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https://www.readbyqxmd.com/read/27906855/periocular-basal-cell-carcinoma-predictors-for-recurrence-and-infiltration-of-the-orbit
#1
Alena Furdova, Pavol Lukacko
PURPOSE: To present the proportion of patients with periocular basal cell carcinoma (BCC) who underwent orbital exenteration and to evaluate the significance of the risk factors. DESIGN: Retrospective, comparative, interventional case series. METHODS: Data of all patients with BCC between 2008 and 2014 were reviewed for patient demographics, previous treatment options, tumor localization, and histopathologic subtype. RESULTS: In group of 256 patients, orbital exenteration underwent 7 patients (2...
November 30, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27898622/review-of-the-treatment-of-periocular-infantile-hemangiomas-with-beta-blockers
#2
Heather M Tamez, Rachel Sobel
No abstract text is available yet for this article.
2017: International Ophthalmology Clinics
https://www.readbyqxmd.com/read/27898621/review-of-targeted-therapies-for-periocular-tumors
#3
Viraj J Mehta, Jeanie Ling, Rachel K Sobel
No abstract text is available yet for this article.
2017: International Ophthalmology Clinics
https://www.readbyqxmd.com/read/27898617/management-of-inflammation-and-periocular-malignancy-in-the-anophthalmic-socket
#4
Caroline W Vargason, Louise A Mawn
No abstract text is available yet for this article.
2017: International Ophthalmology Clinics
https://www.readbyqxmd.com/read/27895515/excellent-response-of-infantile-orbital-hemangioma-to-propranolol
#5
Fandresena A Sendrasoa, Irina M Ranaivo, Naina H Razanakoto, Malalaniaina Andrianarison, Lala S Ramarozatovo, F Rapelanoro Rabenja
Infantile hemangiomas are the most common vascular neoplasm that present in infancy, with more than half affecting the head and neck region. Periocularly, hemangiomas may be complicated by visual loss through induction of strabismal, deprivational, or anisometropic astigmatism. We report a case of a 5-year-old girl who presented with orbital hemangioma with potential risk of visual loss who had excellent response to propranolol.
2016: International Medical Case Reports Journal
https://www.readbyqxmd.com/read/27875090/clinical-computed-tomographic-magnetic-resonance-imaging-and-histologic-findings-associated-with-myxomatous-neoplasia-of-the-temporomandibular-joint-in-two-dogs
#6
Arana Parslow, David P Taylor, David J Simpson
CASE DESCRIPTION A 15-year-old neutered female mixed-breed dog (dog 1) and an 11-year-old neutered female Labrador Retriever (dog 2) were examined because of unilateral exophthalmus, third eyelid protrusion, and periorbital swelling that failed to respond to antimicrobial treatment. CLINICAL FINDINGS Both dogs underwent ultrasonographic, CT, and MRI examination of the head. In both dogs, advanced imaging revealed a poorly defined, peripherally contrast-enhancing, mucous-filled cystic mass that radiated from the temporomandibular joint and infiltrated the periorbital tissues and retrobulbar space...
December 1, 2016: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/27863968/periocular-periorbital-and-orbital-pathology-in-liver-disease
#7
REVIEW
William J Carroll, Travis Peck, Thomas L Jenkins, Zeynel A Karcioglu
Though the connection is not often apparent, hepatic pathology may be associated with ophthalmic disease . We review the literature concerning the periocular, periorbital, and orbital manifestations of various hepatic disorders. This includes periocular/periorbital jaundice, the impact of hepatitis B and C, eyelid changes in cirrhosis, orbital mass lesions in hepatocellular carcinoma, and cutaneous vascular malformations as they are related to liver disease. The motility disorders associated with Wilson's disease, the ophthalmic manifestations of Alagille syndrome, and the effects of liver transplantation are also discussed...
