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Natalie N Merchant, Robert McKenna, Osita Onugha
Lung cancer is the second most commonly diagnosed cancer and continues to be the leading cause of death for both men and women, with non-small cell lung cancer (NSCLC) accounting for 85% of all lung cancer cases. Once a lung mass is visualized on imaging, accurate staging is required for determination of treatment options and, when possible, surgical resection is recommended as it has been proven to have the best survival rates versus non-surgical treatment. If a patient has advanced or metastatic disease, therapeutic options include chemotherapy and radiation, while immunotherapy and specific agents that target tumor mutations are only recommended for appropriate candidates...
June 1, 2018: Surgical Technology International
Sunil V Patel, Patti A Groome, Shaila Merchant, Katherine Lajkosz, Sulaiman Nanji, Susan B Brogly
BACKGROUND: Delays in surgery for patients with acute appendicitis may increase the risk of perforation and complications. These risks must be balanced with the theoretical risk of night time operations. OBJECTIVE: To determine the effect of (i) time of day of surgery and (ii) time between triage presentation and surgery, on surgical complications in patient undergoing appendectomy for appendicitis. METHODS: Population level data from Ontario from 2009 - 2015 was used to conduct this retrospective cohort study...
May 4, 2018: Journal of Trauma and Acute Care Surgery
Benjamin L Ranard, Raina M Merchant
No abstract text is available yet for this article.
May 22, 2018: Circulation
Kajsa Ugelvig Petersen, Julie Volk, Linda Kaerlev, Henrik Lyngbeck Hansen, Johnni Hansen
OBJECTIVES: While maritime safety generally has improved dramatically over the last century, modern seafarers are still faced with numerous occupational hazards potentially affecting their risk of chronic diseases such as cancer. The aim of this study is to offer updated information on the incidence of specific cancers among both male and female seafarers. METHODS: Using records from the Danish Seafarer Registry, all seafarers employed on Danish ships during 1986-1999 were identified, resulting in a cohort of 33 084 men and 11 209 women...
May 19, 2018: Occupational and Environmental Medicine
Giles W Robinson, Vasilisa A Rudneva, Ivo Buchhalter, Catherine A Billups, Sebastian M Waszak, Kyle S Smith, Daniel C Bowers, Anne Bendel, Paul G Fisher, Sonia Partap, John R Crawford, Tim Hassall, Daniel J Indelicato, Frederick Boop, Paul Klimo, Noah D Sabin, Zoltan Patay, Thomas E Merchant, Clinton F Stewart, Brent A Orr, Jan O Korbel, David T W Jones, Tanvi Sharma, Peter Lichter, Marcel Kool, Andrey Korshunov, Stefan M Pfister, Richard J Gilbertson, Robert P Sanders, Arzu Onar-Thomas, David W Ellison, Amar Gajjar, Paul A Northcott
BACKGROUND: Young children with medulloblastoma have a poor overall survival compared with older children, due to use of radiation-sparing therapy in young children. Radiotherapy is omitted or reduced in these young patients to spare them from debilitating long-term side-effects. We aimed to estimate event-free survival and define the molecular characteristics associated with progression-free survival in young patients with medulloblastoma using a risk-stratified treatment strategy designed to defer, reduce, or delay radiation exposure...
May 16, 2018: Lancet Oncology
B Bhoyrul, E Carling, W Merchant, G I Stables
No abstract text is available yet for this article.
May 19, 2018: Clinical and Experimental Dermatology
Temesgen Fiseha, Ermiyas Alemayehu, Wongelawit Kassahun, Aderaw Adamu, Angesom Gebreweld
OBJECTIVE: The aim of this study was to determine the status of glycemic control and identify factors associated with poor glycemic control among diabetic out-patients. RESULTS: A hospital based cross-sectional study was conducted among randomly selected 384 (126 type 1 and 258 type 2) diabetic adults attending a hospital in Northeast Ethiopia from January 1 to April 30, 2017. Of the total participants, 70.8% had poor status of glycemic control (defined as mean fasting blood glucose level above 130 mg/dl)...
