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https://www.readbyqxmd.com/read/29764605/perception-matters-stressful-life-events-increase-breast-cancer-risk
#1
Avital Fischer, Argyrios Ziogas, Hoda Anton-Culver
OBJECTIVE: The relationship between psychological stress and breast cancer risk is unclear. The present study sought to understand how stressfulness appraisal of salient Life Events (LEs) influences breast cancer risk. METHODS: A case-control design was used and included 664 female cases identified through the Cancer Surveillance Program of Orange County, CA and 203 female population-based controls. A LE questionnaire determined if events occurred prior to breast cancer diagnosis and if these events were considered to be stressful or not...
July 2018: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/29700350/mindfulness-based-stress-reduction-mbsr-or-psychoeducation-for-the-reduction-of-menopausal-symptoms-a-randomized-controlled-clinical-trial
#2
Carmen Wong, Benjamin Hon-Kei Yip, Ting Gao, Kitty Yu Yuk Lam, Doris Mei Sum Woo, Annie Lai King Yip, Chloe Yu Chin, Winnie Pui Yin Tang, Mandy Mun Tse Choy, Katrina Wai Key Tsang, Suzanne C Ho, Helen Shuk Wah Ma, Samuel Yeung Shan Wong
Psychological and behavioural interventions may be effective in reducing menopause-related symptoms. This randomized controlled trial aimed to evaluate the effectiveness of Mindfulness-based Stress Reduction (MBSR) in reducing menopause-related symptoms by comparing with an active control group, the menopause education control (MEC). Symptomatic peri-menopausal and post-menopausal women with mild to moderate symptoms were recruited. The primary outcome was overall menopausal symptoms measured by modified Greene Climacteric Scale (GCS)...
April 26, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29696756/female-reproductive-history-and-risk-of-type-2-diabetes-a-prospective-analysis-of-126-721-women
#3
Nirmala Pandeya, Rachel R Huxley, Hsin-Fang Chung, Annette J Dobson, Diana Kuh, Rebecca Hardy, Janet E Cade, Darren C Greenwood, Graham G Giles, Fiona Bruinsma, Panayotes Demakakos, Mette Kildevaeld Simonsen, Hans-Olov Adami, Elisabete Weiderpass, Gita D Mishra
AIMS: Female reproductive history has been inconsistently associated with risk of type 2 diabetes. We examined the prospective associations between aspects of a woman's reproductive history and incident diabetes. METHODS: This study pooled 126,721 middle-aged women's individual data from eight cohort studies contributing to the International Collaboration for a Life Course Approach to Reproductive Health and Chronic Disease Events (InterLACE). Associations between age at menarche, age at first birth, parity and menopausal status with incident diabetes were examined using generalized linear mixed models with binomial distribution and robust variance...
April 25, 2018: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/29687165/mechanism-underlying-the-effects-of-estrogen-deficiency-on-otoconia
#4
Liping Yang, Yinfang Xu, Yan Zhang, Sarath Vijayakumar, Sherri M Jones, Yunxia Yesha Wang Lundberg
Otoconia-related vertigo and balance deficits, particularly benign paroxysmal positional vertigo (BPPV), are common. Our recent studies in humans show that, while BPPV prevalence greatly increases with age in both genders, peri-menopausal women are especially susceptible. In the present study, we show that bilateral ovariectomized (OVX) mice have significant balance behavioral deficits, and that estrogen deficiency compromises otoconia maintenance and anchoring by reducing the expression of otoconial component and anchoring proteins...
