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https://www.readbyqxmd.com/read/29336034/quantitative-evaluation-of-collagen-and-elastic-fibers-after-intense-pulsed-light-treatment-of-mouse-skin
#1
Luciana L Faucz, Sonia E Will, Consuelo J Rodrigues, Henrique Hesse, Angelina C Moraes, Durvanei A Maria
BACKGROUND AND OBJECTIVE: The aging of human skin includes intrinsic aging and photo-aging, which are characterized by a decrease in collagen and the deposition of abnormal elastic fibers. Intense pulsed light (IPL) sources are widely used in medicine to treat various cosmetic problems, including photo-damaged skin. Few studies have examined the microscopic changes produced by IPL. The objective of this study was to quantitatively evaluate the effects of IPL on collagen and elastic fibers in mice...
January 16, 2018: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/29333752/workplace-design-for-the-australian-residential-aged-care-workforce
#2
Lucio Naccarella, Clare Newton, Alan Pert, Kurt Seemann, Ruth Williams, Kate Sellick, Briony Dow
OBJECTIVES: This research explored residential aged care (RAC) workplace design features that influence how RAC staff feel valued, productive, safe, like they belong and connected. A secondary aim was to validate emerging themes about RAC design features with stakeholders. METHODS: A multistage qualitative study was conducted in one RAC facility with 100 residents in outer metropolitan Melbourne: (i) photo-elicitation - photographs were used to prompt discussions with RAC staff; (ii) individual interviews with RAC directors; and (iii) validity testing with the advisory committee occurred...
January 14, 2018: Australasian Journal on Ageing
https://www.readbyqxmd.com/read/29316789/super-resolution-monitoring-of-mitochondrial-dynamics-upon-time-gated-photo-triggered-release-of-nitric-oxide
#3
Haihong He, Zhiwei Ye, Yi Xiao, Wei Yang, Xuhong Qian, Youjun Yang
Nitric oxide (NO) potentially plays a regulatory role in mitochondrial fusion and fission, which are vital to cell survival and implicated in health, disease and ageing. Molecular tools facilitating study of the interrelationship between NO and mito-chondrial dynamics are in need. We have recently developed a novel NO donor (NOD550). Upon photo-activation, NOD550 decomposes to release two NO molecules and a fluorophore. The NO release could be spatially mapped with sub-diffraction resolution and with a temporal resolution of 10 s...
January 10, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/29312653/while-reinforcing-cell-cycle-arrest-rapamycin-and-torins-suppress-senescence-in-uva-irradiated-fibroblasts
#4
Olga V Leontieva, Mikhail V Blagosklonny
Sunlight predisposes to skin cancer and melanomas. Ultraviolet A (UVA), a long wave component of sunlight, can reach dermal fibroblasts. Here we studied UVA-induced senescence in human fibroblasts in vitro. It is known that senescence occurs, when cell cycle is arrested, but mTOR is still active, thus converting arrest to senescence (geroconversion). We showed that, while arresting cell cycle, UVA did not inhibit mTOR, enabling geroconversion. In UVA-treated cells, mTOR remained fully active. Rapamycin and Torins 1/ 2 prevented UVA-induced senescent phenotype, although they further re-enforced cell cycle arrest...
December 12, 2017: Oncotarget
https://www.readbyqxmd.com/read/29290273/effectiveness-of-cognitive-behavioral-program-on-pain-and-fear-in-school-aged-children-undergoing-intravenous-placement
#5
Yi-Chuan Hsieh, Su-Fen Cheng, Pei-Kwei Tsay, Wen-Jen Su, Yen-Hua Cho, Chi-Wen Chen
PURPOSE: This study aimed to evaluate the effects of cognitive-behavioral program on pain and medical fear in hospitalized school-aged children receiving intravenous (IV) placement. METHODS: This study used an quasi-experimental design. Thirty-five participants were assigned to the experimental group and 33 to the control group in the acute internal medicine ward of a children's hospital. The cognitive-behavioral program entailed having the patients read an educational photo book about IV placement before the procedure and having them watch their favorite music video during the procedure...
