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https://www.readbyqxmd.com/read/29668050/long-term-outcome-of-selective-neurectomy-for-refractory-periocular-synkinesis
#1
Martinus M van Veen, Joseph R Dusseldorp, Tessa A Hadlock
OBJECTIVE: The objective of this study was to investigate the long-term effect and treatment stability of selective neurectomy for refractory periocular synkinesis. METHODS: We performed a retrospective review of all patients treated with highly selective neurectomy for refractory periocular synkinesis between August 2009 and August 2015. Primary outcome was time to recommencing treatment for periocular synkinesis. Palpebral fissure width was measured preoperatively, postoperatively, and at long-term ( > 2...
April 18, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29666119/depot-specific-characteristics-of-adipose-tissue-derived-stromal-cells-in-thyroid-associated-orbitopathy
#2
Janice Siu Chong Wong, Wai Kit Chu, Benjamin Fuk-Loi Li, Chi-Pui Pang, Kelvin Kam-Lung Chong
BACKGROUND: Thyroid-associated orbitopathy (TAO) causes inflammatory fibroproliferation of periocular connective tissues. We compared adipose tissue-derived stem/stromal cells (ADSCs) from three adipose depots of each patient with TAO on mesenchymal, myofibrogenic, adipogenic properties and associated hyaluronan (HA) synthesis. METHODS: ADSCs were generated from periocular (eyelid, orbital) and subcutaneous (abdominal) adipose tissues of three patients with TAO...
April 17, 2018: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29663676/a-single-center-pilot-study-evaluating-a-novel-trihex-peptide-and-botanical-containing-eye-treatment-compared-to-baseline
#3
Alex Reivitis, Kian Karimi, Chester Griffiths, Ashley Banayan
BACKGROUND: Topical treatments containing tripeptide and hexapeptide (TriHex technology) have been proven to contribute to youthful skin by clearing the extracellular matrix and stimulating collagen and elastin production. OBJECTIVE: Evaluate the efficacy of a novel eye treatment containing TriHex peptides and other synergistic ingredients for the daily treatment of fine lines/crow's feet around the eyes, under eye hollowing, under eye bags, and dark circles. PATIENTS/METHODS: In this study, 10 subjects (9 female and 1 male) aged 30-60 of Fitzpatrick skin type I, II, or III were selected to use an eye treatment containing TriHex peptides and active botanicals (Alastin Restorative Eye Treatment with TriHex Technology™, ALASTIN Skincare, Inc...
April 16, 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29660784/relationship-between-neural-crest-cell-specification-and-rare-ocular-diseases
#4
REVIEW
Monica Akula, Jeong Won Park, Judith A West-Mays
Development of the eye is closely associated with neural crest cell migration and specification. Eye development is extremely complex, as it requires the working of a combination of local factors, receptors, inductors, and signaling interactions between tissues such as the optic cup and periocular mesenchyme (POM). The POM is comprised of neural crest-derived mesenchymal progenitor cells that give rise to numerous important ocular structures including those tissues that form the optic cup and anterior segment of the eye...
April 16, 2018: Journal of Neuroscience Research
https://www.readbyqxmd.com/read/29660509/glycosylation-enhanced-biocompatibility-of-the-supramolecular-hydrogel-of-an-anti-inflammatory-drug-for-topical-suppression-of-inflammation
#5
Taotao Xiong, Xianglian Li, Yanfang Zhou, Qianqian Song, Renshu Zhang, Lei Lei, Xingyi Li
Intravitreal/periocular injection of triamcinolone acetonide (TA) suspension is a common uveitis treatment, but it displays a high risk for serious side effects (e.g., high intraocular pressure, retinal toxicity). We report here an intravitreally injectable thermosensitive glycosylated TA (TA-SA-Glu) hydrogel, formed by covalently conjugating glucosamine (Glu) with succinate TA (TA-SA), for treating uveitis. The TA-SA-Glu hydrogelator forms a supramolecular hydrogel spontaneously in aqueous solution with a minimal gelation concentration of 0...
April 13, 2018: Acta Biomaterialia
https://www.readbyqxmd.com/read/29651818/effects-on-periocular-tissues-after-proton-beam-radiation-therapy-for-intraocular-tumors
#6
Youn Joo Choi, Tae Wan Kim, Suzy Kim, Hokyung Choung, Min Joung Lee, Namju Kim, Sang In Khwarg, Young Suk Yu
BACKGROUND: To present our experience on orbital and periorbital tissue changes after proton beam radiation therapy (PBRT) in patients with intraocular tumors, apart from treatment outcomes and disease control. METHODS: Medical records of 6 patients with intraocular tumors who had been treated with PBRT and referred to oculoplasty clinics of two medical centers (Seoul National University Hospital and Seoul Metropolitan Government-Seoul National University Boramae Medical Center) from October 2007 to September 2014 were retrospectively reviewed...
