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https://www.readbyqxmd.com/read/29426988/rfa-versus-robotic-partial-nephrectomy-for-t1a-renal-cell-carcinoma-a-propensity-score-matched-comparison-of-mid-term-outcome
#1
Byung Kwan Park, In Hyuck Gong, Min Yong Kang, Hyun Hwan Sung, Hwang Gyun Jeon, Byong Chang Jeong, Seong Soo Jeon, Hyun Moo Lee, Seong Il Seo
OBJECTIVE: To compare oncological and functional mid-term outcomes following robotic partial nephrectomy (RPN) and radiofrequency ablation (RFA) for treating T1a renal cell carcinoma (RCC) using propensity score-matching. METHODS: Between December 2008-April 2016, 63 patients from each treatment group were propensity score-matched for age, sex, American Society of Anesthesiologists score, tumour size, tumour laterality, tumour histology, R.E.N.A.L. nephrometry score and preoperative estimated glomerular filtration rate (eGFR)...
February 9, 2018: European Radiology
https://www.readbyqxmd.com/read/29417641/role-of-computed-tomography-calculated-intraparenchymal-tumor-volume-in-assessment-of-patients-undergoing-partial-nephrectomy
#2
Raj Vikesh Tiwari, Chia Ming Ho, Hong Hong Huang, Henry Sun Sien Ho, Allen Soon Phang Sim
OBJECTIVES: To determine the complexity of renal masses by using an objective novel imaging parameter (intraparenchymal tumor volume) based on computed tomography scans, to correlate this parameter to perioperative outcomes and to the RENAL nephrometry score. METHODS: After institutional review board approval, 87 patients who underwent partial nephrectomy between 2012 and 2016 at Singapore General Hospital, Singapore, were retrospectively analyzed. Preoperative computed tomography intravenous pyelogram scans were reviewed by a single senior radiologist who calculated the intraparenchymal tumor volume...
February 8, 2018: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/29397572/robot-assisted-laparoscopic-partial-nephrectomy-versus-laparoscopic-partial-nephrectomy-a-propensity-score-matched-comparative-analysis-of-surgical-outcomes-and-preserved-renal-parenchymal-volume
#3
Hidekazu Tachibana, Toshio Takagi, Tsunenori Kondo, Hideki Ishida, Kazunari Tanabe
OBJECTIVES: To compare surgical outcomes, including renal function and the preserved renal parenchymal volume, between robot-assisted laparoscopic partial nephrectomy and laparoscopic partial nephrectomy using propensity score-matched analyses. METHODS: In total, 253 patients, with a normal contralateral kidney, who underwent laparoscopic partial nephrectomy (n = 131) or robot-assisted laparoscopic partial nephrectomy (n = 122) with renal arterial clamping between 2010 and 2015, were included...
February 4, 2018: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/29382448/ipsilateral-renal-function-preservation-following-minimally-invasive-partial-nephrectomy-the-effect-of-tumour-characteristics-and-warm-ischemic-time
#4
Ernest Chan, Shawna L Boyle, Jeffrey Campbell, Patrick P W Luke
INTRODUCTION: The relative impact of preoperative and perioperative variables on renal function following partial nephrectomy (PN) is controversial. To further investigate, we assess the effects of tumour complexity, warm ischemic time (WIT), and volume of resected renal parenchyma on ipsilateral renal function (IRF) outcomes following minimally invasive PN. METHODS: Of patients who underwent laparoscopic or robotic-assisted PN between 2002 and 2011 at our institution, 99 met our inclusion criteria...
October 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/29357404/robotic-partial-nephrectomy-for-large-renal-masses-a-multi-institutional-series
#5
Joan C Delto, David Paulucci, Michael W Helbig, Ketan K Badani, Daniel Eun, Ronney Abaza, James Porter, Ashok K Hemal, Akshay Bhandari
OBJECTIVES: To compare perioperative outcomes after RPN for cT2a (7 to <10cm) to cT1 tumors. Robotic partial nephrectomy (RPN) for T1 tumors has been shown to be safe, however, evaluation of PN for larger, complex tumors is lacking. MATERIALS AND METHODS: Patients with a cT1a (n=1358, 76.4%), cT1b (n=379, 21.3%) or cT2a (n=41, 2.3%) renal mass were identified from a multi-institutional RPN database. Intra and post-operative outcomes were compared for cT2a masses to cT1a and cT1b masses with multivariable regression models (i...
