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https://www.readbyqxmd.com/read/28096708/evaluating-medical-students-proficiency-with-a-handheld-ophthalmoscope-a-pilot-study
#1
Gregory Gilmour, James McKivigan
INTRODUCTION: Historically, testing medical students' skills using a handheld ophthalmoscope has been difficult to do objectively. Many programs train students using plastic models of the eye which are a very limited fidelity simulator of a real human eye. This makes it difficult to be sure that actual proficiency is attained given the differences between the various models and actual patients. The purpose of this article is to introduce a method of testing where a medical student must match a patient with his/her fundus photo, ensuring objective evaluation as well as developing skills on real patients which are more likely to transfer into clinical practice directly...
2017: Advances in Medical Education and Practice
https://www.readbyqxmd.com/read/28095553/evaluation-of-the-safety-and-efficacy-of-a-low-fluence-picopulsed-alexandrite-laser-in-a-pico-toning-technique-with-a-diffractive-lens-optic-for-the-treatment-of-photodamage-and-textural-improvement-in-off-the-face-applications
#2
Raminder Saluja
BACKGROUND: The diffractive optic coupled with a picosecond pulsed alexandrite laser has been shown to effectively minimize pigmen- tation while improving the appearance of textural irregularities and rhytides. We evaluated the safety and ef cacy of the diffractive optic laser treatment for off of the face applications including the hands and décolletage in a pico-toning technique. STUDY: 20 healthy female patients (40-70 years of age) were treated with a picosecond pulsed alexandrite laser with a diffractive lens...
November 1, 2016: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28063237/novel-approaches-to-the-treatment-of-bacterial-biofilm-infections
#3
REVIEW
Gareth Hughes, Mark A Webber
Bacterial infection remains a major challenge to healthcare and is responsible for significant morbidity and mortality. This situation is becoming complicated by an increasingly ageing and susceptible population and large numbers of bacterial isolates which have developed resistance to antibiotics. Bacteria which form biofilms and colonise or infect medical devices or wounds are particularly hard to treat as biofilms are inherently highly antibiotic resistant. Most infections have a component where bacteria exist as a biofilm and as a result prevention or treatment of biofilm associated infections is highly important...
January 7, 2017: British Journal of Pharmacology
https://www.readbyqxmd.com/read/28061756/a-novel-method-to-promote-physical-activity-among-older-adults-in-residential-care-an-exploratory-field-study-on-implicit-social-norms
#4
Margot A Koeneman, Astrid Chorus, Marijke Hopman-Rock, Mai J M Chinapaw
BACKGROUND: Physical activity (PA) levels of older adults living in a care setting are known to be very low. This is a significant health(care) problem, as regular PA has many health benefits also at advanced age. Research on automatic processes underlying PA behaviour in physically inactive older adults is yet non-existing. Since people are unconsciously influenced by people around them (i.e. by 'social norms') automatic processes could be used to promote PA. We developed an explorative intervention method to assess the effects of automatically processed (implicit) descriptive social norms ('What most people do') on behavioral intention and participation in PA offered in a local residential care setting...
January 6, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28034807/increased-permeability-of-reconstructed-human-epidermis-from-uvb-irradiated-keratinocytes
#5
Lilian Julia Löwenau, Christian Zoschke, Robert Brodwolf, Pierre Volz, Christian Hausmann, Suvara Wattanapitayakul, Alexander Boreham, Ulrike Alexiev, Monika Schäfer-Korting
Extrinsic (photo) aging accelerates chronologically aging in the skin due to cumulative UV irradiation. Despite recent insights into the molecular mechanisms of fibroblast aging, age-related changes of the skin barrier function have been understudied. In contrast, the constantly increasing subpopulation of aged patients causes a clinical need for effective and safe (dermatological) treatment. Herein, we reconstructed human epidermis from UVB-irradiated keratinocytes (UVB-RHE). UVB-irradiated keratinocytes show higher activity of senescence associated β-galactosidase, less cell proliferation, and reduced viability...
