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https://www.readbyqxmd.com/read/28774818/the-protective-effect-of-platelet-released-growth-factors-and-bone-augmentation-bio-oss-%C3%A2-on-ethanol-impaired-osteoblasts
#1
Tolga Taha Sönmez, Andreas Bayer, Tillman Cremer, Jennifer Vanessa Phi Hock, Bernd Lethaus, Nisreen Kweider, Christoph Jan Wruck, Wolf Drescher, Holger Jahr, Sebastian Lippross, Thomas Pufe, Mersedeh Tohidnezhad
BACKGROUND: Chronic alcohol consumption is a known limiting factor for bone healing. One promising strategy to improve bone augmentation techniques with Bio-Oss(®) in oral and maxillofacial surgery might be the supportive application of platelet-concentrated biomaterials as platelet-released growth factor (PRGF). To address this matter, we performed an in vitro study investigating the protective effects of PRGF and Bio-Oss(®) in ethanol (EtOH) treated osteoblasts. METHODS: The SAOS-2 osteosarcoma cell line, with and without EtOH pretreatment was used...
July 31, 2017: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://www.readbyqxmd.com/read/28757934/applications-of-biomaterials-for-bone-augmentation-of-jaws-clinical-outcomes-and-in-vitro-studies
#2
L Tettamanti, M Andreasi Bassi, G Trapella, V Candotto, A Tagliabue
Partially or totally edentulous jaws frequently undergoes from moderate to severe bone atrophy with problems of prosthetic rehabilitation. The inability to make a prosthetic rehabilitation on implants may led to the use of a partial or total removable denture with difficulties in eating and speech, ulcerations of the oral mucosa and loss of facial vertical dimension. These problems may be solved performing bone augmentation procedures. Bone grafts and distraction osteogenesis brought implant dentistry from an experimental practice to become a consolidate dental procedure...
January 2017: Oral & Implantology
https://www.readbyqxmd.com/read/28732677/assessment-of-bone-repair-in-critical-size-defect-in-the-calvarium-of-rats-after-the-implantation-of-tricalcium-phosphate-beta-%C3%AE-tcp
#3
Leonardo de Freitas Silva, Erik Neiva Ribeiro de Carvalho Reis, Tânia Aparecida Barbara, João Paulo Bonardi, Idelmo Rangel Garcia, Paulo Sérgio Perri de Carvalho, Daniela Ponzoni
OBJECTIVES: Evaluating the osteoconductive property of tricalcium phosphate beta (β-TCP) in comparison to that of inorganic bovine bone for repair in a critical-size defect in the rat calvarium. MATERIALS AND METHODS: Critical-size defects of 7mm were made with a trephine in the calvaria of 48 Wistar rats. The animals were divided into four groups, and the defects in each group were filled with tricalcium phosphate beta (β-TCP), inorganic bovine bone (Bio-Oss), autogenous bone, or left empty...
July 18, 2017: Acta Histochemica
https://www.readbyqxmd.com/read/28731486/demineralized-dentin-and-enamel-matrices-as-suitable-substrates-for-bone-regeneration
#4
Nina Bono, Paolo Tarsini, Gabriele Candiani
BACKGROUND: In recent decades, tooth derivatives such as dentin (D) and enamel (E) have been considered as potential graft biomaterials to treat bone defects. This study aimed to investigate the effects of demineralization on the physical-chemical and biological behavior of D and E. METHODS: Human D and E were minced into particles (Ø<1 mm), demineralized and sterilized. Thorough physical-chemical and biochemical characterizations of native and demineralized materials were performed by SEM and EDS analysis and ELISA kits to determine mineral, collagen type I and BMP-2 contents...
July 20, 2017: Journal of Applied Biomaterials & Functional Materials
https://www.readbyqxmd.com/read/28655570/new-nano-hydroxyapatite-in-bone-defect-regeneration-a-histological-study-in-rats
#5
Paweł Kubasiewicz-Ross, Jakub Hadzik, Julia Seeliger, Karol Kozak, Kamil Jurczyszyn, Hanna Gerber, Marzena Dominiak, Christiane Kunert-Keil
Many types of bone substitute materials are available on the market. Researchers are refining new bone substitutes to make them comparable to autologous grafting materials in treatment of bone defects. The purpose of the study was to evaluate the osseoconductive potential and bone defect regeneration in rat calvaria bone defects treated with new synthetic nano-hydroxyapatite. The study was performed on 30 rats divided into 5 equal groups. New preproduction of experimental nano-hydroxyapatite material by NanoSynHap (Poznań, Poland) was tested and compared with commercially available materials...
