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I A Filatova
By improving the existing surgical technologies for dacryocystitis, one enhances the effectiveness of patient rehabilitation. AIM: To evaluate the effectiveness of radio-wave surgery in the treatment of dacryocystitis and lacrimal sac abscesses. MATERIAL AND METHODS: The clinical group consisted of 207 patients ranging in age from 7 to 89 years (the mean age of 41±7.3 years). For 39% of patients this was a repeated treatment, while 9.3% had undergone 4-5 surgical interventions...
2018: Vestnik Oftalmologii
T N Safonova, N P Kintiukhina
PURPOSE: to identify the role of laser scanning confocal microscopy (LSCM) in diagnostic and to assess the effectiveness of involutional blepharitis treatment. MATERIAL AND METHODS: The study involved 32 patients (64 eyes) with chronic blepharitis aged in average 75.21±3.56 years. All patients completed questionnaire (SPEED), underwent Schirmer I, Norn tear break-up time and compression tests, had the number of functioning meibomian glands (NFMG) calculated. The patients' eyelids were examined with LSCM, and the condition of conjunctiva was evaluated by microbiological study...
2018: Vestnik Oftalmologii
Seda Ekizoglu, Turgut Ulutin, Jalal Guliyev, Nur Buyru
Head and neck squamous cell carcinomas (HNSCC) are a diverse group of tumor types, including neoplasia of the paranasal sinuses, oral cavity, trachea, pharynx and larynx. Laryngeal cancer is the most common type of HNSCC. The proline-rich 4 (PRR4) protein is synthesized in the acinar cells of human lacrimal glands. Previous studies have demonstrated that PRR4 may function as an antimicrobial protein protecting the ocular surface and the oral cavity. In order to determine differentially expressed genes (DEGs) in laryngeal tumors, a GeneFishing Assay was performed; 27 DEGs were identified...
April 2018: Oncology Letters
Ayse Ipek Akyuz Unsal, Yesim Basal, Serap Birincioglu, Tolga Kocaturk, Harun Cakmak, Alparslan Unsal, Gizem Cakiroz, Nüket Eliyatkın, Ozden Yukselen, Buket Demirci
PURPOSE: To investigate the potential effects of chronic exposure to a nasal decongestant and its excipients on ocular tissues using an experimental rat model. METHODS: Sixty adult male Wistar rats were randomized into six groups. The first two groups were control (serum physiologic) and Otrivine® groups. The remaining four groups received the Otrivine excipients xylometazoline, benzalkonium chloride, sorbitol, and ethylene diamine tetra acetic acid. Medications were applied into both nostrils twice a day for 8 weeks...
January 2018: Arquivos Brasileiros de Oftalmologia
Nicholas H Andrew, Dinesh Selva, Alan A McNab
No abstract text is available yet for this article.
March 12, 2018: Orbit
(no author information available yet)
No abstract text is available yet for this article.
March 12, 2018: Orbit
Michelle L Ratay, Stephen C Balmert, Ethan J Bassin, Steven R Little
Dry eye disease (DED), also known as keratoconjunctivitis sicca, is an ocular surface disease characterized by T-cell-mediated inflammation. Current therapeutics, such as immunosuppressive agents, act to suppress the clinical signs and inflammation. However, long-term usage of these treatments can cause severe side effects. In this study, we present an alternative therapeutic approach that utilizes a histone deacetylase inhibitor (HDACi) to regulate transcription of a variety of immunomodulatory genes. Specifically, HDACi have emerged as a potential anti-inflammatory agent, which can modulate the functions of a subset of suppressive T lymphocytes known as regulatory T cells (Tregs), enhancing FoxP3 acetylation and subsequently guarding the transcription factor from proteasomal degradation...
