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https://www.readbyqxmd.com/read/28804921/serum-thymidine-kinase-1-canine-c-reactive-protein-haptoglobin-and-vitamin-d-concentrations-in-dogs-with-immune-mediated-hemolytic-anemia-thrombocytopenia-and-polyarthropathy
#1
M Grobman, H Outi, H Rindt, C Reinero
BACKGROUND: Relapses of immune-mediated hemolytic anemia (IMHA), thrombocytopenia (ITP), or polyarthropathy (IMPA) occur despite normal hematologic and cytologic parameters. Thymidine kinase 1 (TK1), canine C-reactive protein (c-CRP), haptoglobin (HPT), and 25-Hydroxyvitamin-D (25(OH)D) might be adjunct to current monitoring strategies. HYPOTHESIS/OBJECTIVES: Compare serum concentrations of TK1, c-CRP, HPT, and 25(OH)D in dogs with well- and poorly controlled primary IMHA, ITP, or IMPA...
August 14, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28804727/development-of-a-prediction-model-for-stress-fracture-during-an-intensive-physical-training-program-the-royal-marines-commandos
#2
Maria T Sanchez-Santos, Trish Davey, Kirsten M Leyland, Adrian J Allsopp, Susan A Lanham-New, Andrew Judge, Nigel K Arden, Joanne L Fallowfield
BACKGROUND: Stress fractures (SFs) are one of the more severe overuse injuries in military training, and therefore, knowledge of potential risk factors is needed to assist in developing mitigating strategies. PURPOSE: To develop a prediction model for risk of SF in Royal Marines (RM) recruits during an arduous military training program. STUDY DESIGN: Case-control study; Level of evidence, 3. METHODS: RM recruits (N = 1082; age range, 16-33 years) who enrolled between September 2009 and July 2010 were prospectively followed through the 32-week RM training program...
July 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28803880/vitamin-d-and-symptoms-of-depression-in-overweight-or-obese-adults-a-cross-sectional-study-and-randomized-placebo-controlled-trial
#3
Aya Mousa, Negar Naderpoor, Maximilian P J de Courten, Barbora de Courten
Recent evidence suggests that vitamin D deficiency may contribute to increased risk of depression. However, previous studies are limited by variability in participant characteristics including vitamin D deficiency status and presence of existing diseases, use of low doses of vitamin D supplementation for short durations, and use of co-interventions or psychotropic drugs. We examined whether 25-hydroxyvitamin D (25(OH)D) concentrations were associated with symptoms of depression, as well as whether vitamin D supplementation reduced symptoms of depression in overweight or obese and vitamin D-deficient, but otherwise healthy adults...
August 10, 2017: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/28802294/serum-25-hydroxyvitamin-d-and-elderly-skeletal-muscle-mass-and-function-in-urban-north-china
#4
Liping Meng, Qingqing Man, Linhong Yuan, Lingxia Shen, Weimin Li, Guiyuan Guo, Lixiang Li, Shanshan Jia, Yixiong Gao, Pengkun Song, Jian Zhang
BACKGROUND AND OBJECTIVES: To investigate the association of serum 25-hydroxyvitamin D (25(OH)D) with skeletal muscle mass (SMM) and function among the elderly in an urban area in northern China. METHODS AND STUDY DESIGN: A total of 912 participants (316 men, 596 women) aged more than 60 years from 4 communities in Beijing were enrolled. Serum concentrations of 25(OH)D were measured through radioimmunoassay. SMM was assessed through bioelectrical impendence analysis, whereas skeletal muscle function was assessed through grip strength and 4-m regular gait speed measurements...
2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28801201/effectiveness-of-controlled-telescoping-system-for-lateral-hip-pain-caused-by-sliding-of-blade-following-intramedullary-nailing-of-trochanteric-fracture
#5
Suk Kyu Choo, Hyoung-Keun Oh, Hyeong Tak Ko, Dong-Uk Min, Youngwoo Kim
INTRODUCTION: The purpose of this study was to demonstrate the effectiveness of controlled telescoping system for lateral hip pain caused by sliding of the blade following intramedullary nailing of trochanteric fractures. MATERIALS AND METHODS: A retrospective cohort study was performed to compare the controlled telescoping system (Compression Hip Nail; CHN) with the conventional sliding system (Proximal Femoral Nail Antirotation; PFNA) for trochanteric fractures...
July 25, 2017: Injury
https://www.readbyqxmd.com/read/28800671/-outcomes-of-planned-out-of-hospital-and-low-risk-hospital-births-in-lower-saxony
#6
Antje Petersen, Lea-Marie Köhler, Christiane Schwarz, Bernhard Vaske, Mechthild M Gross
Introduction Internationally, there is debate on the safety of different birth settings inside and outside of hospitals. Low-risk women in Germany can choose where they give birth, and out-of-hospital births are especially necessary in regions lacking infrastructure. To date, national studies are required. Materials and Methods We investigated planned out-of-hospital (OH) and hospital births in Lower Saxony, Germany, in 2005. Women with a singleton fetus in the vertex position were included once they reached 34+0 gestational weeks...