September 2017: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://www.readbyqxmd.com/read/28613059/-experimental-study-of-transforming-growth-factor-%C3%AE-3-combined-with-dental-pulp-stem-cells-in-promoting-the-implant-s-osseointegration
#6
T Wang, Huojia Muhetaer, J Li
Objective: To investigate the effect of transforming growth factor-β3 (TGF-β3) and dental pulp stem cells (DPSC) in promoting the implant's osteointegration. Methods: Thirty-three New Zealand white rabbits were randomly divided into phosphate buffer saline (PBS) group, DPSC group and TGF-β3 + DPSC group (12 rabbits/group). Two teeth from the rabbits's mandibular incisors or molars were pulled out randomly, then implant were placed in the tooth extraction site immediately. In PBS group, the implant area was filled with Bio-Oss powder 0...
June 9, 2017: Zhonghua Kou Qiang Yi Xue za Zhi, Zhonghua Kouqiang Yixue Zazhi, Chinese Journal of Stomatology
https://www.readbyqxmd.com/read/28609508/evaluation-of-the-bone-regenerating-effects-of-two-anorganic-bovine-bone-grafts-in-a-critical-sized-alveolar-ridge-defect-model
#7
David M Kim, Heather Hong, Jerry Ching-Yi Lin, Myron Nevins
A preclinical trial was conducted to treat 54 mandibular critical-sized alveolar ridge defects in 27 canines. Each hemimandible was randomized to be treated with two different anorganic bovine bone grafts (group A = InterOss [SigmaGraft]; group B = Bio-Oss [Geistlich]) or negative control (group C = empty defect) followed by a 4-, 8-, or 12-week observation period. Microcomputed tomography, histology, histopathology, and histomorphometric analyses were performed to evaluate the safety and efficacy of these treatments...
July 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/28609506/early-orthodontic-tooth-movement-into-regenerative-bony-defects-a-case-report
#8
Hui-Chen Tsai, Chung-Chen Jane Yao, Man-Ying Wong
Early orthodontic tooth movement following regenerative surgery is controversial. In this case, during protraction of the maxillary right first premolar to substitute for the long-term missing maxillary right canine, Bio-Oss and Bio-Gide were used for lateral ridge augmentation at the area of the maxillary right lateral incisor and to cover the denuded surface at the buccal side of the first premolar. Orthodontic tooth movement (OTM) commenced 2 weeks after regenerative surgery. After 8 months, new bone formation was observed on the root surface of the first premolar during implant surgery...
July 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/28584862/corrigendum-to-comparative-study-on-the-efficacy-of-anorganic-bovine-bone-bio-oss-and-nanocrystalline-hydroxyapatite-ostim-in-maxillary-sinus-floor-augmentation
#9
Adileh Shirmohammadi, Leila Roshangar, Mohammad Taghi Chitsazi, Reza Pourabbas, Masoumeh Faramarzi, Nasrin Rahmanpour
[This corrects the article DOI: 10.1155/2014/967091.].
2017: International Scholarly Research Notices
https://www.readbyqxmd.com/read/28545806/a-systematic-review-and-meta-analysis-of-long-term-studies-five-or-more-years-assessing-maxillary-sinus-floor-augmentation
#10
REVIEW
T Starch-Jensen, H Aludden, M Hallman, C Dahlin, A-E Christensen, A Mordenfeld
The objective was to test the hypothesis of no difference in long-term (≥5 years) implant treatment outcomes after maxillary sinus floor augmentation (MSFA) with autogenous bone graft compared to a mixture of autogenous bone graft and bone substitutes or bone substitutes alone. A MEDLINE (PubMed), Embase, and Cochrane Library search in combination with a hand-search of relevant journals was conducted. Human studies published in English between January 1, 1990 and October 1, 2016 were included. Nine studies fulfilled the inclusion criteria...