March 8, 2018: Acta Biomaterialia
Declan C Murphy, Mohamed Alfiky, Peter Prinsley
Oncocytomas are rare glandular tumours, typically found in salivary glands and kidneys. A 76-year-old man presented to an ophthalmology department after 3 months of persistent right-sided epiphora. Lacrimal syringing and a fluorescein dye test demonstrated an obstruction at the level of the nasolacrimal duct (NLD). Owing to the patient's history of dacryocystitis, endoscopic dacryocystorhinostomy was organised. When in theatre however, nasendoscopy identified a polypoid mass at the lateral aspect of the inferior turbinate, obstructing the right NLD opening...
March 9, 2018: BMJ Case Reports
Thomas J W Klein Nulent, Matthijs H Valstar, Bart de Keizer, Stefan M Willems, Laura A Smit, Abrahim Al-Mamgani, Ludwig E Smeele, Robert J J van Es, Remco de Bree, Wouter V Vogel
OBJECTIVES: Prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT) is used for detection and (re)staging of prostate cancer. However, healthy salivary, seromucous, and lacrimal glands also have high PSMA-ligand uptake. This study aimed to describe physiologic PSMA-ligand uptake distribution characteristics in the head and neck to aid in PSMA PET/CT interpretation and to identify possible new clinical applications for PSMA-ligand imaging. STUDY DESIGN: Thirty consecutive patients who underwent PSMA PET/CT for prostate cancer were evaluated...
January 31, 2018: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Tyler Hyungtaek Rim, JaeSang Ko, Sung Soo Kim, Jin Sook Yoon
GOALS: This study aimed to evaluate the association between gastroesophageal reflux disease (GERD) and development of lacrimal drainage obstruction (LDO). BACKGROUND: It has been hypothesized that GERD may contribute toward the development of LDO. STUDY: This was a retrospective study of Koreans aged 40 to 79 years registered in the Korean National Health Screening Cohort from 2002 to 2013. Incident cases of LDO were identified according to the Korean Classification of Disease...
March 7, 2018: Journal of Clinical Gastroenterology
J R Si, Y L Zhang
Objective: To investigate the static and dynamic features of the normal lacrimal sac (LS)-nasolacrimal duct (NLD), and find out if tear flows while the subject is in supine position with eyes closed. Methods: Cross-sectional study. Healthy volunteers and patients whose head were examined by MRI in Guangdong Provincial Hospital of Integrated Traditional Chinese and Western Medicine with normal LS-NLD were recruited. The normal lacrimal ducts of the candidates were scanned, while candidates remained in supine position, by static or dynamic imaging procedures with a 1...
March 11, 2018: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
Franck Fajnkuchen, Denis Barritault, Audrey Giocanti-Aurégan
RATIONALE: Sjögren syndrome (SS) is frequently associated with ulcerative keratitis, which is difficult to treat due to lacrimal tear deficiency and inflammation of the ocular surface. PATIENT CONCERNS: We report the successful additive effect of a matrix regenerating agent (RGTA, Cacicol) in SS patients with severe superficial ulcerative keratitis resistant to conventional therapy. DIAGNOSES: Retrospective, noncomparative case series of patients with primary or secondary SS associated with chronic diffuse keratitis...
March 2018: Medicine (Baltimore)
Alan D Proia, Roshni Ranjit-Reeves, Julie A Woodward
No abstract text is available yet for this article.
2018: International Ophthalmology Clinics
Sarina K Mueller, Suzanne K Freitag, Daniel R Lefebvre, Nahyoung G Lee, Benjamin S Bleier
BACKGROUND: Endoscopic dacryocystorhinostomies (eDCRs) show patency rates between 81% and 94%. However, dacryocystorhinostomy (DCR) failure and the need for revision remain a significant challenge. One of the principal challenges in revision eDCR is the need to surgically identify the correct osteotomy site and maintain long-term patency in the setting of previously instrumented and potentially scarred tissue. At the same time, the surgeon must assume that the blood supply to the commonly described anterior and posteriorly pedicled flaps has been compromised...
