Anna Evans Phillips, Annette S Wilson, Phil J Greer, Alice Hinton, Stacey Culp, Pedram Paragomi, Ioannis Pothoulakis, Vijay Singh, Peter J Lee, Ila Lahooti, David C Whitcomb, Georgios I Papachristou
During acute pancreatitis (AP), free fatty acids (FFAs) are liberated from circulating triglycerides (TG) and injured adipocytes by pancreatic lipase. Circulating FFAs have been suspected as a source of systemic lipotoxicity in AP. However, assessment of FFAs is difficult and time-consuming, and little is known about relative levels of FFAs between patients with different severities of AP and controls. This study's aims were to assess early circulating levels of FFAs, (both saturated and unsaturated) in patients with AP vs...
September 1, 2023: American Journal of Physiology. Gastrointestinal and Liver Physiology