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osteochondritis dissecans

Alan Danielski, Michael Farrell
CASE DESCRIPTION:  An 8-month-old American Bulldog was presented for assessment of bilateral thoracic limb lameness. Computed tomographic imaging revealed large, deep osteochondritis dissecans lesions in both humeral heads. TREATMENT AND OUTCOME:  The osteochondritis dissecans lesions were debrided and the exposed subchondral defects were prepared to receive synthetic grafts. Circular implants consisting of a surface layer of polycarbonate urethane and a deep layer of lattice-type titanium were implanted into the osteochondral defects to reconstruct the articular surface topography...
June 20, 2018: Veterinary and Comparative Orthopaedics and Traumatology: V.C.O.T
L Chadli, C Steltzlen, P Beaufils, C Toanen, N Pujol
PURPOSE: The goal of the fixation of painful osteochondritis dissecans of the femoral condyles in adults is to integrate the osteochondral fragment and thus achieve a normal hyaline cartilaginous coverage. The addition of a biological process to primary fixation may result in improved fragment integration (hybrid fixation). Osteochondral plugs may fulfil this role. The aim of this study was to evaluate long-term clinical and radiological results after hybrid fixation of unstable osteochondritis dissecans...
June 19, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
Deepak Kumar Sharma, Narendra Kumar, Hitesh Lal, Binay Kumar Sahu, Sumon Singphow Saikia
Osteochondritis dissecans is a common disorder of knee and can be treated by various methods, depending on age of patient and stability of chondral fragment. In Osteochondritis dissecans ICRS type III lesion i.e. articular cartilage discontinuity but no dislocation, variable rate of union as well as high rate of non-union was observed in previous studies when treated with arthroscopic or open reduction and fixation. In previous study it has been also shown that platelet rich plasma help in fracture healing...
April 2018: Journal of Clinical Orthopaedics and Trauma
Mitsuaki Kubota, Muneaki Ishijima, Hiroshi Ikeda, Yuji Takazawa, Yoshitomo Saita, Haruka Kaneko, Hisashi Kurosawa, Kazuo Kaneko
Objective: To assess the longitudinal outcomes of osteochondritis dissecans (OCD) fixation and to detect the influencing factor for the results of OCD. Methods: 22 OCD fixation using bioabsorbable pins were assessed Lysholm score, Tegner activity scale and KOOS4 at preoperative, postoperative short (3.0 years) and mid-long (11.9 years) term. Results: Postoperative Lysholm score was significantly better than the preoperative time. There was no factor influencing KOOS4 at mid-long term...
June 2018: Journal of Orthopaedics
Kazuki Sato, Takuji Iwamoto, Noboru Matsumura, Taku Suzuki, Yuji Nishiwaki, Yoshinori Oka, Toshiyasu Nakamura
BACKGROUND: Costal osteochondral grafting is a technique to achieve anatomical and biological repair of articular defects. Some small series of clinical applications of this procedure for advanced osteochondritis dissecans of the humeral capitellum, with short-term follow-up, have been reported; however, longer-term outcomes remain unclear. The purpose of this study was to clarify longer-term clinical outcomes of costal osteochondral autografts in the treatment of advanced osteochondritis dissecans of the humeral capitellum...
June 6, 2018: Journal of Bone and Joint Surgery. American Volume
Soshi Uchida, Yuki Shimizu, Yohei Yukizawa, Hitoshi Suzuki, Cecilia Pascual-Garrido, Akinori Sakai
Intra-articular lesions are common in patients with acetabular hip dysplasia. Rim stress fractures (RSFs) have also been described in patients with acetabular hip dysplasia. This lesion is believed to be a result of an unfused secondary ossification center or a stress fracture that could be caused by repetitive impingement of an abnormal-shaped femoral head-neck junction. In addition, osteochondritis dissecans of the acetabulum is a rare condition that can also result from impingement and has been described in patients with hip dysplasia...
