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Osteochondritis dissecan

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https://www.readbyqxmd.com/read/29766258/treatment-of-osteochondral-defects-with-a-combination-of-bone-grafting-and-amic-technique
#1
Arnd Hoburg, Julia Marcella Leitsch, Gerd Diederichs, Rex Lehnigk, Carsten Perka, Roland Becker, Sven Scheffler
INTRODUCTION: Osteochondral defects of the knee may cause functional impairment of young and sportively active patients. Different surgical treatment options have been proposed using either one or two step procedures. The aim of the current study was to evaluate mid-term outcomes of combined bone grafting with autologous matrix-associated chondrogenesis (AMIC) for the treatment of large osteochondral defects. MATERIALS AND METHODS: 15 Patients with osteochondrosis dissecans of the medial femoral condyle grade III or IV according to ICRS classification were treated with a single step surgical procedure combining bone grafting and the AMIC procedure...
May 15, 2018: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/29762089/juvenile-osteochondritis-dissecans-cartilage-t2-mapping-of-stable-medial-femoral-condyle-lesions
#2
Jie C Nguyen, Fang Liu, Donna G Blankenbaker, Kaitlin M Woo, Richard Kijowski
Purpose To determine whether a T2 mapping sequence could depict early changes in the composition and microstructure of cartilage overlying stable lesions of the medial femoral condyle in patients with juvenile osteochondritis dissecans (JOCD). Materials and Methods This retrospective study analyzed a sagittal T2 mapping sequence performed between September 1, 2015, and March 31, 2017, on 16 patients (10 boys and six girls; median age, 11.5 years) with 18 stable medial femoral condyle JOCD lesions and 18 age-, sex-, and skeletal maturation-matched control participants (11 boys and seven girls; median age, 11...
May 15, 2018: Radiology
https://www.readbyqxmd.com/read/29738680/autologous-osteochondral-mosaicplasty-for-centrally-and-laterally-located-advanced-capitellar-osteochondritis-dissecans-in-teenage-athletes-clinical-outcomes-radiography-and-magnetic-resonance-imaging-findings
#3
Tadanao Funakoshi, Daisuke Momma, Yuki Matsui, Tamotsu Kamishima, Yuichiro Matsui, Daisuke Kawamura, Yusuke Nagano, Norimasa Iwasaki
BACKGROUND: Autologous osteochondral mosaicplasty (ie, mosaicplasty) results in satisfactory clinical outcomes and reliable return to play for patients with large or unstable lesions due to osteochondritis dissecans (OCD) of the humeral capitellum. However, the association between the healing of the reconstructed cartilage and clinical outcomes remains unclear. PURPOSE: To evaluate the efficacy of mosaicplasty in teenage athletes through use of clinical scores and imaging...
May 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29707596/radial-head-changes-in-osteochondritis-dissecans-of-the-humeral-capitellum
#4
Mark Wu, Katherine Eisenberg, Kathryn Williams, Donald S Bae
Background: Osteochondritis dissecans (OCD) of the elbow has almost exclusively been described in the humeral capitellum, with only a small number of reports describing secondary osteochondral changes in the radial head. Hypothesis: The authors hypothesized that concomitant radial head lesions (RHLs) would be seen with capitellar OCD and that patients with RHLs would present with more advanced capitellar OCD lesions and would respond better to procedures restoring articular congruity...
April 2018: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/29678428/location-of-osteochondritis-dissecans-lesions-of-the-capitellum
#5
Christine C Johnson, Susanne Roberts, Douglas Mintz, Peter D Fabricant, Robert N Hotchkiss, Aaron Daluiski
PURPOSE: The location of capitellar osteochondritis dissecans (OCD) lesions in the sagittal plane guides the surgical approach, and lesion location in the coronal plane influences surgical management. Although most lesions have been reported to occur between 4 o'clock and 4:30 (120° to 135° anterior to the humerus), some lesions are located elsewhere in the capitellum. The primary aim was to define the region of the capitellum affected by OCD lesions using a novel clock-face localization system...
