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https://www.readbyqxmd.com/read/29154676/effects-of-bone-regeneration-materials-and-tooth-movement-timing-on-canine-experimental-orthodontic-treatment
#1
Ferdinand Mabula Machibya, Yiyuan Zhuang, Weizhong Guo, Dongdong You, Shan Lin, Dong Wu, Jiang Chen
OBJECTIVES: To evaluate the effects of bone regeneration materials and orthodontic tooth movement (OTM) timing on tooth movement through alveolar bone defects treated with guided bone regeneration (GBR) utilizing xenografts (Bio-Oss) and alloplast (β-TCP). MATERIALS AND METHODS: Twenty-four standard alveolar bone defects in six male beagle dogs were treated by GBR using either Bio-Oss or β-TCP (experimental), whereas the control defects were left empty. The defects were further grouped into early or late subgroups, depending on OTM timing after GBR (ie 1 month or 2 months, respectively)...
November 20, 2017: Angle Orthodontist
https://www.readbyqxmd.com/read/29147713/variation-of-the-bone-forming-ability-with-the-physicochemical-properties-of-calcium-phosphate-bone-substitutes
#2
Rongquan Duan, Davide Barbieri, Xiaoman Luo, Jie Weng, Chongyun Bao, Joost D de Bruijn, Huipin Yuan
Because of their bioactive properties and chemical similarity to the inorganic component of bone, calcium phosphate (CaP) materials are widely used for bone regeneration. Six commercially available CaP bone substitutes (Bio-Oss, Actifuse, Bi-Ostetic, MBCP, Vitoss and chronOs) as well as two tricalcium phosphate (TCP) ceramics with either a micron-scale (TCP-B) or submicron-scale (TCP-S) surface structure are characterized and their bone forming potential is evaluated in a canine ectopic implantation model. After 12 weeks of implantation in the paraspinal muscle of four beagles, sporadic bone (0...
November 17, 2017: Biomaterials Science
https://www.readbyqxmd.com/read/29100829/prospective-and-randomized-evaluation-of-chronos-and-bio-oss-in-human-maxillary-sinuses-histomorphometric-and-immunohistochemical-assignment-for-runx-2-vascular-endothelial-growth-factor-and-osteocalcin
#3
João Paulo Bonardi, Rodrigo Dos Santos Pereira, Fernanda Brasil Jorge Daura Boos, Leonarod Perez Faverani, Geraldo Luiz Griza, Roberta Okamoto, Eduardo Hochuli-Vieira
PURPOSE: The aim of this study was to compare ChronOS (β-tricalcium phosphate), Bio-Oss, and their addition to an autogenous bone graft in a 1:1 ratio in human maxillary sinus bone augmentation. MATERIALS AND METHODS: Thirty maxillary sinuses were divided in 5 groups: group 1 included 6 maxillary sinuses grafted with autogenous bone graft alone; group 2 included 6 maxillary sinuses grafted with ChronOS; group 3 included 6 maxillary sinuses grafted with ChronOS and autogenous bone graft in a 1:1 ratio; group 4 included 6 maxillary sinuses grafted with Bio-Oss; and group 5 included 6 maxillary sinuses grafted with Bio-Oss and autogenous bone graft in a 1:1 ratio...
October 10, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29091020/do-clinical-and-radiological-assessments-contribute-to-the-understanding-of-biomaterials-results-from-a-prospective-randomized-sinus-augmentation-split-mouth-trial
#4
Jonas Lorenz, Tadas Korzinskas, Poju Chia, Sarah Al Maawi, Katrin Eichler, Robert Sader, Shahram Ghanaati
The present prospective randomized split-mouth trial reports on the 3-year clinical and radiological follow-up investigation of implants placed 7 months after sinus augmentation with two different bone substitute materials. Aim of the study was to complete the histologic observation of the cellular reactions by analysis of the implants and the volumetric changes of the augmented bone substitute materials. A sinus augmentation split-mouth trial was performed in 14 patients with the synthetic bone substitute material Nanobone® (NB) and the xenogeneic Bio-Oss® (BO)...
