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https://www.readbyqxmd.com/read/28321026/left-ventricular-outflow-tract-migration-of-a-balloon-expandable-prosthesis-during-transcatheter-aortic-valve-implantation
#1
Daisuke Hachinohe, Ken Kobayashi, Azusa Furugen, Ryuji Koshima
Valve migration into the left ventricular outflow tract (LVOT) during transcatheter aortic valve implantation (TAVI) is a life-threatening complication. An 89-year-old female patient was admitted for TAVI due to severe symptomatic aortic stenosis. After deployment of a balloon-expandable prosthesis, the prosthesis had migrated into the LVOT. The prosthesis was reimpacted to the aortic annulus by a balloon-assisted recapture procedure. Immediately after recapturing the prosthesis with an oversized balloon, the patient's vital signs deteriorated due to acute aortic regurgitation (AR), and a prompt valve-in-valve (V-in-V) procedure allowed us to stabilize the patient's condition...
March 17, 2017: International Heart Journal
https://www.readbyqxmd.com/read/28285912/design-synthesis-and-potent-cytotoxic-activity-of-novel-7-n-substituted-sulfonyl-piperazinyl-methyl-camptothecin-derivatives
#2
Gao-Xiang Zhu, Pi-Le Cheng, Masuo Goto, Na Zhang, Susan L Morris-Natschke, Kan-Yen Hsieh, Guan-Zhou Yang, Qian-Ru Yang, Ying-Qian Liu, Hai-Le Chen, Xiao-Shuai Zhang, Kuo-Hsiung Lee
In an effort to discover potent camptothecin-derived antitumor agents, novel camptothecin analogues with sulfonylpiperazinyl motifs at position-7 were designed and synthesized. They were evaluated for in vitro cytotoxicity with the sulforhodamine-B (SRB) method in five types of human tumor cell lines, A-549, MDA-MB-231, KB, KB-VIN and MCF-7. With IC50 values in the low μM to nM level, most of the new analogues showed greater cytotoxicity activity than the reference compounds irinotecan and topotecan. Furthermore, compounds 12l (IC50, 1...
February 28, 2017: Bioorganic & Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/28264546/sonographic-guide-for-botulinum-toxin-injections-of-the-upper-limb-euro-musculus-usprm-spasticity-approach
#3
Murat Kara, Bayram Kaymak, Alper M Ulaşli, Fatih Tok, Gokhan T Öztürk, Ke-Vin Chang, Ming-Yen Hsiao, Chen-Yu Hung, Arzu Yağiz On, Levent Özçakar
The pertinent literature lacks overt technical data for optimal upper limb muscle botulinum toxin injections using ultrasound (US) imaging. Therefore, this guide is prepared for the commonly injected muscles of the upper limb and the shoulder girdle mainly in spasticity. It includes clinical information, anatomical description and explanation regarding the US imaging of several muscles. The figures have been organized to orient the readers on the innervation zones, injection sites, probe positionings and the US images simultaneously...
March 6, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28263111/survey-of-attitudes-toward-and-experiences-with-animal-abuse-encounters-in-a-convenience-sample-of-us-veterinarians
#4
Lori R Kogan, Regina M Schoenfeld-Tacher, Peter W Hellyer, Mark Rishniw, Rebecca A Ruch-Gallie
OBJECTIVE To survey practicing veterinarians regarding their perceptions of and experiences with cases of suspected or confirmed animal abuse and related state laws. DESIGN Cross-sectional study. POPULATION Members of the Veterinary Information Network (VIN; n = 34,144) who were in veterinary practice at the time of the survey. PROCEDURES A survey was designed and distributed online to all VIN members from January 26 to February 28, 2015. Responses were compiled, and binary logistic regression analysis was performed to identify factors that influenced decisions or perceptions regarding animal abuse encounters and related legislation...
March 15, 2017: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/28254655/real-life-dose-emission-characterization-using-copd-patient-inhalation-profiles-when-they-inhaled-using-a-fixed-dose-combination-fdc-of-the-medium-strength-symbicort-%C3%A2-turbuhaler-%C3%A2
#5
Golshan Bagherisadeghi, El Hassane Larhrib, Henry Chrystyn
The dose emitted from dry powder inhalers (DPI) is inhalation flow dependent and so varies with the peak inhalation flow (PIF) of a patient's inhalation maneuver (IM). Dose emission could also be affected by other IM parameters-the inhaled volume (Vin) and the initial acceleration rate of the IM (ACIM). We have adapted the compendial method for in-vitro DPI determinations so that inhalation profiles replace the inhalation square profile generated by a vacuum pump. These real-life patient inhalation profiles were measured when 18 COPD patients inhaled through an empty placebo Symbicort(®) Turbuhaler(®)...
February 28, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28246085/globally-inclusive-investments-in-health-benefits-at-home-and-abroad
#6
EDITORIAL
Vin Gupta, Vanessa B Kerry
No abstract text is available yet for this article.
