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https://www.readbyqxmd.com/read/29894432/a-predictive-model-for-primary-closure-lengths-in-mohs-surgery-based-on-skin-cancer-type-dimensions-and-location
#1
Zachary A Theroux, Adam B Blechman, Mark A Russell
BACKGROUND: Surgical scar length is a common concern among patients undergoing Mohs micrographic surgery (MMS). OBJECTIVE: This study evaluates 3 metrics of preoperative lesion size to determine which correlates best with primary linear closure lengths for nonmelanoma skin cancers (NMSCs) treated with MMS. This metric is then used to develop predictive models for linear closure lengths in 10 different anatomical regions. MATERIALS AND METHODS: A retrospective study of 4,049 NMSCs treated with MMS and repaired with primary linear closure was conducted...
June 8, 2018: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/29889595/external-beam-radiation-for-localized-periocular-amyloidosis-a-case-series
#2
Thomas S Copperman, Minh Tam Truong, John L Berk, Rachel K Sobel
PURPOSE: To evaluate the effectiveness of low dose external beam radiation therapy to halt progression of localized periocular light chain (AL) amyloidosis, a clonal plasma cell disorder. METHODS: This is a retrospective review of patients referred to a tertiary care center for external beam radiation treatment of biopsy proven localized periocular light chain amyloidosis. The primary outcome measure was clinical disease stability at one year following radiation therapy as evidenced by slit lamp exam and external photography...
June 11, 2018: Orbit
https://www.readbyqxmd.com/read/29882233/periocular-co-2-laser-resurfacing-severe-ocular-complications-from-multiple-unintentional-laser-impacts-on-the-protective-metal-eye-shields
#3
Martin J C van Gemert, Paul R Bloemen, Wei-Yong Wang, Cees W M van der Geld, Rudy M M A Nuijts, Hayri Hortoglu, Albert Wolkerstorfer, Daniel M de Bruin, Ton G van Leeuwen, H A Martino Neumann, Martine J Jager
BACKGROUND AND OBJECTIVES: A 36-year-old woman underwent CO2 laser resurfacing for periocular rhytides using protective stainless steel Cox II ocular shields. Immediately after the treatment, corneal lesions were seen in both eyes. The left eye subsequent developed corneal ulceration and scarring, a deformed iris, cataract, and lower eye lashes showing signs of acute burns. The right cornea had a small inferior mid-peripheral superficial lesion and concomitant lower mid-peripheral burned eye lashes...
June 8, 2018: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/29874471/dog-bite-injuries-of-the-eye-and-ocular-adnexa
#4
Benjamin P Erickson, Paula W Feng, Sophie D Liao, Yasha S Modi, Audrey C Ko, Wendy W Lee
Dog bites result in a diverse range of injuries and complications in the periocular region, particularly in school aged children. It is therefore incumbent on the oculoplastic surgeon to be well versed in both acute and long-term management. The intent of this review is to provide a systematic evaluation of the epidemiology, principles of dog bite wound care, and specific considerations related to common patterns of ophthalmic injury. Review of clinical literature from 1976 to 2014. The majority of periocular injuries result from seemingly benign interactions between young children and familiar dogs...
June 6, 2018: Orbit
https://www.readbyqxmd.com/read/29858421/efficacy-of-phototherapy-to-treat-facial-ageing-when-using-a-red-versus-an-amber-led-a-protocol-for-a-randomised-controlled-trial
#5
Lidiane Rocha Mota, Lara Jansiski Motta, Ivone da Silva Duarte, Anna Carolina Ratto Tempestini Horliana, Daniela de Fátima Teixeira da Silva, Christiane Pavani
INTRODUCTION: The skin undergoes morphological and physiological changes with the advancing age of an individual. These changes may be caused by intrinsic and extrinsic factors that contribute to cellular ageing and consequent skin ageing. The term photoageing is used to characterise the ageing of the skin caused by solar radiation. Clinically, the skin becomes more flaccid, thicker and hyperpigmented, while there is an early appearance of wrinkles and other skin changes, such as skin cancer...