December 27, 2016: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/28032173/clinical-outcomes-and-complications-associated-with-fractional-lasers-a-review-of-730-patients
#6
Steven R Cohen, Ashley Goodacre, Soobin Lim, Jennifer Johnston, Cory Henssler, Brian Jeffers, Ahmad Saad, Tracy Leong
BACKGROUND: Fractional lasers were introduced to provide increased safety, while maintaining high efficacy and patient satisfaction. Patients with virtually all Fitzpatrick skin types could be safely treated using a wide spectrum of wavelengths and a broad array of skin conditions, and aging could be addressed. Although safety studies have been reported for ablative CO2 and erbium lasers, surprisingly few data are available on adverse events and complications associated with fractional lasers...
December 28, 2016: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28025730/automated-facial-recognition-of-computed-tomography-derived-facial-images-patient-privacy-implications
#7
Connie L Parks, Keith L Monson
The recognizability of facial images extracted from publically available medical scans raises patient privacy concerns. This study examined how accurately facial images extracted from computed tomography (CT) scans are objectively matched with corresponding photographs of the scanned individuals. The test subjects were 128 adult Americans ranging in age from 18 to 60 years, representing both sexes and three self-identified population (ancestral descent) groups (African, European, and Hispanic). Using facial recognition software, the 2D images of the extracted facial models were compared for matches against five differently sized photo galleries...
December 26, 2016: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
https://www.readbyqxmd.com/read/28009890/the-health-benefits-of-uv-radiation-exposure-through-vitamin-d-production-or-non-vitamin-d-pathways-blood-pressure-and-cardiovascular-disease
#8
Richard B Weller
The detrimental effects of ultraviolet radiation are well known. Skin cancer, photo-aging, and induction or exacerbation of photosensitive dermatoses have been the focus of most photobiological research since 1928 when Findlay confirmed the carcinogenicity of ultraviolet radiation using a murine model of skin cancer. The epidemiological, mechanistic and clinical trial data have enabled the classification by the International Agency for Research on Cancer of ultraviolet radiation as a Group 1 ('sufficient evidence') carcinogen for human skin...
December 23, 2016: Photochemical & Photobiological Sciences
https://www.readbyqxmd.com/read/28005755/management-of-zygomatic-fractures-in-young-patients-technical-modifications-for-aesthetic-and-functional-results
#9
Antonio Cortese, Giuseppe D'Alessio, Sergio Brongo, Maurizio Gargiulo, Pier Paolo Claudio
INTRODUCTION: The zygomaticomaxillary complex is very vulnerable to injury because of its intrinsically prominent convexity. There are 2 different surgical approaches for the therapy of these fractures: closed reduction and open reduction. In the open reduction 2 or 3 fixation points with related incisions are usually necessary in dislocated fractures: osteosynthesis must be performed starting from zygomaticofrontal suture when dislocated at this site, followed by zygomatic body fixation on the anterior sinus wall, anterior orbital floor margin fixation, and finally orbital floor reconstruction in case of eye globe dislocation with diplopia...
November 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28001455/assessment-of-efficacy-and-safety-of-a-fractionated-bipolar-radiofrequency-device-for-the-treatment-of-lower-face-wrinkles-and-laxity
#10
Yueqi Jiang, Xuting Zhang, Zhong Lu, Michael H Gold
Skin aging, as a natural course, is a gradual process. It can be classified as either intrinsic or photo-aging. In recent years, as the attention to lower face wrinkles and laxity has raised significantly, the demands to facial rejuvenation also increased, along with a variety of technologies coming into being. Fractional bipolar RF as a novel means of rejuvenation has been used in clinical practice, but questions remain in terms of its efficacy and safety. Considering a large population in our country and huge demands for skin tightening, we did this research to evaluate the efficacy and safety of fractional bipolar radiofrequency...
December 21, 2016: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/27997951/looking-for-a-location-dissociated-effects-of-event-related-plausibility-and-verb-argument-information-on-predictive-processing-in-aphasia
#11
Rebecca A Hayes, Michael Walsh Dickey, Tessa Warren
Purpose: This study examined the influence of verb-argument information and event-related plausibility on prediction of upcoming event locations in people with aphasia, as well as older and younger, neurotypical adults. It investigated how these types of information interact during anticipatory processing and how the ability to take advantage of the different types of information is affected by aphasia. Method: This study used a modified visual-world task to examine eye movements and offline photo selection...
