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https://www.readbyqxmd.com/read/27919426/diagnostic-accuracy-of-treadmill-exercise-tests-among-chinese-women-with-coronary-artery-diseases-a-systematic-review-and-meta-analysis
#1
REVIEW
Yi Sun, Wei Li, Lu Yin, Limei Wei, Yang Wang
BACKGROUND: The treadmill exercise test (TET) is one of the most common noninvasive diagnosis approaches for ischemic heart diseases, but potential reduction of TET accuracy among Chinese female patients was ignored by most studies, especially in perimenopause women. Hence, we aim to perform a systematic review and meta-analysis evaluating the TET diagnostic accuracy for Chinese women compared with coronary angiography (CAG). METHODS: PubMed, MEDLINE, EMBASE, CNKI and WANFANG (1990 to 2015) were performed to identify studies assessing the diagnostic accuracy of TET versus CAG...
November 9, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27918164/-the-possibility-of-using-progesterone-receptor-modulators-in-the-treatment-of-myomas
#2
O Šimetka, J Klát, S Bajsová
OBJECTIVE: To summarize the knowledge about the effect of selective progesterone receptor modulators and their use in the treatment of myomas in women of childbearing age and in perimenopause. DESIGN: Review article. RESULTS: Long-term treatment with ulipristal acetate maximizes its effectiveness, it helps to achieve faster bleeding control and increases the number of pa-tients with fibroid volume reduction of more than 50%. Ulipristal acetate is the most effective drug in the medical treatment of myomas and its use will change the approach to surgical treatment...
2016: Ceská Gynekologie
https://www.readbyqxmd.com/read/27898258/estradiol-therapy-and-breast-cancer-risk-in-perimenopausal-and-postmenopausal-women-a-systematic-review-and-meta-analysis
#3
Zhilan Yang, Ying Hu, Jing Zhang, Liangzhi Xu, Rujun Zeng, Deying Kang
OBJECTIVE: To investigate the association between estradiol therapy and incidence of breast cancer, taking into consideration of different types of combined progestogen, the duration of exposure and the type of regimen. METHOD: A systematic review and meta-analysis. RESULT: A total of 14 studies were included in our study. In estradiol-only therapy analysis, meta-analysis resulted a pooled OR =0.90, 95% CI (0.40, 2.02) from the RCTs and pooled OR = 1...
November 29, 2016: Gynecological Endocrinology
https://www.readbyqxmd.com/read/27896261/giant-invasive-mole-presenting-as-a-cause-of-abdominopelvic-mass-in-a-perimenopausal-woman-an-unusual-presentation-of-a-rare-pathology
#4
Alpaslan Akyol, Memet Şimşek, Özlem Üçer
Invasive mole is a benign gestational trophoblastic disease that arises from the myometrial invasion of any gestational event via direct extension through tissue or vascular structures. Invasive mole (and other gestational trophoblastic diseases) may present with life-threatening complications including uterine perforation, excessive bleeding, acute hemoperitoneum, and abdominal pain. We report a case of invasive mole presenting as abdominal distention in a 51-year-old perimenopausal woman (gravida 12, para 12, abortion 0)...
November 2016: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/27895667/attitude-to-the-menopause-and-sex-amongst-middle-aged-women-in-a-family-medicine-clinic-in-ibadan-nigeria
#5
Folasade Adenike Bello, Olufunmilola Olutosin Daramola
Background. Menopause is the expected end of reproductive life. Having a positive attitude towards it has been shown to result in a positive experience, while a negative attitude is associated with negative experiences and symptoms. Traditionally, women often abstain from sex after menopause. The study aimed to determine the level of awareness and perceptions about the menopause and sex in perimenopausal women attending a general outpatient clinic. Methods. Women over 40 years were recruited from the Family Medicine Department of University College Hospital, excluding those who were menopausal...