April 23, 2018: Journal of the Association for Research in Otolaryngology: JARO
https://www.readbyqxmd.com/read/29474360/animal-versus-plant-protein-and-adult-bone-health-a-systematic-review-and-meta-analysis-from-the-national-osteoporosis-foundation
#5
REVIEW
Marissa M Shams-White, Mei Chung, Zhuxuan Fu, Karl L Insogna, Micaela C Karlsen, Meryl S LeBoff, Sue A Shapses, Joachim Sackey, Jian Shi, Taylor C Wallace, Connie M Weaver
BACKGROUND: Protein may have both beneficial and detrimental effects on bone health depending on a variety of factors, including protein source. OBJECTIVE: The aim was to conduct a systematic review and meta-analysis evaluating the effects of animal versus plant protein intake on bone mineral density (BMD), bone mineral content (BMC) and select bone biomarkers in healthy adults. METHODS: Searches across five databases were conducted through 10/31/16 for randomized controlled trials (RCTs) and prospective cohort studies in healthy adults that examined the effects of animal versus plant protein intake on 1) total body (TB), total hip (TH), lumbar spine (LS) or femoral neck (FN) BMD or TB BMC for at least one year, or 2) select bone formation and resorption biomarkers for at least six months...
2018: PloS One
https://www.readbyqxmd.com/read/29471055/brain-insulin-signalling-glucose-metabolism-and-females-reproductive-aging-a-dangerous-triad-in-alzheimer-s-disease
#6
REVIEW
A I Duarte, M S Santos, C R Oliveira, P I Moreira
Alzheimer's disease (AD) constitutes a major socioeconomic challenge due to its disabling features and the rise in prevalence (especially among (peri)menopausal women and type 2 diabetes patients). The precise etiopathogenesis of AD remains poorly understood. Importantly, its neurodegenerative perspective has been challenged towards a more "systemic" view. Amyloid-β (Aβ) and hyperphosphorylated Tau protein (P-Tau) (the main AD neuropathological features) affect and are affected by peripheral and brain insulin signalling dysfunction, leading to glucose dysmetabolism, synaptic loss and AD-related cognitive deficits...
February 20, 2018: Neuropharmacology
https://www.readbyqxmd.com/read/29430497/evaluation-of-bone-mineral-density-in-perimenopausal-period
#7
Zhaleh Shariati-Sarabi, Hamid Etemad Rezaie, Nasrin Milani, Farnaz Etemad Rezaie, Ali Etemad Rezaie
Background: The menopausal transition called perimenopause, happens after the reproductive years, and is specified with irregular menstrual cycles, perimenopause symptoms and hormonal changes. Women going through peri menopausal period are vulnerable to bone loss . Osteoporosis is one of the most common debilitating metabolic bone diseases, especially in the women almost around 50 years. This study was intended to evaluate the prevalence of osteopenia/osteoporosis amongst asymptomatic individuals during the menopause transition period...
January 2018: Archives of Bone and Joint Surgery
https://www.readbyqxmd.com/read/29391675/use-of-hysteroscopy-in-abnormal-uterine-bleeding-an-edge-over-histopathological-examination
#8
Parul Sinha, Nidhi Yadav, Uma Gupta
Purpose of the Study: To assess the efficacy of hysteroscopy in diagnosis of AUB. Method: A total of 56 women in reproductive and peri-menopausal age group (20-50 years) with complaints of abnormal uterine bleeding were enrolled in the study. All the patients underwent hysteroscopic examination followed by biopsy/histopathological evaluation. Hysteroscopic findings were compared against histopathological findings. Sensitivity, specificity, PPV, NPV and accuracy of hysteroscopy were calculated...
February 2018: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/29391065/comparison-of-lipid-profiles-and-inflammation-in-pre-and-post-menopausal-women-with-cerebral-infarction-and-the-role-of-atorvastatin-in-such-populations
#9
Jinhong Zhang, Hong Wang, Shuying Yang, Xiufen Wang
BACKGROUND: The risks of atherosclerotic cardiovascular and cerebrovascular diseases in women rapidly increase with age in post-menopausal women. We aimed to investigate the lipid profiles in peri-menopausal women with cerebral infarction and to explore the effects of atorvastatin intervention. METHODS: We collected women aged 40-60 with cerebral infarction between January 2013 and December 2016. Atorvastatin was applied for 6 months in all included patients. Blood lipid profiles, serum pro-inflammation cytokines, intracranial plaque and NIH stroke scale (NIHSS) scores were evaluated before and after atorvastatin treatment...