April 16, 2018: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29628850/development-of-postoperative-central-anticholinergic-syndrome-due-to-low-dose-intravenous-fentanyl
#7
Hojae Cho, Jiyeon Kim
A 37-year-old female patient, 57 kg and 160 cm, underwent laparoscopic appendectomy. In the recovery room, fentanyl 100 mcg was intravenously administered for pain control. Three minutes after the administration, the patient developed intense and uncontrolled myoclonus, lower limb rigidity, agitation, aphasia, and periocular and neck swelling. The myoclonus and rigidity were suspected to be due to the opioid administration, and thus, naloxone was administered, but the symptoms were not improved. The patient's symptoms continued until the patient received administration of physostigmine...
April 2018: Saudi Journal of Anaesthesia
https://www.readbyqxmd.com/read/29607622/ischemic-oculomotor-nerve-palsy-due-to-hyaluronic-acid-filler-injection
#8
In Ho Bae, Min Sung Kim, Hoon Choi, Chan Ho Na, Bong Seok Shin
Hyaluronic acid (HA) is the most popular agent today for intradermal injections to improve wrinkles and other cosmetic defects. Ischemic necrosis due to injection of HA is one of the serious complications. Because there are many vascular branches around the nose, caution and care should be given during facial filler injection. Although the incidence is rare, blindness and permanent visual loss may occur. We describe a 29-year-old woman presented with painful erythematous swelling with violaceous patch on right periocular area and glabella after HA filler injection...
April 1, 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29587486/cyberknife-radiotherapy-for-orbital-metastases-a-single-center-experience-on-24-lesions
#9
Giulia Riva, Matteo Augugliaro, Gaia Piperno, Annamaria Ferrari, Elena Rondi, Sabrina Vigorito, Delia Ciardo, Roberto Orecchia, Barbara Alicja Jereczek-Fossa
OBJECTIVES: To evaluate the feasibility, in terms of acute toxicity and symptom control, of CyberKnife (Accuray, Sunnyvale, CA)-based stereotactic radiotherapy (CyberKnife-SRT) for metastatic orbital lesions. METHODS: This retrospective study included patients with symptomatic metastases wholly located within the orbit. Palliative radiation treatment was performed using CyberKnife image-guided technology. Gross tumor volume was defined on a pre-radiotherapy magnetic resonance imaging...
March 1, 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/29580977/difluprednate-for-the-treatment-of-uveitic-cystoid-macular-edema
#10
Julie M Schallhorn, Katherine M Niemeyer, Erica N Browne, Parth Chhetri, Nisha R Acharya
PURPOSE: To describe clinical outcomes associated with the use of topical difluprednate in treating uveitic cystoid macular edema. DESIGN: Retrospective, interventional case series. METHODS: Setting: Medical record review in a tertiary care uveitis center. PATIENT POPULATION: 58 patients (72 eyes) with uveitic cystoid macular edema (CME) treated with difluprednate 0.05% ophthalmic solution between June 2012 and May 2016...
March 23, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29565715/dacryoadenitis-due-to-gonococcal-conjunctivitis-complicated-by-corneal-perforation
#11
Thomas L Jenkins, Matthew M Zhang, Neal S Patel, Alison B Huggins, Jacqueline R Carrasco
Adnexal and periocular involvement in Neisseria gonorrhoeae (NG) infection is rare. This report describes the case of a patient with a delayed diagnosis of gonococcal dacryoadenitis with contiguous conjunctivitis and corneal involvement. She underwent extensive inpatient laboratory and infectious workup but rapidly progressed to corneal perforation requiring emergent penetrating keratoplasty prior to a positive culture confirming the diagnosis. To date, this is the first reported case of ophthalmologic NG infection with associated conjunctivitis, dacryoadenitis, and corneal perforation...
March 22, 2018: Orbit
https://www.readbyqxmd.com/read/29552271/ocular-injury-in-cosmetic-laser-treatments-of-the-face
#12
REVIEW
Amy Huang, Arianna Phillips, Tony Adar, Andrea Hui
BACKGROUND: The eye is a vulnerable and commonly injured organ in cosmetic laser procedures of the face. Treatment of the eyelids and periorbital areas increases this risk, especially when ocular protection devices are not used or are removed during the procedure. A study has shown that injury from laser epilation of the periocular areas is one of the most common causes of litigation in cutaneous laser surgery. OBJECTIVE: The goal of this review is to determine the causes of ocular injury in cosmetic laser procedures and derive lessons on critical safety elements to prevent future injury...
February 2018: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/29547466/dermalive-facial-filler-granulomas-masquerading-as-neurofibromas
#13
Natalie Wolkow, Frederick A Jakobiec, Michael K Yoon
A 56-year-old woman presented with periocular nodules that were clinically suspected to be neurofibromas. Histopathologic examination of excised nodules revealed a pronounced granulomatous reaction to a foreign material that was composed of glossy polygonal palely eosinophilic fragments. These fragments were outlined in red with Masson trichrome, stained gray with the elastic stain, and were uniformly red with Gomori methenamine silver staining. The histopathologic appearance was consistent with a granulomatous reaction to Dermalive facial filler...
