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https://www.readbyqxmd.com/read/28324023/long-chain-free-fatty-acid-receptor-gpr120-mediates-oil-induced-gip-secretion-through-cck-in-male-mice
#1
Akiko Sankoda, Norio Harada, Kanako Iwasaki, Shunsuke Yamane, Yuki Murata, Kimitaka Shibue, Yotsapon Thewjitcharoen, Kazuyo Suzuki, Takanari Harada, Yoshinori Kanemaru, Satoko Shimazu-Kuwahara, Akira Hirasawa, Nobuya Inagaki
Free fatty acid receptors GPR120 and GPR40 are involved in the secretion of gut hormones. GPR120 and GPR40 are expressed in enteroendocrine K-cells and their activation induces the secretion of the incretin glucose-dependent insulinotropic polypeptide (GIP). However, the role of these receptors in fat-induced GIP secretion in vivo and the associated mechanisms are unclear. In this study, we investigated corn oil-induced GIP secretion in GPR120-knockout (GPR120-/-) and GPR40-knockout (GPR40-/-) mice. Oil-induced GIP secretion was reduced by 50% and 80% in GPR120-/- and GPR40-/- mice compared to that in wild-type (WT) mice, respectively...
March 15, 2017: Endocrinology
https://www.readbyqxmd.com/read/28323908/effects-of-protease-and-non-starch-polysaccharide-enzyme-on-performance-digestive-function-activity-and-gene-expression-of-endogenous-enzyme-of-broilers
#2
Lin Yuan, Mingfa Wang, Xiaotu Zhang, Zhixiang Wang
Three hundred one-day-old male broiler chickens (Ross-308) were fed corn-soybean basal diets containing non-starch polysaccharide (NSP) enzyme and different levels of acid protease from 1 to 42 days of age to investigate the effects of exogenous enzymes on growth performance, digestive function, activity of endogenous digestive enzymes in the pancreas and mRNA expression of pancreatic digestive enzymes. For days 1-42, compared to the control chickens, average daily feed intake (ADFI) and average daily gain (ADG) were significantly enhanced by the addition of NSP enzyme in combination with protease supplementation at 40 or 80 mg/kg (p<0...
2017: PloS One
https://www.readbyqxmd.com/read/28319707/treatment-of-anaerobic-digested-effluent-in-biochar-packed-vertical-flow-constructed-wetland-columns-role-of-media-and-tidal-operation
#3
Simon Kizito, Tao Lv, Shubiao Wu, Zeeshan Ajmal, Hongzhen Luo, Renjie Dong
Three types of vertical flow constructed wetland columns (VFCWs), packed with corn cob biochar (CB-CW), wood biochar (WB-CW) and gravel (G-CW) under tidal flow operations, were comparatively evaluated to investigate anaerobic digested effluent treatment performance and mechanisms. It was demonstrated that CB-CW and WB-CW provide significantly higher removal efficiencies for organic matter (>59%), NH4(+)-N (>76%), TN (>37%) and phosphorus (>71%), compared with G-CW (22%-49%). The higher pollutants removal ability of biochar-packed VFCWs was mainly attribute to the higher adsorption ability and microbial cultivation in the porous biochar media...
March 15, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28319279/borderline-lepromatous-leprosy-erythema-nodosum-leprosum-and-a-generalized-varicella-zoster-virus-infection
#4
Cornelis Kennedy, Bernard Naafs
We report the case of a thirty-year-old man with Mid-Borderline (BB) to Borderline Lepromatous Leprosy (BL) who was admitted to the hospital with blistering lesions on his upper and lower extremities. These lesions, which were partly filled with pus rapidly developed into erosions and ulcerations with hemorrhagic crusts. Other observations at time of admission included a tender erythematous plaque on his forehead, a drop foot on the right leg, muscle atrophy in both hands, a low grade fever, and pain and swelling in his right lower jaw...
March 20, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28318791/toxicokinetics-and-toxicodynamics-of-lead-in-the-soil-invertebrate-enchytraeus-crypticus
#5
Lulu Zhang, Cornelis A M Van Gestel
The aim of the present study was to link Pb toxicokinetics to toxicodynamics in Enchytraeus crypticus. The enchytraeids were exposed for 14 d to different Pb concentrations (uptake phase) in natural Lufa 2.2 soil, followed by a 14-d elimination phase in clean soil. Pb accumulation and enchytraeid mortality were determined at different time intervals. At each exposure concentration, internal Pb concentration increased with exposure time and achieved equilibrium in approximately 7 d. Median lethal concentration (LC50) based on total Pb concentration in soil decreased with exposure time, but did not reach a steady-state level...
