keyword
MENU ▼
Read by QxMD icon Read
search

default mode network

keyword
https://www.readbyqxmd.com/read/29341344/the-medial-temporal-lobe-functional-connectivity-patterns-associated-with-forming-different-mental-representations
#1
Signy Sheldon, Brian Levine
The medial temporal lobes (MTL), and more specifically the hippocampus, are critical for forming mental representations of past experiences - autobiographical memories - and for forming other 'non-experienced' types of mental representations, such as imagined scenarios. How the MTL coordinate with other brain areas to create these different types of representations is not well understood. To address this issue, we performed a task-based functional connectivity analysis on a previously published dataset in which fMRI data were collected as participants created different types of mental representations under three conditions...
January 17, 2018: Hippocampus
https://www.readbyqxmd.com/read/29341320/spatiotemporal-metabolic-and-therapeutic-characterization-of-altered-functional-connectivity-in-major-depressive-disorder
#2
Jintao Sheng, Yuedi Shen, Yanhua Qin, Lei Zhang, Binjia Jiang, Yaoyao Li, Luoyi Xu, Wei Chen, Jinhui Wang
Although imbalanced functional integration has been increasingly reported in major depressive disorder (MDD), there still lacks a general framework to characterize common characteristic and origin shared by the integrative disturbances. Here we examined spatial selectivity, temporal uniqueness, metabolic basis, and therapeutic response of altered functional connectivity (FC) in MDD by analyzing both cross-sectional and longitudinal multimodal functional magnetic resonance imaging data from 35 patients and 34 demographically matched healthy controls...
January 17, 2018: Human Brain Mapping
https://www.readbyqxmd.com/read/29339310/distant-from-input-evidence-of-regions-within-the-default-mode-network-supporting-perceptually-decoupled-and-conceptually-guided-cognition
#3
Charlotte Murphy, Elizabeth Jefferies, Shirley-Ann Rueschemeyer, Mladen Sormaz, Hao-Ting Wang, Daniel S Margulies, Jonathan Smallwood
The default mode network supports a variety of mental operations such as semantic processing, episodic memory retrieval, mental time travel and mind-wandering, yet the commonalities between these functions remains unclear. One possibility is that this system supports cognition that is independent of the immediate environment; alternatively or additionally, it might support higher-order conceptual representations that draw together multiple features. We tested these accounts using a novel paradigm that separately manipulated the availability of perceptual information to guide decision-making and the representational complexity of this information...
January 12, 2018: NeuroImage
https://www.readbyqxmd.com/read/29335031/respiration-pattern-variability-and-related-default-mode-network-connectivity-are-altered-in-remitted-depression
#4
Vera Eva Zamoscik, Stephanie Nicole Lyn Schmidt, Martin Fungisai Gerchen, Christos Samsouris, Christina Timm, Christine Kuehner, Peter Kirsch
BACKGROUND: Studies with healthy participants and patients with respiratory diseases suggest a relation between respiration and mood. The aim of the present analyses was to investigate whether emotionally challenged remitted depressed participants show higher respiration pattern variability (RPV) and whether this is related to mood, clinical outcome and increased default mode network connectivity. METHODS: To challenge participants, sad mood was induced with keywords of personal negative life events in individuals with remitted depression [recurrent major depressive disorder (rMDD), n = 30] and matched healthy controls (HCs, n = 30) during functional magnetic resonance imaging...
January 16, 2018: Psychological Medicine
https://www.readbyqxmd.com/read/29332091/the-association-among-default-mode-network-functional-connectivity-mentalization-and-psychopathology-in-a-nonclinical-sample-an-eloreta-study
#5
Benedetto Farina, Giacomo Della Marca, Giulia Maestoso, Noemi Amoroso, Enrico Maria Valenti, Giuseppe Alessio Carbone, Chiara Massullo, Anna Contardi, Claudio Imperatori
AIMS: We investigated default mode network (DMN) electroencephalography (EEG) functional connectivity differences between individuals with self-reported high mentalization capability and low psychopathological symptoms, versus participants with mentalization impairments and high psychopathological symptoms. METHODS: Forty-nine students (35 women) with a mean age of 22.92 ± 2.53 years were administered the Mentalization Questionnaire (MZQ) and the Symptom Checklist-90-Revised...