December 1, 2016: American Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/27993192/polyphenol-enriched-vaccinium-uliginosum-l-fractions-reduce-retinal-damage-induced-by-blue-light-in-a2e-laden-arpe19-cell-cultures-and-mice
#12
Bom-Lee Lee, Jung-Hwan Kang, Hye-Mi Kim, Se-Hee Jeong, Dae-Sik Jang, Young-Pyo Jang, Se-Young Choung
Polyphenols exert beneficial effects on vision. We hypothesized that polyphenol components of Vaccinium uliginosum L. (V.U.) extract protect retinal pigment epithelial (RPE) cells against blue light-induced damage. Our aim was to test extracts containing polyphenol components to ascertain effects to reduce damage against blue light in RPEs. We measured the activity in fractions eluted from water, ethanol, and HP20 resin (FH), and found that the FH fraction had the highest beneficial activity. We isolated the individual active compounds from the FH fraction using chromatographic techniques, and found that FH contained flavonoids, anthocyanins, phenyl propanoids, and iridoids...
December 2016: Nutrition Research
https://www.readbyqxmd.com/read/27991738/down-syndrome-in-diverse-populations
#13
Paul Kruszka, Antonio R Porras, Andrew K Sobering, Felicia A Ikolo, Samantha La Qua, Vorasuk Shotelersuk, Brian H Y Chung, Gary T K Mok, Annette Uwineza, Leon Mutesa, Angélica Moresco, María Gabriela Obregon, Ogochukwu Jidechukwu Sokunbi, Nnenna Kalu, Daniel Akinsanya Joseph, Desmond Ikebudu, Christopher Emeka Ugwu, Christy A N Okoromah, Yonit A Addissie, Katherine L Pardo, J Joseph Brough, Ni-Chung Lee, Katta M Girisha, Siddaramappa Jagdish Patil, Ivy S L Ng, Breana Cham Wen Min, Saumya S Jamuar, Shailja Tibrewal, Batriti Wallang, Suma Ganesh, Nirmala D Sirisena, Vajira H W Dissanayake, C Sampath Paththinige, L B Lahiru Prabodha, Antonio Richieri-Costa, Premala Muthukumarasamy, Meow-Keong Thong, Kelly L Jones, Omar A Abdul-Rahman, Ekanem Nsikak Ekure, Adebowale A Adeyemo, Marshall Summar, Marius George Linguraru, Maximilian Muenke
Down syndrome is the most common cause of cognitive impairment and presents clinically with universally recognizable signs and symptoms. In this study, we focus on exam findings and digital facial analysis technology in individuals with Down syndrome in diverse populations. Photos and clinical information were collected on 65 individuals from 13 countries, 56.9% were male and the average age was 6.6 years (range 1 month to 26 years; SD = 6.6 years). Subjective findings showed that clinical features were different across ethnicities (Africans, Asians, and Latin Americans), including brachycephaly, ear anomalies, clinodactyly, sandal gap, and abundant neck skin, which were all significantly less frequent in Africans (P < 0...
January 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/27986527/effects-of-orbicularis-oculi-flap-anchorage-to-the-periosteum-of-the-upper-orbital-rim-on-the-lower-eyelid-position-after-transcutaneous-blepharoplasty-statistical-analysis-of-clinical-outcomes
#14
Alessandro Innocenti, Francesco Mori, Dario Melita, Emanuela Dreassi, Marco Innocenti
BACKGROUND: The aging process affects the skin, muscle, and fat of the eyes in a different manner. Their individual rejuvenation would require specific surgical treatments according to their particular demands. In the present study, we analyzed the effect of an orbicularis oculi muscle flap fixed to the superior orbital rim to prevent lower eyelid dislocation during transcutaneous blepharoplasty. METHODS: The study was conducted retrospectively comparing pre- and postoperative images of two different groups of patients: group A (20 patients) treated with an orbicularis oculi flap and group B (17 patients) treated without the flap...