March 17, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28318583/effects-of-feeding-hull-less-barley-on-production-performance-milk-fatty-acid-composition-and-nutrient-digestibility-of-lactating-dairy-cows
#6
Y Yang, G Ferreira, C L Teets, B A Corl, W E Thomason, C A Griffey
The objectives of this study were to evaluate production performance, milk fatty acid composition, and nutrient digestibility in high-producing dairy cows consuming diets containing corn and hull-less barley (cultivar Amaze 10) in different proportions as the grain source. Eight primiparous and 16 multiparous Holstein cows were assigned to 1 of 4 diets in a replicated 4 × 4 Latin square design with 21-d periods. Cows were fed once daily (1200 h) by means of a Calan gate system (American Calan Inc., Northwood, NH)...
March 16, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28318577/effect-of-dietary-mineral-phosphorus-and-phytate-on-in-situ-ruminal-phytate-disappearance-from-different-concentrates-in-dairy-cows
#7
E Haese, J Möhring, H Steingass, M Schollenberger, M Rodehutscord
The first objective of this study was to determine the influence of dietary composition on the in situ disappearance of phytate (InsP6) from wheat, corn, soybean meal, and rapeseed meal [solvent-extracted, without (RSM) or with (hRSM) heat treatment] in the rumen of dairy cows. The second objective was to assess the primary degradation products of InsP6 in the rumen. Three diets differing in phosphorus and InsP6 concentration (basal diet = 0.38% P in dry matter; high-P diet = 0.56% P; high-InsP6 diet = 0.39% P) were fed to 3 ruminally fistulated lactating Jersey cows in a 3 × 3 Latin square...
March 16, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28317952/selective-perrhenate-recognition-in-pure-water-by-halogen-bonding-and-hydrogen-bonding-alpha-cyclodextrin-based-receptors
#8
Stuart P Cornes, Mark R Sambrook, Paul D Beer
Alpha-cyclodextrin based anion receptors functionalised with pendant arms containing halogen and hydrogen bond donor motifs display selective association of perrhenate in aqueous media at neutral pH. NMR and ITC anion binding investigations reveal the halogen bonding receptor to be the superior host.
March 20, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28317727/application-of-carbon-and-hydrogen-stable-isotope-analyses-to-detect-exogenous-citric-acid-in-japanese-apricot-liqueur
#9
Fumikazu Akamatsu, Takaaki Oe, Tomokazu Hashiguchi, Yuri Hisatsune, Takafumi Kawao, Tsutomu Fujii
Japanese apricot liqueur manufacturers are required to control the quality and authenticity of their liqueur products. Citric acid made from corn is the main acidulant used in commercial liqueurs. In this study, we conducted spiking experiments and carbon and hydrogen stable isotope analyses to detect exogenous citric acid used as an acidulant in Japanese apricot liqueurs. Our results showed that the δ(13)C values detected exogenous citric acid originating from C4 plants but not from C3 plants. The δ(2)H values of citric acid decreased as the amount of citric acid added increased, whether the citric acid originated from C3 or C4 plants...
August 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28317717/analytical-evaluation-of-current-starch-methods-used-in-the-international-sugar-industry-part-i
#10
Marsha Cole, Gillian Eggleston, Alexa Triplett
Several analytical starch methods exist in the international sugar industry to mitigate starch-related processing challenges and assess the quality of traded end-products. These methods use iodometric chemistry, mostly potato starch standards, and utilize similar solubilization strategies, but had not been comprehensively compared. In this study, industrial starch methods were compared to the USDA Starch Research method using simulated raw sugars. Type of starch standard, solubilization approach, iodometric reagents, and wavelength detection affected total starch determination in simulated raw sugars...
August 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28317713/a-validated-fast-difference-spectrophotometric-method-for-5-hydroxymethyl-2-furfural-hmf-determination-in-corn-syrups
#11
Jucimara Kulek de Andrade, Camila Kulek de Andrade, Emy Komatsu, Hélène Perreault, Yohandra Reyes Torres, Marcos Roberto da Rosa, Maria Lurdes Felsner
Corn syrups, important ingredients used in food and beverage industries, often contain high levels of 5-hydroxymethyl-2-furfural (HMF), a toxic contaminant. In this work, an in house validation of a difference spectrophotometric method for HMF analysis in corn syrups was developed using sophisticated statistical tools by the first time. The methodology showed excellent analytical performance with good selectivity, linearity (R(2)=99.9%, r>0.99), accuracy and low limits (LOD=0.10mgL(-1) and LOQ=0.34mgL(-1))...
