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gastric antral vascular ectasia

Satyajeet Nighute, G S Shiddhapur
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
Arvind J Trindade, Sumant Inamdar, David Magier
No abstract text is available yet for this article.
January 2016: Endoscopy
Andrea Iannone, Mariabeatrice Principi, Michele Barone, Giuseppe Losurdo, Enzo Ierardi, Alfredo Di Leo
Gastrointestinal vascular malformations are responsible for 2-8% of all cases of bleeding and 30-40% of all obscure hemorrhages, being the most frequent cause of occult bleeding in older people. The aim of this review was to provide an up-to-date report about the use of octreotide in bleeding from both hereditary and acquired vascular malformations of the gastrointestinal tract. A systematic literature search was performed, using the keywords "gastrointestinal vascular malformation", "octreotide", "angiodysplasia", "portal hypertensive gastropathy", "gastric antral vascular ectasia", and "hereditary vascular malformations"...
September 2016: Clinics and Research in Hepatology and Gastroenterology
Cody M Lee, Diana Girnita, Arundhati Sharma, Surabhi Khanna, Jean M Elwing
Systemic sclerosis is a rare autoimmune disorder with a wide spectrum of clinical manifestations and a multitude of autoantibodies that are associated with it. In the past several years, advances in serologic testing have led to research indicating important prognostic and phenotypic associations with certain subsets of autoantibodies. In particular, anti-RNA polymerase III (anti-RNAP III) has been associated with diffuse cutaneous disease, scleroderma renal crisis, a temporal relationship with malignancy, myositis, synovitis, joint contractures, and gastric antral vascular ectasia...
2016: Case Reports in Rheumatology
Elliot Smith, Bezawit Tekola, James Patrie, Scott Cornella, Stephen Caldwell
BACKGROUND & AIMS: Gastric antral vascular ectasia is a relatively common endoscopic finding. Past studies have shown an association of gastric antral vascular ectasia with cirrhosis and autoimmune disorders. We aimed to re-examine these associations and to investigate a possible association of gastric antral vascular ectasia with features of the metabolic syndrome. METHODS: 135 patients with a diagnosis of gastric antral vascular ectasia from years 1995-2013 seen at the University of Virginia were identified from a clinical data repository and age and gender matched to a cohort of patients without gastric antral vascular ectasia undergoing endoscopy within the same time frame as the index cases...
July 27, 2016: American Journal of Medicine
Mohammed Elhendawy, Samah Mosaad, Walaa Alkhalawany, Lobna Abo-Ali, Mohamed Enaba, Aymen Elsaka, Asem A Elfert
BACKGROUND: Gastric antral vascular ectasia (GAVE) is characterized by mucosal and submucosal vascular ectasia causing recurrent hemorrhage and thus, chronic anemia, in patients with cirrhosis. Treatment with argon plasma coagulation (APC) is an effective and safe method, but requires multiple sessions of endoscopic therapy. Endoscopic band ligation (EBL) was found to be a good alternative for APC as a treatment for GAVE, especially in refractory cases. The aim of this prospective randomized controlled study was to evaluate the safety and efficacy of EBL, as compared to APC, in the treatment of GAVE and gastric fundal vascular ectasia (GFVE)...
June 2016: United European Gastroenterology Journal
Mihajlo Gjeorgjievski, Mitchell S Cappell
AIM: To describe the pathophysiology, clinical presentation, natural history, and therapy of portal hypertensive gastropathy (PHG) based on a systematic literature review. METHODS: Computerized search of the literature was performed via PubMed using the following medical subject headings or keywords: "portal" and "gastropathy"; or "portal" and "hypertensive"; or "congestive" and "gastropathy"; or "congestive" and "gastroenteropathy". The following criteria were applied for study inclusion: Publication in peer-reviewed journals, and publication since 1980...
February 8, 2016: World Journal of Hepatology
Chiara Marzano, Maddalena Zippi, Giampiero Traversa
No abstract text is available yet for this article.
