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https://www.readbyqxmd.com/read/28203026/-histomorphometric-evaluation-of-ridge-preservation-after-molar-tooth-extraction
#1
Y L Zhan, W J Hu, T Xu, M Zhen, R F Lu
OBJECTIVE: To evaluate bone formation in human extraction sockets with absorbed surrounding walls augmented with Bio-Oss and Bio-Gide after a 6-month healing period by histologic and histomorphometric analyses. METHODS: Six fresh molar tooth extraction sockets in 6 patients who required periodontally compromised moral tooth extraction were included in this study. The six fresh extraction sockets were grafted with Bio-Oss particle covered with Bio-Gide. The 2.8 mm×6...
February 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28186709/in-vitro-evaluation-of-the-biological-compatibility-and-antibacterial-activity-of-a-bone-substitute-material-consisting-of-silver-doped-hydroxyapatite-and-bio-oss-%C3%A2
#2
Jingjue Gong, Lei Yang, Qi He, Ting Jiao
This study evaluated biological compatibility and antibacterial activity of a bone substitute material consisting of silver-doped hydroxyapatite (AgHA) and Bio-Oss(®) with different mixture ratios in vitro and investigated its antibacterial mechanism. AgHA was synthesized by a chemical precipitation method. After characterization, AgHA was mixed with Bio-Oss(®) at three ratios: 1:1, 1:2, and 1:4 by weight. Then, Porphyromonas gingivalis (Pg) and Fusobacterium nucleatum (Fn) were used to test the antibacterial activity of the mixture...
February 10, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28027692/comparison-of-3d-printed-poly-%C3%A9-caprolactone-scaffolds-functionalized-with-tricalcium-phosphate-hydroxyapatite-bio-oss-or-decellularized-bone-matrix
#3
Ethan Nyberg, Alexandra Rindone, Amir Dorafshar, Warren L Grayson
Three-dimensional (3D)-printing facilitates rapid, custom manufacturing of bone scaffolds with a wide range of material choices. Recent studies have demonstrated the potential for 3D-printing bioactive (i.e., osteo-inductive) scaffolds for use in bone regeneration applications. In this study, we 3D-printed porous poly-ɛ-caprolactone (PCL) scaffolds using a fused deposition modeling (FDM) process and functionalized them with mineral additives that have been widely used commercially and clinically: tricalcium phosphate (TCP), hydroxyapatite (HA), Bio-Oss (BO), or decellularized bone matrix (DCB)...
February 7, 2017: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/27987520/-dental-implantation-and-soft-tissue-augmentation-after-ridge-preservation-in-a-molar-site-a-case-report
#4
L P Zhao, Y L Zhan, W J Hu, H J Wang, Y P Wei, M Zhen, T Xu, Y S Liu
For ideal implant rehabilitation, an adequate bone volume, optical implant position, and stable and healthy soft tissue are required. The reduction of alveolar bone and changes in its morphology subsequent to tooth extraction will result in insufficient amount of bone and adversely affect the ability to optimally place dental implants in edentulous sites. Preservation of alveolar bone volume through ridge preservation has been demonstrated to reduce the vertical and horizontal contraction of the alveolar bone crest after tooth extraction and reduce the need for additional bone augmentation procedures during implant placement...
December 18, 2016: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/27934787/long-term-biological-performance-of-injectable-and-degradable-calcium-phosphate-cement
#5
Eline-Claire Grosfeld, Jan Willem M Hoekstra, Ralf-Peter Herber, Dietmar J O Ulrich, John A Jansen, Jeroen J J P van den Beucken
Enhancing degradation of poorly degrading injectable calcium phosphate (CaP) cements (CPCs) can be achieved by adding poly(lactic-co-glycolic acid) (PLGA) microparticles, generating porosity after polymer degradation. CPC-PLGA has proven to be biodegradable, although its long-term biological performance is still unknown. Optimization of injectability could be achieved via addition of carboxymethyl cellulose (CMC). Here, we evaluated the long-term in vivo performance of CPC-PLGA with or without the lubricant CMC in comparison to the devitalized bovine bone mineral (DBBM) predicate device Bio-Oss(®)...
