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https://www.readbyqxmd.com/read/27869291/managing-innovation-to-maximize-value-along-the-discovery-translation-application-continuum
#1
S A Waldman, A Terzic
Success in pharmaceutical development led to a record 51 drugs approved in the past year, surpassing every previous year since 1950. Technology innovation enabled identification and exploitation of increasingly precise disease targets ensuring next generation diagnostic and therapeutic products for patient management. The expanding biopharmaceutical portfolio stands, however, in contradistinction to the unsustainable costs that reflect remarkable challenges of clinical development programs. This annual Therapeutic Innovations issue juxtaposes advances in translating molecular breakthroughs into transformative therapies with essential considerations for lowering attrition and improving the cost-effectiveness of the drug-development paradigm...
November 21, 2016: Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/27820786/self-directed-learning-in-physician-assistant-education-learning-portfolios-in-physician-assistant-programs
#2
Jeremy H Neal, Laura D M Neal
Self-directed learning (SDL) portfolios are underused in the educational process and should be considered by physician assistant (PA) programs. Clinicians such as PAs are responsible for self-identifying their learning needs, competencies, and ongoing educational requirements. This article introduces an outline for SDL in the PA profession, for direct use by learners and indirect use by educators. Without a plan, many professionals may lack the insight, motivation, and knowledge needed to improve their skill set and establish goals for individual lifelong learning...
December 2016: Journal of Physician Assistant Education
https://www.readbyqxmd.com/read/27811502/moving-nursing-program-portfolio-assessment-from-midterm-to-end-of-program-lessons-learned
#3
Kari Hickey, Jeanette Rossetti, Nancy Oldenburg, Maryann Abendroth, Connie Uhlken, Kathleen Musker, Bradley Peters, Patricia Paramore
Portfolio assessment promotes a culture of evidence, evaluates program outcomes, and provides an opportunity to assess the acquisition of knowledge and skills that are not easily assessed by examinations and other traditional assessment methods in nursing curricula. The portfolio program of 1 Midwestern school of nursing recently moved portfolio assessment to the end of program. The process of this change including logistics, rubric development, and lessons learned is highlighted.
November 1, 2016: Nurse Educator
https://www.readbyqxmd.com/read/27783428/new-curricular-design-in-biostatistics-to-prepare-residents-for-an-evidence-based-practice-and-life-long-learning-education-a-pilot-approach
#4
A Arias, O A Peters, I L Broyles
AIM: To develop, implement and evaluate an innovative curriculum in biostatistics in response to the needs of fostering critical thinking in graduate health care education for evidence-based practice and life-long learning education. METHODOLOGY: The curriculum was designed for first-year residents in a postgraduate endodontic program using a six-step approach to curriculum development to provide sufficient understanding to critically evaluate biomedical publications, to design the best research strategy to address a specific problem and to analyse data by appropriate statistical test selection...
October 26, 2016: International Endodontic Journal
https://www.readbyqxmd.com/read/27779803/developing-a-research-agenda-for-understanding-the-stigma-of-addictions-part-i-lessons-from-the-mental-health-stigma-literature
#5
REVIEW
Patrick Corrigan, Georg Schomerus, Valery Shuman, Dana Kraus, Debbie Perlick, Autumn Harnish, Magdalena Kulesza, Kathleen Kane-Willis, Sang Qin, David Smelson
BACKGROUND AND OBJECTIVES: Although advocates and providers identify stigma as a major factor in confounding the recovery of people with SUDs, research on addiction stigma is lacking, especially when compared to the substantive literature examining the stigma of mental illness. METHODS: A review of key studies from the stigma literature that yielded empirically supported concepts and methods from the mental health arena was contrasted with the much smaller and mostly descriptive findings from the addiction field...
