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https://www.readbyqxmd.com/read/28821863/the-heat-shock-response-and-humoral-immune-response-are-mutually-antagonistic-in-honey-bees
#1
Mia McKinstry, Charlie Chung, Henry Truong, Brittany A Johnston, Jonathan W Snow
The honey bee is of paramount importance to humans in both agricultural and ecological settings. Honey bee colonies have suffered from increased attrition in recent years, stemming from complex interacting stresses. Defining common cellular stress responses elicited by these stressors represents a key step in understanding potential synergies. The proteostasis network is a highly conserved network of cellular stress responses involved in maintaining the homeostasis of protein production and function. Here, we have characterized the Heat Shock Response (HSR), one branch of this network, and found that its core components are conserved...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28821648/bilingual-language-switching-in-the-lab-vs-in-the-wild-the-spatio-temporal-dynamics-of-adaptive-language-control
#2
Esti Blanco-Elorrieta, Liina Pylkkänen
For a bilingual human, every utterance requires a choice about which language to use. This choice is commonly regarded as part of general executive control, engaging prefrontal and anterior cingulate cortices similarly to many types of effortful task-switching. However, while language control within artificial switching paradigms has been heavily studied, the neurobiology of natural switching within socially cued situations has not been characterized. Additionally, although theoretical models address how language control mechanisms adapt to the distinct demands of different interactional contexts, these predictions have not been empirically tested...
August 16, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28821408/is-late-life-dependency-increasing-or-not-a-comparison-of-the-cognitive-function-and-ageing-studies-cfas
#3
Andrew Kingston, Pia Wohland, Raphael Wittenberg, Louise Robinson, Carol Brayne, Fiona E Matthews, Carol Jagger
BACKGROUND: Little is known about how the proportions of dependency states have changed between generational cohorts of older people. We aimed to estimate years lived in different dependency states at age 65 years in 1991 and 2011, and new projections of future demand for care. METHODS: In this population-based study, we compared two Cognitive Function and Ageing Studies (CFAS I and CFAS II) of older people (aged ≥65 years) who were permanently registered with a general practice in three defined geographical areas (Cambridgeshire, Newcastle, and Nottingham; UK)...
August 14, 2017: Lancet
https://www.readbyqxmd.com/read/28820668/mental-health-and-coping-patterns-in-jewish-gay-men-in-israel-the-role-of-dual-identity-conflict-religious-identity-and-partnership-status
#4
Moshe Zeidner, Attara Zevulun
This study examined the effects of dual identity conflict, religious identity (religious/spiritual vs. sexual), and partnership status on the coping strategies and mental health of gay Jewish men in modern Israeli society. Participants were 73 religious and 71 secular gay men recruited via email, social networking sites, and online resources targeting sexual minority men. Participants were assessed via measures of identity conflict, mental health, and coping strategies. Jewish gay men who reported more severe identity conflict also reported using less problem-focused, emotion-focused, and avoidance coping strategies and reported poorer mental health than their less identity-conflicted counterparts...
August 18, 2017: Journal of Homosexuality
https://www.readbyqxmd.com/read/28820435/healthy-ageing-in-people-with-intellectual-disabilities-from-managers-perspective-a-qualitative-study
#5
Maria Johansson, Petra Björne, Ingrid Runesson, Gerd Ahlström
An increasing number of people with intellectual disability (ID) are reaching older ages today although they experience more health problems than the older population without ID. Leaders in intellectual disability services can greatly influence the conditions for a healthy ageing, and the aim of the present study was to explore healthy ageing in this group from the perspective of the leaders. Interviews with 20 leaders were subjected to qualitative content analysis. The findings gave rise to the overall theme ageing in dependence, which emerged from the following six categories: Supporting self-determination; Inaccessible activities after retirement; Signs of decline; Increased and specific needs for support and care; A non-question of gender; Aspects concerning the end of life and death...
August 18, 2017: Healthcare (Basel, Switzerland)
https://www.readbyqxmd.com/read/28819355/box-office-forecasting-considering-competitive-environment-and-word-of-mouth-in-social-networks-a-case-study-of-korean-film-market
#6
Taegu Kim, Jungsik Hong, Pilsung Kang
Accurate box office forecasting models are developed by considering competition and word-of-mouth (WOM) effects in addition to screening-related information. Nationality, genre, ratings, and distributors of motion pictures running concurrently with the target motion picture are used to describe the competition, whereas the numbers of informative, positive, and negative mentions posted on social network services (SNS) are used to gauge the atmosphere spread by WOM. Among these candidate variables, only significant variables are selected by genetic algorithm (GA), based on which machine learning algorithms are trained to build forecasting models...
2017: Computational Intelligence and Neuroscience
https://www.readbyqxmd.com/read/28819293/effects-of-temporal-correlations-in-social-multiplex-networks
#7
Michele Starnini, Andrea Baronchelli, Romualdo Pastor-Satorras
Multi-layered networks represent a major advance in the description of natural complex systems, and their study has shed light on new physical phenomena. Despite its importance, however, the role of the temporal dimension in their structure and function has not been investigated in much detail so far. Here we study the temporal correlations between layers exhibited by real social multiplex networks. At a basic level, the presence of such correlations implies a certain degree of predictability in the contact pattern, as we quantify by an extension of the entropy and mutual information analyses proposed for the single-layer case...