February 28, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28245972/static-and-dynamic-shoulder-imaging-to-predict-initial-effectiveness-and-recurrence-after-ultrasound-guided-subacromial-corticosteroid-injections
#7
Ke-Vin Chang, Wei-Ting Wu, Der-Sheng Han, Levent Özçakar
OBJECTIVE: To explore factors contributing to initial effectiveness and recurrence after ultrasound (US)-guided subacromial corticosteroid injections by assessing clinical measurements as well as static and dynamic shoulder US images. DESIGN: Retrospective cohort study. SETTING: Rehabilitation outpatient clinic. PARTICIPANTS: Adults with shoulder pain referred for injection therapy. INTERVENTIONS: US-guided subacromial corticosteroid injection...
February 25, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28231579/vibration-induced-nystagmus-a-biomarker-for-vestibular-deficits-a-synopsis
#8
Karl-Friedrich Hamann
A review of more than 20 years of experience with vibratory stimulation in vestibular diseases is given. Vibrations in a frequency frame of 30-60 Hz are applied on the mastoid during 20 s. Eye movements are recorded by video-oculography to detect a vibration-induced nystagmus (VIN). A VIN occurs in cases of a side difference between the peripheral vestibular receptors beating to the side of better excitability. In patients with central lesions, a VIN does not appear generally, only exceptionally if the lesion is located laterally in the brain stem...
2017: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/28208992/an-uncommon-cause-of-posterior-leg-pain-ultrasound-image-of-plantaris-tendinopathy
#9
Chen-Yu Hung, Ke-Vin Chang
No abstract text is available yet for this article.
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28196182/what-surgeons-need-to-know-about-gender-confirmation-surgery-when-providing-care-for-transgender-individuals-a-review
#10
Jens U Berli, Gail Knudson, Lin Fraser, Vin Tangpricha, Randi Ettner, Frederic M Ettner, Joshua D Safer, Julie Graham, Stan Monstrey, Loren Schechter
Importance: In 2014, the US Department of Health and Human Services decided that its 1981 exclusion of transsexual surgical treatments from Medicare coverage was based on outdated, incomplete, and biased science and did not reflect current evidence or standards of care, and the exclusion was therefore lifted. As a direct result of this decision, surgeons nationwide are seeing an increase in consultations for surgical therapy to help transgender and gender-nonconforming individuals. Although some clinicians may have the technical training for such surgical procedures, in many cases, they may not have a full understanding of the complex and comprehensive care required to provide optimal health care for transgender individuals...
February 8, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/28178576/the-association-of-pre-treatment-hpv-subtypes-with-recurrence-of-vin
#11
Giorgio Bogani, Fabio Martinelli, Antonino Ditto, Mauro Signorelli, Francesca Taverna, Claudia Lombardo, Valentina Chiappa, Umberto Leone Roberti Maggiore, Dario Recalcati, Cono Scaffa, Stefania Perotto, Ilaria Sabatucci, Alice Indini, Domenica Lorusso, Francesco Raspagliesi
OBJECTIVE: To assess whether pre-treatment HPV types are associated with recurrence of high-grade vulvar intraepithelial neoplasia (VIN2+). STUDY DESIGN: Data of consecutive patients with pretreatment HPV DNA test undergoing treatment for VIN2+ were retrospectively collected. Risk factors promoting the risk of VIN2+ persistence and recurrence were analyzed using Kaplan-Meier and Cox hazard proportional models. RESULTS: 64 patients had pretreatment vulvar-vaginal HPV DNA test...
February 1, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28175512/303%C3%A2-aneurysmal-subarachnoid-hemorrhage-patients-risk-assessment-for-shunting-asah-paras-an-international-collaborative-study-and-initiation-of-a-consortium
#12
Hadie Adams, Vin Shen Ban, Ville Leinonen, Salah G Aoun, Jukka Huttunen, Taavi Saavalainen, Antti Lindgren, Juhana Frosen, Mikael Fraunberg, Timo Sakari Koivisto, Juha Antero Hernesniemi, Babu Guai Welch, Juha Jaaskelaine
No abstract text is available yet for this article.
August 1, 2016: Neurosurgery
https://www.readbyqxmd.com/read/28175486/359%C3%A2-delayed-treatment-of-ruptured-arteriovenous-malformations-is-it-ok-to-wait
#13
Jeffrey S Beecher, Awais Vance, Kristopher Allen Lyon, Vin Shen Ban, Cameron Michael McDougall, Louis A Whitworth, Jonathan A White, Duke S Samson, H Hunt Batjer, Babu Guai Welch
No abstract text is available yet for this article.
August 1, 2016: Neurosurgery
https://www.readbyqxmd.com/read/28175374/115%C3%A2-the-southwestern-aneurysm-scoring-index-prediction-of-outcomes-at-1-year-in-ruptured-aneurysms-treated-with-microsurgery
#14
Vin Shen Ban, Jeffrey S Beecher, Christopher S Eddleman, Salah G Aoun, Kristopher Allen Lyon, Tarek Youssef El Ahmadieh, Cameron Michael McDougall, Babu Guai Welch, Joan Reisch, H Hunt Batjer, Duke S Samson, Jonathan A White
No abstract text is available yet for this article.
