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Medical disease with pregnancy

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https://www.readbyqxmd.com/read/28094840/hypertensive-disorders-in-pregnancy-and-later-dementia-a-swedish-national-register-study
#1
Ellika G Andolf, Gunilla C M Sydsjö, Marie K Bladh, Goran Berg, Surendra Sharma
INTRODUCTION: Our aim was to investigate the rate of vascular dementia and dementia in women with previous hypertensive disorders in pregnancy since white matter lesions of the brain and cardiovascular disease are linked both to dementia and hypertensive disorders in pregnancy. MATERIAL AND METHODS: Prospective population based registry study on all women giving birth in Sweden between 1973- 1975 (284 598). Women with and without hypertensive disorders in pregnancy were identified by means of the Swedish Medical Birth Register and linked to the National Patient Register where data on somatic disease later in life were obtained...
January 17, 2017: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/28087052/contraceptive-practices-of-women-with-complex-congenital-heart-disease
#2
Pamela D Miner, Mary M Canobbio, Dorothy D Pearson, Mary Schlater, Yvonne Balon, Kathryn J Junge, Ami Bhatt, Deena Barber, Michelle J Nickolaus, Adrienne H Kovacs, Philip Moons, Kate Shaw, Susan M Fernandes
Understanding the contraceptive practices of women with complex congenital heart disease (CHD) and providing them individualized contraception counseling may prevent adverse events and unplanned high-risk pregnancies. Given this, we sought to examine the contraceptive practices in women with CHD, describe adverse events associated with contraceptive use, and describe the provision of contraception counseling. Women >18 years were recruited from 2011 to 2014 from 9 adult CHD (ACHD) centers throughout North America...
December 18, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/28086838/clinical-characteristics-of-genital-chlamydia-infection-in-pelvic-inflammatory-disease
#3
Sung Taek Park, Suk Woo Lee, Min Jeong Kim, Young Mo Kang, Hye Min Moon, Chae Chun Rhim
BACKGROUND: Chlamydia infection in acute pelvic inflammatory disease (PID) is associated with serious complications including ectopic pregnancy, tubal infertility, Fitz-Hugh-Curtis syndrome and tubo-ovarian abscess (TOA). This study compared clinical and laboratory data between PID with and without chlamydia infection. METHODS: The medical records of 497 women who were admitted with PID between 2002 and 2011 were reviewed. The patients were divided into two groups (PID with and without chlamydia infection), which were compared in terms of the patients' characteristics, clinical presentation, and laboratory findings, including inflammatory markers...
January 13, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/28079925/pregnancy-outcome-after-rituximab-treatment-before-conception-in-patients-affected-by-severe-pemphigus-vulgaris-superficialis
#4
C Vassallo, S Grassi, E Tagliabue, A Piccolo, V Brazzelli
Pregnancy is rare among patients affected by pemphigus, especially in European countries, mainly because of older patients, lower fertility rates and possible teratogenic risk.(1) Avoidance of immunosuppressive medications during pregnancy has been recommended, but inadequate treatment of pemphigus may increase morbidity and mortality.(2) Corticosteroids remain the first-line agent for treatment of pemphigus in pregnancy when low dosages are sufficient for disease control; however, prednisone and its metabolites crosses the placenta barrier, and high levels in the serum have been associated with adverse fetal outcomes...
January 12, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28079767/primary-gastric-choriocarcinoma-presenting-as-a-pregnancy-of-unknown-location
#5
Alyssa Larish, Amanika Kumar, Sarah Kerr, Carrie Langstraat
BACKGROUND: Pregnancy of unknown location presents a diagnostic challenge, in rare occasions leading to the diagnosis of malignancy. We describe a case of β-hCG-secreting nongestational primary gastric choriocarcinoma presenting as a pregnancy of unknown location. CASE: A 37-year-old woman, gravida 4 para 3013, presented with several days of vaginal bleeding and rising β-hCG level without ultrasound localization of pregnancy. The diagnosis of pregnancy of unknown location was made and methotrexate administered at a β-hCG level of 7,779 milli-international units/mL...
