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https://www.readbyqxmd.com/read/28922361/impact-of-four-different-recumbencies-on-the-distribution-of-ventilation-in-conscious-or-anaesthetized-spontaneously-breathing-beagle-dogs-an-electrical-impedance-tomography-study
#1
Tamas D Ambrisko, Johannes P Schramel, Ulrike Auer, Yves P S Moens
The aim was to examine the effects of recumbency and anaesthesia on distribution of ventilation in beagle dogs using Electrical Impedance Tomography (EIT). Nine healthy beagle dogs, aging 3.7±1.7 (mean±SD) years and weighing 16.3±1.6 kg, received a series of treatments in a fixed order on a single occasion. Conscious dogs were positioned in right lateral recumbency (RLR) and equipped with 32 EIT electrodes around the thorax. Following five minutes of equilibration, two minutes of EIT recordings were made in each recumbency in the following order: RLR, dorsal (DR), left (LLR) and sternal (SR)...
2017: PloS One
https://www.readbyqxmd.com/read/28920785/detomidine-and-butorphanol-for-standing-sedation-in-a-range-of-zoo-kept-ungulate-species
#2
Tim Bouts, Joanne Dodds, Karla Berry, Abdi Arif, Polly Taylor, Andrew Routh, Frank Gasthuys
General anesthesia poses risks for larger zoo species, like cardiorespiratory depression, myopathy, and hyperthermia. In ruminants, ruminal bloat and regurgitation of rumen contents with potential aspiration pneumonia are added risks. Thus, the use of sedation to perform minor procedures is justified in zoo animals. A combination of detomidine and butorphanol has been routinely used in domestic animals. This drug combination, administered by remote intramuscular injection, can also be applied for standing sedation in a range of zoo animals, allowing a number of minor procedures...
September 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28865107/effect-of-body-position-exercise-and-sedation-on-estimation-of-pulmonary-artery-pressure-in-dogs-with-degenerative-atrioventricular-valve-disease
#3
J D Rhinehart, K E Schober, B A Scansen, V Yildiz, J D Bonagura
BACKGROUND: Severity of pulmonary hypertension (PH) in dogs is related to clinical signs and prognosis. HYPOTHESIS/OBJECTIVES: We hypothesized that Doppler echocardiographic (DE) indices of pulmonary artery pressure (PAP) and pulmonary vascular resistance (PVR) are influenced by independent factors that create clinically important variability of DE-based estimates of PH in dogs. ANIMALS: Thirty-eight client owned dogs with naturally acquired degenerative atrioventricular valve disease and tricuspid regurgitation (TR)...
September 2, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28836839/antinociceptive-efficacy-of-intramuscular-administration-of-morphine-sulfate-and-butorphanol-tartrate-in-tegus-salvator-merianae
#4
William P Leal, Adriano B Carregaro, Thais F Bressan, Shayne P Bisetto, Cristiano F Melo, Kurt K Sladky
OBJECTIVE To evaluate the antinociceptive efficacy of IM morphine sulfate or butorphanol tartrate administration in tegus (Salvator merianae). ANIMALS 6 healthy juvenile (12- to 24-month-old) tegus (mean ± SD body weight, 1,484 ± 473 g). PROCEDURES In a crossover study design, tegus were randomly assigned to treatment order, with a minimum washout period of 15 days between treatments. Each of 5 treatments was administered IM in a forelimb: saline (0.9% NaCl) solution (0.5 mL), morphine sulfate (5 or 10 mg/kg), or butorphanol tartrate (5 or 10 mg/kg)...
September 2017: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/28828865/comparison-of-thiafentanil-medetomidine-to-etorphine-medetomidine-immobilisation-of-impalas-i-aepyceros-melampus-i
#5
Gareth E Zeiler, Leith C R Meyer
Impalas (Aepyceros melampus) are increasingly valuable in the South African wildlife industry, and there is a greater need to chemically immobilise them, ideally with minimal risk. This study aimed to compare the times to recumbency and physiological effects of thiafentanilmedetomidine versus etorphine-medetomidine immobilisation. A combination of thiafentanil (2 mg) + medetomidine (2.2 mg) and etorphine (2 mg) + medetomidine (2.2 mg) was administered (to nine impalas; crossover design) via a dart. After darting, a stopwatch was started to record times to recumbency (time from darting until recumbent without attempts to stand)...