May 31, 2018: BMJ Open
https://www.readbyqxmd.com/read/29846420/undifferentiated-pleomorphic-sarcoma-of-the-orbital-region-a-case-report
#6
Natasha Ferreira Santos da Cruz, Carolina Ando Matsuno, Sérgio Ferreira Santos da Cruz, Aline Pimentel de Miranda, José Vital Filho
Undifferentiated pleomorphic sarcoma (UPS) is an extremely rare tumor that occurs in the head and neck region. Here, we report a unique case of a primary undifferentiated pleomorphic sarcoma in the orbital region. A 35-year-old woman presented with a progressive proptosis and periocular edema for 1 year. She had no previous history of surgery, skin malignancy, or radiation. Imaging tests showed an extraconal mass, not involving the muscles. The tumor was surgically removed and adjuvant radiotherapy was required after histological examination, which showed an undifferentiated pleomorphic sarcoma of the orbit...
April 2018: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/29785086/the-utilization-of-an-ocular-wound-chamber-on-corneal-epithelial-wounds
#7
Jennifer S McDaniel, Andrew W Holt, Elaine D Por, Elof Eriksson, Anthony J Johnson, Gina L Griffith
Purpose: Currently available ocular moisture chambers are not adequate to manage the treatment of periocular burns, corneal injuries, and infection. The purpose of these studies was to demonstrate that a flexible, semi-transparent ocular wound chamber device adapted from technology currently used on dermal wounds is safe for use on corneal epithelial injuries. Materials and methods: A depilatory cream (Nair™, 30 seconds) was utilized to remove the excess hair surrounding the left eyes of anesthetized Institute Armand Frappier (IAF) hairless, female guinea pigs (Crl:HA-Hrhr)...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29778494/povidone-iodine-concentration-and-dosing-in-cataract-surgery
#8
REVIEW
Jagger C Koerner, Mary J George, Dale R Meyer, Michael G Rosco, Matthew M Habib
Iodine has been recognized as an effective bactericide since the 1800's, and povidone-iodine (PI) solution has been applied to the ocular surface and periocular skin since the 1980's to prevent endophthalmitis in cataract surgery. In vitro, PI solution kills bacteria very quickly at dilute concentrations (0.05-1.0%). In many instances, PI kills bacteria more quickly at these dilute concentrations than more conventional (5%-10%) concentrations. This is due to greater availability of diatomic free iodine in dilute solution, the bactericidal component of PI...
May 17, 2018: Survey of Ophthalmology
https://www.readbyqxmd.com/read/29777299/-advanced-periocular-basal-cell-carcinoma-a-therapeutic-challenge
#9
B Lauterbach, V Kakkassery, D Debus, L M Heindl, E S Schultz
BACKGROUND: Basal cell carcinomas are the most common periocular malignant tumor. In advanced periocular basal cell carcinoma, vismodegib is a new treatment option which might potentially avoid surgical eye removal. CASE REPORT: We treated a 76-year-old patient unwilling to consent to surgery with vismodegib for advanced periocular basal cell carcinoma on the left forehead that had already undergone several previous treatments. After initial partial remission, the tumor regrew under ongoing therapy, so that radical surgical excision including orbital exenteration was performed...
May 17, 2018: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/29774642/micropunch-blepharopeeling-versus-blepharoplasty-what-is-the-best-procedure-for-upper-eyelid-rejuvenation
#10
Ali Asilian, Behzad Bafandeh, Zabihollah Shahmoradi, Gita Faghihi, Anis Bostakian, Samaneh Mozafarpoor, Sayed Mohsen Hosseini
INTRODUCTION: Periocular rejuvenation is the most common aesthetic plastic surgery. The aim of this study was to determine effects of micropunch blepharopeeling (MBP) approach vs blepharoplasty (BP) in periocular rejuvenation. METHODS AND MATERIALS: This is a clinical trial study on 22 patients who underwent periorbital rejuvenation referred to University Skin Clinics. Patients were randomly divided into two groups of blepharoplasty or micropunch blepharopeeling...