August 2017: Zeitschrift Für Geburtshilfe und Neonatologie
https://www.readbyqxmd.com/read/28800425/implementing-the-adapted-physical-education-e-learning-program-into-physical-education-teacher-education-program
#7
Eun Hye Kwon, Martin E Block
According to the Ministry of Education Korea (2014), the approximately 70.4% of all students with disabilities are included in general schools in Korea. However, studies show that Korean GPE teachers do not feel comforatble or prepared to include students with disabilities (Oh & Lee, 1999; Roh, 2002; Roh & Oh, 2005). The purpose of this study was to explore whether an APE e-learning supplement would have an impact on the level of self-efficacy and content knowledge of pre-service teachers related to including students with intellectual disabilities...
August 8, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/28800394/zno-101-%C3%AC-0-surface-hydroxylation-under-ambient-water-vapor
#8
John T Newberg, Chris Goodwin, Chris Arble, Yehia Khalifa, Jorge Anibal Boscoboinik, Sana Rani
The interaction of water vapor with a single crystal ZnO(101 ̅0) surface was investigated using synchrotron-based ambient pressure X-ray photoelectron spectroscopy (APXPS). Two isobaric experiments were performed at 0.3 and 0.07 Torr water vapor pressure at sample temperatures ranging from 750 K to 295 K up to a maximum of 2 % relative humidity (RH). Below 10-4 % RH the ZnO(101 ̅0) interface is covered with ~0.25 monolayers of OH groups attributed to dissociation at non-stoichiometric defect sites. At ~10-4 % RH there is sharp onset in increased surface hydroxylation attributed to reaction at stoichiometric terrace sites...
August 11, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28799838/vitamin-d-receptor-gene-foki-polymorphism-in-egyptian-children-and-adolescents-with-sle-a-case-control-study
#9
A A Imam, H E Ibrahim, M A A Farghaly, U M Alkholy, H H Gawish, N Abdalmonem, A M Sherif, Y F Ali, M E Hamed, N M Waked, M M Fathy, A M Khalil, M A Noah, M S Hegab, B R Ibrahim, R M Nabil, L A Fattah
Background Childhood-onset systemic lupus erythematosus (cSLE) is a lifelong autoimmune disorder. The vitamin D receptor (VDR) gene is a potential candidate gene for cSLE susceptibility. In this study, we aimed to investigate the FokI polymorphism in the VDR gene in Egyptian children and adolescents with SLE, to determine whether this polymorphism could be a genetic marker for cSLE susceptibility or disease activity and we also measured the serum level of 25-hydroxyvitamin D [25(OH) D] to assess its relation to such polymorphism...
January 1, 2017: Lupus
https://www.readbyqxmd.com/read/28799812/high-prevalence-of-vitamin-d-deficiency-in-patients-with-bone-tumors
#10
Konstantin Horas, Gerrit Maier, Franz Jakob, Uwe Maus, Andreas Kurth, Axel Jakuscheit, Maximilian Rudert, Boris Michael Holzapfel
The aim of this study was to evaluate the prevalence of vitamin D deficiency in patients with different types of bone tumors and to elucidate whether or not there are differences in prediagnostic vitamin D levels in patients with malignant compared to benign bone tumors. Prediagnostic serum 25(OH)D levels of 105 consecutive patients that presented with bone tumors and tumor-like lesions to two Orthopedic Level I University Centers in Germany between 2011 and 2016 were measured on admission. We found an alarming and widespread rate of vitamin D deficiency in patients with bone tumors...
August 11, 2017: Cancer Investigation
https://www.readbyqxmd.com/read/28799031/spirosoma-metallum-sp-nov-isolated-from-an-automobile-air-conditioning-system
#11
Dong-Uk Kim, Hyosun Lee, Suyeon Lee, Sooyeon Park, Jung-Hoon Yoon, So Yoon Park, Jong-Ok Ka
A Gram-stain-negative and yellow-pigmented bacterial strain, designated TX0653(T), was isolated from an automobile evaporator core collected in Korea. The cells were aerobic and rod-shaped. The strain grew at 10-28 °C (optimum, 25 °C), at pH 6.0-7.5 (optimum, 6.5), and in the presence of 0-1% (w/v) NaCl (optimum, 0%). Phylogenetically, the strain was related to members of the genus Spirosoma (95.1-90.8% 16S rRNA sequence similarity) and distantly related to Spirosoma pulveris JSH5-14(T) (95.1%), Spirosoma fluviale MSd3(T) (95...