January 9, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28073974/infertile-women-who-screen-positive-for-depression-are-less-likely-to-initiate-fertility-treatments
#6
Natalie M Crawford, Heather S Hoff, Jennifer E Mersereau
STUDY QUESTION: Are infertile women who screen positive for depression less likely to initiate infertility treatments? SUMMARY ANSWER: Infertile women who screen positive for depression are less likely to initiate treatment for infertility. WHAT IS ALREADY KNOWN: Infertility imposes a psychological burden on many couples. Depression and anxiety have been demonstrated in ~40% of infertile women, which is twice that of fertile women. Further, the psychological burden associated with infertility treatment has been cited as a major factor for discontinuation of infertility care...
January 9, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28063544/the-prevention-of-early-onset-neonatal-group-b-streptococcal-disease
#7
Deborah Money, Victoria M Allen
OBJECTIVE: To review the evidence in the literature and to provide recommendations on the management of pregnant women in labour for the prevention of early-onset neonatal group B streptococcal disease. The key revisions in this updated guideline include changed recommendations for regimens for antibiotic prophylaxis, susceptibility testing, and management of women with pre-labour rupture of membranes. OUTCOMES: Maternal outcomes evaluated included exposure to antibiotics in pregnancy and labour and complications related to antibiotic use...
December 2016: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28056855/symptomatic-congenital-cytomegalovirus-disease-following-non-primary-maternal-infection-a-retrospective-cohort-study
#8
Eran Hadar, Elizabeta Dorfman, Ron Bardin, Rinat Gabbay-Benziv, Jacob Amir, Joseph Pardo
BACKGROUND: Scarce data exist about screening, diagnosis and prognosis of non-primary Cytomegalovirus (CMV) during pregnancy. We aimed to examine antenatal diagnosis of maternal non-primary CMV infection and to identify risk factors for congenial CMV disease. METHODS: Retrospective cohort of 107 neonates with congenital symptomatic CMV infection, following either primary (n = 95) or non-primary (n = 12) maternal CMV infection. We compared the groups for the manifestations and severity of congenial CMV disease, as well as for possible factors associated with the risk of developing CMV related infant morbidity...
January 5, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28056758/thrombotic-management-of-antiphospholipid-syndrome-towards-novel-targeted-therapies
#9
Md Asiful Islam, Fahmida Alam, Kah Keng Wong, Mohammad Amjad Kamal, Siew Hua Gan
Antiphospholipid syndrome (APS) is a systemic autoimmune disease characterized by thrombosis and/or pregnancy morbidity with persistent levels of antiphospholipid antibodies (aPLs). The development of thrombosis in APS is mediated by aPLs and contributes to the high mortality rate in APS patients. However, although APS has been reported for more than 30 years, there has been no optimal regimen for its prevention or for the management of thrombosis, mainly because the mainstay treatment strategies for managing APS are not targeted towards aPL-mediated thrombotic pathophysiology...
5, 2017: Current Vascular Pharmacology
https://www.readbyqxmd.com/read/28045917/impact-of-pregestational-weight-and-weight-gain-during-pregnancy-on-long-term-risk-for-diseases
#10
Ulrika Moll, Håkan Olsson, Mona Landin-Olsson
OBJECTIVE: The aim of this study was to analyse the impact of maternal BMI at start of pregnancy and maternal weight gain during pregnancy on the risk of various diseases later in life. METHODS: In a population-based cohort from southern Sweden, women with at least one delivery registered in the Swedish Medical Birth Register ten or more years before answering a health questionnaire were identified (n = 13,608). Complete data were found in 3,539 women. RESULTS: Women with BMI >25 at start of pregnancy had increased risk of developing obesity (OR 21...