January 13, 2018: Psychopathology
https://www.readbyqxmd.com/read/29330134/a-supplementary-functional-connectivity-microstate-attached-to-the-default-mode-network-in-depression-revealed-by-resting-state-magnetoencephalography
#6
Siqi Zhang, Shui Tian, Mohammad Ridwan Chattun, Hao Tang, Rui Yan, Kun Bi, Zhijian Yao, Qing Lu
Default mode network (DMN) has discernable involvement in the representation of negative, self-referential information in depression. Both increased and decreased resting-state functional connectivity between the anterior and posterior DMN have been observed in depression. These conflicting connectivity differences necessitated further exploration of the resting-state DMN dysfunction in depression. Hence, we investigated the time-varying dynamic interactions within the DMN via functional connectivity microstates in a sub-second level...
January 9, 2018: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/29323797/relations-between-cortical-thickness-serotonin-1a-receptor-binding-and-structural-connectivity-a-multimodal-imaging-study
#7
Rajapillai L I Pillai, Ashwin Malhotra, Deborah D Rupert, Bennett Weschler, John C Williams, Mengru Zhang, Jie Yang, J John Mann, Maria A Oquendo, Ramin V Parsey, Christine DeLorenzo
Serotonin 1A (5-HT1A ) receptors play a direct role in neuronal development, cell proliferation, and dendritic branching. We hypothesized that variability in 5-HT1A binding can affect cortical thickness, and may account for a subtype of major depressive disorder (MDD) in which both are altered. To evaluate this, we measured cortical thickness from structural magnetic resonance imaging (MRI) and 5-HT1A binding by positron emission tomography (PET) in an exploratory study. To examine a range of 5-HT1A binding and cortical thickness values, we recruited 25 healthy controls and 19 patients with MDD...
February 2018: Human Brain Mapping
https://www.readbyqxmd.com/read/29322586/functional-connectivity-predicts-gender-evidence-for-gender-differences-in-resting-brain-connectivity
#8
Chao Zhang, Chase C Dougherty, Stefi A Baum, Tonya White, Andrew M Michael
Prevalence of certain forms of psychopathology, such as autism and depression, differs between genders and understanding gender differences of the neurotypical brain may provide insights into risk and protective factors. In recent research, resting state functional magnetic resonance imaging (rfMRI) is widely used to map the inherent functional networks of the brain. Although previous studies have reported gender differences in rfMRI, the robustness of gender differences is not well characterized. In this study, we use a large data set to test whether rfMRI functional connectivity (FC) can be used to predict gender and identify FC features that are most predictive of gender...
January 10, 2018: Human Brain Mapping
https://www.readbyqxmd.com/read/29315984/default-mode-network-modifications-in-fabry-disease-a-resting-state-fmri-study-with-structural-correlations
#9
Sirio Cocozza, Giuseppe Pontillo, Mario Quarantelli, Francesco Saccà, Eleonora Riccio, Teresa Costabile, Gaia Olivo, Vincenzo Brescia Morra, Antonio Pisani, Arturo Brunetti, Enrico Tedeschi
Aim of the study was to evaluate the presence of Default Mode Network (DMN) modifications in Fabry Disease (FD), and their possible correlations with structural alterations and neuropsychological scores. Thirty-two FD patients with a genetically confirmed diagnosis of classical FD (12 males, mean age 43.3 ± 12.2) were enrolled, along with 35 healthy controls (HC) of comparable age and sex (14 males, mean age 42.1 ± 14.5). Resting-State fMRI data were analyzed using a seed-based approach, with six different seeds sampling the main hubs of the DMN...
January 9, 2018: Human Brain Mapping
https://www.readbyqxmd.com/read/29315459/pretherapeutic-functional-neuroimaging-predicts-tremor-arrest-after-thalamotomy
#10
C Tuleasca, E Najdenovska, J Régis, T Witjas, N Girard, J Champoudry, M Faouzi, J-P Thiran, M Bach Cuadra, M Levivier, D Van De Ville
OBJECTIVE: Essential tremor (ET) represents the most common movement disorder. Drug-resistant ET can benefit from standard stereotactic procedures (deep brain stimulation or radiofrequency thalamotomy) or alternatively minimally invasive high-focused ultrasound or radiosurgery. All aim at same target, thalamic ventro-intermediate nucleus (Vim). METHODS: The study included a cohort of 17 consecutive patients, with ET, treated only with left unilateral stereotactic radiosurgical thalamotomy (SRS-T) between September 2014 and August 2015...
