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Vit D

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https://www.readbyqxmd.com/read/27903510/vitamin-d-supplementation-reduces-some-at1-aa-induced-downstream-targets-implicated-in-preeclampsia-including-hypertension
#1
Jessica L Faulkner, Lorena M Amaral, Denise C Cornelius, Mark W Cunningham, Tarek Ibrahim, Autumn Heep, Nathan Campbell, Nathan Usry, Kedra Wallace, Florian Herse, Ralf Dechend, Babbette D LaMarca
Autoantibodies to the angiotensin II (ANGII) type I receptor (AT1-AA) are associated with preeclampsia (PE). We found that Vitamin D supplementation reduced AT1-AA and blood pressure (MAP) in the RUPP rat model of PE. However, it was undetermined if the decrease in AT1-AA was the mechanism whereby Vitamin D lowered MAP or if it was through factors downstream of AT1-AA. Uterine artery resistance index, placental ET-1 and sFlt-1 are increased with AT1-AA induced hypertension and considered markers of PE in pregnant women...
November 30, 2016: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/27863277/vitamin-d-supplementation-affects-the-igf-system-in-men-after-acute-exercise
#2
Rachel L Darr, Kathleen J Savage, Mark Baker, Gregory E Wilding, Amy Raswalsky, Todd Rideout, Richard W Browne, Peter J Horvath
OBJECTIVE: Contradictory data between the Insulin-Like Growth Factor System (IGF) system and exercise may be due to alteration in IGF binding proteins. Vitamin D (D) deficiency has been related to muscle weakness and Insulin Like Growth Factor Binding Protein 3 (IGFBP3). A Vit. D and acute exercise merge is proposed to modify the IGF system. DESIGN: D insufficient and deficient men (39.0±8.6yo with serum D (25OH D) 20.0±7.7ng/mL) did 1h of stretching (ST), aerobic (AB), and resistance (RT) exercises, before and after 28d of 4000IU/d Vit...
November 5, 2016: Growth Hormone & IGF Research
https://www.readbyqxmd.com/read/27847277/influence-of-surfactants-on-depsipeptide-submicron-particle-formation
#3
Nadia Brunacci, Christian Wischke, Toufik Naolou, Axel T Neffe, Andreas Lendlein
Surfactants are required for the formation and stabilization of hydrophobic polymeric particles in aqueous environment. In order to form submicron particles of varying sizes from oligo[3-(S)-sec-butylmorpholine-2,5-dione]diols ((OBMD)-diol), different surfactants were investigated. As new surfactants, four-armed star-shaped oligo(ethylene glycol)s of molecular weights of 5-20kDa functionalized with desamino-tyrosine (sOEG-DAT) resulted in smaller particles with lower PDI than with desaminotyrosyl tyrosine (sOEG-DATT) in an emulsion/solvent evaporation method...
November 12, 2016: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/27846770/the-relationship-between-balance-and-vitamin-25-oh-d-in-fibromyalgia-patients
#4
Meliha Kasapoğlu Aksoy, Lale Altan, Burcu Ökmen Metin
: INTRODUCTİON: Fibromyalgia syndrome (FMS) is a chronic disease characterized by diffuse pain of unknown cause, fatigue, sleep disorders, cognitive dysfunction and sensitivity. Fibromyalgia was shown to be associated with balance problems and increased incidence of falls. There are many theoretical mechanisms related to the impact of vitamin D on postural control. The aim of the current study was to investigate the relationship between vitamin 25(OH)D levels and pain, balance and daily activities in patients with FMS...
November 16, 2016: Modern Rheumatology
https://www.readbyqxmd.com/read/27769784/vitamin-d3-supplementation-among-adult-patients-with-cystic-fibrosis
#5
Adèle Coriati, Évelyne Labrèche, Marjolaine Mailhot, Hortensia Mircescu, Yves Berthiaume, Annick Lavoie, Rémi Rabasa-Lhoret
BACKGROUND & AIMS: Vitamin D (Vit D) deficiency in cystic fibrosis (CF) is partially secondary to exocrine pancreatic insufficiency. Our aim was to establish a Vit D3 supplementation protocol that will increase 25(OH)D to the recommended level (30 ng/mL). METHODS: Retrospective study of 200 patients (≥18 years) conducted from February 2007 to June 2014 at the CF clinic of the Centre Hospitalier de l'Université de Montréal. Vit D3 supplementation protocol was 1600 IU/day or 10,000 IU/week during the summer (May 1st to October 31st) and 3200 IU/day or 20,000 IU/week during the winter (November 1st to April 30th), in addition to the 1200 IU/day included in multivitamins...