October 25, 2016: American Journal on Addictions
https://www.readbyqxmd.com/read/27777665/the-role-of-generic-competencies-in-the-entrustment-of-professional-activities-a-nationwide-competency-based-curriculum-assessed
#6
Karsten A van Loon, Pim W Teunissen, Erik W Driessen, Fedde Scheele
BACKGROUND : Entrustable professional activities (EPAs) seek to translate essential physician competencies into clinical practice. Until now, it is not known whether EPA-based curricula offer enhanced assessment and feedback to trainees. OBJECTIVE : This study examined program directors' and senior residents' justifications for entrustment decisions and what role generic, cross-specialty competencies (such as communication skills, collaboration, and understanding health care systems) play in these decisions...
October 2016: Journal of Graduate Medical Education
https://www.readbyqxmd.com/read/27769240/feedback-using-an-eportfolio-for-medicine-long-cases-quality-not-quantity
#7
Jane Bleasel, Annette Burgess, Ruth Weeks, Inam Haq
BACKGROUND: The evidence for the positive impact of an electronic Portfolio (ePortfolio) on feedback in medicine is mixed. An ePortfolio for medical long cases in a Graduate Medical Program was developed. The purpose of this study was to explore the perceptions of medical students and faculty of the impact of the ePortfolio on the feedback process. METHODS: In total, 130 Year 3 medical students, and six faculty participated in the study. This is a mixed methods study, using a combination of both quantitative and qualitative approaches...
October 21, 2016: BMC Medical Education
https://www.readbyqxmd.com/read/27766188/healthcare-commercialization-programs-improving-the-efficiency-of-translating-healthcare-innovations-from-academia-into-practice
#8
John M Collins, Ofer Reizes, Michael K Dempsey
Academic investigators are generating a plethora of insights and technologies that have the potential to significantly improve patient care. However, to address the imperative to improve the quality, cost and access to care with ever more constrained funding, the efficiency and the consistency with which they are translated into cost effective products and/or services need to improve. Healthcare commercialization programs (HCPs) are described and proposed as an option that institutions can add to their portfolio to improve translational research...
2016: IEEE Journal of Translational Engineering in Health and Medicine
https://www.readbyqxmd.com/read/27754613/otolaryngology-residency-education-a-scoping-review-on-the-shift-towards-competency-based-medical-education
#9
N Wagner, C Fahim, K Dunn, D Reid, R R Sonnadara
BACKGROUND: Residency training programmes worldwide are experiencing a shift from the traditional time-based curriculum to competency-based medical education (CBME), due to changes in the healthcare system that have impacted clinical learning opportunities. Otolaryngology-Head and Neck Surgery (OTL-HNS) programmes are one of the first North American surgical specialties to adopt the new CBME curriculum. OBJECTIVE OF REVIEW: The purpose of this scoping review is to examine the literature pertaining to CBME in OTL-HNS programmes worldwide, to identify the tools that have been developed and identify potential barriers to the implementation of CBME...
October 18, 2016: Clinical Otolaryngology
https://www.readbyqxmd.com/read/27742179/a-guide-to-writing-academic-portfolios-for-radiologists
#10
John V Thomas, Rupan Sanyal, Janis P O'Malley, Satinder P Singh, Desiree E Morgan, Cheri L Canon
The academic educator's portfolio is a collection of materials that document academic performance and achievements, supplementing the curriculum vitae, in order to showcase a faculty member's most significant accomplishments. A decade ago, a survey of medical schools revealed frustration in the nonuniform methods of measuring faculty's medical education productivity. A proposed solution was the use of an academic educator's portfolio. In the academic medical community, compiling an academic portfolio is always a challenge because teaching has never been confined to the traditional classroom setting and often involves active participation of the medical student, resident, or fellow in the ongoing care of the patient...