February 2016: Endoscopy
Jennifer Wang, Jonathan G Stine, Scott L Cornella, Curtis K Argo, Steven M Cohn
BACKGROUND AND AIMS: Gastric antral vascular ectasia (GAVE) is commonly found in patients with cirrhosis, but it is also associated with other diseases in the absence of cirrhosis. Whether GAVE confers a different severity of gastrointestinal (GI) bleeding between patients with and without cirrhosis remains unknown. We aim to examine whether there is a difference in clinically significant GI bleeding due to GAVE in patients with or without cirrhosis. METHODS: This is a retrospective case-control study of patients who were diagnosed with GAVE between January 2000 and June 2014...
December 28, 2015: Journal of Clinical and Translational Hepatology
Kensuke Narukawa, Kazuhiko Kakihana, Takashi Fujiwara, Takeshi Kobayashi, Noriko Doki, Hisashi Sakamaki, Kazuteru Ohashi
This report describes three patients with chronic myelogenous leukemia who developed gastric antral vascular ectasia (GAVE) during treatment with imatinib mesylate (IM). Cessation and/or switching from IM to nilotinib resulted in the alleviation of gastrointestinal (GI) bleeding and ectatic lesions. Furthermore, GI bleeding recurred after the re-administration of IM in one patient. Thus, we consider that the occurrence of GAVE in our patients was induced by IM. Although the precise mechanism of IM-GAVE is not understood, all patients took at least 400 mg/day of IM at the onset of GAVE...
2016: Internal Medicine
Raphael Hernando Parrado, Hernan Nicolas Lemus, Paola Ximena Coral-Alvarado, Gerardo Quintana López
Introduction. Gastric antral vascular ectasia (GAVE) is a rare entity with unique endoscopic appearance described as "watermelon stomach." It has been associated with systemic sclerosis but the pathophysiological changes leading to GAVE have not been explained and still remain uncertain. Methods. Databases Medline, Scopus, Embase, PubMed, and Cochrane were searched for relevant papers. The main search words were "Gastric antral vascular ectasia," "Watermelon Stomach," "GAVE," "Scleroderma," and "Systemic Sclerosis...
2015: International Journal of Rheumatology
Hitendra Garg, Subhash Gupta, A C Anand, S L Broor
Portal hypertensive gastropathy (PHG) and gastric antral vascular ectasia (GAVE) are gastric mucosal lesions that mostly present as chronic anemia and rarely cause the acute gastrointestinal hemorrhage. Despite similar clinical manifestations, their pathophysiology and management are entirely different. PHG is seen exclusively in patients with portal hypertension, but GAVE can also be observed in patients with other conditions. Their diagnosis is endoscopic, and although generally each of them has a characteristic endoscopic appearance and distribution, there are cases in which the differential is difficult and must rely on histology...
September 2015: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
Johan F Hermansen, Henning Glerup
Gastric antral vascular ectasia (GAVE) is an important cause of gastro-intestinal bleeding. An 81-year-old male twice experienced severe anaemia as a result of GAVE. On the second occasion he was treated with endoscopic banding, and since he kept a stable haemoglobin level. GAVE has previously been treated which several different methods. Recently, endoscopic band ligation has, however, emerged as a new treatment of GAVE. Endoscopic band ligation has proven to be a safe and efficient treatment of GAVE.
October 26, 2015: Ugeskrift for Laeger
D A Papachristos, M Nikpour, C Hair, W M Stevens
Gastric antral vascular ectasia (GAVE) is a rare but important cause of upper gastrointestinal bleeding. It is commonly associated with autoimmune conditions such as systemic sclerosis, and standard treatment involves both supportive measures, as well as endoscopic interventional therapies. While the current therapies are effective for most patients, a few patients develop severe and refractory bleeding. Herein we report two cases of refractory GAVE in patients with diffuse scleroderma, which improved significantly after the administration of intravenous cyclophosphamide...