November 11, 2016: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/27979482/type-i-type-iii-collagen-ratio-associated-with-diverticulitis-of-the-colon-in-young-patients
#15
Shaun R Brown, Elane M Cleveland, Corey R Deeken, Sonni S Huitron, Kanayochukwu J Aluka, Kurt G Davis
BACKGROUND: The incidence of diverticulitis in young patients is rising, whereas the type I:III collagen ratio of the colon decreases with age. Perhaps a lower type I:III collagen ratio in younger patients may predispose these patients to the development of the disease. METHOD: The purpose of this study was to evaluate the collagen content and type I:III collagen ratio in patients with diverticulitis versus a control group. Patients who underwent a colon resection were identified...
January 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/27935104/parents-reported-higher-satisfaction-rates-when-children-recognised-hospital-staff-from-photographs-placed-in-prominent-locations
#16
Shlomi Bretler, Itai Mizrachi, Anthony Luder, Yaniv Avraham, Adi Sharabi-Nov, Peter Gilbey
AIM: Improved communication with staff during a child's hospitalisation is an important determinant of family satisfaction. We examined whether displaying staff photographs in prominent locations would help children and their parents or guardians to recognise staff and whether this enhanced identification would improve parental satisfaction with their child's hospitalisation. METHODS: No photographs were displayed during the first part of the study. During the second part of the study, staff photographs were placed in prominent locations throughout the paediatric ward...
December 9, 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27927034/addressing-challenges-for-youths-with-mobility-devices-in-winter-conditions
#17
Ernesto Morales, Sally Lindsay, Geoffrey Edwards, Lori Howell, Claude Vincent, Nicole Yantzi, Véronique Gauthier
PURPOSE: Winter-related research about the experience of navigating in the urban context has mostly focused on the elderly population with physical disabilities. The aim of this project was to explore potential design solutions to enhance young people's mobility devices and the built environment to improve accessibility and participation in winter. METHODS: A multi-method qualitative design process included the following steps: (1) in-depth interviews; (2) photo elicitation; (3) individual co-design sessions; and (4) group co-design sessions (i...
December 7, 2016: Disability and Rehabilitation
https://www.readbyqxmd.com/read/27923559/nrf2-protects-photoreceptor-cells-from-photo-oxidative-stress-induced-by-blue-light
#18
Wan-Ju Chen, Caiying Wu, Zhenhua Xu, Yoshiki Kuse, Hideaki Hara, Elia J Duh
Oxidative stress plays a key role in age-related macular degeneration and hereditary retinal degenerations. Light damage in rodents has been used extensively to model oxidative stress-induced photoreceptor degeneration, and photo-oxidative injury from blue light is particularly damaging to photoreceptors. The endogenous factors protecting photoreceptors from oxidative stress, including photo-oxidative stress, are continuing to be elucidated. In this study, we evaluated the effect of blue light exposure on photoreceptors and its relationship to Nrf2 using cultured murine photoreceptor (661W) cells...
December 3, 2016: Experimental Eye Research
https://www.readbyqxmd.com/read/27913345/facial-age-estimation-with-age-difference
#19
Zhenzhen Hu, Yonggang Wen, Jianfeng Wang, Meng Wang, Richang Hong, Shuicheng Yan
Age estimation based on the human face remains a significant problem in computer vision and pattern recognition. In order to estimate an accurate age or age group of a facial image, most of the existing algorithms require a huge face data set attached with age labels. This imposes a constraint on the utilization of the immensely unlabeled or weakly labeled training data, e.g. the huge amount of human photos in the social networks. These images may provide no age label, but it is easily to derive the age difference for an image pair of the same person...
December 1, 2016: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/27886900/differential-diagnosis-of-atopic-dermatitis
#20
REVIEW
Meagan Barrett, Minnelly Luu
Atopic dermatitis (AD) is a common inflammatory condition of the skin that is usually seen in childhood, but can onset or persist into adulthood. The characteristic distribution and morphology based on age, chronic relapsing course, and pruritus comprise the clinical criteria used in the diagnosis of AD. However, the numerous morphologies ranging from acute, weeping erythematous papules to chronic lichenified plaques, can be simulated by multiple other conditions, including inflammatory, infectious, neoplastic, and photo-dermatoses...
February 2017: Immunology and Allergy Clinics of North America
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