August 4, 2017: Journal of the South African Veterinary Association
https://www.readbyqxmd.com/read/28822974/sedative-and-cardiopulmonary-effects-of-dexmedetomidine-infusions-randomly-receiving-or-not-butorphanol-in-standing-horses
#6
Luíza Quintão Medeiros, Miguel Gozalo-Marcilla, Polly M Taylor, Daniela Campagnol, Flávia Augusta de Oliveira, Marcos Jun Watanabe, Antonio José de Araujo Aguiar
Dexmedetomidine (DEX) alone, or combined with butorphanol (BUT), may be administered by constant rate infusions (CRIs) in standing horses. This blinded, randomised, crossover study in six healthy adult horses aimed to determine the sedative and cardiopulmonary effects of DEX (dexmedetomidine (3.5 µg/kg+5 µg/kg/hour CRI) and DEX/BUT (dexmedetomidine (3.5 µg/kg+3.5 µg/kg/hour CRI) and butorphanol (20 µg/kg+24 µg/kg/hour CRI)). Head height above ground (HHAG), ataxia, responses to tactile/auditory stimuli and cardiopulmonary variables were recorded before, at 5/15/30/60/90 minutes and after CRIs terminated (15/30/60 minutes)...
August 19, 2017: Veterinary Record
https://www.readbyqxmd.com/read/28796153/optimum-drug-combinations-for-the-sedation-of-growing-boars-prior-to-castration
#7
Heidi S Lehmann, Dominique Blache, Eleanor Drynan, Pema Tshewang, David J C Blignaut, Gabrielle C Musk
Juvenile male pigs were sedated for castration. Eight five-month old boars were sedated twice (two weeks apart) with a combination of detomidine (0.1 mg/kg), midazolam (0.2 mg/kg) and either butorphanol (0.2 mg/kg) (Group MDB, n = 8) or morphine (0.2 mg/kg) (Group MDM, n = 8) intramuscularly. The boars were positioned in lateral recumbency and lidocaine (200 mg total) was injected into the testicle and scrotal skin. Castration of a single testicle was performed on two occasions. Sedation and reaction (to positioning and surgery) scores, pulse rate, respiratory rate, haemoglobin oxygen saturation, body temperature, arterial blood gas parameters and the times to immobility and then recovery were recorded...
August 10, 2017: Animals: An Open Access Journal From MDPI
https://www.readbyqxmd.com/read/28765033/assessment-of-butorphanol-azaperone-medetomidine-combination-as-anesthesia-for-semen-collection-and-evaluation-of-semen-quality-in-white-tailed-deer-odocoileus-virginianus
#8
S M Kirschner, R Rodenkirch
The aim of this current study was to evaluate the level of anesthesia produced by a combination of butorphanol-azaperone-medetomidine (BAM) for semen collection by electroejaculation on captive white-tailed bucks (Odocoileus virginianus). Ten male white-tailed deer, weighing 68.2-115.9kg, ranging in age from one to four years were randomly selected from housing pens and anesthetized with the BAM drug combination at a dose volume of 2.0mL each. Semen was collected from each animal using a standard cervid electroejaculation protocol while under BAM anesthesia...
July 25, 2017: Animal Reproduction Science
https://www.readbyqxmd.com/read/28738000/comparison-of-cardiac-output-measured-by-use-of-computed-tomography-and-thermodilution-in-dogs
#9
Sharon Tenenbaum, Fernando L Garcia-Pereira, Clifford R Berry, Tori Obert
OBJECTIVE To compare cardiac output (CO) measured by use of CT coronary angiography and thermodilution (criterion-referenced standard) at various CO values, record adverse effects, and determine the time needed to measure CO. ANIMALS 5 healthy purpose-bred Beagles (2 males and 3 females). PROCEDURES A prospective nonrandomized crossover study was conducted. Dogs were premedicated with butorphanol tartrate (0.2 mg•kg(-1), IM). Anesthesia was induced by IV administration of etomidate (1 to 2 mg•kg(-1)) and midazolam (0...
