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https://www.readbyqxmd.com/read/29165006/effect-of-non-steroidal-anti-inflammatory-drugs-on-postoperative-respiratory-and-heart-rate-in-cats-subjected-to-ovariohysterectomy
#1
Odd V Höglund, Barbara Dyall, Victoria Gräsman, Anna Edner, Ulf Olsson, Katja Höglund
Objectives The use of physiological parameters such as respiratory rate and heart rate to assess pain has long been discussed. The aim of the study was to compare postoperative respiratory rate and heart rate in cats subjected to flank ovariohysterectomy treated with a preoperative non-steroidal anti-inflammatory drug (NSAID) or no NSAID, and determine whether these parameters are suitable for postoperative pain assessment in cats. We hypothesised that cats without an NSAID would experience more postoperative pain, which may increase heart rate and respiratory rate...
November 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/29153109/non-invasive-blood-pressure-measurement-in-ferrets-mustela-putorius-furo-using-high-definition-oscillometry
#2
Y R A van Zeeland, A Wilde, I H Bosman, J J Uilenreef, B Egner, N J Schoemaker
This study was conducted to validate the use of high definition oscillometry (HDO) for non-invasive blood pressure (NIBP) measurements in ferrets and to establish reference ranges for NIBP in minimally sedated, healthy, young adult ferrets (<4years of age). The bias, limits of agreement and correlation for HDO compared to direct arterial blood pressure (DABP) measurement were established in 14 anaesthetised ferrets. Measurements were performed at the forelimb, hind limb and tail under hypo- (<110mmHg), normo- (110-170mmHg) and hypertensive (>170mmHg) conditions...
October 2017: Veterinary Journal
https://www.readbyqxmd.com/read/29057764/evaluation-of-total-intravenous-anesthesia-with-propofol-guaifenesin-medetomidine-and-alfaxalone-guaifenesin-medetomidine-in-thoroughbred-horses-undergoing-castration
#3
Motoki Aoki, Ai Wakuno, Asuka Kushiro, Naomi Mae, Masashi Kakizaki, Shun-Ichi Nagata, Minoru Ohta
Anesthetic and cardiorespiratory effects of total intravenous anesthesia (TIVA) technique using propofol-guaifenesin-medetomidine (PGM) and alfaxalone-guaifenesin-medetomidine (AGM) were preliminarily evaluated in Thoroughbred horses undergoing castration. Twelve male Thoroughbred horses were assigned randomly into two groups. After premedication with intravenous (IV) administrations of medetomidine (5.0 μg/kg) and butorphanol (0.02 mg/kg), anesthesia was induced with guaifenesin (10 mg/kg IV), followed by either propofol (2...
October 23, 2017: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/29051000/pulsed-inhaled-nitric-oxide-improves-arterial-oxygenation-in-colic-horses-undergoing-abdominal-surgery
#4
Maja Wiklund, Izabella Granswed, Görel Nyman
OBJECTIVE: To evaluate the effect of pulsed inhaled nitric oxide (INO) on arterial oxygenation in horses during abdominal surgery. STUDY DESIGN: Prospective, randomized, clinical trial. ANIMALS: Thirty horses that underwent abdominal surgery at the University Animal Hospital in Uppsala, Sweden. METHODS: Anaesthesia was induced according to a standard protocol - romifidine, butorphanol, diazepam and ketamine and maintained with isoflurane in oxygen...
April 17, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28955163/anesthetic-management-with-sevoflurane-combined-with-alfaxalone-medetomidine-constant-rate-infusion-in-a-thoroughbred-racehorse-undergoing-a-long-time-orthopedic-surgery
#5
Ai Wakuno, Tatsuya Maeda, Kazumichi Kodaira, Takuya Kikuchi, Minoru Ohta
A three-year old Thoroughbred racehorse was anesthetized with sevoflurane and oxygen inhalation anesthesia combined with constant rate infusion (CRI) of alfaxalone-medetomidine for internal fixation of a third metacarpal bone fracture. After premedication with intravenous (IV) injections of medetomidine (6.0 µg/kg IV), butorphanol (25 µg/kg IV), and midazolam (20 µg/kg IV), anesthesia was induced with 5% guaifenesin (500 ml/head IV) followed immediately by alfaxalone (1.0 mg/kg IV). Anesthesia was maintained with sevoflurane and CRIs of alfaxalone (1...