December 2017: Asian Nursing Research
https://www.readbyqxmd.com/read/29289789/zoledronic-acid-increases-the-prevalence-of-medication-related-osteonecrosis-of-the-jaw-in-a-dose-dependent-manner-in-rice-rats-oryzomys-palustris-with-localized-periodontitis
#6
J G Messer, J L Mendieta Calle, J M Jiron, E J Castillo, C Van Poznak, N Bhattacharyya, D B Kimmel, J I Aguirre
OBJECTIVE: Investigate role of dose/duration of zoledronic acid (ZOL), a powerful anti-resorptive (pAR), on prevalence of medication-related osteonecrosis of the jaw (MRONJ) in rice rats (Oryzomys palustris), a species with natural susceptibility to food impaction-induced localized periodontitis (FILP). We hypothesize that ZOL induces MRONJ lesions in rice rats with FILP, and that the prevalence of MRONJ rises with increasing dose and duration of ZOL treatment. METHODS: We performed a toxicology experiment with clinically-relevant doses of ZOL in female rats (N=230) fed standard (STD) rodent chow...
December 28, 2017: Bone
https://www.readbyqxmd.com/read/29286636/topology-of-intermetallic-structures-from-statistics-to-rational-design
#7
Tatiana G Akhmetshina, Vladislav A Blatov, Davide M Proserpio, Alexander P Shevchenko
More than 38 000 substances made only of metal atoms are collected in modern structural databases; we may call them intermetallic compounds. They have important industrial applications, and yet they are terra incognita for most of our undergraduate students. Their structural complexity and synthesis are not easily adaptable to first years laboratories, keeping them away from the standard curricula. They have been described over the years following alternative and complementary views such as coordination polyhedra, atomic layers, and polyatomic clusters...
December 29, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/29284353/-going-to-the-gym-is-not-congolese-s-culture-examining-attitudes-toward-physical-activity-and-risk-for-type-2-diabetes-among-congolese-immigrants
#8
Daudet Ilunga Tshiswaka, Kelechi D Ibe-Lamberts, Guy-Lucien S Whembolua, Abi Fapohunda, Eugene S Tull
Purpose The purpose of this study was to explore perceptions and attitudes around physical activity among immigrants from the Democratic Republic of Congo and examine the influence of Congolese cultural beliefs on physical activity practice. Methods In-depth interviews were conducted and augmented by photo-elicitation among 20 Congolese immigrants, distributed equally by gender, aged 35 years or older. The PEN-3 model was used as the cultural conceptual framework. Results Using both the Relationships and Expectations dimension (Perceptions, Enablers, and Nurturers) and Cultural Empowerment dimension (Positive, Existential, and Negative) of the PEN-3 model, emergent themes were categorized around knowing the benefits of being physically active (perceptions), doctor encouragement to be more physically active (enablers), and the habit and local tradition of consuming beer after a soccer match (nurturers)...
December 1, 2017: Diabetes Educator
https://www.readbyqxmd.com/read/29279683/evaluation-of-child-preference-for-dentist-attire-and-usage-of-camouflage-syringe-in-reduction-of-anxiety
#9
Prashant Babaji, Pavni P Chauhan, Vikram Rathod, Swapnil Mhatre, Uttam Paul, Guneet Guram
Objectives: The aim of this study is to evaluate the child preference for dentist attire and camouflage versus conventional syringe in reduction of anxiety. Materials and Methods: A total of 600 children aged 6-14 years were made to look at a set of six photos of an individual dressed with different colored apron of pink, green, blue, white colors, formal dress, and cartoon character along with conventional syringe and camouflage syringe with a toy-like appearance to permit injection of local anesthesia...
October 2017: European Journal of Dentistry
https://www.readbyqxmd.com/read/29235107/headache-characteristics-and-clinical-features-of-elderly-migraine-patients
#10
Pablo de Rijk, Noémie Resseguier, Anne Donnet
OBJECTIVE: To investigate the headache characteristics and clinical features of elderly migraine patients at a tertiary headache center. METHODS: We retrospectively reviewed 239 records of migraine patients, over the age of 64 at the first visit, who had migraine as defined by the International Classification of Headache Disorders 3rd edition (beta version) from 2006 to 2015 based on the Marseille registry at Timone Hospital. RESULTS: 13.8% (33/239) patients had migraine with aura only, 13...