August 10, 2017: Archives of Microbiology
https://www.readbyqxmd.com/read/28798934/comparative-phenotype-and-genome-analysis-of-cellvibrio-sp-pr1-a-xylanolytic-and-agarolytic-bacterium-from-the-pearl-river
#12
Zhangzhang Xie, Weitie Lin, Jianfei Luo
Cellvibrio sp. PR1 is a xylanolytic and agarolytic bacterium isolated from the Pearl River. Strain PR1 is closely related to Cellvibrio fibrivorans and C. ostraviensis (identity > 98%). The xylanase and agarase contents of strain PR1 reach up to 15.4 and 25.9 U/mL, respectively. The major cellular fatty acids consisted of C16:0 (36.7%), C18:0 (8.8%), C20:0 (6.8%), C15:0 iso 2-OH or/and C16:1ω7c (17.4%), and C18:1ω7c or/and C18:1ω6c (6.7%). A total of 251 CAZyme modules (63 CBMs, 20 CEs, 128 GHs, 38 GTs, and 2 PLs) were identified from 3,730 predicted proteins...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28798736/escherichia-coli-o157-h7-acid-sensitivity-correlates-with-flocculation-phenotype-during-nutrient-limitation
#13
Kathryn L Kay, Frederick Breidt, Pina M Fratamico, Gian M Baranzoni, Gwang-Hee Kim, Amy M Grunden, Deog-Hwan Oh
Shiga toxin producing Escherichia coli (STEC) strains vary in acid resistance; however, little is known about the underlying mechanisms that result in strain specific differences. Among 25 STEC O157:H7 strains tested, 7 strains flocculated when grown statically for 18 h in minimal salts medium at 37°C, while 18 strains did not. Interestingly, the flocculation phenotype (cells came out of suspension) was found to correlate with degree of acid sensitivity in an assay with 400 mM acetic acid solution at pH 3...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28798354/enpp1-is-an-anti-aging-factor-that-regulates-klotho-under-phosphate-overload-conditions
#14
Ryuichi Watanabe, Nobuyuki Fujita, Yuiko Sato, Tami Kobayashi, Mayu Morita, Takatsugu Oike, Kana Miyamoto, Makoto Kuro-O, Toshimi Michigami, Seiji Fukumoto, Takashi Tsuji, Yoshiaki Toyama, Masaya Nakamura, Morio Matsumoto, Takeshi Miyamoto
Control of phosphate metabolism is crucial to regulate aging in mammals. Klotho is a well-known anti-aging factor that regulates phosphate metabolism: mice mutant or deficient in Klotho exhibit phenotypes resembling human aging. Here we show that ectonucleotide pyrophosphatase/phosphodiesterase 1 (Enpp1) is required for Klotho expression under phosphate overload conditions. Loss-of-function Enpp1 (ttw/ttw) mice under phosphate overload conditions exhibited phenotypes resembling human aging and Klotho mutants, such as short life span, arteriosclerosis and osteoporosis, with elevated serum 1,25(OH)2D3 levels...
August 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28798036/why-don-t-serum-vitamin-d-concentrations-associate-with-bmd-by-dxa-a-case-of-being-bound-to-the-wrong-assay-implications-for-vitamin-d-screening
#15
Richard J Allison, Abdulaziz Farooq, Anissa Cherif, Bruce Hamilton, Graeme L Close, Mathew G Wilson
BACKGROUND: The association between bone mineral density (BMD) and serum25-hydroxyvitamin D (25(OH)D) concentration is weak, particularly in certain races (eg, BlackAfrican vs Caucasian) and in athletic populations. We aimed to examine if bioavailable vitamin D rather than serum 25(OH)D was related to markers of bone health within a racially diverse athletic population. METHODS: In 604 male athletes (Arab (n=327), Asian (n=48), Black(n=108), Caucasian (n=53)and Hispanic (n=68)), we measured total 25(OH)D, vitamin D-binding protein and BMD by DXA...
August 10, 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/28797922/vitamin-d-receptor-expression-and-potential-role-of-vitamin-d-on-cell-proliferation-and-steroidogenesis-in-goat-ovarian-granulosa-cells
#16
Xiaolei Yao, Guomin Zhang, Yixuan Guo, Mohamed Ei-Samahy, Shuting Wang, Yongjie Wan, Le Han, Zifei Liu, Feng Wang, Yanli Zhang
This study aimed to investigate the expression of the vitamin D receptor (VDR) in goat follicles and to determine the effects of Vit D3 supplementation on goat granulosa cells (GCs) function linked to follicular development. The results demonstrated that VDR was prominently localized in GCs, with expression increasing with follicle diameter. Addition of Vit D3 (1α,25-(OH)2VD3; 10 nM) to GCs caused an increase in VDR and in steroidogenic acute regulator (StAR) and 3β-hydroxysteroid dehydrogenase (3β-HSD) mRNA expression...