2016: Obstetrics and Gynecology International
https://www.readbyqxmd.com/read/27886700/sj%C3%A3-gren-syndrome-and-other-causes-of-sicca-in-older-adults
#6
REVIEW
Alan N Baer, Brian Walitt
Dry eye and dry mouth symptoms are each reported by up to 30% of persons more than 65 years of age, particularly in women. Medication side effects are the most common contributing factors. The evaluation of these symptoms requires measures of ocular and oral dryness. Sjögren syndrome is the prototypic disease associated with dryness of the eyes and mouth and predominantly affects women in their perimenopausal and postmenopausal years. In addition to topical treatment of the mucosal dryness, patients with Sjögren syndrome may require treatment with systemic immunomodulatory and immunosuppressive agents to manage a variety of extraglandular manifestations...
February 2017: Clinics in Geriatric Medicine
https://www.readbyqxmd.com/read/27882756/-the-use-of-selective-progesterone-receptor-modulators-in-the-treatment-of-myomas
#7
O Šimetka, J Klát
OBJECTIVE: To summarize the knowledge of the effect of selective progesterone receptor modulators and their use in the treatment of myomas in women of childbearing age and in perimenopause. DESIGN: Review articleResults: Long-term treatment with ulipristal acetate maximizes its effectiveness, it helps to achieve faster bleeding control and increases the number of patients with fibroid volume reduction of more than 50%. Ulipristal acetate is the most effective drug in the medical treatment of myomas and its use will change the approach to surgical treatment...
2016: Ceská Gynekologie
https://www.readbyqxmd.com/read/27882238/large-uterine-pyomyoma-in-a-perimenopausal-female-a-case-report-and-review-of-50-reported-cases-in-the-literature
#8
Naoyuki Iwahashi, Yasushi Mabuchi, Michihisa Shiro, Shigetaka Yagi, Sawako Minami, Kazuhiko Ino
Pyomyoma is a rare complication, which withoug antibiotics or surgical intervention, may cause sepsis and mortality. The present study reported a case of large uterine pyomyoma in a perimenopausal female. A 53-year-old multigravida woman was referred to the Department of Obstetrics and Gynecology (Wakayama Medical University, Wakayama, Japan) due to progressive abdominal distension. The patient presented with anemia gravis, severe inflammatory reaction and cachexia. Computed tomography revealed a large unilocular mass, 50 cm in size, with an irregular surface and thickened wall, occupying the entire abdomen...
November 2016: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/27867758/naturally-occurring-changes-in-estradiol-concentrations-in-the-menopause-transition-predict-morning-cortisol-and-negative-mood-in-perimenopausal-depression
#9
Jennifer L Gordon, Tory A Eisenlohr-Moul, David R Rubinow, Leah Schrubbe, Susan S Girdler
Risk of depression increases considerably during the menopause transition (or perimenopause) - the 5-6 years surrounding the last menstrual period. While the mechanisms underlying this increased risk are unknown, we have hypothesized that excessive estradiol (E2) fluctuation, which accompanies the perimenopause, may be implicated. We have furthermore proposed that dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis may underlie E2 fluctuation's effect on mood. This study examined the relationship between weekly changes in salivary E2, salivary cortisol levels and weekly mood in 30 perimenopausal women recruited to achieve equal numbers of women with current depression, past depression, and no history of depression...
September 2016: Clinical Psychological Science
https://www.readbyqxmd.com/read/27863600/herbal-medicine-for-low-sexual-desire-in-menopausal-women-a-clinical-review
#10
REVIEW
Janice Pellow, Linda McGrath
Many women typically experience a significant reduction in sexual desire during the late perimenopausal and early postmenopausal stages, with the biggest decline in sexual desire occurring from three years prior to two years after the final menstrual period. Despite being a prevalent female complaint, currently no standard treatment for low sexual desire exists. Herbal medicines have been used therapeutically all around the world, and are an important component of Traditional and Complementary Medicine. There have been numerous trials and pharmacological studies of specific herbal preparations related to the treatment of low sexual desire...