October 8, 2016: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/27729974/acetylsalicylic-acid-supplementation-improves-protein-utilization-efficiency-while-vitamin-e-supplementation-reduces-markers-of-the-inflammatory-response-in-weaned-pigs-challenged-with-enterotoxigenic-e-coli
#6
Jae Cheol Kim, Bruce P Mullan, John L Black, Robert J E Hewitt, Robert J van Barneveld, John R Pluske
BACKGROUND: This experiment was conducted to test the hypothesis that vitamin E (Vit E) and acetylsalicylic acid (ASA), a cyclooxygenase-2 (COX-2) inhibitor, will additively reduce the production of the immunosuppressive molecule prostaglandin E2 (PGE2) and hence reduce inflammatory responses in weaner pigs experimentally infected with an enterotoxigenic strain of E. coli. METHODS: The experiment was conducted in a research facility with 192 individually-housed male weaner pigs (Landrace × Large White) weighing 6...
2016: Journal of Animal Science and Biotechnology
https://www.readbyqxmd.com/read/27728007/study-of-association-of-vit-d-deficiency-and-hypertension
#7
Shalini Priya, Abhishek Singh, Sanjay Mehrotra, A Pradhan
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27720520/three-dimensional-ultrasound-guided-real-time-midline-epidural-needle-placement-with-epiguide-a-prospective-feasibility-study
#8
Parmida Beigi, Paul Malenfant, Abtin Rasoulian, Robert Rohling, Alison Dube, Vit Gunka
Current 2-D ultrasound technology is unable to perform a midline neuraxial needle insertion under real-time ultrasound guidance using a standard needle and without an assistant. The aim of the work described here was to determine the feasibility of a new technology providing such capability, starting with a study evaluating the selected puncture site. A novel 3-D ultrasound imaging technique was designed using thick-slice rendering in conjunction with a custom needle guide (3DUS + Epiguide). A clinical feasibility study evaluated the ability of 3DUS + Epiguide to identify the epidural needle puncture site for a midline insertion in the lumbar spine...
October 6, 2016: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/27713770/the-role-of-vitamin-d-in-immuno-inflammatory-responses-in-ankylosing-spondylitis-patients-with-and-without-acute-anterior-uveitis
#9
T C Mitulescu, C Stavaru, L M Voinea, L M Banica, C Matache, D Predeteanu
Hypothesis:Abnormal Vitamin D (Vit D) level could have consequences on the immuno-inflammatory processes in Ankylosing Spondylitis (AS). Aim:The purpose of this study was to analyze the role of Vitamin D in the interplay between immune and inflammation effectors in AS associated-Acute Anterior Uveitis (AAU). Methods and Results:25-hydroxyvitamin D (Vit D), LL-37 peptide, IL-8 and Serum Amyloid A (SAA) were identified and quantified in the serum/ plasma of thirty-four AS patients [eleven AS patients presenting AAU (AAU AS patients) and twenty-three AS patients without AAU (wAAU AS patients)] and eighteen healthy individuals (Control) using enzyme-linked immunosorbent assay...
January 2016: Journal of Medicine and Life
https://www.readbyqxmd.com/read/27650228/vitamin-d-supplementation-not-so-simple-in-sarcoidosis
#10
Amik Sodhi, Thomas Aldrich
INTRODUCTION: Americans are increasingly receiving vitamin D supplementation, often based on low-measured 25-hydroxy-vitamin D (25-OH-vit D). In sarcoidosis, there is often increased metabolism of 25-OH-vit D to 1,25-dihydroxy-vitamin D (1,25-OH-vit D), so 25-OH-vit D may remain low, despite high levels of 1,25-OH-vit D. In such cases, vitamin D supplementation may lead to hypercalcemia. METHODS: We randomly selected 196 patients with sarcoidosis who received at least 1 prescription of vitamin D between 2005 and 2011 and 196 control patients...
September 2016: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/27616756/vitamin-d-levels-vitamin-d-supplementation-and-prognosis-in-patients-with-chronic-kidney-disease%C3%A2
#11
Yossef Namir, Matan J Cohen, Yosef S Haviv, Itzchak Slotki, Linda Shavit
BACKGROUND: Vitamin D (Vit D) deficiency plays a central role in the pathogenesis of chronic kidney disease (CKD) complications, both skeletal and nonskeletal. The purpose of this study was to examine whether 25(OH)D levels and supplementation with oral cholecalciferol (Vitamin D3 (Vit D3)) are associated with morbidity and mortality among patients with significant CKD. METHODS: CKD patients attending the nephrology clinic at Shaare Zedek Medical Center between July 1, 2008 and January 31, 2012, tested at least twice for 25(OH)D levels, were enrolled...
