keyword
https://read.qxmd.com/read/38546137/understanding-exososmes-part-3-therapeutic-diagnostic-potential-in-dentistry
#1
REVIEW
Richard J Miron, Nathan E Estrin, Anton Sculean, Yufeng Zhang
Exosomes are the smallest subset of extracellular signaling vesicles secreted by most cells with the ability to communicate with other tissues and cell types over long distances. Their use in regenerative medicine has gained tremendous momentum recently due to their ability to be utilized as therapeutic options for a wide array of various diseases. Over 5000 publications are currently being published on this topic yearly, many of which in the dental space. This extensive review article is the first scoping review aimed at summarizing all therapeutic uses of exosomes in regenerative dentistry...
March 28, 2024: Periodontology 2000
https://read.qxmd.com/read/38514297/a-retrospective-study-of-occlusal-reconstruction-in-patients-with-old-jaw-fractures-and-dentition-defects
#2
JOURNAL ARTICLE
Ming-Chao Ding, Bo-Ya Jing, Jin Shi, Liu Yang, Xiang-Dong Liu, Jing-Fu Wang, Shuang Qu, Jia-Wu Liang, Zi-Hao Tang, Jin-Long Zhao, Lei Tian
PURPOSE: This study evaluated the methods and clinical effects of multidisciplinary collaborative treatment for occlusal reconstruction in patients with old jaw fractures and dentition defects. METHODS: Patients with old jaw fractures and dentition defects who underwent occlusal reconstruction at the Third Affiliated Hospital of Air Force Military Medical University from January 2018 to December 2022 were enrolled. Clinical treatment was classified into 3 phases...
March 11, 2024: Chinese Journal of Traumatology
https://read.qxmd.com/read/38502434/muscle-and-joint-mechanics-during-maximum-force-biting-following-total-temporomandibular-joint-replacement-surgery
#3
JOURNAL ARTICLE
Sarah C Woodford, Dale L Robinson, Jaafar Abduo, Peter V S Lee, David C Ackland
Total temporomandibular joint replacement (TMJR) surgery is the established treatment for severe temporomandibular joint disorders. While TMJR surgery is known to increase mouth-opening capacity, reduce pain and improve quality of life, little is known about post-surgical jaw function during activities of daily living such as biting and chewing. The aim of this study was to use subject-specific 3D bite force measurements to evaluate the magnitude and direction of joint loading in unilateral total TMJR patients and compare these data to those in healthy control subjects...
March 19, 2024: Biomechanics and Modeling in Mechanobiology
https://read.qxmd.com/read/38485626/morpho-functional-analysis-of-the-temporomandibular-joint-following-mandible-first-bimaxillary-surgery-with-mandible-only-patient-specific-implants
#4
JOURNAL ARTICLE
Mirko Bevini, Chiara Gulotta, Ottavia Lunari, Laura Cercenelli, Emanuela Marcelli, Pietro Felice, Achille Tarsitano, Giovanni Badiali
The aim of this study was to evaluate condylar and glenoid fossa remodeling after bimaxillary orthognathic surgery guided by patient-specific mandibular implants. In total, 18 patients suffering from dentofacial dysmorphism underwent a virtually planned bimaxillary mandibular PSI-guided orthognathic procedure. One month prior to surgery, patients underwent a CBCT scan and optical scans of the dental arches; these datasets were re-acquired 1 month and at least 9 months postsurgery. Three-dimensional models of the condyles, glenoid fossae, and interarticular surface space (IASS) were obtained and compared to evaluate the roto-translational positional discrepancy and surface variation of each condyle and glenoid fossa, and the IASS variation...
February 5, 2024: Journal of Cranio-maxillo-facial Surgery
https://read.qxmd.com/read/38468690/development-of-a-test-bench-for-biomechanical-simulation-a-preliminary-study-of-mandibular-forces
#5
JOURNAL ARTICLE
Anas Ben Achour, Florian Apfeld, Günter Lauer, Christian Bräuer, Henry Leonhardt, Adrian Franke, Andreas Lipphaus, Uwe Teicher, Ulrich Witzel, Tom Alexander Schröder
Purpose: The aim of this study is to develop a test bench, which integrates different complexity levels and enables in that way a flexible and dynamic testing for mid and long term intervals as well as testing of maximum loads till implant failure of different osteosynthesis systems on the mandible. Material and Methods: For this purpose, an analysis of the state of the art regarding existing test benches was combined with interviews of clinical experts to acquire a list of requirements. Based on these requirements a design for a modular test bench was developed...