2017: Journal of Equine Science
https://www.readbyqxmd.com/read/28948901/evaluation-of-an-intramuscular-butorphanol-and-alfaxalone-protocol-for-feline-blood-donation-a-pilot-study
#6
Marcella C Granfone, Julie M Walker, Lesley J Smith
Objectives The purpose of this pilot study was to evaluate the use of an intramuscular (IM) sedation protocol with butorphanol and alfaxalone in cats undergoing blood donation. We hypothesized that this drug combination would provide sufficient sedation to perform phlebotomy without causing hypotension or significant changes in heart rate. Methods Six purpose-bred, healthy adult cats were sedated using IM butorphanol (0.4 mg/kg) and alfaxalone (2-3 mg/kg). Pulse and Doppler blood pressure (BP) were recorded at baseline, after sedation and immediately following phlebotomy...
September 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28948896/anaesthesia-and-changes-in-parameters-that-reflect-glucose-metabolism-in-pigs-a-pilot-study
#7
Elin Manell, Marianne Jensen-Waern, Patricia Hedenqvist
Pigs are commonly used in diabetes research due to their many physiological similarities to humans. They are especially useful in imaging procedures because of their large size. However, to achieve imaging procedures the pig must lie completely still, and thus needs to be anaesthetized. Most anaesthetic drugs used in laboratory animals affect carbohydrate metabolism by the inhibition of insulin release. The aim of this pilot study was primarily to develop an anaesthetic protocol for pigs that did not have an effect on blood glucose levels throughout the 3 h of anaesthesia; and secondly, to evaluate the most promising protocol in combination with an oral glucose tolerance test (OGTT)...
October 2017: Laboratory Animals
https://www.readbyqxmd.com/read/28922361/impact-of-four-different-recumbencies-on-the-distribution-of-ventilation-in-conscious-or-anaesthetized-spontaneously-breathing-beagle-dogs-an-electrical-impedance-tomography-study
#8
Tamas D Ambrisko, Johannes P Schramel, Ulrike Auer, Yves P S Moens
The aim was to examine the effects of recumbency and anaesthesia on distribution of ventilation in beagle dogs using Electrical Impedance Tomography (EIT). Nine healthy beagle dogs, aging 3.7±1.7 (mean±SD) years and weighing 16.3±1.6 kg, received a series of treatments in a fixed order on a single occasion. Conscious dogs were positioned in right lateral recumbency (RLR) and equipped with 32 EIT electrodes around the thorax. Following five minutes of equilibration, two minutes of EIT recordings were made in each recumbency in the following order: RLR, dorsal (DR), left (LLR) and sternal (SR)...
2017: PloS One
https://www.readbyqxmd.com/read/28920785/detomidine-and-butorphanol-for-standing-sedation-in-a-range-of-zoo-kept-ungulate-species
#9
Tim Bouts, Joanne Dodds, Karla Berry, Abdi Arif, Polly Taylor, Andrew Routh, Frank Gasthuys
General anesthesia poses risks for larger zoo species, like cardiorespiratory depression, myopathy, and hyperthermia. In ruminants, ruminal bloat and regurgitation of rumen contents with potential aspiration pneumonia are added risks. Thus, the use of sedation to perform minor procedures is justified in zoo animals. A combination of detomidine and butorphanol has been routinely used in domestic animals. This drug combination, administered by remote intramuscular injection, can also be applied for standing sedation in a range of zoo animals, allowing a number of minor procedures...
September 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28865107/effect-of-body-position-exercise-and-sedation-on-estimation-of-pulmonary-artery-pressure-in-dogs-with-degenerative-atrioventricular-valve-disease
#10
J D Rhinehart, K E Schober, B A Scansen, V Yildiz, J D Bonagura
BACKGROUND: Severity of pulmonary hypertension (PH) in dogs is related to clinical signs and prognosis. HYPOTHESIS/OBJECTIVES: We hypothesized that Doppler echocardiographic (DE) indices of pulmonary artery pressure (PAP) and pulmonary vascular resistance (PVR) are influenced by independent factors that create clinically important variability of DE-based estimates of PH in dogs. ANIMALS: Thirty-eight client owned dogs with naturally acquired degenerative atrioventricular valve disease and tricuspid regurgitation (TR)...
