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https://www.readbyqxmd.com/read/29149083/co-precipitation-synthesis-and-optical-properties-of-mn-4-doped-hexafluoroaluminate-w-led-phosphors
#1
Tim Senden, Robin G Geitenbeek, Andries Meijerink
Mn(4+)-activated hexafluoroaluminates are promising red-emitting phosphors for white light emitting diodes (w-LEDs). Here, we report the synthesis of Na₃AlF₆:Mn(4+), K₃AlF₆:Mn(4+) and K₂NaAlF₆:Mn(4+) phosphors through a simple two-step co-precipitation method. Highly monodisperse large (~20 μm) smoothed-octahedron shaped crystallites are obtained for K₂NaAlF₆:Mn(4+). The large size, regular shape and small size distribution are favorable for application in w-LEDs. All Mn(4+)-doped hexafluoroaluminates show bright red Mn(4+) luminescence under blue light excitation...
November 17, 2017: Materials
https://www.readbyqxmd.com/read/29147012/piperidylmethyloxychalcone-improves-immune-mediated-acute-liver-failure-via-inhibiting-tak1-activity
#2
Sun Hong Park, Jeong-Ah Kwak, Sang-Hun Jung, Byeongwoo Ahn, Won-Jea Cho, Cheong-Yong Yun, Chang Seon Na, Bang Yeon Hwang, Jin Tae Hong, Sang-Bae Han, Youngsoo Kim
Mice deficient in the toll-like receptor (TLR) or the myeloid differentiation factor 88 (MyD88) are resistant to acute liver failure (ALF) with sudden death of hepatocytes. Chalcone derivatives from medicinal plants protect from hepatic damages including ALF, but their mechanisms remain to be clarified. Here, we focused on molecular basis of piperidylmethyloxychalcone (PMOC) in the treatment of TLR/MyD88-associated ALF. C57BL/6J mice were sensitized with D-galactosamine (GalN) and challenged with Escherichia coli lipopolysaccharide (LPS, TLR4 agonist) or oligodeoxynucleotide containing unmethylated CpG motif (CpG ODN, TLR9 agonist) for induction of ALF...
November 17, 2017: Experimental & Molecular Medicine
https://www.readbyqxmd.com/read/29138924/minimal-invasive-revision-of-adjacent-level-disease-after-mis-deformity-surgery
#3
Nils Hansen-Algenstaedt, Melanie Liem, SalahAddeen O Khalifah, Johannes Holz, Alf Giese
No abstract text is available yet for this article.
November 14, 2017: European Spine Journal
https://www.readbyqxmd.com/read/29129790/in-vitro-osteogenesis-by-intracellular-uptake-of-strontium-containing-bioactive-glass-nanoparticles
#4
Parichart Naruphontjirakul, Alexandra E Porter, Julian R Jones
Monodispersed strontium containing bioactive glass nanoparticles (Sr-BGNPs) with two compositions were synthesised, through a modified sol-gel Stöber process, wherein silica nanoparticles (SiO2-NPs) were formed prior to incorporation of calcium and strontium, with diameters of 90 ± 10 nm. The osteogenic response of a murine preosteoblast cell line, MC3T3-E1, was investigated in vitro for a nanoparticle concentration of 250 µg/mL with compositions of 87 mol% SiO2, 7 mol% CaO, 6 mol% SrO and 83 mol% SiO2, 3 mol% CaO, 14 mol% SrO...
November 9, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/29122206/the-evolution-of-accelerated-long-term-forgetting-evidence-from-the-time-study
#5
Sharon Savage, Serge Hoefeijzers, Fraser Milton, Claire Streatfield, Michaela Dewar, Adam Zeman
OBJECTIVE: Accelerated long-term forgetting (ALF) occurs when newly learned information decays faster than normal over extended delays. It has been recognised most frequently in temporal lobe epilepsy, including Transient Epileptic Amnesia (TEA), but can also be drug-induced. Little is known about the evolution of ALF over time and its impacts upon other memory functions, such as autobiographical memory (ABM). Here we investigate the long-term outcome of ALF and ABM in a group of patients with TEA and a single case of baclofen-induced ALF...