2024: Frontiers in Bioengineering and Biotechnology
https://read.qxmd.com/read/38312958/dentinogenic-ghost-cell-tumour-in-childhood-involving-the-temporomandibular-joint-considerations-and-therapy
#6
JOURNAL ARTICLE
Jan Rustemeyer, Alexander Busch, Klaus Junker
BACKGROUND: Although the uncommon dentinogenic ghost cell tumour (DGCT) is a benign entity, it possesses the ability to cause widespread destruction of the jaws and to recur after bone-preserving therapy. Hence, clear margins should be achieved upon surgery, and reconstruction techniques must often be used to restore osseous defects. However, this can be challenging in cases with involvement of the temporomandibular joint (TMJ), and especially in children. CASE REPORT: We present a case of a DGCT in a 12-year-old boy with wide infiltration of the mandible and the TMJ...
February 2024: Journal of Maxillofacial and Oral Surgery
https://read.qxmd.com/read/38143608/two-cases-of-idiopathic-condylar-resorption-due-to-temporomandibular-joint-tmj-osteoarthritis-remodeled-by-different-treatment-modalities
#7
Syuntaro Nomoto, Takuya Ota, Hideshi Sekine
Condylar resorption is a condition of progressive and significant mandibular head resorption. We treated two patients with condylar resorption caused by temporomandibular joint (TMJ) osteoarthritis. The first patient was a 22-year-old female at the time of the initial examination. She had a history of orthodontic treatment and came to the clinic with a number of symptoms, including difficulty opening the mouth. Idiopathic condylar resorption was diagnosed, an occlusal splint was placed for approximately one year, and the patient was followed up for 12 years...
November 2023: Curēus
https://read.qxmd.com/read/38105820/cross-sectional-study-of-serum-metal-ions-in-patients-with-metal-implants-in-the-maxillofacial-region
#8
JOURNAL ARTICLE
Garima Khandelwal, Ragavi Alagarsamy, Ajoy Roychoudhury, Ongkila Bhutia, A Shariff
PURPOSE: The purpose of the present study was to measure the serum metal ion levels (titanium, cobalt, chromium) in patients who have metal implants in the maxillofacial region. METHODS: The investigators implemented a cross sectional study on patients treated with procedures requiring metal implants for management of maxillofacial trauma, fixation for orthognathic surgery, and total temporomandibular joint replacement (TJR). Inductively coupled plasma mass spectrometry was used as an analytical method to detect metal ions in serum samples...
December 2023: Journal of Maxillofacial and Oral Surgery
https://read.qxmd.com/read/38098369/the-use-of-dynamic-navigation-systems-as-a-component-of-digital-dentistry
#9
REVIEW
W L Tang, X Y Chao, Z Ye, M W Liu, H Jiang
The development of dynamic navigation system (DNS) has facilitated the development of modern digital medicine. In the field of dentistry, the cutting-edge technology is garnering widespread recognition. Based on the principles of 3-dimensional visualization, virtual design, and precise motion tracking, DNS is mainly composed of a computer, a tracking system, specialized tracer instruments, and navigation software. DNS employs a workflow that begins with preoperative data acquisition and imaging data reconstruction, followed by surgical instrument calibration and spatial registration, culminating in real-time guided operations...
December 15, 2023: Journal of Dental Research
https://read.qxmd.com/read/38017429/successful-complete-oral-rehabilitation-of-a-patient-with-osteopetrosis-with-extensive-pre-treatments-bone-grafts-dental-implants-and-fixed-bridges-a-multidisciplinary-case-report
#10
JOURNAL ARTICLE
P Kelk, A Fasth, PLif Holgerson, M Sjöström
BACKGROUND: Osteopetrosis comprises a group of inherited disorders that are rare and result in abnormal bone structure. Bone remodeling is extremely inhibited because osteoclasts are nonfunctional or lacking. This condition causes overgrowth of bone with disappearance of the bone marrow, leading to aplastic anemia; obstruction of nerve passages in the skull leads to blindness and often hearing impairment. In most cases, osteopetrosis results in oral complications such as tooth deformation, hypomineralization, and delayed or absent tooth eruption...
