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Presbyopia

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https://www.readbyqxmd.com/read/28780781/multifocal-intraocular-lenses-and-extended-depth-of-focus-intraocular-lenses
#1
Detlev R H Breyer, Hakan Kaymak, Timon Ax, Florian T A Kretz, Gerd U Auffarth, Philipp R Hagen
Presbyopia and cataract patients' desire for increased spectacle independence after surgery is one of the main drivers for the development of multifocal intraocular lenses (MIOLs) and extended depth of focus (EDOF) intraocular lenses (IOLs). As education, biometry, diagnostics, surgical techniques, and MIOL/EDOF IOL designs have improved over the past decade, an increasing number of cataract surgeons have become cataract-refractive surgeons to help address this need. There is not 1 single MIOL/EDOF IOL, however, that suits all patients' needs...
July 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28779882/magnitude-temporal-trends-and-projections-of-the-global-prevalence-of-blindness-and-distance-and-near-vision-impairment-a-systematic-review-and-meta-analysis
#2
Rupert R A Bourne, Seth R Flaxman, Tasanee Braithwaite, Maria V Cicinelli, Aditi Das, Jost B Jonas, Jill Keeffe, John H Kempen, Janet Leasher, Hans Limburg, Kovin Naidoo, Konrad Pesudovs, Serge Resnikoff, Alex Silvester, Gretchen A Stevens, Nina Tahhan, Tien Y Wong, Hugh R Taylor
BACKGROUND: Global and regional prevalence estimates for blindness and vision impairment are important for the development of public health policies. We aimed to provide global estimates, trends, and projections of global blindness and vision impairment. METHODS: We did a systematic review and meta-analysis of population-based datasets relevant to global vision impairment and blindness that were published between 1980 and 2015. We fitted hierarchical models to estimate the prevalence (by age, country, and sex), in 2015, of mild visual impairment (presenting visual acuity worse than 6/12 to 6/18 inclusive), moderate to severe visual impairment (presenting visual acuity worse than 6/18 to 3/60 inclusive), blindness (presenting visual acuity worse than 3/60), and functional presbyopia (defined as presenting near vision worse than N6 or N8 at 40 cm when best-corrected distance visual acuity was better than 6/12)...
August 2, 2017: Lancet Global Health
https://www.readbyqxmd.com/read/28754903/suppression-of-presbyopia-progression-with-pirenoxine-eye-drops-experiments-on-rats-and-non-blinded-randomized-clinical-trial-of-efficacy
#3
Yukari Tsuneyoshi, Akihiro Higuchi, Kazuno Negishi, Kazuo Tsubota
Various methods can correct presbyopia, but all require devices or surgeries. Recently, supplements or warming devices to relieve presbyopic symptoms have been developed, but no eye drops have been developed. We screened certain compounds possibly related to lens degeneration and identified pirenoxine, which has been used for cataracts, as a possible new pharmacologic treatment for presbyopia. We first researched the anti-presbyopic activity of pirenoxine in rats. The lens elasticity significantly (p = 0...
July 28, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28739381/role-of-parafovea-in-blur-perception
#4
Abinaya Priya Venkataraman, Aiswaryah Radhakrishnan, Carlos Dorronsoro, Linda Lundström, Susana Marcos
The blur experienced by our visual system is not uniform across the visual field. Additionally, lens designs with variable power profile such as contact lenses used in presbyopia correction and to control myopia progression create variable blur from the fovea to the periphery. The perceptual changes associated with varying blur profile across the visual field are unclear. We therefore measured the perceived neutral focus with images of different angular subtense (from 4° to 20°) and found that the amount of blur, for which focus is perceived as neutral, increases when the stimulus was extended to cover the parafovea...