November 15, 2016: Survey of Ophthalmology
https://www.readbyqxmd.com/read/27843644/effect-of-three-dimensional-printed-personalized-moisture-chamber-spectacles-on-the-periocular-humidity
#8
Chan Hee Moon, Jae Yong Kim, Myoung Joon Kim, Hungwon Tchah, Byeong Gak Lim, Jin Kwon Chung
Purpose. To assess the effect of three-dimensional (3D) printed personalized moisture chamber spectacles (PMCS) on the periocular humidity. Methods. Facial computed tomography (CT) scanning was conducted on 10 normal subjects. PMCS was designed based on volume rendered CT images and produced using a 3D printer. Periocular humidity of PMCS and commercially available uniformed moisture chamber spectacles (UMCS) were measured for 30 minutes via microhydrometer. Results. The mean ambient humidity was 15.76 ± 1...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27836332/ocular-pyoderma-gangrenosum-a-systematic-review
#9
Angela S Gupta, Alex G Ortega-Loayza
BACKGROUND: Pyoderma gangrenosum (PG) is a rare, ulcerative cutaneous disorder. Ophthalmic involvement in PG is atypical, but can have devastating consequences. OBJECTIVE: We sought to characterize ocular PG to allow for earlier diagnosis and therapy. To our knowledge, this is the first systematic review summarizing this clinical variant. METHODS: A systematic review was conducted using PubMed and Web of Science. Data were extracted and studies were qualitatively assessed and analyzed...
November 8, 2016: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/27768120/orbital-exenteration-for-advanced-periorbital-non-melanoma-skin-cancer-prognostic-factors-and-survival
#10
R C Gerring, C T Ott, J M Curry, Z B Sargi, S T Wester
PurposeTo describe prognostic factors and survival outcomes in patients who underwent orbital exenteration for periocular non-melanoma cutaneous malignancies.MethodsThe authors performed an institutional review board-approved retrospective review of all patients who underwent orbital exenteration for non-melanoma periocular cutaneous malignancies at a tertiary care hospital system over a 10-year period. Patient demographics, tumor, and treatment data were recorded. Survival outcomes included disease-free survival (DFS) and overall survival (OS)...
October 21, 2016: Eye
https://www.readbyqxmd.com/read/27766598/pharmaceutical-microscale-and-nanoscale-approaches-for-efficient-treatment-of-ocular-diseases
#11
I Bravo-Osuna, V Andrés-Guerrero, P Pastoriza Abal, I T Molina-Martínez, R Herrero-Vanrell
Efficient treatment of ocular diseases can be achieved thanks to the proper use of ophthalmic formulations based on emerging pharmaceutical approaches. Among them, microtechnology and nanotechnology strategies are of great interest in the development of novel drug delivery systems to be used for ocular therapy. The location of the target site in the eye as well as the ophthalmic disease will determine the route of administration (topical, intraocular, periocular, and suprachoroidal administration) and the most adequate device...
October 20, 2016: Drug Delivery and Translational Research
https://www.readbyqxmd.com/read/27752782/-current-diagnostics-and-therapy-recommendations-for-ocular-basal-cell-carcinoma
#12
V Kakkassery, K U Loeffler, M Sand, K R Koch, A M Lentzsch, A C Nick, I A Adamietz, L M Heindl
The treatment options for basal cell carcinoma (BCC) have recently been augmented with the introduction of novel chemotherapeutic drugs. New S2 guidelines on the disease have also been published. The aim of this article is to present a comprehensive state of the art description of the features of ocular BCC and an overview of the various therapeutic options. Particular emphasis is placed on the clinical signs, the diagnostic tools to identify periocular BCC and interpretation of the different histopathological subtypes...
October 17, 2016: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/27749621/periocular-breast-carcinoma-metastases-predominant-origin-from-the-lobular-variant
#13
Frederick A Jakobiec, Anna M Stagner, Natalie Homer, Michael K Yoon
PURPOSE: To further define the histopathologic features of breast carcinoma conducive to orbital metastasis. METHODS: Ten new female patients with orbital or eyelid breast cancer metastases encountered between 2011 and 2016 had their medical records reviewed for determining their clinical characteristics. Microscopic glass slides from biopsies and immunohistochemical test results were also analyzed. Biomarkers studied included cytokeratin 7, nuclear estrogen and progesterone receptors, HER2, and E-cadherin...
October 5, 2016: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/27746645/case-of-pleomorphic-dermal-sarcoma-of-the-eyelid-treated-with-micrographic-surgery-and-secondary-intention-healing
#14
Jung-In Kim, Young-Jun Choi, Hyun-Min Seo, Han-Saem Kim, Jae Yun Lim, Dong-Hoon Kim, Seoung Wan Chae, Ga-Young Lee, Won-Serk Kim
Pleomorphic dermal sarcoma (PDS) is a rare mesenchymal neoplasm sharing histopathological features with atypical fibroxanthoma (AFX), but has additional features of deep invasion of the superficial subcutis, tumor necrosis and vascular/perineural invasion. It is not well documented in the literature because of its rarity, and its clinical course has been debated due to the lack of homogenous criteria. We describe here the case of a 91-year-old female with a 6-month history of a solitary, asymptomatic, well-defined, 3...