January 22, 2018: BJU International
https://www.readbyqxmd.com/read/29343913/comparison-of-renal-padua-and-c-index-scoring-systems-in-predicting-perioperative-outcomes-after-nephron-sparing-surgery
#6
Aditya P Sharma, Ravimohan Suryanarayana Mavuduru, Girdhar Singh Bora, Sudheer K Devana, Kiruthika Palani, Anupam Lal, Nandita Kakkar, Shrawan K Singh, Arup K Mandal
Introduction and Objective: The RENAL, PADUA and centrality index (C-index) nephrometry scoring systems (SS) have been individually evaluated for their role in predicting trifecta outcomes after nephron-sparing surgery (NSS). However, there is little data on their comparative superiority. The present study was designed to evaluate the predictive value of three SS and to assess interobserver reliability. Materials and Methods: Fifty patients undergoing NSS at our center between January 2014 and April 2016 were included in the study...
January 2018: Indian Journal of Urology: IJU: Journal of the Urological Society of India
https://www.readbyqxmd.com/read/29284123/conversion-of-robot-assisted-partial-nephrectomy-to-radical-nephrectomy-a-prospective-multi-institutional-study
#7
Sohrab Arora, Brian Chun, Rajesh K Ahlawat, Ronney Abaza, James Adshead, James R Porter, Benjamin Challacombe, Prokar Dasgupta, Giorgio Gandaglia, Daniel A Moon, T B Yuvaraja, Umberto Capitanio, Alessandro Larcher, Francesco Porpiglia, Alexander Mottrie, Mahendra Bhandari, Craig Rogers
OBJECTIVES: To assess the incidence, and factors affecting conversion from robot-assisted partial nephrectomy (RAPN) to radical nephrectomy. METHODS: Between November 2014 and February 2017, 501 patients underwent attempted RAPN by 22 surgeons at 14 centers in nine countries within the Vattikuti Collaborative Quality Initiative database. Patients were permanently logged for RAPN prior to surgery and were analysed on an intention-to-treat basis. Multivariable logistic regression with backward stepwise selection of variables was done to assess the factors associated with conversion to radical nephrectomy...
December 25, 2017: Urology
https://www.readbyqxmd.com/read/29278580/retroperitoneal-versus-transperitoneal-robotic-assisted-laparoscopic-partial-nephrectomy-a-matched-pair-bicenter-analysis-with-cost-comparison-using-time-driven-activity-based-costing
#8
Aaron A Laviana, Hung-Jui Tan, Jim C Hu, Alon Z Weizer, Sam S Chang, Daniel A Barocas
PURPOSE OF REVIEW: To perform a bicenter, retrospective study of perioperative outcomes of retroperitoneal versus transperitoneal robotic-assisted laparoscopic partial nephrectomy (RALPN) and assess costs using time-driven activity-based costing (TDABC). We identified 355 consecutive patients who underwent RALPN at University of California Los Angeles and the University of Michigan during 2009-2016. We matched according to RENAL nephrometry score, date, and institution for 78 retroperitoneal versus 78 transperitoneal RALPN...
December 22, 2017: Current Opinion in Urology
https://www.readbyqxmd.com/read/29174503/external-validation-of-the-arterial-based-complexity-score-and-first-head-to-head-comparison-with-the-r-e-n-a-l-and-padua-scores-and-c-index
#9
Alessandro Antonelli, Alessandro Veccia, Marco Sandri, Maria Chiara Furlan, Stefano Recenti, Mario Sodano, Carlotta Palumbo, Alberto Cozzoli, Claudio Simeone
INTRODUCTION: We performed an external validation of the arterial-based complexity (ABC) score using a head-to-head comparison with the R.E.N.A.L. (radius, exophytic/endophytic tumor properties, nearness of tumor to deepest portion of collecting system or sinus, anterior/posterior descriptor, location relative to the polar line), PADUA (preoperative aspects and dimension for anatomic classification of renal tumors), and C-index scores for the prediction of surgical outcomes after partial nephrectomy...
November 7, 2017: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/29151960/r-e-n-a-l-nephrometry-score-a-preoperative-risk-factor-predicting-the-fuhrman-grade-of-clear-cell-renal-carcinoma
#10
Shao-Hao Chen, Yu-Peng Wu, Xiao-Dong Li, Tian Lin, Qing-Yong Guo, Ye-Hui Chen, Jin-Bei Huang, Yong Wei, Xue-Yi Xue, Qing-Shui Zheng, Ning Xu
Objective: The purpose of this study was to evaluate the efficacy and feasibility of the R.E.N.A.L. Nephrometry Score to postoperatively predict high-grade clear-cell renal carcinoma (ccRCC). Methods: The study included 288 patients diagnosed with ccRCC who had complete CT/CTA data and R.E.N.A.L. Nephrometry Scores and underwent renal surgery at our center between January 2012 and December 2015. The relationship between the pathological grade of renal masses and R.E.N.A.L. Nephrometry Score was evaluated. Results: Univariate analysis indicated that diagnostic modality, cystic necrosis, enlargement of the regional lymph node, distant metastasis, clinical T stage, TNM stage, surgical modality, tumor size, nearness of the tumor to the collecting system or sinus, total Nephrometry Score and individual anatomic descriptor components were significantly associated with postoperative tumor grade (P < 0...
