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https://www.readbyqxmd.com/read/28613059/-experimental-study-of-transforming-growth-factor-%C3%AE-3-combined-with-dental-pulp-stem-cells-in-promoting-the-implant-s-osseointegration
#1
T Wang, Huojia Muhetaer, J Li
Objective: To investigate the effect of transforming growth factor-β3 (TGF-β3) and dental pulp stem cells (DPSC) in promoting the implant's osteointegration. Methods: Thirty-three New Zealand white rabbits were randomly divided into phosphate buffer saline (PBS) group, DPSC group and TGF-β3 + DPSC group (12 rabbits/group). Two teeth from the rabbits's mandibular incisors or molars were pulled out randomly, then implant were placed in the tooth extraction site immediately. In PBS group, the implant area was filled with Bio-Oss powder 0...
June 9, 2017: Zhonghua Kou Qiang Yi Xue za Zhi, Zhonghua Kouqiang Yixue Zazhi, Chinese Journal of Stomatology
https://www.readbyqxmd.com/read/28609508/evaluation-of-the-bone-regenerating-effects-of-two-anorganic-bovine-bone-grafts-in-a-critical-sized-alveolar-ridge-defect-model
#2
David M Kim, Heather Hong, Jerry Ching-Yi Lin, Myron Nevins
A preclinical trial was conducted to treat 54 mandibular critical-sized alveolar ridge defects in 27 canines. Each hemimandible was randomized to be treated with two different anorganic bovine bone grafts (group A = InterOss [SigmaGraft]; group B = Bio-Oss [Geistlich]) or negative control (group C = empty defect) followed by a 4-, 8-, or 12-week observation period. Microcomputed tomography, histology, histopathology, and histomorphometric analyses were performed to evaluate the safety and efficacy of these treatments...
July 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/28609506/early-orthodontic-tooth-movement-into-regenerative-bony-defects-a-case-report
#3
Hui-Chen Tsai, Chung-Chen Jane Yao, Man-Ying Wong
Early orthodontic tooth movement following regenerative surgery is controversial. In this case, during protraction of the maxillary right first premolar to substitute for the long-term missing maxillary right canine, Bio-Oss and Bio-Gide were used for lateral ridge augmentation at the area of the maxillary right lateral incisor and to cover the denuded surface at the buccal side of the first premolar. Orthodontic tooth movement (OTM) commenced 2 weeks after regenerative surgery. After 8 months, new bone formation was observed on the root surface of the first premolar during implant surgery...
July 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/28584862/corrigendum-to-comparative-study-on-the-efficacy-of-anorganic-bovine-bone-bio-oss-and-nanocrystalline-hydroxyapatite-ostim-in-maxillary-sinus-floor-augmentation
#4
Adileh Shirmohammadi, Leila Roshangar, Mohammad Taghi Chitsazi, Reza Pourabbas, Masoumeh Faramarzi, Nasrin Rahmanpour
[This corrects the article DOI: 10.1155/2014/967091.].
2017: International Scholarly Research Notices
https://www.readbyqxmd.com/read/28545806/a-systematic-review-and-meta-analysis-of-long-term-studies-five-or-more-years-assessing-maxillary-sinus-floor-augmentation
#5
REVIEW
T Starch-Jensen, H Aludden, M Hallman, C Dahlin, A-E Christensen, A Mordenfeld
The objective was to test the hypothesis of no difference in long-term (≥5 years) implant treatment outcomes after maxillary sinus floor augmentation (MSFA) with autogenous bone graft compared to a mixture of autogenous bone graft and bone substitutes or bone substitutes alone. A MEDLINE (PubMed), Embase, and Cochrane Library search in combination with a hand-search of relevant journals was conducted. Human studies published in English between January 1, 1990 and October 1, 2016 were included. Nine studies fulfilled the inclusion criteria...