October 6, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/29117514/investigating-cascade-impactor-performance-using-a-modified-3d-printed-induction-port
#6
Kai Berkenfeld, Michael Bernauer, Jason T McConville, Alf Lamprecht
Based on a computer tomographic scan of a human trachea, a modified induction port (mIP), for use with the Next Generation Cascade Impactor, was manufactured using 3D printing technology. Standard United States Pharmacopoeia IP (USPIP) was compared to the mIP and a 3D printed version of the USPIP (USP3DIP) by analyzing different types of commercial salbutamol formulations for inhalation. Increased retention of particles in the mIP was found analyzing a pMDI formulation, leading to a decrease in the FPF from 28...
November 5, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/29116750/surface-charges-on-cdse-dot-cds-rod-nanocrystals-measuring-and-modeling-the-diffusion-of-exciton-fluorescence-rates-and-energies
#7
Sven-Hendrik Lohmann, Christian Strelow, Alf Mews, Tobias Kipp
By performing spectroscopic single-particle measurements at cryogenic temperatures over the course of hours we study both the spectral diffusion as well as the diffusion of the decay rates of the fluorescence emission of core/shell CdSe/CdS dot/rod nanoparticles. A special analysis of the measurements allow for a correlation of data for single neutral excitons only, undisturbed by the possible emission of other excitonic complexes. We find a nearly linear dependency of the fluorescence decay rate on the emission energy...
November 8, 2017: ACS Nano
https://www.readbyqxmd.com/read/29112935/histone-deacetylase-6-inhibitor-acy-1215-protects-against-experimental-acute-liver-failure-by-regulating-the-tlr4-mapk-nf-%C3%AE%C2%BAb-pathway
#8
Wen-Bin Zhang, Hai-Yue Zhang, Fang-Zhou Jiao, Lu-Wen Wang, Hong Zhang, Zuo-Jiong Gong
Histone deacetylase 6 (HDAC6) is considered a new target for anticancer, anti-inflammatory, and neurodegenerative treatment. ACY-1215 is a selective histone deacetylase 6 inhibitor, and it has been recognized as a potential anticancer and anti-inflammation drug. The aim of our study was to investigate whether ACY-1215 has protective effects on acute liver failure (ALF) in mice and explore its potential mechanism. Male C57/BL6 mice were divided into normal, model, and ACY-1215 groups. ACY-1215 (25mg/kg) and same amounts of saline were given to mice...
November 4, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29103621/appropriateness-of-anteroseptal-myocardial-infarction-nomenclature-evaluated-by-late-gadolinium-enhancement-cardiovascular-magnetic-resonance-imaging
#9
Joseph Allencherril, Yama Fakhri, Henrik Engblom, Einar Heiberg, Marcus Carlsson, Jean-Luc Dubois-Rande, Sigrun Halvorsen, Trygve S Hall, Alf-Inge Larsen, Svend Eggert Jensen, Hakan Arheden, Dan Atar, Peter Clemmensen, Dipan J Shah, Benjamin Cheong, Maria Sejersten, Yochai Birnbaum
BACKGROUND: In traditional literature, it appears that "anteroseptal" MIs with Q waves in V1-V3 involve basal anteroseptal segments although studies have questioned this belief. METHODS: We studied patients with first acute anterior Q-wave (>30ms) MI. All underwent late gadolinium enhancement (LGE) cardiac magnetic resonance imaging (MRI). RESULTS: Those with Q waves in V1-V2 (n=7) evidenced LGE >50% in 0%, 43%, 43%, 57%, and 29% of the basal anteroseptal, mid anteroseptal, apical anterior, apical septal segments, and apex, respectively...
October 6, 2017: Journal of Electrocardiology
https://www.readbyqxmd.com/read/29099086/sol-gel-synthesis-of-nanoscopic-complex-metal-fluorides
#10
Alexander Rehmer, Kerstin Scheurell, Gudrun Scholz, Erhard Kemnitz
The fluorolytic sol-gel synthesis for binary metal fluorides (AlF₃, CaF₂, MgF₂) has been extended to ternary and quaternary alkaline earth metal fluorides (CaAlF₅, Ca₂AlF₇, LiMgAlF₆). The formation and crystallization of nanoscopic ternary CaAlF₅ and Ca₂AlF₇ sols in ethanol were studied by (19)F liquid and solid state NMR (nuclear magnetic resonance) spectroscopy, as well as transmission electron microscopy (TEM). The crystalline phases of the annealed CaAlF₅, Ca₂AlF₇, and LiMgAlF₆ xerogels between 500 and 700 °C could be determined by X-ray powder diffraction (XRD) and (19)F solid state NMR spectroscopy...
