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https://www.readbyqxmd.com/read/29034562/canine-central-corneal-thickness-measurements-via-pentacam-hr-%C3%A2-optical-coherence-tomography-optovue-ivue-%C3%A2-and-high-resolution-ultrasound-biomicroscopy
#1
Allison E Wolfel, Samantha L Pederson, Allison M Cleymaet, Ann M Hess, Kate S Freeman
OBJECTIVE: To compare central corneal thickness (CCT) values in canine eyes using Pentacam-HR(®) Scheimpflug imaging (Pentacam), Optovue(®) iVue spectral-domain optical coherence tomography (SD-OCT), and high-resolution ultrasound biomicroscopy (UBM) and generate normative canine Pentacam CCT values. ANIMALS STUDIED: Twenty-four client-owned dogs (37 eyes) with nondiseased cornea(s) presenting to the Colorado State University Veterinary Teaching Hospital. PROCEDURES: Corneal images were acquired via Pentacam, SD-OCT, and UBM in the listed order...
October 15, 2017: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/29034411/impact-of-corneal-donor-lens-status-on-two-year-course-and-outcome-of-descemet-membrane-endothelial-keratoplasty-dmek
#2
Friederike Schaub, Layla Pohl, Philip Enders, Werner Adler, Björn O Bachmann, Claus Cursiefen, Ludwig M Heindl
PURPOSE: Our purpose was to investigate the impact of lens status of corneal donors on the two-year course and clinical outcome of Descemet membrane endothelial keratoplasty (DMEK). METHODS: In 181 DMEK surgeries, 136 phakic and 45 pseudophakic donor corneas were grafted. In this retrospective audit we compared the lens status of corneal donors regarding the outcome measures best spectacle-corrected visual acuity (BSCVA), central corneal thickness (CCT), and endothelial cell density (ECD) at 1, 3, 6, 12, and 24 months, as well as intra- and postoperative complication rates and graft detachment rates requiring re-bubbling...
October 15, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29034156/intraocular-lens-opacification-after-descemet-s-stripping-automated-endothelial-keratoplasty
#3
Meng-Sheng Lee, I-Lun Tsai, Ching-Yao Tsai, Li-Lin Kuo, Shiow-Wen Liou, Lin-Chung Woung
Compared with conventional penetrating keratoplasty, Descemet's stripping automated endothelial keratoplasty (DSAEK) more effectively maintain global integrity and rapid vision rehabilitation with less ocular surface disorders in patients with endothelial dysfunction. Here, we report a case of a 76-year-old woman who experienced opacification of a hydrophilic intraocular lens (IOL) approximately 10 months after DSAEK. The patient with no history of systemic disease developed pseudophakic bullous keratopathy in the right eye 2 years after undergoing cataract surgery...
July 2017: Taiwan Journal of Ophthalmology
https://www.readbyqxmd.com/read/29034154/intraocular-pressure-monitoring-by-rebound-tonometry-in-children-with-myopia
#4
Jenchieh Weng, I-Lun Tsai, Li-Lin Kuo, Ching-Yao Tsai, Lin-Chung Woung, Ya-Chuan Hsiao
BACKGROUND/PURPOSE: Topical atropine treatment is generally accepted to retard the progression of myopia, but it is associated with side effects such as photophobia and elevation of intraocular pressure (IOP). IOP measurements in children are challenging. The traditional applanation tonometry by direct contact with the cornea will require patient's cooperation. The rebound tonometer, using a dynamic electromechanical method for measuring IOP, shows good correlation with traditional tonometry...
July 2017: Taiwan Journal of Ophthalmology
https://www.readbyqxmd.com/read/29032414/influence-of-lasek-on-schi%C3%A3-tz-goldmann-and-dynamic-contour-tonometry
#5
Marco Sales-Sanz, Esther Arranz-Marquez, Carolina Arruabarrena, Miguel A Teus
PURPOSE: Our purpose was to assess the effect of LASEK surgery on ocular rigidity and to compare its effect on intraocular pressure (IOP) readings with Goldmann applanation tonometry (GAT), Schiøtz indentation tonometry (ST) and dynamic contour tonometry (DCT). METHODS: Prospective, observational, single-masked cohort study. One eye per patient from 31 consecutive subjects who underwent LASEK refractive surgery to correct myopia, as well as from 108 non-operated myopic patients, were included...
