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https://www.readbyqxmd.com/read/29458121/the-paradox-of-marrow-adipose-tissue-in-anorexia-nervosa
#1
Pouneh K Fazeli, Anne Klibanski
Anorexia nervosa (AN) is a psychiatric disorder characterized by inappropriate nutrient intake resulting in low body weight. Multiple hormonal adaptations facilitate decreased energy expenditure in this state of caloric deprivation including non-thyroidal illness syndrome, growth hormone resistance, and hypogonadotropic hypogonadism. Although these hormonal adaptations confer a survival advantage during periods of negative energy balance, they contribute to the long-term medical complications associated with AN, the most common of which is significant bone loss and an increased risk of fracture...
February 16, 2018: Bone
https://www.readbyqxmd.com/read/29457980/probing-the-chemistry-of-adhesion-between-a-316l-substrate-and-spin-on-glass-coating
#2
Felix Lampert, Shima Kadkhodazadeh, Takeshi Kasama, Kristian Vinter Dahl, Alexander Bruun Christiansen, Per Møller
Hydrogen silsesquioxane ([HSiO3/2]n) based "spin-on-glass" has been deposited on 316L substrate and cured in Ar/H2 gas atmosphere at 600 ºC to form a continuous surface coating with sub-micrometer thickness. The coating functionality depends primarily on the adhesion to the substrate, which is largely affected by the chemical interaction at the interface between the coating and the substrate. We have investigated this interface by transmission electron microscopy and electron energy loss spectroscopy...
February 19, 2018: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29457780/comment-on-nanoscale-mapping-of-optical-band-gaps-using-monochromated-electron-energy-loss-spectroscopy-by-zhan-graner%C3%A3-d-venkatachalapathy-johansen-jensen-kuznetsov-and-prytz-in-nanotechnology-28-2017-105703
#3
Thomas Walther
Comment on ‘Nanoscale mapping of optical band gaps using monochromated electron energy loss spectroscopy’ by Zhan, Granerød, Venkatachalapathy, Johansen, Jensen, Kuznetsov and Prytz in Nanotechnology 28 (2017) 105703 
 by 
 Thomas Walther, Department,of Electronic & Electrical Enginenering, University of Sheffield, Sheffield, UK.
February 19, 2018: Nanotechnology
https://www.readbyqxmd.com/read/29457710/investigation-of-%C3%AE-mno-2-tunneled-structures-as-model-cation-hosts-for-energy-storage
#4
Lisa M Housel, Lei Wang, Alyson Abraham, Jianping Huang, Genesis D Renderos, Calvin D Quilty, Alexander B Brady, Amy C Marschilok, Kenneth J Takeuchi, Esther S Takeuchi
Future advances in energy storage systems rely on identification of appropriate target materials and deliberate synthesis of the target materials with control of their physiochemical properties in order to disentangle the contributions of distinct properties to the functional electrochemistry. This goal demands systematic inquiry using model materials that provide the opportunity for significant synthetic versatility and control. Ideally, a material family that enables direct manipulation of characteristics including composition, defects, and crystallite size while remaining within the defined structural framework would be necessary...
February 19, 2018: Accounts of Chemical Research
https://www.readbyqxmd.com/read/29457709/hybrid-donor-acceptor-polymer-particles-with-amplified-energy-transfer-for-detection-and-on-demand-treatment-of-breast-cancer
#5
Elizabeth G Graham-Gurysh, Sneha Kelkar, Eleanor McCabe-Lankford, Narayanan Kuthirummal, Theodore Brown, Nancy Kock, Aaron M Mohs, Nicole Levi-Polyachenko
Judicious combination of semiconducting polymers with alternating electron donor (D) and acceptor (A) segments created hybrid nanoparticles with amplified energy transfer and red-shifted emission, while simultaneously providing photothermal capabilities. Hybrid D-A polymer particles (H-DAPPs) passively localized within orthotopic breast tumors, serving as bright fluorescent beacons. Laser stimulation induced heat generation on par with gold nanorods, resulting in selective destruction of the tumor. H-DAPPs can also undergo multiple thermal treatments, with no loss of fluorescence intensity or photothermal potential...
