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https://www.readbyqxmd.com/read/28428174/klotho-an-anti-aging-molecule-attenuates-oxidant-induced-alveolar-epithelial-cell-mtdna-damage-and-apoptosis
#1
Seok-Jo Kim, Paul Cheresh, Mesut Eren, Renea P Jablonski, Anjana Yeldandi, Karen M Ridge, Gr Scott Budinger, Dong-Hyun Kim, Myles S Wolf, Douglas Vaughan, David W Kamp
Alveolar epithelial cell (AEC) apoptosis and inadequate repair resulting from 'exaggerated' lung aging and mitochondrial dysfunction are critical determinants promoting lung fibrosis. α-Klotho, which is an anti-aging molecule that is expressed predominantly in the kidney and secreted in the blood, can protect lung epithelial cells against hyperoxia-induced apoptosis. We reasoned that Klotho protects AEC exposed to oxidative stress in part by maintaining mitochondrial DNA (mtDNA) integrity and mitigating apoptosis...
April 20, 2017: American Journal of Physiology. Lung Cellular and Molecular Physiology
https://www.readbyqxmd.com/read/28422326/alveolar-ridge-dimensional-changes-following-ridge-preservation-procedure-with-novel-devices-part-3-histological-analysis-in-non-human-primate-model
#2
Yingying Su, Jianxia Tang, Seiko Min, Lijia Guo, Yitong Liu, Yilin Xie, Jimin Xiong, Songlin Wang, Mauricio G Araújo, Homayoun H Zadeh, Yi Liu
OBJECTIVES: This study sought to investigate the histological changes following tooth extraction, ridge preservation and augmentation, using novel devices designed to obturate the oral orifice of extraction sockets (SocketKAP™) and provide structural support for sockets with defective bony walls (SocketKAGE™) in a non-human primate model. MATERIAL AND METHODS: Six Macaca fascicularis were imaged by cone beam computed tomography to register their preoperative alveolar bone...
April 19, 2017: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/28402354/simultaneous-ridge-augmentation-and-accelerated-molar-uprighting-for-implant-site-development-two-case-reports-with-a-split-mouth-design
#3
Chin-Wei Wang, Michelle Yuching Chou, Rebecca Chen, Todd Rowe, Mohamed Masoud, David M Kim, Giuseppe Intini
Well-coordinated interdisciplinary dental treatments provide the best esthetic, functional, and long-term results for patients. However, the length of such treatment, which may involve orthodontics, ridge augmentation, and dental implants, often deters patients from pursuing them. The two case reports presented here aim to present the advantage of simultaneous orthodontic molar uprighting and ridge augmentation procedures for future implant site development. Selective decortication of the alveolar bone, performed simultaneously with bone grafting, can accelerate the tooth uprighting process and synergistically reduce treatment duration...
May 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/28402351/dimensional-evaluation-of-different-ridge-preservation-techniques-a-randomized-clinical-study
#4
Stefan Fickl, Kai Fischer, Nicole Petersen, Arndt Happe, Markus Schlee, Ulrich Schlagenhauf, Moritz Kebschull
The objective of this study was to quantitatively determine ridge contour changes after different alveolar ridge preservation techniques. An initial total of 40 patients provided a final total of 35 single-gap extraction sites. After tooth removal, the socket was subjected to one of four treatment modalities: placement of a deproteinized bovine bone mineral (DBBM; Endobon) covered with a soft tissue punch from the palate (Tx1); placement of DBBM without soft tissue punch (Tx2); placement of an adsorbable collagen membrane (Osseoguard) covering the DBBM (Tx3); and no additional treatment (control)...
May 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/28402349/partial-extraction-therapies-pet-part-2-procedures-and-technical-aspects
#5
Howard Gluckman, Maurice Salama, Jonathan Du Toit
Part 1 of this series introduced the partial extraction therapies as a group of techniques for ridge preservation at immediate implant placement and beneath pontic sites. The concept proposes a paradigm shift away from extract and augment toward partly retaining the tooth root to preserve the ridge and prevent buccopalatal collapse. The revolutionary socket-shield technique was introduced in 2010; however, there has been no follow-up literature to guide the clinician in terms of procedural steps. While root submergence is well established, the socket-shield and pontic shield are still in their clinical infancy and require long-term clinical data before they can be proposed as routine in everyday implant dentistry...