October 14, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29032336/a-mouse-dry-eye-model-induced-by-topical-administration-of-the-air-pollutant-particulate-matter-10
#6
Juan Li, Gang Tan, Xiaoyan Ding, Yahong Wang, Anhua Wu, Qichen Yang, Lei Ye, Yi Shao
AIM: To introduce a novel dry eye mouse model induced by topical administration of the air pollutant particulate matter 10 (PM10). METHOD: A total of 60 male BALB/c mice were used in this study and divided into two groups: group A (PBS eye drops, n=30) and group B (PM10 eye drop group, n=30). Each treatment was dosed four times a day, every time 50ul with the concentration of 5mg/ml PM10, for 14 consecutive days in the right eye. The clinical manifestations of dry eye were measured before therapy and 4, 7 and 14days post-treatment respectively, which included the tear volume, tear break-up (BUT) time, corneal fluorescein staining, rose bengal staining, Lissamine Green staining and inflammatory index...
October 12, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29032108/pregnancy-induced-changes-in-corneal-biomechanics-and-topography-are-thyroid-hormone-related
#7
David Tabibian, Begoña M de Tejada, Zisis Gatzioufas, Sabine Kling, Vanessa S Meiss, Marc-Olivier Boldi, Véronique Othenin-Girard, Antonina Chilin, Julien Lambiel, Florence Hoogewoud, Farhad Hafezi
PURPOSE: To identify biomechanical and topographical changes of the cornea during pregnancy and the postpartum period and its association to hormonal changes. DESIGN: Prospective single-center observational cohort study. METHODS: Participants: 24 pregnant women (48 eyes), monitored throughout pregnancy and after delivery. Biomechanical and topographical corneal properties were measured using the Ocular Response Analyzer (ORA) and a Scheimpflug imaging system (Pentacam HR) each trimester and 1 month after delivery...
October 12, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29030797/corneal-endothelial-changes-following-a-single-session-of-selective-laser-trabeculoplasty-for-pseudoexfoliative-glaucoma
#8
Nurgül Örnek, Kemal Örnek
PURPOSE: To evaluate corneal endothelial cell parameters after a single session of selective laser trabeculoplasty (SLT) in pseudoexfoliative glaucoma (PEG) patients. METHODS: Corneal endothelial cell parameters of 18 PEG patients were compared with 18 healthy subjects following SLT treatment. All patients underwent SLT treatment to 180 degrees of inferior trabecular meshwork. Corneal measurements were performed using specular microscopy (Noncon Robo SP8000, Konan Medical, Hyogo, Japan)...
October 13, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/29030589/aberrant-ocular-architecture-and-function-in-patients-with-klinefelter-syndrome
#9
Cristin Brand, Michael Zitzmann, Nicole Eter, Sabine Kliesch, Joachim Wistuba, Maged Alnawaiseh, Peter Heiduschka
Klinefelter Syndrome (KS), the most common chromosomal disorder in men (47,XXY), is associated with numerous comorbidities. Based on a number of isolated case reports, we performed the first systematic and comprehensive evaluation of eye health in KS patients with a focus on ocular structure and vascularization. Twenty-one KS patients and 26 male and 38 female controls underwent a variety of non-invasive examinations investigating ocular morphology (examination of retinal thickness, optic nerve head, and cornea) and function (visual field testing and quantification of ocular vessel density by optical coherence tomography angiography)...
October 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29030535/reply-to-herpes-simplex-virus-1-macrophages-and-the-cornea
#10
Dhong Hyun Lee, Homayon Ghiasi
No abstract text is available yet for this article.