April 17, 2018: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29664877/juvenile-osteochondritis-dissecans-of-the-trochlea-a-cohort-study-of-34-trochlear-lesions-associated-with-sporting-activities-that-load-the-patellofemoral-joint
#6
Meghan J Price, Maria Tuca, Joseph Nguyen, Jason Silberman, Eva Luderowski, Tyler J Uppstrom, Daniel W Green
BACKGROUND: Juvenile osteochondritis dissecans (JOCD) lesions are rarely located in the trochlea and few studies have focused on the causes and outcomes of JOCD lesions in this part of the knee. The purpose of this study is to (1) evaluate the clinical characteristics and outcomes of patients who undergo surgery for JOCD in this unusual location as well as (2) assess the association between trochlear JOCD and participation in sporting activities that load the patellofemoral joint. METHODS: We conducted a retrospective cohort study of 34 trochlear JOCD lesions in 30 patients...
April 16, 2018: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/29622244/editorial-commentary-to-treat-or-not-to-treat-are-we-any-closer-to-knowing-what-to-do-with-cartilage-lesions-of-the-tibia
#7
EDITORIAL
William Bugbee
The increasing interest and use of cartilage repair procedures in the knee has led to a better understanding of when and how chondral lesions should be treated. Nonetheless, there are still key areas where we lack understanding and need better data to guide clinical decision making. One of these areas is how to manage lesions of the tibia, particularly when they occur in conjunction with the more commonplace lesions of the femoral condyle. In this setting, a tibial chondral lesion may reflect a bigger clinical problem-a "bipolar defect" or more advanced joint disease-"established osteoarthritis...
April 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29613834/incidence-of-osteochondritis-dissecans-in-adults
#8
Jennifer M Weiss, Kevin G Shea, John C Jacobs, Peter C Cannamela, Ian Becker, Mark Portman, Jeffrey I Kessler
BACKGROUND: Osteochondritis dissecans (OCD) has frequently been described in children and adolescents, but cases of OCD in adults are certainly encountered. Little has been published on the epidemiology of OCD in adult patients. PURPOSE: To assess the frequency of OCD lesions in adults and assess the risk by age, sex, and ethnicity. STUDY DESIGN: Descriptive epidemiology study. METHODS: The authors assessed all patients aged 20 to 45 years from the entire database of patients enrolled as members of Kaiser Permanente Southern California from January 2011 until December 2013...
April 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29603790/arthroscopic-removal-of-osteochondral-fragments-in-the-dorsal-pouch-of-the-proximal-intertarsal-joint-in-29-horses
#9
Pablo Espinosa Mur, Nathalie Coté, Marc R Desjardins
OBJECTIVE: To describe the radiographic and surgical findings of horses with osteochondral fragments (OCF) in the proximal intertarsal joint (PIJ) and to detail the technique for arthroscopic fragment retrieval and report outcomes. STUDY DESIGN: Retrospective case series. ANIMALS: Twenty-nine horses (32 tarsi) with OCF in the PIJ. METHODS: Medical records of horses with radiographic evidence of OCF in the PIJ were reviewed...
March 30, 2018: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/29568785/articular-cartilage-repair-of-the-knee-in-children-and-adolescents
#10
REVIEW
Gian M Salzmann, Philipp Niemeyer, Alfred Hochrein, Martin J Stoddart, Peter Angele
Articular cartilage predominantly serves a biomechanical function, which begins in utero and further develops during growth and locomotion. With regard to its 2-tissue structure (chondrocytes and matrix), the regenerative potential of hyaline cartilage defects is limited. Children and adolescents are increasingly suffering from articular cartilage and osteochondral deficiencies. Traumatic incidents often result in damage to the joint surfaces, while repetitive microtrauma may cause osteochondritis dissecans...
March 2018: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/29557795/management-of-osteochondritis-dissecans-of-the-femoral-condyle-a-critical-analysis-review
#11
Charles Chan, Connor Richmond, Kevin G Shea, Steven L Frick
No abstract text is available yet for this article.
