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https://www.readbyqxmd.com/read/28790923/gut-microbiome-response-to-sucralose-and-its-potential-role-in-inducing-liver-inflammation-in-mice
#1
Xiaoming Bian, Liang Chi, Bei Gao, Pengcheng Tu, Hongyu Ru, Kun Lu
Sucralose is the most widely used artificial sweetener, and its health effects have been highly debated over the years. In particular, previous studies have shown that sucralose consumption can alter the gut microbiota. The gut microbiome plays a key role in processes related to host health, such as food digestion and fermentation, immune cell development, and enteric nervous system regulation. Inflammation is one of the most common effects associated with gut microbiome dysbiosis, which has been linked to a series of human diseases, such as diabetes and obesity...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28789721/sociodemographic-lifestyle-and-behavioural-factors-associated-with-consumption-of-sweetened-beverages-among-adults-in-cambridgeshire-uk-the-fenland-study
#2
Peter Barrett, Fumiaki Imamura, Søren Brage, Simon J Griffin, Nicholas J Wareham, Nita G Forouhi
OBJECTIVE: We aimed to identify sociodemographic, lifestyle and behavioural determinants of consumption of sugar-sweetened beverages (SSB) and artificially sweetened beverages (ASB) among adults in Cambridgeshire, UK. DESIGN: Cross-sectional data were obtained from a cohort of 9991 adults born between 1950 and 1975. An FFQ was used to assess consumption of beverages and other dietary factors. Multivariable logistic regression was used to examine potential determinants of consuming SSB and ASB (≥1 serving/d)...
August 9, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28782989/longitudinal-modelling-of-the-exposure-of-young-uk-patients-with-pku-to-acesulfame-k-and-sucralose
#3
J Aaron O'Sullivan, Sandrine Pigat, Cian O'Mahony, Michael J Gibney, Aideen I McKevitt
Artificial sweeteners are used in protein substitutes intended for the dietary management of inborn errors of metabolism (Phenylketonuria, PKU) to improve the variety of medical foods available to patients and ensure dietary adherence to the prescribed course of dietary management. These patients can be exposed to artificial sweeteners from the combination of free and prescribed foods. Young children have a higher risk of exceeding acceptable daily intakes (ADI) for additives than adults due to higher food intakes per kg body weight...
August 7, 2017: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/28781184/contaminants-of-emerging-concern-in-the-open-sea-waters-of-the-western-mediterranean
#4
Miroslav Brumovský, Jitka Bečanová, Jiří Kohoutek, Mireno Borghini, Luca Nizzetto
Pollution by chemical substances is of concern for the maintenance of healthy and sustainable aquatic environments. While the occurrence and fate of numerous emerging contaminants, especially pharmaceuticals, is well documented in freshwater, their occurrence and behavior in coastal and marine waters is much less studied and understood. This study investigates the occurrence of 58 chemicals in the open surface water of the Western Mediterranean Sea for the first time. 70 samples in total were collected in 10 different sampling areas...
August 3, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28741247/contaminants-of-emerging-concern-a-review-of-new-approach-in-aop-technologies
#5
REVIEW
Maryam Salimi, Ali Esrafili, Mitra Gholami, Ahmad Jonidi Jafari, Roshanak Rezaei Kalantary, Mahdi Farzadkia, Majid Kermani, Hamid Reza Sobhi
The presence of contaminants of emerging concern (CECs) such as pharmaceuticals and personal care products (PPCPs), endocrine-disrupting compounds (EDCs), flame retardants (FRs), pesticides, and artificial sweeteners (ASWs) in the aquatic environments remains a major challenge to the environment and human health. In this review, the classification and occurrence of emerging contaminants in aquatic environments were discussed in detail. It is well documented that CECs are susceptible to poor removal during the conventional wastewater treatment plants, which introduce them back to the environment ranging from nanogram per liter (e...