2017: Journal of Cancer
https://www.readbyqxmd.com/read/29135137/-renal-function-after-laparoscopic-partial-nephrectomy-with-superselective-balloon-embolization-of-renal-artery
#11
A V Maksimov, A G Martov, L P Pavlov
AIM: To evaluate the functional state of the renal parenchyma after partial nephrectomy, depending on surgical technique. MATERIALS AND METHODS: The study comprised 21 patients with kidney neoplasms of stage T1-2N0M0. The patients underwent either laparoscopic partial nephrectomy with superselective balloon embolization of the renal artery (study group, n=11), or partial nephrectomy with vascular clamping (control group, n=10). The mean age of the patients in the study group (3 men and 8 women) was 56...
October 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/29113767/renal-functional-outcome-of-partial-nephrectomy-for-complex-r-e-n-a-l-score-tumors-with-or-without-neoadjuvant-sunitinib-a-multicenter-analysis
#12
Michelle L McDonald, Brian R Lane, Juan Jimenez, Hak J Lee, Kendrick Yim, Ahmet Bindayi, Zachary A Hamilton, Charles A Field, Aaron S Bloch, Sumi Dey, Sabrina Noyes, Rana McKay, Frederick Millard, Brian I Rini, Steven C Campbell, Ithaar H Derweesh
BACKGROUND: Sunitinib might optimize the feasibility of partial nephrectomy (PN) for complex renal tumors with imperative indications. We compared the renal functional outcomes of patients with complex renal masses who had undergone sunitinib before PN with those of patients who had not required neoadjuvant sunitinib before PN. PATIENTS AND METHODS: We performed a multicenter retrospective analysis of patients with renal cell carcinoma who had undergone PN for a complex renal mass (R...
September 25, 2017: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/29104784/external-validation-of-four-nephrometry-scores-for-trans-peritoneal-robotic-partial-nephrectomy
#13
Bhavan Prasad Rai, Amit Patel, Ahmed Abroaf, Narin Suleyman, Shanmugasundaram Gowriemohan, Venkat Prasad, Nikhil Vasdev, Jim Adshead
Introduction: External validation of four nephrometry scores (NS): Centrality index (C-index), arterial based complexity (ABC), preoperative aspects and dimensions used for an anatomical (PADUA) and radius expohytic/endophytic nearness anterior/posterior location (RENAL) scoring systems in patients who have undergone trans-peritoneal robotic assisted partial nephrectomy (RAPN). Material and methods: A prospective database for RAPN has been maintained. Individual NSs were performed on 3-dimensional reconstructions of MDCT/MRI studies retrospectively by a board certified uroradiologist...
2017: Central European Journal of Urology
https://www.readbyqxmd.com/read/29092632/comparison-of-kidney-function-in-the-early-postoperative-period-in-transperitoneal-robot-assisted-laparoscopic-partial-nephrectomy-between-anterior-and-posterior-renal-tumors-a-propensity-score-matched-study
#14
Toshio Takagi, Tsunenori Kondo, Kazuhiko Yoshida, Hirohito Kobayashi, Junpei Iizuka, Masayoshi Okumi, Hideki Ishida, Kazunari Tanabe
Objective To compare early postoperative renal function in transperitoneal robot assisted laparoscopic partial nephrectomy (RAPN) for anterior and posterior renal tumors. Patients and Methods This study included 227 patients who underwent transperitoneal RAPN for anterior or posterior renal tumors. Tumor position was defined by RENAL nephrometry score. To minimize selection bias between anterior and posterior tumors, patient variables were adjusted using 1:1 propensity score matching. Results Of the 227 patients, 125 were classified as having anterior tumors and 102 as having posterior tumors...
November 1, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/29072806/strategies-for-success-a-multi-institutional-study-on-robot-assisted-partial-nephrectomy-for-complex-renal-lesions
#15
Derek B Hennessey, Gavin Wei, Daniel Moon, Ned Kinnear, Damien M Bolton, Nathan Lawrentschuk, Yee K Chan
OBJECTIVE: To describe our technique, illustrated with images and videos, of robot-assisted partial nephrectomy (RAPN) for challenging renal tumours. PATIENTS AND METHODS: A study of 249 patients who underwent RAPN in multiple institutions was performed. Patients were identified using prospective RAPN databases. Complex renal lesion were defined as those with a RENAL nephrometry score ≥10. Data were analysed and differences among groups examined. RESULTS: A total of 31 (12...
