.readbyqxmd.com/read/26362005/central-venous-catheter-repair-is-not-associated-with-an-increased-risk-of-central-line-infection-or-colonization-in-intestinal-failure-pediatric-patients
#8
Claire McNiven, Noah Switzer, Melisssa Wood, Rabin Persad, Marie Hancock, Sarah Forgie, Bryan J Dicken
PURPOSE: The intestinal failure (IF) population is dependent upon central venous catheters (CVC) to maintain minimal energy requirements for growth. Central venous catheter infections (CVCI) are frequent and an independent predictor of intestinal failure associated liver disease. A common complication in children with long-term CVC is the risk of line breakage. Given the often-limited usable vascular access sites in this population, it has been the standard of practice to perform repair of the broken line...
March 2016: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/26058473/detection-of-central-venous-catheter-related-bloodstream-infections-in-haematooncological-patients
#9
Jasmin Rabensteiner, Georg Theiler, Wiebke Duettmann, Ines Zollner-Schwetz, Martin Hoenigl, Thomas Valentin, Eva Leitner, Josefa Luxner, Andrea Grisold, Angelika Valentin, Peter Neumeister, Robert Krause
BACKGROUND: Catheter-related bloodstream infections (CRBSIs) are currently detected in patients with clinically suspicion. The aim of our study was to evaluate whether CRBSIs could be anticipated and detected in a subclinical stage by peptide nucleic acid fluorescence in situ hybridization (PNA FISH) using universal hybridization probes or acridine orange leucocyte cytospin (AOLC) tests in haematooncological patients with central venous catheters (CVCs) in situ. MATERIALS AND METHODS: Peptide nucleic acid fluorescence in situ hybridization and AOLC tests using blood samples from one CVC lumen/port chamber in haematooncological patients were continuously performed...
August 2015: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/25964587/%C3%A2-%C3%A2-f-fdg-pet-ct-imaging-in-patients-with-febrile-neutropenia-and-haematological-malignancies
#10
Vincent Camus, Agathe Edet-Sanson, Michael Bubenheim, Anne Hitzel, Stéphanie Becker, Marion David, Aspasia Stamatoullas, Pascal Lenain, Fabrice Jardin, Nathalie Contentin, Marie Laure Fontoura, Nathalie Cardinael, Sandrine Vaudaux, Sydney Dubois, Hervé Tilly, Pierre Vera, Stéphane Leprêtre
The aim of the present study was to assess the prevalence of hyper-metabolic infection sites revealed by fluorine-18 ((18)F) fluorodeoxyglucose (FDG) positron-emission tomography (PET) combined with computed tomography (CT) in patients with febrile neutropenia (FN). Forty-eight consecutive patients with haematological malignancies and persistent FN (temperature ≥ 38°C and neutrophil count <500 cells/μl for more than two days) as a consequence of intensive chemotherapy were prospectively included. Pathological FDG uptakes identified 31 foci of infections located in the lungs (n=15, 48...
May 2015: Anticancer Research
https://www.readbyqxmd.com/read/25868651/individual-versus-pooled-multiple-lumen-blood-cultures-for-the-diagnosis-of-intravascular-catheter-related-infections
#11
COMPARATIVE STUDY
Alexis Samara Herrera-Guerra, Elvira Garza-González, Michel Fernando Martínez-Resendez, Jorge Martín Llaca-Díaz, Adrián Camacho-Ortiz
BACKGROUND: The current gold standard method for diagnosis of central-line associated bloodstream infections (CLABSIs) requires central venous catheter removal and a positive culture of the CVC tip with a positive peripheral blood culture. STUDY DESIGN: Comparative study. METHODS: We compared individual blood cultures from each catheter lumen versus a pooled-blood culture bottle containing blood samples from every catheter lumen for the diagnosis of CLABSI...