September 2, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28836839/antinociceptive-efficacy-of-intramuscular-administration-of-morphine-sulfate-and-butorphanol-tartrate-in-tegus-salvator-merianae
#11
William P Leal, Adriano B Carregaro, Thais F Bressan, Shayne P Bisetto, Cristiano F Melo, Kurt K Sladky
OBJECTIVE To evaluate the antinociceptive efficacy of IM morphine sulfate or butorphanol tartrate administration in tegus (Salvator merianae). ANIMALS 6 healthy juvenile (12- to 24-month-old) tegus (mean ± SD body weight, 1,484 ± 473 g). PROCEDURES In a crossover study design, tegus were randomly assigned to treatment order, with a minimum washout period of 15 days between treatments. Each of 5 treatments was administered IM in a forelimb: saline (0.9% NaCl) solution (0.5 mL), morphine sulfate (5 or 10 mg/kg), or butorphanol tartrate (5 or 10 mg/kg)...
September 2017: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/28828865/comparison-of-thiafentanil-medetomidine-to-etorphine-medetomidine-immobilisation-of-impalas-i-aepyceros-melampus-i
#12
Gareth E Zeiler, Leith C R Meyer
Impalas (Aepyceros melampus) are increasingly valuable in the South African wildlife industry, and there is a greater need to chemically immobilise them, ideally with minimal risk. This study aimed to compare the times to recumbency and physiological effects of thiafentanilmedetomidine versus etorphine-medetomidine immobilisation. A combination of thiafentanil (2 mg) + medetomidine (2.2 mg) and etorphine (2 mg) + medetomidine (2.2 mg) was administered (to nine impalas; crossover design) via a dart. After darting, a stopwatch was started to record times to recumbency (time from darting until recumbent without attempts to stand)...
August 4, 2017: Journal of the South African Veterinary Association
https://www.readbyqxmd.com/read/28822974/sedative-and-cardiopulmonary-effects-of-dexmedetomidine-infusions-randomly-receiving-or-not-butorphanol-in-standing-horses
#13
RANDOMIZED CONTROLLED TRIAL
Luíza Quintão Medeiros, Miguel Gozalo-Marcilla, Polly M Taylor, Daniela Campagnol, Flávia Augusta de Oliveira, Marcos Jun Watanabe, Antonio José de Araujo Aguiar
Dexmedetomidine (DEX) alone, or combined with butorphanol (BUT), may be administered by constant rate infusions (CRIs) in standing horses. This blinded, randomised, crossover study in six healthy adult horses aimed to determine the sedative and cardiopulmonary effects of DEX (dexmedetomidine (3.5 µg/kg+5 µg/kg/hour CRI) and DEX/BUT (dexmedetomidine (3.5 µg/kg+3.5 µg/kg/hour CRI) and butorphanol (20 µg/kg+24 µg/kg/hour CRI)). Head height above ground (HHAG), ataxia, responses to tactile/auditory stimuli and cardiopulmonary variables were recorded before, at 5/15/30/60/90 minutes and after CRIs terminated (15/30/60 minutes)...
October 14, 2017: Veterinary Record
https://www.readbyqxmd.com/read/28796153/optimum-drug-combinations-for-the-sedation-of-growing-boars-prior-to-castration
#14
Heidi S Lehmann, Dominique Blache, Eleanor Drynan, Pema Tshewang, David J C Blignaut, Gabrielle C Musk
Juvenile male pigs were sedated for castration. Eight five-month old boars were sedated twice (two weeks apart) with a combination of detomidine (0.1 mg/kg), midazolam (0.2 mg/kg) and either butorphanol (0.2 mg/kg) (Group MDB, n = 8) or morphine (0.2 mg/kg) (Group MDM, n = 8) intramuscularly. The boars were positioned in lateral recumbency and lidocaine (200 mg total) was injected into the testicle and scrotal skin. Castration of a single testicle was performed on two occasions. Sedation and reaction (to positioning and surgery) scores, pulse rate, respiratory rate, haemoglobin oxygen saturation, body temperature, arterial blood gas parameters and the times to immobility and then recovery were recorded...
August 10, 2017: Animals: An Open Access Journal From MDPI
https://www.readbyqxmd.com/read/28765033/assessment-of-butorphanol-azaperone-medetomidine-combination-as-anesthesia-for-semen-collection-and-evaluation-of-semen-quality-in-white-tailed-deer-odocoileus-virginianus
#15
S M Kirschner, R Rodenkirch
The aim of this current study was to evaluate the level of anesthesia produced by a combination of butorphanol-azaperone-medetomidine (BAM) for semen collection by electroejaculation on captive white-tailed bucks (Odocoileus virginianus). Ten male white-tailed deer, weighing 68.2-115.9kg, ranging in age from one to four years were randomly selected from housing pens and anesthetized with the BAM drug combination at a dose volume of 2.0mL each. Semen was collected from each animal using a standard cervid electroejaculation protocol while under BAM anesthesia...