August 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28736783/halogen-effects-on-the-solid-state-packing-of-phenylalanine-derivatives-and-the-resultant-gelation-properties
#6
Susana M Ramalhete, Jamie S Foster, Hayley R Green, Karol P Nartowski, Margaux Heinrich, Peter C Martin, Yaroslav Z Khimyak, Gareth O Lloyd
Phenylalanine is an important amino acid both biologically, essential to human health, and industrially, as a building block of artificial sweeteners. Our interest in this particular amino acid and its derivatives lies with its ability to form gels in a number of solvents. We present here the studies of the influence of halogen addition to the aromatic ring on the gelation properties and we analyse the crystal structures of a number of these materials to elucidate the trends in their behaviour based on the halogen addition to the aromatic group and the interactions that result...
July 24, 2017: Faraday Discussions
https://www.readbyqxmd.com/read/28690302/a-rapid-dialysis-method-for-analysis-of-artificial-sweeteners-in-foods-2nd-report
#7
Shoichi Tahara, Sumiyo Yamamoto, Yukiko Yamajima, Hiroyuki Miyakawa, Yoko Uematsu, Kimio Monma
Following the previous report, a rapid dialysis method was developed for the extraction and purification of four artificial sweeteners, namely, sodium saccharide (Sa), acesulfame potassium (AK), aspartame (APM), and dulcin (Du), which are present in various foods. The method was evaluated by the addition of 0.02 g/kg of these sweeteners to a cookie sample, in the same manner as in the previous report. Revisions from the previous method were: reduction of the total dialysis volume from 200 to 100 mL, change of tube length from 55 to 50 cm, change of dialysate from 0...
2017: Shokuhin Eiseigaku Zasshi. Journal of the Food Hygienic Society of Japan
https://www.readbyqxmd.com/read/28675883/mass-loading-of-typical-artificial-sweeteners-in-a-pig-farm-and-their-dissipation-and-uptake-by-plants-in-neighboring-farmland
#8
Ling Ma, Yarui Liu, Jiayao Xu, Hongwen Sun, Hao Chen, Yiming Yao, Peng Zhang, Fengju Shen, Aldredo C Alder
Pig farm is an important potential source for artificial sweeteners (ASs) in the environment due to their wide use as additives in pig feed. The objective of this study was to evaluate the fate of typical ASs in pig farm and neighboring farmland. For this purpose, the levels of four typical artificial ASs, i.e. saccharin (SAC), cyclamate (CYC), acesulfame (ACE) and sucralose (SUC), in pig feed and manure from a pig farm and water samples from an on-farm wastewater treatment plant (WWTP) in Tianjin, China were measured and the mass loadings and removal efficiencies were assessed...
July 1, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28659294/artificially-sweetened-beverages-sugar-sweetened-beverages-plain-water-and-incident-diabetes-mellitus-in-postmenopausal-women-the-prospective-women-s-health-initiative-observational-study
#9
Mengna Huang, Abdullah Quddus, Lynda Stinson, James M Shikany, Barbara V Howard, Randa M Kutob, Bing Lu, JoAnn E Manson, Charles B Eaton
Background: Sugar-sweetened beverages (SSBs) have been associated with an increased risk of diabetes mellitus (DM), whereas the association with artificially sweetened beverages (ASBs) is unclear.Objective: We aimed to evaluate the associations of ASB and SSB consumption with the risk of developing DM and the potential benefit of replacing SSBs with ASBs or water.Design: The national Women's Health Initiative recruited a large prospective cohort of postmenopausal women between 1993 and 1998. ASB, SSB, and water consumption was measured by lifestyle questionnaires, and DM was self-reported...
August 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28618659/projected-impact-of-climate-change-and-chemical-emissions-on-the-water-quality-of-the-european-rivers-rhine-and-meuse-a-drinking-water-perspective
#10
Rosa M A Sjerps, Thomas L Ter Laak, Gertjan J J G Zwolsman
Low river discharges of the rivers Rhine and Meuse are expected to occur more often and more prolonged in a changing climate. During these dry periods the dilution of point sources such as sewage effluents is reduced leading to a decline in chemical water quality. This study projects chemical water quality of the rivers Rhine and Meuse in the year 2050, based on projections of chemical emissions and two climate scenarios: moderate and fast climate change. It focuses on specific compounds known to be relevant to drinking water production, i...
