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https://www.readbyqxmd.com/read/27922984/osteochondral-allografts-in-shoulder-surgical-procedures
#1
Nicholas M Capito, Brett D Owens, Seth L Sherman, Matthew J Smith
No abstract text is available yet for this article.
November 15, 2016: JBJS Reviews
https://www.readbyqxmd.com/read/27919119/-osteochondritis-dissecans-of-the-talus-a-critical-review
#2
J Bruns, C R Habermann, J P Petersen
The etiology remains unclear. Mechanical factors seem to play an important role. Most histologies report clefts between the cartilage and bone and necrotic areas. Several classifications have been published based on observations from imaging techniques or on intraoperative findings. Clinical symptoms are unspecific. Imaging techniques are of great importance: X-rays of the ankle joint enable a quick diagnostic overview. MRT is the imaging-technique of choice for diagnosing OCDT-lesions. Regarding treatment, a tremendous number of retrospective publications exist...
April 2016: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/27912680/biomimetic-approaches-for-bone-tissue-engineering
#3
Johnathan Ng, Kara Spiller, Jonathan Bernhard, Gordana Vunjak-Novakovic
Although autologous bone grafts are considered a gold standard for the treatment of bone defects, they are limited by donor site morbidities and geometric requirements. Tissue engineering can overcome such limitations by creating fully viable biological bone grafts. We review here the use of native bone matrix, autologous mesenchymal cells and perfusion bioreactor systems as a tissue-engineering paradigm to grow bone in vitro. We also discuss emergent vascularization strategies to promote graft survival in vivo, and the role of inflammation in bone repair...
December 2, 2016: Tissue Engineering. Part B, Reviews
https://www.readbyqxmd.com/read/27910738/cartilage-repair-in-the-degenerative-ageing-knee
#4
Mats Brittberg, Andreas H Gomoll, José A Canseco, Jack Far, Martin Lind, James Hui
Background and purpose - Cartilage damage can develop due to trauma, resulting in focal chondral or osteochondral defects, or as more diffuse loss of cartilage in a generalized organ disease such as osteoarthritis. A loss of cartilage function and quality is also seen with increasing age. There is a spectrum of diseases ranging from focal cartilage defects with healthy surrounding cartilage to focal lesions in degenerative cartilage, to multiple and diffuse lesions in osteoarthritic cartilage. At the recent Aarhus Regenerative Orthopaedics Symposium (AROS) 2015, regenerative challenges in an ageing population were discussed by clinicians and basic scientists...
December 2, 2016: Acta Orthopaedica
https://www.readbyqxmd.com/read/27909662/osteochondral-autograft-transfer-technique-for-glenoid-osteochondral-defect
#5
Douglas J Wyland, Clint Beicker
Glenoid osteochondral defects can be a significant source of pain and disability in an active population. Many treatments are available, but most joint-preserving procedures are limited to debridement, abrasion chondroplasty, or marrow-stimulation techniques, all of which depend on healthy underlying bone and none of which address underlying bony pathology. Osteochondral autograft transfer has been a successful form of treatment for lesions in the knee, elbow, and ankle, especially when subchondral bone is involved...
October 2016: Arthroscopy Techniques
https://www.readbyqxmd.com/read/27909660/osteochondral-proximal-tibial-and-lateral-meniscal-allograft-transplant
#6
Guillem Gonzalez-Lomas, Andrew P Dold, Daniel J Kaplan, David J Fralinger, Laith Jazrawi
Knee pain in young, active patients with meniscus-deficient knees and articular cartilage damage can present a challenge to treatment. Meniscal allograft transplantation (MAT) has shown good clinical results as treatment for meniscus deficiency; however, worse outcomes have been observed in patients with significant chondral damage. The development of chondral restorative techniques such as osteochondral allograft transplantation (OCA) has expanded the population of patients who may benefit from MAT. We present a case of proximal tibial osteochondral and lateral meniscal allograft transplant...
October 2016: Arthroscopy Techniques
https://www.readbyqxmd.com/read/27906096/biological-and-functional-evaluation-of-a-novel-pyrolytic-carbon-implant-for-the-treatment-of-focal-osteochondral-defects-in-the-medial-femoral-condyle-assessment-in-a-canine-model
#7
Samantha L Salkeld, Laura P Patron, Joan C Lien, Stephen D Cook, Deryk G Jones
BACKGROUND: Osteochondral defects continue to be a clinical treatment challenge, and when left untreated, may cause pain and functional impairment. Pyrolytic carbon is a unique isotropic biomaterial used in heart valve and small joint replacements due to its excellent wear properties and biocompatibility with bone and articular cartilage. Therefore, a proposed solution is to utilize a focal pyrolytic carbon hemiarthroplasty implant as an alternative resurfacing treatment strategy for isolated cartilage lesions...
