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https://www.readbyqxmd.com/read/28534980/a-proteomic-analysis-identifies-candidate-early-biomarkers-to-predict-ovarian-hyperstimulation-syndrome-in-polycystic-ovarian-syndrome-patients
#1
Lan Wu, Yazhou Sun, Jun Wan, Ting Luan, Qing Cheng, Yong Tan
Ovarian hyperstimulation syndrome (OHSS) is a potentially life‑threatening, iatrogenic complication that occurs during assisted reproduction. Polycystic ovarian syndrome (PCOS) significantly increases the risk of OHSS during controlled ovarian stimulation. Therefore, a more effective early prediction technique is required in PCOS patients. Quantitative proteomic analysis of serum proteins indicates the potential diagnostic value for disease. In the present study, the authors revealed the differentially expressed proteins in OHSS patients with PCOS as new diagnostic biomarkers...
May 18, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28534597/metabolomics-for-improving-pregnancy-outcomes-in-women-undergoing-assisted-reproductive-technologies
#2
REVIEW
Charalampos S Siristatidis, Eleni Sertedaki, Dennis Vaidakis
BACKGROUND: In order to overcome the low effectiveness of assisted reproductive technologies (ART) and the high incidence of multiple births, metabolomics is proposed as a non-invasive method to assess oocyte quality, embryo viability, and endometrial receptivity, and facilitate a targeted subfertility treatment. OBJECTIVES: To evaluate the effectiveness and safety of metabolomic assessment of oocyte quality, embryo viability, and endometrial receptivity for improving live birth or ongoing pregnancy rates in women undergoing ART, compared to conventional methods of assessment...
May 23, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28531098/increase-in-weight-in-low-birth-weight-and-very-low-birth-weight-infants-fed-fortified-breast-milk-versus-formula-milk-a-retrospective-cohort-study
#3
Kris Yuet Wan Lok, Pui Hing Chau, Heidi Sze Lok Fan, Kam Ming Chan, Bill H Chan, Genevieve P C Fung, Marie Tarrant
There has been a dramatic rise in preterm births in developed countries owing to changes in clinical practices and greater use of assisted reproductive techniques. However, few studies have examined the growth and outcomes of preterm infants according to the type of feeding (with fortified breast milk or formula). The purpose of this study was to examine the effect of breast milk feedings and formula on the growth and short-term outcomes of preterm infants in Hong Kong. In a single-center retrospective cohort study, we included 642 preterm infants at gestational age <37 weeks with birth weights <2200 g...
May 20, 2017: Nutrients
https://www.readbyqxmd.com/read/28525345/in-vitro-production-of-sudanese-camel-camelus-dromedarius-embryos-from-epididymal-spermatozoa-and-follicular-oocytes-of-slaughtered-animals
#4
A E Abdelkhalek, Sh A Gabr, W A Khalil, Sh M Shamiah, L Pan, G Qin, M H Farouk
Application of assisted reproductive technology in camelidea, such as artificial insemination (AI) and embryo transfer, has been slow in comparison to that for other livestock species. In Egypt, there are few attempts to establish in vitro maturation (IVM) and fertilization (IVF) techniques in dromedary camel. The present study was carried out to produce Sudanese camel embryos using in vitro matured oocytes and epididymal spermatozoa. Dromedary camel ovaries were collected from abattoirs and then, the oocytes were aspirated from all the visible follicles on the ovarian surface (~2-8 mm in a diameter)...
March 28, 2017: Polish Journal of Veterinary Sciences
https://www.readbyqxmd.com/read/28520723/follicular-size-predicts-success-in-artificial-insemination-with-frozen-thawed-sperm-in-donkeys
#5
Joseph Saragusty, Alemayehu Lemma, Thomas Bernd Hildebrandt, Frank Göritz
In asses, semen collection, cryopreservation, and artificial insemination (AI) with frozen-thawed semen have been scarcely described and success rate, particularly following AI, is reportedly low. In the absence of reliable protocols, assisted reproductive technologies cannot support the conservation efforts aimed at endangered wild ass species and domestic donkey breeds. Two experiments were conducted in this study. In experiment 1 we evaluated freezing Abyssinian donkey (N = 5, 4 ejaculates each) spermatozoa using three freezing extenders (Berliner Cryomedium + glycerol, BC+G; BotuCrio, BOTU; INRAFreeze, INRA) and two cryopreservation techniques (liquid nitrogen vapour, LNV; directional freezing, DF)...
