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https://www.readbyqxmd.com/read/29759309/efficacy-of-stem-cells-in-maxillary-sinus-floor-augmentation-systematic-review-and-meta-analysis
#1
REVIEW
T C Niño-Sandoval, B C Vasconcelos, S L D Moraes, C A A Lemos, E P Pellizzer
The aim of this review was to test the hypothesis of no difference in the efficacy of bone regeneration when using stem cells in maxillary sinus floor augmentation surgery in comparison to other grafts. Nine randomized clinical trials and one follow-up study involving human subjects were identified through a search of the PubMed/MEDLINE, Scopus, Cochrane, and Web of Science databases, supplemented by a hand search. No significant difference between groups was found for the implant survival rate, increase in bone height, marginal bone loss following implant placement, or new bone formation...
May 11, 2018: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29724045/histological-evaluation-of-the-healing-process-of-various-bone-graft-materials-after-engraftment-into-the-human-body
#2
Sang Hyun Jo, Young-Kyun Kim, Yong-Hoon Choi
The purpose of this study was to measure the level of new bone formation induced by various bone graft materials to provide clinicians with more choices. The samples were divided into three groups: group 1 ( n = 9: allograft + xenograft, DBX® , San Francisco, CA, USA + Bio-Oss® , Princeton, NJ, USA), group 2 ( n = 10: xenograft, Bio-Oss® ), and group 3 ( n = 8: autogenous tooth bone graft, AutoBT® , Korea Tooth Bank, Seoul, Korea). The average duration of evaluation was 9.56, 2...
May 2, 2018: Materials
https://www.readbyqxmd.com/read/29707988/purification-processes-of-xenogeneic-bone-substitutes-and-their-impact-on-tissue-reactions-and-regeneration
#3
Zeljka Perić Kačarević, Faraz Kavehei, Alireza Houshmand, Jörg Franke, Ralf Smeets, Denis Rimashevskiy, Sabine Wenisch, Reinhard Schnettler, Ole Jung, Mike Barbeck
Xenogeneic bone substitute materials are widely used in oral implantology. Prior to their clinical use, purification of the former bone tissue has to be conducted to ensure the removal of immunogenic components and pathogens. Different physicochemical methods are applied for purification of the donor tissue, and temperature treatment is one of these methods. Differences in these methods and especially the application of different temperatures for purification may lead to different material characteristics, which may influence the tissue reactions to these materials and the related (bone) healing process...
April 1, 2018: International Journal of Artificial Organs
https://www.readbyqxmd.com/read/29690697/-experimental-study-on-the-transforming-growth-factor-%C3%AE-3-combined-with-dental-pulp-stem-cells-in-early-bone-integration-of-implant
#4
Ababaikeli Guzalinuer, Huojia Muhetaer, H Wu, Abudureheman Paerhati
Objective: To establish the experimental model of rabbit mandibular anterior implant repair and evaluate the effects of transforming growth factor (TGF)-β3 and dental pulp stem cells (DPSC) in promoting the bone integration of implant. Methods: The New Zealand rabbits were randomly divided into experimental group, control group and blank group (6 rabbits for each group) . In the experimental group, the implant area was filled with the mixture of TGF-β3, DPSC and Bio-oss powder. In the control group, the implant area was filled with the mixture of DPSC and Bio-oss powder...
April 9, 2018: Zhonghua Kou Qiang Yi Xue za Zhi, Zhonghua Kouqiang Yixue Zazhi, Chinese Journal of Stomatology
https://www.readbyqxmd.com/read/29682529/effect-of-semelil-an-herbal-selenium-based-medicine-on-new-bone-formation-in-calvarium-of-rabbits
#5
Amir Alireza Rasouli-Ghahroudi, Amirreza Rokn, Mohammad Abdollahi, Fatemeh Mashhadi-Abbas, Siamak Yaghobee
Background: This study aims to analyze the effect of Semelil, an herbal selenium-based medicine, on osteogenesis in rabbit calvarium defects. Methods: Four identical bony defects (8 mm) were created in the calvarium of 16 New Zealand male rabbits and filled randomly with xenogenic bone substitute material (Bio-Oss®) and semelil herbal drug (ANGIPARS™). One site was filled with Bio-Oss (B); the second site was treated with ANGIPARS (A); the third site was treated with ANGIPARS + Bio-Oss (AB); and the fourth site was left as untreated control (C) and defects were left unfilled...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29675998/biomaterial-granules-used-for-filling-bone-defects-constitute-3d-scaffolds-porosity-microarchitecture-and-molecular-composition-analyzed-by-microct-and-raman-microspectroscopy
#6
Baptiste Arbez, Jean-Daniel Kün-Darbois, Thierry Convert, Bernard Guillaume, Philippe Mercier, Laurent Hubert, Daniel Chappard
Biomaterials are used in the granular form to fill small bone defects. Granules can be prepared with a grinder from trabecular bone samples or provided as synthetic biomaterials by industry. Granules occupy the 3D-space and create a macroporosity allowing invasion of vascular and bone cells when the inter-granular pores are larger than 300 µm. We compared the 3D-porosity of granule stacks obtained or prepared with nine biomaterials Osteopure® , Lubboc® , Bio-Oss® , CopiOs® , TCP Dental® , TCP Dental HP® , KeraOs® , and TCH® in comparison with that of human trabecular bone...