December 9, 2016: Biomedical Materials
https://www.readbyqxmd.com/read/27889939/the-performance-of-cpc-plga-and-bio-oss-%C3%A2-for-bone-regeneration-in-healthy-and-osteoporotic-rats
#6
Claire I A van Houdt, Dietmar J O Ulrich, John A Jansen, Jeroen J J P van den Beucken
The current study aimed to evaluate the biological performance of calcium phosphate cement (CPC) with polylactic-co-glycolic acid (PLGA) micro-particles and Bio-Oss(®) in ovariectomized and healthy rats. Thirty-two Wistar rats received alternating experimental CPC/PLGA and Bio-Oss(®) in femoral condyle defects in both femurs 6 weeks after ovariectomy (OVX, n = 16) or sham operation (SHAM, n = 16). Six weeks after OVX or SHAM surgery, bone morphology was analyzed by in vivo computed tomography (CT) to confirm osteoporotic bone condition...
November 27, 2016: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/27857771/a-histologic-histomorphometric-and-radiographic-comparison-between-two-complexes-of-cenoboen-cenomembrane-and-bio-oss-bio-gide-in-lateral-ridge-augmentation-a-clinical-trial
#7
Babak Amoian, Ehsan Moudi, Maryam Seyed Majidi, S M Ali Tabatabaei
BACKGROUND: Several grafting materials have been used for alveolar ridge augmentation. The literature lacks researches to compare CenoBone to other grafting materials. The aim of this study was to compare CenoBone/CenoMembrane complex to Bio-Oss/Bio-Gide complex in lateral alveolar bone augmentation in terms of radiographic, histologic, and histomorphometric parameters. MATERIALS AND METHODS: In this randomized controlled trial, ten patients who needed lateral ridge augmentation were selected and augmentations were done using either of CenoBone/CenoMembrane or Bio-Oss/Bio-Gide complexes...
September 2016: Dental Research Journal
https://www.readbyqxmd.com/read/27815999/bone-regeneration-induced-by-a-3d-architectured-hydrogel-in-a-rat-critical-size-calvarial-defect
#8
P Lohmann, A Willuweit, A T Neffe, S Geisler, T P Gebauer, S Beer, H H Coenen, H Fischer, B Hermanns-Sachweh, A Lendlein, N J Shah, F Kiessling, K-J Langen
Bone regeneration can be stimulated by implantation of biomaterials, which is especially important for larger bone defects. Here, healing potency of the porous ArcGel was evaluated in a critical-size calvarial bone defect in rats in comparison with clinical standard autologous bone and Bio-Oss(®) Collagen (BioOss), a bone graft material frequently used in clinics. Bone healing and metabolic processes involved were monitored longitudinally by [(18)F]-fluoride and [(18)F]-FDG μ-PET/CT 1d, 3d, 3w, 6w, and 12w post implantation...
October 28, 2016: Biomaterials
https://www.readbyqxmd.com/read/27747635/immediate-placement-and-provisionalization-of-an-implant-after-removal-of-an-impacted-maxillary-canine-two-case-reports
#9
Elise G Zuiderveld, Henny J A Meijer, Arjan Vissink, Gerry M Raghoebar
Single immediate implant replacement is accompanied by excellent survival rates and a favorable esthetic outcome. The objective of this report was to describe a surgical approach for removal of a buccal or palatally located impacted secondary canine, combined with extraction of the failing primary canine, and immediate placement and provisionalization of an implant. A window technique was applied for surgical removal of the impacted canine. The alveolar crest was preserved. After extraction of the primary canine, the implant was inserted with primary stability...
December 2015: International Journal of Implant Dentistry
https://www.readbyqxmd.com/read/27704640/vertical-augmentation-of-the-posterior-atrophic-mandible-by-interpositional-grafts-in-a-split-mouth-design-a-human-tomography-evaluation-pilot-study
#10
Eduardo Pinheiro Domingues, Rafael Fernandes Ribeiro, Martinho Campolina Rebello Horta, Flávio Ricardo Manzi, Maurício Greco Côsso, Elton Gonçalves Zenóbio
OBJECTIVE: Using computed tomography, to compare vertical and volumetric bone augmentation after interposition grafting with bovine bone mineral matrix (GEISTLICH BIO-OSS(®) ) or hydroxyapatite/tricalcium phosphate (STRAUMANN(®) BONECERAMIC) for atrophic posterior mandible reconstruction through segmental osteotomy. MATERIAL AND METHODS: Seven patients received interposition grafts in the posterior mandible for implant rehabilitation. The computed tomography cone beam images were analysed with OsiriX Imaging Software 6...