November 1, 2017: Journal of Virology
https://www.readbyqxmd.com/read/29030302/mesenchymal-stem-cell-therapy-for-retro-corneal-membrane-a-clinical-challenge-in-full-thickness-transplantation-of-biosynthetic-corneal-equivalents
#11
Vijayalakshmi Rajendran, Magdalena Netuková, May Griffith, John V Forrester, Lucia Kuffová
Artificial corneas (keratoprostheses) and biosynthetic collagen-based corneal equivalents are surgical implants designed to ease the global burden of corneal blindness. However, keratoprostheses in many cases fail due to development of fibrous retro-corneal membranes (RCM). Fibrous membranes which develop in the anterior chamber after prosthesis implantation do so on a matrix of fibrin. This study investigated fibrin deposition and RCM formation after full-thickness collagen-based hydrogel implants and compared them with syngeneic and allogeneic corneal grafts in mice...
October 10, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/29030016/does-a-two-year-period-of-orthokeratology-lead-to-changes-in-the-endothelial-morphology-of-children
#12
Sin Wan Cheung, Pauline Cho
PURPOSE: To compare changes in endothelial morphology in the central and superior cornea in subjects wearing single-vision spectacles and orthokeratology lenses over two years. METHODS: Endothelial images of the two locations of 99 subjects (6-12 years) from completed myopia control studies were analysed. Endothelial cell density (ECD), coefficient of variation in cell size (CV), and hexagonality (HEX) before and two years after treatment were compared between the two groups of subjects...
October 10, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/29028106/correlation-between-presence-of-primary-iris-and-cilliary-body-cysts-and-intraocular-pressure
#13
K-C Xue, D-D Hu, L Zhao, N Li, H-Y Shen
OBJECTIVE: The objective of this study was to examine the correlation between the presence of primary iris-ciliary cysts and the intraocular pressure. PATIENTS AND METHODS: Sixty patients with short-sightedness undergoing routine examination for laser vision correction in our hospital in 2003 were enrolled. Patients with known high intraocular pressure and risk of glaucoma were excluded from the study. A total of 119 eyes were examined by the Ultrasound Biomicroscope (UBM), and the presence of the primary iris-ciliary cysts was confirmed...
September 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29027064/light-scattering-measurements-in-electron-beam-sterilized-corneas-stored-in-recombinant-human-serum-albumin
#14
Khoa D Tran, Yan Li, Jeffrey D Holiman, Maolong Tang, David Huang, Michael D Straiko, Christopher G Stoeger
Irradiated corneal tissues have been used for a variety of ophthalmic procedures including glaucoma drainage device covers and lamellar grafts. The maintenance of corneal clarity is important, as light obstructions resulting from processing or long-term storage of irradiated corneas may negatively affect vision and postoperative cosmesis. It has been reported that corneal tissues can be preserved in human serum albumin (HSA), however, the clarity of corneas after long-term storage in HSA has not been well described...
October 12, 2017: Cell and Tissue Banking
https://www.readbyqxmd.com/read/29024692/the-role-of-hepatocyte-growth-factor-in-corneal-wound-healing
#15
REVIEW
Hidetaka Miyagi, Sara M Thomasy, Paul Russell, Christopher J Murphy
Hepatocyte growth factor (HGF) is a glycoprotein produced by mesenchymal cells and operates as a key molecule for tissue generation and renewal. During corneal injury, HGF is primarily secreted by stromal fibroblasts and promotes epithelial wound healing in a paracrine manner. While this mesenchymal-epithelial interaction is well characterized in various organs and the cornea, the role of HGF in corneal stromal and endothelial wound healing is understudied. In addition, HGF has been shown to play an anti-fibrotic role by inhibiting myofibroblast generation and subsequent production of a disorganized extracellular matrix and tissue fibrosis...
