Phattarawadee Wattanasuntorn, Patchara Phuktes, Saranya Poapolathep, Sontana Mimapan, Muncharee Tattiyapong, Johanna Fink-Gremmels, Isabelle P Oswald, Amnart Poapolathep
Mycotoxins are toxic, fungal secondary metabolites that contaminate agricultural commodities, food, and feed. Among them, T-2, HT-2, and diacetoxyscirpenol (DAS; the major type A trichothecene) are primarily produced from Fusarium species. These mycotoxins exert numerous toxicological effects in animals and humans, such as dermatotoxicity, haematotoxicity, hepatotoxicity, nephrotoxicity, neurotoxicity, and immunotoxicity. In the present study, human Jurkat T cells were used as a model to investigate apoptotic cell death induced by T-2, HT-2, and DAS...
April 11, 2024: Toxicon: Official Journal of the International Society on Toxinology