2017: PloS One
https://www.readbyqxmd.com/read/28514884/the-association-of-placenta-previa-and-assisted-reproductive-techniques-a-meta-analysis
#6
Manoochehr Karami, Ensiyeh Jenabi, Bita Fereidooni
BACKGROUND: Several epidemiological studies have determined that assisted reproductive techniques (ART) can increase the risk of placenta previa. To date, only a meta-analysis has been performed for assessing the relationship between placenta previa and ART. This meta-analysis was conducted to estimate the association between placenta previa and ART in singleton and twin pregnancies. METHODS: A literature search was performed in major databases PubMed, Web of Science, and Scopus from the earliest possible year to April 2017...
May 17, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28506951/pharmacokinetic-pharmacodynamic-and-clinical-aspects-of-ovulation-induction-agents-a-review-of-the-literature
#7
Serkan Kahyaoğlu, Bülent Yılmaz, Ahmet Zeki Işık
Controlled ovarian hyperstimulation is a key step for successful outcomes of assisted reproductive technique cycle outcomes. Many medications are available, which are commonly useed solely or in combination to achieve multiple follicular development. Pharmacokinetic, pharmacodynamic, and clinical information of ovulation induction drugs deserve to be elucidated for every individual patient before commencing infertility treatment. New concepts and new treatment protocols are introduced as ovulation physiology is understood by infertility specialists...
March 15, 2017: Journal of the Turkish German Gynecological Association
https://www.readbyqxmd.com/read/28506471/genetics-of-gonadotropins-and-their-receptors-as-markers-of-ovarian-reserve-and-response-in-controlled-ovarian-stimulation
#8
REVIEW
Laura Riccetti, Francesco De Pascali, Lisa Gilioli, Daniele Santi, Giulia Brigante, Manuela Simoni, Livio Casarini
Several controlled ovarian stimulation (COS) protocols have been developed to increase the yield of mature oocytes retrieved in assisted reproductive techniques (ARTs). The ovarian reserve (OR) influences the COS response, and it represents the main parameter that helps clinicians in refining clinical treatments in the perspective of a "personalized" ART. This approach is even more needed in particular conditions such as poor OR or polycystic ovary syndrome. Follicle-stimulating hormone, luteinizing hormone, and human chorionic gonadotropin are currently used in COS at different combinations and with different efficacies, even if the best approach definition is controversial...
April 17, 2017: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/28501368/contribution-of-immunology-to-implantation-failure-of-euploid-embryos
#9
REVIEW
Jason M Franasiak, Richard T Scott
Outcomes in assisted reproduction have seen marked improvement. With increased ability in the embryology laboratory to use extended embryo culture which in turn enables other selective techniques, such as trophectoderm biopsy and comprehensive chromosome screening, the chance of success per embryo transfer is increased. However, even the selection of a euploid blastocyst, which selects out many embryonic factors, does not yield successful implantation and ultimately delivery in all cases. Among the factors that affect implantation failure of apparently reproductively competent embryos, the immune system has been perhaps both the most plausible and the most debated...
May 10, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28501364/immune-modulation-treatments-where-is%C3%A2-the-evidence
#10
REVIEW
Malene Meisner Hviid, Nick Macklon
While advances in assisted reproductive techniques have been substantial, failure of the apparently viable embryo to implant remains a source of distress and frustration to patients and specialists alike. The unique maternal immunological response to the embryo and the notion that defects in early placentation underlie the great complications of pregnancy have focused attention on the therapeutic potential of peri-implantation immunomodulation. On the face of it, the rationale for this approach is very attractive...