March 2018: JBJS Reviews
https://www.readbyqxmd.com/read/29534283/treatment-of-osteochondrosis-dissecans-of-the-canine-stifle-using-synthetic-osteochondral-resurfacing
#12
Pádraig Egan, Susan Murphy, Jelena Jovanovik, Russell Tucker, Noel Fitzpatrick
OBJECTIVE:  This article aimed to describe the use and evolution of a synthetic osteochondral resurfacing (SOR) implant in the treatment of osteochondrosis dissecans (OCD) of the femoral condyle and to report the clinical, radiographic, computed tomography and magnetic resonance imaging outcomes of this technique. METHODS:  Medical records of dogs that were treated with first-generation (G1) and second-generation (G2) SOR at a single institute were reviewed...
February 2018: Veterinary and Comparative Orthopaedics and Traumatology: V.C.O.T
https://www.readbyqxmd.com/read/29477668/variation-in-stress-distribution-patterns-across-the-radial-head-fovea-in-osteochondritis-dissecans-predictive-factors-in-radiographic-findings
#13
Yuki Matsui, Tadanao Funakoshi, Daisuke Momma, Azusa Miyamoto, Kaori Endo, Kozo Furushima, Kazuhiro Fujisaki, Norimasa Iwasaki
BACKGROUND: Predictive factors for the development of osteoarthritis in adolescent osteochondritis dissecans (OCD) of the humeral capitellum remain unclear. The objectives of this study were to assess subchondral bone density in the radial head fovea of patients with OCD and to evaluate stress distribution in the radiocapitellar joint. The relationship between radiologic classification and stress distribution, according to multivariate ordinal regression analysis, was also investigated...
May 2018: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/29468901/osteochondritis-dissecans-of-the-knee-conservative-treatment-strategies-a-systematic-review
#14
Luca Andriolo, Christian Candrian, Tiziana Papio, Alessia Cavicchioli, Francesco Perdisa, Giuseppe Filardo
Objective Osteochondritis dissecans (OCD) lesions are a relevant problem that affects the long-term prognosis of young patients. The purpose of this study was to analyze the evidence on potential and indications of nonsurgical treatment strategies for knee OCD. Design The search was conducted on 3 medical electronic databases according to PRISMA guidelines, including reports of any level of evidence dealing with the conservative management of knee OCD. Of 1688 identified records, 55 full-text articles were screened: 27 studies met the inclusion criteria, for a total of 908 knees, and were used for the analysis...
February 1, 2018: Cartilage
https://www.readbyqxmd.com/read/29464738/heterozygous-aggrecan-variants-are-associated-with-short-stature-and-brachydactyly-description-of-16-probands-and-a-review-of-the-literature
#15
Lucía Sentchordi-Montané, Miriam Aza-Carmona, Sara Benito-Sanz, Ana C Barreda-Bonis, Consuelo Sánchez-Garre, Pablo Prieto-Matos, Pablo Ruiz-Ocaña, Alfonso Lechuga-Sancho, Atilano Carcavilla-Urquí, Inés Mulero-Collantes, Gabriel A Martos-Moreno, Angela Del Pozo, Elena Vallespín, Amaka Offiah, Manuel Parrón-Pajares, Isabel Dinis, Sergio B Sousa, Purificación Ros-Pérez, Isabel González-Casado, Karen E Heath
OBJECTIVE: Mutations in the aggrecan gene (ACAN) have been identified in two autosomal dominant skeletal dysplasias, spondyloepiphyseal dysplasia, Kimberley type (SEDK), and osteochondritis dissecans, as well as in a severe recessive dysplasia, spondyloepimetaphyseal dysplasia, aggrecan type. Next-generation sequencing (NGS) has aided the identification of heterozygous ACAN mutations in individuals with short stature, minor skeletal defects and mild facial dysmorphisms, some of whom have advanced bone age (BA), poor pubertal spurt and early growth cessation as well as precocious osteoarthritis...