May 18, 2018: BMC Research Notes
Christine B Sethna, Kumail Merchant, Abigail Reyes
Cardiovascular disease is a major cause of death in individuals diagnosed with kidney disease during childhood. Children with kidney disease often incur a significant cardiovascular burden that leads to increased risk for cardiovascular disease. Evidence has shown that children with kidney disease, including chronic kidney disease, dialysis, kidney transplantation, and nephrotic syndrome, develop abnormalities in cardiovascular markers such as hypertension, dyslipidemia, left ventricular hypertrophy, left ventricular dysfunction, atherosclerosis, and aortic stiffness...
May 2018: Seminars in Nephrology
Adrian W Gelb, Wayne W Morriss, Walter Johnson, Alan F Merry, Anuja Abayadeera, Natalia Belîi, Sorin J Brull, Aline Chibana, Faye Evans, Cyril Goddia, Carolina Haylock-Loor, Fauzia Khan, Sandra Leal, Nan Lin, Richard Merchant, Mark W Newton, Jackie S Rowles, Arinola Sanusi, Iain Wilson, Adriana Velazquez Berumen
The International Standards for a Safe Practice of Anesthesia were developed on behalf of the World Federation of Societies of Anaesthesiologists (WFSA), a nonprofit organization representing anesthesiologists in 150 countries, and the World Health Organization (WHO). The recommendations have been approved by WHO and the membership of WFSA. These Standards are applicable to all anesthesia providers throughout the world. They are intended to provide guidance and assistance to anesthesia providers, their professional organizations, hospital and facility administrators, and governments for maintaining and improving the quality and safety of anesthesia care...
June 2018: Anesthesia and Analgesia
Gregory C Smith, Bert Hayslip, Gregory R Hancock, William Merchant, Julian Montoro-Rodriguez, Frederick Strieder
There is scant research on how the parenting practices of custodial grandmothers affect the psychological adjustment of grandchildren in their care. Yet, the findings from a handful of prior studies suggest the relevance of the Family Stress Model (FSM) to these caregivers. The present study further tested the FSM with baseline data from 343 custodial grandmothers (Mage = 58.5 years) enrolled in a clinical trial of the efficacy of interventions for improving the well-being of their families. Not only was this "help-seeking" sample atypical of prior FSM studies, but also unique to the present study was our addition of multiple parenting practices, self-reported and clinical ratings of grandmothers' distress, and reports of grandchildren's internalizing and externalizing difficulties from grandchildren and grandmothers...
February 2018: Journal of Child and Family Studies
Vaishali Korranne, Yash Merchant, Samir Joshi, Rajshekhar Halli
The dentinogenic ghost cell tumor (DGCT) is a relatively uncommon locally invasive neoplasm that mimics several inflammatory/reactive lesions of the gingiva or odontogenic cysts. The confirmatory diagnosis of this rare lesion can only be made with histopathological examination. Routine staining reveals features of a "mixed" tumor as ghost cells with calcification, dysplastic dentin and islands of epithelium in rosette pattern in mature connective tissue are visible. The case report describes an asymptomatic growth in the maxillary gingiva of a young patient that was incidentally diagnosed as a DGCT after biopsy...
January 2018: Journal of Oral and Maxillofacial Pathology: JOMFP
Mathew R Levy, Faisal M Merchant, Jonathan J Langberg, David B Delurgio
Background: The utility of standard distal bipolar electrograms (sEGMs) for assessing catheter-tissue contact may be obscured by the presence of far-field signals. Microelectrode electrograms (mEGMs) may overcome this limitation. Methods: We compared 5 mEGM characteristics (amplitude, frequency content, temporal signal variability, presence of injury current, and amplitude differential between bipoles) with the sEGM for determining tissue contact in 20 patients undergoing ablation of typical atrial flutter...