August 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28315617/dietary-fructose-augments-ethanol-induced-liver-pathology
#12
Paul G Thomes, Jennifer H Benbow, Elizabeth Brandon-Warner, Kyle J Thompson, Carl Jacobs, Terrence M Donohue, Laura W Schrum
Certain dietary components when combined with alcohol exacerbate alcohol-induced liver injury (ALI). Here, we tested whether fructose, a major ingredient of the western diet, enhances the severity of ALI. We fed mice ethanol for 8 weeks in the following Lieber-DeCarli diets: (a) Regular (contains olive oil); (b) corn oil (contains corn oil); (c) fructose (contains fructose and olive oil) and (d) corn+fructose (contains fructose and corn oil). We compared indices of metabolic function and liver pathology among the different groups...
March 6, 2017: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/28315609/the-levonorgestrel-releasing-intrauterine-device-potentiates-stress-reactivity
#13
Jurate Aleknaviciute, Joke H M Tulen, Yolanda B De Rijke, Christian G Bouwkamp, Mark van der Kroeg, Mirjam Timmermans, Vincent L Wester, Veerle Bergink, Witte J G Hoogendijk, Henning Tiemeier, Elisabeth F C van Rossum, Cornelis G Kooiman, Steven A Kushner
BACKGROUND: The levonorgestrel-releasing intrauterine device (LNG-IUD) is currently recommended as a first-line contraceptive with an exclusively local intrauterine influence. However, recent clinical trials have identified side effects of LNG-IUD that appear to be systemically mediated, including depressed mood and emotional lability. METHODS: We performed two experimental studies and a cross-sectional study. For each study, women were included from three groups: LNG-IUD (0...
February 28, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28315605/green-synthesis-of-bacterial-cellulose-via-acetic-acid-pre-hydrolysis-liquor-of-agricultural-corn-stalk-used-as-carbon-source
#14
Zheng Cheng, Rendang Yang, Xu Liu, Xiao Liu, Hua Chen
Herein, bacterial cellulose (BC) was synthesized by acetobacter xylinum via organic acid pre-hydrolysis liquor of agricultural corn stalk used as carbon source. Acetic acid was applied to pretreat the corn stalk, then, the prehydrolysate was detoxified by sequential steps of activated carbon and ion exchange resin treatment prior to use as carbon source to cultivate acetobacter xylinum. Moreover, the recovery of acetic acid was achieved for facilitating the reduction of cost. The results revealed that the combination method of detoxification treatment was very effective for synthesis of BC, yield could be up to 2...
March 2, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28315601/quantitative-characterization-of-enzyme-adsorption-and-hydrolytic-performance-for-ultrafine-grinding-pretreated-corn-stover
#15
Haiyan Zhang, Longjian Chen, Junbao Li, Minsheng Lu, Lujia Han
Quantitative analysis of enzyme adsorption and hydrolysis were performed for sieve-based grinding corn stover (SGCS) and ultrafine grinding corn stover (UGCS)(1) with different enzyme consumptions. The UGCS presented significantly higher enzyme adsorption quantity (5.15mg/g for UGCS, 1.33mg/g for SGCS), higher glucose yield (49.75% for UGCS, 28.75% for SGCS) under 20FPU/g and higher binding enzyme proportion (41.32% for UGCS, 10.64% for SGCS under 5FPU/g) which can be attributed to the more accessible microstructure properties...
March 6, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28314904/the-arabidopsis-orange-ator-gene-promotes-carotenoid-accumulation-in-transgenic-corn-hybrids-derived-from-parental-lines-with-limited-carotenoid-pools
#16
Judit Berman, Uxue Zorrilla-López, Vicente Medina, Gemma Farré, Gerhard Sandmann, Teresa Capell, Paul Christou, Changfu Zhu
The AtOR gene enhances carotenoid levels in corn by promoting the formation of plastoglobuli when the carotenoid pool is limited, but has no further effect when carotenoids are already abundant. The cauliflower orange (or) gene mutation influences carotenoid accumulation in plants by promoting the transition of proplastids into chromoplasts, thus creating intracellular storage compartments that act as metabolic sink. We overexpressed the Arabidopsis OR gene under the control of the endosperm-specific wheat LMW glutenin promoter in a white corn variety that normally accumulates only trace amounts of carotenoids...