October 9, 2017: Experimental Eye Research
https://www.readbyqxmd.com/read/29024376/evaluation-of-collagen-foam-poly-l-lactic-acid-nanofiber-mesh-and-decellularized-matrices-for-corneal-regeneration
#16
Bahar Aslan, Selcan Guler, Atakan Tevlek, Halil Murat Aydin
Corneal tissue engineering efforts to obtain corneal tissue matrices through various types of materials for the replacement of damaged tissues. In this study, three different corneal constructs were prepared and evaluated in terms of morphological, optical, and biological characteristics. Type-I collagen was used to obtain collagen foam scaffolds through dehydrothermal crosslinking, while poly(l-lactic acid) (PLLA) was used to produce both random and aligned oriented electrospun corneal constructs. Bovine corneas were decellularized as third matrix...
October 12, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/29023521/factors-affecting-eye-drop-instillation-in-glaucoma-patients-with-visual-field-defect
#17
Tomoko Naito, Koji Namiguchi, Keiji Yoshikawa, Kazuhisa Miyamoto, Shiro Mizoue, Yoichi Kawashima, Atushi Shiraishi, Fumio Shiraga
BACKGROUND: To investigate the success rate of eye drop instillation in glaucoma patients with visual field defect as well as non-glaucoma volunteers. Factors that may affect the success rate of eye drop instillation were also evaluated. DESIGN: A prospective, observational study. PARTICIPANTS: Seventy-eight glaucoma patients and 85 non-glaucoma volunteers were recruited in this study. METHODS: Open angle glaucoma patients with visual field defect as well as non-glaucoma volunteers were asked to video record their procedures of eye drop instillation using a 5-mL plastic bottle of artificial tear solution...
2017: PloS One
https://www.readbyqxmd.com/read/29023238/severe-phenotype-of-keratitis-ichthyosis-deafness-syndrome-with-presumed-ocular-surface-squamous-neoplasia
#18
Ana Silvia Serrano-Ahumada, Vianney Cortes-González, Luz María González-Huerta, Sergio Cuevas, Luis Aguilar-Lozano, Cristina Villanueva-Mendoza
PURPOSE: The aim of this study was to describe a case of severe keratitis-ichthyosis-deafness (KID) syndrome with ocular surface squamous neoplasia. METHODS: The affected patient underwent complete ocular and systemic examinations. The molecular studies included polymerase chain reaction amplification and automated DNA sequencing of the complete gap junction beta-2 (GJB2) gene coding sequence. RESULTS: A 30-year-old man presented with generalized erythro-hyperkeratosis and deafness and complaints of decreased visual acuity, tearing, and photophobia...
October 10, 2017: Cornea
https://www.readbyqxmd.com/read/29023237/corneal-tissue-from-dry-eye-donors-leads-to-enhanced-graft-rejection
#19
Takenori Inomata, Jing Hua, Takeshi Nakao, Tina Shiang, Homer Chiang, Afsaneh Amouzegar, Reza Dana
PURPOSE: To assess the effect of dry eye disease (DED) in graft donors on dendritic cell (DC) maturation, host T-cell sensitization, and corneal allograft rejection. METHODS: Corneas of control (healthy donor) and DED mice (C57BL/6) were transplanted onto fully allogeneic naive BALB/c recipients (n = 10 mice/group). Long-term allograft survival was evaluated for 8 weeks. Corneas and draining lymph nodes (dLNs) were harvested at posttransplantation day 14 (n = 5 mice/group)...
October 10, 2017: Cornea
https://www.readbyqxmd.com/read/29022958/unilateral-lattice-corneal-dystrophy-in-a-young-female-a-unique-case-report
#20
Anuradha Raj, Renu Dhasmana, Harsh Bahadur
BACKGROUND: Unilateral lattice corneal dystrophy is a rare entity. OBJECTIVE: To highlight the evidence of unilateral lattice corneal dystrophy in a young female. CASE: A young 28 years old female presented to the outpatient department of Ophthalmology with slowly progressive diminution of vision in left eye for one month. On ophthalmological examination best corrected visual acuity (BCVA) was 20/20 and 20/40 with refractive error of plano and -0...
January 2017: Nepalese Journal of Ophthalmology
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