July 25, 2017: Animal Reproduction Science
https://www.readbyqxmd.com/read/28738000/comparison-of-cardiac-output-measured-by-use-of-computed-tomography-and-thermodilution-in-dogs
#16
Sharon Tenenbaum, Fernando L Garcia-Pereira, Clifford R Berry, Tori Obert
OBJECTIVE To compare cardiac output (CO) measured by use of CT coronary angiography and thermodilution (criterion-referenced standard) at various CO values, record adverse effects, and determine the time needed to measure CO. ANIMALS 5 healthy purpose-bred Beagles (2 males and 3 females). PROCEDURES A prospective nonrandomized crossover study was conducted. Dogs were premedicated with butorphanol tartrate (0.2 mg•kg(-1), IM). Anesthesia was induced by IV administration of etomidate (1 to 2 mg•kg(-1)) and midazolam (0...
August 2017: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/28717545/low-dose-lignocaine-butorphanol-vs-low-dose-bupivacaine-for-spinal-anaesthesia-in-day-care-urological-surgeries-a-prospective-randomized-control-trial
#17
Shahil Rameshbhai Khant, Rajeev Chaudhari, Rishikesh Arun Kore, Shirish Bhagwat, Ranjan Purushottam Jakhalekar
OBJECTIVE: A local anaesthetic with fast onset, short and reliable duration of anaesthesia may be preferable for day care urological surgeries. Low dose lignocaine is believed to act faster and to have a shorter duration of action than low dose bupivacaine. Use of lignocaine for spinal anesthesia is discouraged now a days because of rare reports of transient neurological symptoms. The purpose of this study was to compare effectiveness and safety of low dose of lignocaine + butorphanol against low dose of bupivacaine for day care urological surgeries...
June 2017: Turkish Journal of Urology
https://www.readbyqxmd.com/read/28716685/the-use-of-alfaxalone-for-premedication-induction-and-maintenance-of-anaesthesia-in-pigs-a-pilot-study
#18
Sarah E Bigby, Jennifer E Carter, Sébastien Bauquier, Thierry Beths
OBJECTIVE: The evaluation of alfaxalone as a premedication agent and intravenous anaesthetic in pigs. STUDY DESIGN: Prospective, clinical trial. ANIMALS: Nine healthy, 6-8-week-old female Landrace pigs weighing 22.2 ± 1.0 kg, undergoing epidural catheter placement. METHODS: All pigs were premedicated with 4 mg kg(-1) alfaxalone, 40 μg kg(-1) medetomidine and 0.4 mg kg(-1) butorphanol administered in the cervical musculature...
March 21, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28687474/alfaxalone-for-maintenance-of-anaesthesia-in-ponies-undergoing-field-castration-continuous-infusion-compared-with-intravenous-boluses
#19
Julia Deutsch, Abel Ekiri, Annemarie de Vries
OBJECTIVE: To compare alfaxalone as continuous intravenous (IV) infusion with intermittent IV injections for maintenance of anaesthesia in ponies undergoing castration. STUDY DESIGN: Prospective, randomized, 'blinded' clinical study. ANIMALS: A group of 33 entire male Welsh ponies undergoing field castration. METHODS: After preanaesthetic medication with IV detomidine (10 μg kg(-1)) and butorphanol (0.05 mg kg(-1)), anaesthesia was induced with IV diazepam (0...
April 14, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28684240/intramuscular-injection-of-alfaxalone-in-combination-with-butorphanol-for-sedation-in-cats
#20
Julia Deutsch, Colette Jolliffe, Emma Archer, Elizabeth A Leece
OBJECTIVE: To assess quality of sedation following intramuscular (IM) injection of two doses of alfaxalone in combination with butorphanol in cats. STUDY DESIGN: Prospective, randomized, 'blinded' clinical study. ANIMALS: A total of 38 cats undergoing diagnostic imaging or noninvasive procedures. METHODS: Cats were allocated randomly to be administered butorphanol 0.2 mg kg(-1) combined with alfaxalone 2 mg kg(-1) (group AB2) or 5 mg kg(-1) (group AB5) IM...
March 6, 2017: Veterinary Anaesthesia and Analgesia
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