keyword
MENU ▼
Read by QxMD icon Read
search

VIN

keyword
https://www.readbyqxmd.com/read/29438546/high-intensity-ultrasound-treatment-for-vincristine-induced-neuropathic-pain
#1
Youngwon Youn, Abigail Hellman, Ian Walling, Lucy Gee, Jiang Qian, Clif Burdette, Lance Frith, Julie G Pilitsis
BACKGROUND: Vincristine is a commonly used chemotherapeutic agent that results in debilitating untreatable peripheral neuropathy. OBJECTIVE: To determine the effects of pulsed high-intensity focused ultrasound (HIFU) on sensory thresholds in a validated vincristine-induced neuropathy (VIN) rodent model. METHODS: VIN was induced and mechanical allodynia was confirmed by nociceptive testing. von Frey fibers and Randall-Sellito test were used as measures of innocuous and noxious mechanical thresholds, respectively, and the hot plate test for thermal thresholds...
February 9, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29434343/differential-expression-patterns-of-gata3-in-usual-and-differentiated-types-of-vulvar-intraepithelial-neoplasia-potential-diagnostic-implications
#2
Abha Goyal, Gloria Zhang, Bin Yang
The two main precursors of vulvar squamous cell carcinoma, usual and differentiated vulvar intraepithelial neoplasia (VIN), have distinctive etiology, pathogenesis, and natural history. Usual type VIN is often associated with high-risk HPV and differentiated VIN has de novo p53 genetic alterations that are unrelated to HPV infection. GATA-binding protein 3 (GATA3) is a tumor suppressor that shows increased expression in several types of human malignancies including breast and bladder carcinomas. Little is known regarding the expression of GATA3 in vulvar squamous neoplasms...
February 13, 2018: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
https://www.readbyqxmd.com/read/29429482/enteric-coronavirus-infection-in-adult-horses
#3
N Pusterla, R Vin, C M Leutenegger, L D Mittel, T J Divers
A new enteric virus of adult horses, equine coronavirus (ECoV), has recently been recognized. It is associated with fever, lethargy, anorexia, and less frequently, colic and diarrhea. This enteric virus is transmitted via the feco-oral route and horses become infected by ingesting fecally contaminated feed and water. Various outbreaks have been reported since 2010 from Japan, Europe and the USA. While the clinical signs are fairly non-specific, lymphopenia and neutropenia are often seen. Specific diagnosis is made by the detection of ECoV in feces by either quantitative real-time PCR, electron microscopy or antigen-capture ELISA...
January 2018: Veterinary Journal
https://www.readbyqxmd.com/read/29429013/demographic-presentation-and-treatment-factors-and-racial-disparities-in-ovarian-cancer-hospitalization-outcomes
#4
Tomi F Akinyemiju, Gurudatta Naik, Kemi Ogunsina, Daniel T Dibaba, Neomi Vin-Raviv
BACKGROUND: This study examines whether racial disparities in hospitalization outcomes persist between African-American and White women with ovarian cancer after matching on demographic, presentation, and treatment factors. METHODS: Using data from the Nationwide Inpatient Sample database, 5,164 African-American ovarian cancer patients were sequentially matched with White patients on demographic (e.g., age, income), presentation (e.g., stage, comorbidities), and treatment (e...
February 10, 2018: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/29422627/the-influence-of-the-peripheral-cortisol-fluctuation-on-the-success-rate-of-adrenal-venous-sampling
#5
Chin-Chen Chang, Bo-Ching Lee, Kao-Lang Liu, Yeun-Chung Chang, Vin-Cent Wu, Kuo-How Huang, Tung-Hsin Wu
In this retrospective study, we aimed to estimate the influence of fluctuating peripheral plasma cortisol concentration (PCC) on the success rate of non-stimulated adrenal venous sampling (AVS) and to demonstrate its fluctuating pattern. Overall, 107 consecutive patients with primary aldosteronism undergoing AVS between July 2015-January 2017 were included. The peripheral vein was sampled at 4 separate time points during the procedure: after femoral puncture, during left adrenal sampling, during right adrenal sampling, and before procedural ending...