October 2015: Internal Medicine Journal
Samuel Han, Nabeel Chaudhary, Wahid Wassef
PURPOSE OF REVIEW: Portal hypertensive gastropathy (PHG) and gastric antral vascular ectasia (GAVE) are two types of upper gastrointestinal bleeding that may present similarly, but are managed very differently. This article reviews the pathogenesis and guidelines in management of both of these conditions with emphasis on recent advances in the field. RECENT FINDINGS: Off-label use of Hemospray has been shown in several case series to be useful in managing acute bleeding from PHG...
November 2015: Current Opinion in Gastroenterology
Nihar Shah, Yana Cavanagh, Dharmesh H Kaswala, Sohail Shaikh
The etiology of gastric antral vascular ectasia (GAVE) syndrome or gastric hyperplastic polyps (HPs) is not fully understood. We report a case of gastric HP arising in a patient treated with argon plasma coagulation (APC) for GAVE syndrome. Despite unclear etiologic progression, this and previously reported cases suggest a temporal relationship between the treatment of GAVE and HP. A 68-year-old male with a history of coronary artery disease, congestive heart failure and diabetes type II who initially presented with symptomatic anemia 2 weeks after starting aspirin and clopidogrel therapy...
July 2015: Journal of Natural Science, Biology, and Medicine
Aymeric Becq, Marine Camus, Gabriel Rahmi, Vincent de Parades, Philippe Marteau, Xavier Dray
INTRODUCTION: Radiofrequency ablation (RFA) is a well-validated treatment of dysplastic Barrett's esophagus. Other indications of endoscopic RFA are under evaluation. RESULTS: Four prospective studies (total 69 patients) have shown that RFA achieved complete remission of early esophageal squamous intra-epithelial neoplasia at a rate of 80%, but with a substantial risk of stricture. In the setting of gastric antral vascular ectasia, two prospective monocenter studies, and a retrospective multicenter study, (total 51 patients), suggest that RFA is efficacious in terms of reducing transfusion dependency...
August 2015: United European Gastroenterology Journal
Amandeep Singh, Anwaar A Khan, Robert Krall, Zafar K Mirza
Background. Gastric antral vascular ectasia (GAVE) also known as "watermelon stomach" (WS) is an uncommon cause of gastrointestinal (GI) blood loss. It typically presents in middle aged females. We are presenting a case of GAVE at an unusually early age with atypical symptoms. Case. A previously healthy 16 y/o Caucasian female presented to the ER with a one-month history of upper abdominal pain. Physical examination was benign except tenderness in the epigastric region. There were no significant findings on laboratory data...
2015: Case Reports in Medicine
Anita Basavaraj, Rahul Kulkarni, D B Kadam
Iron deficiency anaemia secondary to gastrointestinal bleeding is very common in the elderly. Gastric antral vascular ectasia (GAVE) syndrome, also known as watermelon stomach is an uncommon but significant cause of acute or chronic gastrointestinal blood loss in the elderly. It is characterised endoscopically by "watermelon stripes." It is more common in females than males, and manifests mostly as iron deficiency anaemia due to the gradual blood loss. Pathogenesis is unknown though several humoral factors have been proposed...
September 2014: Journal of the Association of Physicians of India
K A Patterson, P J Roberts-Thomson, S Lester, J A Tan, P Hakendorf, M Rischmueller, J Zochling, J Sahhar, P Nash, J Roddy, C Hill, M Nikpour, W Stevens, S M Proudman, J G Walker
OBJECTIVE: To determine the relationships between systemic sclerosis (SSc)-related autoantibodies, as well as their clinical associations, in a well-characterized Australian patient cohort. METHODS: Serum from 505 Australian SSc patients were analyzed with a commercial line immunoassay (EuroLine; Euroimmun) for autoantibodies to centromere proteins CENP-A and CENP-B, RNA polymerase III (RNAP III; epitopes 11 and 155), the 90-kd nucleolar protein NOR-90, fibrillarin, Th/To, PM/Scl-75, PM/Scl-100, Ku, topoisomerase I (topo I), tripartite motif-containing protein 21/Ro 52, and platelet-derived growth factor receptor...
December 2015: Arthritis & Rheumatology
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