February 21, 2018: Clinical Endocrinology
https://www.readbyqxmd.com/read/29460985/characterization-of-cellular-and-matrix-alterations-in-the-early-pathogenesis-of-osteochondritis-dissecans-in-pigs-using-second-harmonic-generation-and-two-photon-excitation-fluorescence-microscopy
#16
Andreas Finnøy, Kristin Olstad, Magnus B Lilledahl
Osteochondritis dissecans is a joint disease that is observed in several species. The disease can develop as a cause of ischemic chondronecrosis in the epiphyseal growth cartilage. Some lesions of chondronecrosis undergo spontaneous resolution, but it is not possible to predict whether a lesion will resolve or progress and require intervention. Proliferation of cells into clusters occurs at the lesion margin, but it is unclear if the clusters have a repair function. The aims of the current study were to examine clusters and potential matrix changes in response to ischemic chondronecrosis in the distal femur of 10 pigs aged 70-180 days using advanced microscopy based on two-photon excitation fluorescence and second harmonic generation...
February 20, 2018: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29442213/elbow-injuries-in-the-adolescent-thrower
#17
REVIEW
Timothy B Griffith, James Kercher, S Clifton Willimon, Crystal Perkins, Xavier A Duralde
PURPOSE OF REVIEW: With an increasing rate of adolescent elbow injuries, especially in throwing athletes, the purpose of this review is to investigate the current literature regarding the diagnosis, treatment, and non-operative and operative outcomes of medial epicondyle fractures, ulnar collateral ligament repair, osteochondritis dissecans of the elbow, and olecranon stress fractures. RECENT FINDINGS: Acceptable outcomes with both non-operative and operative treatments of medial epicondyle fractures have been reported, with surgical indications continuing to evolve...
March 2018: Current Reviews in Musculoskeletal Medicine
https://www.readbyqxmd.com/read/29406414/pediatric-musculoskeletal-interventional-mri
#18
Roberto Blanco Sequeiros, Juha-Jaakko Sinikumpu, Risto Ojala, Jyri Järvinen, Jan Fritz
Minimally invasive procedures play a crucial role in the diagnosis and treatment of many pediatric musculoskeletal conditions. Although computed tomography and fluoroscopy are commonly used for image guidance, the associated exposure to ionizing radiation is especially concerning in pediatric patients. Ultrasonography may be used successfully in a subset of interventions, but it is often not useful for complex, deep, and osseous targets. Interventional magnetic resonance imaging (iMRI) facilitates targeting and treatment of musculoskeletal lesions at many locations with high accuracy due to its excellent tissue contrast...
February 2018: Topics in Magnetic Resonance Imaging: TMRI
https://www.readbyqxmd.com/read/29396963/cartilage-restoration-microfracture-and-osteochondral-autograft-transplantation
#19
Michael L Redondo, Adam J Beer, Adam B Yanke
The treatment of patellofemoral cartilage defects presents several distinct challenges when compared with cartilage restoration techniques used for other compartments of the knee due to the unique anatomy and distribution of forces. The etiologies of patellofemoral articular cartilage lesions include acute traumatic instability injuries, such as dislocation and subluxation, osteochondritis dissecans, and chronic degenerative changes. Regardless of the etiology, untreated patellofemoral cartilage lesions can contribute to activity-limiting anterior knee pain...
March 2018: Journal of Knee Surgery
https://www.readbyqxmd.com/read/29381884/osteochondral-injuries-of-the-knee-in-pediatric-patients
#20
Kathryn L Bauer
Osteochondral injuries in pediatric patients may occur as a result of a traumatic injury or secondary to an osteochondritis dissecans (OCD) lesion. Lateral patella dislocation is a common traumatic cause of osteochondral injury that typically occurs at the medial facet of the patella or at the lateral aspect of the distal femur. Multiple theories have been proposed for the cause of an OCD lesion in the knee, including trauma or repetitive microtrauma, local vascular insufficiency, and family history. The most "classic" location for OCD lesions of the knee is the lateral aspect of the medial femoral condyle of the distal femur...
May 2018: Journal of Knee Surgery
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