October 26, 2017: BJU International
https://www.readbyqxmd.com/read/29048228/predictive-factors-for-achieving-superior-pentafecta-outcomes-following-robot-assisted-partial-nephrectomy-in-patients-with-localized-renal-cell-carcinoma
#16
Minyong Kang, In-Hyuck Gong, Hwi Jun Park, Hyun Hwan Sung, Hwang Gyun Jeon, Byong Chang Jeong, Seong Soo Jeon, Hyun Moo Lee, Han Yong Choi, Seong Il Seo
PURPOSE: To examine the perioperative outcomes following robot-assisted partial nephrectomy (RAPN) in patients with localized renal cell carcinoma (RCC) and to identify the predictors of Pentafecta achievement following RAPN. MATERIALS AND METHODS: We retrospectively analyzed the data from 362 patients with RCC who underwent RAPN from 2008 to 2016. The criteria for Pentafecta achievement was defined as the Trifecta [warm ischemia time (WIT) ≤ 25 minutes, negative surgical margin, and no significant perioperative complications]; with the addition of renal function preservation, including over 90% preservation of the estimated-glomerular filtration rate (e-GFR); and no stage upgrade of chronic kidney disease at 1 year after surgery...
October 19, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/29044535/incidence-and-histologic-features-of-mixed-renal-tumors
#17
Neil J Kocher, Chris Rjepaj, Erik Lehman, Jay D Raman
BACKGROUND AND OBJECTIVES: Guidelines for management of renal cell carcinoma (RCC) incompletely address the implications of mixed renal tumor histology. We investigate the incidence of mixed renal tumors identified at renal surgery and determine the association with pathologic features. METHODS: Institutional kidney tumor database was reviewed to identify 536 patients who underwent partial or radical nephrectomy. Clinical, demographic, and pathologic data were collected...
October 16, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28954531/is-off-clamp-always-beneficial-during-robotic-partial-nephrectomy-a-propensity-score-matched-comparison-of-clamp-technique-in-patients-with-two-kidneys
#18
Daniel C Rosen, David J Paulucci, Ronney Abaza, Daniel D Eun, Akshay Bhandari, Ashok K Hemal, Ketan K Badani
OBJECTIVE: The majority of patients undergoing partial nephrectomy (PN) present with a clinical T1a tumor with both kidneys present. Some groups have advocated using off-clamp (Off-C) techniques to eliminate warm ischemia whenever possible, even when elective. We evaluated whether Off-C technique during robotic PN (RPN) provides any functional benefit over main arterial clamping (MAC) in these patients. Subjects/Patients and Methods: A total of 351 patients with a R.E.N.A.L. nephrometry score (RNS) <10, T1a tumor, and two kidneys who underwent RPN from five high-volume surgeons between 2008 and 2016 were retrospectively identified from a multi-institutional database...
November 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28941921/external-validation-of-contact-surface-area-as-a-predictor-of-post-operative-renal-function-in-patients-undergoing-partial-nephrectomy
#19
Miki Haifler, Benjamin T Ristau, Andrew M Higgins, Marc C Smaldone, Alexander Kutikov, Amnon Zisman, Robert G Uzzo
PURPOSE: To externally validate a mathematical formula for tumor contact surface area (CSA) as a predictor of post-operative renal function in patients undergoing partial nephrectomy for renal cell carcinoma. MATERIALS AND METHODS: A prospectively maintained kidney cancer database was queried for patients who underwent partial nephrectomy between 2014 and 2016. CSA was calculated using data obtained from pre-operative cross sectional imaging. The correlation between CSA and peri-operative variables was examined...
September 20, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28941919/local-tumor-bed-recurrence-following-partial-nephrectomy-in-patients-with-small-renal-masses
#20
Erika L Wood, Mehrad Adibi, Wei Qiao, Jessica Brandt, Miao Zhang, Pheroze Tamboli, Surena F Matin, Christopher G Wood, Jose A Karam
PURPOSE: We examined the incidence, characteristics and treatment of patients with tumor bed recurrence after partial nephrectomy. MATERIALS AND METHODS: We retrospectively reviewed the charts of 2,256 patients with sporadic small renal masses treated with partial nephrectomy between 2000 and 2014. Local tumor bed recurrence was strictly defined as detection of a new enhancing lesion 1) specifically in the surgical defect or 2) in the same region (eg lower pole) as the partial nephrectomy site...
February 2018: Journal of Urology
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