February 19, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29457163/probing-energy-losses-from-dye-desorption-in-cobalt-complex-based-dye-sensitized-solar-cells
#6
Yan Zhang, Yungen Wu, Zhe Sun, Yanan Kang, Tianyang Chen, Hui Wang, Mao Liang, Song Xue
Self-assembly of organic sensitizer layers in cobalt complex-based DSCs was studied to elucidate its role in reducing the loss of charge recombination. DSCs with various dye loadings were fabricated by dye desorption without the aid of basic solvent. The FT-IR and UV results indicate the deprotonation of the anchoring organic sensitizers, which influences the conduction band of TiO2 remarkably by changing the surface potential. Positive band edge shifts and a decrease of the recombination rate constant are demonstrated to be the main factors affecting energy loss at open circuit...
February 19, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29455119/developing-a-safety-heatmap-of-uncontrolled-intersections-using-both-conflict-probability-and-severity
#7
Yingying Ma, Xiaoran Qin, Offer Grembek, Zhiwei Chen
This paper presents a method to assess the safety of uncontrolled intersections considering two major properties of traffic conflicts-conflict probability and severity. This method assesses both the safety level of the entire intersection in addition to the distribution of safety within it. Intersections are modeled by a two-dimensional Cartesian coordinate system and the internal space of intersections is divided into cells. First, the vehicle movement characteristics of an uncontrolled intersection are modeled...
February 15, 2018: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/29454318/points-based-physical-activity-a-novel-approach-to-facilitate-changes-in-body-composition-in-inactive-women-with-overweight-and-obesity
#8
Adrian Holliday, Alice Burgin, Elyzabeth Vargas Fernandez, Sally A M Fenton, Frank Thielecke, Andrew K Blannin
BACKGROUND: Physical activity (PA) interventions for the promotion of weight-management may benefit from increased choice and flexibility to overcome commonly-perceived barriers to PA. The aim of this study was to investigate the effects of a novel "points-based" approach to PA on body composition in inactive women, who are overweight or obese. METHODS: Seventy-six overweight or obese, inactive women were randomly allocated to one of three conditions: 'Points-based' PA (PBPA; 30 "PA points"•week- 1 ), Structured exercise (StructEx; 150 min moderate-intensity exercise•week- 1 ) or control (CONT; continue habitual inactive lifestyle) for a 24-week intervention...
February 17, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29454266/simplified-bernoulli-formula-to-predict-flow-limiting-stenosis-at-coronary-computed-tomography-angiography
#9
Nobuo Tomizawa, Kodai Yamamoto, Shinichi Inoh, Takeshi Nojo, Sunao Nakamura
OBJECTIVE: To compare the diagnostic performance of estimated energy loss (EEL) with diameter stenosis (DS) to estimate significant stenosis by fractional flow reserve (FFR). MATERIALS AND METHODS: One hundred twenty-five patients were included. EEL was calculated using DS, lesion length, minimal lumen area and left ventricular volume. FFR ≤ 0.80 was determined significant. RESULTS: EEL improved the accuracy from 63% (95% confidence interval (CI): 55-72%) to 83% (95% CI: 75-89%, p < 0...
February 6, 2018: Clinical Imaging
https://www.readbyqxmd.com/read/29454140/weight-management-in-rural-health-clinics-the-midwest-diet-and-exercise-trial
#10
Anna M Gorczyca, Richard A Washburn, Lauren Ptomey, Matthew S Mayo, Debra K Sullivan, Cheryl A Gibson, Robert Lee, Sarah Stolte, Joseph E Donnelly
Obesity prevalence is higher in rural compared to urban residents. Rural health clinics offer a potential venue for delivery of weight management. However, traditional programs require travel to attend on-site meetings which is impractical or inconvenient for rural residents. Clinic staff in most rural settings are unlikely to be trained to provide effective weight management. Remote delivery using group phone conferences (GP) or individual phone calls (IP), by staff associated with rural clinics eliminates the need for travel to attend on-site meetings...