November 2, 2017: Nanomaterials
https://www.readbyqxmd.com/read/29094550/a-a-dahl-svarer
#11
Alf A Dahl
No abstract text is available yet for this article.
October 31, 2017: Tidsskrift for Den Norske Lægeforening: Tidsskrift for Praktisk Medicin, Ny Række
https://www.readbyqxmd.com/read/29080224/safety-tolerability-and-pharmacokinetics-of-l-ornithine-phenylacetate-in-patients-with-acute-liver-injury-failure-and-hyperammonemia
#12
R Todd Stravitz, Michelle Gottfried, Valerie Durkalski, Robert J Fontana, A James Hanje, David Koch, Bilal Hameed, Daniel Ganger, Ram M Subramanian, Stan Bukofzer, William R Ravis, Kristen Clasen, Averell Sherker, Lanna Little, William M Lee
Cerebral edema remains a significant cause of morbidity and mortality in patients with acute liver failure (ALF) and has been linked to elevated blood ammonia levels. L-ornithine phenylacetate (OPA) may decrease ammonia by promoting its renal excretion as phenylacetylglutamine (PAGN), decreasing the risk of cerebral edema. We evaluated the safety, tolerability, and pharmacokinetics of OPA in patients with ALF and acute liver injury (ALI), including those with renal failure. Forty-seven patients with ALI/ALF and ammonia ≥60µM were enrolled...
October 28, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/29076021/antimonate-uptake-by-calcined-and-uncalcined-layered-double-hydroxides-effect-of-cationic-composition-and-m-2-m-3-molar-ratio
#13
Elisabetta Dore, Franco Frau
This study gives a contribution to assess the efficacy of some LDHs (layered double hydroxides) in Sb(V) uptake and understand the mechanisms involved in the removal process. Uncalcined nitrate Mg/Al LDHs and the mixed Mg-Al oxides derived from calcined carbonate Mg/Al LDHs mainly remove Sb(OH)6(-) from aqueous solution through the formation of a brandholzite-like phase (a non-LDH compound with general formula Mg[Sb(OH)6]2·6H2O), although with a different efficiency (< 50 and 90-100% of Sb(V) removed, respectively)...
October 26, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29074984/alf-a-strategy-for-identification-of-unauthorized-gmos-in-complex-mixtures-by-a-gw-ngs-method-and-dedicated-bioinformatics-analysis
#14
Alexandra Bogožalec Košir, Alfred J Arulandhu, Marleen M Voorhuijzen, Hongmei Xiao, Rico Hagelaar, Martijn Staats, Adalberto Costessi, Jana Žel, Esther J Kok, Jeroen P van Dijk
The majority of feed products in industrialised countries contains materials derived from genetically modified organisms (GMOs). In parallel, the number of reports of unauthorised GMOs (UGMOs) is gradually increasing. There is a lack of specific detection methods for UGMOs, due to the absence of detailed sequence information and reference materials. In this research, an adapted genome walking approach was developed, called ALF: Amplification of Linearly-enriched Fragments. Coupling of ALF to NGS aims for simultaneous detection and identification of all GMOs, including UGMOs, in one sample, in a single analysis...
October 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29070006/accelerated-long-term-forgetting-limited-to-the-recollection-component-of-recognition-memory-in-a-temporal-lobe-epileptic-patient
#15
Giovanni Augusto Carlesimo, Antonio Daniele, Maria Giovanna Lombardi, Giordano Lacidogna, Alfredo La Cara, Lucia Fadda, Carlo Caltagirone
Accelerated long-term forgetting (ALF) is a frequent finding in patients with temporal lobe epilepsy (TLE). Here we report the case of a TLE patient who complained of marked difficulties in remembering personal events and information even though repeated neuropsychological assessments had failed to detect any deficit on common laboratory memory tests. The patient underwent an experimental investigation that involved estimating recollection and familiarity processes in the performance on verbal and visual recognition tests, over intervals ranging from 10 minutes to 7 days...