August 1, 2016: Neurosurgery
https://www.readbyqxmd.com/read/28161530/effects-of-cholecalciferol-supplementation-on-serum-and-urinary-vitamin-d-metabolites-and-binding-protein-in-hiv-infected-youth
#15
Allison Ross Eckard, Myrtle Thierry-Palmer, Natalia Silvestrov, Julia C Rosebush, Mary Ann O'Riordan, Julie E Daniels, Monika Uribe-Leitz, Danielle Labbato, Joshua H Ruff, Ravinder J Singh, Vin Tangpricha, Grace A McComsey
Vitamin D insufficiency is widespread in HIV-infected patients. HIV and/or antiretroviral therapy (ART), particularly efavirenz (EFV), may interfere with vitamin D metabolism. However, few data from randomized, controlled trials exist. Here, we investigate changes in vitamin D metabolites and binding protein (VDBP) after 6 months of supplementation in a randomized, active-control, double-blind trial investigating 2 different monthly cholecalciferol (vitamin D3) doses [60,000 (medium) or 120,000 (high) IU/month] vs...
February 1, 2017: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/28134785/a-comparative-study-of-the-phenolic-and-technological-maturities-of-red-grapes-grown-in-lebanon
#16
Hiba N Rajha, Nada El Darra, Sally El Kantar, Zeina Hobaika, Nicolas Louka, Richard G Maroun
Grape harvest date is determined according to the technological and phenolic maturities. These parameters were calculated for different red grape (Vitis vinifera L.) varieties (Cabernet Sauvignon, Merlot, Syrah, Cabernet Franc) over four years (2008, 2009, 2010, and 2011) (642 samples). Titratable acidity and sugar content of the grapes were used to determine the technological maturity, whereas Glories (1 and 2) and ITV (Institut Technique de la Vigne et du Vin) methods were used to monitor their phenolic maturity...
January 26, 2017: Antioxidants (Basel, Switzerland)
https://www.readbyqxmd.com/read/28130717/impact-of-dietary-intake-on-bone-turnover-in-patients-with-phenylalanine-hydroxylase-deficiency
#17
Kathryn E Coakley, Eric I Felner, Vin Tangpricha, Peter W F Wilson, Rani H Singh
Phenylalanine hydroxylase (PAH) deficiency is a genetic disorder characterized by deficiency of the PAH enzyme. Patients follow a phenylalanine-restricted diet low in intact protein, and must consume synthetic medical food (MF) to supply phenylalanine-free protein. We assessed relationships between dietary intake and nutrient source (food or MF) on bone mineral density (BMD) and bone turnover markers (BTM) in PAH deficiency. Blood from 44 fasted females 11-52 years of age was analyzed for plasma phenylalanine, serum BTM [CTx (resorption), P1NP (formation)], vitamin D, and parathyroid hormone (PTH)...
January 28, 2017: JIMD Reports
https://www.readbyqxmd.com/read/28118273/ultrasound-guided-c7-cervical-medial-branch-block-using-the-in-plane-approach
#18
Ke-Vin Chang, Wei-Ting Wu, Levent Özçakar
No abstract text is available yet for this article.
January 23, 2017: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/28115867/sonographic-tracking-of-trunk-nerves-essential-for-ultrasound-guided-pain-management-and-research
#19
Ke-Vin Chang, Chih-Peng Lin, Chia-Shiang Lin, Wei-Ting Wu, Manoj K Karmakar, Levent Özçakar
Delineation of architecture of peripheral nerves can be successfully achieved by high-resolution ultrasound (US), which is essential for US-guided pain management. There are numerous musculoskeletal pain syndromes involving the trunk nerves necessitating US for evaluation and guided interventions. The most common peripheral nerve disorders at the trunk region include thoracic outlet syndrome (brachial plexus), scapular winging (long thoracic nerve), interscapular pain (dorsal scapular nerve), and lumbar facet joint syndrome (medial branches of spinal nerves)...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28111615/the-effects-of-first-line-anti-tuberculosis-drugs-on-the-actions-of-vitamin-d-in-human-macrophages
#20
Supavit Chesdachai, Susu M Zughaier, Li Hao, Russell R Kempker, Henry M Blumberg, Thomas R Ziegler, Vin Tangpricha
Tuberculosis (TB) is a major global health problem. Patients with TB have a high rate of vitamin D deficiency, both at diagnosis and during the course of treatment with anti-tuberculosis drugs. Although data on the efficacy of vitamin D supplementation on Mycobacterium tuberculosis (Mtb) clearance is uncertain from randomized controlled trials (RCTs), vitamin D enhances the expression of the anti-microbial peptide human cathelicidin (hCAP18) in cultured macrophages in vitro. One possible explanation for the mixed (primarily negative) results of RCTs examining vitamin D treatment in TB infection is that anti-TB drugs given to enrolled subjects may impact actions of vitamin D to enhance cathelicidin in macrophages...
December 2016: Journal of Clinical & Translational Endocrinology
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