October 2016: Clinical Nephrology
https://www.readbyqxmd.com/read/27605743/current-scenario-of-prevalence-of-vitamin-d-deficiency-in-ostensibly-healthy-indian-population-a-hospital-based-retrospective-study
#12
Kirtikar Shukla, Shikha Sharma, Aditi Gupta, Arun Raizada, Kamini Vinayak
25-hydroxy vitamin D [25(OH) vit D] deficiency is a serious public health problem, particularly in the Indian sub-continent. The objective of the present study was to study the prevalence of 25(OH) vit D in different age groups. The data of 25(OH) vit D assay of 26,346 ostensibly healthy individuals, enrolled under executive health checkup at Medanta The Medicity, Gurgaon, over a period of 3 years, were extracted from the hospital information system and reviewed extensively. 25(OH) vit D deficiency (VDD) was defined as 25(OH) vit D < 20 ng/ml, insufficiency (VDI) as 25(OH) vit D between 20 and 40 ng/ml and 25(OH) vit D sufficiency (VDS) as 25(OH) D > 40 ng/mL...
October 2016: Indian Journal of Clinical Biochemistry: IJCB
https://www.readbyqxmd.com/read/27574411/plasma-homocysteine-level-is-a-risk-factor-for-osteoporotic-fractures-in-elderly-patients
#13
Yuefeng Zhu, Jie Shen, Qun Cheng, Yongqian Fan, Weilong Lin
OBJECTIVE: To study the relationship of plasma homocysteine (Hcy), bone turnover biomarkers (BTB), and bone mineral density (BMD) with osteoporotic fracture (OPF) in elderly people. METHODS: Eighty-two patients (aged 65 years or older) admitted to our orthopedics department between October 2014 and May 2015 were randomly divided into three groups: 1) OPF group: 39 cases with the mean age 81.82±5.49 years, which included 24 females and 15 males; 2) high-energy fracture (HEF) group: 22 cases with the mean age 78...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27560913/-influence-of-serum-levels-of-vitamin-d-on-ige-response-in-schoolchildren-with-asthma-in-poor-communities
#14
Eduardo Egea, Gloria Garavito, Luis Fang, Dary Luz Mendoza, José Miguel Escamilla, Elsie De Los Ríos, Rodolfo Dennis, Mario Sánchez-Borges
BACKGROUND: Asthma is a common disease in the world and vitamin D (Vit-D) has been associated with the presence and severity of this disease. OBJECTIVE: To establish the association between levels of Vit-D and IgE response in schoolchildren with asthma living in four cities in Colombia. METHODS: Case-control study in 1340 schoolchildren (687 asthmatic and 653 controls) from communities in extreme poverty in Barranquilla, Cartagena, Santa Marta, and Montería...
July 2016: Revista Alergia Mexico: Organo Oficial de la Sociedad Mexicana de Alergia e Inmunología, A.C
https://www.readbyqxmd.com/read/27476528/prevalence-of-vitamin-d-deficiency-and-calcium-homeostasis-in-saudi-children-and-adolescents
#15
Adnan M Al Shaikh, Bahaa Abaalkhail, Ashraf Soliman, Ibrahim Kaddam, Khalid Aseri, Yousef Al Saleh, Ali Al Qarni, Ahmed Al Shuaibi, Waleed Al Tamimi, Abdel Moniem Mukhtar
OBJECTIVE: Vitamin D deficiency (VDD) and insufficiency (VDI) are significant health problem all-over the world. The aim of this study was to determine the prevalence of VDD and VDI in children and adolescents residing in 8 provinces in the Kingdom of Saudi Arabia (KSA) and to investigate their calcium homeostasis. METHODS: A cross-sectional study with 2110 participants aged between 6 and 15 years were enrolled. The questionnaire included personal and socio-demographic, anthropometric measurements, knowledge about vitamin D, color of the skin, dietary intake, sun exposure experience, smoking, and physical activity...