December 13, 2017: Headache
https://www.readbyqxmd.com/read/29230841/photoaggravated-allergic-contact-dermatitis-and-transient-photosensitivity-caused-by-methylisothiazolinone
#11
Olivier Aerts, An Goossens, Marie-Claude Marguery, Michel Castelain, Lucile Boursault, Françoise Giordano-Labadie, Julien Lambert, Brigitte Milpied
BACKGROUND: Photoaggravated allergic contact dermatitis caused by methylchloroisothiazolinone (MCI)/methylisothiazolinone (MI) and MI has been reported. OBJECTIVES: To describe the clinical characteristics and results of (photo)patch tests and photo-tests of 10 patients in Belgium and France suffering from photoaggravated contact dermatitis caused by MI. PATIENTS AND METHODS: Five men and five women, with a median age of 49.5 years, were investigated between January 2012 and February 2017 because of suspected photoaggravated contact dermatitis...
December 12, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/29227822/automated-retinal-health-diagnosis-using-pyramid-histogram-of-visual-words-and-fisher-vector-techniques
#12
Joel E W Koh, Eddie Y K Ng, Sulatha V Bhandary, Yuki Hagiwara, Augustinus Laude, U Rajendra Acharya
Untreated age-related macular degeneration (AMD), diabetic retinopathy (DR), and glaucoma may lead to irreversible vision loss. Hence, it is essential to have regular eye screening to detect these eye diseases at an early stage and to offer treatment where appropriate. One of the simplest, non-invasive and cost-effective techniques to screen the eyes is by using fundus photo imaging. But, the manual evaluation of fundus images is tedious and challenging. Further, the diagnosis made by ophthalmologists may be subjective...
December 5, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/29226058/towards-fingermark-dating-a-raman-spectroscopy-proof-of-concept-study
#13
Per Ola Andersson, Christian Lejon, Therese Mikaelsson, Lars Landström
Fingermarks have, for a long time, been vital in the forensic community for the identification of individuals, and a possibility to non-destructively date the fingermarks would of course be beneficial. Raman spectroscopy is, herein, evaluated for the purpose of estimating the age of fingermarks deposits. Well-resolved spectra were non-destructively acquired to reveal spectral uniqueness, resembling those of epidermis, and several molecular markers were identified that showed different decay kinetics: carotenoids > squalene > unsaturated fatty acids > proteins...
December 2017: ChemistryOpen
https://www.readbyqxmd.com/read/29224907/quantitative-postural-analysis-of-children-with-congenital-visual-impairment
#14
Michelle de Pádua, Juliana F Sauer, Silvia M A João
OBJECTIVES: The aim of this study was to compare the postural alignment of children with visual impairment with that of children without visual impairment. METHODS: The sample studied was 74 children of both sexes ages 5 to 12 years. Of these, 34 had visual impairment and 40 were control children. Digital photos from the standing position were used to analyze posture. Postural variables, such as tilt of the head, shoulder position, scapula position, lateral deviation of the spine, ankle position in the frontal plane and head posture, angle of thoracic kyphosis, angle of lumbar lordosis, pelvis position, and knee position in the frontal and sagittal planes, were measured with the Postural Assessment Software 0...
December 7, 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/29210971/understanding-age-memories-and-how-they-impact-aesthetic-practice
#15
Lovely C Laban
According to the American Society for Aesthetic Plastic Surgery (), the number of nonsurgical treatments grew 650% from 1996 to 2016. As these procedures have evolved and improved, so have their ability to deliver results that enhance one's natural beauty and reverse the signs of aging. Many patients seek these procedures in the hopes of looking younger and more refreshed, but "younger" can be subjective and the patient's desired outcome may be difficult for practitioners to interpret. A recent study () of 350 women found that patients are carrying around a "memory photo" of themselves that is about 10 years younger than their actual age...