August 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28819117/neuronal-encoding-of-self-and-others-head-rotation-in-the-macaque-dorsal-prefrontal-cortex
#8
M Lanzilotto, M Gerbella, V Perciavalle, C Lucchetti
Following gaze is a crucial skill, in primates, for understanding where and at what others are looking, and often requires head rotation. The neural basis underlying head rotation are deemed to overlap with the parieto-frontal attention/gaze-shift network. Here, we show that a set of neurons in monkey's Brodmann area 9/46dr (BA 9/46dr), which is involved in orienting processes and joint attention, becomes active during self head rotation and that the activity of these neurons cannot be accounted for by saccade-related activity (head-rotation neurons)...
August 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28818915/collaborative-environmental-governance-achieving-collective-action-in-social-ecological-systems
#9
REVIEW
Örjan Bodin
Managing ecosystems is challenging because of the high number of stakeholders, the permeability of man-made political and jurisdictional demarcations in relation to the temporal and spatial extent of biophysical processes, and a limited understanding of complex ecosystem and societal dynamics. Given these conditions, collaborative governance is commonly put forward as the preferred means of addressing environmental problems. Under this paradigm, a deeper understanding of if, when, and how collaboration is effective, and when other means of addressing environmental problems are better suited, is needed...
August 18, 2017: Science
https://www.readbyqxmd.com/read/28818845/a-scoping-review-for-strategies-to-increase-living-kidney-donation
#10
Lianne Barnieh, David Collister, Braden Manns, Ngan N Lam, Soroush Shojai, Diane Lorenzetti, John S Gill, Scott Klarenbach
BACKGROUND AND OBJECTIVES: The literature on strategies to increase the number of potential living kidney donors is extensive and has yet to be characterized. Scoping reviews are a novel methodology for systematically assessing a wide breadth of a given body of literature and may be done before conducting a more targeted systematic review. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We performed a scoping review and summarized the evidence for existing strategies to increase living kidney donation...
August 17, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28818821/patient-participation-at-health-care-conferences-engaged-patients-increase-information-flow-expand-propagation-and-deepen-engagement-in-the-conversation-of-tweets-compared-to-physicians-or-researchers
#11
Audun Utengen, Dara Rouholiman, Jamison G Gamble, Francisco Jose Grajales Iii, Nisha Pradhan, Alicia C Staley, Liza Bernstein, Sean D Young, Kevin A Clauson, Larry F Chu
BACKGROUND: Health care conferences present a unique opportunity to network, spark innovation, and disseminate novel information to a large audience, but the dissemination of information typically stays within very specific networks. Social network analysis can be adopted to understand the flow of information between virtual social communities and the role of patients within the network. OBJECTIVE: The purpose of this study is to examine the impact engaged patients bring to health care conference social media information flow and how they expand dissemination and distribution of tweets compared to other health care conference stakeholders such as physicians and researchers...
August 17, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28818735/prospective-assessment-of-social-network-quality-among-depressed-mothers-treated-with-brief-psychotherapy-the-social-network-quality-snq-scales
#12
Luis E Flores, Jill M Cyranowski, Marlissa Amole, Holly A Swartz
OBJECTIVE: Social relationships play important roles in emotional health, and are common targets of psychotherapeutic interventions. To better evaluate social relationship structure and function in the context of psychotherapy trials, this study introduces and psychometrically evaluates the Social Network Quality (SNQ) scales, which supplement the Social Network Index (SNI). The original SNI evaluates social network structure (i.e., extent of participation in diverse social roles and number of social relationships)...
July 20, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28818421/erbb-signaling-antagonist-ameliorates-behavioral-deficit-induced-by-phencyclidine-pcp-in-mice-without-affecting-metabolic-syndrome-markers
#13
Hagar Tadmor, Idit Golani, Ravid Doron, Ilana Kremer, Alon Shamir
Schizophrenia is a severe syndrome that affects about 1% of the world population. Since the mid-1950s, antipsychotics have been used to treat schizophrenia with preference for treating positive symptoms; however, their tolerance level is low, there are numerous side effects, and only some patients respond to the treatment. Antipsychotic medications that are more effective, better tolerated, and with fewer adverse effects are urgently needed. Given the accumulating evidence of the role filled by the ErbB signaling network in the biology of the dopamine, GABA, and glutamate systems, and in the etiology of schizophrenia, we hypothesized that the ErbB network is a candidate for development of a novel agent through which various symptoms of schizophrenia and other psychiatric disorders might be treated...