May 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/28402345/mandibular-regional-anatomical-landmarks-and-clinical-implications-for-ridge-augmentation
#6
Istvan A Urban, Alberto Monje, Hom-Lay Wang, Jaime Lozada, Gabor Gerber, Gabor Baksa
Mandibular ridge augmentation via guided bone regeneration in the atrophic mandible is considered one of the most challenging scenarios for implant-supported oral rehabilitation. Uneventful wound healing has clearly demonstrated its impact on the final regenerative outcome. Soft tissue management must be precise and adequate to attain flap-free wound closure. Accordingly, it demands exhaustive insight and expertise to avoid damaging the neighboring structures. The cadaver study described herein discusses the mandibular morphologic landmarks (ie, musculature, vascularization, innervation, and salivary glands) necessary to safely perform regenerative procedures in the atrophic mandibular ridge, such as vertical ridge augmentation and dental implant surgery...
May 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/28402343/use-of-allograft-with-platelet-concentrate-in-the-treatment-of-multiple-miller-class-iii-gingival-recession-defects-report-of-three-cases
#7
Yumi Ogata, Minh Bui, Terrence J Griffin, Yong Hur
Three patients with multiple Miller Class III recession defects with substantial bone loss were treated with hard tissue augmentation with the goal to prevent future recessions. The surgery involved a full-thickness mucoperiosteal coronally advanced flap, bone grafting, and primary flap closure. Freeze-dried bone allograft (FDBA) in combination with plasma rich in growth factors (PRGF) was grafted during the procedure. After more than 6 months, the treated sites showed soft tissue maturation and esthetic tissue blending...
May 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/28398119/the-association-between-sinus-membrane-thickness-and-membrane-perforation-in-lateral-window-sinus-augmentation-a-retrospective-study
#8
Andrew G Lum, Yumi Ogata, Sarah E Pagni, Yong Hur
BACKGROUND: An association between Schneiderian membrane thickness and membrane perforation was examined in lateral window sinus augmentation. METHODS: The retrospective study reviewed the record of 551 patients who underwent lateral sinus augmentation at Tufts University School of Dental Medicine (TUSDM) from June 1, 2006 to May 31, 2015. Pre-operative cone-beam computed tomography (CBCT) images were analyzed to evaluate a possible association between membrane thickness, residual bone height, and membrane perforation...
February 26, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28393825/a-contemporary-approach-for-treatment-planning-of-horizontally-resorbed-alveolar-ridge-ridge-split-technique-with-simultaneous-implant-placement-using-platelet-rich-fibrin-membrane-application-in-mandibular-anterior-region
#9
Prathahini S Parthiban, R Vijaya Lakshmi, Jaideep Mahendra, K Sreekumar, Ambalavanan Namasivayam
Treatment of edentulous sites with horizontal atrophy represents a clinical situation in which the positioning of endosseous implants might be complex or sometimes impossible without a staged regenerative approach. This case report presents management of horizontally deficient mandibular anterior ridge with a contemporary approach to treatment planning and application of platelet-rich fibrin membrane for ridge split technique and simultaneous implant placement. Implants in anterior mandibular area are considered to be most predictable, stable, with high success rate and patients' satisfaction with implant esthetics...
January 2017: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
https://www.readbyqxmd.com/read/28390758/alternative-distraction-osteogenesis-technique-after-implant-placement-for-alveolar-ridge-augmentation-of-the-maxilla
#10
Renato Luiz Maia Nogueira, Rafael Lima Verde Osterne, Ricardo Teixeira Abreu, Phelype Maia Araújo
An alternative technique to reconstruct atrophic alveolar vertical bone after implant placement is presented. The technique consists of distraction osteogenesis or direct surgical repositioning of an implant-and-bone block segment after segmental osteotomies that can be used in esthetic or unesthetic cases. Initially, casts indicating the implant position are obtained and the future ideal prosthetic position is determined to guide the model surgery. After the model surgery, a new provisional prosthesis is fabricated, and an occlusal splint, which is used as a surgical guide and a device for distraction osteogenesis, is custom fabricated...
