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https://www.readbyqxmd.com/read/29759229/evaluation-of-polar-organic-chemical-integrative-and-hollow-fibre-samplers-for-the-determination-of-a-wide-variety-of-organic-polar-compounds-in-seawater
#1
Leire Mijangos, Haizea Ziarrusta, Ailette Prieto, Oihane Zugazua, Olatz Zuloaga, Maitane Olivares, Aresatz Usobiaga, Albrecht Paschke, Nestor Etxebarria
The calibration of two passive samplers for the determination of 20 emerging organic compounds in seawater is described in this work: i) a new version of polar organic chemical integrative sampler (POCIS) containing 100 mg of mixed-mode anion exchanger (Strata X-AW) and 100 mg of polymeric HLB (Plexa) sorbent materials and using a highly porous Nylon membrane (30-μm pore size) and ii) polyethersulfone (PES) hollow fibre. Among the studied contaminants, herbicides, hormones, life style products (stimulants and artificial sweeteners), industrial chemicals (corrosion inhibitor and fluorinated compounds), personal care products and several pharmaceuticals were included...
August 1, 2018: Talanta
https://www.readbyqxmd.com/read/29754156/-innovative-application-of-small-molecules-to-influence-pathogenicity-of-dental-plaque
#2
M M Janus, C M C Volgenant, B P Krom
Current preventive measures against infectious oral diseases are mainly focussed on plaque removal and promoting a healthy lifestyle. This in vitro study investigated a third preventive method: maintaining healthy dental plaque with the use of small molecules. As a model of dental plaque, in vitro biofilms were cultivated under conditions that induce pathogenic characteristics. The effect of erythritol and other small molecules on the pathogenic characteristics and bacterial composition of the biofilm was evaluated...
May 2018: Nederlands Tijdschrift Voor Tandheelkunde
https://www.readbyqxmd.com/read/29697292/commonly-consumed-beverages-associate-with-different-lifestyle-and-dietary-intakes
#3
Louise Brunkwall, Peter Almgren, Sophie Hellstrand, Marju Orho-Melander, Ulrika Ericson
Sugar sweetened beverages (SSB), artificially sweetened beverages (ASB), juice, coffee and tea has been associated with risk of metabolic disease. High consumption of these beverages may be associated with certain characteristics of the overall diet that would be important to take into account when analysing beverage-disease associations. Here, we investigate five beverages and their association with lifestyle and diet in 25,112 individuals from the Malmö Diet and Cancer Cohort. We observed that high consumption of SSB was associated with lower intakes of foods perceived as healthy...
April 26, 2018: International Journal of Food Sciences and Nutrition
https://www.readbyqxmd.com/read/29695387/controlled-cohort-evaluation-of-the-livelighter-mass-media-campaign-s-impact-on-adults-reported-consumption-of-sugar-sweetened-beverages
#4
Belinda C Morley, Philippa H Niven, Helen G Dixon, Maurice G Swanson, Alison B McAleese, Melanie A Wakefield
OBJECTIVE: To evaluate the LiveLighter 'Sugary Drinks' campaign impact on awareness, knowledge and sugar-sweetened beverage (SSB) consumption. DESIGN: Cohort study with population surveys undertaken in intervention and comparison states at baseline (n=900 each), with 78% retention at follow-up (intervention: n=673; comparison: n=730). Analyses tested interactions by state (intervention, comparison) and time (baseline, follow-up). SETTING AND PARTICIPANTS: Adults aged 25-49 years residing in the Australian states of Victoria and South Australia...
April 25, 2018: BMJ Open
https://www.readbyqxmd.com/read/29664905/erythritol-at-insecticidal-doses-has-harmful-effects-on-two-common-agricultural-crop-plants
#5
Sara E Scanga, Bilal Hasanspahič, Edin Zvorničanin, Jasmina Samardžić Koženjić, Andrew K Rahme, Jessica H Shinn-Thomas
Erythritol, a non-nutritive polyol, is the main component of the artificial sweetener Truvia®. Recent research has indicated that erythritol may have potential as an organic insecticide, given its harmful effects on several insects but apparent safety for mammals. However, for erythritol to have practical use as an insecticide in agricultural settings, it must have neutral to positive effects on crop plants and other non-target organisms. We examined the dose-dependent effects of erythritol (0, 5, 50, 500, 1000, and 2000 mM) on corn (Zea mays) and tomato (Solanum lycopersicum) seedling growth and seed germination...