October 11, 2016: Academic Radiology
https://www.readbyqxmd.com/read/27733713/pain-and-tissue-damage-in-response-to-orthodontic-tooth-movement-are-they-correlated
#11
Osmar A Cuoghi, Francielle Topolski, Lorraine P de Faria, Marcos R de Mendonça
AIM: To evaluate the correlation between pain and tissue damage in response to orthodontic tooth movement (OTM), such as hyalinization and external apical root resorption (EARR). MATERIALS AND METHODS: The literature review was used as a methodological strategy, following the knowledge development process - constructivist (ProKnow-C). Study axes were defined and keywords that best represented each axis were selected. The terms were submitted to an adherence test and validation, resulting in 12 keyword combinations...
September 1, 2016: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/27731859/undergraduate-medical-students-using-facebook-as-a-peer-mentoring-platform-a-mixed-methods-study
#12
Severin Pinilla, Leo Nicolai, Maximilian Gradel, Tanja Pander, Martin R Fischer, Philip von der Borch, Konstantinos Dimitriadis
BACKGROUND: Peer mentoring is a powerful pedagogical approach for supporting undergraduate medical students in their learning environment. However, it remains unclear what exactly peer mentoring is and whether and how undergraduate medical students use social media for peer-mentoring activities. OBJECTIVE: We aimed at describing and exploring the Facebook use of undergraduate medical students during their first 2 years at a German medical school. The data should help medical educators to effectively integrate social media in formal mentoring programs for medical students...
October 27, 2015: JMIR Medical Education
https://www.readbyqxmd.com/read/27724953/mapping-south-african-allied-health-primary-care-clinical-guideline-activity-establishing-a-stakeholder-reference-sample
#13
Janine Margarita Dizon, Karen Grimmer, Shingai Machingaidze, Pam McLaren, Quinette Louw
BACKGROUND: Little is known about allied health (AH) clinical practice guideline (CPG) activity in South Africa, and particularly in relation to primary health care (PHC). This paper reports on a scoping study undertaken to establish a reference framework, from which a comprehensive maximum variation sample could be selected. This was required to underpin robust sampling for a qualitative study aimed at understanding South African primary care AH therapy CPG activities. This paper builds on findings from the South African Guidelines Evaluation (Project SAGE) Flagship grant...
October 10, 2016: Health Research Policy and Systems
https://www.readbyqxmd.com/read/27706162/controlling-neglected-tropical-diseases-ntds-in-haiti-implementation-strategies-and-evidence-of-their-success
#14
Jean Frantz Lemoine, Anne Marie Desormeaux, Franck Monestime, Carl Renad Fayette, Luccene Desir, Abdel Nasser Direny, Sarah Carciunoiu, Lior Miller, Alaine Knipes, Patrick Lammie, Penelope Smith, Melissa Stockton, Lily Trofimovich, Kalpana Bhandari, Richard Reithinger, Kathryn Crowley, Eric Ottesen, Margaret Baker
Lymphatic filariasis (LF) and soil-transmitted helminths (STH) have been targeted since 2000 in Haiti, with a strong mass drug administration (MDA) program led by the Ministry of Public Health and Population and its collaborating international partners. By 2012, Haiti's neglected tropical disease (NTD) program had reached full national scale, and with such consistently good epidemiological coverage that it is now able to stop treatment for LF throughout almost all of the country. Essential to this success have been in the detail of how MDAs were implemented...
October 2016: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/27684613/clinical-data-systems-to-support-public-health-practice-a-national-survey-of-software-and-storage-systems-among-local-health-departments
#15
J Mac McCullough, Kate Goodin
CONTEXT: Numerous software and data storage systems are employed by local health departments (LHDs) to manage clinical and nonclinical data needs. Leveraging electronic systems may yield improvements in public health practice. However, information is lacking regarding current usage patterns among LHDs. OBJECTIVE: To analyze clinical and nonclinical data storage and software types by LHDs. DESIGN: Data came from the 2015 Informatics Capacity and Needs Assessment Survey, conducted by Georgia Southern University in collaboration with the National Association of County and City Health Officials...
