keyword
MENU ▼
Read by QxMD icon Read
search

Neonate, preterm,term

keyword
https://www.readbyqxmd.com/read/28922852/magnesium-sulfate-prevents-neurochemical-and-long-term-behavioral-consequences-of-neonatal-excitotoxic-lesions-comparison-between-male-and-female-mice
#1
Ismaël Daher, Bérénice Le Dieu-Lugon, Nathalie Dourmap, Matthieu Lecuyer, Lauriane Ramet, Cathy Gomila, Jérôme Ausseil, Stéphane Marret, Philippe Leroux, Vincent Roy, Salah El Mestikawy, Stéphanie Daumas, Bruno Gonzalez, Isabelle Leroux-Nicollet, Carine Cleren
Magnesium sulfate (MgSO4) administration to mothers at risk of preterm delivery is proposed as a neuroprotective strategy against neurological alterations such as cerebral palsy in newborns. However, long-term beneficial or adverse effects of MgSO4 and sex-specific sensitivity remain to be investigated. We conducted behavioral and neurochemical studies of MgSO4 effects in males and females, from the perinatal period to adolescence in a mouse model of cerebral neonatal lesion. The lesion was produced in 5-day-old (P5) pups by ibotenate intracortical injection...
October 1, 2017: Journal of Neuropathology and Experimental Neurology
https://www.readbyqxmd.com/read/28919619/comparison-of-serum-bilirubin-with-transcutaneous-bilirubinometry-in-late-preterm-and-term-newborn
#2
N Nahar, M A Mannan, A C Dey, F Ahmed, K A Khan, I Jahan, S K Dey, M Shahidullah
Neonatal jaundice or hyperbilirubinemia is a common occurrence in newborns. It can progress to develop kernicterus unless intervention is initiated. Severity and decision for management are usually based on serum bilirubin which needs blood sampling. Transcutaneous bilirubin measurement is a noninvasive technique and correlates closely with serum bilirubin. This Cross sectional study was done in the Department of Neonatology, Bangabandhu Sheikh Mujib Medical University from March 2013 to August 2014 to evaluate the transcutaneous bilirubin in comparison to serum bilirubin...
July 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28919465/uridine-treatment-protects-against-neonatal-brain-damage-and-long-term-cognitive-deficits-caused-by-hyperoxia
#3
Bulent Goren, Aysen Cakir, Cansu Sevinc, Sema Serter Kocoglu, Busra Ocalan, Ceren Oy, Zehra Minbay, Nevzat Kahveci, Tulin Alkan, Mehmet Cansev
Exposure to excessive oxygen in survivors of preterm birth is one of the factors that underlie the adverse neurological outcome in later life. Various pathological changes including enhanced apoptotic activity, oxidative stress and inflammation as well as decreased neuronal survival has been demonstrated in animal models of neonatal hyperoxia. The aim of the present study was to investigate the effect of administering uridine, an anti-apoptotic agent, on cellular, molecular and behavioral consequences of hyperoxia-induced brain damage in a neonatal rat model...
September 15, 2017: Brain Research
https://www.readbyqxmd.com/read/28917582/preterm-pre-eclampsia-what-every-neonatologist-should-know
#4
REVIEW
Lisa Story, Lucy C Chappell
Although pre-eclampsia affects 5-10% of pregnancies globally and is responsible for substantial maternal and perinatal morbidity and mortality, currently there is no cure other than delivery of the baby. Predictive screening tests based on clinical risk factors, with or without the addition of biomarkers and imaging, have been developed, but adoption into clinical practice is limited by suboptimal test performance. Once established pre-eclampsia is diagnosed, a woman is usually managed expectantly prior to 37weeks' gestation to reduce perinatal morbidity and mortality associated with iatrogenic prematurity until maternal or fetal triggers for delivery mean that risks of pregnancy prolongation outweigh the benefits...
September 13, 2017: Early Human Development
https://www.readbyqxmd.com/read/28915231/postnatal-polyunsaturated-fatty-acids-associated-with-larger-preterm-brain-tissue-volumes-and-better-outcomes
#5
Daphne Kamino, Colin Studholme, Mengyuan Liu, Vann Chau, Steven P Miller, Anne Synnes, Elizabeth E Rogers, A James Barkovich, Donna M Ferriero, Rollin Brant, Emily W Y Tam
BACKGROUND: Human studies investigating the link between postnatal polyunsaturated fatty acids and preterm brain growth are limited, despite emerging evidence of potential effects on outcomes. METHODS: Sixty preterm neonates <32 weeks gestational age with MRI scanning at near-birth and near-term age were assessed for brain tissue volumes including cortical grey matter, white matter, deep grey matter, cerebellum, brainstem and ventricular cerebrospinal fluid. Red blood cell fatty acid content was evaluated within 1 week of each MRI scan...
