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https://www.readbyqxmd.com/read/29667898/wernicke-s-encephalopathy-after-cardiac-surgery
#1
Yoshiyuki Nishimura
A 76-year-old woman who had been on hemodialysis for 3 years developed ischemic mitral valve insufficiency, tricuspid insufficiency, and chronic atrial fibrillation, and underwent cardiac surgery. On the 4th postoperative day, she experienced a sudden disturbance of consciousness, aphasia, and limb ataxia. Brain computed tomography and magnetic resonance imaging showed no abnormalities. Wernicke's encephalopathy was suspected and the patient was given vitamin B1, whereupon her symptoms gradually improved. On the 42nd postoperative day, she was free of neurological symptoms and discharged...
January 1, 2018: Asian Cardiovascular & Thoracic Annals
https://www.readbyqxmd.com/read/29666718/an-autopsy-case-of-misdiagnosed-wernicke-s-syndrome-after-intragastric-balloon-therapy
#2
Paola Vellante, Aldo Carnevale, Cristian D'Ovidio
Intragastric balloon (IGB) therapy is a widely used technique to counter obesity, and it is known to be safe and effective. Although there can be a high rate of side effects following IGB therapy, most are self-healing and they are mainly accommodative in nature. Few cases of Wernicke's syndrome under IGB therapy have been described in the literature, and to the best of our knowledge, none have been fatal. We present here a case of a 51-year-old woman who underwent IGB therapy over 8 months. Late diagnosed Wernicke's syndrome that first appeared as lower limb neuropathy progressively immobilized the patient, until she required bed rest...
2018: Case Reports in Gastrointestinal Medicine
https://www.readbyqxmd.com/read/29657895/restricted-single-isocenter-for-multiple-targets-dynamic-conformal-arc-rsimt-dca-technique-for-brain-stereotactic-radiosurgery-srs-planning
#3
Jenghwa Chang, A Gabriella Wernicke, Susan C Pannullo
Purpose/Objectives: In stereotactic radiosurgery (SRS), the multiple isocenters for multiple targets dynamic conformal arc (MIMT DCA) technique is traditionally used to treat multiple brain metastases, with one isocenter for each target. The single isocenter for multiple targets (SIMT) technique has recently been adopted to reduce the treatment time at the cost of plan quality. The objective of this study was to develop a restricted single isocenter for multiple targets DCA (RSIMT DCA) technique that can significantly reduce the treatment time but still maintain similar plan quality as the MIMT DCA technique...
2018: Journal of Radiosurgery and SBRT
https://www.readbyqxmd.com/read/29623164/wernicke-s-encephalopathy-5-years-after-a-whipple-procedure
#4
Mahmoud AbdelRazek, Crystal Han, Amanda Albrecht, Lobna Elsadek, Golnaz Yadollahikhales, Rabab Elsadek
No abstract text is available yet for this article.
April 2018: Neurohospitalist
https://www.readbyqxmd.com/read/29596284/a-case-of-wernicke-encephalopathy-developing-after-ileal-bypass-surgery
#5
Tülay Kamaşak, Sibel Kul, Mustafa Tuşat, Nezir Ozgun, Ali Cansu
Wernicke encephalopathy is an acute neurological problem resulting from thiamine deficiency and manifesting with mental confusion, oculomotor dysfunction, and ataxia. It is associated with alcohol dependence in adults. Preparatory factors include hyperemesis gravidarum, prolonged diarrhea, prolonged parental nutrition without vitamin support, absorption disorders, anorexia, cancer, and chemotherapy. Failure to consider the clinical findings and preparatory factors of this disease, which is rare in children, can delay diagnosis...