November 1, 2017: Journal of Oral Implantology
https://www.readbyqxmd.com/read/29082254/sodium-dna-for-bone-tissue-regeneration-an-experimental-study-in-rat-calvaria
#5
Barbara Buffoli, Gaia Favero, Elisa Borsani, Ramon Boninsegna, Guido Sancassani, Mauro Labanca, Rita Rezzani, Pier Francesco Nocini, Massimo Albanese, Luigi Fabrizio Rodella
Surgical techniques in dental and maxillofacial surgery request fast bone tissue regeneration, so there is a significant need to improve therapy for bone regeneration. Several studies have recently underlined the importance of nucleotides and nucleosides to increase cell proliferation and activity; in particular, the ability of polydeoxyribonucleotide (PDRN) to induce growth and activity of human osteoblasts was demonstrated. Sodium-DNA is the deoxyribonucleic acid (DNA) extracted from the gonadic tissue of male sturgeon and then purified, depolymerized, and neutralized with sodium hydroxide...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29080268/histomorphometric-analyses-of-area-fraction-of-different-ratios-of-bio-oss-%C3%A2-and-bone-prior-to-grafting-procedures-an-in-vitro-study-to-demonstrate-a-baseline
#6
Hanna Aludden, Anna Dahlin, Thomas Starch-Jensen, Christer Dahlin, Arne Mordenfeld
OBJECTIVE: The objective of this study was to estimate the area fraction of different ratios of Bio-Oss(®) and bone, prior to grafting in an in vitro model to demonstrate a histomorphometric baseline. METHODS: Bio-Oss(®) particles were mixed with autogenous bone from pig jaw in three different ratios (50:50, 80:20 and 100:0) and packed in rice paper in a standardized procedure. Histomorphometric analyses were performed in 25 specimens and 74 regions of interest...
October 27, 2017: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/29075416/secondary-implant-stability-outcome-of-immediate-versus-late-placed-variable-thread-implants-in-the-maxilla-a-retrospective-cohort-study
#7
Nicolas Grognard, Gino Verleye, Dimitrios Mavreas, Bart Vande-Vannet
BACKGROUND: The healing of xenograft augmentated intra-alveolar gaps following immediate implant placement (IMIP) after tooth extraction is likely to differ in time and density compared to the native bone part that directly contacts the implant. MATERIAL AND METHODS: Secondary implant stability (SIS) data recorded 2-3 months following a late implant placement protocol (LIP) (n= 43) and 6-8 months following an immediate implant placement protocol (IMIP) (n=33) of variable-thread implants (Nobel Active™) in the maxilla were retrospectively collected from files of 63 patients (42 females, 21 males)...
September 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/29067095/bio-oss-%C3%A2-modified-by-calcitonin-gene-related-peptide-promotes-osteogenesis-in-vitro
#8
Yuanjing Li, Lan Yang, Zhichao Zheng, Zhengmao Li, Tian Deng, Wen Ren, Caijuan Wu, Lvhua Guo
Bio-Oss(®) and α-calcitonin gene-related peptide (CGRP) are involved in osteogenesis. However, it has remained to be assessed how α-CGRP affects the effect of Bio-Oss. In the present study, primary osteoblasts were incubated with α-CGRP, Bio-Oss, α-GGRP-Bio-Oss or mimic-α-CGRP. The proliferation rate, mineralization nodules, alkaline phosphatase (ALP) activity and the expression of osteogenic genes were measured by a Cell Counting Kit-8 assay, Alizarin Red-S staining, ALP activity detection and reverse-transcription quantitative PCR as well as western blot analysis, respectively...
November 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29064533/in-vitro-effects-of-particulate-bone-substitute-materials-on-the-resorption-activity-of-human-osteoclasts
#9
G Russmueller, L Winkler, R Lieber, R Seemann, K Pirklbauer, C Perisanidis, B Kapeller, E Spassova, E Halwax, W P Poeschl, K Macfelda, D Moser
Much research has been done on bone cells, but only a few studies deal with biomaterial-induced effects on human osteoclasts, which may take on an important role in the successful regeneration of bone. In order to highlight such effects, human peripheral blood mononuclear cells (PBMCs) were extracted from venous blood, differentiated to osteoclasts and then cultured in, the presence of five particulate hydroxyapatite (HA)/β-tricalcium phosphate (TCP) biomaterials, on bovine bone slices and glass cover slips...
October 24, 2017: European Cells & Materials
https://www.readbyqxmd.com/read/29021982/autologous-periosteum-derived-micrografts-and-plga-ha-enhance-the-bone-formation-in-sinus-lift-augmentation
#10
Ruggero Rodriguez Y Baena, Riccardo D'Aquino, Antonio Graziano, Letizia Trovato, Antonio C Aloise, Gabriele Ceccarelli, Gabriella Cusella, André A Pelegrine, Saturnino M Lupi
Sinus lift augmentation is a procedure required for the placement of a dental implant, whose success can be limited by the quantity or quality of available bone. To this purpose, the first aim of the current study was to evaluate the ability of autologous periosteum-derived micrografts and Poly(lactic-co-glycolic acid) (PLGA) supplemented with hydroxyl apatite (HA) to induce bone augmentation in the sinus lift procedure. Secondly, we compared the micrograft's behavior with respect to biomaterial alone, including Bio-Oss® and PLGA/HA, commercially named Alos...