November 2016: Complementary Therapies in Clinical Practice
https://www.readbyqxmd.com/read/27860535/is-there-an-association-between-bone-mineral-density-and-mammographic-density-a-systematic-review
#11
Jong Min Lee, Susan Holley, Catherine Appleton, Adetunji T Toriola
INTRODUCTION: Both bone mineral density (BMD) and breast density are related to reproductive hormone levels. This suggests that BMD and breast density could be meaningfully associated, and serve as surrogate markers for breast cancer risk. However, few studies have investigated the association of BMD with percent mammographic density, making it difficult to draw meaningful conclusions. MATERIALS AND METHODS: We conducted a systematic review of studies published in electronic databases till April 2016 using the following search terms: "bone density," "bone mineral density," "mammographic breast density," "breast density," and "mammographic density...
November 18, 2016: Journal of Women's Health
https://www.readbyqxmd.com/read/27855428/middle-aged-female-depression-in-perimenopausal-period-and-square-dance-intervention
#12
Lei Gao, Linlin Zhang, Hua Qi, Louyis Petridis
BACKGROUND: Depression is one of the most common psychiatric illnesses among perimenopausal women. Currently, drug treatments for the disorder tend to have higher risks than other forms of treatment. On the contrary, aerobic exercise can effectively relieve menopausal syndrome among perimenopausal women. Square dance, a kind of aerobic exercise favored by middle-aged women in China, could be a beneficial intervention for perimenopausal depression. SUBJECTS AND METHODS: A total of 321 women in perimenopause were chosen from Nangang Community, DaoLi Community, and Daowai Community in Harbin, Heilongjiang Province, from September 2015 through April 2016...
December 2016: Psychiatria Danubina
https://www.readbyqxmd.com/read/27842995/antim%C3%A3-llerian-hormone-levels-and-cardiometabolic-risk-in-young-women-with-polycystic-ovary-syndrome
#13
Rebecca A Feldman, Kathleen O'Neill, Samantha F Butts, Anuja Dokras
OBJECTIVE: To determine the association between antimüllerian hormone (AMH) levels and metabolic syndrome (MetSyn) in young women with polycystic ovary syndrome (PCOS). DESIGN: Cross-sectional study. SETTING: Academic PCOS center. PATIENT(S): A total of 252 women aged 18-46 years with PCOS. INTERVENTION: None. MAIN OUTCOME MEASURE(S): Association of AMH with markers of cardiometabolic risk and MetSyn...
November 11, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27824682/treating-schizophrenia-during-menopause
#14
Amnon Brzezinski, Noa A Brzezinski-Sinai, Mary V Seeman
OBJECTIVE: The aim of this review is to examine three questions: What are the risks and benefits of treating women with schizophrenia with hormone therapy (HT) at menopause? Should the antipsychotic regimen be changed at menopause? Do early- and late-onset women with schizophrenia respond differently to HT at menopause? METHODS: MEDLINE databases for the years 1990 to 2016 were searched using the following interactive terms: schizophrenia, gender, menopause, estrogen, and hormones...
November 7, 2016: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/27824681/sex-differences-in-episodic-memory-in-early-midlife-impact-of-reproductive-aging
#15
Dorene M Rentz, Blair K Weiss, Emily G Jacobs, Sara Cherkerzian, Anne Klibanski, Anne Remington, Harlyn Aizley, Jill M Goldstein
OBJECTIVE: Few have characterized cognitive changes with age as a function of menopausal stage relative to men, or sex differences in components of memory in early midlife. The study aim was to investigate variation in memory function in early midlife as a function of sex, sex steroid hormones, and reproductive status. METHODS: A total of 212 men and women aged 45 to 55 were selected for this cross-sectional study from a prenatal cohort of pregnancies whose mothers were originally recruited in 1959 to 1966...