August 2017: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/28717545/low-dose-lignocaine-butorphanol-vs-low-dose-bupivacaine-for-spinal-anaesthesia-in-day-care-urological-surgeries-a-prospective-randomized-control-trial
#10
Shahil Rameshbhai Khant, Rajeev Chaudhari, Rishikesh Arun Kore, Shirish Bhagwat, Ranjan Purushottam Jakhalekar
OBJECTIVE: A local anaesthetic with fast onset, short and reliable duration of anaesthesia may be preferable for day care urological surgeries. Low dose lignocaine is believed to act faster and to have a shorter duration of action than low dose bupivacaine. Use of lignocaine for spinal anesthesia is discouraged now a days because of rare reports of transient neurological symptoms. The purpose of this study was to compare effectiveness and safety of low dose of lignocaine + butorphanol against low dose of bupivacaine for day care urological surgeries...
June 2017: Turkish Journal of Urology
https://www.readbyqxmd.com/read/28716685/the-use-of-alfaxalone-for-premedication-induction-and-maintenance-of-anaesthesia-in-pigs-a-pilot-study
#11
Sarah E Bigby, Jennifer E Carter, Sébastien Bauquier, Thierry Beths
OBJECTIVE: The evaluation of alfaxalone as a premedication agent and intravenous anaesthetic in pigs. STUDY DESIGN: Prospective, clinical trial. ANIMALS: Nine healthy, 6-8-week-old female Landrace pigs weighing 22.2 ± 1.0 kg, undergoing epidural catheter placement. METHODS: All pigs were premedicated with 4 mg kg(-1) alfaxalone, 40 μg kg(-1) medetomidine and 0.4 mg kg(-1) butorphanol administered in the cervical musculature...
March 21, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28687474/alfaxalone-for-maintenance-of-anaesthesia-in-ponies-undergoing-field-castration-continuous-infusion-compared-with-intravenous-boluses
#12
Julia Deutsch, Abel Ekiri, Annemarie de Vries
OBJECTIVE: To compare alfaxalone as continuous intravenous (IV) infusion with intermittent IV injections for maintenance of anaesthesia in ponies undergoing castration. STUDY DESIGN: Prospective, randomized, 'blinded' clinical study. ANIMALS: A group of 33 entire male Welsh ponies undergoing field castration. METHODS: After preanaesthetic medication with IV detomidine (10 μg kg(-1)) and butorphanol (0.05 mg kg(-1)), anaesthesia was induced with IV diazepam (0...
April 14, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28684240/intramuscular-injection-of-alfaxalone-in-combination-with-butorphanol-for-sedation-in-cats
#13
Julia Deutsch, Colette Jolliffe, Emma Archer, Elizabeth A Leece
OBJECTIVE: To assess quality of sedation following intramuscular (IM) injection of two doses of alfaxalone in combination with butorphanol in cats. STUDY DESIGN: Prospective, randomized, 'blinded' clinical study. ANIMALS: A total of 38 cats undergoing diagnostic imaging or noninvasive procedures. METHODS: Cats were allocated randomly to be administered butorphanol 0.2 mg kg(-1) combined with alfaxalone 2 mg kg(-1) (group AB2) or 5 mg kg(-1) (group AB5) IM...
March 6, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28674271/pharmacological-properties-of-various-anesthetic-protocols-in-10-day-old-neonatal-rats
#14
Atsushi Tsukamoto, Yui Konishi, Takako Kawakami, Chiharu Koibuchi, Reiichiro Sato, Eiichi Kanai, Tomo Inomata
In general, the anesthesia in neonates involves high risk. Although hypothermic anesthesia is recommended in rats up to the age of 7 days, neonatal anesthesia for later periods has not been standardized. The present study investigated the pharmacological properties of conventional anesthetic protocols in 10-day-old SD rats. The rats were anesthetized with four anesthetics: a combination of ketamine and xylazine (K/X); a combination of medetomidine, midazolam, and butorphanol (M/M/B); isoflurane; and sevoflurane...
June 30, 2017: Experimental Animals
https://www.readbyqxmd.com/read/28663623/comparison-of-epidural-butorphanol-with-neostigmine-and-epidural-sufentanyl-with-neostigmine-for-first-stage-of-labor-analgesia-a-randomized-controlled-trial
#15
Manoj Chaurasia, Ashok Kumar Saxena, Geetanjali T Chilkoti
BACKGROUND: Epidural administration of neostigmine appears to be safe in the obstetric population. Recently, few studies have concluded 10 μg sufentanil to be an effective adjuvant with epidural neostigmine in providing labor analgesia. However, no study has evaluated the analgesic effect of epidural butorphanol with neostigmine for the same. MATERIALS AND METHODS: The parturients were randomly allocated to one of the three study groups - Group A (n = 30) received butorphanol 1 mg and neostigmine 7 μg/kg...
