keyword
MENU ▼
Read by QxMD icon Read
search

perimenopause

keyword
https://www.readbyqxmd.com/read/29111860/identification-of-the-gender-specific-health-needs-of-women-following-lung-transplantation
#1
Emily E Robertson, Robin J Bell, Penelope J Robinson, Greg Snell, Bronwyn Levvey, Helen M Whitford, Jane Harris, Susan R Davis
BACKGROUND: Little is known of the prevalence and severity of menstrual dysfunction, climacteric symptoms, pelvic floor disorders, sexual problems, and psychological wellbeing after lung transplantation in women. MATERIALS AND METHODS: Adult female lung transplant recipients, attending the Alfred Hospital Lung Transplant Service in Melbourne, Australia participated in a women's health, cross-sectional questionnaire-based study. RESULTS: The 123 of 149 potential participants were recruited between September 2014 and July 2015...
November 7, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/29108778/the-timing-and-duration-of-estradiol-treatment-in-a-rat-model-of-the-perimenopause-influences-on-social-behavior-and-the-neuromolecular-phenotype
#2
Alexandra N Garcia, Christina Depena, Kelsey Bezner, Weiling Yin, Andrea C Gore
This study tested the effects of timing and duration of estradiol (E2) treatment, factors that are clinically relevant to hormone replacement in perimenopausal women, on social behavior and expression of genes in brain regions that regulate these behaviors. Female rats were ovariectomized (OVX) at 1year of age, roughly equivalent to middle-age in women, and given E2 or vehicle for different durations (3 or 6months) and timing (immediately or after a 3-month delay) relative to OVX. Social and ultrasonic vocalization (USV) behaviors were assessed at the 3 and 6month timepoints, and the rats' brains were then used for gene expression profiling in hypothalamus (supraoptic nucleus, paraventricular nucleus), bed nucleus of the stria terminalis, medial amygdala, and prefrontal cortex using a 48-gene qPCR platform...
November 8, 2017: Hormones and Behavior
https://www.readbyqxmd.com/read/29076687/symptoms-of-menopause-in-peri-and-postmenopausal-women-and-their-attitude-towards-them
#3
Kausar Inayat, Nargis Danish, Lubna Hassan
BACKGROUND: The climacteric or perimenopause is the transitional phase during which reproductive function ceases. The average age of the menopause is 51.4 years with a duration of two years. Symptomatology include: vasomotor, psychological, urogenital/sexual, skin, menstrual irregularities and others. The objective was to study the attitude of these women towards menopause. METHODS: In this cross-sectional study, 500 women were included. RESULTS: Palpitations and headaches were found in 30% and 32% respectively in perimenopausal women compared to 16% and 20% in postmenopausal women...
July 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/29071997/-effect-of-electroacupuncture-on-hypothalamus-pituitary-ovary-hpo-axis-in-rats-with-peri-menopausal-depression
#4
Xi-Rong Jiang, Lu Ren, Chun-Ri Li
OBJECTIVE: To observe the effect of electroacupuncture (EA) on the hormones derived from the hypothalamus-pituitary-ovary (HPO) axis, so as to explore the neuroendocrine mechanism induced by EA on rats with perimenopausal depression disorder. METHODS: Sixty female sprague-dawley rats were randomly divided into blank control group, model group, sham-operation (sham) group, clomipramine group, and electroacupuncture (EA) group, with 12 rats in each group. Perimenopausal depression model was established by bilateral ovariectomy combined with chronic unpredictable stimulation...
February 25, 2017: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29069110/vortioxetine-for-major-depressive-disorder-vasomotor-and-cognitive-symptoms-associated-with-the-menopausal-transition
#5
Marlene P Freeman, Laura J Cheng, Danna Moustafa, Abigail Davies, Alexandra Z Sosinsky, Betty Wang, Laura F Petrillo, Charlotte Hogan, Lee S Cohen
BACKGROUND: In a preliminary trial, we assessed the efficacy of vortioxetine for major depressive disorder (MDD) during the menopausal transition. Secondary outcomes included hot flashes (HFs), anxiety, and cognitive complaints. METHODS: Perimenopausal and early postmenopausal women with MDD (N = 27) received 8 weeks of open-label, flexible-dose treatment with vortioxetine. The Montgomery-Åsberg Depression Rating Scale (MADRS) was the primary outcome measure. Secondary measures included: HF frequency, the Greene Climacteric Scale (GCS), Menopause-Specific Quality of Life Questionnaire (MEN-QOL), Beck Anxiety Inventory (BAI), Cognitive and Physical Functioning Questionnaire (CPFQ), Digit Symbol Substitution Test (DSST), and Cogstate testing...
