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https://www.readbyqxmd.com/read/29662836/association-between-loss-of-skeletal-muscle-mass-and-mortality-and-tumor-recurrence-in-hepatocellular-carcinoma-a-systematic-review-and-meta-analysis
#1
REVIEW
Ke-Vin Chang, Jin-De Chen, Wei-Ting Wu, Kuo-Chin Huang, Chia-Tzu Hsu, Der-Sheng Han
Background: Hepatocellular carcinoma (HCC) has multiple prognostic factors, and there is an increase in knowledge about the body composition and physical status of patients with HCC. The present meta-analysis aimed to explore whether loss of skeletal muscle mass is associated with mortality and tumor recurrence in patients with HCC. Method: A systematic search was conducted for published literature using PubMed, Embase, and Scopus. We included cohort or case-control studies investigating patients with HCC...
March 2018: Liver Cancer
https://www.readbyqxmd.com/read/29661941/mental-health-of-transgender-and-gender-nonconforming-youth-compared-with-their-peers
#2
Tracy A Becerra-Culqui, Yuan Liu, Rebecca Nash, Lee Cromwell, W Dana Flanders, Darios Getahun, Shawn V Giammattei, Enid M Hunkeler, Timothy L Lash, Andrea Millman, Virginia P Quinn, Brandi Robinson, Douglas Roblin, David E Sandberg, Michael J Silverberg, Vin Tangpricha, Michael Goodman
BACKGROUND: Understanding the magnitude of mental health problems, particularly life-threatening ones, experienced by transgender and/or gender nonconforming (TGNC) youth can lead to improved management of these conditions. METHODS: Electronic medical records were used to identify a cohort of 588 transfeminine and 745 transmasculine children (3-9 years old) and adolescents (10-17 years old) enrolled in integrated health care systems in California and Georgia. Ten male and 10 female referent cisgender enrollees were matched to each TGNC individual on year of birth, race and/or ethnicity, study site, and membership year of the index date (first evidence of gender nonconforming status)...
April 16, 2018: Pediatrics
https://www.readbyqxmd.com/read/29618781/recycling-waste-soot-from-merchant-ships-to-produce-anode-materials-for-rechargeable-lithium-ion-batteries
#3
Won-Ju Lee, Han Vin Kim, Jae-Hyuk Choi, Gasidit Panomsuwan, Young-Chan Lee, Beom-Seok Rho, Jun Kang
In this study, the waste soot generated by ships was recycled to produce an active material for use in lithium-ion batteries (LIBs). Soot collected from a ship was graphitized by a heat treatment process and used as an anode active material. It was confirmed that the graphitized soot was converted into a highly crystalline graphite, and was found to form carbon nano-onions with an average diameter of 70 nm. The graphitized soot showed a high discharge capacity and an excellent cycle life, with a reversible capacity of 260 mAhg-1 even after 150 cycles at a rate of 1 C...
April 4, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29618089/a-rare-ultrasonographic-finding-in-pudendal-neuralgia-posteriorly-prolapsed-cervix
#4
Ke-Vin Chang, Wei-Ting Wu, Levent Özçakar, Carlo Martinoli
No abstract text is available yet for this article.
March 30, 2018: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29607111/call-for-screening-for-primary-aldosteronism-an-underdiagnosed-and-treatable-disease
#5
EDITORIAL
Leay Kiaw Er, Vin-Cent Wu
No abstract text is available yet for this article.
February 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29604401/limb-muscle-quality-and-quantity-in-elderly-adults-with-dynapenia-but-not-sarcopenia-an-ultrasound-imaging-study
#6
Ke-Vin Chang, Wei-Ting Wu, Kuo-Chin Huang, Wei Han Jan, Der-Sheng Han
BACKGROUND: Dynapenia is prevalent in people with reduced skeletal muscle mass, i.e. sarcopenia, but a certain population develops muscle strength loss despite having normal skeletal muscle volume. To date, studies investigating muscle quality and quantity in groups with dynapenia but not sarcopenia are limited. METHODS: Echogenicity and thickness of the biceps brachii, triceps brachii, rectus femoris, and medial gastrocnemius muscles were measured using high-resolution ultrasonography in 140 community-dwelling elderly adults...
