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https://www.readbyqxmd.com/read/27845510/outcomes-of-monopolar-versus-bipolar-endometrial-ablation-on-uterine-bleeding-and-psychophysical-wellbeing
#1
Pasquale De Franciscis, Flavio Grauso, Luigi Cobellis, Enrico M Messalli, Gaspare Cucinella, Antonino Perino, Nicola Colacurci, Marco Torella
PURPOSE: to compare outcomes of endometrial ablation with monopolar versus bipolar resection on uterine bleeding and psychophysical wellbeing. METHODS: In a prospective randomized study, 100 peri-menopausal patients, without desire of pregnancy and with no response to pharmacological treatment, underwent endometrial ablation from 2012 to 2014. They were randomly divided in two groups: 50 patients treated with monopolar electrode resection loop (group A) and 50 patients treated with bipolar electrode resection loop (group B)...
November 15, 2016: Minerva Ginecologica
https://www.readbyqxmd.com/read/27821168/associations-of-proteins-relevant-to-mapk-signaling-pathway-p38mapk-1-hif-1-and-ho-1-with-coronary-lesion-characteristics-and-prognosis-of-peri-menopausal-women
#2
Liqiu Yan, Xufen Cao, Saitian Zeng, Zhe Li, Zheng Lian, Jiawang Wang, Fengfeng Lv, Yunfei Wang, Yanshen Li
BACKGROUND: The present study was intended to explore whether three proteins within MAPK signaling pathway (i.e. p38MAPK-1, HIF-1 and HO-1) were correlated with peri-menopausal women's coronary lesion features and prognosis. METHODS: Altogether 1449 peri-menopausal women were divided into non-coronary artery disease (CAD) group (n = 860) and CAD group (n = 589), including 167 pre-menopausal CAD populations and 422 post-menopausal CAD populations. General information about CAD risk parameters were gathered, including age, family history of CAD or hypertension or diabetes mellitus, bilirubin, cholesterol, triglyceride, high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C) and so on...
November 8, 2016: Lipids in Health and Disease
https://www.readbyqxmd.com/read/27621257/the-interlace-study-design-data-harmonization-and-characteristics-across-20-studies-on-women-s-health
#3
Gita D Mishra, Hsin-Fang Chung, Nirmala Pandeya, Annette J Dobson, Lee Jones, Nancy E Avis, Sybil L Crawford, Ellen B Gold, Daniel Brown, Lynette L Sievert, Eric Brunner, Janet E Cade, Victoria J Burley, Darren C Greenwood, Graham G Giles, Fiona Bruinsma, Alissa Goodman, Kunihiko Hayashi, Jung Su Lee, Hideki Mizunuma, Diana Kuh, Rachel Cooper, Rebecca Hardy, Carla Makhlouf Obermeyer, Kathryn A Lee, Mette Kildevæld Simonsen, Toyoko Yoshizawa, Nancy F Woods, Ellen S Mitchell, Mark Hamer, Panayotes Demakakos, Sven Sandin, Hans-Olov Adami, Elisabete Weiderpass, Debra Anderson
OBJECTIVES: The International Collaboration for a Life Course Approach to Reproductive Health and Chronic Disease Events (InterLACE) project is a global research collaboration that aims to advance understanding of women's reproductive health in relation to chronic disease risk by pooling individual participant data from several cohort and cross-sectional studies. The aim of this paper is to describe the characteristics of contributing studies and to present the distribution of demographic and reproductive factors and chronic disease outcomes in InterLACE...
October 2016: Maturitas
https://www.readbyqxmd.com/read/27506466/menopause-induced-uterine-epithelium-atrophy-results-from-arachidonic-acid-prostaglandin-e2-axis-inhibition-mediated-autophagic-cell-death
#4
Shengtao Zhou, Linjie Zhao, Tao Yi, Yuquan Wei, Xia Zhao
Women experience menopause later in life. Menopause is characterized by dramatically decreased circulating estrogen level secondary to loss of ovarian function and atrophic state of genital organs. However, the molecular mechanisms for this process are not fully understood. In this study, we aimed to investigate the potential molecular mechanisms that underlie menopause-induced uterine endometrial atrophy. Our data showed that autophagy was activated in the uterine epithelial cells of both ovariectomized rats and peri-menopausal females...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27294327/triglyceride-levels-and-fracture-risk-in-midlife-women-study-of-women-s-health-across-the-nation-swan
#5
Po-Yin Chang, Ellen B Gold, Jane A Cauley, Wesley O Johnson, Carrie Karvonen-Gutierrez, Elizabeth A Jackson, Kristine M Ruppert, Jennifer S Lee
CONTEXT: Unfavorable lipid levels contribute to cardiovascular disease and may also harm bone health. OBJECTIVE: Our objective was to investigate relationships between fasting plasma lipid levels and incident fracture in midlife women undergoing the menopausal transition. DESIGN AND SETTING: This was a 13-year prospective, longitudinal study of multiethnic women in five US communities, with near-annual assessments. PARTICIPANTS: At baseline, 2062 premenopausal or early perimenopausal women who had no history of fracture were included...