March 28, 2018: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29593640/vestibular-dysfunction-in-wernicke-s-encephalopathy-predominant-impairment-of-the-horizontal-semicircular-canals
#6
Seung-Han Lee, Sang-Hoon Kim, Ji-Min Kim, Alexander Andrea Tarnutzer
Background: Wernicke's encephalopathy (WE), a metabolic disorder due to thiamine deficiency, manifests with various neurological symptoms and signs. It has been known as a cause of vestibular dysfunction. Preliminary reports have proposed predominant involvement of the horizontal semicircular canals (HSCs). Objective: To better characterize the pattern of vestibular impairment in patients with WE using quantitative video head-impulse testing and to review the literature regarding this topic...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29563707/ocular-manifestations-in-a-case-of-wernicke-s-encephalopathy-due-to-hyperemesis-gravidarum
#7
Namitha Rachel Mathew, Sudha G Menon, Mariam Mathew
Wernicke's Encephalopathy (WE) is a potentially devastating disorder, which if not diagnosed and treated at the earliest, could lead to dangerous neurological and ophthalmological complications. We report the ocular manifestations of WE in a pregnant woman with hyperemesis gravidarum.
January 2018: Oman Journal of Ophthalmology
https://www.readbyqxmd.com/read/29561790/immune-specific-expression-and-estrogenic-regulation-of-the-four-estrogen-receptor-isoforms-in-female-rainbow-trout-oncorhynchus-mykiss
#8
Ayako Casanova-Nakayama, Elena Wernicke von Siebenthal, Christian Kropf, Elisabeth Oldenberg, Helmut Segner
Genomic actions of estrogens in vertebrates are exerted via two intracellular estrogen receptor (ER) subtypes, ERα and ERβ, which show cell- and tissue-specific expression profiles. Mammalian immune cells express ERs and are responsive to estrogens. More recently, evidence became available that ERs are also present in the immune organs and cells of teleost fish, suggesting that the immunomodulatory function of estrogens has been conserved throughout vertebrate evolution. For a better understanding of the sensitivity and the responsiveness of the fish immune system to estrogens, more insight is needed on the abundance of ERs in the fish immune system, the cellular ratios of the ER subtypes, and their autoregulation by estrogens...
March 21, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29561315/a-degenerative-form-of-mixed-transcortical-aphasia
#9
Leila Saadatpour, Usama Tariq, Alicia Parker, Leilani Doty, Kenneth M Heilman
Mixed transcortical aphasia (MTA) is characterized by decreased spontaneous speech, impaired naming, and poor comprehension, but with intact repetition. MTA has been reported to be the sequela of left hemisphere watershed infarction that isolates Wernicke's perisylvian arc. We report a 55-year-old right-handed woman who began having word-finding difficulty and then gradually developed impaired spontaneous speech, comprehension, and naming, but with intact repetition. Magnetic resonance imaging showed atrophy in the left frontal, parietal, and temporal lobes...
March 2018: Cognitive and Behavioral Neurology: Official Journal of the Society for Behavioral and Cognitive Neurology
https://www.readbyqxmd.com/read/29559372/a-double-dissociation-between-two-psychotic-phenotypes-periodic-catatonia-and-cataphasia
#10
Foucher Jack René, Zhang Yi Fan, Roser Mathilde, Lamy Julien, De Sousa Paulo Loureiro, Weibel Sébastien, Vidailhet Pierre, Mainberger Olivier, Berna Fabrice
Schizophrenia as a single liability model was confronted to the multiple psychotic phenotypes model proposed by the Wernicke-Kleist-Leonhard school, focusing on two: periodic catatonia (PC) and cataphasia (C). Both are stable and heritable psychotic phenotypes with no crossed liability and are coming with the buildup of specific residual symptoms: impairment of psychomotricity for PC and a specific disorganization of thought and language in C. Regional cerebral blood flow (rCBF) was used as a biomarker. We attempted to refute the single phenotype model by looking at relevant and specific rCBF anomalies for PC and C, that would exceed anomalies in common relative to controls (CTR), i...