2017: Frontiers in Cell and Developmental Biology
https://www.readbyqxmd.com/read/28868669/attributes-of-bio-oss-%C3%A2-and-moa-bone-%C3%A2-graft-materials-in-a-pilot-study-using-the-sheep-maxillary-sinus-model
#11
M M Smith, W J Duncan, D E Coates
BACKGROUND AND OBJECTIVE: The aim of this pilot study was to characterize surface morphology and to evaluate resorption and osseous healing of two deproteinated bovine bone graft materials after sinus grafting in a large animal model. MATERIAL AND METHODS: Surfaces of a novel particulate bovine bone graft, Moa-Bone(®) were compared with Bio-Oss(®) using scanning electron microscopy. Six sheep then had maxillary sinus grafting bilaterally, covered with BioGide(®) ...
September 4, 2017: Journal of Periodontal Research
https://www.readbyqxmd.com/read/28774818/the-protective-effect-of-platelet-released-growth-factors-and-bone-augmentation-bio-oss-%C3%A2-on-ethanol-impaired-osteoblasts
#12
Tolga Taha Sönmez, Andreas Bayer, Tillman Cremer, Jennifer Vanessa Phi Hock, Bernd Lethaus, Nisreen Kweider, Christoph Jan Wruck, Wolf Drescher, Holger Jahr, Sebastian Lippross, Thomas Pufe, Mersedeh Tohidnezhad
BACKGROUND: Chronic alcohol consumption is a known limiting factor for bone healing. One promising strategy to improve bone augmentation techniques with Bio-Oss(®) in oral and maxillofacial surgery might be the supportive application of platelet-concentrated biomaterials as platelet-released growth factor (PRGF). To address this matter, we performed an in vitro study investigating the protective effects of PRGF and Bio-Oss(®) in ethanol (EtOH) treated osteoblasts. METHODS: The SAOS-2 osteosarcoma cell line, with and without EtOH pretreatment was used...
July 31, 2017: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://www.readbyqxmd.com/read/28757934/applications-of-biomaterials-for-bone-augmentation-of-jaws-clinical-outcomes-and-in-vitro-studies
#13
L Tettamanti, M Andreasi Bassi, G Trapella, V Candotto, A Tagliabue
Partially or totally edentulous jaws frequently undergoes from moderate to severe bone atrophy with problems of prosthetic rehabilitation. The inability to make a prosthetic rehabilitation on implants may led to the use of a partial or total removable denture with difficulties in eating and speech, ulcerations of the oral mucosa and loss of facial vertical dimension. These problems may be solved performing bone augmentation procedures. Bone grafts and distraction osteogenesis brought implant dentistry from an experimental practice to become a consolidate dental procedure...
January 2017: Oral & Implantology
https://www.readbyqxmd.com/read/28732677/assessment-of-bone-repair-in-critical-size-defect-in-the-calvarium-of-rats-after-the-implantation-of-tricalcium-phosphate-beta-%C3%AE-tcp
#14
Leonardo de Freitas Silva, Erik Neiva Ribeiro de Carvalho Reis, Tânia Aparecida Barbara, João Paulo Bonardi, Idelmo Rangel Garcia, Paulo Sérgio Perri de Carvalho, Daniela Ponzoni
OBJECTIVES: Evaluating the osteoconductive property of tricalcium phosphate beta (β-TCP) in comparison to that of inorganic bovine bone for repair in a critical-size defect in the rat calvarium. MATERIALS AND METHODS: Critical-size defects of 7mm were made with a trephine in the calvaria of 48 Wistar rats. The animals were divided into four groups, and the defects in each group were filled with tricalcium phosphate beta (β-TCP), inorganic bovine bone (Bio-Oss), autogenous bone, or left empty...