2018: PloS One
https://www.readbyqxmd.com/read/29660810/sensory-profile-drivers-of-liking-and-influence-of-information-on-the-acceptance-of-low-calorie-synbiotic-and-probiotic-chocolate-ice-cream
#6
Juliana Peres, Erick Esmerino, Alessandra Lins da Silva, Ilana Racowski, Helena Bolini
The objective of this study was to evaluate the sensory profile and the influence of the information on the acceptance of the symbiotic chocolate ice cream made with sucrose and different sweeteners (aspartame, sucralose, neotame, Stevia with 60%, 85%, 95%, and 97% of rebaudioside A) through analysis of variance (ANOVA), Tukey's test, and partial least of square (PLS) regression. Quantitative descriptive analysis (QDA) was carried out by 18 assessors, who evaluated the samples in relation to the raised descriptors...
April 16, 2018: Journal of Food Science
https://www.readbyqxmd.com/read/29660801/evaluation-of-long-term-effects-of-artificial-sweeteners-on-rat-brain-a-biochemical-behavioral-and-histological-study
#7
Oytun Erbaş, Mümin Alper Erdoğan, Asghar Khalilnezhad, Volkan Solmaz, Fulya Tuzcu Gürkan, Gürkan Yiğittürk, Hüseyin Avni Eroglu, Dilek Taskiran
The aim of the present study was to compare the effects of artificial sweeteners (aspartame, saccharin, and sucralose) on rat brain. Twenty-four adult male Sprague-Dawley rats were included in the study. The control group (n = 6) received regular tap water, whereas other groups received aspartame (3 mg/kg/day, n = 6,) or saccharin (3 mg/kg/day, n = 6) or sucralose (1.5 mg/kg/day, n = 6) in the drinking water. Following 6 weeks, the passive avoidance learning (PAL) test was performed to evaluate the neurobehavioral effects of sweeteners...
April 16, 2018: Journal of Biochemical and Molecular Toxicology
https://www.readbyqxmd.com/read/29624909/exposure-to-liquid-sweetness-in-early-childhood-artificially-sweetened-and-sugar-sweetened-beverage-consumption-at-4-5-years-and-risk-of-overweight-and-obesity-at-7-8-years
#8
A K Macintyre, L Marryat, S Chambers
BACKGROUND: A significant gap exists in longitudinal evidence on early exposure to artificially sweetened beverages (ASBs) and weight outcomes for paediatric populations. OBJECTIVE: The objective of this study is to examine the relationship between ASB/sugar-sweetened beverage (SSB) consumption at 4-5 years and risk of overweight and obesity at 7-8 years. METHODS: Data from a nationally representative cohort (n = 2986) in Scotland were analysed using logistic regression to evaluate the association between exposure to ASBs/SSBs at 4-5 years and risk of overweight and obesity at 7-8 years...
April 6, 2018: Pediatric Obesity
https://www.readbyqxmd.com/read/29622230/hydrophilic-interaction-chromatography-in-food-matrices-analysis-an-updated-review
#9
REVIEW
Giorgio Marrubini, Patrik Appelblad, Mariarosa Maietta, Adele Papetti
This review focuses on the most recent papers (from 2011 to submission date in 2017) dealing with the analysis of different organic components in foods (i.e. nucleobases, nucleosides, nucleotides, uric acid, and creatinine, amino acids and related compounds, choline-related compounds and phospholipids, carbohydrates, artificial sweeteners and polyphenolic compounds), using hydrophilic interaction liquid chromatography (HILIC) combined with different detection techniques. For each compound class, the investigated food matrices are grouped per: foods of animal origin, vegetables, fruits and related products, baby food, and other matrices such as drinks and mushrooms/fungi...
August 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29597305/effects-of-consuming-a-low-dose-of-alcohol-with-mixers-containing-carbohydrate-or-artificial-sweetener-on-simulated-driving-performance
#10
Bryce Brickley, Ben Desbrow, Danielle McCartney, Christopher Irwin
The Australian National Drug and Alcohol Research Centre (NDARC) devised gender-based drinking recommendations to ensure blood or equivalized breath alcohol concentrations (BrAC) remain <0.050%. However, these may be inappropriate for individuals consuming alcohol without carbohydrate (CHO), which results in higher BrACs. This study investigated the effects of ingesting alcohol with and without CHO on BrACs and simulated driving performance. Thirty-two participants (16 males; age: 23 ± 6 years) completed two randomized single-blinded trials...