November 7, 2016: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/27801705/change-in-sexual-functioning-over-the-menopausal-transition-results-from-the-study-of-women-s-health-across-the-nation
#16
Nancy E Avis, Alicia Colvin, Arun S Karlamangla, Sybil Crawford, Rachel Hess, L Elaine Waetjen, Maria Brooks, Ping G Tepper, Gail A Greendale
OBJECTIVE: The aim of the study was to identify whether there is a decline in sexual functioning related to the menopausal transition or to hysterectomy. METHODS: In a cohort of 1,390 women aged 42 to 52, with intact uterus and at least one ovary, not using hormone therapy, and pre- or early perimenopausal at baseline, we fit piecewise linear growth curves to 5,798 repeated measurements (seven visits spanning 14.5 y) of a sexual functioning score (range, 5-25) as a function of time relative to date of final menstrual period (FMP) or hysterectomy...
October 31, 2016: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/27793768/cognitive-changes-across-the-menopause-transition-a-longitudinal-evaluation-of-the-impact-of-age-and-ovarian-status-on-spatial-memory
#17
Stephanie V Koebele, Sarah E Mennenga, Ryoko Hiroi, Alicia M Quihuis, Lauren T Hewitt, Mallori L Poisson, Christina George, Loretta P Mayer, Cheryl A Dyer, Leona S Aiken, Laurence M Demers, Catherine Carson, Heather A Bimonte-Nelson
Cognitive changes that occur during mid-life and beyond are linked to both aging and the menopause transition. Studies in women suggest that the age at menopause onset can impact cognitive status later in life; yet, little is known about memory changes that occur during the transitional period to the postmenopausal state. The 4-vinylcyclohexene diepoxide (VCD) model simulates transitional menopause in rodents by depleting the immature ovarian follicle reserve and allowing animals to retain their follicle-deplete ovarian tissue, resulting in a profile similar to the majority of perimenopausal women...
October 26, 2016: Hormones and Behavior
https://www.readbyqxmd.com/read/27793547/-clinical-trial-with-educational-intervention-in-perimenopausal-women-with-cardiovascular-risk-factor
#18
Anxela Soto-Rodríguez, José Luís García-Soidán, Manuel de Toro-Santos, Manuel Rodríguez-González, M Jesús Arias-Gómez, María Reyes Pérez-Fernández
OBJECTIVE: To assess whether an educational intervention in women in perimenopausal age with diabetes mellitus, hypertension and/or dyslipidemia could improve aspects of quality of life and exercise. METHODS: A randomized clinical trial. VARIABLES: physical activity, quality of life and weight in women aged 45-60 years (n = 320) at time 0 and 12 months after surgery. intervention group (IG): 3 interactive workshops on cardiovascular disease prevention and control group (CG): information by mail...
October 25, 2016: Gaceta Sanitaria
https://www.readbyqxmd.com/read/27784616/the-role-of-leiomyomas-in-the-genesis-of-abnormal-uterine-bleeding-aub
#19
REVIEW
Ricardo Bassil Lasmar, Bernardo Portugal Lasmar
Abnormal uterine bleeding (AUB) is the major complaint in approximately one-third of gynecological visits in premenopausal women, and in >70% of appointments of perimenopausal and postmenopausal women. Uterine myoma is one of the main causes of AUB during menacme, especially when it is submucosal. The association of myoma and AUB may be related to several factors, from local alterations of angiogenic and vasoactive substances to changes in uterine contractility. The objective of this paper is to show the different associations of myoma and AUB...
October 1, 2016: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/27783370/the-short-term-effect-of-weight-loss-surgery-on-volumetric-breast-density-and-fibroglandular-volume
#20
Nasreen A Vohra, Swapnil D Kachare, Paul Vos, Bruce F Schroeder, Olga Schuth, Dylan Suttle, Timothy L Fitzgerald, Jan H Wong, Kathryn M Verbanac
PURPOSE: Obesity and breast density are both associated with an increased risk of breast cancer and are potentially modifiable. Weight loss surgery (WLS) causes a significant reduction in the amount of body fat and a decrease in breast cancer risk. The effect of WLS on breast density and its components has not been documented. Here, we analyze the impact of WLS on volumetric breast density (VBD) and on each of its components (fibroglandular volume and breast volume) by using three-dimensional methods...
October 26, 2016: Obesity Surgery
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