March 14, 2018: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29535373/propeller-flaps-in-eyelid-reconstruction
#14
Saul N Rajak, Shyamala C Huilgol, Masahiro Murakami, Dinesh Selva
PURPOSE: Propeller flaps are island flaps that reach the recipient site through an axial rotation. The flap has a subcutaneous pedicle on which it pivots, thereby resembling a helicopter propeller. We present our series of propeller flaps for the reconstruction of large eyelid defects. METHODS: This is a retrospective review of the clinical case notes of eight patients that underwent tumour excision with reconstruction with a cutaneous propeller flap supplied by a non-perforator orbicularis pedicle between July and December 2016...
March 14, 2018: Eye
https://www.readbyqxmd.com/read/29533279/human-papillomavirus-driven-squamous-lesions-high-risk-genotype-found-in-conjunctival-papillomas-dysplasia-and-carcinoma
#15
Amanda B Moyer, Jordan Roberts, Randall J Olsen, Patricia Chévez-Barrios
BACKGROUND: Human papillomavirus (HPV) is a causative agent for intraepithelial squamous neoplasms, particularly on mucosal surfaces. HPV has a well-established association with squamous cell carcinoma (SCC) of the oropharynx and genital tract, and recent studies suggest a potential role in ocular and periocular squamous neoplasms. Multiple high-risk HPV genotypes are associated with histologically similar squamous neoplasms, and some HPV genotypes have been differentially associated with high- or low-grade lesions...
March 6, 2018: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/29515375/cell-behaviors-during-closure-of-the-choroid-fissure-in-the-developing-eye
#16
Gaia Gestri, Naiara Bazin-Lopez, Clarissa Scholes, Stephen W Wilson
Coloboma is a defect in the morphogenesis of the eye that is a consequence of failure of choroid fissure fusion. It is among the most common congenital defects in humans and can significantly impact vision. However, very little is known about the cellular mechanisms that regulate choroid fissure closure. Using high-resolution confocal imaging of the zebrafish optic cup, we find that apico-basal polarity is re-modeled in cells lining the fissure in proximal to distal and inner to outer gradients during fusion...
2018: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/29503782/missing-globe-a-case-of-severe-head-trauma-eyelid-laceration-and-traumatic-enucleation
#17
Joobin Khadamy, Pardis Khademi, Mohsen Kashkouli
We report an unusual periocular injury in a 19-year-old motorcycle rider during an accident. The patient had lacerations on the right upper and lower eyelids and the globe was enucleated en bloc. Despite disorganization of the eyelids and orbit, reconstruction of the eyelids and anophthalmic socket was successful. The primary reconstruction of the anophthalmic socket in the traumatic enucleation is a real challenge, especially when the conjunctival and the orbital tissues are missing or disorganized. It is proposed to utilize the optic nerve regeneration techniques in the cases of traumatic enucleation when the globe is intact...
December 26, 2017: Curēus
https://www.readbyqxmd.com/read/29484009/peri-and-intraocular-mutilating-advanced-squamous-cell-carcinoma-monsters-inside-your-body
#18
Georgi Tchernev, Torello Lotti, Ilia Lozev, Georgi Konstantinov Maximov, Uwe Wollina
Periocular malignancies represent between 5% and 10% of all types of skin cancers. The incidence of eyelid (but also the periocular located) malignancies seems to differ in distribution across the continents. The incidence of eyelid tumours (but also the periocular located tumours) in a predominantly white population determined that BCC is the most common malignant periocular eyelid tumour in whites. This finding has been replicated consistently throughout the literature, with BCC representing 85-95% of all eyelid malignancies, SCC representing 3...
January 25, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29484007/locally-advanced-basal-cell-carcinoma-with-intraocular-invasion
#19
Georgi Tchernev, Torello Lotti, Ilia Lozev, Georgi Konstantinov Maximov, Uwe Wollina
We present a 103 - year - old patient, with duration of complaints of about ten years. The initial complaint had been presented as a small nodule, located on the eyebrow, which subsequently ulcerated and encompassed larger regions of the upper and lower eyelids. For the past three years, the patient also had complaints of a worsening of his vision, without seeking for medical help. Within the dermatological examination, an intraocular and periocular localised tumour was established, characterised by a raised peripheral edge and central ulceration...
January 25, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29475902/-in-vivo-analysis-of-prostaglandins-induced-ocular-surface-and-periocular-adnexa-modifications-in-patients-with-glaucoma
#20
REVIEW
Silvio DI Staso, Luca Agnifili, Sara Cecannecchia, Angela DI Gregorio, Marco Ciancaglini
BACKGROUND/AIM: Prostaglandin analogues (PGAs) are a first-line medical treatment for glaucoma because of their powerful intraocular pressure (IOP) lowering effect, few systemic side-effects (SEs), and the once daily administration. Despite the high systemic safety profile, the chronic use of PGAs may induce periocular and ocular surface (OS)-related side effects, which affect a significant proportion of glaucomatous patients. In this review, we summarize the current knowledge about SEs of PGAs on periocular structures and OS, and their implications in clinical practice...
March 2018: In Vivo
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