February 8, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29421340/-violet-a-fluorescence-based-simulation-exercise-for-training-healthcare-workers-in-the-use-of-personal-protective-equipment
#6
Bozena Poller, Samantha Hall, Claire Bailey, Samantha Gregory, Richard Clark, Paul Roberts, Anne Tunbridge, Vin Poran, Brian Crook, Cariad Evans
BACKGROUND: Healthcare workers caring for patients with high consequence infectious diseases (HCID) require protection from pathogen exposure, for example by wearing personal protective equipment (PPE). Protection is acquired through the inherent safety of the PPE components, but also their safe and correct use, supported by adequate training and user familiarity. However, the evidence base for HCID PPE ensembles and any associated training is lacking, with subsequent variation between healthcare providers...
February 5, 2018: Journal of Hospital Infection
https://www.readbyqxmd.com/read/29416444/vinflunine-for-the-treatment-of-advanced-or-metastatic-transitional-cell-carcinoma-of-the-urothelial-tract-an-evidence-based-review-of-safety-efficacy-and-place-in-therapy
#7
REVIEW
Steven C Brousell, Joseph J Fantony, Megan G Van Noord, Michael R Harrison, Brant A Inman
Background: A systematic review and meta-analysis of the use of systemic vinflunine (VIN) in the treatment of urothelial carcinoma (UC) was performed to evaluate its efficacy based on current available clinical data. Methods: This review was prospectively registered at the International Prospective Register of Systematic Reviews, PROSPERO (registration CRD42016049294). Electronic databases including MEDLINE®, Embase®, Cochrane Central Register of Controlled Trials, and Web of Science were searched through December 2016...
2018: Core Evidence
https://www.readbyqxmd.com/read/29386545/hemojuvelin-predicts-acute-kidney-injury-and-poor-outcomes-following-cardiac-surgery
#8
Sheng-Wen Ko, Nai-Hsin Chi, Che-Hsiung Wu, Tao-Min Huang, Shih-Chieh Jeff Chueh, Chih-Hsien Wang, Jui-Hsiang Lin, Wei-Jie Wang, Jui-Tsung Ting, Huang-Ming Chang, Rory Connolly, Chien-Heng Lai, Li-Jung Tseng, Vin-Cent Wu, Tzong-Shinn Chu
Acute kidney injury (AKI) is detrimental after cardiac surgery. In this multicenter study, the novel biomarker hemojuvelin (HJV) was evaluated for AKI prediction following cardiac surgery. Urinary HJV, neutrophil gelatinase-associated lipocalin (NGAL), and urinary creatinine were measured in 151 patients after surgery. The outcomes of advanced AKI (KDIGO stages 2 and 3) and all causes of in-hospital mortality as the composite outcome were recorded. Areas under the receiver operator characteristic curves (AUC) and a multivariate generalized additive model (GAM) were applied to predict these outcomes of interest...
January 31, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29384989/reply
#9
Zheng-Wei Chen, Vin-Cent Wu, Yen-Hung Lin
No abstract text is available yet for this article.
March 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/29379204/a-broadband-achromatic-metalens-in-the-visible
#10
Shuming Wang, Pin Chieh Wu, Vin-Cent Su, Yi-Chieh Lai, Mu-Ku Chen, Hsin Yu Kuo, Bo Han Chen, Yu Han Chen, Tzu-Ting Huang, Jung-Hsi Wang, Ray-Ming Lin, Chieh-Hsiung Kuan, Tao Li, Zhenlin Wang, Shining Zhu, Din Ping Tsai
Metalenses consist of an array of optical nanoantennas on a surface capable of manipulating the properties of an incoming light wavefront. Various flat optical components, such as polarizers, optical imaging encoders, tunable phase modulators and a retroreflector, have been demonstrated using a metalens design. An open issue, especially problematic for colour imaging and display applications, is the correction of chromatic aberration, an intrinsic effect originating from the specific resonance and limited working bandwidth of each nanoantenna...
January 29, 2018: Nature Nanotechnology
https://www.readbyqxmd.com/read/29377603/effects-of-ojeok-san-on-the-pharmacokinetics-of-celecoxib-at-steady-state-in-healthy-subjects
#11
Sang-In Park, Ji-Young Park, Min-Ju Park, Sung-Vin Yim, Bo-Hyung Kim
Ojeok-san is a frequently used herbal medication for the management of osteoarthritic pain. We evaluated the effect of Ojeok-san on the pharmacokinetics of celecoxib at steady state in healthy subjects. An open-label, fixed-sequence, two-period, two-treatment cross-over study was conducted. In period I, the subjects received celecoxib capsule 200 mg once daily for 4 days. In period II, only Ojeok-san (14.47 g/pack, three times daily) was administered for 4 days, followed by co-administration with celecoxib for 4 days...