February 2, 2018: Lipids in Health and Disease
https://www.readbyqxmd.com/read/29390893/association-of-body-composition-with-menopausal-symptoms-in-peri-menopausal-women
#10
Y Zhou, Y Zheng, C Li, J Hu, Y Zhou, L Geng, M Tao
OBJECTIVE: To explore the correlation of body composition with the severity of menopausal symptoms, as well as each classic menopausal symptom. METHODS: A total of 758 (peri-)menopausal women were recruited (aged from 40 to 67 years) from the Menopause Clinic in the Shanghai Sixth People's Hospital. Different regions of fat mass, lean mass and fat-free mass were measured by bioelectrical impedance analysis, while menopausal symptoms were evaluated by valid modified Kupperman's index (KMI) in the Chinese version...
April 2018: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/29285838/vasomotor-urogenital-psychological-and-somatic-symptoms-in-association-with-cyp1b1-polymorphisms-in-slovak-women-of-different-menopausal-status
#11
Veronika Candráková Čerňanová, Zuzana Danková, Lenka Vorobeľová, Marta Cvíčelová, Daniela Siváková
OBJECTIVES: The aim of this study was to examine if the Arg48Gly, Ala119Ser, Leu432Val, and Asn453Ser polymorphisms in the CYP1B1 estrogen-metabolizing gene are associated with menopausal symptom experience in healthy Slovak women aged 40-60 years. We also investigated the possible association of other factors with menopausal symptoms, including health status, physical activity, reproductive history, psychological status, and smoking. METHODS: The total sample consisted of 367 women (mean age 49...
December 29, 2017: American Journal of Human Biology: the Official Journal of the Human Biology Council
https://www.readbyqxmd.com/read/29250686/ovarian-strumal-carcinoid-case-report
#12
Delia Gabriela Ciobanu Apostol, Tudor Andrei BuŢureanu, Demetra Gabriela Socolov, Daniela Claudia Scripcaru, Oana LuminiŢa Rosin, Ludmila Lozneanu
Strumal carcinoid represents a rare form of ovarian teratoma, consisting of both thyroid tissue and carcinoid structures. The carcinoid component is a well-differentiated neuroendocrine tumor with excellent prognosis. Strumal carcinoid tumors are commonly found in peri-menopausal women who are not usually interested in preserving their fertility and who are thus open to radical surgical treatment. In this report, we present a 24-year-old, nulliparous patient with strumal carcinoid, confirmed by histopathology and a large panel of immunohistochemistry (IHC) markers, who wished to preserve her fertility...
2017: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/29231589/-effects-of-moxibustion-at-shenshu-bl-23-on-level-of-sex-hormones-and-amh-in-sub-health-peri-menopausal-women
#13
Jie Shen, Meihong Shen, Zhongren Li, Rongli Zhang, Xia Li, Bingwei Ai
OBJECTIVE: To compare the effects between moxibustion at Shenshu (BL 23) and oral administration of Vitamin E on quality of life and mechanism in sub-health perimenopausal women, aiming to provide clinical evidence of moxibustion for health care of sub-health female. METHODS: Sixty participants were randomly divided into a moxibustion group and a medication group, 30 cases in each one. The volunteers in the moxibustion group were treated with mild moxibustion at bilateral Shenshu (BL 23) for 15 min, once a day; five treatments were considered as a course of treatment, and totally 4 courses were given with an interval of 2 days between courses...
April 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29224248/is-there-a-pathogenetic-link-between-frontal-fibrosing-alopecia-androgenetic-alopecia-and-fibrosing-alopecia-in-a-pattern-distribution
#14
LETTER
A C Katoulis, K Diamanti, D Sgouros, A I Liakou, E Bozi, G Avgerinou, I Panayiotides, D Rigopoulos
No abstract text is available yet for this article.
December 10, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29170148/a-group-of-500-women-whose-health-may-depart-notably-from-the-norm-protocol-for-a-cross-sectional-survey
#15
Christoph Schnelle, Eunice J Minford, Vanessa McHardy, Jane Keep
BACKGROUND: Longitudinal studies of women's health often seek to identify predictors of good health. Research has shown that following simple guidelines can halve women's mortality. The ongoing Australian Longitudinal Study of Women's Health (ALSWH) shows that Australian women are getting better at reducing their smoking and alcohol use, and are generally diligent about attending recommended health screenings, but are becoming less successful at dealing with obesity. There are communities of women who live unusually healthy lives (Rosetans, Seventh-Day Adventists, traditional Japanese women), but their lifestyles are unlikely to be adopted widely...
