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https://www.readbyqxmd.com/read/29140136/salt-glycerol-induced-hyperhydration-enhances-fluid-retention-more-than-salt-or-glycerol-induced-hyperhydration
#1
Eric D B Goulet, Adrien De La Flore, Félix A Savoie, Jonathan Gosselin
Hyperhydration has been demonstrated to improve work capacity and cardiovascular and thermoregulatory functions, enhance orthostatic tolerance, slow or neutralize bone demineralization and decrease post-dive bubble formation. Adding sodium or glycerol to a hyperhydration solution optimizes fluid retention. Sodium and glycerol produce their effect through different physiological mechanisms. If combined into a hyperhydration solution their impact on fluid retention could potentially be greater than their singular effect...
November 15, 2017: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/29138943/contaminants-of-emerging-concern-in-surface-waters-in-barbados-west-indies
#2
Quincy A Edwards, Sergei M Kulikov, Leah D Garner-O'Neale, Chris D Metcalfe, Tamanna Sultana
Contaminants of emerging concern (CECs), including pharmaceuticals, artificial sweeteners, steroid hormones, and current-use pesticides have been detected in surface waters around the world, but to date, there have been no reports in the peer-reviewed literature on the levels of these classes of contaminants in freshwater resources in the Caribbean region. In the present study, multi-residue solid phase extraction (SPE) and liquid chromatography with tandem mass spectroscopy (LC-MS/MS) were used to analyze grab samples of surface waters collected from five different watersheds in Barbados, West Indies...
November 14, 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29132732/the-role-of-artificial-and-natural-sweeteners-in-reducing-the-consumption-of-table-sugar-a-narrative-review
#3
REVIEW
Arshag D Mooradian, Meridith Smith, Masaaki Tokuda
The rapid increase in the prevalence of obesity worldwide has been partially attributed to the overconsumption of added sugars. Recent guidelines call for limiting the consumption of simple sugars to less than 10% of daily caloric consumption. High intensity sweeteners are regulated as food additives and include aspartame, acesulfame-k, neotame, saccharin, sucralose, cyclamate and alitame. Steviol glycosides and Luo Han Guo fruit extracts are high intensity sweeteners that are designated as generally recognized as safe (GRAS)...
April 2017: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/29131973/investigation-of-the-photocatalytic-transformation-of-acesulfame-k-in-the-presence-of-different-tio2-based-materials
#4
M J López-Muňoz, A Daniele, M Zorzi, C Medana, P Calza
The photocatalytic transformation of acesulfame K - an artificial sweetener that has gained popularity over the last decades for being a calorie-free additive in food, beverages and several pharmaceutical products - was studied using three different photocatalysts, the benchmark TiO2-P25 and two other forms of synthetized titanium oxides named TiO2-SG1 and TiO2-SG2. The two latter materials were synthesized by a sol gel process in which the hydrolysis rate of titanium n-butoxide was controlled by the water formed in situ through an esterification reaction between ethanol and acetic acid...
November 4, 2017: Chemosphere
https://www.readbyqxmd.com/read/29127847/effect-of-sucralose-on-the-enzyme-kinetics-of-invertase-using-real-time-nmr-spectroscopy-and-progress-curve-analysis
#5
Cheenou Her, Jaideep Singh, V V Krishnan
Sucralose, a derivative of sucrose, is widely used in noncaloric artificial sweeteners (NAS). Contrary to the belief that sucralose is physiologically inert and a healthy alternative sweetener to natural sugar, emerging studies indicate that sucralose alters the host metabolism as well as the composition of the microbiome. In this manuscript, we use real-time nuclear magnetic resonance (NMR) spectroscopy to demonstrate that sucralose alters the enzymatic conversion of sucrose to glucose and fructose. The real-time NMR progress curve analysis suggests that sucralose has the characteristic of a competitive inhibitor on the kinetics of the enzymatic process...
October 31, 2017: Carbohydrate Research
https://www.readbyqxmd.com/read/29127476/co-supplementation-of-isomalto-oligosaccharides-potentiates-metabolic-health-benefits-of-polyphenol-rich-cranberry-extract-in-high-fat-diet-fed-mice-via-enhanced-gut-butyrate-production
#6
Dhirendra Pratap Singh, Shashank Singh, Vandana Bijalwan, Vijay Kumar, Pragyanshu Khare, Ritesh Kumar Baboota, Paramdeep Singh, Ravneet Kaur Boparai, Jagdeep Singh, Kanthi Kiran Kondepudi, Kanwaljit Chopra, Mahendra Bishnoi
PURPOSE: Cranberries are a rich source of polyphenolic antioxidants. Purified sugars or artificial sweeteners are being added to cranberry-based food products to mask tartness. Refined sugar and artificial sweeteners intake modulate gut microbiota and result in metabolic complications. We evaluated effects of isomalto-oligosaccharides (IMOs; sweet tasting non-digestible oligosaccharides) with cranberry extract (CRX) on high fat diet (HFD)-induced metabolic alterations in mice. METHODS: Male Swiss albino mice were fed normal chow or HFD (58% fat kcal), and were administered either CRX (200 mg/kg) alone or in combination with IMOs (1 g/kg)...