January 28, 2018: Basic & Clinical Pharmacology & Toxicology
https://www.readbyqxmd.com/read/29367185/effect-of-contract-compliance-rate-to-a-fourth-generation-telehealth-program-on-the-risk-of-hospitalization-in-patients-with-chronic-kidney-disease-retrospective-cohort-study
#12
Chi-Sheng Hung, Jenkuang Lee, Ying-Hsien Chen, Ching-Chang Huang, Vin-Cent Wu, Hui-Wen Wu, Pao-Yu Chuang, Yi-Lwun Ho
BACKGROUND: Chronic kidney disease (CKD) is prevalent in Taiwan and it is associated with high all-cause mortality. We have shown in a previous paper that a fourth-generation telehealth program is associated with lower all-cause mortality compared to usual care with a hazard ratio of 0.866 (95% CI 0.837-0.896). OBJECTIVE: This study aimed to evaluate the effect of renal function status on hospitalization among patients receiving this program and to evaluate the relationship between contract compliance rate to the program and risk of hospitalization in patients with CKD...
January 24, 2018: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29360942/il-6-trans-activation-contributes-to-aldosterone-induced-cardiac-fibrosis
#13
Chia-Hung Chou, Chi-Sheng Hung, Che-Wei Liao, Lin-Hung Wei, Ching-Way Chen, Chia-Tung Shun, Wen-Fen Wen, Cho-Hua Wan, Xue-Ming Wu, Yi-Yao Chang, Vin-Cent Wu, Kwan-Dun Wu, Yen-Hung Lin
Aims: An excess of aldosterone results in cardiac remodeling and fibrosis. Interleukin-6 (IL-6) is a key mediator in the fibrotic process, however the effect of aldosterone on the expression of IL-6 remains unclear. We investigated whether aldosterone induces the expression of IL-6 and thereby contributes to the fibrotic process. Methods and Results: In this clinical study, we prospectively enrolled 25 patients with primary aldosteronism (PA) and 26 patients with essential hypertension (EH)...
January 19, 2018: Cardiovascular Research
https://www.readbyqxmd.com/read/29348869/role-of-the-n-terminal-lid-in-regulating-the-interaction-of-phosphorylated-mdmx-with-p53
#14
Jane Vin Chan, Dawn Xin Ping Koh, Yun Liu, Thomas L Joseph, David P Lane, Chandra S Verma, Yaw Sing Tan
Murine double minute 4 protein (MDMX) is crucial for the regulation of the tumor suppressor protein p53. Phosphorylation of the N-terminal domain of MDMX is thought to affect its binding with the transactivation domain of p53, thus playing a role in p53 regulation. In this study, the effects of MDMX phosphorylation on the binding of p53 were investigated using molecular dynamics simulations. It is shown that in addition to the previously proposed mechanism in which phosphorylated Y99 of MDMX inhibits p53 binding through steric clash with P27 of p53, the N-terminal lid of MDMX also appears to play an important role in regulating the phosphorylation-dependent interactions between MDMX and p53...
December 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/29336101/recurrence-of-vulval-intraepithelial-neoplasia-following-treatment-with-cidofovir-or-imiquimod-results-from-a-multi-centre-randomised-phase-ii-trial-rt3vin
#15
Christopher N Hurt, Sadie E F Jones, Tracie-Ann Madden, Alison Fiander, Andrew J Nordin, Raj Naik, Ned Powell, Margherita Carucci, Amanda Tristram
OBJECTIVE: To compare the recurrence rates after complete response to topical treatment with either cidofovir or imiquimod for vulval intraepithelial neoplasia (VIN) 3. DESIGN: A prospective, open, randomised multicentre trial. SETTING: 32 general hospitals located in Wales and England. POPULATION OR SAMPLE: 180 patients were randomised consecutively between Oct 21, 2009, and Jan 11, 2013, 89 to cidofoovir (of whom 41 completely responded to treatment) and 91 to imiquimod (of whom 42 completely responded to treatment)...