September 2016: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27265705/does-menopausal-transition-really-influence-mental-health-findings-from-the-prospective-long-term-zurich-study
#6
Wulf Rössler, Vladeta Ajdacic-Gross, Anita Riecher-Rössler, Jules Angst, Michael P Hengartner
In the prospective long-term Zurich study, we re-examined the hypothesized association between mental health problems in women and the transition through menopausal stages. One hundred sixty-eight women from a population-based Swiss community cohort were prospectively followed up from age 21 to 50. At age 50, the occurrence of hot flushes/night sweats and sleep disturbances was significantly more frequent in peri- and post-menopausal women. Irritability/nervousness was increased only in peri-menopausal women, but that association was accounted for by neuroticism trait scores at age 30...
June 2016: World Psychiatry: Official Journal of the World Psychiatric Association (WPA)
https://www.readbyqxmd.com/read/27261985/osteopathic-manipulative-treatment-in-gynecology-and-obstetrics-a-systematic-review
#7
REVIEW
Nuria Ruffini, Giandomenico D'Alessandro, Lucia Cardinali, Franco Frondaroli, Francesco Cerritelli
OBJECTIVE: The aim of the review was to evaluate the effects of the osteopathic manipulative treatment (OMT) on women with gynaecological and obstetric disorders. MATERIALS AND METHODS: An extensive search from inception to April 2014 was conducted on MEDLINE, Embase, the Cochrane library using MeSH and free terms. Clinical studies investigating the effect of OMT in gynaecologic and obstetric conditions were included as well as unpublished works. Reviews and personal contributions were excluded...
June 2016: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/27139906/vitamin-e-homologues-%C3%AE-and-%C3%AE-tocopherol-are-not-associated-with-bone-turnover-markers-or-bone-mineral-density-in-peri-menopausal-and-post-menopausal-women
#8
T C Yang, G G Duthie, L S Aucott, H M Macdonald
UNLABELLED: In a large cohort of older women, we investigated the relationships that different forms of vitamin E may have with bone turnover markers and bone mineral density (BMD). We found a suggestive positive association between serum alpha-tocopherol and BMD at the femoral neck, but no other clinically relevant observations. INTRODUCTION: Vitamin E has anti-oxidant and anti-inflammatory properties hypothesized to benefit bone, but limited studies exist regarding its homologues...
July 2016: Osteoporosis International
https://www.readbyqxmd.com/read/27042516/profile-of-breast-diseases-in-post-pubertal-women-assessed-by-clinical-breast-examination-a-community-based-study-in-rural-pondicherry
#9
Kavasseri L Janaki, Narayanasamy Subbaraju Kannan, M Palaniappan, Partha Nandi
INTRODUCTION: Breast diseases in women, whether benign or malignant, are very commonly encountered. Benign diseases are under reported and cancer is one of the leading causes of mortality in women. This study was undertaken with an aim to study the profile of various breast disease in the community. MATERIALS AND METHODS: In this observational study all the post pubertal women residing in the selected village (n=1000) were included. The study was done from September 2013 to August 2015...
February 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/26993224/effects-of-estrogen-on-cerebrovascular-function-age-dependent-shifts-from-beneficial-to-detrimental-in-small-cerebral-arteries-of-the-rat
#10
Rachel R Deer, John N Stallone
In the present study, interactions of age and estrogen in the modulation of cerebrovascular function were examined in small arteries <150 μM. The hypothesis tested was that age enhances deleterious effects of exogenous estrogen by augmenting constrictor prostanoid (CP)-potentiated reactivity of the female (F) cerebrovasculature. F Sprague-Dawley rats approximating key stages of "hormonal aging" in humans were studied: perimenopausal (mature multi-gravid, MA, cyclic, 5-6 mo of age) and postmenopausal (reproductively senescent, RS, acyclic 10-12 mo of age)...