May 22, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28494043/maxillary-sinus-floor-augmentation-using-xenograft-gene-expression-and-histologic-analysis
#11
Jaijam Suwanwela, Dollaya Puangchaipruk, Kamolporn Wattanasirmkit, Paksinee Kamolratanakul, Pornchai Jansisyanont
PURPOSE: Many histologic and histomorphometric studies as well as systematic reviews have shown the clinical success of the use of anorganic bovine bone (ABB, Bio-Oss) in maxillary sinus floor augmentation (MSFA). The molecular processes involved in bone healing are, however, still unknown. The aims of this study were to explore gene expression associated with bone remodeling and inflammation in MSFA sites. MATERIALS AND METHODS: The mRNA expression levels of runt related transcription factor 2 (RUNX2), receptor activator of NF-kB ligand (RANKL), osteoprotegerin (OPG), matrix metallopeptidase 9 (MMP-9), tartrate-resistance acid phosphatase (TRAP), and interleukin-1beta (IL-1β), as well as the ratio of RANKL/OPG were compared between alveolar bone of a group after MSFA with ABB and a maxillary posterior edentulous bone group...
May 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28366452/lateral-ridge-augmentation-with-bio-oss-alone-or-bio-oss-mixed-with-particulate-autogenous-bone-graft-a-systematic-review
#12
REVIEW
H C Aludden, A Mordenfeld, M Hallman, C Dahlin, T Jensen
The objective of this systematic review was to test the hypothesis of no difference in implant treatment outcomes when using Bio-Oss alone or Bio-Oss mixed with particulate autogenous bone grafts for lateral ridge augmentation. A search of the MEDLINE, Cochrane Library, and Embase databases in combination with a hand-search of relevant journals was conducted. Human studies published in English from 1 January 1990 to 1 May 2016 were included. The search provided 337 titles and six studies fulfilled the inclusion criteria...
March 30, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28301383/radiographic-and-histological-evaluation-of-the-healing-of-extraction-sockets-filled-with-bovine-derived-xenograft-an-experimental-study-in-rats
#13
Fengjuan Zhou, Xiaofei Zheng, Meng Xie, Anchun Mo, Hongkun Wu
AIM: To evaluate the microenvironment changes in the sockets substituted with bovine-derived xenografts during the early healing period. MATERIALS AND METHODS: After extraction of the right maxillary incisor of Sprague Dawley rats, 48 rats were randomly divided into 2 groups. The extraction sockets of the test group were filled with Bio-Oss, whereas the control group was allowed to heal without intervention. The bone quality of the extraction sockets was observed through micro-CT and immunohistochemistry...
June 2017: Implant Dentistry
https://www.readbyqxmd.com/read/28299254/volumetric-analysis-of-bone-substitute-material-performance-within-the-human-sinus-cavity-of-former-head-and-neck-cancer-patients-a-prospective-randomized-clinical-trial
#14
Jonas Lorenz, Kathrin Eichler, Mike Barbeck, Henriette Lerner, Stefan Stübinger, Catherine Seipel, Thomas J Vogl, Adorján F Kovács, Shahram Ghanaati, Robert A Sader
BACKGROUND: In numerous animal and human studies, it could be detected that in bone augmentation procedures, material's physicochemical characteristics can influence the cellular inflammatory pattern and therefore the integration in the host tissue. Histological, histomorphometrical, and clinical analyses of the integration of the biomaterial in the surrounding tissue are well established methodologies; however, they do not make a statement on volume and density changes of the augmented biomaterial...
July 2016: Annals of Maxillofacial Surgery
https://www.readbyqxmd.com/read/28299252/secondary-closure-of-alveolar-cleft-with-resorbable-collagen-membrane-and-a-combination-of-intraoral-autogenous-bone-graft-and-deproteinized-anorganic-bovine-bone
#15
Lobna Abdel Aziz Aly, Nelly Hammouda
OBJECTS: Secondary alveolar bone grafting is a method that enables an excellent oral rehabilitation of the patients having alveolar cleft. The aim of this work is to report the closure of the alveolar cleft with the use of harvested autogenous bone graft combined with deproteinized anorganic bovine bone (Bio-Oss) under local anesthesia. SETTINGS AND SAMPLE POPULATION: Nine patients with age range, 8-11 years were consulted for their unilateral alveolar cleft. MATERIALS AND METHODS: A combination of symphyseal bone and deproteinized bovine bone mineral (DBBM) was placed into the alveolar cleft defect...