September 15, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28913327/in-vivo-evaluation-of-the-acute-pulmonary-response-to-poractant-alfa-and-bovactant-treatments-in-lung-lavaged-adult-rabbits-and-in-preterm-lambs-with-respiratory-distress-syndrome
#6
Francesca Ricci, Fabrizio Salomone, Elke Kuypers, Daan Ophelders, Maria Nikiforou, Monique Willems, Tobias Krieger, Xabier Murgia, Matthias Hütten, Boris W Kramer, Federico Bianco
BACKGROUND: Poractant alfa (Curosurf(®)) and Bovactant (Alveofact(®)) are two animal-derived pulmonary surfactants preparations approved for the treatment of neonatal respiratory distress syndrome (nRDS). They differ in their source, composition, pharmaceutical form, and clinical dose. How much these differences affect the acute pulmonary response to treatment is unknown. OBJECTIVES: Comparing these two surfactant preparations in two different animal models of respiratory distress focusing on the short-term response to treatment...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28913132/the-incidence-risk-factors-and-mortality-of-preterm-neonates-a-prospective-study-from-jordan-2012-2013
#7
Nadin M Abdel Razeq, Yousef S Khader, Anwar M Batieha
OBJECTIVE: To explore the incidence of preterm delivery, maternal risk factors for having a preterm neonate, and preterm neonates' mortality in Jordan. MATERIALS AND METHODS: A cross-sectional population-based design was applied. Socio-demographic, perinatal, delivery risk factors, and survival information were gathered in pre- and post-hospital discharge interviews with 21075 women who gave birth to live neonates at ≥20 weeks of gestation in 18 hospitals in Jordan...
March 2017: Turk J Obstet Gynecol
https://www.readbyqxmd.com/read/28913118/the-course-and-outcomes-of-complicated-gallstone-disease-in-pregnancy-experience-of-a-tertiary-center
#8
Mehmet İlhan, Gülşah İlhan, Ali Fuat Kaan Gök, Kayıhan Günay, Cemalettin Ertekin
OBJECTIVE: To evaluate the course and outcomes of pregnant patients with complicated gallstone disease and to reveal the experience of a tertiary center. MATERIALS AND METHODS: The records of 92.567 patients were evaluated using searches for diagnoses with the terms of pregnant, pregnancy, gallstone, cholecystitis, cholangitis, choledocholithiasis, pancreatitis, and endoscopic retrograde cholangiopancreatography in pregnancy in the hospital database. Patients' age, week of gestation, parity, body mass index, definitive diagnosis, attack episodes, treatment modalities, and obstetric and neonatal complications were evaluated...
December 2016: Turk J Obstet Gynecol
https://www.readbyqxmd.com/read/28901786/effect-of-gestational-age-on-the-epidemiology-of-late-onset-sepsis-in-neonatal-intensive-care-units-a-review
#9
Elsa de Palma Afonso, Stijn Blot
Neonatal sepsis is a major cause of morbidity and mortality. Late-onset sepsis affects a significant percentage of infants admitted to the neonatal intensive care unit (NICU). Most affected newborns are preterm or low birth weight, but late-onset sepsis also affects late preterm and term infants. Understanding how gestational age affects the epidemiology of late-onset sepsis can be of use when defining strategies for its prevention and clinical management in NICU. Areas covered: Available evidence suggests the incidence and mortality of late-onset sepsis is higher in preterm and VLBW infants, but pathogen distribution and risk exposure is similar across all infants admitted to NICU...
September 13, 2017: Expert Review of Anti-infective Therapy
https://www.readbyqxmd.com/read/28899617/better-medicines-for-neonates-improving-medicine-development-testing-and-prescribing
#10
Karel Allegaert
Pharmacotherapy is a powerful tool to improve the outcome of neonates. Unfortunately, the potential health impact of pharmacotherapy in neonates remains underexplored. This necessitates a structured approach to go beyond the current practice of trial and error, reflected in off-label prescription. The existing regulatory framework hereby provides a structure to reflect about aspects like pharmacokinetic models for dose selection and outcome assessment, including long-term safety. Future medicine development should also be driven by neonatal needs, diseases and pathophysiology, since surfactant is the latest product developed for preterm neonates...