November 23, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/29076687/symptoms-of-menopause-in-peri-and-postmenopausal-women-and-their-attitude-towards-them
#16
Kausar Inayat, Nargis Danish, Lubna Hassan
BACKGROUND: The climacteric or perimenopause is the transitional phase during which reproductive function ceases. The average age of the menopause is 51.4 years with a duration of two years. Symptomatology include: vasomotor, psychological, urogenital/sexual, skin, menstrual irregularities and others. The objective was to study the attitude of these women towards menopause. METHODS: In this cross-sectional study, 500 women were included. RESULTS: Palpitations and headaches were found in 30% and 32% respectively in perimenopausal women compared to 16% and 20% in postmenopausal women...
July 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/29071997/-effect-of-electroacupuncture-on-hypothalamus-pituitary-ovary-hpo-axis-in-rats-with-peri-menopausal-depression
#17
Xi-Rong Jiang, Lu Ren, Chun-Ri Li
OBJECTIVE: To observe the effect of electroacupuncture (EA) on the hormones derived from the hypothalamus-pituitary-ovary (HPO) axis, so as to explore the neuroendocrine mechanism induced by EA on rats with perimenopausal depression disorder. METHODS: Sixty female sprague-dawley rats were randomly divided into blank control group, model group, sham-operation (sham) group, clomipramine group, and electroacupuncture (EA) group, with 12 rats in each group. Perimenopausal depression model was established by bilateral ovariectomy combined with chronic unpredictable stimulation...
February 25, 2017: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29061416/prevalence-of-depression-among-middle-aged-women-in-the-rural-area-of-kerala
#18
Archana Ps, Soumitra Das, Sairu Philip, Rekha Rachel Philip, Jose Joseph, Varghese P Punnoose, Deepthilal Pachan Lalithambika
AIMS: The aim of this study was to determine the prevalence of Depression among women aged 40-60 years in the rural area of Kerala using Patient Health Questionnaire 9 (PHQ-9). SETTINGS AND DESIGN: Ambalappuzha is an area of rural background under the District of Alappuzha. The study was conducted by Preventive and Social Medicine department of Govt. T. D. Medical College, Kerala in collaboration with the department of Psychiatry with the help of Ambalappuzha health centre...
October 2017: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/29044004/research-on-the-influence-of-bilateral-oophorectomy-on-the-bmd-body-components-and-sex-hormone-of-women-during-the-perimenopause
#19
HaiLi Wang, Chuchu Wang, Lei Sun, Shiyuan Zhou, Fengyu Wang
To investigate the effect of bilateral oophorectomy on bone mineral density, body composition and sex hormone of peri-menopause women. 33 cases of peri-menopause women patients performed bilateral oophorectomy were chosen from xxx gynaecology and obstetrics department of xxx hospital from January 1st,2014 to Dec31th, 2014. And the 33 cases were taken as ovariectomy group. 35 women who were the naturally postmenopausal after menopause collected in clinic and in the same period with the patients of ovariectomy group were taken in control group...
July 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29029258/acupuncture-improves-peri-menopausal-insomnia-a-randomized-controlled-trial
#20
RANDOMIZED CONTROLLED TRIAL
Cong Fu, Na Zhao, Zhen Liu, Lu-Hua Yuan, Chen Xie, Wen-Jia Yang, Xin-Tong Yu, Huan Yu, Yun-Fei Chen
Study Objectives: To evaluate the short-term efficacy of acupuncture for the treatment of peri-menopausal insomnia (PMI). Methods: Design: A randomized, participant-blind, placebo-controlled trial consisted of the acupuncture group (n = 38) and placebo-acupuncture group (n = 38). Setting: A tertiary teaching and general hospital. Participants: 76 peri-menopausal women with insomnia disorder based on the International Classification of Sleep Disorders, Third Edition...
November 1, 2017: Sleep
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