July 30, 2016: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/27468766/vitamin-d-receptor-vdr-gene-polymorphisms-taqi-foki-in-turkish-patients-with-hashimoto-s-thyroiditis-relationship-to-the-levels-of-vit-d-and-cytokines
#16
Bedia Guleryuz, Fulya Akin, Melek T Ata, Mukaddes Mergen Dalyanoglu, Sebahat Turgut
BACKGROUND: Hashimoto's thyroiditis (HT) is a common autoimmune disease. Vitamin D is an important regulator of immune system. It has been shown in several studies that vitamin D prevents the development of lots of autoimmune diseases. There are some studies that prove vitamin D receptor (VDR) gene polymorphism increases the risk of Hashimoto's thyroiditis. In this study, we aimed to investigate the association between HT and level of 25(OH)D3, IL-2, IL-4, IL-5, TNF-α and IFN-γ and VDR FokI and TaqI gene polymorphism...
July 27, 2016: Endocrine, Metabolic & Immune Disorders Drug Targets
https://www.readbyqxmd.com/read/27430982/proteomic-analysis-of-imatinib-resistant-cml-t1-cells-reveals-calcium-homeostasis-as-a-potential-therapeutic-target
#17
O Toman, T Kabickova, O Vit, R Fiser, K Machova Polakova, J Zach, J Linhartova, D Vyoral, J Petrak
Chronic myeloid leukemia (CML) therapy has markedly improved patient prognosis after introduction of imatinib mesylate for clinical use. However, a subset of patients develops resistance to imatinib and other tyrosine kinase inhibitors (TKIs), mainly due to point mutations in the region encoding the kinase domain of the fused BCR-ABL oncogene. To identify potential therapeutic targets in imatinib‑resistant CML cells, we derived imatinib-resistant CML-T1 human cell line clone (CML-T1/IR) by prolonged exposure to imatinib in growth media...
September 2016: Oncology Reports
https://www.readbyqxmd.com/read/27416038/how-is-the-relation-between-endocrine-changes-and-bone-markers-in-pediatric-thalassemic-patients-after-hematopoietic-stem-cell-transplantation
#18
Amir A Hamidieh, Zohreh Hamidi, Maryam Behfar, Zeinab Pajouhi, Kamran Alimoghaddam, Fariba Mohseni, Ardeshir Ghavamzadeh, Maryam Sobhani, Bagher Larijani, Mohammad R Mohajeri Tehrani
BACKGROUNDS: Beta Thalassemia Major, and its treatment by hematopoietic stem cell transplantation can have deleterious effect on bone integrity and a main part of such effects is due to their deleterious effects on endocrine systems. So, we assessed the effects of endocrine changes during HSCT (Hematopoietic Stem Cell Transplantation) on growing bones of pediatric thalassemic patients. METHODS: Bone-specific alkaline phosphatase and osteocalcin (bone formation markers), NTX (bone resorption marker), Ca, P, Alk ph, PTH, Vitamin D (vit D), prolactin, LH, FSH, T4, T3, TSH, IGF-1, testosterone (in males) or estradiol (in females), measured in 20 major thalassemic patients with mean age of 10...
July 14, 2016: Minerva Pediatrica
https://www.readbyqxmd.com/read/27374925/analysis-of-the-safety-and-tolerance-of-three-buildup-protocols-of-insect-venom-immunotherapy-frequently-used-in-spain
#19
D Gutiérrez Fernández, A Moreno-Ancillo, S Fernández Meléndez, C Domínguez-Noche, P Gálvez Ruiz, T Alfaya Arias
INTRODUCTION: Hymenoptera venom immunotherapy (VIT) is an effective treatment but not one devoid of risk as both local and systemic adverse reactions may occur especially in the initial stages of treatment. We compared the tolerance to three buildup protocols of VIT and analyzed risk factors associated with adverse reactions occurring in this phase. METHODS: We enrolled 165 patients divided into three groups based on the buildup protocol used (3, 4, 9 weeks). Severity of systemic reactions was evaluated according to World Allergy Organization model...
April 19, 2016: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/27278776/erosive-potential-of-vitamin-and-vitamin-mineral-effervescent-tablets
#20
COMPARATIVE STUDY
Florian J Wegehaupt, Nancy Lunghi, Vanessa M G Hogger, Thomas Attin
The extrinsic sources for erosion-causing acids are primarily acidic beverages and foodstuffs. Effervescent tablets also contain organic acids (e.g. citric, tartaric, malic) in order to form carbon dioxide by contact with water – with the help of the carbonate salts of the tablets. To adequately inform patients about the possible erosive potential of effervescent tablets, this study was undertaken in order to investigate the erosive potential of effervescent tablets (ET), containing either a combination of vitamins and minerals or vitamins only, commercially available in Switzerland...
2016: Swiss Dental Journal
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