March 17, 2018: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/29548317/probing-depth-is-an-independent-risk-factor-for-hba1c-levels-in-diabetic-patients-under-physical-training-a-cross-sectional-pilot-study
#11
Katharina Wernicke, Sven Zeissler, Frank C Mooren, Torsten Frech, Stephanie Hellmann, Meike Stiesch, Jasmin Grischke, Silvia Linnenweber, Bernhard Schmidt, Jan Menne, Anette Melk, Pascal Bauer, Andree Hillebrecht, Jörg Eberhard
BACKGROUND: This cross-sectional study investigates the potential association between active periodontal disease and high HbA1c levels in type-2-diabetes mellitus subjects under physical training. METHODS: Women and men with a diagnosis of non-insulin-dependent diabetes mellitus and ongoing physical and an ongoing exercise program were included. Periodontal conditions were assessed according to the CDC-AAP case definitions. Venous blood samples were collected for the quantitative analysis of HbA1c...
March 16, 2018: BMC Oral Health
https://www.readbyqxmd.com/read/29545765/clinical-characteristics-and-etiology-of-bilateral-vestibular-loss-in-a-cohort-from-central-illinois
#12
Jorge C Kattah
Background: Previous series of bilateral vestibular loss (BVL) identified numerous etiologies, but surprisingly, a cause in a significant number of cases remains unknown. In an effort to understand possible etiology and management strategies, a global effort is currently in progress. Here, I contribute my 10-year experience with both acute and chronic BVL during the 2007-2017 decade. Methods: This is a retrospective review of the charts and EMR of patients diagnosed with BVL in the last 10 years...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29542015/prediction-of-cardiac-death-after-adenosine-myocardial-perfusion-spect-based-on-machine-learning
#13
David Haro Alonso, Miles N Wernick, Yongyi Yang, Guido Germano, Daniel S Berman, Piotr Slomka
BACKGROUND: We developed machine-learning (ML) models to estimate a patient's risk of cardiac death based on adenosine myocardial perfusion SPECT (MPS) and associated clinical data, and compared their performance to baseline logistic regression (LR). We demonstrated an approach to visually convey the reasoning behind a patient's risk to provide insight to clinicians beyond that of a "black box." METHODS: We trained multiple models using 122 potential clinical predictors (features) for 8321 patients, including 551 cases of subsequent cardiac death...
March 14, 2018: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/29528160/presurgical-language-fmri-clinical-practices-and-patient-outcomes-in-epilepsy-surgical-planning
#14
Christopher F A Benjamin, Alexa X Li, Hal Blumenfeld, R Todd Constable, Rafeed Alkawadri, Stephan Bickel, Christoph Helmstaedter, Stefano Meletti, Richard Bronen, Simon K Warfield, Jurriaan M Peters, David Reutens, Monika Połczyńska, Dennis D Spencer, Lawrence J Hirsch
The goal of this study was to document current clinical practice and report patient outcomes in presurgical language functional MRI (fMRI) for epilepsy surgery. Epilepsy surgical programs worldwide were surveyed as to the utility, implementation, and efficacy of language fMRI in the clinic; 82 programs responded. Respondents were predominantly US (61%) academic programs (85%), and evaluated adults (44%), adults and children (40%), or children only (16%). Nearly all (96%) reported using language fMRI. Surprisingly, fMRI is used to guide surgical margins (44% of programs) as well as lateralize language (100%)...
March 12, 2018: Human Brain Mapping
https://www.readbyqxmd.com/read/29506843/pathologic-response-following-treatment-for-locally-advanced-rectal-cancer-does-location-matter
#15
William H Ward, Elin R Sigurdson, Andrew C Esposito, Karen J Ruth, Samuel M Manstein, Eric C Sorenson, Brian D Wernick, Jeffrey M Farma
BACKGROUND: Despite advances in the treatment of rectal adenocarcinoma, the management of locally advanced disease remains a challenge. The standard of care for patients with stages II and III rectal cancer includes neoadjuvant chemoradiation followed by total mesorectal excision and postoperative chemotherapy. Much effort has been dedicated to the identification of predictive factors associated with pathologic complete response (pCR). The aim of our study was to examine our institutional experience and determine whether any association exists between anatomic tumor location and the rate of pCR...