September 2017: Vision Research
https://www.readbyqxmd.com/read/28732606/visual-performance-after-bilateral-implantation-of-2-new-presbyopia-correcting-intraocular-lenses-trifocal-versus-extended-range-of-vision
#5
Gaspare Monaco, Mariangela Gari, Fabio Di Censo, Andrea Poscia, Giada Ruggi, Antonio Scialdone
PURPOSE: To compare the visual outcomes and quality of vision of 2 new diffractive multifocal intraocular lenses (IOLs) with those of a monofocal IOL. SETTING: Fatebenefratelli e Oftalmico Hospital, Milan, Italy. DESIGN: Prospective case series. METHODS: Patients had bilateral cataract surgery with implantation of a trifocal IOL (Panoptix), an extended-range-of-vision IOL (Symfony), or a monofocal IOL (SN60WF). Postoperative examinations included assessing distance, intermediate, and near visual acuity; binocular defocus; intraocular and total aberrations; point-spread function (PSF); modulation transfer function (MTF); retinal straylight; and quality-of-vision (QoV) and spectacle-dependence questionnaires...
June 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28730093/a-systematic-review-of-pseudophakic-monovision-for-presbyopia-correction
#6
REVIEW
Georgios Labiris, Aspa Toli, Aslin Perente, Panagiota Ntonti, Vassilios P Kozobolis
A systematic review of the recent literature regarding pseudophakic monovision as a reliable methods for presbyopia correction was performed based on the PubMed, MEDLINE, Nature and the American Academy of Ophthalmology databases in July 2015 and data from 18 descriptive and 12 comparative studies were included in this narrative review. Pseudophakic monosvision seems to be an effective method for presbyopia with high rates of spectacles independence and minimal dysphotopsia side-effects, that should be considered by the modern cataract surgeons...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28708006/a-near-visual-acuity-test-for-dentists
#7
P Perrin, M Eichenberger, K W Neuhaus, A Lussi
Unimpaired near vision is crucial in dentistry, but appropriate visual tests at dental working distance are not publicly available. The aim of this study was to validate a novel visual triage test for dentists that is easy to use and freely available. The near visual acuity at 300 mm of 106 dental professionals (aged 21-65 years) was assessed with 1) a validated near visual test for scientific purposes miniaturized on a microfilm; 2) an experimental test using a US $5 bill, in which the first five words of each line in the Lincoln Memorial frieze had to be read under a dental operating light...
July 14, 2017: Operative Dentistry
https://www.readbyqxmd.com/read/28674958/monovision-versus-multifocality-for-presbyopia-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#8
REVIEW
Lidija Kelava, Hrvoje Barić, Mladen Bušić, Ivan Čima, Vladimir Trkulja
INTRODUCTION: Refractive surgery in presbyopia tends to achieve spectacle independence with minimal optical disturbances. We compared monovision to multifocality procedures regarding these outcomes. METHODS: We conducted a systematic review of published (till November 21, 2016) randomized controlled trials (RCTs) comparing any monovision to any multifocality method or comparing different monovision/multifocality methods to each other that enabled direct or indirect comparisons between particular monovision and particular multifocality procedures in presbyopic patients undergoing cataract-related or unrelated surgery in respect to spectacle independence, unaided binocular visual acuity (VA), contrast sensitivity (CS), and adverse events...
July 3, 2017: Advances in Therapy
https://www.readbyqxmd.com/read/28674696/accommodative-intraocular-lenses-where-are-we-and-where-we-are-going
#9
REVIEW
Jorge L Alió, Jorge L Alió Del Barrio, Alfredo Vega-Estrada
Presbyopia still remains the last frontier of refractive surgery. Its surgical management is under constant evolution due to the limitations that exist today with respect to its management, which is probably in relation with the multifactorial basis in which presbyopia is clinically developed in the human. Until currently, virtually all surgical techniques that have been proposed for its correction are based on the induction of pseudoaccommodation in the presbyopic eye, including multifocality. However, the real restoration of accommodation is more complex, and it has been tried by the use of different, so called, "accommodative" pseudophakic intraocular lenses (AIOL)...
2017: Eye and Vision (London, England)
https://www.readbyqxmd.com/read/28658954/preparation-and-characterization-of-biomimetic-%C3%AE-lens-crystallins-using-single-chain-polymeric-nanoparticles
#10
Jue Liang, Jessica J Struckhoff, Paul D Hamilton, Nathan Ravi
Presbyopia, the inability to focus at arm's length, and cataracts that cloud vision are associated primarily with changes in the mechanical and optical properties of the lens. The optical properties, particularly the refractive index, of the human lens originate from the cytoplasm of the lens fiber, which contains a highly concentrated solution (∼40%) of globular proteins referred to as α, β, and γ crystallins, of which β is the most abundant. In this study, we focus on the synthesis and characterization of a β-crystallin biomimetic in an effort to understand and develop treatments for presbyopia and cataract...