September 9, 2017: Early Human Development
https://www.readbyqxmd.com/read/28898404/high-versus-standard-volume-enteral-feeds-to-promote-growth-in-preterm-or-low-birth-weight-infants
#11
REVIEW
Thangaraj Abiramalatha, Niranjan Thomas, Vijay Gupta, Anand Viswanathan, William McGuire
BACKGROUND: Breast milk alone, given at standard recommended volumes (150 to 180 mL/kg/d), is not adequate to meet the protein, energy, and other nutrient requirements of growing preterm or low birth weight infants. One strategy that may be used to address these potential nutrient deficits is to give infants enteral feeds in excess of 200 mL/kg/d ('high-volume' feeds). This approach may increase nutrient uptake and growth rates, but concerns include that high-volume enteral feeds may cause feed intolerance, gastro-oesophageal reflux, aspiration pneumonia, necrotising enterocolitis, or complications related to fluid overload, including patent ductus arteriosus and bronchopulmonary dysplasia...
September 12, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28892882/circulating-protein-carbonyls-antioxidant-enzymes-and-related-trace-minerals-among-preterms-with-respiratory-distress-syndrome
#12
Ahmed El-Abd Ahmed, Eman Ahmed Abd-Elmawgood, Mohammed H Hassan
INTRODUCTION: Information about oxidative stress in preterms with Respiratory Distress Syndrome (RDS) is defective, so various researches in this area are required, which may open new roads in understanding the pathogenesis of the disease, hence provide additional helpful therapeutic approaches. AIM: To assess and compare the plasma level of protein carbonyls as a marker for oxidant status and the antioxidant enzymes; Superoxide Dismutase (SOD) and Glutathione Peroxidase (GPx) and the related trace minerals in the form of Copper (Cu), Zinc (Zn) and Selenium (Se) as markers for antioxidant status, in preterms with and without RDS...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28889777/assessment-of-neonatal-adrenal-size-using-high-resolution-2d-ultrasound-and-its-correlation-with-birth-demographics-clinical-outcomes
#13
Tijen Karsli, Diana Strickland, Jeffrey Livingston, Qiang Wu, Maroun J Mhanna, Prem S Shekhawat
OBJECTIVE: Assessment of adrenal function in a sick neonate remains a challenge in spite of major advances in neonatal care. We used 2D ultrasound of adrenal glands to assess maturity of adrenal glands in extremely preterm infants and sick term and near term infants. STUDY DESIGN: We collected demographics details of 99 mother-infants pairs (24-41 weeks) and obtained 2D ultrasound scans of adrenal glands in first week of life to measure adrenal volume, fetal zone size and adrenal to kidney ratios...
September 10, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28882131/an-evaluation-of-interprofessional-group-antenatal-care-a-prospective-comparative-study
#14
Zoë G Hodgson, Lee Saxell, Julian K Christians
BACKGROUND: Maternal and neonatal outcomes are influenced by the nature of antenatal care. Standard pregnancy care is provided on an individual basis, with one-on-one appointments between a client and family doctor, midwife or obstetrician. A novel, group-based antenatal care delivery model was developed in the United States in the 1990s and is growing in popularity beyond the borders of the USA. The purpose of this study was to evaluate outcomes in clients receiving interprofessional group perinatal care versus interprofessional individual care in a Canadian setting...
September 7, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28882058/role-of-acoustic-radiation-force-impulse-and-shear-wave-velocity-in-prediction-of-preterm-birth-a-prospective-study
#15
Arjit Agarwal, Shubhra Agarwal, Shruti Chandak
Background Preterm birth is one of the important causes of neonatal morbidity where we rely on subjective criteria such as modified Bishop's scoring and contemporary sonographic measurement of cervical length. Acoustic radiation force impulse (ARFI) is a technological advancement in elastography that can be employed in prediction of cervical softening and preterm labor. Purpose To evaluate the role of ARFI technique and shear wave velocity (SWV) estimates as a predictor of preterm birth and its comparison with other clinical and sono-elastographic measures...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28879060/onset-of-human-preterm-and-term-birth-is-related-to-unique-inflammatory-transcriptome-profiles-at-the-maternal-fetal-interface
#16
Radek Bukowski, Yoel Sadovsky, Hani Goodarzi, Heping Zhang, Joseph R Biggio, Michael Varner, Samuel Parry, Feifei Xiao, Sean M Esplin, William Andrews, George R Saade, John V Ilekis, Uma M Reddy, Donald A Baldwin
BACKGROUND: Preterm birth is a main determinant of neonatal mortality and morbidity and a major contributor to the overall mortality and burden of disease. However, research of the preterm birth is hindered by the imprecise definition of the clinical phenotype and complexity of the molecular phenotype due to multiple pregnancy tissue types and molecular processes that may contribute to the preterm birth. Here we comprehensively evaluate the mRNA transcriptome that characterizes preterm and term labor in tissues comprising the pregnancy using precisely phenotyped samples...