April 19, 2018: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/29658666/-application-of-modified-lateral-window-for-maxillary-sinus-floor-augmentation
#7
Wei Lu, Mengna Lin, Shifang Zhao, Huiming Wang, Fuming He
<b>Objective:</b> To evaluate the clinical efficacy of modified lateral window for maxillary sinus floor augmentation (MSFA). <b>Methods:</b> Fifty-five patients who visited the Stomatology Hospital Affiliated to Zhejiang University School of Medicine between June 2012 and October 2014 were enrolled in the study. Patients underwent MSFA with Bio-Oss grafts based on modified access window. During the operation the vertical height of the bony window was reduced from 6-8 mm of conventional oval window to 4-5 mm of slot-shaped window...
May 25, 2017: Zhejiang da Xue Xue Bao. Yi Xue Ban, Journal of Zhejiang University. Medical Sciences
https://www.readbyqxmd.com/read/29613862/comparative-histomorphometric-analysis-of-maxillary-sinus-augmentation-with-deproteinized-bovine-bone-and-demineralized-particulate-human-tooth-graft-an-experimental-study-in-rabbits
#8
Xiping Xu, Dong-Seok Sohn, Hyung-Gyun Kim, Sang-Jae Lee, Yong-Suk Moon
PURPOSE: The aim of this animal study is to evaluate, by histomorphometric analysis, new bone formation in rabbit maxillary sinuses with Bio-Oss and demineralized particulate human tooth graft. MATERIALS AND METHODS: Bilateral sinus augmentation procedures were performed in 8 adult male rabbits. After preparation of replaceable bony windows on the lateral wall of the nasal cavity with a piezoelectric surgical device, deproteinized bovine graft (Bio-Oss) was grafted in the new compartment of the maxillary sinus after elevation of the sinus membrane in the control group...
April 2, 2018: Implant Dentistry
https://www.readbyqxmd.com/read/29543926/gene-expression-and-microcomputed-tomography-analysis-of-grafted-bone-using-deproteinized-bovine-bone-and-freeze-dried-human-bone
#9
Thanyaporn Kangwannarongkul, Keskanya Subbalekha, Philaiporn Vivatbutsiri, Jaijam Suwanwela
PURPOSE: Bio-Oss and demineralized freeze-dried bone allograft (DFDBA) are two commercial bone grafts that have been associated with clinical success for many years. However, there are few in vivo studies regarding their healing mechanism. The purpose of this study was to investigate the level of bone formation using microcomputed tomography (micro-CT) and gene expression in mouse calvaria at 1 and 3 months after bone grafting with deproteinized bovine bone and freeze-dried human bone, and compare them to natural bone healing...
March 15, 2018: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/29513772/histologic-and-radiographic-analysis-of-nonhealing-extraction-sockets-treated-with-bio-oss-collagen-after-a-4-month-healing-period-a-prospective-descriptive-study-in-humans
#10
Federico Tirone, Stefano Salzano, Marco Pagano
Healing of extraction sockets may sometimes result in formation of fibrous tissue instead of bone, even after 4 months, an occurrence that may hinder implant placement. The aim of this preliminary observational study was to histologically evaluate quality and amount of bone regeneration after treating nonhealing sockets with a bovine-derived xenograft enriched with porcine collagen (Bio-Oss Collagen, Geistlich) without barrier membranes. Biopsy specimens were collected during implant placement, 4 months after grafting...