May 15, 2016: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/26951639/reducing-inappropriate-testing-in-the-diagnosis-of-the-menopause-and-peri-menopause
#11
Jac Williams, Heather Currie, Adele Foster, Julia Anderson
The menopause should be diagnosed based on age, menstrual history and clinical symptoms, and as such, follicle stimulating hormone testing may be considered inappropriate when diagnosing the menopause or peri-menopause in women aged 45 and over. As part of a demand optimisation programme, the number of follicle stimulating hormone tests requested to diagnose the menopause in this age group was quantified and educational interventions were implemented to reduce inappropriate testing. The number of follicle stimulating hormone tests requested to diagnose the menopause in women aged 45 and over was successfully and sustainably reduced...
September 2016: Post Reproductive Health
https://www.readbyqxmd.com/read/26940232/is-menopausal-status-related-to-women-s-attitudes-toward-menopause-and-aging
#12
Doyel Dasgupta, Subho Roy
The objective of this study was to explore the relationship between menopausal status and attitudes toward menopause and aging. We identified 1400 Bengali Hindu women aged 40-55 years (early peri-menopausal n = 445; late peri-menopausal n = 240; early postmenopausal n = 285; late postmenopausal n = 430) from West Bengal, India. Information on attitudes toward menopause and aging was collected from March 2009 to July 2012 using ten agree/disagree statements, of which three were positive, four were negative, and the rest were neutral...
March 3, 2016: Women & Health
https://www.readbyqxmd.com/read/26929531/burning-mouth-syndrome-current-concepts
#13
REVIEW
Cibele Nasri-Heir, Julyana Gomes Zagury, Davis Thomas, Sowmya Ananthan
Burning mouth syndrome (BMS) is a chronic pain condition. It has been described by the International Headache Society as "an intra-oral burning or dysesthetic sensation, recurring daily for more than 2 h/day for more than 3 months, without clinically evident causative lesions." BMS is frequently seen in women in the peri-menopausal and menopausal age group in an average female/male ratio of 7:1. The site most commonly affected is the anterior two-thirds of the tongue. The patient may also report taste alterations and oral dryness along with the burning...
October 2015: Journal of Indian Prosthodontic Society
https://www.readbyqxmd.com/read/26847310/a-rare-case-of-intra-endometrial-leiomyoma-of-uterus-simulating-degenerated-submucosal-leiomyoma-accompanied-by-a-large-sertoli-leydig-cell-tumor
#14
Kyungah Jeong, Sa Ra Lee, Sanghui Park
A 50-year-old peri-menopausal woman presented with hard palpable mass on her lower abdomen and anemia from heavy menstrual bleeding. Ultrasonography showed a 13×12 cm sized hypoechoic solid mass in pelvis and a 2.5×2 cm hypoechoic cystic mass in uterine endometrium. Abdomino-pelvic computed tomography revealed a hypodense pelvic mass without enhancement, suggesting a leiomyoma of intraligamentary type or sex cord tumor of right ovary with submucosal myoma of uterus. Laparoscopy revealed a large Sertoli-Leydig cell tumor of right ovary with a very rare entity of intra-endometrial uterine leiomyoma accompanied by adenomyosis...
March 2016: Yonsei Medical Journal
https://www.readbyqxmd.com/read/26596902/psychometric-attributes-of-the-cervantes-short-form-questionnaire-for-measuring-health-related-quality-of-life-in-menopausal-women
#15
Pluvio J Coronado, Rafael Sánchez-Borrego, Miguel A Ruiz, Laura Baquedano, Sonia Sánchez, Cristina Argudo, Mariela Fernández-Abellán, Silvia González, Eva Iglesias, Jackie Calleja, Jesus Presa, Alfonso Duque, Fernando Ruiz, Borja Otero, Javier Rejas
OBJECTIVE: To analyse the psychometric properties of the Cervantes scale short-form (SF) in the peri- and post-menopausal periods. METHODS: Outpatients women 45-65 years with menstrual problems associated with the climacteric syndrome were analysed. Original and SF versions of the Cervantes scale were administered along with the EuroQol-5D (EQ-5D) and work productivity and activity impairment questionnaire (WPAI) scales. Conceptual model, burden of administration, feasibility, reliability, criteria validity and construct validity were assessed...