2017: PloS One
https://www.readbyqxmd.com/read/28043188/maternal-serum-vitamin-d-and-parathormone-concentrations-during-gestation-and-in-umbilical-cord-blood-pilot-study
#11
Anastasiya Zasimovich, Anna Fijałkowska, Magdalena Chełchowska, Tomasz Maciejewski
OBJECTIVE: We wanted to define levels of vitamin D (25(OH)D), parathormone (PTH), calcium (Ca), phosphorus (P) and the correlations between them during gestation as well as in umbilical cord blood. METHODS: The study included 37 healthy singleton pregnant women in the course of gestation with no medical history concerning systemic diseases, nor with negative obstetrics and gynecological history. Biochemical parameters were determined using commercially available kits...
January 2, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28039625/the-influence-of-maternal-exposure-history-to-virus-and-medicine-during-pregnancy-on-congenital-heart-defects-of-fetus
#12
Qianhong Liang, Wei Gong, Dongming Zheng, Risheng Zhong, Yunjie Wen, Xiaodan Wang
Congenital heart disease (CHD) is the most common birth defect. It is due to dysfunction of the heart and great vessels during embryo development stage, or the channel was not closed after birth. This study focuses on investigating the influence of virus infection and medicine history during pregnancy on the incidence rate of CHD of fetus. We conducted a retrospective birth cohort study of infant born in the maternal and child health hospital of Fanyu district in Guangzhou. Five thousand three hundred eighty one cases with complete medical records, including mothers, fathers, and infants, were enrolled...
December 30, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28033658/multiple-exposures-to-environmental-pollutants-and-oxidative-stress-is-there-a-sex-specific-risk-of-developmental-complications-for-fetuses
#13
REVIEW
Kaïs H Al-Gubory
Medically assisted procreation significantly contributes to an increase in twin pregnancies. One of the major factors contributing to more twin births is the use of fertility treatments. Twin pregnancy is not without a risk for fetal organ development and the health outcome of new-borns, children, and adults. Multiple pregnancies are associated with an increased risk of developmental complications, such as perinatal mortality, premature births, and low birth weight. Oxidative stress is involved in pregnancy disorders such as abortion, intrauterine growth retardation, and prenatal mortality...
December 2016: Birth Defects Research. Part C, Embryo Today: Reviews
https://www.readbyqxmd.com/read/28029218/decreasing-mortality-during-pregnancy-and-for-a-year-after-while-mortality-after-termination-of-pregnancy-remains-high-a-population-based-register-study-of-pregnancy-associated-deaths-in-finland-2001-2012
#14
E Karalis, V-M Ulander, A-M Tapper, M Gissler
OBJECTIVE: To investigate mortality in the non-pregnant fertile female population, and mortality during pregnancy and up to 1 year after the end of pregnancy, in Finland from 2001 to 2012 and compare the results with those of 1987-2000. DESIGN: Retrospective cohort study. SETTING: Finland. POPULATION: 10 427 deceased women of reproductive age (15-49). METHODS: Pregnancy outcomes were categorised into: ongoing pregnancy or birth, miscarriage or ectopic pregnancy and termination of pregnancy...
December 28, 2016: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28028299/gene-expression-in-obstetric-antiphospholipid-syndrome-a-systematic-review
#15
M Muhammad Aliff, S Muhammad Shazwan, M M Nur Fariha, A R Hayati, A R Nur Syahrina, M Maizatul Azma, A H Nazefah, S Jameela, A A Asral Wirda
BACKGROUND: Antiphospholipid syndrome (APS) is a multisystem disease that may present as venous or arterial thrombosis and/or pregnancy complications with the presence of antiphospholipid antibodies. Until today, heterogeneity of pathogenic mechanism fits well with various clinical manifestations. Moreover, previous studies have indicated that genes are differentially expressed between normal and in the disease state. Hence, this study systematically searched the literature on human gene expression that was differentially expressed in Obstetric APS...