December 1, 2016: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/27904793/current-concepts-in-treatment-of-patellofemoral-osteochondritis-dissecans
#8
Chris Juneau, Russ Paine, Eric Chicas, Emily Gardner, Lane Bailey, James McDermott
: Identification, protection, and management of patellofemoral articular cartilage lesions continue to remain on the forefront of sports medicine rehabilitation. Due to high-level compression forces that are applied through the patellofemoral (PF) joint, managing articular cartilage lesions is challenging for sports medicine specialists. Articular cartilage damage may exist in a wide spectrum of injuries ranging from small, single areas of focal damage to wide spread osteoarthritis involving large chondral regions...
December 2016: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/27900309/from-loose-body-to-osteochondritis-dissecans-a-historical-account-of-disease-definition
#9
Vittorio Tarabella, Giuseppe Filardo, Berardo DI Matteo, Luca Andriolo, Patrizia Tomba, Anna Viganò, Maurilio Marcacci
Osteochondritis dissecans (OCD) is a rare yet fascinating disease affecting young, active patients. It remains a 'mysterious disease' whose etiopathology, still unclear, is the subject of ongoing studies aiming improving the knowledge of this condition and, therefore, treatment options, too. Even though the first descriptions of intra-articular loose bodies date back to very ancient times, it is only relatively recently that, thanks to the contribution of some very eminent physicians, it became recognized as a specific orthopaedic condition...
July 2016: Joints
https://www.readbyqxmd.com/read/27896291/fresh-osteochondral-allograft-to-the-humeral-head-for-treatment-of-an-engaging-reverse-hill-sachs-lesion-technical-case-report-and-literature-review
#10
Loren O Black, Jia-Wei Kevin Ko, Samantha M Quilici, Dennis C Crawford
No abstract text is available yet for this article.
November 2016: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/27893924/deciding-how-best-to-treat-cartilage-defects
#11
Lucy Oliver-Welsh, Justin W Griffin, Maximilian A Meyer, Matthew E Gitelis, Brian J Cole
The decision-making regarding and treatment of cartilage abnormalities requires a systematic approach. This article reviews the concepts and principles that guide the management of this complex problem. The precise incidence, demographics, and progression of cartilage lesions have not been clearly delineated. Pursuing a patient-centered approach that considers the available nonsurgical and surgical options remains the cornerstone of patient care. The importance of determining concomitant knee pathologies, the proper interpretation and implications of imaging findings, and an accurate determination of the intra-articular and subchondral findings represent the primary elements of the decision analysis...
November 1, 2016: Orthopedics
https://www.readbyqxmd.com/read/27892651/fumarate-copolymer-chitosan-cross-linked-scaffold-directed-to-osteochondrogenic-tissue-engineering
#12
María Laura Lastra, María Silvina Molinuevo, Ana María Cortizo, María Susana Cortizo
Natural and synthetic cross-linked polymers allow the improvement of cytocompatibility and mechanical properties of the individual polymers. In osteochondral lesions of big size it will be required the use of scaffolds to repair the lesion. In this work a borax cross-linked scaffold based on fumarate-vinyl acetate copolymer and chitosan directed to osteochondrondral tissue engineering is developed. The cross-linked scaffolds and physical blends of the polymers are analyzed in based on their morphology, glass transition temperature, and mechanical properties...
November 28, 2016: Macromolecular Bioscience
https://www.readbyqxmd.com/read/27891511/diagnostic-value-of-ct-arthrography-for-evaluation-of-osteochondral-lesions-at-the-ankle
#13
Jan S Kirschke, Sepp Braun, Thomas Baum, Christian Holwein, Christoph Schaeffeler, Andreas B Imhoff, Ernst J Rummeny, Klaus Woertler, Pia M Jungmann
Background. To retrospectively determine the diagnostic value of computed tomography arthrography (CTA) of the ankle in the evaluation of (osteo)chondral lesions in comparison to conventional magnetic resonance imaging (MRI) and intraoperative findings. Methods. A total of N = 79 patients had CTAs and MRI of the ankle; in 17/79 cases surgical reports with statements on cartilage integrity were available. Cartilage lesions and bony defects at talus and tibia were scored according to defect depth and size by two radiologists...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27886685/posterior-malleolus-fractures
#14
REVIEW
Shay Tenenbaum, Nachshon Shazar, Nathan Bruck, Jason Bariteau
Posterior malleolus fractures vary in morphology. A computed tomography scan is imperative to evaluate fragment size, comminution, articular impaction, and syndesmotic disruption. Despite an increasing body of literature regarding posterior malleolus fractures, many questions remain unanswered. Although, historically, fragment size guided surgical fixation, it is becoming evident that fragment size should not solely dictate treatment. Surgical treatment should focus on restoring ankle joint structural integrity, which includes restoring articular congruity, correcting posterior talar translation, addressing articular impaction, removing osteochondral debris, and establishing syndesmotic stability...