March 28, 2018: Nutrients
https://www.readbyqxmd.com/read/29567303/photo-fenton-treatment-of-saccharin-in-a-solar-pilot-compound-parabolic-collector-use-of-olive-mill-wastewater-as-iron-chelating-agent-preliminary-results
#11
K Davididou, E Chatzisymeon, L Perez-Estrada, I Oller, S Malato
The aim of this work was to investigate the treatment of the artificial sweetener saccharin (SAC) in a solar compound parabolic collector pilot plant by means of the photo-Fenton process at pH 2.8. Olive mill wastewater (OMW) was used as iron chelating agent to avoid acidification of water at pH 2.8. For comparative purposes, Ethylenediamine-N, N-disuccinic acid (EDDS), a well-studied iron chelator, was also employed at circumneutral pH. Degradation products formed along treatment were identified by LC-QTOF-MS analysis...
March 14, 2018: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/29554295/not-so-splendid-for-the-gut-microbiota
#12
Benoit Chassaing, Andrew T Gewirtz
A critically important new study by leading inflammatory bowel disease (IBD) researcher Fabio Cominelli and colleagues reveals that, in mice, the artificial sweetener SPLENDA deleteriously impacts the intestinal microbiota in a manner that promotes Crohn's-type disease in genetically susceptible hosts. These results suggest that consumption of this product may be a risk factor for IBD.
April 23, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29554272/the-artificial-sweetener-splenda-promotes-gut-proteobacteria-dysbiosis-and-myeloperoxidase-reactivity-in-crohn-s-disease-like-ileitis
#13
Alexander Rodriguez-Palacios, Andrew Harding, Paola Menghini, Catherine Himmelman, Mauricio Retuerto, Kourtney P Nickerson, Minh Lam, Colleen M Croniger, Mairi H McLean, Scott K Durum, Theresa T Pizarro, Mahmoud A Ghannoum, Sanja Ilic, Christine McDonald, Fabio Cominelli
Background: Epidemiological studies indicate that the use of artificial sweeteners doubles the risk for Crohn's disease (CD). Herein, we experimentally quantified the impact of 6-week supplementation with a commercial sweetener (Splenda; ingredients sucralose maltodextrin, 1:99, w/w) on both the severity of CD-like ileitis and the intestinal microbiome alterations using SAMP1/YitFc (SAMP) mice. Methods: Metagenomic shotgun DNA sequencing was first used to characterize the microbiome of ileitis-prone SAMP mice...
April 23, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29554259/gradual-reduction-of-free-sugars-in-beverages-on-sale-by-implementing-the-beverage-checklist-as-a-public-health-strategy
#14
Maria Luger, Eva Winzer, Manuel Schätzer, Sabine Dämon, Nadine Moser, Karin Blagusz, Barbara Rittmannsberger, Julia Schätzer, Monika Lechleitner, Anita Rieder, Friedrich Hoppichler
Background: Sugar-sweetened beverages (SSBs) are a major source of free sugar intake and contribute to obesity and obesity-related diseases. Therefore, we analyzed the effect of a gradual sugar reduction strategy within the so-called 'beverage checklist' on free sugar content in beverages on sale in Austria. Methods: From 2010 until 2017, data on the amount of free sugar of sweetened beverages (sweetened with sugars, fruit juice and artificial sweeteners) with 0...
March 15, 2018: European Journal of Public Health
https://www.readbyqxmd.com/read/29544207/removal-of-pharmaceuticals-perfluoroalkyl-substances-and-other-micropollutants-from-wastewater-using-lignite-xylit-sand-granular-activated-carbon-gac-and-gac-polonite-%C3%A2-in-column-tests-role-of-physicochemical-properties
#15
Ande Rostvall, Wen Zhang, Wiebke Dürig, Gunno Renman, Karin Wiberg, Lutz Ahrens, Pablo Gago-Ferrero
This study evaluated the performance of five different sorbents (granular activated carbon (GAC), GAC + Polonite® (GAC + P), Xylit, lignite and sand) for a set of 83 micropollutants (MPs) (pharmaceuticals, perfluoroalkyl substances (PFASs), personal care products, artificial sweeteners, parabens, pesticide, stimulants), together representing a wide range of physicochemical properties. Treatment with GAC and GAC + P provided the highest removal efficiencies, with average values above 97%. Removal rates were generally lower for Xylit (on average 74%) and lignite (on average 68%), although they proved to be highly efficient for a few individual MPs...