February 2018: Journal of Arrhythmia
Michael L Merchant, Michael E Brier, Mark S Slaughter, Jon B Klein, Kenneth R McLeish
BACKGROUND: Acute kidney injury (AKI) is a common post-cardiac surgery complication and influences patient morbidity and prognosis. This study was designed to identify preoperative candidate urine biomarkers in patients undergoing cardiac surgery. METHODS: A prospective cohort study of adults undergoing cardiac surgery at increased risk for AKI at a single hospital between July 2010 and September 2012 was performed. The primary outcome was the development of AKI, defined as an absolute serum creatinine (SCr) level increase ≥ 0...
May 2, 2018: BMC Nephrology
Alessandro Satriano, Zachary Guenther, James A White, Naeem Merchant, Elena S Di Martino, Faisal Al-Qoofi, Carmen P Lydell, Nowell M Fine
BACKGROUND: Functional impairment of the aorta is a recognized complication of aortic and aortic valve disease. Aortic strain measurement provides effective quantification of mechanical aortic function, and 3-dimenional (3D) approaches may be desirable for serial evaluation. Computerized tomographic angiography (CTA) is routinely performed for various clinical indications, and offers the unique potential to study 3D aortic deformation. We sought to investigate the feasibility of performing 3D aortic strain analysis in a candidate population of patients undergoing transcatheter aortic valve replacement (TAVR)...
May 2, 2018: BMC Cardiovascular Disorders
B Fougère, M Cesari, H Arai, J Woo, R A Merchant, L Flicker, A Cherubini, J M Bauer, B Vellas, J E Morley
No abstract text is available yet for this article.
2018: Journal of Nutrition, Health & Aging
Juanita L Merchant
No abstract text is available yet for this article.
2018: Cellular and Molecular Gastroenterology and Hepatology
Myron P Gutmann, Emily Klancher Merchant, Evan Roberts
Big data is an exciting prospect for the field of economic history, which has long depended on the acquisition, keying, and cleaning of scarce numerical information about the past. This article examines two areas in which economic historians are already using big data - population and environment - discussing ways in which increased frequency of observation, denser samples, and smaller geographic units allow us to analyze the past with greater precision and often to track individuals, places, and phenomena across time...
March 2018: Journal of Economic History
Timothy A C Gordon, Harry R Harding, Kathryn E Wong, Nathan D Merchant, Mark G Meekan, Mark I McCormick, Andrew N Radford, Stephen D Simpson
Coral reefs are increasingly degraded by climate-induced bleaching and storm damage. Reef recovery relies on recruitment of young fishes for the replenishment of functionally important taxa. Acoustic cues guide the orientation, habitat selection, and settlement of many fishes, but these processes may be impaired if degradation alters reef soundscapes. Here, we report spatiotemporally matched evidence of soundscapes altered by degradation from recordings taken before and after recent severe damage on Australia's Great Barrier Reef...
April 30, 2018: Proceedings of the National Academy of Sciences of the United States of America
Chao Li, Ralph B D'Agostino, Dana Dabelea, Angela D Liese, Elizabeth J Mayer-Davis, Russell Pate, Anwar T Merchant
BACKGROUND: Few studies have evaluated the prospective association of eating frequency with HbA1c levels and cardiovascular disease risk markers among youth with diabetes. OBJECTIVE: To examine the 5-year longitudinal association of eating frequency with HbA1c and serum lipid levels among youth with type 1 diabetes (T1D) or type 2 diabetes (T2D). METHODS: 1,049 youth (≥10 years old) with incident T1D (n=821) or T2D (n=228) who participated in the SEARCH for Diabetes in Youth Study were included...
April 30, 2018: Pediatric Diabetes
Jorge Gámez, Karyna Yc, Yaneri A Ayala, Dobromir Dotov, Luis Prado, Hugo Merchant
Beat entrainment is the ability to entrain one's movements to a perceived periodic stimulus, such as a metronome or a pulse in music. Humans have a capacity to predictively respond to a periodic pulse and to dynamically adjust their movement timing to match the varying music tempos. Previous studies have shown that monkeys share some of the human capabilities for rhythmic entrainment, such as tapping regularly at the period of isochronous stimuli. However, it is still unknown whether monkeys can predictively entrain to dynamic tempo changes like humans...
April 30, 2018: Annals of the New York Academy of Sciences
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