May 2018: Arthroscopy Techniques
David R Maldonado, Brian H Mu, Austin W Chen, Victor Ortiz-Declet, Itay Perets, Leslie C Yuen, Benjamin G Domb
Treatment options for the management of osteochondritis dissecans (OCD) lesions of the femoral head are limited. Although arthroscopic surgery of the hip can treat a variety of intra- and extra-articular pathologies, an OCD lesion located at the superior and medial zone of the femoral head is often difficult to access and cannot be adequately treated arthroscopically. The use of fresh-stored osteochondral allograft allows surgeons to both avoid donor-site morbidity and treat lesions of a larger surface area...
April 2018: Arthroscopy Techniques
Elina Ekman, Keijo Mäkelä, Ia Kohonen, Ari Hiltunen, Ari Itälä
PURPOSE: The aim of this study was to assess the progression of radiological cartilage changes and to document the functional, long-term results during a follow-up of 10 years after osteoautograft transplantation (OAT) knee surgery. METHODS: The study was a retrospective analysis of all patients who underwent OAT at Turku University Hospital from 1999 to 2007. Pre- and postoperative cartilage changes were estimated based on standardised radiographs. The extent of osteoarthritis (OA) was graded according to the Kellgren-Lawrence scale...
June 2, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
Lucie Biehler-Gomez, Elisa Castoldi, Elisa Baldini, Annalisa Cappella, Cristina Cattaneo
Diabetes mellitus is a condition with severe and life-threatening complications and epidemic proportions worldwide. The study of diabetes on bones can provide crucial information to the forensic practice, the archeological field and medical research. In this paper, the authors report and discuss the lesions observed on the skeletons of 38 individuals (plus 11 negative control samples) of the CAL Milano Cemetery Skeletal Collection with known diabetes. As a result, different types of lesions were highlighted in the feet: periosteal new bone formation, lysis of tuft, lytic lesions, evidence of trauma, osteomyelitis, and osteochondritis dissecans...
June 2, 2018: International Journal of Legal Medicine
Karoliina Mikola, Alessandro Piras, Laura Hakala
CASE HISTORY:  Five juvenile Labrador Retrievers between the ages of 6 and 8 months were presented to our referral centres with a history of intermittent forelimb lameness. CLINICAL EXAMINATION:  The clinical examination revealed the presence of bilateral orthopaedic problems in four out of five cases. DIAGNOSTIC IMAGING FINDINGS:  Radiographic and computed tomography examinations showed the presence of a radiolucent defect corresponding to the area of insertion of the infraspinatus or supraspinatus tendons on the proximal humerus...
June 2, 2018: Veterinary and Comparative Orthopaedics and Traumatology: V.C.O.T
Joseph D Lamplot, Perry L Schoenecker, Cecilia Pascual-Garrido, Jeffery J Nepple, John C Clohisy
BACKGROUND: Osteochondritis dissecans (OCD) is estimated to occur in 2% to 7% of patients with Legg-Calvé-Perthes disease (LCPD). Unstable osteochondral fragments secondary to LCPD may produce mechanical symptoms requiring surgical intervention. Reattachment of the fragment with open reduction and internal fixation (ORIF) may provide good clinical outcomes. The purpose of this study is to report short-term clinical and radiographic results of ORIF for the treatment of symptomatic osteochondral lesions resulting from LCPD...
May 29, 2018: Journal of Pediatric Orthopedics
Yamini Krishnan, Alan J Grodzinsky
Hyaline cartilages, fibrocartilages and elastic cartilages play multiple roles in the human body including bearing loads in articular joints and intervertebral discs, providing joint lubrication, forming the external ears and nose, supporting the trachea, and forming the long bones during development and growth. The structure and organization of cartilage's extracellular matrix (ECM) are the primary determinants of normal function. Most diseases involving cartilage lead to dramatic changes in the ECM which can govern disease progression (e...
May 24, 2018: Matrix Biology: Journal of the International Society for Matrix Biology
Archana Ananthaharan, Per-Henrik Randsborg
BACKGROUND: This study describes the epidemiology and patient reported outcomes following juvenile osteochondritis dissecans (JOCD) of the knee. METHODS: Medical records and radiographs of patients aged 10-18years diagnosed with JOCD between 2010 and 2016 were retrospectively reviewed. The lesions were classified according to the International Cartilage Repair Society's classification. The results were evaluated with the Knee injury and Osteoarthritis Outcome Score (KOOS), the Lysholm score and a Visual Analogue Scale (VAS) for pain...