October 4, 2016: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/27692642/implant-stability-after-sinus-floor-augmentation-with-deproteinized-bovine-bone-mineral-particles-of-different-sizes-a-prospective-randomized-and-controlled-split-mouth-clinical-trial
#11
T L M R Dos Anjos, R S de Molon, P R F Paim, E Marcantonio, E Marcantonio, R S Faeda
The aim of this study was to compare implant stability after maxillary sinus floor augmentation using small- or large-sized particles of Bio-Oss. Ten partially edentulous patients requiring bilateral maxillary sinus floor augmentation were enrolled. The subjects were assigned randomly to one of two experimental groups: maxillary sinus was filled with 0.25-1mm particle size (small particles) and the contralateral side was filled with 1-2mm particle size (large particles). After 8 months, a total of 25 implants were placed in the two maxillary sinuses...
December 2016: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27682609/a-comparative-study-of-the-effect-of-bio-oss-in-combination-with-concentrated-growth-factors-or-bone-marrow-derived-mesenchymal-stem-cells-in-canine-sinus-grafting
#12
Fang Wang, Qiong Li, Zuolin Wang
BACKGROUND: To compare the effects of Bio-Oss in combination with concentrated growth factors (CGFs) and bone marrow-derived mesenchymal stem cells (BMSCs) on bone regeneration for maxillary sinus floor augmentation in beagle dogs. METHODS: Six beagle dogs received bilateral maxillary sinus floor augmentation. Venous blood drawn from dogs was collected and centrifugated to obtain CGFs. BMSCs derived from canine bone marrow was cultured using density gradient centrifugation...
September 28, 2016: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/27680032/characterization-and-angiogenic-potential-of-xenogeneic-bone-grafting-materials-role-of-periodontal-ligament-cells
#13
Charlotte Rombouts, Charlotte Jeanneau, Josette Camilleri, Patrick Laurent, Imad About
Adequate revascularization is a prerequisite for successful healing of periodontal bone defects. This study characterized three different xenogeneic bone grafting materials: Gen-Os of equine and porcine origins, and anorganic Bio-Oss. We also investigated their angiogenic potential. All materials were composed of poorly crystalline calcium oxide phosphate, with Bio-Oss exhibiting a carbonated phase and larger particle size and both Gen-Os showing the presence of collagen. Both Gen-Os materials significantly enhanced vascular endothelial growth factor (VEGF) secretion by PDL cells...
December 1, 2016: Dental Materials Journal
https://www.readbyqxmd.com/read/27623790/the-influence-of-the-sensory-neurotransmitter-calcitonin-gene-related-peptide-on-bone-marrow-mesenchymal-stem-cells-from-ovariectomized-rats
#14
Jie Chen, Ge Ma, Wei Liu, Yanpu Liu, Yuxiang Ding
In order to explore the effects of calcitonin gene-related peptide (CGRP) on bone mesenchymal stem cells (BMSCs) from ovariectomized (OVX) rats, an OVX rat model was used. An ELISA was performed to examine the changes in CGRP level in the plasma and skeleton. The BMSCs from the sham rats were designated group A. The BMSCs from the OVX rats (groups B, C, D and E) were treated with different concentrations of CGRP (10(-6), 10(-8), 10(-10) and 0 M) in vitro. The proliferation and osteogenic and adipogenic differentiation potential of the BMSCs were evaluated...
September 13, 2016: Journal of Bone and Mineral Metabolism
https://www.readbyqxmd.com/read/27618613/microarchitecture-and-biomechanical-evaluation-of-boneceramic-grafted-alveolar-defects-during-tooth-movement-in-rat
#15
Nan Ru, Sean Shih-Yao Liu, Yuxing Bai, Song Li, Yunfeng Liu, Guanjun Zhou
OBJECTIVE:   BoneCeramic can regenerate bone in alveolar defects, but it remains unknown whether it is feasible to move a tooth through BoneCeramic grafting sites. The objective of this study was to investigate three-dimensional real-time bone responses and micromechanical properties in the grafting sites during orthodontic tooth movement. METHODS:   Sixty 5-week-old rats were randomly assigned into three groups to receive BoneCeramic, natural bovine cancellous bone particles (Bio-Oss), and no graft, respectively, after the extraction of the left maxillary first molar...
