Yuling Zheng, Jinping Huang, Ying Mai, Xiaoling Li, Zhongqi Zhang
OBJECTIVE: Propofol-opioids are the most common drug combination and can reduce the dose of propofol and the incidence of adverse events in painless artificial abortion. We hypothesized that butorphanol may reduce the median effective dose (ED50 ) of propofol, propofol injection pain, and postoperative uterine contraction pain. METHODS: This was a randomized, double-blind, controlled study. A total of 54 female patients, who had ASA I or II, aged 18-49 years, undergoing painless artificial abortion, were randomly assigned into two groups, namely, Group P (propofol) and Group PB (propofol plus 10 μg/kg butorphanol)...
2023: Frontiers in Medicine