May 22, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28494043/maxillary-sinus-floor-augmentation-using-xenograft-gene-expression-and-histologic-analysis
#6
Jaijam Suwanwela, Dollaya Puangchaipruk, Kamolporn Wattanasirmkit, Paksinee Kamolratanakul, Pornchai Jansisyanont
PURPOSE: Many histologic and histomorphometric studies as well as systematic reviews have shown the clinical success of the use of anorganic bovine bone (ABB, Bio-Oss) in maxillary sinus floor augmentation (MSFA). The molecular processes involved in bone healing are, however, still unknown. The aims of this study were to explore gene expression associated with bone remodeling and inflammation in MSFA sites. MATERIALS AND METHODS: The mRNA expression levels of runt related transcription factor 2 (RUNX2), receptor activator of NF-kB ligand (RANKL), osteoprotegerin (OPG), matrix metallopeptidase 9 (MMP-9), tartrate-resistance acid phosphatase (TRAP), and interleukin-1beta (IL-1β), as well as the ratio of RANKL/OPG were compared between alveolar bone of a group after MSFA with ABB and a maxillary posterior edentulous bone group...
May 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28366452/lateral-ridge-augmentation-with-bio-oss-alone-or-bio-oss-mixed-with-particulate-autogenous-bone-graft-a-systematic-review
#7
REVIEW
H C Aludden, A Mordenfeld, M Hallman, C Dahlin, T Jensen
The objective of this systematic review was to test the hypothesis of no difference in implant treatment outcomes when using Bio-Oss alone or Bio-Oss mixed with particulate autogenous bone grafts for lateral ridge augmentation. A search of the MEDLINE, Cochrane Library, and Embase databases in combination with a hand-search of relevant journals was conducted. Human studies published in English from 1 January 1990 to 1 May 2016 were included. The search provided 337 titles and six studies fulfilled the inclusion criteria...
March 30, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28301383/radiographic-and-histological-evaluation-of-the-healing-of-extraction-sockets-filled-with-bovine-derived-xenograft-an-experimental-study-in-rats
#8
Fengjuan Zhou, Xiaofei Zheng, Meng Xie, Anchun Mo, Hongkun Wu
AIM: To evaluate the microenvironment changes in the sockets substituted with bovine-derived xenografts during the early healing period. MATERIALS AND METHODS: After extraction of the right maxillary incisor of Sprague Dawley rats, 48 rats were randomly divided into 2 groups. The extraction sockets of the test group were filled with Bio-Oss, whereas the control group was allowed to heal without intervention. The bone quality of the extraction sockets was observed through micro-CT and immunohistochemistry...
June 2017: Implant Dentistry
https://www.readbyqxmd.com/read/28299254/volumetric-analysis-of-bone-substitute-material-performance-within-the-human-sinus-cavity-of-former-head-and-neck-cancer-patients-a-prospective-randomized-clinical-trial
#9
Jonas Lorenz, Kathrin Eichler, Mike Barbeck, Henriette Lerner, Stefan Stübinger, Catherine Seipel, Thomas J Vogl, Adorján F Kovács, Shahram Ghanaati, Robert A Sader
BACKGROUND: In numerous animal and human studies, it could be detected that in bone augmentation procedures, material's physicochemical characteristics can influence the cellular inflammatory pattern and therefore the integration in the host tissue. Histological, histomorphometrical, and clinical analyses of the integration of the biomaterial in the surrounding tissue are well established methodologies; however, they do not make a statement on volume and density changes of the augmented biomaterial...
July 2016: Annals of Maxillofacial Surgery
https://www.readbyqxmd.com/read/28299252/secondary-closure-of-alveolar-cleft-with-resorbable-collagen-membrane-and-a-combination-of-intraoral-autogenous-bone-graft-and-deproteinized-anorganic-bovine-bone
#10
Lobna Abdel Aziz Aly, Nelly Hammouda
OBJECTS: Secondary alveolar bone grafting is a method that enables an excellent oral rehabilitation of the patients having alveolar cleft. The aim of this work is to report the closure of the alveolar cleft with the use of harvested autogenous bone graft combined with deproteinized anorganic bovine bone (Bio-Oss) under local anesthesia. SETTINGS AND SAMPLE POPULATION: Nine patients with age range, 8-11 years were consulted for their unilateral alveolar cleft. MATERIALS AND METHODS: A combination of symphyseal bone and deproteinized bovine bone mineral (DBBM) was placed into the alveolar cleft defect...