October 2017: Plastic Surgical Nursing
https://www.readbyqxmd.com/read/29207534/effects-of-the-macular-carotenoid-lutein-in-human-retinal-pigment-epithelial-cells
#16
Xiaoming Gong, Christian S Draper, Geoffrey S Allison, Raju Marisiddaiah, Lewis P Rubin
Retinal pigment epithelial (RPE) cells are central to retinal health and homoeostasis. Oxidative stress-induced damage to the RPE occurs as part of the pathogenesis of age-related macular degeneration and neovascular retinopathies (e.g., retinopathy of prematurity, diabetic retinopathy). The xanthophyll carotenoids, lutein and zeaxanthin, are selectively taken up by the RPE, preferentially accumulated in the human macula, and transferred to photoreceptors. These macular xanthophylls protect the macula (and the broader retina) via their antioxidant and photo-protective activities...
December 4, 2017: Antioxidants (Basel, Switzerland)
https://www.readbyqxmd.com/read/29201036/nitrogen-deposition-enhances-photosynthesis-in-moso-bamboo-but-increases-susceptibility-to-other-stress-factors
#17
Rui Zhang, Jiasheng Wu, Quan Li, Heikki Hänninen, Chunju Peng, Hang Yao, Xinzhang Song, Yeqing Ying
Atmospheric nitrogen (N) deposition can increase the susceptibility of vascular plants to other stresses, but the physiological basis of such a response remains poorly understood. This study was designed to clarify the physiological mechanisms and to evaluate bioindicators of N deposition impact on vascular plants. We evaluate multiple physiological responses to ~4 years of simulated additional N deposition (30-90 kg N ha-1 year-1) on three age-classes (1a, 3a, and 5a) of Moso bamboo. A saturating response to the additional N deposition was found both in foliar N concentration and in Pn...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29196768/macular-atrophy-development-and-subretinal-drusenoid-deposits-in-anti-vascular-endothelial-growth-factor-treated-age-related-macular-degeneration
#18
Anna V Zarubina, Orly Gal-Or, Carrie E Huisingh, Cynthia Owsley, K Bailey Freund
Purpose: To explore the association between presence of subretinal drusenoid deposits (SDD) at baseline in eyes with neovascular age-related macular degeneration (nAMD) with the development of macular atrophy (MA) during anti-vascular endothelial growth factor (VEGF) therapy. Methods: There were 74 eyes without pre-existing MA receiving anti-VEGF therapy for nAMD for 2 years or longer analyzed. At least two image modalities that included spectral-domain optical coherence tomography, near-infrared reflectance, fluorescein angiography, and color fundus photos were used to assess for SDD presence, phenotype (dot and ribbon), and location, neovascularization type, and MA...
December 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29182770/field-distribution-and-density-of-culicoides-sonorensis-diptera-ceratopogonidae-eggs-in-dairy-wastewater-habitats
#19
Natalie D Wong, Emily G McDermott, Amy C Murillo, Bradley A Mullens
Culicoides sonorensis Wirth and Jones (Diptera: Ceratopogonidae) is a key bluetongue virus vector in the United States. Immatures occur in mud near the edges of wastewater ponds and are understudied targets for control efforts. Eggs of C. sonorensis were collected in the morning from a dairy wastewater pond bank by taking 5-ml surface mud samples along four transects on each of six dates. Surface mud samples parallel to waterline (10-cm long, 1-cm wide, and 0.5-cm deep) were removed at 5-cm increments ranging from 15 cm below waterline up to 25 cm above waterline...
November 22, 2017: Journal of Medical Entomology
https://www.readbyqxmd.com/read/29180885/long-term-effect-of-the-insoluble-thread-lifting-technique
#20
Mototsugu Fukaya
Background: Although the thread-lifting technique for sagging faces has become more common and popular, medical literature evaluating its effects is scarce. Studies on its long-term prognosis are particularly uncommon. Patients and methods: One hundred individuals who had previously undergone insoluble thread-lifting were retrospectively investigated. Photos in frontal and oblique views from the first and last visits were evaluated by six female individuals by guessing the patients' ages...
2017: Clinical, Cosmetic and Investigational Dermatology
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