January 2017: Orthopedic Clinics of North America
https://www.readbyqxmd.com/read/27871420/platelet-rich-plasma-and-concentrated-bone-marrow-aspirate-in-surgical-treatment-for-osteochondral-lesions-of-the-talus
#15
REVIEW
Youichi Yasui, Andrew W Ross, John G Kennedy
Platelet-rich plasma (PRP) and concentrated bone marrow aspirate (CBMA) have the potential to improve the quality of cartilage repair in osteochondral lesions of the talus (OLT). In this review, we describe the basic science and clinical evidence that has been published on the topic of PRP and CBMA on 2 commonly used surgical techniques for the treatment of OLT: bone marrow stimulation and osteochondral autograft transfer.
December 2016: Foot and Ankle Clinics
https://www.readbyqxmd.com/read/27871417/large-bm-intra-articular-allograft
#16
REVIEW
Joan R Williams, Michael E Brage
Posttraumatic tibiotalar arthritis is a challenging problem in young, active patients. Many of these patients do not want to pursue ankle arthrodesis after they fail conservative treatment measures, as they wish to preserve joint motion. Osteochondral shell allograft arthroplasty has been described as a reasonable alternative for treating these patients. The procedure itself is technically demanding; however, with improvements in surgical technique and adequate preoperative patient counseling, it provides improvement in ankle function and has good outcomes for most patients at long-term follow-up...
December 2016: Foot and Ankle Clinics
https://www.readbyqxmd.com/read/27863947/the-effects-of-low-dose-radiotherapy-on-fresh-osteochondral-allografts-an-experimental-study-in-rabbits
#17
Uğur Gönç, Mehmet Çetinkaya, Mesut Atabek
OBJECTIVE: The aim of this study was to investigate the effects of low-dose fractionated radiotherapy on cartilage degeneration after distal femoral fresh massive osteochondral allograft transplantation. METHODS: Twenty-four New Zealand White rabbits were divided into three groups of 8 rabbits each. All rabbits underwent distal femoral medial condyle fresh massive osteochondral allograft transplantation from California rabbits. The group 1 underwent transplantation without any preliminary process...
November 15, 2016: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/27859554/evaluation-of-genipin-for-stabilization-of-decellularized-porcine-cartilage
#18
Steven Elder, Amanda Pinheiro, Christian Young, Preston Smith, Emily Wright
We speculate that an acellular osteochondral xenograft may be a good alternative to allografts for repair of focal articular cartilage lesions. In order to make a xenograft resistant to enzymatic degradation and to prevent a chronic immune response it may beneficial to stabilize it through crosslinking. The concept is analogous to treatment of porcine bioprosthetic heart valves with glutaraldehyde. The purpose of this study was to evaluate genipin, a natural crosslinking agent with low cytotoxicity, for stabilization of decellularized cartilage...
November 18, 2016: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/27852595/lesion-size-is-a-predictor-of-clinical-outcomes-after-bone-marrow-stimulation-for-osteochondral-lesions-of-the-talus-a-systematic-review
#19
Laura Ramponi, Youichi Yasui, Christopher D Murawski, Richard D Ferkel, Christopher W DiGiovanni, Gino M M J Kerkhoffs, James D F Calder, Masato Takao, Francesca Vannini, Woo Jin Choi, Jin Woo Lee, James Stone, John G Kennedy
BACKGROUND: The critical lesion size treated with bone marrow stimulation (BMS) for osteochondral lesions of the talus (OLTs) has been 150 mm(2) in area or 15 mm in diameter. However, recent investigations have failed to detect a significant correlation between the lesion size and clinical outcomes after BMS for OLTs. PURPOSE: To systematically review clinical studies reporting both the lesion size and clinical outcomes after BMS for OLTs. STUDY DESIGN: Systematic review...
November 16, 2016: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/27845285/-clinical-significance-of-biomarkers-of-osteochondral-lesions-in-early-rheumatoid-arthritis
#20
D Rekalov
The aim of the research was to study biomarkers of osteochondral lesions on early stages of rheumatoid arthritis (RA). The data showed the prognostic value of indicators of the erosive and destructive changes of joints in early and in the advanced stage of RA. Indicators that determine how directly, inflammatory process activity and markers associated with the speed and staging damage of articular surfaces is analyzed. That can adequately justify individualized clinical strategy in patients with early RA.
October 2016: Georgian Medical News
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