October 2016: Annals of Dermatology
https://www.readbyqxmd.com/read/27740698/a-practical-decision-tree-model-to-predict-complexity-of-reconstructive-surgery-after-periocular-basal-cell-carcinoma-excision
#15
E Tan, F Lin, L Sheck, P Salmon, S Ng
PURPOSE: To derive a decision rule for predicting surgical complexity in periorbital basal cell carcinoma (pBCC). DESIGN: Prospective, cohort study. PARTICIPANTS: Patients referred to an oculoplastic service for excision of pBCC from September 2010 to November 2015 METHODS: This study was conducted at two centres in New Zealand from September 2010 to November 2015. Baseline demographic information, and an initial assessment of operative complexity (a four-point grading scale) were collected...
October 14, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27737455/periocular-kaposi-sarcoma-as-the-initial-presentation-of-human-immunodeficiency-virus
#16
Jessica E Weinstein, Katrina A Mears
No abstract text is available yet for this article.
October 13, 2016: JAMA Ophthalmology
https://www.readbyqxmd.com/read/27701636/loss-of-axin2-causes-ocular-defects-during-mouse-eye-development
#17
Ashley Alldredge, Sabine Fuhrmann
Purpose: The scaffold protein Axin2 is an antagonist and universal target of the Wnt/β-catenin pathway. Disruption of Axin2 may lead to developmental eye defects; however, this has not been examined. The purpose of this study was to investigate the role of Axin2 during ocular and extraocular development in mouse. Methods: Animals heterozygous and homozygous for a Axin2lacZ knock-in allele were analyzed at different developmental stages for reporter expression, morphology as well as for the presence of ocular and extraocular markers using histologic and immunohistochemical techniques...
October 1, 2016: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/27697479/primary-orbital-synovial-sarcoma-a-clinicopathologic-review-with-a-differential-diagnosis-and-discussion-of-molecular-genetics
#18
Anna M Stagner, Frederick A Jakobiec, Aaron Fay
Synovial sarcoma (SS) is a soft tissue sarcoma of the extremities developing in young adults that has rarely been reported in the orbit. SS is associated with a unique translocation, resulting in an SYT-SSX fusion gene. We analyze seven published periocular cases, together with the current one, to gain a better appreciation of the features of the tumor in this location and to compare the findings with those derived from non-ophthalmic studies. A 31-year-old woman developed an inferior orbital mass after experiencing periorbital and hemifacial pain for more than a decade...
September 30, 2016: Survey of Ophthalmology
https://www.readbyqxmd.com/read/27671503/the-role-of-personality-in-dyadic-interaction-a-psychophysiological-study
#19
Mikko Salminen, Pentti Henttonen, Niklas Ravaja
Psychophysiological activity was recorded during development discussions of 44 manager-subordinate pairs to examine the effects of the Big Five personality traits Extraversion and Conscientiousness, and personality similarity during dyadic social interaction. Facial electromyography and frontal electroencephalography (EEG) asymmetry were collected continuously during the 30-min discussions. Different actor and partner effects and Actor×Partner interactions were observed. Matching levels of Extraversion led to higher periocular muscle activity, indicating positive valence emotional expressions...
September 24, 2016: International Journal of Psychophysiology
https://www.readbyqxmd.com/read/27661377/master-slave-optical-coherence-tomography-imaging-of-eyelid-basal-cell-carcinoma
#20
Catherine Chin, Adrian Bradu, Rongxuan Lim, Mona Khandwala, John Schofield, Lasse Leick, Adrian Podoleanu
Optical coherence tomography (OCT) is fast emerging as an additional non-interventional modality for skin tumor detection and diagnosis. A master/slave flying spot OCT configuration was assembled to detect periocular basal cell carcinomas (BCC). A swept source at 1300 nm and sweeping speed of 50 kHz were used. A three-step process was involved. First, 384 channeled spectra using a mirror were stored for 384 optical path differences at the master stage. Then, the stored channeled spectra (masks) were correlated with the channeled spectrum from the BCC tissue to produce 384 en face OCT images (200×200 pixels) for the optical path difference values used to acquire the masks...
September 10, 2016: Applied Optics
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