July 1, 2015: American Journal of Infection Control
https://www.readbyqxmd.com/read/25852825/an-engineered-micropattern-to-reduce-bacterial-colonization-platelet-adhesion-and-fibrin-sheath-formation-for-improved-biocompatibility-of-central-venous-catheters
#12
Rhea M May, Chelsea M Magin, Ethan E Mann, Michael C Drinker, John C Fraser, Christopher A Siedlecki, Anthony B Brennan, Shravanthi T Reddy
BACKGROUND: Catheter-related bloodstream infections (CRBSIs) and catheter-related thrombosis (CRT) are common complications of central venous catheters (CVC), which are used to monitor patient health and deliver medications. CVCs are subject to protein adsorption and platelet adhesion as well as colonization by the natural skin flora (i.e. Staphylococcus aureus and Staphylococcus epidermidis). Antimicrobial and antithrombotic drugs can prevent infections and thrombosis-related complications, but have associated resistance and safety risks...
2015: Clinical and Translational Medicine
https://www.readbyqxmd.com/read/25519998/screening-and-treatment-for-staphylococcus-aureus-in-patients-undergoing-hemodialysis-a-systematic-review-and-meta-analysis
#13
REVIEW
Cibele Grothe, Mônica Taminato, Angélica Belasco, Ricardo Sesso, Dulce Barbosa
BACKGROUND: This study was performed to evaluate the effectiveness of surveillance for screening and treatment of patients with chronic kidney disease undergoing hemodialysis and colonized by Staphylococcus aureus. METHODS: A systematic review and meta-analysis were performed. The literature search involved the following databases: the Cochrane Controlled Trials Register, Embase, LILACS, CINAHL, SciELO, and PubMed/Medline. The descriptors were "Staphylococcus aureus", "MRSA", "MSSA", "treatment", "decolonization", "nasal carrier", "colonization", "chronic kidney disease", "dialysis", and "haemodialysis" or "hemodialysis"...
December 18, 2014: BMC Nephrology
https://www.readbyqxmd.com/read/25447733/effectiveness-of-silver-impregnated-central-venous-catheters-for-preventing-catheter-related-blood-stream-infections-a-meta-analysis
#14
REVIEW
Ya-Mei Chen, Ai-Ping Dai, Yan Shi, Zhan-Ju Liu, Mei-Fang Gong, Xiao-Bing Yin
OBJECTIVES: The purpose of this meta-analysis was to examine the effectiveness of silver-impregnated central venous catheters (CVCs) in preventing catheter bacterial colonization and catheter-related blood stream infections (CRBSIs). METHODS: PubMed, Cochrane, and Embase databases were searched up to April 30, 2014. Studies in which other antiseptic reagents were used (e.g., chlorhexidine, octenidine dihydrochloride, urokinase rinses, benzalkonium chloride, rifampin-minocycline) were excluded...
December 2014: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/25426446/infections-caused-by-non-tuberculous-mycobacteria-in-recipients-of-hematopoietic-stem-cell-transplantation
#15
REVIEW
Khalid Ahmed Al-Anazi, Asma M Al-Jasser, Waleed Khalid Al-Anazi
Non-tuberculous mycobacteria (NTM) are acid-fast bacteria that are ubiquitous in the environment and can colonize soil, dust particles, water sources, and food supplies. They are divided into rapidly growing mycobacteria such as Mycobacterium fortuitum, Mycobacterium chelonae, and Mycobacterium abscessus as well as slowly growing species such as Mycobacterium avium, Mycobacterium kansasii, and Mycobacterium marinum. About 160 different species, which can cause community acquired and health care-associated infections, have been identified...
2014: Frontiers in Oncology
https://www.readbyqxmd.com/read/25307004/antibiotic-coated-catheter-to-decrease-infection-pilot-study
#16
Pedro Kurtz, Paula Rosa, Guilherme Penna, Fabricio Braga, Jose Kezen, Luis Eduardo Drumond, Márcia Freitas, Gustavo Almeida, Ronaldo Vegni, Marcelo Kalichsztein, Gustavo Nobre
BACKGROUND AND OBJECTIVES: Nosocomial catheter related bloodstream infections (CR-BSI) increase morbidity and mortality in critically ill patients. Central venous catheters (CVC) coated with rifampin and minocycline (RM) decrease rates of colonization and CR-BSI. However, recent trials challenged the clinical impact of such catheters. We designed this trial to compare rates of colonization and CR-BSI in RM catheters and controls in a cohort of critically ill patients in Brazil. METHODS: Prospective, controlled trial conducted in one medico-surgical ICU...