May 17, 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29771754/orbital-decompression-for-thyroid-related-orbitopathy-during-the-quiescent-phase
#11
Lilangi S Ediriwickrema, Bobby S Korn, Don O Kikkawa
PURPOSE: To describe historical and modern surgical approaches to orbital decompression in patients with thyroid-related orbitopathy in the quiescent phase. METHODS: A literature review of published techniques using the National Institutes of Health PubMed database. RESULTS: Historically, orbital decompression has been accomplished via transantral, transcranial, transnasal, and orbital approaches. Current techniques use predominately periocular incisions to achieve effective decompression and proptosis reduction...
May 2, 2018: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29766626/co-2-laser-and-photodynamic-therapy-study-of-efficacy-in-periocular-bcc
#12
Santo Raffaele Mercuri, Pina Brianti, Annunziata Dattola, Luigi Bennardo, Martina Silvestri, Giusy Schipani, Steven Paul Nisticò
Basal cell carcinoma (BCC), the most common type of skin cancer in the world, usually arises in sun-exposed areas of the skin. The therapeutic approach to periocular BCC has changed in the last few years. Currently the treatment, considering the delicate localization of the disease, must not only ensure complete recovery from the neoplastic disease, but must also satisfy functional and aesthetic criteria. In this study we tried to evaluate the efficacy of CO2 laser and photodynamic therapy in periocular BCC...
May 15, 2018: Dermatologic Therapy
https://www.readbyqxmd.com/read/29766557/risk-factors-for-ocular-complications-in-periocular-infantile-hemangiomas
#13
Liat Samuelov, Michael Kinori, Karen Rychlik, Meghana Konanur, Sarah L Chamlin, Bahram Rahmani, Anthony J Mancini
BACKGROUND/OBJECTIVES: Infantile hemangiomas are the most common benign tumors of childhood. Although some children with periocular infantile hemangiomas do not require treatment, these lesions may result in amblyopia and visual impairment if not properly treated. We have attempted to characterize clinical features of periocular infantile hemangiomas that predict negative ocular outcomes and thus require prompt referral to an ophthalmologist and initiation of therapy. METHODS: This study included children with periocular infantile hemangiomas consecutively seen at Ann & Robert H...
May 15, 2018: Pediatric Dermatology
https://www.readbyqxmd.com/read/29765274/review-of-eyelid-reconstruction-techniques-after-mohs-surgery
#14
REVIEW
Sagar Yatin Patel, Kamel Itani
Mohs micrographic surgery achieves high cure rates while preserving healthy tissue making it the optimal treatment for skin cancer. The goals of eyelid reconstruction after Mohs surgery include restoring eyelid structure and function while attaining acceptable aesthetic results. Given the variety of eyelid defects encountered after Mohs surgery, a thorough understanding of the complex eyelid anatomy as well as an in-depth knowledge of the numerous reconstructive techniques available are required to accomplish these reconstructive goals...
May 2018: Seminars in Plastic Surgery
https://www.readbyqxmd.com/read/29762893/retrobulbar-vs-peribulbar-regional-anesthesia-techniques-using-bupivacaine-in-dogs
#15
Yael Shilo-Benjamini, Peter J Pascoe, David J Maggs, Steven R Hollingsworth, Ann R Strom, Kathryn L Good, Sara M Thomasy, Philip H Kass, Erik R Wisner
OBJECTIVE: To compare the effectiveness of retrobulbar anesthesia (RBA) and peribulbar anesthesia (PBA) in dogs. ANIMAL STUDIED: Six adult mixed-breed dogs (18-24 kg). PROCEDURES: In a randomized, masked, crossover trial with a 10-day washout period, each dog was sedated with intravenously administered dexmedetomidine and administered 0.5% bupivacaine:iopamidol (4:1) as RBA (2 mL via a ventrolateral site) or PBA (5 mL divided equally between ventrolateral and dorsomedial sites)...