March 17, 2017: Plant Cell Reports
https://www.readbyqxmd.com/read/28306505/identification-of-an-rna-polymerase-iii-regulator-linked-to-disease-associated-protein-aggregation
#17
Olga Sin, Tristan de Jong, Alejandro Mata-Cabana, Michelle Kudron, Mohamad Amr Zaini, Francesco A Aprile, Renée I Seinstra, Esther Stroo, Roméo Willinge Prins, Céline N Martineau, Hai Hui Wang, Wytse Hogewerf, Anne Steinhof, Erich E Wanker, Michele Vendruscolo, Cornelis F Calkhoven, Valerie Reinke, Victor Guryev, Ellen A A Nollen
Protein aggregation is associated with age-related neurodegenerative disorders, such as Alzheimer's and polyglutamine diseases. As a causal relationship between protein aggregation and neurodegeneration remains elusive, understanding the cellular mechanisms regulating protein aggregation will help develop future treatments. To identify such mechanisms, we conducted a forward genetic screen in a C. elegans model of polyglutamine aggregation and identified the protein MOAG-2/LIR-3 as a driver of protein aggregation...
March 16, 2017: Molecular Cell
https://www.readbyqxmd.com/read/28303693/the-opinions-of-radiographers-nuclear-medicine-technologists-and-radiation-therapists-regarding-technology-in-health-care-a-qualitative-study
#18
Sil Aarts, Forra Cornelis, Yke Zevenboom, Patrick Brokken, Nicole van de Griend, Miriam Spoorenberg, Wendy Ten Bokum, Eveline Wouters
INTRODUCTION: New technology is continuously introduced in health care. The aim of this study was (1) to collect the opinions and experiences of radiographers, nuclear medicine technologists and radiation therapists regarding the technology they use in their profession and (2) to acquire their views regarding the role of technology in their future practice. METHODS: Participants were recruited from five departments in five hospitals in The Netherlands. All radiographers, nuclear medicine therapists and radiation therapists who were working in these departments were invited to participate (n = 252)...
March 2017: Journal of Medical Radiation Sciences
https://www.readbyqxmd.com/read/28301549/a-comprehensive-survey-of-genetic-variation-in-20-691-subjects-from-four-large-cohorts
#19
Sara Lindström, Stephanie Loomis, Constance Turman, Hongyan Huang, Jinyan Huang, Hugues Aschard, Andrew T Chan, Hyon Choi, Marilyn Cornelis, Gary Curhan, Immaculata De Vivo, A Heather Eliassen, Charles Fuchs, Michael Gaziano, Susan E Hankinson, Frank Hu, Majken Jensen, Jae H Kang, Christopher Kabrhel, Liming Liang, Louis R Pasquale, Eric Rimm, Meir J Stampfer, Rulla M Tamimi, Shelley S Tworoger, Janey L Wiggs, David J Hunter, Peter Kraft
The Nurses' Health Study (NHS), Nurses' Health Study II (NHSII), Health Professionals Follow Up Study (HPFS) and the Physicians Health Study (PHS) have collected detailed longitudinal data on multiple exposures and traits for approximately 310,000 study participants over the last 35 years. Over 160,000 study participants across the cohorts have donated a DNA sample and to date, 20,691 subjects have been genotyped as part of genome-wide association studies (GWAS) of twelve primary outcomes. However, these studies utilized six different GWAS arrays making it difficult to conduct analyses of secondary phenotypes or share controls across studies...
2017: PloS One
https://www.readbyqxmd.com/read/28300023/optimization-and-validation-of-a-residue-analysis-method-for-glyphosate-glufosinate-and-their-metabolites-in-plant-matrixes-by-liquid-chromatography-with-tandem-mass-spectrometry
#20
Dasharath P Oulkar, Sandip Hingmire, Arnab Goon, Manjusha Jadhav, Bharat Ugare, Ahammed Shabeer Thekkumpurath, Kaushik Banerjee
A sensitive and accurate LC with tandem MS (MS/MS)-based method was developed and validated for the analysis of the herbicide glyphosate, its metabolite aminomethylphosphonic acid (AMPA), and glufosinate after derivatization with 9-fluorenylmethyl chloroformate (FMOC-Cl) in various plant matrixes. The method also covers direct analysis of the glufosinate metabolites 3-methylphosphinicopropionic acid (3-MPPA) and N-acetyl-glufosinate (NAG). The homogenized samples were extracted with 0.1% formic acid in water-dichloromethane (50 + 50)...
March 23, 2017: Journal of AOAC International
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