December 1, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28618238/antiglycating-potential-of-acesulfame-potassium-an-artificial-sweetener
#11
Ahmad Ali, Tejashree Anil More, Amaritpal Kaur Hoonjan, Subramanian Sivakami
Sweeteners have replaced the natural sugars in the food and beverage industry because of many reasons, such as hyperglycemia and cost. Saccharin, sucralose, aspartame and acesulfame-K are the most commonly used sweeteners. In the present study, the abovementioned artificial sweeteners were used to assess their glycating properties by established methods such as browning, fructosamine assay, determination of carbonyl content, protein aggregation, and measurement of fluorescence. Amadori and advanced glycation end products (AGEs) are formed as a result of the interaction between carbonyl groups of reducing sugars and amino groups of proteins and other macromolecules during glycation...
June 15, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28614740/investigation-of-ozonation-kinetics-and-transformation-products-of-sucralose
#12
Ruikang Hu, Lifeng Zhang, Jiangyong Hu
Sucralose is one of widely used artificial sweeteners, which has been ubiquitously detected in various water sources, such as wastewater and randomly in reservoir water. It is also reported to be persistent to various water treatment techniques. Although there are some studies on removal of sucralose by advanced oxidation process, limited information, in terms of reaction kinetics, transformation products and degradation pathway etc., was reported in its ozonation process. In this study, the reaction kinetics, removal efficiency, influence of pH, humic acid and carbonate on sucralose degradation by ozone, have been studied systematically...
June 11, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28605847/impact-of-on-site-small-and-large-scale-wastewater-treatment-facilities-on-levels-and-fate-of-pharmaceuticals-personal-care-products-artificial-sweeteners-pesticides-and-perfluoroalkyl-substances-in-recipient-waters
#13
Pablo Gago-Ferrero, Meritxell Gros, Lutz Ahrens, Karin Wiberg
One of the main risks associated with effluents from both wastewater treatment plants (WWTPs) and on-site sewage treatment facilities (OSSFs) is the release of micropollutants (MPs) in receiving water bodies. However, the impact of MPs present in the effluents of OSSFs in the aquatic environment has not been studied so far. The current study evaluates the impact of the effluents of OSSFs and small-to-large scale WWTPs on natural waters. The discharge of 74 MPs was assessed including pharmaceuticals, personal care products, pesticides, artificial sweeteners and perfluoroalkyl substances (PFASs)...
December 1, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28598045/soft-drinks-consumption-and-the-risk-of-nonalcoholic-fatty-liver-disease
#14
Zeba Siddiqi, Ritu Karoli, Jalees Fatima, Sachin Khanduri, Shishir Varshneya, Sara Sabina Ahmad
INTRODUCTION: The increased consumption of sugar-sweetened beverages (SSBs) has been implicated in the increased incidence of obesity and metabolic syndrome Little of the research on sugar-sweetened beverage intake has examined the consumption patterns of sugared beverages by college students, despite the vulnerabilities of this population to weight gain. The current study sought to characterize sugar-sweetened beverage intake of undergraduate students who belong to high socio-economic strata and to study its correlation with presence of non-alcoholic fatty liver disease...
May 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28594855/the-artificial-sweetener-acesulfame-potassium-affects-the-gut-microbiome-and-body-weight-gain-in-cd-1-mice
#15
Xiaoming Bian, Liang Chi, Bei Gao, Pengcheng Tu, Hongyu Ru, Kun Lu
Artificial sweeteners have been widely used in the modern diet, and their observed effects on human health have been inconsistent, with both beneficial and adverse outcomes reported. Obesity and type 2 diabetes have dramatically increased in the U.S. and other countries over the last two decades. Numerous studies have indicated an important role of the gut microbiome in body weight control and glucose metabolism and regulation. Interestingly, the artificial sweetener saccharin could alter gut microbiota and induce glucose intolerance, raising questions about the contribution of artificial sweeteners to the global epidemic of obesity and diabetes...
