Jin Liu, Haoze Wu, Jun Qiu, Sirui Yang, Doudou Xiang, Xinhua Zhang, Jinxin Kuang, Min Xiao, Qing Yu, Xiaogang Cheng
AIM: The current study evaluated the antibacterial activity of a newly developed quaternary ammonium polymethacrylate (QAPM)-containing bioactive glasses (BGs) via a two-step method by our group, namely BGs-HAEMB, and explored its cytotoxicity and biocompatibility. METHODS: The antibacterial effects of the BGs-HAEMB against planktonic bacteria, bacterial biofilm formation, and experimental root canal biofilms of persistent pathogens ( Enterococcus faecalis , Streptococcus sanguis and Porphyromonas endodontalis ) associated with endodontic infection were evaluated in vitro by agar diffusion tests, direct contact tests and live/dead staining...
April 15, 2024: Heliyon