November 10, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/29126998/high-runner-mice-have-reduced-incentive-salience-for-a-sweet-taste-reward-when-housed-with-wheel-access
#7
Zoe Thompson, Erik M Kolb, Theodore Garland
To explore reward substitution in the context of voluntary exercise, female mice from four replicate high-runner (HR) lines (bred for wheel running) and four non-selected control (C) lines were given simultaneous access to wheels and palatable solutions as competing rewards (two doses of saccharin [0.1, 0.2% w/v]; two doses of common artificial sweetener blends containing saccharin [Sweet 'N Low(®): 0.1, 0.2% w/v], aspartame [Equal(®): 0.04, 0.08% w/v], or sucralose [Splenda(®): 0.08, 0.16% w/v]; or two doses of sucrose [3...
November 7, 2017: Behavioural Processes
https://www.readbyqxmd.com/read/29124015/the-influence-of-parental-food-preference-and-neophobia-on-children-with-phenylketonuria-pku
#8
Sharon Evans, Anne Daly, Satnam Chahal, Catherine Ashmore, John MacDonald, Anita MacDonald
Background: In a previous case-control study, we demonstrated that children with PKU and non-PKU controls preferred sweet foods. Additionally, children with PKU exhibited food neophobia, with no preference for bitter tasting foods associated with the taste of phenylalanine (Phe)-free L-amino acid supplements. Objective: In an observational extension study, we evaluated the influence of parental food choice and neophobia on their children's taste preferences and food neophobia...
March 2018: Molecular Genetics and Metabolism Reports
https://www.readbyqxmd.com/read/29111886/predictive-modelling-of-the-exposure-to-steviol-glycosides-in-irish-patients-aged-1-3-years-with-phenylketonuria-and-cow-s-milk-protein-allergy
#9
Aaron J O'Sullivan, Sandrine Pigat, Cian O'Mahony, Michael J Gibney, Aideen I McKevitt
Children with Phenylketonuria (PKU) and severe cow's milk protein allergy (CMPA) consume prescribed, specially formulated, foods for special medical purposes (FSMPs) as well as restricted amounts of normal foods. These patients are exposed to artificial sweeteners from the consumption of a combination of free and prescribed foods. Young patients with PKU and CMPA have a higher risk of exceeding acceptable daily intakes (ADI) for additives than age-matched healthy children. A predictive modelling approach has been adapted successfully to assess the additive exposure of young patients with PKU and CMPA to artificial sweeteners...
November 7, 2017: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/29089128/pharmaceuticals-and-personal-care-products-ppcps-and-artificial-sweeteners-ass-in-surface-and-ground-waters-and-their-application-as-indication-of-wastewater-contamination
#10
Yuan-Yuan Yang, Jian-Liang Zhao, You-Sheng Liu, Wang-Rong Liu, Qian-Qian Zhang, Li Yao, Li-Xin Hu, Jin-Na Zhang, Yu-Xia Jiang, Guang-Guo Ying
We systematically investigated the occurrence and distribution of 93 pharmaceuticals and personal care products (PPCPs) and 5 artificial sweeteners (ASs) in surface water and groundwater of Dongjiang River basin in south China. In surface water, 52 compounds were detected with median concentrations ranging from 0.06ng/L to 504ng/L, while in groundwater, 33 compounds were detected with concentrations up to 4580ng/L for acesulfame. PPCPs and ASs were widely detected in the surface water and groundwater samples, which indicated contamination by domestic wastewater in the surface water and groundwater of Dongjiang River basin...
October 28, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29038387/nephrotoxic-effect-of-aspartame-as-an-artificial-sweetener-a-brief-review
#11
Mohammad Reza Ardalan, Hadi Tabibi, Vahideh Ebrahimzadeh Attari, Aida Malek Mahdavi
Aspartame is one of the most popular artificial sweeteners over the world. Although its consumption is considered to be safe in acceptable daily intake ranges which were set by the United States Food and Drugs Administration and other regulatory agencies, there are lots of controversies regarding its safety nowadays. Some of the recent experimental and epidemiological studies showed that consumption of aspartame may causes some adverse health effects including obesity, metabolic syndrome, and alteration in gut microbiota...
October 2017: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29025103/commentary-intrauterine-exposure-to-artificially-sweetened-beverages-and-offspring-adiposity-is-this-the-tip-of-the-iceberg
#12
Louise L Hardy
No abstract text is available yet for this article.