November 2016: Journal of Public Health Management and Practice: JPHMP
https://www.readbyqxmd.com/read/27671458/impact-of-integrated-vascular-residencies-on-academic-productivity-within-vascular-surgery-divisions
#16
Bradford J Kim, Nakul P Valsangkar, Tiffany W Liang, Michael P Murphy, Teresa A Zimmers, Teresa M Bell, Mark G Davies, Leonidas G Koniaris
BACKGROUND: Changing training paradigms in vascular surgery have been introduced to reduce overall training time. Herein, we sought to examine how shortened training for vascular surgeons may have influenced overall divisional academic productivity. METHODS: Faculty from the top 55 surgery departments were identified according to National Institutes of Health (NIH) funding. Academic metrics of 315 vascular surgery, 1,132 general surgery, and 2,403 other surgical specialties faculty were examined using institutional Web sites, Scopus, and NIH Research Portfolio Online Reporting Tools from September 1, 2014, to January 31, 2015...
September 23, 2016: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/27651056/an-innovative-no-cost-evidence-based-smartphone-platform-for-resident-evaluation
#17
REVIEW
John M Green
PURPOSE: Timely performance evaluation and feedback are critical to resident development. However, formulating and delivering this information disrupts physician workflow, leading to low participation. This study was designed to determine if a locally developed smartphone platform would integrate regular evaluation into daily processes and thus increase faculty participation in timely resident evaluation. METHODS: Formal, documented resident operative and patient interaction evaluations were compiled over an 8-month study period...
November 2016: Journal of Surgical Education
https://www.readbyqxmd.com/read/27646870/embedding-of-the-progress-test-in-an-assessment-program-designed-according-to-the-principles-of-programmatic-assessment
#18
Sylvia Heeneman, Suzanne Schut, Jeroen Donkers, Cees van der Vleuten, Arno Muijtjens
BACKGROUND: Progress tests (PT) are used to assess students on topics from all medical disciplines. Progress testing is usually one of the assessment methods of the cognitive domain. There is limited knowledge on how positioning of the PT in a program of assessment (PoA) influences students' PT scores, use of PT feedback and perceived learning value. METHODS: We compared PT total scores and use of a PT test feedback (ProF) system in two medical courses, where the PT is either used as a summative assessment or embedded in a comprehensive PoA and used formatively...
September 19, 2016: Medical Teacher
https://www.readbyqxmd.com/read/27619249/radiation-therapeutic-agent-clinical-trials-leveraging-advantages-of-a-national-cancer-institute-programmatic-collaboration
#19
REVIEW
Naoko Takebe, Mansoor M Ahmed, Bhadrasain Vikram, Eric J Bernhard, James Zwiebel, C Norman Coleman, Charles A Kunos
A number of oncology phase II radiochemotherapy trials with promising results have been conducted late in the overall experimental therapeutic agent development process. Accelerated development and approval of experimental therapeutic agents have stimulated further interest in much earlier radiation-agent studies to increase the likelihood of success in phase III trials. To sustain this interest, more forward-thinking preclinical radiobiology experimental designs are needed to improve discovery of promising radiochemotherapy plus agent combinations for clinical trial testing...
October 2016: Seminars in Radiation Oncology
https://www.readbyqxmd.com/read/27606781/poly-victimization-and-resilience-portfolios-trends-in-violence-research-that-can-enhance-the-understanding-and-prevention-of-elder-abuse
#20
Sherry Hamby, Alli Smith, Kimberly Mitchell, Heather Turner
This literature review assesses the current state of knowledge about elder abuse and mistreatment, focusing on the lack of incorporation of all forms of elder victimization and the benefits of a poly-victimization framework. This review also includes existing knowledge on risk factors and calls for a greater focus on protective factors and a greater inclusion on family and community factors. Future research, prevention, and intervention would benefit from considering the true burden of elder victimization and a greater implementation of strengths-based approaches to programs...
September 8, 2016: Journal of Elder Abuse & Neglect
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