September 12, 2016: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/27609392/-clinical-study-of-titanium-mesh-in-conjunction-with-concentrate-growth-factors-to-rebuild-severe-bone-defect-of-anterior-maxilla
#16
Hai-Yan Lin, Wei-Dan Zhang, Yan-Chun Yu, Hong-Yu Jia, Ren-Fei Wang
PURPOSE: To evaluate the effect of overlaying titanium mesh with concentrate growth factors(CGF) for rebuilding severe buccal bone defect of anterior maxilla when used in association with dental implantation. METHODS: Twenty patients with severe buccal bone defect of maxilla were selected. A total of 25 dental implants were placed, including 5 cases in bilateral central incisor area and 15 cases in unilateral central incisor area. After implantation, the defects were treated with Bio-oss and Bio-guid in conjunction with fixation of titanium mesh and then CGF technology was used...
June 2016: Shanghai Kou Qiang Yi Xue, Shanghai Journal of Stomatology
https://www.readbyqxmd.com/read/27576064/in-vivo-micro-computed-tomography-evaluation-of-boneceramic-grafted-alveolar-defects-during-orthodontic-tooth-movement
#17
Nan Ru, Sean Shih-Yao Liu, Yuxing Bai, Song Li, Yunfeng Liu, Guanjun Zhou
OBJECTIVE: To investigate three-dimensional microarchitecture and micromechanical properties of alveolar bone in the BoneCeramic grafting sites during orthodontic tooth movement. MATERIALS AND METHODS: Sixty 5-week-old rats were randomly assigned into three groups to receive BoneCeramic, natural bovine cancellous bone particles (Bio-Oss), and no graft, respectively, after the extraction of the left maxillary first molar. After 4 weeks, the maxillary left second molar was moved into the extraction site for 28 days...
August 30, 2016: Angle Orthodontist
https://www.readbyqxmd.com/read/27546095/evaluation-of-peri-implant-crevicular-fluid-prostaglandin-e2-levels-in-augmented-extraction-sockets-by-different-biomaterials
#18
RANDOMIZED CONTROLLED TRIAL
Eylem Ayhan Alkan, Gülay Tüter, Ateş Parlar, Ayşegül Yücel, Bülent Kurtiş
OBJECTIVES: This study compares peri-implant crevicular fluid (PICF) prostaglandin E2 (PGE2) levels, clinical parameters and implant stability quotient (ISQ) values around implants placed in augmented extraction sockets. MATERIALS AND METHODS: The sockets (24 in total) were randomly augmented using either EMD or Bio-Oss Collagen. Implant placements were performed after three months of healing. ISQ readings were evaluated at three points: at the time of surgery, at the first month and at the third month...
October 2016: Acta Odontologica Scandinavica
https://www.readbyqxmd.com/read/27441185/effect-of-hydroxyapatite-on-critical-sized-defect
#19
Ryoe-Woon Kim, Ji-Hyoung Kim, Seong-Yong Moon
BACKGROUND: Xenologous or synthetic graft materials are commonly used as an alternative for autografts for guided bone regeneration. The purpose of this study was to evaluate effectiveness of carbonate apatite on the critical-size bone defect of rat's calvarium. METHODS: Thirty-six critical-size defects were created on 18 adult male Sprague-Dawley rat calvaria under general anesthesia. Calvarial bones were grinded with 8 mm in daimeter bilaterally and then filled with (1) no grafts (control, n = 10 defects), (2) bovine bone mineral (Bio-Oss®, Geistlich Pharma Ag...
December 2016: Maxillofacial Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/27414994/bone-grafting-with-granular-biomaterial-in-segmental-maxillary-osteotomy-a-case-report
#20
Orion Luiz Haas Junior, Lucas da Silva Meirelles, Neimar Scolari, Otávio Emmel Becker, Marcelo Fernandes Santos Melo, Rogério Belle de Oliveira
INTRODUCTION: Segmental maxillary osteotomy enables correction of anterior open bites. However, the outcome can be somewhat unstable, particularly if pseudarthrosis occurs. Bone grafts can be used to prevent this complication. Among the many biomaterials available for grafting, Bio-oss(®) has been used successfully in a range of modalities, with studies to support several indications. This report describes a case of segmental maxillary osteotomy in which Bio-oss(®) granules were used as bone grafts in the surgical gap...
2016: International Journal of Surgery Case Reports
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