March 28, 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29603681/a-comparative-cfd-study-of-four-inferior-vena-cava-filters
#7
Josep M López, Gerard Fortuny, Dolors Puigjaner, Joan Herrero, Francesc Marimon
Computational fluid dynamics was used to simulate the flow of blood within an inferior vena cava (IVC) geometry model that was reconstructed from computed tomography images obtained from a real patient. The main novelty of the present work is that we simulated the implantation of four different filter models in this realistic IVC geometry. We considered different blood flow rates in the range between Vin =20 and Vin =80cm3 /s and all simulations were performed with both the Newtonian and a non-Newtonian model for the blood viscosity...
March 30, 2018: International Journal for Numerical Methods in Biomedical Engineering
https://www.readbyqxmd.com/read/29603619/a-new-strategy-for-maximizing-the-storage-capacity-of-lithium-in-carbon-materials
#8
Jun Kang, Han-Vin Kim, Seen-Ae Chae, Kwang-Ho Kim
A novel strategy for maximizing the lithium storage capacity of carbon materials is reported. To redesign the interior structure, a large amount of Li, 4 wt%, is doped into the carbon during its synthesis. The Li-doped carbon is subsequently annealed, during which the diffusion of Li induces a disordered structure, thereby generating many nanocavities. The diffused Li atoms aggregate into a superdense state within the carbon structure; when the Li agglomerates escape from the carbon during the delithiation process, new void spaces are created at their location...
March 30, 2018: Small
https://www.readbyqxmd.com/read/29599812/study-of-pharmacodynamic-and-pharmacokinetic-interaction-of-bojungikki-tang-with-aspirin-in-healthy-subjects-and-ischemic-stroke-patients
#9
Jung-Hwa Yoo, Sung-Vin Yim, Byung-Cheol Lee
Background: Bojungikki-tang (BJIKT) is a widely used traditional herbal formula in China, Japan, and Korea. There have been reports that several herbs among BJIKT have interactions with antiplatelet drugs, such as aspirin. This study aimed to assess whether BJIKT interacts with aspirin in terms of pharmacokinetics (PK) and pharmacodynamics (PD) in healthy subjects and ischemic stroke patients. Methods: The phase I interaction trial was a randomized, open-label, crossover study of 10 healthy male subjects, and the phase III interaction trial was a randomized, placebo-controlled, parallel study of 43 ischemic stroke patients...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29578896/herniation-of-hoffa-s-fat-pad-through-the-lateral-retinaculum-usefulness-of-dynamic-ultrasonography-to-diagnose-a-lateral-knee-mass
#10
Kamal Mezian, Ke-Vin Chang, David Zámečník, Hassan Mezian, Levent Özçakar
No abstract text is available yet for this article.
March 24, 2018: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/29535025/intergenerational-response-to-the-endocrine-disruptor-vinclozolin-is-influenced-by-maternal-genotype-and-crossing-scheme
#11
Edward W Pietryk, Kiristin Clement, Marwa Elnagheeb, Ryan Kuster, Kayla Kilpatrick, Michael I Love, Folami Y Ideraabdullah
In utero exposure to vinclozolin (VIN), an antiandrogenic fungicide, is linked to multigenerational phenotypic and epigenetic effects. Mechanisms remain unclear. We assessed the role of antiandrogenic activity and DNA sequence context by comparing effects of VIN vs. M2 (metabolite with greater antiandrogenic activity) and wild-type C57BL/6 (B6) mice vs. mice carrying mutations at the previously reported VIN-responsive H19/Igf2 locus. First generation offspring from VIN-treated 8nrCG mutant dams exhibited increased body weight and decreased sperm ICR methylation...