November 2017: Annals of Clinical Psychiatry: Official Journal of the American Academy of Clinical Psychiatrists
https://www.readbyqxmd.com/read/29055024/serum-lipid-vitamin-d-levels-and-obesity-in-perimenopausal-and-postmenopausal-women-in-non-manual-employment
#6
Jarosław Pinkas, Iwona Bojar, Mariusz Gujski, Joanna Bartosińska, Alfred Owoc, Dorota Raczkiewicz
BACKGROUND Increasing age, increased body mass index (BMI), and abnormal lipid profiles contribute to an increased risk of vitamin D deficiency. Women who have a perimenopausal and postmenopausal reduction in estrogen levels are a high-risk group for vitamin D deficiency. The aims of this study were to compare the serum vitamin D levels, lipid profile, and BMI between perimenopausal and postmenopausal women in non-manual employment, and to determine whether there were any interdependent factors. MATERIAL AND METHODS Three hundred women in non-manual employment, aged between 44-66 years, were divided into three groups: early perimenopausal; late perimenopausal; and postmenopausal...
October 21, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29044004/research-on-the-influence-of-bilateral-oophorectomy-on-the-bmd-body-components-and-sex-hormone-of-women-during-the-perimenopause
#7
HaiLi Wang, Chuchu Wang, Lei Sun, Shiyuan Zhou, Fengyu Wang
To investigate the effect of bilateral oophorectomy on bone mineral density, body composition and sex hormone of peri-menopause women. 33 cases of peri-menopause women patients performed bilateral oophorectomy were chosen from xxx gynaecology and obstetrics department of xxx hospital from January 1st,2014 to Dec31th, 2014. And the 33 cases were taken as ovariectomy group. 35 women who were the naturally postmenopausal after menopause collected in clinic and in the same period with the patients of ovariectomy group were taken in control group...
July 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29040218/perimenopausal-depression-and-early-menopause-cause-or-consequence
#8
Katherine M Reding, Peter J Schmidt, David R Rubinow
No abstract text is available yet for this article.
October 16, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29024986/stromal-fibroblasts-from-perimenopausal-endometrium-exhibit-a-different-transcriptome-than-those-from-the-premenopausal-endometrium
#9
David W Erikson, Fatima Barragan, Terhi T Piltonen, Joseph C Chen, Shaina Balayan, Juan C Irwin, Linda C Giudice
Human endometrium undergoes extensive regeneration on a cyclic basis in premenopausal women and likely occurs through the contribution of stem/progenitor cells. Menopause results in the permanent cessation of menstrual cycles and is preceded by perimenopause, a period of several years in which endocrine and biological changes occur and is a period of risk for endometrial proliferative disorders. The objectives of this study were to identify endometrial mesenchymal stem cells (eMSC) and endometrial stromal fibroblasts (eSF) in endometrium of perimenopausal women and perform expression profile analysis of perimenopausal eMSC and eSF to gain insight into the biology of stem/progenitor and lineage cell populations during the transition to menopause...
September 1, 2017: Biology of Reproduction
https://www.readbyqxmd.com/read/29021811/significance-of-finding-benign-endometrial-cells-in-women-40-45-versus-46-years-or-older-on-papanicolaou-tests-and-histologic-follow-up
#10
Shanna M Colletti, Ghassan A Tranesh, Aziza Nassar
BACKGROUND: The 2014 Bethesda System recommends reporting the finding of benign-appearing, exfoliated endometrial cells on Papanicolaou (Pap) tests in women aged 45 years and older. We aimed to determine the significance of normal endometrial cells on liquid-based Pap tests in women aged 40 years and older and to correlate this finding with clinical factors and cytologic/histologic follow-up. MATERIALS AND METHODS: We retrospectively identified all women aged 40 years and older who had benign endometrial cells (BECs) on Pap tests at our institution during a 6-year period...