July 2016: Annals of Maxillofacial Surgery
https://www.readbyqxmd.com/read/28288022/bone-healing-evaluation-in-critical-size-defects-treated-with-xenogenous-bone-plus-porcine-collagen
#16
Juceléia Maciel, Gustavo Antonio Correa Momesso, Gabriel Ramalho-Ferreira, Renata Bianco Consolaro, Paulo Sérgio Perri de Carvalho, Leonardo Perez Faverani, Ana Paula Farnezi Bassi
PURPOSE: This study aimed to evaluate the osteoconductive features of Bio-Oss Collagen in large critical-size defects (8 mm). MATERIALS AND METHODS: Thirty-six adult Wistar Albinus male adult rats were carried out a critical-size defect with a trephine bur of 8 mm in the calvaria. Groups were divided depending on the filling biomaterial as follows: group BO: Bio-Oss (n = 18); group BOC: Bio-Oss Collagen (n = 18). After 7, 30, and 60 days, 6 rats of each group were euthanized with anesthetic overdose...
April 2017: Implant Dentistry
https://www.readbyqxmd.com/read/28203026/-histomorphometric-evaluation-of-ridge-preservation-after-molar-tooth-extraction
#17
Y L Zhan, W J Hu, T Xu, M Zhen, R F Lu
OBJECTIVE: To evaluate bone formation in human extraction sockets with absorbed surrounding walls augmented with Bio-Oss and Bio-Gide after a 6-month healing period by histologic and histomorphometric analyses. METHODS: Six fresh molar tooth extraction sockets in 6 patients who required periodontally compromised moral tooth extraction were included in this study. The six fresh extraction sockets were grafted with Bio-Oss particle covered with Bio-Gide. The 2.8 mm×6...
February 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28186709/in-vitro-evaluation-of-the-biological-compatibility-and-antibacterial-activity-of-a-bone-substitute-material-consisting-of-silver-doped-hydroxyapatite-and-bio-oss-%C3%A2
#18
Jingjue Gong, Lei Yang, Qi He, Ting Jiao
This study evaluated biological compatibility and antibacterial activity of a bone substitute material consisting of silver-doped hydroxyapatite (AgHA) and Bio-Oss(®) with different mixture ratios in vitro and investigated its antibacterial mechanism. AgHA was synthesized by a chemical precipitation method. After characterization, AgHA was mixed with Bio-Oss(®) at three ratios: 1:1, 1:2, and 1:4 by weight. Then, Porphyromonas gingivalis (Pg) and Fusobacterium nucleatum (Fn) were used to test the antibacterial activity of the mixture...
February 10, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28027692/comparison-of-3d-printed-poly-%C3%A9-caprolactone-scaffolds-functionalized-with-tricalcium-phosphate-hydroxyapatite-bio-oss-or-decellularized-bone-matrix
#19
Ethan Nyberg, Alexandra Rindone, Amir Dorafshar, Warren L Grayson
Three-dimensional (3D)-printing facilitates rapid, custom manufacturing of bone scaffolds with a wide range of material choices. Recent studies have demonstrated the potential for 3D-printing bioactive (i.e., osteo-inductive) scaffolds for use in bone regeneration applications. In this study, we 3D-printed porous poly-ɛ-caprolactone (PCL) scaffolds using a fused deposition modeling (FDM) process and functionalized them with mineral additives that have been widely used commercially and clinically: tricalcium phosphate (TCP), hydroxyapatite (HA), Bio-Oss (BO), or decellularized bone matrix (DCB)...
February 7, 2017: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/27987520/-dental-implantation-and-soft-tissue-augmentation-after-ridge-preservation-in-a-molar-site-a-case-report
#20
L P Zhao, Y L Zhan, W J Hu, H J Wang, Y P Wei, M Zhen, T Xu, Y S Liu
For ideal implant rehabilitation, an adequate bone volume, optical implant position, and stable and healthy soft tissue are required. The reduction of alveolar bone and changes in its morphology subsequent to tooth extraction will result in insufficient amount of bone and adversely affect the ability to optimally place dental implants in edentulous sites. Preservation of alveolar bone volume through ridge preservation has been demonstrated to reduce the vertical and horizontal contraction of the alveolar bone crest after tooth extraction and reduce the need for additional bone augmentation procedures during implant placement...
December 18, 2016: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
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