January 16, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29329546/whole-genome-sequencing-of-genotype-vi-newcastle-disease-viruses-from-formalin-fixed-paraffin-embedded-tissues-from-wild-pigeons-reveals-continuous-evolution-and-previously-unrecognized-genetic-diversity-in-the-u-s
#16
Ying He, Tonya L Taylor, Kiril M Dimitrov, Salman L Butt, James B Stanton, Iryna V Goraichuk, Heather Fenton, Rebecca Poulson, Jian Zhang, Corrie C Brown, Hon S Ip, Marcos Isidoro-Ayza, Claudio L Afonso
BACKGROUND: Newcastle disease viruses (NDV) are highly contagious and cause disease in both wild birds and poultry. A pigeon-adapted variant of genotype VI NDV, often termed pigeon paramyxovirus 1, is commonly isolated from columbids in the United States and worldwide. Complete genomic characterization of these genotype VI viruses circulating in wild columbids in the United States is limited, and due to the genetic variability of the virus, failure of rapid diagnostic detection has been reported...
January 12, 2018: Virology Journal
https://www.readbyqxmd.com/read/29325871/use-of-uv-fluorescence-based-simulation-in-evaluation-of-personal-protective-equipment-worn-for-first-assessment-and-care-of-a-patient-with-suspected-high-consequence-infectious-disease
#17
Samantha Hall, Bozena Poller, Claire Bailey, Samantha Gregory, Richard Clark, Paul Roberts, Anne Tunbridge, Vin Poran, Cariad Evans, Brian Crook
BACKGROUND: Variations currently exist across the UK in the choice of personal protective equipment (PPE) used by healthcare workers when caring for patients with suspected high consequence infectious diseases (HCIDs). AIM: To test the protection afforded to healthcare workers by current PPE ensembles during assessment of a suspected HCID case and to provide an evidence base to justify proposal of a unified PPE ensemble for healthcare workers across the UK. METHODS: One 'basic level' (enhanced precautions) PPE ensemble and five 'suspected case' PPE ensembles were evaluated in volunteer trials using 'Violet'; a UV-fluorescence-based simulation exercise to visualise exposure/contamination events...
January 8, 2018: Journal of Hospital Infection
https://www.readbyqxmd.com/read/29324910/deep-brain-nucleus-targeting-in-parkinson-s-disease-and-essential-tremor-by-image-guided-surgery-using-neuronavigation-system-with-tractography-and-volume-of-tissue-of-activated-assessment
#18
Amir Nikouei, Pooya Torkian, Tohid Emami Meybodi, Arash Javad Mousavi, Amir Saied Seddighi
OBJECTIVE: Deep Brain Stimulation (DBS) is an effective surgical approach for treatment of Parkinson's disease (PD), dystonia and essential tremor (ET). Traditionally, DBS is performed using frame-based stereotactic technique. Recently, image guided surgery (IGS) using neuronavigation has gained popularity in neurosurgical procedures. We aim to investigate whether DBS using neuronavigation is capable of improving patient's outcome and minimize its complications. SUBJECT AND METHODS: From February 2011 to October 2016, 20 patients with PD and 6 patients with ET were enrolled in the study...
September 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/29324458/ultrasound-imaging-and-guided-injection-for-the-lateral-and-posterior-hip
#19
Ke-Vin Chang, Wei-Ting Wu, Henry L Lew, Levent Özçakar
Ultrasound has emerged as one of the most utilized tools to diagnose musculoskeletal disorders and to assist in interventions. Traditionally, sonographic examination of the hip joint has been challenging because most of the major structures are deeply situated, thus requiring the use of curvilinear transducer for better penetrance. The posterior lateral hip is a frequent area for musculoskeletal pain and nerve entrapments. Common disorders include greater trochanteric pain syndrome, gluteus medius tendinopathy, piriformis syndrome, pudendal neuralgia and proximal hamstring tendinopathy...
January 11, 2018: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/29320643/2017-american-association-of-clinical-endocrinologists-endocrine-society-update-on-transgender-medicine-case-discussions
#20
Vin Tangpricha, Sabine E Hannema, Michael S Irwig, Walter J Meyer, Joshua D Safer, Wylie C Hembree
OBJECTIVE: Increased numbers of transgender and gender-nonconforming people are presenting to physicians in the United States and abroad due to increased public recognition and acceptance and increased access to healthcare facilities. However, there are still gaps in medical knowledge among endocrinologists and other health care professionals. The purpose of these cases is to present several common clinical vignettes of transgender people presenting in an office setting that illustrate some of the key recommendations of the Endocrine Society's revised Endocrine Treatment of Gender Dysphoria/Gender Incongruent Persons guidelines, cosponsored by the American Association of Clinical Endocrinologists...
December 2017: Endocrine Practice
keyword
keyword
33685
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"