2017: CytoJournal
https://www.readbyqxmd.com/read/29016679/perimenopause-and-emergence-of-an-alzheimer-s-bioenergetic-phenotype-in-brain-and-periphery
#11
Lisa Mosconi, Valentina Berti, Crystal Guyara-Quinn, Pauline McHugh, Gabriella Petrongolo, Ricardo S Osorio, Christopher Connaughty, Alberto Pupi, Shankar Vallabhajosula, Richard S Isaacson, Mony J de Leon, Russell H Swerdlow, Roberta Diaz Brinton
After advanced age, female sex is the major risk factor for Alzheimer's disease (AD). The biological mechanisms underlying the increased AD risk in women remain largely undetermined. Preclinical studies identified the perimenopause to menopause transition, a neuroendocrine transition state unique to the female, as a sex-specific risk factor for AD. In animals, estrogenic regulation of cerebral glucose metabolism (CMRglc) falters during perimenopause. This is evident in glucose hypometabolism and decline in mitochondrial efficiency which is sustained thereafter...
2017: PloS One
https://www.readbyqxmd.com/read/28994639/migraine-menopause-and-hormone-replacement-therapy
#12
E Anne MacGregor
Perimenopause marks a period of increased migraine prevalence in women and many women also report troublesome vasomotor symptoms. Migraine is affected by fluctuating estrogen levels with evidence to support estrogen 'withdrawal' as a trigger of menstrual attacks of migraine without aura, while high estrogen levels can trigger migraine aura. Maintaining a stable estrogen environment with estrogen replacement can benefit estrogen-withdrawal migraine particularly in women who would also benefit from relief of vasomotor symptoms...
January 1, 2017: Post Reproductive Health
https://www.readbyqxmd.com/read/28990664/hormone-receptors-analysis-in-idiopathic-progressive-subglottic-stenosis
#13
Ivana Fiz, Zeid Bittar, Cesare Piazza, Jan Constantin Koelmel, Federico Gatto, Diego Ferone, Francesco Fiz, Diana Di Dio, Alexander Bosse, Giorgio Peretti, Christian Sittel
OBJECTIVE: Idiopathic subglottic stenosis predominantly affects fertile and perimenopausal women. Estrogens and/or progesterone have been proposed as mediators of its pathogenesis by stimulating collagen deposition within the upper airway. We evaluated the presence and expression of estrogen-alpha (ER-α), estrogen-beta (ER-β), and progesterone receptors (PR) in idiopathic stenotic patients. STUDY DESIGN: A retrospective analysis on 42 surgical specimens from idiopathic stenosis female patients (mean age, 52...
October 9, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28969213/severity-and-frequency-of-menopausal-symptoms-in-middle-aged-women-rasht-iran
#14
Marzieh Masjoudi, Marjan Akhavan Amjadi, Ehsan Kazem Nezhad Leyli
INTRODUCTION: Menopause is a natural event in women's life. Some studies have shown that, these symptoms can lead to low quality of life. AIM: To identify the severity and frequency of menopausal symptoms in different stages of menopause, in a group of middle aged women. MATERIALS AND METHODS: This cross-sectional study was conducted on 646 women aged 45-60 years in Rasht, Iran, who were included in the study by convenience sampling method...
August 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28964870/hemostasis-and-uterine-contraction-promoting-effect-of-the-extract-from-drugs-in-the-zi-yin-tiao-jing-granule-a-traditional-chinese-compound-preparation
#15
Qing Tang, Sheng Yang, Jie Tong, Xu Li, Junjie Wu, Senhong Wang, Jifen Zhang, Yi Chen, Xiaoyu Xu
ETHNOPHARMACOLOGICAL RELEVANCE: Zi-Yin-Tiao-Jing granule (ZG) is a traditional Chinese medicine compound preparation for perimenopausal dysfunctional uterine bleeding. It is made from 9 Chinese crude drugs based on a modified traditional Chinese prescription recorded in Fu Qingzhu Nvke as Guben Zhibeng Tang. AIM OF THE STUDY: This study aimed to investigate the hemostasis and uterine contraction promoting effect of quality controlled ZG extract on animals as a preclinical study...