June 2008: Revista Brasileira de Terapia Intensiva
https://www.readbyqxmd.com/read/25253042/the-use-of-minocycline-rifampin-coated-central-venous-catheters-for-exchange-of-catheters-in-the-setting-of-staphylococcus-aureus-central-line-associated-bloodstream-infections
#17
Anne-Marie Chaftari, Aline El Zakhem, Mohamed A Jamal, Ying Jiang, Ray Hachem, Issam Raad
BACKGROUND: Central venous catheters (CVC) removal and reinsertion of a new CVC in the setting of central line associated bloodstream infections (CLABSI) is not always possible in septic patients. The purpose of this study was to evaluate the outcome of patients with Staphylococcus aureus-CLABSI (SA-CLABSI) who had their CVCs exchanged over guidewire for minocycline/rifampin-coated (M/R)-CVC within seven days of bacteremia. METHODS: Each case was matched with two control patients who had SA-CLABSI and had their CVC removed within seven days and two control patients who had their CVC retained beyond seven days...
2014: BMC Infectious Diseases
https://www.readbyqxmd.com/read/25248485/usefulness-of-endoluminal-catheter-colonization-surveillance-cultures-to-reduce-catheter-related-bloodstream-infections-in-hemodialysis
#18
Patricia Brañas, Enrique Morales, Francisco Ríos, Francisca Sanz, Eduardo Gutiérrez, Nuria Quintanilla, M Angeles Orellana, Mercedes Sánchez, Almudena Rodríguez-Aranda, Fernando Chaves
BACKGROUND: To evaluate the use of surveillance cultures (SCs) to prevent catheter-related bloodstream infections (CRBSIs) in asymptomatic hemodialysis (HD) patients. METHODS: In 2011-2012, we conducted a prospective study of HD patients with tunneled cuffed central venous catheters (TCCs). Colonization of the catheter lumen was assessed every 15 days by inoculating ~5 mL endoluminal blood into aerobic culture bottles. Individual patients were triaged based on SC results: group 1 (negative); group 2 (coagulase-negative Staphylococcus [CoNS] with time-to-positivity (TTP) >14 hours); group 3 (CoNS with TTP ≤14 hours); and group 4 (any microorganism other than CoNS and any TTP)...
November 2014: American Journal of Infection Control
https://www.readbyqxmd.com/read/25088065/bacteriophage-k-antimicrobial-lock-technique-for-treatment-of-staphylococcus-aureus-central-venous-catheter-related-infection-a-leporine-model-efficacy-analysis
#19
Matthew P Lungren, Rodney M Donlan, Ravi Kankotia, Ben E Paxton, Irene Falk, Diana Christensen, Charles Y Kim
PURPOSE: To determine whether a bacteriophage antimicrobial-lock technique can reduce bacterial colonization and biofilm formation on indwelling central venous catheters in a rabbit model. MATERIALS AND METHODS: Cuffed central venous catheters were inserted into the jugular vein of female New Zealand White rabbits under image guidance. Catheters were inoculated for 24 hours with broth culture of methicillin-sensitive Staphylococcus aureus. The inoculum was aspirated, and rabbits were randomly assigned to two equal groups for 24 hours: (i) untreated controls (heparinized saline lock), (ii) bacteriophage antimicrobial-lock (staphylococcal bacteriophage K, propagated titer > 10(8)/mL)...
October 2014: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/25072028/infections-caused-by-acinetobacter-baumannii-in-recipients-of-hematopoietic-stem-cell-transplantation
#20
REVIEW
Khalid Ahmed Al-Anazi, Asma M Al-Jasser
Acinetobacter baumannii (A. baumannii) is a Gram-negative, strictly aerobic, non-fermentative coccobacillus, which is widely distributed in nature. Recently, it has emerged as a major cause of health care-associated infections (HCAIs) in addition to its capacity to cause community-acquired infections. Risk factors for A. baumannii infections and bacteremia in recipients of hematopoietic stem cell transplantation include: severe underlying illness such as hematological malignancy, prolonged use of broad-spectrum antibiotics, invasive instrumentation such as central venous catheters or endotracheal intubation, colonization of respiratory, gastrointestinal, or urinary tracts in addition to severe immunosuppression caused by using corticosteroids for treating graft versus host disease...
2014: Frontiers in Oncology
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