2017: PeerJ
https://www.readbyqxmd.com/read/28878297/role-of-nf-%C3%AE%C2%BAb-gata3-in-the-inhibition-of-lysyl-oxidase-by-il-1%C3%AE-in-human-amnion-fibroblasts
#17
Chuyue Zhang, Wangsheng Wang, Chao Liu, Jiangwen Lu, Kang Sun
Preterm premature rupture of membranes (pPROM) accounts for one third of preterm births, a leading cause of neonatal death. Understanding the mechanism of membrane rupture is thus of clinical significance in the prevention of preterm birth. Parturition at both term and preterm is associated with increased abundance of proinflammatory cytokines in the fetal membranes regardless of the presence of infection, which is believed to induce rupture of membranes through activation of the matrix metalloproteinases. It remains unknown whether there are any alternative mechanisms underpinning proinflammatory cytokine-induced rupture of membranes...
September 7, 2017: Immunology and Cell Biology
https://www.readbyqxmd.com/read/28875885/a-review-of-antenatal-corticosteroid-use-in-premature-neonates-in-a-middle-income-country
#18
A Laher, D E Ballot, T Ramdin, T Chirwa
BACKGROUND: Antenatal corticosteroid (ANS) use in premature neonates has become a standard of practice. However, there is low ANS coverage in low- to middle-income countries (LMICs). Recent studies have questioned the efficacy of ANSs in such countries. OBJECTIVE: To review the use of ANSs in preterm neonates at Charlotte Maxeke Johannesburg Academic Hospital (CMJAH), South Africa. METHODS: This was a retrospective observational study of all neonates with a birth weight of 500 - 1 800 g born at CMJAH between 1 January 2013 and 30 June 2016...
August 25, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/28873345/neutrophil-chemotaxis-and-transcriptomics-in-term-and-preterm-neonates
#19
Steven L Raymond, Brittany J Mathias, Tyler J Murphy, Jaimar C Rincon, María Cecilia López, Ricardo Ungaro, Felix Ellett, Julianne Jorgensen, James L Wynn, Henry V Baker, Lyle L Moldawer, Daniel Irimia, Shawn D Larson
Neutrophils play a crucial role in combating life-threatening bacterial infections in neonates. Previous studies investigating neonatal cell function have been limited because of restricted volume sampling. Here, using novel microfluidic approaches, we provide the first description of neutrophil chemotaxis and transcriptomics from whole blood of human term and preterm neonates, as well as young adults. Ex vivo percent cell migration, neutrophil velocity, and directionality to N-formylmethionyl-leucyl-phenylalanine were measured from whole blood using time-lapse imaging of microfluidic chemotaxis...
September 1, 2017: Translational Research: the Journal of Laboratory and Clinical Medicine
https://www.readbyqxmd.com/read/28870134/role-of-massage-therapy-on-reduction-of-neonatal-hyperbilirubinemia-in-term-and-preterm-neonates-a-review-of-clinical-trials
#20
Bhawan Deep Garg, Nandkishor S Kabra, Haribalakrishna Balasubramanian
BACKGROUND: Neonatal hyperbilirubinemia (NNH) is one of the leading causes of admissions in nursery throughout the world. It affects approximately 2.4-15% of neonates during the first 2 weeks of life. AIMS: To evaluate the role of massage therapy for reduction of NNH in both term and preterm neonates. METHOD: The literature search was done for various randomized control trials (RCTs) by searching the Cochrane Library, PubMed, and EMBASE. RESULTS: This review included total of 10 RCTs (2 in preterm neonates and 8 in term neonates) that fulfilled inclusion criteria...
September 4, 2017: Journal of Maternal-fetal & Neonatal Medicine
keyword
keyword
33754
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"