2017: PloS One
https://www.readbyqxmd.com/read/28587159/effects-of-low-dose-non-caloric-sweetener-consumption-on-gut-microbiota-in-mice
#16
Takashi Uebanso, Ai Ohnishi, Reiko Kitayama, Ayumi Yoshimoto, Mutsumi Nakahashi, Takaaki Shimohata, Kazuaki Mawatari, Akira Takahashi
Abstract: Non-caloric artificial sweeteners (NASs) provide sweet tastes to food without adding calories or glucose. NASs can be used as alternative sweeteners for controlling blood glucose levels and weight gain. Although the consumption of NASs has increased over the past decade in Japan and other countries, whether these sweeteners affect the composition of the gut microbiome is unclear. In the present study, we examined the effects of sucralose or acesulfame-K ingestion (at most the maximum acceptable daily intake (ADI) levels, 15 mg/kg body weight) on the gut microbiome in mice...
June 1, 2017: Nutrients
https://www.readbyqxmd.com/read/28586472/maternal-consumption-of-artificially-sweetened-beverages-during-pregnancy-and-offspring-growth-through-7-years-of-age-a-prospective-cohort-study
#17
Yeyi Zhu, Sjurdur F Olsen, Pauline Mendola, Thorhallur I Halldorsson, Shristi Rawal, Stefanie N Hinkle, Edwina H Yeung, Jorge E Chavarro, Louise G Grunnet, Charlotta Granström, Anne A Bjerregaard, Frank B Hu, Cuilin Zhang
Background: Artificial sweeteners are widely replacing caloric sweeteners. Data on long-term impact of artificially sweetened beverage (ASB) consumption during pregnancy on offspring obesity risk are lacking. We prospectively investigated intake of ASBs and sugar-sweetened beverages (SSBs) during pregnancy in relation to offspring growth through age 7 years among high-risk children born to women with gestational diabetes. Methods: In a prospective study of 918 mother-singleton child dyads from the Danish National Birth Cohort, maternal dietary intake was assessed by a food frequency questionnaire during pregnancy...
June 6, 2017: International Journal of Epidemiology
https://www.readbyqxmd.com/read/28571543/aspartame-should-individuals-with-type-ii-diabetes-be-taking-it
#18
Arbind Kumar Choudhary
BACKGROUND: Individuals with type II diabetes (T2D) have to manage blood glucose levels to sustain health and longevity. Artificial sweeteners (including aspartame) are suggested sugar alternatives for these individuals. The safety of aspartame in particular, has long been the centre of debate. Although it is such a controversial product, many clinicians recommend its use to T2D patients, during a controlled diet and as part of an intervention strategy. Aspartame is 200 times sweeter than sugar and has a negligible effect on blood glucose levels, and it is suggested for use so that T2D can control carbohydrate intake and blood glucose levels...
May 31, 2017: Current Diabetes Reviews
https://www.readbyqxmd.com/read/28550797/potential-tracers-for-tracking-septic-tank-effluent-discharges-in-watercourses
#19
Samia Richards, Paul J A Withers, Eric Paterson, Colin W McRoberts, Marc Stutter
Septic tank effluent (STE) contributes to catchment nutrient and pollutant loads. To assess the role of STE discharges in impairment of surface water, it is essential to identify the sources of pollution by tracing contaminants in watercourses. We examined tracers that were present in STE to establish their potential for identifying STE contamination in two stream systems (low and high dilution levels) against the background of upstream sources. The studied tracers were microbial, organic matter fluorescence, caffeine, artificial sweeteners and effluent chemical concentrations...
September 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28548564/eating-habits-and-food-additive-intakes-are-associated-with-emotional-states-based-on-eeg-and-hrv-in-healthy-korean-children-and-adolescents
#20
Jin Young Kim, Hye Lim Kang, Dae-Keun Kim, Seung Wan Kang, Yoo Kyoung Park
PURPOSE: Recent study suggests that psychological issues and eating habits are closely related. In this study, we aimed to find the association between eating habits and intakes of artificial sweeteners with emotional states of schoolchildren using quantitatively analyzing objective biosignals. METHODS: The study was conducted at the National Standard Reference Data Center for Korean EEG as a cross-sectional study. Three hundred eighteen healthy children who have not been diagnosed with neurologic or psychiatric disorders were evaluated (168 girls and 150 boys; mean age of 11...
July 2017: Journal of the American College of Nutrition
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