March 18, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28378530/guided-bone-regeneration-with-particulate-vs-block-xenogenic-bone-substitutes-a-pilot-cone-beam-computed-tomographic-investigation
#11
Goran I Benic, Daniel S Thoma, Ronald E Jung, Ignacio M Sanz, Silvan Unger, Antonio Cantalapiedra, Christoph H F Hämmerle
AIM: To test whether an equine bone substitute block used for guided bone regeneration (GBR) of peri-implant defects differs from bovine block or particulate bone substitutes regarding the hard and soft tissue contours of the augmented ridge. MATERIAL & METHODS: Two semi-saddle bone defects were prepared in each side of the mandible of eight dogs, and one titanium implant was inserted into every defect. The defects were randomly allocated to receive one of the following treatments: bone augmentation by GBR using (1) particulate deproteinized bovine bone mineral (DBBM) + a collagen membrane (CM), (2) block DBBM + CM, (3) equine bone substitute block + CM, and (4) empty controls...
April 4, 2017: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/28370489/volumetric-changes-and-peri-implant-health-at-implant-sites-with-or-without-soft-tissue-grafting-in-the-esthetic-zone-a-retrospective-case-control-study-with-a-5-year-follow-up
#12
Stefan P Bienz, Ronald E Jung, Vitor M Sapata, Christoph H F Hämmerle, Jürg Hüsler, Daniel S Thoma
OBJECTIVES: To evaluate the volumetric changes and peri-implant health at implant sites with and without previous soft tissue grafting over a 5-year observation period. MATERIAL AND METHODS: In 18 partially edentulous patients, dental implants were placed in the esthetic zone (15-25) with simultaneous guided bone regeneration, followed by submerged healing. During the healing phase, eight patients (test) received a subepithelial connective tissue graft, whereas 10 patients (control) did not receive any soft tissue augmentation...
March 29, 2017: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/28368131/narrow-diameter-implants-dual-function-as-a-tent-pole-for-vertical-ridge-augmentation-and-a-guide-for-definitive-implant-position
#13
Takanori Suzuki, Ismael Khouly, Sang-Choon Cho, Stuart Froum
Vertical bone defects present a challenge for the placement of implants in sufficient bone with proper position for a successful treatment outcome. This case report describes the use of a narrowdiameter (2.2 mm) implant as a tent pole for guided bone regeneration and documents the vertical bone augmentation achieved. In addition, following removal, the narrow-diameter implant served as a guide for the proper positioning and angulation of the final implant and its supporting restoration. The protocol and step-by-step procedure are described...
April 2017: Compendium of Continuing Education in Dentistry
https://www.readbyqxmd.com/read/28366452/lateral-ridge-augmentation-with-bio-oss-alone-or-bio-oss-mixed-with-particulate-autogenous-bone-graft-a-systematic-review
#14
REVIEW
H C Aludden, A Mordenfeld, M Hallman, C Dahlin, T Jensen
The objective of this systematic review was to test the hypothesis of no difference in implant treatment outcomes when using Bio-Oss alone or Bio-Oss mixed with particulate autogenous bone grafts for lateral ridge augmentation. A search of the MEDLINE, Cochrane Library, and Embase databases in combination with a hand-search of relevant journals was conducted. Human studies published in English from 1 January 1990 to 1 May 2016 were included. The search provided 337 titles and six studies fulfilled the inclusion criteria...
March 30, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28363847/ridge-augmentation-with-titanium-mesh-a-case-report
#15
H Jegham, R Masmoudi, H Ouertani, I Blouza, S Turki, M B Khattech
Insufficient bone volume for dental implant placement in the maxillary anterior segment is a constant challenge in oral surgery. Several techniques have been suggested to reconstruct deficient alveolar ridges and to facilitate dental implant placement. These techniques include bone splitting osteotomy, distraction osteogenesis, inlay and onlay bone grafting. Guided bone regeneration (GBR) is also a promising alternative that increases the bone volume by the use of a subperiosteal barrier. AIM: The aim of this case was to demonstrate that the use of rigid titanium occlusive barrier is a reliable alternative to perform a lateral alveolar bone augmentation and treat localized ridge deformities before reaching an ideal implant placement...