March 7, 2018: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/29508553/biocompatibility-and-osteoconductivity-of-plcl-coated-and-noncoated-xenografts-an-in-vitro-and-preclinical-trial
#11
Yaniv Mayer, Ofir Ginesin, Alaa Khutaba, Eli E Machtei, Hadar Zigdon Giladi
BACKGROUND: Cells, scaffolds, and growth factors are the key components in bone tissue engineering. Scaffold composition, topography, and architecture influence the amount of regenerated bone in the implantation site. The aims of the study were to compare viability and proliferation of mesenchymal stem cells (MSCs) seeded onto two commercial xenografts: Bio-Oss (BO) and bioactive bone bovine (BB). Next, these materials were compared for histomorphometric bone formation in a socket preservation model in rats...
March 6, 2018: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/29485462/new-bone-formation-process-using-bio-oss-and-collagen-membrane-for-rat-calvarial-bone-defect-histological-observation
#12
Shin Kasuya, Nahoko Kato-Kogoe, Michi Omori, Kayoko Yamamoto, Shogo Taguchi, Hiroshi Fujita, Naoko Imagawa, Akihiro Sunano, Kazuya Inoue, Yuichi Ito, Azumi Hirata, Takaaki Ueno, Peter K Moy
PURPOSE: We carried out guided bone regeneration of cranial bone defects in rats using the bovine bone substitute Bio-Oss and a collagen membrane and performed histological observations of the bone repair process. MATERIALS AND METHODS: Bone defects were created in the cranial bones of 30 15-week-old Sprague-Dawley rats. We made 3 groups. A is unfilled, B is Bio-Oss, and C is Bio-Oss plus a collagen membrane. At 4 or 8 weeks postoperatively, tissue samples were taken...
February 26, 2018: Implant Dentistry
https://www.readbyqxmd.com/read/29457935/customized-titanium-lattice-structure-in-three-dimensional-alveolar-defect-an-initial-case-letter
#13
Marcus Seiler, Peer W Kaemmerer, Michael Peetz, Amely Gundula Hartmann
The aim of this initial case report was to provide a new protocol for the clinical application of a patient-specific titanium lattice structure (Yxoss CBR®, ReOSS, Filderstadt, Germany) for customized bone regeneration. To obtain a 3-dimensional reconstruction of a posterior mandible segment in a 61-year-old woman, a patient-specific titanium customized lattice structure was used. As graft material autogenous bone tissue mixed with xenogenic alloplastic material (Bio Oss®, Geistlich Pharma, Wolhusen, Switzerland) was obtained for reconstruction...
February 19, 2018: Journal of Oral Implantology
https://www.readbyqxmd.com/read/29385747/hydrophilicity-viscoelastic-and-physicochemical-properties-variations-in-dental-bone-grafting-substitutes
#14
Branko Trajkovski, Matthias Jaunich, Wolf-Dieter Müller, Florian Beuer, Gregory-George Zafiropoulos, Alireza Houshmand
The indication-oriented Dental Bone Graft Substitutes (DBGS) selection, the correct bone defects classification, and appropriate treatment planning are very crucial for obtaining successful clinical results. However, hydrophilic, viscoelastic, and physicochemical properties' influence on the DBGS regenerative potential has poorly been studied. For that reason, we investigated the dimensional changes and molecular mobility by Dynamic Mechanical Analysis (DMA) of xenograft (cerabone® ), synthetic (maxresorb® ), and allograft (maxgraft® , Puros® ) blocks in a wet and dry state...
January 30, 2018: Materials
https://www.readbyqxmd.com/read/29377475/preservation-and-augmentation-of-molar-extraction-sites-affected-by-severe-bone-defect-due-to-advanced-periodontitis-a-prospective-clinical-trial
#15
Liping Zhao, Tao Xu, Wenjie Hu, Kwok-Hung Chung
BACKGROUND: Studies of the extracted infected-molar ridge preservation are limited. PURPOSE: To compare alterations of hard and soft tissue in infected-molar sockets receiving ridge preservation compared with natural healing. MATERIALS AND METHODS: Thirty-five infected-molar extraction sites either preserving with Bio-Gide membrane covered the Bio-Oss material or receiving natural healing procedure as controls. The soft tissue profile was evaluated before tooth extraction and after 6-month healing...