July 24, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28657533/-the-ametrop%C3%A3-as-updated-review-for-non-ophthalmologists-physicians
#11
REVIEW
Virgilio Galvis, Alejandro Tello, Oscar Blanco, Andrea N Laiton, Marion R Dueñas, Priscila Alejandra Hidalgo
Refractive errors are caused by a decoupling of the power of convergence of the eye lens, the cornea and lens, which make the rays reaching the eye to focus and generate an image, and the retina, which is the biological photosensitive screen where the image will be transformed into a nerve impulse. These defects include myopia, hyperopia and astigmatism. Presbyopia can also be considered a refractive defect, but of special features, since only affects near vision in patients older than 40 years. By altering the quality of the focused image on the most sensitive area of the retina (the macula), they decrease visual acuity...
2017: Revista de la Facultad de Ciencias Médicas
https://www.readbyqxmd.com/read/28650131/accommodating-intraocular-lenses
#12
Jay S Pepose, Joshua Burke, Mujtaba Qazi
With an explosive increase in the worldwide prevalence of presbyopia, development of an accommodating intraocular lens (IOL) with expansive accommodative amplitude remains the holy grail in lens-based refractive surgery. A dynamic change in the dioptric power of the eye can be accomplished by various strategies alone or in combination, including changes in the position, shape, or refractive index of a single- or dual- optic IOL. This article reviews the cumulative advances in these various lens designs, along with clinical outcomes and complications of those that have been implanted...
July 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28624312/non-lens-based-surgical-techniques-for-presbyopia-correction
#13
R Bilbao-Calabuig, F Llovet-Osuna
INTRODUCTION: Presbyopia is the most prevalent refractive error. With a progressive aging population, its surgical correction is an important challenge for the ophthalmology community, as well as the millions of patients who suffer from it, and who are increasingly demanding alternatives to its correction with glasses or contact lenses. MATERIAL AND METHODS: A review is presented with a synthesised discussion on the pathophysiological theories of presbyopia and an updated and analytical description of the non-lens involvement surgical techniques used to treat presbyopia...
June 14, 2017: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/28619486/extended-depth-of-focus-contact-lenses-vs-two-commercial-multifocals-part-2-visual-performance-after-1-week-of-lens-wear
#14
Ravi C Bakaraju, Daniel Tilia, Jennifer Sha, Jennie Diec, Jiyoon Chung, Danny Kho, Shona Delaney, Anna Munro, Varghese Thomas
PURPOSE: To compare the visual performance of prototype contact lenses designed via deliberate manipulation of higher-order spherical aberrations to extend-depth-of-focus with two commercial multifocals, after 1 week of lens wear. METHODS: In a prospective, participant-masked, cross-over, randomized, 1-week dispensing clinical-trial, 43 presbyopes [age: 42-63 years] each wore AIROPTIX Aqua multifocal (AOMF), ACUVUE OASYS for presbyopia (AOP) and extended-depth-of-focus prototypes (EDOF) appropriate to their add requirements...
June 12, 2017: Journal of Optometry
https://www.readbyqxmd.com/read/28617724/intracorneal-inlays-for-the-correction-of-presbyopia
#15
Perry S Binder
The current nonsurgical approaches for the correction of presbyopia are spectacles or contact lenses or the use of pharmaceuticals to create an artificial pupil and/or to stimulate residual accommodation. Refractive surgical procedures use a monovision approach and/or a multifocal corneal laser ablation with or without the induction of negative spherical aberration to improve near vision. More recently, new surgical approaches include intracorneal inlays. Inlay approaches include increasing corneal curvature alone, implanting a multifocal inlay, or by implanting a small aperture device that functions as a pinhole to restore unaided near and intermediate visual acuity...