October 26, 2017: Neurocase
https://www.readbyqxmd.com/read/29061060/relationship-between-ncrnas-and-gastric-cancer-meta-analysis
#16
Y J Sun, D Q Sun, R H Gong, X G Zhong, X T Liu, X L Meng
OBJECTIVE: This study was designed to investigate the action and mechanism of cordyceps polysaccharide on rat acute liver failure (ALF). METHODS: Sixty rats were randomly divided into five groups: normal group, model group, and cordyceps polysaccharide groups with high, middle and low doses (20, 10 and 5 mg/ml). Apoptosis was detected through TUNEL method. Protein expressions of caspase 1, IL-18, IL-10, VEGF, and SDF-1α in liver tissue are detected by Western Blot...
2017: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/29048969/school-based-curriculum-to-improve-depression-literacy-among-us-secondary-school-students-a-randomized-effectiveness-trial
#17
RANDOMIZED CONTROLLED TRIAL
Karen Swartz, Rashelle J Musci, Mary Beth Beaudry, Kathryn Heley, Leslie Miller, Clarissa Alfes, Lisa Townsend, Graham Thornicroft, Holly C Wilcox
OBJECTIVES: To determine the effectiveness of a universal school-based depression education program. METHODS: In 2012-2015, we matched 6679 students from 66 secondary schools into pairs by state (Maryland, Delaware, Pennsylvania, Michigan, and Oklahoma) and randomized to the Adolescent Depression Awareness Program (ADAP; n = 3681) or to a waitlist control condition (n = 2998). Trained teachers delivered ADAP as part of the health education curriculum to students aged 14 to 15 years...
December 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/29044729/outcome-comparison-of-liver-transplantation-for-hepatitis-a-related-versus-hepatitis-b-related-acute-liver-failure-in-adult-recipients
#18
Dong-Hwan Jung, Shin Hwang, Young-Suk Lim, Ki-Hun Kim, Chul-Soo Ahn, Deok-Bog Moon, Tae-Yong Ha, Gi-Won Song, Gil-Chun Park, Sung-Gyu Lee
Hepatitis A virus (HAV) can cause acute liver failure (ALF). This study compares outcomes between liver transplantation (LT) for HAV-related ALF (HAV-ALF) and LT for Hepatitis B virus (HBV)-related ALF (HBV-ALF). Of 3,616 adult LTs performed between January 2005 and December 2014, we performed LT for HAV-ALF recipients (n = 29) and LT for HBV-ALF recipients (n = 34). HAV-ALF group included 18 males and 11 females with mean age of 33.1 years. Graft survival rates in HAV-ALF and HBV-ALF were 65.5% and 88.0% (1 year) and 65...
October 17, 2017: Clinical Transplantation
https://www.readbyqxmd.com/read/29043612/the-a-like-faker-assay-for-measuring-yeast-chromosome-iii-stability
#19
Carolina A Novoa, J Sidney Ang, Peter C Stirling
The ability to rapidly assess chromosome instability (CIN) has enabled profiling of most yeast genes for potential effects on genome stability. The A-like faker (ALF) assay is one of several qualitative and quantitative marker loss assays that indirectly measure loss or conversion of genetic material using a counterselection step. The ALF assay relies on the ability to count spurious mating events that occur upon loss of the MATα locus of haploid Saccharomyces cerevisiae strains. Here, we describe the deployment of the ALF assay for both rapid and simple qualitative, and more in-depth quantitative analysis allowing determination of absolute ALF frequencies...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29042695/living-donor-liver-transplantation-for-acute-liver-failure-comparing-guidelines-on-the-prediction-of-liver-transplantation
#20
Kazuhiro Yoshida, Yuzo Umeda, Akinobu Takaki, Takeshi Nagasaka, Ryuichi Yoshida, Daisuke Nobuoka, Takashi Kuise, Kosei Takagi, Tetsuya Yasunaka, Hiroyuki Okada, Takahito Yagi, Toshiyoshi Fujiwara
Determining the indications for and timing of liver transplantation (LT) for acute liver failure (ALF) is essential. The King's College Hospital (KCH) guidelines and Japanese guidelines are used to predict the need for LT and the outcomes in ALF. These guidelines' accuracy when applied to ALF in different regional and etiological backgrounds may differ. Here we compared the accuracy of new (2010) Japanese guidelines that use a simple scoring system with the 1996 Japanese guidelines and the KCH criteria for living donor liver transplantation (LDLT)...
October 2017: Acta Medica Okayama
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