March 10, 2018: Reproductive Toxicology
https://www.readbyqxmd.com/read/29532733/has-development-assistance-for-health-facilitated-the-rise-of-more-peaceful-societies-in-sub-saharan-africa
#12
Vin Gupta, Alexandre Mason-Sharma, Zoe M Lyon, Endel John Orav, Ashish K Jha, Vanessa B Kerry
Growing evidence suggests that health aid can serve humanitarian and diplomatic ends. This study utilised the Fragile States Index (FSI) for the 47 nations of the World Health Organizations' Africa region for the years 2005-2014 and data on health and non-health development aid spending from the United States (US) for those same years. Absolute amounts of health and non-health aid flows from the US were used as predictors of state fragility. We used time-lagged, fixed-effects multivariable regression modelling with change in FSI as the outcome of interest...
March 13, 2018: Global Public Health
https://www.readbyqxmd.com/read/29529446/frequency-and-distribution-of-primary-site-among-gender-minority-cancer-patients-an-analysis-of-u-s-national-surveillance-data
#13
Rebecca Nash, Kevin C Ward, Ahmedin Jemal, David E Sandberg, Vin Tangpricha, Michael Goodman
BACKGROUND: Transgender people and persons with disorders of sex development (DSD) are two separate categories of gender minorities, each characterized by unique cancer risk factors. Although cancer registry data typically include only two categories of sex, registrars have the option of indicating that a patient is transgender or has a DSD. METHODS: Data for primary cancer cases in 46 states and the District of Columbia were obtained from the North American Association of Central Cancer Registries (NAACCR) database for the period 1995-2013...
March 9, 2018: Cancer Epidemiology
https://www.readbyqxmd.com/read/29523880/widespread-transduction-of-astrocytes-and-neurons-in-the-mouse-central-nervous-system-after-systemic-delivery-of-a-self-complementary-aav-php-b-vector
#14
Melvin Y Rincon, Filip de Vin, Sandra I Duqué, Shelly Fripont, Stephanie A Castaldo, Jessica Bouhuijzen-Wenger, Matthew G Holt
Until recently, adeno-associated virus 9 (AAV9) was considered the AAV serotype most effective in crossing the blood-brain barrier (BBB) and transducing cells of the central nervous system (CNS), following systemic injection. However, a newly engineered capsid, AAV-PHP.B, is reported to cross the BBB at even higher efficiency. We investigated how much we could boost CNS transgene expression by using AAV-PHP.B carrying a self-complementary (sc) genome. To allow comparison, 6 weeks old C57BL/6 mice received intravenous injections of scAAV2/9-GFP or scAAV2/PHP...
March 9, 2018: Gene Therapy
https://www.readbyqxmd.com/read/29519320/mechanism-of-action-of-cytotoxic-compounds-from-the-seeds-of-euphorbia-lathyris
#15
Yu-Ning Teng, Yingzi Wang, Pei-Ling Hsu, Guang Xin, Yu Zhang, Susan L Morris-Natschke, Masuo Goto, Kuo-Hsiung Lee
BACKGROUND: The seeds of Euphorbia lathyris are used in traditional Chinese medicines for the treatment of various medical conditions. E. lathyris contains many natural diterpenes with a lathyrane skeleton. PURPOSE AND STUDY DESIGN: Five lathyrane-type diterpenoids named Euphorbia factors L1 , L2 , L3 , L8 , and L9 (1-5), were investigated for cytotoxicity against A549, MDA-MB-231, KB, and MCF-7 cancer cell lines and the KB-VIN multidrug resistant (MDR) cancer cell line...
March 1, 2018: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/29507604/analysis-of-the-health-insurance-review-and-assessment-service-data-from-2011-to-2015
#16
Sang-Uk Lee, Minah Soh, Vin Ryu, Chul-Eung Kim, Subin Park, Sungwon Roh, In-Hwan Oh, Hye-Young Lee, SungKu Choi
Background: Schizophrenia is a recurrent, debilitating disease that is rarely curable. Rapid intervention after the first episode of schizophrenia has been shown to positively affect the prognosis. Unfortunately, basic data is scarce on first-episode schizophrenia in Korean patients making it difficult to create a comprehensive list of risk factors for relapse. This study aims to investigate the demographic characteristics and institutional factors of patients with first-episode schizophrenia in order to identify risk factors for relapse...