July 2016: Annals of Maxillofacial Surgery
https://www.readbyqxmd.com/read/28288022/bone-healing-evaluation-in-critical-size-defects-treated-with-xenogenous-bone-plus-porcine-collagen
#11
Juceléia Maciel, Gustavo Antonio Correa Momesso, Gabriel Ramalho-Ferreira, Renata Bianco Consolaro, Paulo Sérgio Perri de Carvalho, Leonardo Perez Faverani, Ana Paula Farnezi Bassi
PURPOSE: This study aimed to evaluate the osteoconductive features of Bio-Oss Collagen in large critical-size defects (8 mm). MATERIALS AND METHODS: Thirty-six adult Wistar Albinus male adult rats were carried out a critical-size defect with a trephine bur of 8 mm in the calvaria. Groups were divided depending on the filling biomaterial as follows: group BO: Bio-Oss (n = 18); group BOC: Bio-Oss Collagen (n = 18). After 7, 30, and 60 days, 6 rats of each group were euthanized with anesthetic overdose...
April 2017: Implant Dentistry
https://www.readbyqxmd.com/read/28203026/-histomorphometric-evaluation-of-ridge-preservation-after-molar-tooth-extraction
#12
Y L Zhan, W J Hu, T Xu, M Zhen, R F Lu
OBJECTIVE: To evaluate bone formation in human extraction sockets with absorbed surrounding walls augmented with Bio-Oss and Bio-Gide after a 6-month healing period by histologic and histomorphometric analyses. METHODS: Six fresh molar tooth extraction sockets in 6 patients who required periodontally compromised moral tooth extraction were included in this study. The six fresh extraction sockets were grafted with Bio-Oss particle covered with Bio-Gide. The 2.8 mm×6...
February 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28186709/in-vitro-evaluation-of-the-biological-compatibility-and-antibacterial-activity-of-a-bone-substitute-material-consisting-of-silver-doped-hydroxyapatite-and-bio-oss-%C3%A2
#13
Jingjue Gong, Lei Yang, Qi He, Ting Jiao
This study evaluated biological compatibility and antibacterial activity of a bone substitute material consisting of silver-doped hydroxyapatite (AgHA) and Bio-Oss(®) with different mixture ratios in vitro and investigated its antibacterial mechanism. AgHA was synthesized by a chemical precipitation method. After characterization, AgHA was mixed with Bio-Oss(®) at three ratios: 1:1, 1:2, and 1:4 by weight. Then, Porphyromonas gingivalis (Pg) and Fusobacterium nucleatum (Fn) were used to test the antibacterial activity of the mixture...
February 10, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28027692/comparison-of-3d-printed-poly-%C3%A9-caprolactone-scaffolds-functionalized-with-tricalcium-phosphate-hydroxyapatite-bio-oss-or-decellularized-bone-matrix
#14
Ethan Nyberg, Alexandra Rindone, Amir Dorafshar, Warren L Grayson
Three-dimensional (3D)-printing facilitates rapid, custom manufacturing of bone scaffolds with a wide range of material choices. Recent studies have demonstrated the potential for 3D-printing bioactive (i.e., osteo-inductive) scaffolds for use in bone regeneration applications. In this study, we 3D-printed porous poly-ɛ-caprolactone (PCL) scaffolds using a fused deposition modeling (FDM) process and functionalized them with mineral additives that have been widely used commercially and clinically: tricalcium phosphate (TCP), hydroxyapatite (HA), Bio-Oss (BO), or decellularized bone matrix (DCB)...
February 7, 2017: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/27987520/-dental-implantation-and-soft-tissue-augmentation-after-ridge-preservation-in-a-molar-site-a-case-report
#15
L P Zhao, Y L Zhan, W J Hu, H J Wang, Y P Wei, M Zhen, T Xu, Y S Liu
For ideal implant rehabilitation, an adequate bone volume, optical implant position, and stable and healthy soft tissue are required. The reduction of alveolar bone and changes in its morphology subsequent to tooth extraction will result in insufficient amount of bone and adversely affect the ability to optimally place dental implants in edentulous sites. Preservation of alveolar bone volume through ridge preservation has been demonstrated to reduce the vertical and horizontal contraction of the alveolar bone crest after tooth extraction and reduce the need for additional bone augmentation procedures during implant placement...