February 2016: Maturitas
https://www.readbyqxmd.com/read/26512337/sleep-disorders-in-postmenopausal-women
#16
Shazia Jehan, Alina Masters-Isarilov, Idoko Salifu, Ferdinand Zizi, Girardin Jean-Louis, Seithikurippu R Pandi-Perumal, Ravi Gupta, Amnon Brzezinski, Samy I McFarlane
One of the core symptoms of the menopausal transition is sleep disturbance. Peri-menopausal women often complain of difficulties initiating and/or maintaining sleep with frequent nocturnal and early morning awakenings. Factors that may play a role in this type of insomnia include vasomotor symptoms, changing reproductive hormone levels, circadian rhythm abnormalities, mood disorders, coexistent medical conditions, and lifestyle. Other common sleep problems in this age group, such as obstructive sleep apnea and restless leg syndrome, can also worsen the sleep quality...
August 2015: Journal of Sleep Disorders & Therapy
https://www.readbyqxmd.com/read/26380958/stress-urinary-incontinence-and-endogenous-sex-steroids-in-postmenopausal-women
#17
Areti Augoulea, Dimos Sioutis, Demetrios Rizos, Constantinos Panoulis, Nikolaos Triantafyllou, Eleni Armeni, Efthymios Deligeoroglou, Charalambos Chrelias, Maria Creatsa, Angelos Liapis, Irene Lambrinoudaki
AIMS: Urinary incontinence in general is a major cause of quality of life impairment, morbidity and hospitalization. Its onset is strongly linked to the menopause. Our study aimed to elucidate the possible relationship between endogenous circulating estrogens and the onset and development of stress urinary incontinence (SUI). METHODS: One hundred and thirty eight peri- and postmenopausal women with SUI were matched 1:1 with continent women based on age and BMI. Morning fasting blood samples were drawn from all subjects for assessment of estradiol (E2), FSH, LH, Testosterone, Δ4-Androstendione (Δ4Α), DHEAS, prolactin, SBHG as well as a biochemical profile (glucose, insulin, triglycerides, cholesterol, HDL, LDL, ApoA1, ApoB)...
September 18, 2015: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/26327893/clinical-implications-of-vitamin-d-deficiency
#18
Beata Matyjaszek-Matuszek, Monika Lenart-Lipińska, Ewa Woźniakowska
Vitamin D deficiency is a common medical problem worldwide and its prevalence rises along with latitude, obesity, sedentary lifestyle, limited sunlight exposure and aging. A great body of evidence has shown that patients with vitamin D deficiency have increased cardiovascular risks and total mortality. Conversely, the presence of comorbidities progressive with age such as abdominal obesity, insulin resistance, type 2 diabetes and hypertension places the patients at an increased risk of vitamin D deficiency...
June 2015: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/26327865/menopausal-hormone-therapy-and-venous-thromboembolism
#19
Małgorzata Bińkowska
Menopausal hormone therapy (MHT) is the most effective method of treating vasomotor symptoms and other climacteric symptoms related to estrogen deficiency in peri- and postmenopausal period. In addition to estrogen replacement, women with preserved uterus require the addition of progestagen in order to ensure endometrial safety. One of rare but severe complications of MHT is venous thromboembolism (VTE). The incidence of VTE rises in parallel to women's age and body weight. The condition is also linked to hereditary and acquired risk factors...
October 2014: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/26313461/a-prognostic-analysis-of-male-breast-cancer-mbc-compared-with-post-menopausal-female-breast-cancer-fbc
#20
Xing-Fei Yu, Hong-Jian Yang, Yang Yu, De-Hong Zou, Lu-Lu Miao
BACKGROUND: Male breast cancer (MBC) is known to be rare compared with female breast cancer (FBC) and to account for only 1% of all breast cancers. To date, male patients diagnosed with breast cancer are normally treated based on the guidelines for FBC. Specifically, studies have found that diagnosing and treating MBC patients under the guidelines for the treatment of post-menopausal FBC are more favorable than are those of pre/peri-menopausal FBC from a physiological perspective because MBC and post-menopausal FBC patients show high estrogen receptor (ER) expression in the tumor and low estrogen expression in the body...
2015: PloS One
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