January 29, 2018: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/29355856/bone-graft-and-substitutes-associated-with-titanium-dome-for-vertical-bone-formation-in-osseointegrated-implants-histomorphometric-analysis-in-dogs
#16
Mario Vinicius Zendron, Matheus Völz Cardoso, Giovana Fuzeto Veronesi, Daniel Romeu Benchimol de Resende, Carla Andreotti Damante, Adriana Campos Passanezi Sant'ana, Sebastião Luis Aguiar Greghi, Mariana Schutzer Ragghianti Zangrando
PURPOSE: This animal study investigated vertical bone formation (VBF) around implants and used histomorphometric analysis to compare different bone-filling materials associated with a massive titanium dome as a tissue barrier. MATERIALS AND METHODS: Seven dogs were submitted to surgical procedures with extraoral access to the lower edge of the mandible, and four implants were semi-inserted in each animal. Each implant received one treatment: autogenous bone with clot (AB), control clot (C), synthetic graft (Biogran [BG]), or xenograft (Bio-Oss [BO])...
March 2018: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/29302589/evaluation-of-bone-healing-using-rhbmp-2-soaked-hydroxyapatite-in-ridge-augmentation-a-prospective-observational-study
#17
Hyun-Suk Kim, Ju-Cheol Park, Pil-Young Yun, Young-Kyun Kim
Background: The goal of this study is to evaluate complication and effectiveness of alveolar ridge augmentations using a hydroxyapatite-based alloplastic bony substitute with rhBMP-2. Methods: A total of 10 patients (4 males, 6 females; 58.5 ± 8.6 years) participated in this clinical research. Alveolar ridge augmentations were performed in edentulous (4 maxillary posterior, 5 mandibular posterior, and 1 mandibular anterior) regions. Anorganic bovine bone (ABB; Bio-Oss®, Geistlich Pharma AG, Wolhusen, Switzerland) was used as the bone graft material in the control group ( n  = 5)) while hydroxyapatite-based alloplastic bony substitute with rhBMP-2(HA+rhBMP-2; NOVOSIS®-Dent, CGBio Inc...
December 2017: Maxillofacial Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29240203/scar-tissue-formation-following-alveolar-ridge-preservation-a-case-control-study
#18
Stefan Fickl, Frederic Kauffmann, Christian F Stappert, Anke Kauffmann, Ulrich Schlagenhauf
The aim of this retrospective case control study was to compare a porcine collagen matrix (Mucograft Seal, Geistlich) with a free gingival punch graft with respect to size, invagination, and color of resulting soft tissue scar formation. Following definition of inclusion and exclusion criteria, 22 patients were retrospectively included in this study. The patients were divided into two groups. In group A, the extraction socket was filled with bovine bone mineral (Bio-Oss, Geistlich) and covered with a free gingival punch graft...
January 2018: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/29181458/minimally-invasive-crestal-sinus-lift-technique-and-simultaneous-implant-placement
#19
Xian Zhou, Xiu Lian Hu, Jian Hui Li, Ye Lin
OBJECTIVE: To evaluate the effectiveness and clinical results of a new crestal sinus lift technique used to elevate the sinus floor simultaneously with bone grafts and implant placement. METHODS: Eleven patients underwent this crestal sinus lift technique performed using an SCA KIT. The mean residual bone height was 6.4 mm (range: 4.1 mm to 8.6 mm). Bio-Oss collagen was used as the graft material, and 12 implants were simultaneously placed after sinus augmentation...
2017: Chinese Journal of Dental Research
https://www.readbyqxmd.com/read/29154676/effects-of-bone-regeneration-materials-and-tooth-movement-timing-on-canine-experimental-orthodontic-treatment
#20
Ferdinand Mabula Machibya, Yiyuan Zhuang, Weizhong Guo, Dongdong You, Shan Lin, Dong Wu, Jiang Chen
OBJECTIVES: To evaluate the effects of bone regeneration materials and orthodontic tooth movement (OTM) timing on tooth movement through alveolar bone defects treated with guided bone regeneration (GBR) utilizing xenografts (Bio-Oss) and alloplast (β-TCP). MATERIALS AND METHODS: Twenty-four standard alveolar bone defects in six male beagle dogs were treated by GBR using either Bio-Oss or β-TCP (experimental), whereas the control defects were left empty. The defects were further grouped into early or late subgroups, depending on OTM timing after GBR (ie 1 month or 2 months, respectively)...
March 2018: Angle Orthodontist
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