June 14, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28608800/a-novel-laser-refractive-surgical-treatment-for-presbyopia-optics-based-customization-for-improved-clinical-outcome
#16
Bojan Pajic, Brigitte Pajic-Eggspuehler, Joerg Mueller, Zeljka Cvejic, Harald Studer
Laser Assisted in Situ Keratomileusis (LASIK) is a proven treatment method for corneal refractive surgery. Surgically induced higher order optical aberrations were a major reason why the method was only rarely used to treat presbyopia, an age-related near-vision loss. In this study, a novel customization algorithm for designing multifocal ablation patterns, thereby minimizing induced optical aberrations, was used to treat 36 presbyopic subjects. Results showed that most candidates went from poor visual acuity to uncorrected 20/20 vision or better for near (78%), intermediate (92%), and for distance (86%) vision, six months after surgery...
June 13, 2017: Sensors
https://www.readbyqxmd.com/read/28606456/extended-depth-of-focus-contact-lenses-vs-two-commercial-multifocals-part-1-optical-performance-evaluation-via-computed-through-focus-retinal-image-quality-metrics
#17
Ravi C Bakaraju, Klaus Ehrmann, Arthur Ho
PURPOSE: To compare the computed optical performance of prototype lenses designed using deliberate manipulation of higher-order spherical aberrations to extend depth-of-focus (EDOF) with two commercial multifocals. METHODS: Emmetropic, presbyopic, schematic eyes were coupled with prototype EDOF and commercial multifocal lenses (Acuvue Oasys for presbyopia, AOP, Johnson & Johnson & Air Optix Aqua multifocal, AOMF, Alcon). For each test configuration, the through-focus retinal image quality (TFRIQ) values were computed over 21 vergences, ranging from -0...
June 9, 2017: Journal of Optometry
https://www.readbyqxmd.com/read/28602334/intraindividual-comparative-analysis-of-the-visual-performance-after-cataract-surgery-with-implantation-of-a-trifocal-and-a-bifocal-intraocular-lens
#18
Ghada Al-Khateeb, Mehdi Shajari, Thomas Kohnen
Presbyopia-treating intraocular lenses (IOLs) are now widely available and offer high predictability at all distances, better visual outcomes, and high patient satisfaction. In most patients, the same multifocal IOL is implanted bilaterally. In certain circumstances, such as during complex surgeries, it is important to be prepared with a backup plan to maintain surgical expectations. We report 3 patients who had femtosecond laser-assisted cataract surgeries in both eyes. The complicated eye had implantation of a bifocal IOL and the fellow eye of a trifocal IOL...
May 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28602333/resident-and-young-physician-experience-with-complex-cataract-surgery-and-new-cataract-and-refractive-technology-results%C3%A2-of%C3%A2-the%C3%A2-ascrs-2016-young-eye%C3%A2-surgeons%C3%A2-survey
#19
Julie M Schallhorn, Jessica B Ciralsky, Elizabeth Yeu
A survey was offered to attendees of the 2016 annual meeting of the American Society of Cataract and Refractive Surgery (ASCRS) as well as online to ASCRS members. Of the 429 self-identified surgeons in training or those with fewer than 5 years in practice, 83% had performed complex cataract surgery using iris expansion devices or capsular tension rings (63%) and 70% had implanted a toric intraocular lens (IOL). A minority of respondents had performed laser-assisted cataract surgery (27%) or implanted presbyopia-correcting IOLs (39%), and only half (50%) had performed laser vision correction (LVC)...
May 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28602323/bifocal-nondiffractive-intraocular-lens-for%C3%A2-enhanced-depth-of-focus-in-correcting-presbyopia-clinical-evaluation
#20
Efstathios Vounotrypidis, Raphael Diener, Christian Wertheimer, Thomas Kreutzer, Armin Wolf, Siegfried Priglinger, Wolfgang J Mayer
PURPOSE: To assess the clinical outcomes and patient satisfaction after bilateral cataract surgery with implantation of a bifocal refractive enhanced depth of focus intraocular lens (IOL) with a low near addition (add). SETTING: Department of Ophthalmology, Ludwig-Maximilians-University Munich, Munich, Germany. DESIGN: Prospective longitudinal case series. METHODS: Eyes with bilateral age-related cataract and corneal astigmatism of less than 1...
May 2017: Journal of Cataract and Refractive Surgery
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