October 1, 2017: International Journal of Epidemiology
https://www.readbyqxmd.com/read/28987582/rheological-and-sensory-performance-of-a-protein-based-sweetener-mnei-sucrose-and-aspartame-in-yogurt
#13
Nicoletta A Miele, Erliza K Cabisidan, Giuseppe Blaiotta, Serena Leone, Paolo Masi, Rossella Di Monaco, Silvana Cavella
Sweeteners and flavors are generally added to yogurt to make them more palatable. However, the addition of these ingredients may affect the fermentation process of yogurt as well as its physical and sensory characteristics. Consumers prioritize yogurt products that are "natural." A modified single-chain form of the natural sweet protein monellin extracted from the fruit of Dioscoreophyllum cumminsii, called MNEI, could be a useful alternative to artificial sweeteners. The aim of the present work was to evaluate new rapid sensory methods in combination with rheology to assess the viability of using MNEI to develop sweetened yogurts without the calories of sugar...
October 4, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28987500/evaluating-suspension-formulations-of-theophylline-cocrystals-with-artificial-sweeteners
#14
Srinivasulu Aitipamula, Annie B H Wong, Parijat Kanaujia
Pharmaceutical cocrystals have garnered significant interest as potential solids to address issues associated with formulation development of drug substances. However, studies concerning the understanding of formulation behavior of cocrystals are still at the nascent stage. We present results of our attempts to evaluate suspension formulations of cocrystals of an antiasthmatic drug, theophylline, with 2 artificial sweeteners. Stability, solubility, drug release, and taste of the suspension formulations were evaluated...
October 5, 2017: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28973043/correction-acute-effects-of-sugars-and-artificial-sweeteners-on-small-intestinal-sugar-transport-a-study-using-caco-2-cells-as-an-in-vitro-model-of-the-human-enterocyte
#15
Patrick O'Brien, Christopher Peter Corpe
[This corrects the article DOI: 10.1371/journal.pone.0167785.].
2017: PloS One
https://www.readbyqxmd.com/read/28971978/activation-of-the-sweet-taste-receptor-t1r3-by-the-artificial-sweetener-sucralose-regulates-the-pulmonary-endothelium
#16
Elizabeth O Harrington, Alexander Vang, Julie Braza, Aparna Shil, Havovi Chichger
A hallmark of acute respiratory distress syndrome (ARDS) is pulmonary vascular permeability. In these settings, loss of barrier integrity is mediated by cell-contact disassembly and actin-remodelling. Studies into molecular mechanisms responsible for improving microvascular barrier function are therefore vital in the development of therapeutic targets for reducing vascular permeability in ARDS. The sweet taste receptor, T1R3 is a GPCR, activated following exposure to sweet molecules, to trigger a gustducin-dependent signal cascade...
September 28, 2017: American Journal of Physiology. Lung Cellular and Molecular Physiology
https://www.readbyqxmd.com/read/28968411/the-effect-of-sucralose-on-flavor-sweetness-in-electronic-cigarettes-varies-between-delivery-devices
#17
Kathryn Rosbrook, Hanno C Erythropel, Tamara M DeWinter, Mark Falinski, Stephanie O'Malley, Suchitra Krishnan-Sarin, Paul T Anastas, Julie B Zimmerman, Barry G Green
The appeal of sweet electronic cigarette flavors makes it important to identify the chemical compounds that contribute to their sweetness. While volatile chemicals that produce sweet aromas have been identified in e-liquids, there are no published reports of sugars or artificial sweeteners in commercial e-liquids. However, the sweetener sucralose is marketed as an e-liquid additive to commercial flavors. The primary aims of the study were to determine if sucralose is delivered in sufficient concentration in the inhaled aerosol to enhance flavor sweetness, and whether the amount delivered depends on the e-liquid delivery system...
2017: PloS One
https://www.readbyqxmd.com/read/28957917/newscap-artificial-sweeteners-do-not-improve-health-and-may-even-be-detrimental
#18
(no author information available yet)
No abstract text is available yet for this article.
October 2017: American Journal of Nursing
https://www.readbyqxmd.com/read/28938797/revisiting-the-safety-of-aspartame
#19
Arbind Kumar Choudhary, Etheresia Pretorius
Aspartame is a synthetic dipeptide artificial sweetener, frequently used in foods, medications, and beverages, notably carbonated and powdered soft drinks. Since 1981, when aspartame was first approved by the US Food and Drug Administration, researchers have debated both its recommended safe dosage (40 mg/kg/d) and its general safety to organ systems. This review examines papers published between 2000 and 2016 on both the safe dosage and higher-than-recommended dosages and presents a concise synthesis of current trends...
September 1, 2017: Nutrition Reviews
https://www.readbyqxmd.com/read/28886707/health-outcomes-of-non-nutritive-sweeteners-analysis-of-the-research-landscape
#20
REVIEW
Szimonetta Lohner, Ingrid Toews, Joerg J Meerpohl
BACKGROUND: Food products containing non-nutritive sweeteners (NNSs) instead of sugar have become increasingly popular in the last decades. Their appeal is obviously related to their calorie-free sweet taste. However, with the dramatic increase in their consumption, it is reasonable and timely to evaluate their potential health benefits and, more importantly, potential adverse effects. The main aim of this scoping review was to map the evidence about health outcomes possibly associated with regular NNS consumption by examining the extent, range, and nature of research activity in this area...
September 8, 2017: Nutrition Journal
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