May 10, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28497913/role-of-antioxidants-in-assisted-reproductive-techniques
#11
REVIEW
Ashok Agarwal, Ahmad Majzoub
Oxidative stress (OS) has been recognized as a significant cause of suboptimal assisted reproductive outcome. Many of the sperm preparation and manipulation procedures that are necessary in the in vitro environment can result in excessive production of reactive oxygen species (ROS) thereby exposing the gametes and growing embryos to significant oxidative damage. Antioxidants have long been utilized in the management of male subfertility as they can counterbalance the elevated levels of ROS inducing a high state of OS...
April 30, 2017: World Journal of Men's Health
https://www.readbyqxmd.com/read/28483506/laparoscopic-repair-of-a-symptomatic-post-cesarean%C3%A2-section-isthmocele-a-video-case-report
#12
Giorgio Aimi, Laura Buggio, Nicola Berlanda, Paolo Vercellini
OBJECTIVE: To describe our technique for laparoscopic management of post-cesarean section isthmocele. DESIGN: Surgical video article. Local Institutional Review Board approval for the video reproduction has been obtained. SETTING: University hospital. PATIENT(S): A 36-year-old patient with a history of two previous cesarean deliveries. She complained of persistent postmenstrual spotting and chronic pelvic pain. At transvaginal ultrasound examination, a cesarean scar defect of 20...
May 5, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28476487/a-randomized-controlled-trial-comparing-the-efficacy-and-safety-of-two-hmg-preparations-gaining-their-lh-bioactivity-from-different-hcg-sources
#13
Gillian Lockwood, Barbara Cometti, Jeanette Bogstad, Karin Erb, Christian De Geyter, Janos Urbancsek, Silvia Trevisan, Khaled Pocate-Cheriet, Dominique de Ziegler
In this prospective, controlled, randomized, multicentre, non-inferiority study, efficacy and safety of two HMG preparations (Menopur(®)- Ferring and Meriofert®- IBSA Institut Biochimique SA) for ovarian stimulation were compared (270 women undergoing IVF aged between 18 and 39 years; BMI 30 kg/m(2) or less; less than three prior completed assisted reproduction technique cycles). A standard long down-regulation with gonadotrophin-releasing hormone agonist protocol, with HCG triggering was used; primary end-point was total number of oocytes retrieved; attention was paid toovarian hyperstimulation syndrome (OHSS)...
April 20, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28470478/does-aps-impact-women-s-fertility
#14
REVIEW
Cecilia Beatrice Chighizola, Maria Gabriella Raimondo, Pier Luigi Meroni
PURPOSE OF REVIEW: This review focuses on the relationship between anti-phospholipid antibodies (aPL) and female infertility by addressing three key questions: (i) how can aPL induce women's infertility?; (ii) are aPL more prevalent among infertile than fertile women?; (iii) do aPL-positive women display reduced fertility? RECENT FINDINGS: According to experimental data, aPL impair female fertility interfering with endometrial decidualization thus with implantation...
June 2017: Current Rheumatology Reports
https://www.readbyqxmd.com/read/28467398/pathophysiology-and-management-of-urinary-tract-endometriosis
#15
REVIEW
Camran Nezhat, Rebecca Falik, Sara McKinney, Louise P King
Endometriosis predominantly affects the pelvic reproductive organs but can also affect the urinary tract. A number of theories for the pathogenesis of endometriosis have been suggested, but the exact mechanisms remain elusive. Endometriotic lesions can be found on both the ureter and bladder, and the optimal therapeutic approach depends on the extent, depth, and location of these lesions. Medical approaches, including hormonal therapies such as GnRH agonists and oral contraceptives, tend to be a temporary measure, but can be useful in a preoperative setting or if the patient is unsuitable for surgery, and are also useful as a postoperative treatment...