January 7, 2018: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/29315361/networks-of-tau-distribution-in-alzheimer-s-disease
#11
Merle C Hoenig, Gérard N Bischof, Joseph Seemiller, Jochen Hammes, Juraj Kukolja, Özgür A Onur, Frank Jessen, Klaus Fliessbach, Bernd Neumaier, Gereon R Fink, Thilo van Eimeren, Alexander Drzezga
A stereotypical anatomical propagation of tau pathology has been described in Alzheimer's disease. According to recent concepts (network degeneration hypothesis), this propagation is thought to be indicative of misfolded tau proteins possibly spreading along functional networks. If true, tau pathology accumulation should correlate in functionally connected brain regions. Therefore, we examined whether independent components could be identified in the distribution pattern of in vivo tau pathology and whether these components correspond with specific functional connectivity networks...
January 5, 2018: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/29314426/the-role-of-the-dorsal-anterior-insula-in-sexual-risk-evidence-from-an-erotic-go-nogo-task-and-real-world-risk-taking
#12
Feng Xue, Vita Droutman, Emily E Barkley-Levenson, Benjamin J Smith, Gui Xue, Lynn C Miller, Antoine Bechara, Zhong-Lin Lu, Stephen J Read
The insula plays an important role in response inhibition. Most relevant here, it has been proposed that the dorsal anterior insular cortex (dAIC) plays a central role in a salience network that is responsible for switching between the default mode network and the executive control network. However, the insula's role in sexually motivated response inhibition has not yet been studied. In this study, eighty-five 18- to 30-year-old sexually active men who have sex with men (MSM) performed an erotic Go/NoGo task while in an MRI scanner...
January 3, 2018: Human Brain Mapping
https://www.readbyqxmd.com/read/29314415/differentially-categorized-structural-brain-hubs-are-involved-in-different-microstructural-functional-and-cognitive-characteristics-and-contribute-to-individual-identification
#13
Xindi Wang, Qixiang Lin, Mingrui Xia, Yong He
Very little is known regarding whether structural hubs of human brain networks that enable efficient information communication may be classified into different categories. Using three multimodal neuroimaging data sets, we construct individual structural brain networks and further identify hub regions based on eight widely used graph-nodal metrics, followed by comprehensive characteristics and reproducibility analyses. We show the three categories of structural hubs in the brain network, namely, aggregated, distributed, and connector hubs...
January 4, 2018: Human Brain Mapping
https://www.readbyqxmd.com/read/29310911/attenuated-resting-state-functional-connectivity-in-patients-with-childhood-and-adult-onset-schizophrenia
#14
Rebecca E Watsky, Stephen J Gotts, Rebecca A Berman, Harrison M McAdams, Xueping Zhou, Dede Greenstein, Francois M Lalonde, Peter Gochman, Liv S Clasen, Lorie Shora, Anna E Ordóñez, Nitin Gogtay, Alex Martin, Deanna M Barch, Judith L Rapoport, Siyuan Liu
BACKGROUND: Childhood-onset schizophrenia (COS) is a rare, severe form of the adult-onset disorder (AOS). Our previous resting-state fMRI study identified attenuated functional connectivity in COS compared with controls. Here, we ask whether COS and AOS patients and their siblings exhibit similar abnormalities of functional connectivity. METHODS: A whole-brain, data-driven approach was used to assess resting-state functional connectivity differences in COS (patients/siblings/controls, n: 26/28/33) and AOS (n: 19/28/30)...
January 6, 2018: Schizophrenia Research
https://www.readbyqxmd.com/read/29309541/fibre-specific-white-matter-reductions-in-alzheimer-s-disease-and-mild-cognitive-impairment
#15
Remika Mito, David Raffelt, Thijs Dhollander, David N Vaughan, J-Donald Tournier, Olivier Salvado, Amy Brodtmann, Christopher C Rowe, Victor L Villemagne, Alan Connelly
Alzheimer's disease is increasingly considered a large-scale network disconnection syndrome, associated with progressive aggregation of pathological proteins, cortical atrophy, and functional disconnections between brain regions. These pathological changes are posited to arise in a stereotypical spatiotemporal manner, targeting intrinsic networks in the brain, most notably the default mode network. While this network-specific disruption has been thoroughly studied with functional neuroimaging, changes to specific white matter fibre pathways within the brain's structural networks have not been closely investigated, largely due to the challenges of modelling complex white matter structure...