November 28, 2023: BMC Oral Health
https://read.qxmd.com/read/37888178/hst1-gel-ma-scaffold-significantly-promotes-the-quality-of-osteochondral-regeneration-in-the-temporomandibular-joint
#11
JOURNAL ARTICLE
Yiyang Du, Menghan Chen, Jing Jiang, Lei Wang, Gang Wu, Jianying Feng
OBJECTIVE: Our aim was to evaluate the capacity of the human salivary histatin-1-functionalized methacrylic gelatin scaffold to control osteochondral tissue regeneration and repair in vivo in rabbits with major temporomandibular joint dimensional abnormalities. MATERIALS AND METHODS: In order to compare human salivary histatin-1-functionalized methacrylic gelatin scaffolds to the Blank and Gel-MA hydrogel groups, scaffolds were implanted into osteochondral lesions of a critical size (3 × 3 mm) in the anterior region of the condyle of the temporomandibular joint in New Zealand white rabbits...
October 12, 2023: Journal of Functional Biomaterials
https://read.qxmd.com/read/37818530/-implant-restoration-and-stomatognathic-system-rehabilitation
#12
JOURNAL ARTICLE
L Y Peng, X Wang, W Geng, Y C Su
Stomatognathic system rehabilitation (SSR) is an important component of dental implant therapy, involving multiple disciplines and factors. This article focuses on the importance of clinical issues, such as mandibular position, vertical distance, occlusion and temporomandibular joint in SSR, in order to provide reference for dentists in clinical diagnosis and treatment.
October 9, 2023: Zhonghua Kou Qiang Yi Xue za Zhi, Zhonghua Kouqiang Yixue Zazhi, Chinese Journal of Stomatology
https://read.qxmd.com/read/37817790/assessment-of-fully-digitalized-workflow-for-implant-prosthetic-rehabilitation-in-temporomandibular-disorders-patients-a-clinical-study
#13
JOURNAL ARTICLE
Giuseppe Minervini, Rocco Franco, Salvatore Crimi, Manuele Basili, Saurabh Chaturvedi, Marco Cicciù, Alberto Bianchi, Gabriele Cervino
Digitalized workflow eliminates the need for the tray, impression materials, its decontamination, packaging and shipping, pouring with plaster, cast fabrication, mounting in an articulator, reducing storage spaces, and the risks of any loss or fracture of the plaster model is overcome by archiving on the computer. This clinical investigation aimed to evaluate the effectiveness of the fully digitalized rehabilitation [implant-supported prosthesis] method in partially edentulous patients and with TMD, using advanced software...
September 2023: Saudi Dental Journal
https://read.qxmd.com/read/37733214/can-growing-patients-with-end-stage-tmj-pathology-be-successfully-treated-with-alloplastic-temporomandibular-joint-reconstruction-a-systematic-review
#14
REVIEW
Yasir Rehman Khattak, Nabila Ghaffar, Muhammad Assad Gulzar, Sundas Rahim, Faisal Rafique, Zainab Jan, Shaheen Iqbal, Iftikhar Ahmad
INTRODUCTION: The use of alloplastic total temporomandibular joint reconstruction (TMJR) in growing patients is controversial, mainly due to immature elements of the craniomaxillofacial skeleton. The aim of this systematic review was to evaluate the use of alloplastic TMJR in growing patients, focusing on the patient's clinical presentation, surgical and medical history and efficacy of alloplastic TMJR implantation. MATERIALS AND METHODS: The literature search strategy was based on the Population, Intervention, Comparator, Outcomes and Study type (PICOS) framework...
September 21, 2023: Oral and Maxillofacial Surgery
https://read.qxmd.com/read/37729840/computational-modelling-of-the-fossa-component-fixation-associated-with-alloplastic-total-temporomandibular-joint-replacements
#15
JOURNAL ARTICLE
Zhenhao Shen, Pengyu Zhang, Bo Cheng, Feng Liu, Dongmei He
The alloplastic total temporomandibular joint (TMJ) replacement is a complex surgical approach to end-stage TMJ disorders. The fixation of TMJ prostheses remains a critical issue for implant design and performance. For the fossa component, it is generally considered to use fixation screws to achieve tripod stability. However, the fossa may still come loose, and the mechanism remains unknown. A computational framework, consisting of a musculoskeletal model for calculating muscle and TMJ forces, and a finite element model for the fossa fixation simulation, was developed...