May 3, 2017: Nature Reviews. Urology
https://www.readbyqxmd.com/read/28455752/erratum-to-the-association-between-coenzyme-q10-concentrations-in-follicular-fluid-with-embryo-morphokinetics-and-pregnancy-rate-in-assisted-reproductive-techniques
#16
Süleyman Akarsu, Funda Gode, Ahmet Zeki Isik, Zeliha Günnur Dikmen, Mustafa Agah Tekindal
No abstract text is available yet for this article.
May 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28448801/the-placental-factor-in-spontaneous-preterm-birth-in-twin-vs-singleton-pregnancies
#17
Eran Weiner, Ann Dekalo, Ohad Feldstein, Elad Barber, Letizia Schreiber, Jacob Bar, Michal Kovo
OBJECTIVE: The association between infection and inflammatory response in singleton preterm birth (PTB) is well established, yet, less is known about PTB in twins. We aimed to compare the placental component and pregnancy outcome in pregnancies complicated with PTB of singletons vs. twin deliveries. We hypothesized that due to different underlying mechanisms, placental inflammatory lesions will be more prevalent in placentas derived from singleton pregnancies than twins. STUDY DESIGN: Labor characteristics, neonatal outcome and placental histopathology reports of spontaneous PTB at 24-33(6)/7 weeks, from 1/2008-12/2015, were reviewed...
April 22, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28447445/myomectomy-technique-and-current-indications
#18
Hajanirina Rakotomahenina, José Rajaonarison, Lufee Wong, Jean-Luc Brun
BACKGROUND: Uterine fibroids are the commonest benign tumor of the female genital tract. They affect a significant proportion of reproductive aged women and may cause excessive menstrual bleeding, pelvic pain or pressure, and adversely affect reproductive outcomes. However, many women remain asymptomatic. Fibroids are the first indication for hysterectomy, but myomectomy is the most suitable surgical option for women who desire preservation of their fertility potential. Only a selected group of women of childbearing age will benefit from a myomectomy, as the consequences of myomectomy on reproductive function have remained controversial...
April 26, 2017: Minerva Ginecologica
https://www.readbyqxmd.com/read/28447444/maternal-thyroid-function-in-women-undergoing-controlled-ovarian-hyperstimulation-during-in-vitro-fertilization-and-its-relation-to-reproductive-outcome
#19
Abdul K Abdul Karim, Muhammad Azrai Abu, Buvanes Chelliah, Zainul R Mohd Razi, Mohd H Omar, Hanita Othman, Zuraidah C Man
BACKGROUND: We conducted a study to evaluate the changes in thyroid function during Controlled Ovarian Hyperstimulation (COH) and its association with the outcome of assisted reproductive technique (ART). METHODS: This is a prospective cohort study done in University Hospital Fertility clinic for one year duration. A total of eighty eight euthyroid women who underwent COH as part of planned in vitro fertilization were invited to participate in this study. Serum thyroid function of each women will be monitored before stimulation (T1), day 10 -13 of cycle (T2), during oocyte retrieval (T3), one week following embryo transfer (T4) and at four weeks post embryo transfer(T5)...
April 26, 2017: Minerva Ginecologica
https://www.readbyqxmd.com/read/28443593/value-of-post-transfer-day-12-beta-human-chorionic-gonadotropin-levels-for-pregnancy-outcome-prediction-of-intracytoplasmic-sperm-injection-cycles
#20
İnci Kahyaoğlu, Berfu Demir, Sezin Ertürk Aksakal, İskender Kaplanoğlu, Leyla Mollamahmutoğlu
BACKGROUND: Several markers were studied previously in order to predict the pregnancy outcome of assisted reproductive techniques, however serum beta human chorionic gonadotropin (β-hCG) was found to be the most predictive marker. AIMS: The primary aim of this study was to evaluate the value of serum β-hCG levels in discriminating biochemical and clinical pregnancies 12 days after embryo transfer (ET) and to determine the factors predicting of ongoing pregnancy was established as the secondary aim...
April 13, 2017: Balkan Medical Journal
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