January 4, 2018: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/29306697/current-sleep-disturbance-in-older-people-with-a-lifetime-history-of-depression-is-associated-with-increased-connectivity-in-the-default-mode-network
#16
Andrew C McKinnon, Ian B Hickie, Jan Scott, Shantel L Duffy, Louisa Norrie, Zoe Terpening, Ron R Grunstein, Jim Lagopoulos, Jennifer Batchelor, Simon J G Lewis, James M Shine, Sharon L Naismith
BACKGROUND: The present study investigated Default Mode Network (DMN) functional connectivity in subjects with a lifetime history of major depression, comparing those with and without current sleep disturbance. Controls were included to assess DMN abnormalities specific to depression. METHODS: A total of 93 adults aged 50 years and over were recruited from the Healthy Brain Ageing Clinic at the Brain and Mind Centre, Sydney, Australia. The sample comprised two groups, including 22 controls and 71 participants with a lifetime history of DSM-IV major depression (with depressive episode current or remitted)...
December 29, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29300840/reconfiguration-of-cortical-networks-in-mdd-uncovered-by-multiscale-community-detection-with-fmri
#17
Ye He, Sol Lim, Santo Fortunato, Olaf Sporns, Lei Zhang, Jiang Qiu, Peng Xie, Xi-Nian Zuo
Major depressive disorder (MDD) is known to be associated with altered interactions between distributed brain regions. How these regional changes relate to the reorganization of cortical functional systems, and their modulation by antidepressant medication, is relatively unexplored. To identify changes in the community structure of cortical functional networks in MDD, we performed a multiscale community detection algorithm on resting-state functional connectivity networks of unmedicated MDD (uMDD) patients (n = 46), medicated MDD (mMDD) patients (n = 38), and healthy controls (n = 50), which yielded a spectrum of multiscale community partitions...
December 28, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/29299691/knowing-left-from-right-asymmetric-functional-connectivity-during-resting-state
#18
Mathijs Raemaekers, Wouter Schellekens, Natalia Petridou, Nick F Ramsey
The functional organization of left and right hemispheres is different, and hemispheric asymmetries are thought to underlie variations in brain function across individuals. In this study, we assess how differences between hemispheres are reflected in Asymmetric Functional Connectivity (AFC), which provides a full description of how the brain's connectivity structure during resting state differs from that of the same brain mirrored over the longitudinal fissure. In addition, we assess how AFC varies across subjects...
January 4, 2018: Brain Structure & Function
https://www.readbyqxmd.com/read/29299380/higher-extrinsic-and-lower-intrinsic-connectivity-in-resting-state-networks-for-professional-baduk-go-players
#19
William S Sohn, Tae Young Lee, Seoyeon Kwak, Youngwoo Bryan Yoon, Jun Soo Kwon
Introduction: Dedication and training to a profession results in a certain level of expertise. This expertise, like any other skill obtained in our lifetime, is encoded in the brain and may be reflected in our brain's connectome. This property can be observed by mapping resting state connectivity. In this study, we examine the differences in resting state functional connectivity in four major networks between professional "Baduk" (Go) players and normal subjects. Methods: Resting state fMRI scans were acquired for professional "Baduk" (Go) players and normal controls...
December 2017: Brain and Behavior
https://www.readbyqxmd.com/read/29299378/moral-processing-deficit-in-behavioral-variant-frontotemporal-dementia-is-associated-with-facial-emotion-recognition-and-brain-changes-in-default-mode-and-salience-network-areas
#20
Jan Van den Stock, Daphne Stam, François-Laurent De Winter, Dante Mantini, Benedikt Szmrecsanyi, Koen Van Laere, Rik Vandenberghe, Mathieu Vandenbulcke
Introduction: Behavioral variant frontotemporal dementia (bvFTD) is associated with abnormal emotion recognition and moral processing. Methods: We assessed emotion detection, discrimination, matching, selection, and categorization as well as judgments of nonmoral, moral impersonal, moral personal low- and high-conflict scenarios. Results: bvFTD patients gave more utilitarian responses on low-conflict personal moral dilemmas. There was a significant correlation between a facial emotion processing measure derived through principal component analysis and utilitarian responses on low-conflict personal scenarios in the bvFTD group (controlling for MMSE-score and syntactic abilities)...
December 2017: Brain and Behavior
keyword
keyword
33748
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"