February 14, 2018: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/29453899/the-role-of-dna-pk-in-aging-and-energy-metabolism
#11
REVIEW
Jay H Chung
DNA-dependent protein kinase (DNA-PK) is a very large holoenzyme comprised of the p470 kDa DNA-PK catalytic subunit (DNA-PKcs ) and the Ku heterodimer consisting of the p86 (Ku 80) and p70 (Ku 70) subunits. It is best known for its non-homologous end joining (NHEJ) activity, which repairs double-strand DNA (dsDNA) breaks (DSBs). As expected, the absence of DNA-PK activity results in sensitivity to ionizing radiation, which generates DSBs and defect in lymphocyte development, which requires NHEJ of the V(D)J region in the immunoglobulin and T cell receptor loci...
February 17, 2018: FEBS Journal
https://www.readbyqxmd.com/read/29453683/flow-energy-loss-as-a-predictive-parameter-for-right-ventricular-deterioration-caused-by-pulmonary-regurgitation-after-tetralogy-of-fallot-repair
#12
Miyuki Shibata, Keiichi Itatani, Taiyu Hayashi, Takashi Honda, Atsushi Kitagawa, Kagami Miyaji, Minoru Ono
The optimal timing for pulmonary valve replacement after Tetralogy of Fallot (TOF) repair remains controversial. In this study, we estimated the feasibility of using flow energy loss (FEL) to predict right ventricular (RV) deterioration due to pulmonary regurgitation after TOF repair. We examined RV outflow tract (RVOT) flow in nine patients who underwent TOF or double-outlet right ventricle repair in the intervention group (Group I) and compared them with three healthy children in the control group (Group C)...
February 16, 2018: Pediatric Cardiology
https://www.readbyqxmd.com/read/29453322/the-mtor-targets-4e-bp1-2-restrain-tumor-growth-and-promote-hypoxia-tolerance-in-pten-driven-prostate-cancer
#13
Mei Ding, Theodorus H van der Kwast, Ravi N Vellanki, Warren D Foltz, Trevor D McKee, Nahum Sonenberg, Pier Paolo Pandolfi, Marianne Koritzinsky, Bradly G Wouters
The mTOR signaling pathway is a central regulator of protein synthesis and cellular metabolism in response to the availability of energy, nutrients, oxygen, and growth factors. mTOR activation leads to phosphorylation of multiple downstream targets including the eukaryotic initiation factor 4E (eIF4E) binding proteins-1 and -2 (EIF4EBP1/4E-BP1 and EIF4EBP2/4E-BP2). These binding proteins inhibit protein synthesis, but are inactivated by mTOR to stimulate cell growth and metabolism. However, the role of these proteins in the context of aberrant activation of mTOR, which occurs frequently in cancers through loss of PTEN or mutational activation of the PI3K/AKT pathway, is unclear...
February 16, 2018: Molecular Cancer Research: MCR
https://www.readbyqxmd.com/read/29452452/-effectivity-and-safety-of-a-modified-tip-design-in-torsional-phacoemulsification
#14
Sabine Schmidt, Sophie Hubich, Jan Markus Vetter, Christopher Wirbelauer
BACKGROUND: Torsional mode phacoemulsification results in more effective fragmentation of the nucleus due to a different movement of the phacotip. In this clinical study, we investigated the influence of a modified tip design and active fluidics on the efficacy of phacoemulsification and safety for the corneal endothelium. MATERIAL AND METHODS: We conducted a prospective randomized 2 : 1 study in which 40 patients were operated on with the mini-flared Kelman Tip using the Infiniti ® System (group 1), and 20 patients were operated on with the Intrepid ® Balanced Tip and the Centurion ® System...
February 16, 2018: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/29451982/photodissociation-of-the-cyclopentadienyl-radical-at-248-nm
#15
Mark Shapero, Isaac A Ramphal, Daniel M Neumark
The photodissociation of jet-cooled cyclopentadienyl radicals, c-C 5 H 5 , at 248 nm has been studied using photofragment translational spectroscopy. Two dissociation channels were observed, H + C 5 H 4 and C 3 H 3 + C 2 H 2 . The C 5 H 4 fragment was identified as ethynylallene by its ionization energy. The translational energy distribution determined for each channel suggests that both dissociation mechanisms occur via internal conversion to the ground electronic state followed by intramolecular vibrational redistribution and dissociation...