August 3, 2017: Theriogenology
https://www.readbyqxmd.com/read/28797353/clinical-outcomes-with-a-repositionable-self-expanding-transcatheter-aortic%C3%A2-valve%C3%A2-prosthesis-the-international-forward-study
#17
Eberhard Grube, Nicolas M Van Mieghem, Sabine Bleiziffer, Thomas Modine, Johan Bosmans, Ganesh Manoharan, Axel Linke, Werner Scholtz, Didier Tchétché, Ariel Finkelstein, Ramiro Trillo, Claudia Fiorina, Antony Walton, Christopher J Malkin, Jae K Oh, Hongyan Qiao, Stephan Windecker
BACKGROUND: Clinical outcomes in large patient populations from real-world clinical practice with a next-generation self-expanding transcatheter aortic valve are lacking. OBJECTIVES: This study sought to document the clinical and device performance outcomes of transcatheter aortic valve replacement (TAVR) with a next-generation, self-expanding transcatheter heart valve (THV) system in patients with severe symptomatic aortic stenosis (AS) in routine clinical practice...
August 15, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28797319/baseline-assessment-of-25-hydroxyvitamin-d-reference-material-and-proficiency-testing-external-quality-assurance-material-commutability-a-vitamin-d-standardization-program-study
#18
Karen Phinney, Christopher Sempos, Susan Tai, Johanna Camara, Stephen Wise, John Eckfeldt, Andrew Hoofnagle, Graham Carter, Julia Jones, Gary Myers, Ramon Durazo-Arvizu, W Greg Miller, Lorin Bachmann, Ian Young, Juanita Pettit, Andrew Liu, Stephen Brooks, Kurtis Sarafin, Michael Thamm, Gert Mensink, Markus Busch, Martina Rabenberg, Kevin Cashman, Mairead Kiely, Karen Galvin, Joy Zhang, Michael Kinsella, Kyungwon Oh, Sun-Wha Lee, Chae Jung, Lorna Cox, Gail Goldberg, Kate Guberg, Sarah Meadows, Ann Prentice, Lu Tian, Patsy Brannon, Robyn Lucas, Peter Crump, Etienne Cavalier, Joyce Merkel, Joseph Betz, Grahame Caldwell
The Vitamin D Standardization Program (VDSP) coordinated a study in 2012 to assess the commutability of reference materials and proficiency testing/external quality assurance materials for total 25-hydroxyvitamin D [25(OH)D] in human serum, the primary indicator of vitamin D status. A set of 50 single-donor serum samples as well as 17 reference and proficiency testing/external quality assessment materials were analyzed by participating laboratories that used either immunoassay or LC-MS methods for total 25(OH)D...
August 10, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/28797019/associations-of-low-vitamin-d-and-elevated-parathyroid-hormone-concentrations-with-bone-mineral-density-in-perinatally-hiv-infected-children
#19
Denise L Jacobson, Charles B Stephensen, Tracie L Miller, Kunjal Patel, Janet S Chen, Russell B Van Dyke, Ayesha Mirza, Gertrud U Schuster, Rohan Hazra, Angela Ellis, Sean S Brummel, Mitchell E Geffner, Margarita Silio, Stephen A Spector, Linda A DiMeglio
BACKGROUND: Perinatally HIV-infected (PHIV) children have, on average, lower bone mineral density (BMD) than perinatally HIV-exposed uninfected (PHEU) and healthy children. Low 25-hydroxy vitamin D [25(OH)D] and elevated parathyroid hormone (PTH) concentrations may lead to suboptimal bone accrual. METHODS: PHIV and PHEU children in the Pediatric HIV/AIDS Cohort Study had total body (TB) and lumbar spine (LS) BMD and bone mineral content (BMC) measured by dual-energy x-ray absorptiometry; BMD z-scores (BMDz) were calculated for age and sex...
September 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28796426/vitamin-d-levels-in-smith-lemli-opitz-syndrome
#20
Miyad Movassaghi, Simona Bianconi, Richard Feinn, Christopher A Wassif, Forbes D Porter
Smith-Lemli-Opitz syndrome (SLOS) is an autosomal recessive congenital malformation syndrome caused by mutations in the 7-dehydrocholesterol reductase gene. This inborn error of cholesterol synthesis leads to elevated concentrations of 7-dehydrocholesterol (7-DHC). 7-DHC also serves as the precursor for vitamin D synthesis. Limited data is available on vitamin D levels in individuals with SLOS. Due to elevated concentrations of 7-DHC, we hypothesized that vitamin D status would be abnormal and possibly reach toxic levels in patients with SLOS...
August 10, 2017: American Journal of Medical Genetics. Part A
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