March 8, 2018: Orbit
Cristina Nicula, Izabela Szabo, Ozana Ivan
The article presents the modern treatment with stem cells in the reconstruction of ocular surface. The turnover of the stem cells, the location in the limbus areas, the importance of limbal stem cells presence, the clinical appearance of stem cell deficiency, investigations method for this illness and the management of stem cell deficiency (artificial lacrimal tear drops, mini scleral contact lenses and the surgical treatment with allografts and autografts of stem cells) were taken into account.
October 2017: Romanian Journal of Ophthalmology
Veronica Ferrero, Elisa Fiorina, Matteo Morrocchi, Francesco Pennazio, Guido Baroni, Giuseppe Battistoni, Nicola Belcari, Niccolo' Camarlinghi, Mario Ciocca, Alberto Del Guerra, Marco Donetti, Simona Giordanengo, Giuseppe Giraudo, Vincenzo Patera, Cristiana Peroni, Angelo Rivetti, Manuel Dionisio da Rocha Rolo, Sandro Rossi, Valeria Rosso, Giancarlo Sportelli, Sara Tampellini, Francesca Valvo, Richard Wheadon, Piergiorgio Cerello, Maria Giuseppina Bisogni
Particle therapy exploits the energy deposition pattern of hadron beams. The narrow Bragg Peak at the end of range is a major advantage but range uncertainties can cause severe damage and require online verification to maximise the effectiveness in clinics. In-beam Positron Emission Tomography (PET) is a non-invasive, promising in-vivo technique, which consists in the measurement of the β+ activity induced by beam-tissue interactions during treatment, and presents the highest correlation of the measured activity distribution with the deposited dose, since it is not much influenced by biological washout...
March 6, 2018: Scientific Reports
Ulrik Nikolaj Ascanius Felding
Isolated fractures of the orbital floor or medial wall are often referred to as blowout fractures (BOFs). Debilitating double vision and aesthetic deformity may affect the patients' quality of life and daily living skills, for instance, working or driving a car. The management of blowout fractures is, however, challenging, since not all fractures demand surgery. Some patients may have symptoms which subside, or may never develop symptoms. Due to a lack of evidence, there are still considerable differences in opinion on the criteria for surgery...
March 2018: Danish Medical Journal
E D Feijo, R M Limongi, S Matayoshi
BACKGROUND: Dacryocystorhinostomy (DCR) is the gold standard surgical treatment for nasolacrimal duct obstruction. External DCR is the traditional approach (EXT-DCR); however, the advent of minimally invasive surgeries and the development of optic fiber and laser technologies have made it possible to perform laser transcanalicular DCR (T-DCR), a minimally invasive procedure. This study measured the fluorescein transit time (FTT) after EXT-DCR or T-DCR to evaluate the lacrimal drainage and lacrimal pump function after these two types of DCR...
March 6, 2018: Rhinology
Kun Hwang, Xia Jing Wu, Hun Kim, Dae Joong Kim
The aim of this study was to elucidate the sensory territory of the trigeminal nerve on the upper eyelid.Eight hemifaces from Korean cadavers were dissected. The frontal nerve (FN), supraorbital nerve (SON), supratrochlear nerve (STN), infratrochlear nerve (ITN), and lacrimal nerve (LN) were traced.The terminal branches to the eyelid margin of FN were distributed between 1/6 and 2/5 of the palpebral fissure width lateral to the medial canthus and 1/6 of the eyebrow height from eyelid margin. The SON was distributed between 2/5 and 9/10 of the eye width lateral to the medial canthus, at 1/3 of the eyebrow height...
March 2018: Journal of Craniofacial Surgery
Jacek Kuchinka
The persistent stapedial artery is a component of the main arterial roads of the head in some animal groups (Frąckowiak 2003). This type of vascularization occurs in the Mongolian gerbil, among others. The stapedial artery is common in a variety of forms in rodents. It has been described, for example, in Sciuridae, Muridae, Heteromyidae, Geomyidae, Splacidae, Cricetidae, Arvicolinae, and in genus Jaculus (Cox and Hautier, 2015). The aim of this study was the analysis of morphology, and of course, of the stapedial artery in this species...
March 5, 2018: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
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