April 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28651573/efficacy-and-safety-of-oral-robenacoxib-tablet-for-the-treatment-of-pain-associated-with-soft-tissue-surgery-in-client-owned-dogs
#16
Gabriele Friton, Caryn Marie Thompson, Daniela Karadzovska, Stephen King, Jonathan N King
BACKGROUND: Non-steroidal anti-inflammatory drugs (NSAIDs) have been proven to be effective in controlling peri-operative pain in dogs. Robenacoxib is an NSAID with high selectivity for the cyclooxygenase (COX)-2 isoform. The objective of this study was to assess the efficacy and safety of an oral tablet formulation of robenacoxib in client-owned dogs undergoing soft tissue surgery. The study was a prospective, multi-center, randomized, masked, placebo-controlled, parallel-group clinical trial...
June 26, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28603217/effects-of-a-mixture-of-medetomidine-midazolam-and-butorphanol-on-anesthesia-and-blood-biochemistry-and-the-antagonizing-action-of-atipamezole-in-hamsters
#17
Teppei Nakamura, Naoya Karakida, Ai Dantsuka, Osamu Ichii, Yaser Hosny Ali Elewa, Yasuhiro Kon, Ken-Ichi Nagasaki, Hideki Hattori, Tomoji Yoshiyasu
Syrian golden hamsters (Mesocricetus auratus) are useful laboratory rodents for studying human infectious diseases, metabolic diseases and cancer. In other rodents, such as mice and rats, a mixture of medetomidine, midazolam and butorphanol functions as a useful anesthetic, although it alters some blood biochemical parameters. In this study, we examined the effects of this mixture on anesthesia and blood biochemical parameters, and the action of atipamezole, a medetomidine antagonist, in hamsters. Intramuscular injection of a mixture of medetomidine, midazolam and butorphanol at doses of 0...
July 19, 2017: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/28599888/cardiopulmonary-effects-of-pleural-insufflation-with-co2-during-two-lung-ventilation-in-dorsally-recumbent-anesthetized-horses
#18
Kaylee S Bohaychuk-Preuss, M Valentina Carrozzo, Tanya Duke-Novakovski
OBJECTIVE: To record the cardiopulmonary effects of pleural CO2 positive pressure insufflation in anesthetized horses. STUDY DESIGN: Prospective study. ANIMALS: Seven horses (mean ± standard deviation, 530.9 ± 68.1 kg) undergoing terminal surgery. METHODS: Horses were sedated with xylazine. Anesthesia was induced with ketamine-propofol and maintained with isoflurane, positive pressure ventilation, detomidine infusion, and butorphanol with the horses in dorsal recumbency...
January 10, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28579821/opioid-analgesics-related-pharmacokinetic-drug-interactions-from-the-perspectives-of-evidence-based-on-randomized-controlled-trials-and-clinical-risk-management
#19
REVIEW
Xiu-Qin Feng, Ling-Ling Zhu, Quan Zhou
BACKGROUND: Multimorbidity results in complex polypharmacy which may bear a risk of drug interactions. A better understanding of opioid analgesics combination therapy used for pain management could help warrant medication safety, efficacy, and economic relevance. Until now there has been no review summarizing the opioid analgesics-related pharmacokinetic drug interactions from the perspective of evidence based on randomized controlled trials (RCTs). METHOD: A literature search was performed using PubMed, MEDLINE, and the Cochrane Library, using a PRISMA flowchart...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28548551/comparison-of-intramuscular-butorphanol-and-buprenorphine-combined-with-dexmedetomidine-for-sedation-in-cats
#20
Rebecca J Bhalla, Toby A Trimble, Elizabeth A Leece, Enzo Vettorato
Objectives The objective of this study was to compare the sedative effect of butorphanol-dexmedetomidine with buprenorphine-dexmedetomidine following intramuscular (IM) administration in cats. Methods Using a prospective, randomised, blinded design, 40 client-owned adult cats were assigned to receive IM dexmedetomidine (10 µg/kg) combined with either butorphanol (0.4 mg/kg) ('BUT' group) or buprenorphine (20 µg/kg) ('BUP' group). Sedation was scored using a previously published multidimensional composite scale before administration (T0) and 5, 10, 15 and 20 mins afterwards (T5, T10, T15 and T20, respectively)...
May 1, 2017: Journal of Feline Medicine and Surgery
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