December 2016: Malaysian Journal of Pathology
https://www.readbyqxmd.com/read/28018449/congenital-miliary-tuberculosis-in-an-18-day-old-boy
#16
Jue Seong Lee, Chang Hoon Lim, Eunji Kim, Hyunwook Lim, Yoon Lee, Ji Tae Choung, Young Yoo
Congenital tuberculosis (TB) is a rare disease that is associated with high mortality. Mycobacterium tuberculosis, the causative agent, may be transmitted from the infected mother to the fetus by the transplacental route or by aspiration of infected amniotic fluid. Clinical symptoms and signs are not specific. Miliary patterns are the most common findings in the chest X-rays of many infants with congenital TB. In this case, an 18-day-old boy had jaundice on the fifth day of birth, and fever and respiratory distress appeared on the 18th day...
November 2016: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/28013100/the-impact-of-highly-active-antiretroviral-therapy-on-obstetric-conditions-a-review
#17
REVIEW
Hannah M Sebitloane, Dhayendre Moodley
HIV is the leading cause of maternal and neonatal morbidity and mortality in resource constrained countries. Highly active antiretroviral treatment (HAART) initiated in pregnancy has now almost eliminated mother to child transmission of the virus, and is beginning to show the desired effect of reducing HIV related maternal mortality. By modulating host immunological responses HAART has the potential to alter infections during pregnancy, in addition to modifying clinical conditions such as preeclampsia. There is increasing evidence of the benefits of HAART given to pregnant women, however there is paucity of data that distinguishes HIV or HAART as the cause or exacerbation of pre-existing medical conditions or conditions specific to pregnancy...
December 9, 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28009318/indicators-of-phagocytic-component-and-secretory-iga-in-children-with-bronchial-asthma-secondary-to-undifferentiated-connective-tissue-dysplasia
#18
V Semianchuk, L Haridzhuk, O Bobrykovych
Its aim is to improve the diagnostics and treatment of Bronchial Asthma. There were examined 93 children with bronchial asthma at the age of 6-10 years. All patients were diagnosed with partially controlled or uncontrolled clinical course of bronchial asthma and manifestations of undifferentiated connective tissue dysplasia. The control group included 21 practically healthy children of the same age. The diagnosis of bronchial asthma was made, and the clinical course was determined in accordance with the criteria approved by the Order of Ministry of Health of Ukraine of October 08, 2013 No 868 "Unified clinical protocol of primary, secondary (specialized) medical care "Bronchial Asthma in Children" and GINA criteria (updated in 2015)...
November 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28008591/mirror-syndrome-after-fetoscopic-laser-treatment-a-case-report
#19
Ana Maria Simões Brandão, Ana Patrícia Rodrigues Domingues, Etelvina Morais Ferreira Fonseca, Teresa Maria Antunes Miranda, José Paulo Achando Silva Moura
Mirror syndrome is a rare disease with unknown pathophysiology that can be present in different diseases that can cause fetal hydrops. The prognosis is usually bad with a high perinatal mortality. We report an unusual form of mirror syndrome that manifested itself only after a successful treatment for fetal hydrops (caused by twin-twin transfusion syndrome, in Quinteros stage IV) was performed. This syndrome was controlled by medical treatment, and despite the usually bad prognosis seen in these cases, we could extend the pregnancy from the 23rd to the 34th week of gestation, resulting in the birth of 2 live infants...
November 2016: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/28007511/-neonatal-palliative-care-at-home-contribution-of-the-regional-pediatric-palliative-care-team
#20
N Cojean, C Strub, P Kuhn, L Calvel
The "patients' rights and end-of-life care" act, known as the Leonetti law, has allowed implementation of palliative care in neonatology as an alternative to unreasonable therapeutic interventions. A palliative care project can be offered to newborns suffering from intractable diseases. It must be focused on the newborn's quality of life and comfort and on family support. Palliative care for newborns can be provided in the delivery room, in the neonatal unit, and also at home. Going home is possible but requires medical support...
December 19, 2016: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
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