April 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29497752/the-relationship-between-confrontation-naming-and-story-gist-production-in-aphasia
#16
Jessica D Richardson, Sarah Grace Dalton, Davida Fromm, Margaret Forbes, Audrey Holland, Brian MacWhinney
Purpose: The purpose of this study was to examine the relationship between picture naming performance and the ability to communicate the gist, or essential elements, of a story. We also sought to determine if this relationship varied according to Western Aphasia Battery-Revised (WAB-R; Kertesz, 2007) aphasia subtype. Method: Demographic information, test scores, and transcripts of 258 individuals with aphasia completing 3 narrative tasks were retrieved from the AphasiaBank database...
March 1, 2018: American Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/29492359/excellent-outcomes-in-a-geriatric-patient-with-multiple-brain-metastases-undergoing-surgical-resection-with-cesium-131-implantation-and-stereotactic-radiosurgery
#17
Sean S Mahase, Diana Julie, Susan C Pannullo, Bhupesh Parashar, A Gabriella Wernicke
Stereotactic radiosurgery (SRS) is a minimally invasive, focal treatment option for brain metastases. Multiple studies support its use in various settings as an effective, comparable alternative to surgery and whole-brain radiation therapy (WBRT). Here, we present excellent outcomes in a 90-year-old patient who underwent SRS after initially presenting at age 84 with multiple brain metastases of an unknown primary, as well as undergoing SRS to a site of tumor recurrence that was initially treated with surgical resection and intraoperative cesium-131 (Cs-131) brachytherapy...
December 20, 2017: Curēus
https://www.readbyqxmd.com/read/29485342/geert-jan-rutten-the-broca-wernicke-doctrine-a-historical-and-clinical-perspective-on-the-localization-of-language-functions-heidelberg-springer-international-2017-306-xvii-pp-73-b-w-illustrations-38-illustrations-in-color-159-00-hardback-isbn-978-3-319-54632
#18
https://www.readbyqxmd.com/read/29482863/clinical-characteristics-and-outcomes-associated-with-high-dose-intravenous-thiamine-administration-in-patients-with-encephalopathy
#19
Zev M Nakamura, Jason R Tatreau, Donald L Rosenstein, Eliza M Park
BACKGROUND: Wernicke encephalopathy is a common neuropsychiatric syndrome due to thiamine deficiency. There is no consensus regarding thiamine dosing when Wernicke encephalopathy is suspected. A longstanding dosing strategy for Wernicke encephalopathy is 100mg daily, yet updated clinical guidelines suggest using high-dose intravenous (HDIV) thiamine. OBJECTIVE: To describe thiamine prescribing practices at a large, public academic hospital and investigate clinical characteristics and outcomes associated with HDIV thiamine in patients with encephalopathy who received IV thiamine...
January 11, 2018: Psychosomatics
https://www.readbyqxmd.com/read/29478423/early-detection-and-successful-treatment-of-wernicke-s-encephalopathy-in-outpatients-without-the-complete-classic-triad-of-symptoms-who-attended-a-psycho-oncology-clinic
#20
Hideki Onishi, Mayumi Ishida, Iori Tanahashi, Takao Takahashi, Kenji Ikebuchi, Yoshitada Taji, Hisashi Kato, Tatsuo Akechi
OBJECTIVE: Wernicke's encephalopathy (WE) is a neuropsychiatric disorder caused by a thiamine deficiency. Although WE has been recognized in cancer patients, it can be overlooked because many patients do not exhibit symptoms that are typical of WE, such as delirium, ataxia, or ocular palsy. Furthermore, outpatients with WE who intermittently present at psycho-oncology clinics have not been described as far as we can ascertain. METHOD: This report describes two patients who did not exhibit the complete classic triad of symptoms among a series with cancer and WE, and who attended a psycho-oncology outpatient clinic...
February 26, 2018: Palliative & Supportive Care
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