May 15, 2018: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/29760516/microrna-and-transcriptome-analysis-in-periocular-sebaceous-gland-carcinoma
#16
John C Bladen, Jun Wang, Ajanthah Sangaralingam, Mariya Moosajee, Caroline Fitchett, Claude Chelala, Michele Beaconsfield, Edel A O'Toole, Michael P Philpott, Daniel G Ezra
Sebaceous gland carcinoma (SGC) is a rare, but life-threatening condition with a predilection for the periocular region. Eyelid SGC can be broadly categorised into two subtypes, namely either nodular or pagetoid with the latter being more aggressive and requiring radical excision to save life. We have identified key altered microRNAs (miRNA) involved in SGC shared by both subtypes, hsa-miR-34a-5p and hsa-miR-16-5p. However, their gene targets BCL2 and MYC were differentially expressed with both overexpressed in pagetoid but unchanged in nodular suggesting different modes of action of these two miRNAs on BCL/MYC expression...
May 14, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29755269/inflammatory-myofibroblastic-tumor-of-the-orbit-a-clinico-pathological-study-of-25-cases
#17
Diego Strianese, Fausto Tranfa, Marialuisa Finelli, Adriana Iuliano, Stefania Staibano, Giuseppe Mariniello
Background: Inflammatory myofibroblastic tumor (IMT) is a rare entity characterized by the presence of myofibroblasts and inflammatory cells within a fibrous stroma, which typically occurs in children or young adults. The IMT is considered generally a benign lesion, although about 20% of cases may experience recurrence, and most rarely develop metastasis. Herein, we present the largest series of primary orbital IMT ever reported. Patients and methods: The clinical records of 25 patients, collected between the 1995 and 2015, with biopsy-proven diagnosis of orbital IMT were retrospectively reviewed to determine demographic, clinical, radiologic and pathological features, management, and outcome...
January 2018: Saudi Journal of Ophthalmology: Official Journal of the Saudi Ophthalmological Society
https://www.readbyqxmd.com/read/29744034/new-advances-in-understanding-thyroid-associated-ophthalmopathy-and-the-potential-role-for-insulin-like-growth-factor-i-receptor
#18
REVIEW
Terry J Smith
Thyroid-associated ophthalmopathy (TAO), a localized periocular manifestation of the autoimmune syndrome known as Graves' disease, remains incompletely understood. Discussions of its pathogenesis are generally focused on the thyrotropin receptor, the proposed role for which is supported by substantial evidence. Considerations of any involvement of the insulin-like growth factor-I receptor (IGF-IR) in the disease are frequently contentious. In this brief, topically focused review, I have attempted to provide a balanced perspective based entirely on experimental results that either favor or refute involvement of IGF-IR in TAO...
2018: F1000Research
https://www.readbyqxmd.com/read/29738013/atypical-posterior-scleritis-mimicking-choroidal-melanoma
#19
Heba M Alsharif, Saad A Al-Dahmash
We report a case of atypical posterior scleritis mimicking amelanotic choroidal melanoma. A 30-year-old healthy Filipino man, with a history of painless subacute loss of vision in his left eye over 5 months, was referred to our institute for further workup and management. On examination, visual acuity of the left eye was 20/200. Anterior segment examination yielded unremarkable results, with injected conjunctiva and quiet episcleral blood vessels, while fundus examination revealed non-pigmented nasal choroidal mass, with significant subretinal fluid resembling amelanotic choroidal melanoma...
May 2018: Saudi Medical Journal
https://www.readbyqxmd.com/read/29719649/a-case-of-post-encephalitic-optic-neuritis-clinical-spectrum-differential-diagnosis-and-management
#20
Ravinder Kumar, Abhishek Bhargava, Gagan Jaiswal, Viral R Soni, Bhoomika Katbamna, Arpit Vashisht
Purpose: Most cases of optic neuritis are idiopathic or are associated with multiple sclerosis. We present a case in which a young female developed post-infectious left optic neuritis following herpes simplex encephalitis (HSE). Case Report: A 24-year-old female presented with a severe headache, fever, and malaise of a one-week duration. Viral encephalitis was diagnosed and treated; intravenous acyclovir (750 mg every 8 h) was administered for 14 days. The patient improved clinically and was prescribed oral valacyclovir (1,000 mg, three times daily) for an additional 3 months as an outpatient...
April 2018: Journal of Ophthalmic & Vision Research
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