July 18, 2017: Acta Histochemica
https://www.readbyqxmd.com/read/28731486/demineralized-dentin-and-enamel-matrices-as-suitable-substrates-for-bone-regeneration
#15
Nina Bono, Paolo Tarsini, Gabriele Candiani
BACKGROUND: In recent decades, tooth derivatives such as dentin (D) and enamel (E) have been considered as potential graft biomaterials to treat bone defects. This study aimed to investigate the effects of demineralization on the physical-chemical and biological behavior of D and E. METHODS: Human D and E were minced into particles (Ø<1 mm), demineralized and sterilized. Thorough physical-chemical and biochemical characterizations of native and demineralized materials were performed by SEM and EDS analysis and ELISA kits to determine mineral, collagen type I and BMP-2 contents...
July 20, 2017: Journal of Applied Biomaterials & Functional Materials
https://www.readbyqxmd.com/read/28655570/new-nano-hydroxyapatite-in-bone-defect-regeneration-a-histological-study-in-rats
#16
Paweł Kubasiewicz-Ross, Jakub Hadzik, Julia Seeliger, Karol Kozak, Kamil Jurczyszyn, Hanna Gerber, Marzena Dominiak, Christiane Kunert-Keil
Many types of bone substitute materials are available on the market. Researchers are refining new bone substitutes to make them comparable to autologous grafting materials in treatment of bone defects. The purpose of the study was to evaluate the osseoconductive potential and bone defect regeneration in rat calvaria bone defects treated with new synthetic nano-hydroxyapatite. The study was performed on 30 rats divided into 5 equal groups. New preproduction of experimental nano-hydroxyapatite material by NanoSynHap (Poznań, Poland) was tested and compared with commercially available materials...
September 2017: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://www.readbyqxmd.com/read/28613059/-experimental-study-of-transforming-growth-factor-%C3%AE-3-combined-with-dental-pulp-stem-cells-in-promoting-the-implant-s-osseointegration
#17
T Wang, Huojia Muhetaer, J Li
Objective: To investigate the effect of transforming growth factor-β3 (TGF-β3) and dental pulp stem cells (DPSC) in promoting the implant's osteointegration. Methods: Thirty-three New Zealand white rabbits were randomly divided into phosphate buffer saline (PBS) group, DPSC group and TGF-β3 + DPSC group (12 rabbits/group). Two teeth from the rabbits's mandibular incisors or molars were pulled out randomly, then implant were placed in the tooth extraction site immediately. In PBS group, the implant area was filled with Bio-Oss powder 0...
June 9, 2017: Zhonghua Kou Qiang Yi Xue za Zhi, Zhonghua Kouqiang Yixue Zazhi, Chinese Journal of Stomatology
https://www.readbyqxmd.com/read/28609508/evaluation-of-the-bone-regenerating-effects-of-two-anorganic-bovine-bone-grafts-in-a-critical-sized-alveolar-ridge-defect-model
#18
David M Kim, Heather Hong, Jerry Ching-Yi Lin, Myron Nevins
A preclinical trial was conducted to treat 54 mandibular critical-sized alveolar ridge defects in 27 canines. Each hemimandible was randomized to be treated with two different anorganic bovine bone grafts (group A = InterOss [SigmaGraft]; group B = Bio-Oss [Geistlich]) or negative control (group C = empty defect) followed by a 4-, 8-, or 12-week observation period. Microcomputed tomography, histology, histopathology, and histomorphometric analyses were performed to evaluate the safety and efficacy of these treatments...
July 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/28609506/early-orthodontic-tooth-movement-into-regenerative-bony-defects-a-case-report
#19
Hui-Chen Tsai, Chung-Chen Jane Yao, Man-Ying Wong
Early orthodontic tooth movement following regenerative surgery is controversial. In this case, during protraction of the maxillary right first premolar to substitute for the long-term missing maxillary right canine, Bio-Oss and Bio-Gide were used for lateral ridge augmentation at the area of the maxillary right lateral incisor and to cover the denuded surface at the buccal side of the first premolar. Orthodontic tooth movement (OTM) commenced 2 weeks after regenerative surgery. After 8 months, new bone formation was observed on the root surface of the first premolar during implant surgery...
July 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/28584862/corrigendum-to-comparative-study-on-the-efficacy-of-anorganic-bovine-bone-bio-oss-and-nanocrystalline-hydroxyapatite-ostim-in-maxillary-sinus-floor-augmentation
#20
Adileh Shirmohammadi, Leila Roshangar, Mohammad Taghi Chitsazi, Reza Pourabbas, Masoumeh Faramarzi, Nasrin Rahmanpour
[This corrects the article DOI: 10.1155/2014/967091.].
2017: International Scholarly Research Notices
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