May 21, 2018: Knee
Matthias Aurich, Gunther O Hofmann, Florian Gras, Bernd Rolauffs
BACKGROUND: Autologous chondrocyte implantation (ACI) is a therapy for articular cartilage and osteochondral lesions that relies on notch- or trochlea-derived primary chondrocytes. An alternative cell source for ACI could be osteochondritis dissecans (OCD) fragment-derived chondrocytes. Assessing the potential of these cells, we investigated their characteristics ex vivo and after monolayer expansion, as monolayer expansion is an integral step of ACI. However, as monolayer expansion can induce de-differentiation, we asked whether monolayer-induced de-differentiation can be reverted through successive alginate bead culture...
May 24, 2018: BMC Musculoskeletal Disorders
Rens Bexkens, Michel P J van den Bekerom, Denise Eygendaal, Luke S Oh, Job N Doornberg
PURPOSE: To find the best topographic subchondral bone match between the capitellum and 2 proposed alternative donor sites of the ipsilateral elbow for capitellar osteochondral autologous transplantation: the non-articulating part of the radial head and the lateral olecranon tip. METHODS: In our retrospective database, 20 patients with an unremarkable computed tomography scan of the elbow despite clinical suspicion were identified for analysis. Included were patients aged 11 to 20 years with intact osseous structures and a computed tomography slice thickness of 1...
May 19, 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
Arnd Hoburg, Julia Marcella Leitsch, Gerd Diederichs, Rex Lehnigk, Carsten Perka, Roland Becker, Sven Scheffler
INTRODUCTION: Osteochondral defects of the knee may cause functional impairment of young and sportively active patients. Different surgical treatment options have been proposed using either one or two step procedures. The aim of the current study was to evaluate mid-term outcomes of combined bone grafting with autologous matrix-associated chondrogenesis (AMIC) for the treatment of large osteochondral defects. MATERIALS AND METHODS: 15 Patients with osteochondrosis dissecans of the medial femoral condyle grade III or IV according to ICRS classification were treated with a single step surgical procedure combining bone grafting and the AMIC procedure...
May 15, 2018: Archives of Orthopaedic and Trauma Surgery
Jie C Nguyen, Fang Liu, Donna G Blankenbaker, Kaitlin M Woo, Richard Kijowski
Purpose To determine whether a T2 mapping sequence could depict early changes in the composition and microstructure of cartilage overlying stable lesions of the medial femoral condyle in patients with juvenile osteochondritis dissecans (JOCD). Materials and Methods This retrospective study analyzed a sagittal T2 mapping sequence performed between September 1, 2015, and March 31, 2017, on 16 patients (10 boys and six girls; median age, 11.5 years) with 18 stable medial femoral condyle JOCD lesions and 18 age-, sex-, and skeletal maturation-matched control participants (11 boys and seven girls; median age, 11...
May 15, 2018: Radiology
Tadanao Funakoshi, Daisuke Momma, Yuki Matsui, Tamotsu Kamishima, Yuichiro Matsui, Daisuke Kawamura, Yusuke Nagano, Norimasa Iwasaki
BACKGROUND: Autologous osteochondral mosaicplasty (ie, mosaicplasty) results in satisfactory clinical outcomes and reliable return to play for patients with large or unstable lesions due to osteochondritis dissecans (OCD) of the humeral capitellum. However, the association between the healing of the reconstructed cartilage and clinical outcomes remains unclear. PURPOSE: To evaluate the efficacy of mosaicplasty in teenage athletes through use of clinical scores and imaging...
May 1, 2018: American Journal of Sports Medicine
Mark Wu, Katherine Eisenberg, Kathryn Williams, Donald S Bae
Background: Osteochondritis dissecans (OCD) of the elbow has almost exclusively been described in the humeral capitellum, with only a small number of reports describing secondary osteochondral changes in the radial head. Hypothesis: The authors hypothesized that concomitant radial head lesions (RHLs) would be seen with capitellar OCD and that patients with RHLs would present with more advanced capitellar OCD lesions and would respond better to procedures restoring articular congruity...
April 2018: Orthopaedic Journal of Sports Medicine
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