September 28, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28958685/saikosaponin-a-attenuates-perimenopausal-depression-like-symptoms-by-chronic-unpredictable-mild-stress
#16
Xue-Qin Chen, Shu-Jiao Chen, Wen-Na Liang, Miao Wang, Cheng-Fu Li, Shuang-Shuang Wang, Shu-Qi Dong, Li-Tao Yi, Can-Dong Li
Accumulating studies have shown that a traditional Chinese decoction Chaihu-Shugan-San produced the antidepressant-like effects in rodents including in perimenopausal. Previous studies and our preliminary study indicated that saikosaponin A, one of the main constituents of Chaihu-Shugan-San, enhanced brain-derived neurotrophic factor (BDNF) expression in rats. Herein, this study aimed to evaluate the antidepressant-like effects of saikosaponin A in perimenopausal rats exposed to chronic unpredictable mild stress (CUMS)...
September 25, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28945159/a-new-subtype-of-chronic-daily-headache-presenting-in-older-women
#17
Todd D Rozen
OBJECTIVE: To describe a new subtype of chronic daily headache in women of a specific age group. METHODS: Case series. RESULTS: Eight patients were included in the presented case series. The average age of onset of this distinct headache condition is 57 years. All patients were either perimenopausal or in menopause when the headaches started. The syndrome is marked by bilateral head pain that starts daily from onset and is typically at its most severe intensity the first thing in the morning before arising or when in the supine position...
September 25, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28937311/it-s-not-as-bad-as-you-think-menopausal-representations-are-more-positive-in-postmenopausal-women
#18
Lydia Brown, Valerie Brown, Fiona Judd, Christina Bryant
INTRODUCTION: The menopausal transition is associated with underlying hormonal changes that can contribute to a range of physical and emotional symptoms. Psycho-social factors including attitudes and internal representations play a central role in women's experience of the menopause, but very little is known about how representations might differ across menopausal stages. METHODS: A sample of 387 women aged 40-60 completed a postal questionnaire that included the menopausal representations questionnaire, the emotional representation subscale adapted from the illness perception questionnaire, and data on menopausal status...
September 22, 2017: Journal of Psychosomatic Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28926513/pharmacokinetics-and-safety-profile-of-single-dose-administration-of-an-estrogen-receptor-%C3%AE-selective-phytoestrogenic-phytoserm-formulation-in-perimenopausal-and-postmenopausal-women
#19
Gerson Hernandez, Liqin Zhao, Adrian A Franke, Yu-Ling Chen, Wendy J Mack, Roberta D Brinton, Lon S Schneider
OBJECTIVE: Selected estrogen receptor β-selective phytoestrogen (phytoSERM), a preparation of genistein, daidzein, and S-equol, has an 83-fold selective affinity for estrogen receptor (ER) β, and may promote neuronal survival and estrogenic mechanisms in the brain without exerting feminizing activity in the periphery. The aim of this study was to assess the safety, tolerability, and single-dose pharmacokinetics of the phytoSERM formulation in perimenopausal and postmenopausal women...
September 18, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28922102/sleep-duration-and-quality-among-women-aged-40-59-by-menopausal-status
#20
Anjel Vahratian
Data from the National Health Interview Survey, 2015 ? Among those aged 40?59, perimenopausal women (56.0%) were more likely than postmenopausal (40.5%) and premenopausal (32.5%) women to sleep less than 7 hours, on average, in a 24-hour period. ? Postmenopausal women aged 40?59 were more likely than premenopausal women aged 40?59 to have trouble falling asleep (27.1% compared with 16.8%, respectively), and staying asleep (35.9% compared with 23.7%), four times or more in the past week. ? Postmenopausal women aged 40?59 (55...
September 2017: NCHS Data Brief
keyword
keyword
33761
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"