September 7, 2023: Journal of the Mechanical Behavior of Biomedical Materials
https://read.qxmd.com/read/37660523/kinematics-of-the-jaw-following-total-temporomandibular-joint-replacement-surgery
#16
JOURNAL ARTICLE
Sarah C Woodford, Dale L Robinson, Jaafar Abduo, Peter V S Lee, David C Ackland
Total temporomandibular joint (TMJ) replacement surgery aims to improve mandibular function, reduce pain and enhance quality of life in patients suffering from end-stage TMJ disorders. Traditional post-operative jaw evaluation is carried out using measurement of maximum interincisal opening distance; however, this can correlate poorly to joint function. The present study aimed to evaluate three-dimensional (3D) jaw motion during border movements and chewing in unilateral total TMJ replacement patients and healthy controls...
July 28, 2023: Journal of Biomechanics
https://read.qxmd.com/read/37630181/customised-implant-for-temporomandibular-joint-new-technique-to-design-and-stress-analysis-to-balance-the-loading-at-both-ends
#17
JOURNAL ARTICLE
Anubhav Tiwari, Ishfaq A Ahmed, Vijay Kumar Gupta, Rakesh Kumar Haldkar, Ivan A Parinov
The temporomandibular joint (TMJ) is a critical joint for the opening and closing of the mouth. The generation of customised TMJs according to individuals' dental anatomy is needed. Currently, the implants available on the market lack consideration of the patient's dental anatomy. This leads to the creation of an imbalance in the reaction forces on both ends of the TMJ. This requires a slight structural change in the design parameters to give a solution. The purpose of this study is to propose a new design that includes the geometry and materials for a TMJ implant...
August 20, 2023: Micromachines
https://read.qxmd.com/read/37624362/design-and-development-of-a-patient-specific-temporomandibular-joint-implant-probing-the-influence-of-bone-condition-on-biomechanical-response
#18
JOURNAL ARTICLE
Anik Banerjee, Bikramjit Basu, Subrata Saha, Amit Roy Chowdhury
Total temporomandibular joint (TMJ) replacement is widely recognized as an effective treatment for TMJ disorders. The long-term stability of TMJ implants depends on two important factors which are design concepts for fixation to anatomical locations in the mandible and bone conditions. Other factors include stress distribution, microstrain in the peri-implant, bone attributes like bone conditions leading to the clinical complications and failures. This study addresses these limitations by examining the influence of patient-specific design concepts and bone conditions on TMJ implant performance...
August 25, 2023: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://read.qxmd.com/read/37533308/total-temporomandibular-joint-reconstruction-prosthesis-in-hemifacial-microsomia-a-systematic-review
#19
REVIEW
H Arif, R Ashraf, F Khan, Y R Khattak, H Nisar, I Ahmad
Hypoplastic asymmetry due to hemifacial microsomia (HFM) often represents the most difficult reconstruction in the craniomaxillofacial clinic. Although autogenous grafts are generally used for temporomandibular joint reconstruction (TMJR), the use of TMJR prostheses is not well established. The aim of this review was to identify, collect and analyse the use of extended TMJR (eTMJR) prostheses in patients with HFM, describing clinical features, surgical procedures and postoperative complications. Online searches of all major databases were performed according to PRISMA guidelines...
August 2, 2023: Orthodontics & Craniofacial Research
https://read.qxmd.com/read/37529522/multidisciplinary-approach-to-patient-specific-implants-psis-a-case-report-and-review-of-literature
#20
Vedha Vivigdha, Murugesan Krishnan, Santhosh Kumar M P, Senthil Murugan P, Preethi Rajamanickam
Orthodontic treatment often faces challenges in achieving proper anchorage. While orthodontic mini-implants have gained popularity, no universally accepted design and insertion protocol exists for these implants. However, their relatively modest failure rate indicates their clinical reliability. To address complex geometries in the maxilla and mandible, patient-specific implants (PSIs) have emerged as a solution. PSI is currently employed in various domains of oral and maxillofacial surgery like temporomandibular joint (TMJ), total joint replacement, reconstruction of the facial skeleton, and orthognathic surgery...
June 2023: Curēus
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