August 14, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28818075/perspectives-of-basic-wheelchair-users-on-improving-their-access-to-wheelchair-services-in-kenya-and-philippines-a-qualitative-study
#14
Emma Williams, Elizabeth Hurwitz, Immaculate Obaga, Brenda Onguti, Adovich Rivera, Tyrone Reden L Sy, R Lee Kirby, Jamie Noon, Deepti Tanuku, Anthony Gichangi, Eva Bazant
BACKGROUND: The United Nations has called for countries to improve access to mobility devices when needed. The World Health Organization has published guidelines on the provision of manual wheelchairs in less-resourced settings. Yet little is known about the extent to which appropriate wheelchairs are available and provided according to international guidelines. This study's purpose was to describe wheelchair users' experiences receiving services and acquiring wheelchair skills in urban and peri-urban areas of Kenya and the Philippines...
August 17, 2017: BMC International Health and Human Rights
https://www.readbyqxmd.com/read/28817951/cessation-related-information-motivation-and-behavioral-skills-in-smokers-living-with-hiv
#15
Daniel Shirley, Laura Thibodeau, Sheryl L Catz, Katryna McCoy, Douglas E Jorenby, Nasia Safdar, James M Sosman
There is a need for new, targeted smoking cessation interventions for smokers living with HIV. The Information-Motivation-Behavioral Skills (IMB) model has been applied effectively to HIV-related health behaviors and was used in this qualitative study to elicit factors that could lead to the development of innovative and successful cessation interventions for this population. Twenty individuals who smoked from two clinics providing care to people living with HIV participated in open-ended interviews, responding to questions covering the domains of the IMB model, as applied to smokers living with HIV...
August 17, 2017: AIDS Care
https://www.readbyqxmd.com/read/28817710/excessive-use-of-wechat-social-interaction-and-locus-of-control-among-college-students-in-china
#16
Juan Hou, Yamikani Ndasauka, Yingying Jiang, Zi Ye, Ying Wang, Lizhuang Yang, Xiaoming Li, Yongjun Zhang, Liangjun Pang, Yan Kong, Fei Xu, Xiaochu Zhang
In China, the number of college students using mobile phone based messaging and social networking applications like WeChat is increasing rapidly. However, there has been minimal research into the addictive nature of these applications and the psychological characteristics associate with their excessive use. There is also no published scale available for assessing excessive use of WeChat and similar applications. In the current study, we collected data from 1,245 college students in China (715 females) and developed the WeChat Excessive Use Scale (WEUS)...
2017: PloS One
https://www.readbyqxmd.com/read/28817627/analysing-researchers-outreach-efforts-and-the-association-with-publication-metrics-a-case-study-of-kudos
#17
Mojisola Erdt, Htet Htet Aung, Ashley Sara Aw, Charlie Rapple, Yin-Leng Theng
With the growth of scholarly collaboration networks and social communication platforms, members of the scholarly community are experimenting with their approach to disseminating research outputs, in an effort to increase their audience and outreach. However, from a researcher's point of view, it is difficult to determine whether efforts to make work more visible are worthwhile (in terms of the association with publication metrics) and within that, difficult to assess which platform or network is most effective for sharing work and connecting to a wider audience...
2017: PloS One
https://www.readbyqxmd.com/read/28817587/network-characteristics-and-patent-value-evidence-from-the-light-emitting-diode-industry
#18
Way-Ren Huang, Chia-Jen Hsieh, Ke-Chiun Chang, Yen-Jo Kiang, Chien-Chung Yuan, Woei-Chyn Chu
This study proposes a different angle to social network analysis that evaluates patent value and explores its influencing factors using the network centrality and network position. This study utilizes a logistic regression model to explore the relationships in the LED industry between patent value and network centrality as measured from out-degree centrality, in-degree centrality, in-closeness centrality, and network position, which is measured from effect size. The empirical result shows that out-degree centrality and in-degree centrality have significant positive effects on patent value and that effect size has a significant negative effect on patent value...
2017: PloS One
https://www.readbyqxmd.com/read/28817430/beyond-citation-rates-a-real-time-impact-analysis-of-health-professions-education-research-using-altmetrics
#19
Lauren A Maggio, Holly S Meyer, Anthony R Artino
PURPOSE: To complement traditional citation-based metrics, which take years to accrue and indicate only academic attention, academia has begun considering altmetrics or alternative metrics, which provide timely feedback on an article's impact by tracking its dissemination via nontraditional outlets, such as blogs and social media, across audiences. This article describes altmetrics and examines altmetrics attention, outlets used, and top article characteristics for health professions education (HPE) research...
August 16, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28817429/the-rising-challenge-of-training-physician-scientists-recommendations-from-a-canadian-national-consensus-conference
#20
Michael J Strong, Nick Busing, Danika L Goosney, Ken A Harris, Tanya Horsley, Alexandra Kuzyk, Lorelei Lingard, Wendy V Norman, Norman D Rosenblum, Tina Saryeddine, Xin Wang
Physician-scientists are individuals who actively participate in patient care, have undergone additional research training, and devote the majority of their time to research. Physician-scientists are traditionally the primary catalysts in bridging the translational gap-that is, the failure to link fundamental new knowledge in the pathobiology of disease with advances in health care and health policy in a timely manner. However, there has been a shift away from training physician-scientists, and financial support for the physician-scientist is diminishing globally, causing the translational gap to grow...
August 16, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
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