February 16, 2018: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/29450584/dietary-patterns-and-longitudinal-change-in-hip-bone-mineral-density-among-older-men
#16
T S Rogers, S Harrison, S Judd, E S Orwoll, L M Marshall, J Shannon, L Langsetmo, N E Lane, J M Shikany
Studying dietary patterns is often more informative than individual nutrients or foods. We found that a Prudent dietary pattern (rich in vegetables and fish) was associated with reduced loss of total hip BMD in older men. A Prudent dietary pattern may be a potential lifestyle strategy for minimizing bone loss. INTRODUCTION: This study aimed to identify baseline dietary patterns using factor analysis in a cohort of older men and to evaluate whether the dietary patterns were associated with bone mineral density change (%ΔBMD) at the total hip and femoral neck over time...
February 15, 2018: Osteoporosis International
https://www.readbyqxmd.com/read/29450484/neurological-manifestations-among-us-government-personnel-reporting-directional-audible-and-sensory-phenomena-in-havana-cuba
#17
Randel L Swanson, Stephen Hampton, Judith Green-McKenzie, Ramon Diaz-Arrastia, M Sean Grady, Ragini Verma, Rosette Biester, Diana Duda, Ronald L Wolf, Douglas H Smith
Importance: From late 2016 through August 2017, US government personnel serving on diplomatic assignment in Havana, Cuba, reported neurological symptoms associated with exposure to auditory and sensory phenomena. Objective: To describe the neurological manifestations that followed exposure to an unknown energy source associated with auditory and sensory phenomena. Design, Setting, and Participants: Preliminary results from a retrospective case series of US government personnel in Havana, Cuba...
February 15, 2018: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29449113/characterization-of-the-non-metal-fraction-of-the-processed-waste-printed-circuit-boards
#18
Amit Kumar, Maria E Holuszko, Travis Janke
Electronic waste is one the fastest growing waste streams in the world and waste printed circuit boards (PCB) are the most valuable part of this stream due to the presence of gold, silver, copper, and palladium. The metal present in PCBs is mostly recovered for the market value whereas the nonmetal fractions are often ignored. This research explored the characteristics of the non-metal fraction (NMF) obtained after the processing of milled waste PCBs with a focus on responsible end-of-life solutions, in the form of non-hazardous landfilling or incineration...
February 12, 2018: Waste Management
https://www.readbyqxmd.com/read/29448667/temperature-dependence-of-oxide-semiconductor-and-channel-effect-of-thin-film-transistor
#19
Teresa Oh
ZTO was prepared on SiOC/ITO glass and the electrical characteristics were analyzed in accordance with the annealing temperature to research the temperature dependence and an amorphous structure. SiOC annealed at 150 °C as a gate insulator became an amorphous structure. The ZTO annealed at 150 °C had the capacitance without any variation. However, the capacitance of ZTO on SiOC annealed at 150 °C was increased due to the reduction of energy loss. ZTO/SiOC transistor was observed the ambipolar transfer characteristics with high stability and mobility in accordance with the decrement of drain voltages as a result of tunneling effect...
March 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29448657/numerical-analysis-of-the-temperature-impact-on-performance-of-gan-based-460-nm-light-emitting-diode
#20
Wael Z Tawfik, June Key Lee
The influence of temperature on the characteristics of a GaN-based 460-nm light-emitting diode (LED) prepared on sapphire substrate was simulated using the SiLENSe and SpeCLED software programs. High temperatures impose negative effects on the performance of GaN-based LEDs. As the temperature increases, electrons acquire higher thermal energies, and therefore LEDs may suffer more from high-current loss mechanisms, which in turn causes a reduction in the radiative recombination rate in the active region. The internal quantum efficiency was reduced by about 24% at a current density of 35 A/cm2, and the electroluminescence spectral peak wavelength was redshifted...
March 1, 2018: Journal of Nanoscience and Nanotechnology
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