2018: International Journal of Mental Health Systems
https://www.readbyqxmd.com/read/29506889/targeted-treatment-of-primary-aldosteronism-the-consensus-of-taiwan-society-of-aldosteronism
#17
Kuo-How Huang, Chih-Chin Yu, Ya-Hui Hu, Chin-Chen Chang, Chieh-Kai Chan, Shih-Cheng Liao, Yao-Chou Tsai, Shih-Chieh Jeff Chueh, Vin-Cent Wu, Yen-Hung Lin
BACKGROUND/PURPOSE: Even with the increasing recognition of primary aldosteronism (PA) as a cause of refractory hypertension and an issue of public health, the consensus of its optimal surgical or medical treatment in Taiwan has not been reached. Our objective was to develop a clinical practice guideline that is feasible for real-world management of PA patients in Taiwan. METHODS: The Taiwan Society of Aldosteronism (TSA) Task Force recognized the above-mentioned issues and reached this Taiwan PA consensus at its inaugural meeting, in order to provide updated information of internationally acceptable standards, and also to incorporate our local disease characteristics and constraints into PA management...
March 2, 2018: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/29505145/high-dose-vitamin-d-3-administration-is-associated-with-increases-in-hemoglobin-concentrations-in-mechanically-ventilated-critically-ill-adults-a-pilot-double-blind-randomized-placebo-controlled-trial
#18
Ellen M Smith, Jennifer L Jones, Jenny E Han, Jessica A Alvarez, John H Sloan, Robert J Konrad, Susu M Zughaier, Greg S Martin, Thomas R Ziegler, Vin Tangpricha
BACKGROUND: Anemia and vitamin D deficiency are highly prevalent in critical illness, and vitamin D status has been associated with hemoglobin concentrations in epidemiologic studies. We examined the effect of high-dose vitamin D therapy on hemoglobin and hepcidin concentrations in critically ill adults. MATERIALS AND METHODS: Mechanically ventilated critically ill adults (N = 30) enrolled in a pilot double-blind, randomized, placebo-controlled trial of high-dose vitamin D3 (D3 ) were included in this analysis...
January 2018: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29498569/fifty-shades-of-gradients-does-the-pressure-gradient-in-venous-sinus-stenting-for-idiopathic-intracranial-hypertension-matter-a-systematic-review
#19
Cameron M McDougall, Vin Shen Ban, Jeffrey Beecher, Lee Pride, Babu G Welch
OBJECTIVE The role of venous sinus stenting (VSS) for idiopathic intracranial hypertension (IIH) is not well understood. The aim of this systematic review is to attempt to identify subsets of patients with IIH who will benefit from VSS based on the pressure gradients of their venous sinus stenosis. METHODS MEDLINE/PubMed was searched for studies reporting venous pressure gradients across the stenotic segment of the venous sinus, pre- and post-stent pressure gradients, and clinical outcomes after VSS. Findings are reported according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines...
March 2, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29481311/phytochemical-profile-toxicity-and-pharmacological-potential-of-peels-from-four-species-of-tropical-fruits
#20
Lilian Dolores Chel-Guerrero, Enrique Sauri-Duch, Mabel Clara Fragoso-Serrano, Laura Josefina Pérez-Flores, José Luis Gómez-Olivares, Noé Salinas-Arreortua, Edgar Del Carmen Sierra-Palacios, José Alberto Mendoza-Espinoza
Tropical fruit peels are generally discarded as waste, yet they contain bioactive substances that could have various uses; in addition, their pharmacological potential remains unexplored. This study aims to characterize the phytochemical profile, toxicity, and pharmacological potential of methanol extracts obtained from the peels of the following tropical fruit species: Annona squamosa L. (purple sugar apple), Annona reticulata L. (custard apple), Chrysophyllum cainito L. (green star apple), and Melicoccus bijugatus Jacq...
February 26, 2018: Journal of Medicinal Food
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