Sabina Rinaldi, Laure Dossus, Pekka Keski-Rahkonen, Agneta Kiss, Anne-Sophie Navionis, Carine Biessy, Ruth Travis, Elisabete Weiderpass, Isabelle Romieu, Anne Kirstine Eriksen, Anne Tjonneland, Marina Kvaskoff, Marianne Canonico, Thérèse Truong, Verena Katzke, Rudolf Kaaks, Alberto Catalano, Salvatore Panico, Giovanna Masala, Rosario Tumino, Marko Lukic, Karina Standahl Olsen, Raul Zamora-Ros, Carmen Santiuste, Amaia Aizpurua Atxega, Marcela Guevara, Miguel Rodriguez-Barranco, Maria Sandstrom, Joakim Hennings, Martin Almquist, Elom Aglago Kouassivi, Sofia Christakoudi, Marc Gunter, Silvia Franceschi
Thyroid cancer (TC) is substantially more common in women than in men, pointing to a possible role of sex steroid hormones. We investigated the association between circulating sex steroid hormones, sex hormone binding globulin (SHBG) and the risk of differentiated TC in men and women within the European Prospective Investigation into Cancer and nutrition (EPIC) cohort. During follow-up, we identified 333 first primary incident cases of differentiated TC (152 in pre/peri-menopausal women, 111 in post-menopausal women, and 70 in men) and 706 cancer-free controls...
February 15, 2024: International Journal of Cancer. Journal International du Cancer