December 18, 2016: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/27934787/long-term-biological-performance-of-injectable-and-degradable-calcium-phosphate-cement
#16
Eline-Claire Grosfeld, Jan Willem M Hoekstra, Ralf-Peter Herber, Dietmar J O Ulrich, John A Jansen, Jeroen J J P van den Beucken
Enhancing degradation of poorly degrading injectable calcium phosphate (CaP) cements (CPCs) can be achieved by adding poly(lactic-co-glycolic acid) (PLGA) microparticles, generating porosity after polymer degradation. CPC-PLGA has proven to be biodegradable, although its long-term biological performance is still unknown. Optimization of injectability could be achieved via addition of carboxymethyl cellulose (CMC). Here, we evaluated the long-term in vivo performance of CPC-PLGA with or without the lubricant CMC in comparison to the devitalized bovine bone mineral (DBBM) predicate device Bio-Oss(®)...
December 9, 2016: Biomedical Materials
https://www.readbyqxmd.com/read/27889939/the-performance-of-cpc-plga-and-bio-oss-%C3%A2-for-bone-regeneration-in-healthy-and-osteoporotic-rats
#17
Claire I A van Houdt, Dietmar J O Ulrich, John A Jansen, Jeroen J J P van den Beucken
The current study aimed to evaluate the biological performance of calcium phosphate cement (CPC) with polylactic-co-glycolic acid (PLGA) micro-particles and Bio-Oss(®) in ovariectomized and healthy rats. Thirty-two Wistar rats received alternating experimental CPC/PLGA and Bio-Oss(®) in femoral condyle defects in both femurs 6 weeks after ovariectomy (OVX, n = 16) or sham operation (SHAM, n = 16). Six weeks after OVX or SHAM surgery, bone morphology was analyzed by in vivo computed tomography (CT) to confirm osteoporotic bone condition...
November 27, 2016: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/27857771/a-histologic-histomorphometric-and-radiographic-comparison-between-two-complexes-of-cenoboen-cenomembrane-and-bio-oss-bio-gide-in-lateral-ridge-augmentation-a-clinical-trial
#18
Babak Amoian, Ehsan Moudi, Maryam Seyed Majidi, S M Ali Tabatabaei
BACKGROUND: Several grafting materials have been used for alveolar ridge augmentation. The literature lacks researches to compare CenoBone to other grafting materials. The aim of this study was to compare CenoBone/CenoMembrane complex to Bio-Oss/Bio-Gide complex in lateral alveolar bone augmentation in terms of radiographic, histologic, and histomorphometric parameters. MATERIALS AND METHODS: In this randomized controlled trial, ten patients who needed lateral ridge augmentation were selected and augmentations were done using either of CenoBone/CenoMembrane or Bio-Oss/Bio-Gide complexes...
September 2016: Dental Research Journal
https://www.readbyqxmd.com/read/27815999/bone-regeneration-induced-by-a-3d-architectured-hydrogel-in-a-rat-critical-size-calvarial-defect
#19
P Lohmann, A Willuweit, A T Neffe, S Geisler, T P Gebauer, S Beer, H H Coenen, H Fischer, B Hermanns-Sachweh, A Lendlein, N J Shah, F Kiessling, K-J Langen
Bone regeneration can be stimulated by implantation of biomaterials, which is especially important for larger bone defects. Here, healing potency of the porous ArcGel was evaluated in a critical-size calvarial bone defect in rats in comparison with clinical standard autologous bone and Bio-Oss(®) Collagen (BioOss), a bone graft material frequently used in clinics. Bone healing and metabolic processes involved were monitored longitudinally by [(18)F]-fluoride and [(18)F]-FDG μ-PET/CT 1d, 3d, 3w, 6w, and 12w post implantation...
October 28, 2016: Biomaterials
https://www.readbyqxmd.com/read/27747635/immediate-placement-and-provisionalization-of-an-implant-after-removal-of-an-impacted-maxillary-canine-two-case-reports
#20
Elise G Zuiderveld, Henny J A Meijer, Arjan Vissink, Gerry M Raghoebar
Single immediate implant replacement is accompanied by excellent survival rates and a favorable esthetic outcome. The objective of this report was to describe a surgical approach for removal of a buccal or palatally located impacted secondary canine, combined with extraction of the failing primary canine, and immediate placement and provisionalization of an implant. A window technique was applied for surgical removal of the impacted canine. The alveolar crest was preserved. After extraction of the primary canine, the implant was inserted with primary stability...
December 2015: International Journal of Implant Dentistry
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