June 15, 2018: Water Research
https://www.readbyqxmd.com/read/29534506/saccharin-increases-fasting-blood-glucose-but-not-liver-insulin-resistance-in-comparison-to-a-high-fructose-fed-rat-model
#16
Avshalom Leibowitz, Ariel Bier, Mayan Gilboa, Edna Peleg, Iris Barshack, Ehud Grossman
Recent data indicate that artificial sweeteners (AS) may have deleterious effects on glucose metabolism. The purpose of this study was to compare the effects of AS and the effects of a high fructose diet (HFrD) on glucose metabolism and insulin resistance (IR) in Sprague-Dawley (SD) rats. SD rats were fed either regular chow, chow with saccharin (Sac) (0.1 mg/mL) placed in their water, or HFrD for seven weeks. Glucose, insulin, and triglycerides (Tg) levels were measured upon completion. A homeostatic model assessment (HOMA)-IR index was used to determine insulin resistance...
March 12, 2018: Nutrients
https://www.readbyqxmd.com/read/29529435/assessment-of-drugs-and-personal-care-products-biomarkers-in-the-influent-and-effluent-of-two-wastewater-treatment-plants-in-ho-chi-minh-city-vietnam
#17
Hue T Nguyen, Phong K Thai, Sarit L Kaserzon, Jake W O'Brien, Geoff Eaglesham, Jochen F Mueller
Wastewater samples were collected at the influent and effluent of two wastewater treatment plants (WWTPs) in Ho Chi Minh City, Vietnam and then pooled to daily samples over multiple days using 6 hourly grab samples. The aim was to provide a first assessment of the occurrence, consumption, removal and release of a range of organic chemicals including pharmaceuticals and personal care products (PPCPs), illicit drugs, an artificial sweetener, tobacco and its metabolites and alcohol biomarkers (referred to here as DPCPBs)...
August 1, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29508692/cross-sectional-association-between-sugar-sweetened-beverage-intake-and-cardiometabolic-biomarkers-in-us-women
#18
Zhi Yu, Sylvia H Ley, Qi Sun, Frank B Hu, Vasanti S Malik
Few studies have evaluated the relationships between intake of sugar-sweetened beverages (SSB) and intermediate biomarkers of cardiometabolic risk. Associations between artificially sweetened beverages (ASB) and fruit juice with cardiometabolic biomarkers are also unclear. We investigated habitual SSB, ASB and fruit juice intake in relation to biomarkers of hepatic function, lipid metabolism, inflammation and glucose metabolism. We analysed cross-sectional data from 8492 participants in the Nurses' Health Study who were free of diabetes and CVD...
March 2018: British Journal of Nutrition
https://www.readbyqxmd.com/read/29504081/analysis-of-a-variety-of-inorganic-and-organic-additives-in-food-products-by-ion-pairing-liquid-chromatography-coupled-to-high-resolution-mass-spectrometry
#19
Anton Kaufmann, Mirjam Widmer, Kathryn Maden, Patrick Butcher, Stephan Walker
A reversed-phase ion-pairing chromatographic method was developed for the detection and quantification of inorganic and organic anionic food additives. A single-stage high-resolution mass spectrometer (orbitrap ion trap, Orbitrap) was used to detect the accurate masses of the unfragmented analyte ions. The developed ion-pairing chromatography method was based on a dibutylamine/hexafluoro-2-propanol buffer. Dibutylamine can be charged to serve as a chromatographic ion-pairing agent. This ensures sufficient retention of inorganic and organic anions...
March 5, 2018: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/29502811/in-silico-prediction-of-sweetness-using-structure-activity-relationship-models
#20
Anukrati Goel, Kishore Gajula, Rakesh Gupta, Beena Rai
Quantitative structure activity relationship (QSAR) models appear to be an ideal tool for quick screening of promising candidates from a vast library of molecules, which can then be further designed, synthesized and tested using a combination of rigorous first principle simulations, such as molecular docking, molecular dynamics simulation and experiments. In this study, QSAR models have been built with an extensive dataset of 487 compounds to predict the sweetness potency relative to sucrose (ranging 0.2-220,000)...
July 1, 2018: Food Chemistry
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