March 28, 2017: Journal of Stomatology, Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28361377/alveolar-ridge-preservation-with-autologous-particulated-dentin-a-case-series
#16
Silvio Valdec, Pavla Pasic, Alex Soltermann, Daniel Thoma, Bernd Stadlinger, Martin Rücker
INTRODUCTION: Ridge preservation can be performed with autologous bone, alloplastic bone substitute material or a combination of both. Dentin is similar to bone in its chemical composition. In its use as bone substitute material, it undergoes a remodelling process and transforms to bone. The presented case report introduces a technique in which the extraction socket is augmented with autologous, particulated dentin. MATERIAL AND METHODS: The fractured, non-savable mesial incisor of the upper jaw was carefully extracted in axial direction...
December 2017: International Journal of Implant Dentistry
https://www.readbyqxmd.com/read/28356687/evaluation-of-two-socket-healing-procedures-with-and-without-mesenchymal-stem-cells-a-comparative-study
#17
Abhinav Jain, Mahinder Singh, K P Ganapathy, Vikas Ramola, Deepak Passi, Komal Jain
AIMS AND OBJECTIVES: Successful preservation of the edentulous ridge after extraction may eliminate or reduce the need for ridge augmentation procedures. It is proved that grafting of fresh extraction sockets with bone grafts promotes ridge preservation. An objective method of maintaining height and width of alveolar ridge using mesenchymal stem cells (MSCs) seeded on collagen membrane was implemented in this study. METHODOLOGY: Ten bilaterally symmetrical extraction sockets scheduled for extraction were selected for this study...
July 2016: National Journal of Maxillofacial Surgery
https://www.readbyqxmd.com/read/28337349/a-rational-approach-to-sinus-augmentation-the-low-window-sinus-lift
#18
Terry Zaniol, Alex Zaniol
Sinus augmentation is a well-known approach to treating alveolar bone ridge atrophy in the posterior maxilla. The preparation of the lateral window is crucial. Its size, design, and position in the vestibular sinus wall may affect the intra- and postsurgical complication rates and affect the intrasurgical activity of both surgeons and assistants. The present paper describes a rational technique that also exploits the guided surgery approach for design and preparation of a lateral window for sinus augmentation, the Low Window Sinus Lift...
2017: Case Reports in Dentistry
https://www.readbyqxmd.com/read/28327417/appositional-bone-graft-tunneled-technical-note
#19
Roberto Almeida de Azevedo, Felipe Seoane Matos, Leonardo Morais Godoy Figueiredo
INTRODUCTION: A satisfactory positioning of the dental implants is very important in the cosmetic and functional outcome in this treatment for edentulous. Insertion of an endosseous implant in the correct positioning requires sufficient bone volume. Therefore, bone-grafting procedures are becoming increasingly common, especially for the augmentation of horizontally deficient ridges. PRESENTATION OF CASE: Many patients have been treated with this technique of appositional Bone Graft Tunneled at our clinic since 2005...
February 20, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28326892/clinical-and-histomorphometric-assessment-of-lateral-alveolar-ridge-augmentation-using-a-corticocancellous-freeze-dried-allograft-bone-block
#20
Roya Shariatmadar Ahmadi, Ferena Sayar, Vahid Rakhshan, Babak Iranpour, Jahanfar Jahanbani, Ahmad Toumaj, Nasrin Akhoondi
Horizontal ridge augmentation with allografts has attracted notable attention because of its proper success rate and the lack of disadvantages of autografts. Corticocancellous block allografts have not been adequately studied on humans. Therefore, this study evaluated clinically and histomorphometrically the increase in ridge with after horizontal ridge augmentation using corticocancellous block allografts, and the implant success after 12 to 18 months post-implantation. In 10 implant patients (3 women, 7 men, 45 years old on average), defective maxillary alveolar ridges were horizontally augmented using freeze-dried bone allograft blocks...
March 22, 2017: Journal of Oral Implantology
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