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https://www.readbyqxmd.com/read/27924348/photoacoustic-guided-focused-ultrasound-for-accurate-visualization-of-brachytherapy-seeds-with-the-photoacoustic-needle
#1
Mithun Kuniyil Ajith Singh, Vinay Parameshwarappa, Ellen Hendriksen, Wiendelt Steenbergen, Srirang Manohar
No abstract text is available yet for this article.
December 1, 2016: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/27924157/biodegradable-nitrogen-doped-carbon-nanodots-for-non-invasive-photoacoustic-imaging-and-photothermal-therapy
#2
Changho Lee, Woosung Kwon, Songeun Beack, Donghyun Lee, Yoonsang Park, Hyemin Kim, Sei Kwang Hahn, Shi-Woo Rhee, Chulhong Kim
Multifunctional nanoparticles have been widely investigated for biomedical applications, such as imaging, therapy, and drug delivery. Especially, photoactive nanoparticles have received great attention as theranostic agents because of their heat-generating abilities after exposure to laser irradiation. However, photostability and safety issues have been the technical hurdles for further clinical applications. Here, we designed nitrogen (N)-doped carbon nanodots (N-CNDs) that have strong absorption in the near-infrared region, high photostability, and excellent biodegradability...
2016: Theranostics
https://www.readbyqxmd.com/read/27924155/versatile-ph-response-micelles-with-high-cell-penetrating-helical-diblock-copolymers-for-photoacoustic-imaging-guided-synergistic-chemo-photothermal-therapy
#3
Shengyu Shi, Yajing Liu, Yu Chen, Zhihuang Zhang, Yunsheng Ding, Zongquan Wu, Jun Yin, Liming Nie
With high optical absorption efficiency, near infrared (NIR) dyes have been proposed as theranostic agents for fluorescence imaging, photoacoustic imaging (PAI), and photothermal therapy (PTT). However, inherent hydrophobicity and short circulation time of small molecule hinder the further biomedical application. Herein smart amphiphilic copolymer was synthesized containing IR780/camptothecin@poly(ε-caprolactone) (IR780/CPT@PCL) as core, helical poly(phenyl isocyanide) (PPI) blocks as shell with the pH-responsive rhodamine B (RhB) moieties in the core-shell interface...
2016: Theranostics
https://www.readbyqxmd.com/read/27921316/light-triggered-assembly-of-gold-nanoparticles-for-photothermal-therapy-and-photoacoustic-imaging-of-tumors-in-vivo
#4
Xiaju Cheng, Rui Sun, Ling Yin, Zhifang Chai, Haibin Shi, Mingyuan Gao
Photocross-linkable Au nanoparticles are prepared through surface decoration of photolabile diazirine moieties. Both in vitro and in vivo studies indicate that the light-triggered cross-linking can dramatically shift the surface plasmon resonance of Au nanoparticles to near-infrared regions, which in consequence remarkably enhances their efficacy for photothermal therapy and photoacoustic imaging of tumors in vivo.
December 6, 2016: Advanced Materials
https://www.readbyqxmd.com/read/27921170/effect-of-photon-initiated-photoacoustic-streaming-passive-ultrasonic-and-sonic-irrigation-techniques-on-dentinal-tubule-penetration-of-irrigation-solution-a-confocal-microscopic-study
#5
Merve Akcay, Hakan Arslan, Merve Mese, Nazlı Durmus, Ismail Davut Capar
OBJECTIVES: The aim of this in vitro study was to evaluate the efficacy of different irrigation techniques including laser-activated irrigation using an erbium:yttrium-aluminum-garnet (Er:YAG) laser with a novel tip design (photon-induced photoacoustic streaming (PIPS)), Er:YAG laser with Preciso tip, sonic activation, and passive ultrasonic activation on the final irrigation solution penetration into dentinal tubules by using a laser scanning confocal microscope. MATERIAL AND METHODS: In this study, 65 extracted single-rooted human mandibular premolars were instrumented up to size 40 and randomly divided into 5 groups (n = 13) based on the activation technique of the final irrigation solution as follows: conventional irrigation (control group), sonic activation, passive ultrasonic activation, Er:YAG-PIPS tip activation, and Er:YAG-Preciso tip activation...
December 5, 2016: Clinical Oral Investigations
https://www.readbyqxmd.com/read/27918801/quantitative-photoacoustic-tomography-using-forward-and-adjoint-monte-carlo-models-of-radiance
#6
Roman Hochuli, Samuel Powell, Simon Arridge, Ben Cox
No abstract text is available yet for this article.
December 1, 2016: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/27918790/near-infrared-light-responsive-liposomal-contrast-agent-for-photoacoustic-imaging-and-drug-release-applications
#7
Kathyayini Sivasubramanian, Malathi Mathiyazhakan, Christian Wiraja, Paul Kumar Upputuri, Chenjie Xu, Manojit Pramanik
No abstract text is available yet for this article.
April 1, 2017: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/27914443/converting-sunlight-into-audible-sound-by-means-of-the-photoacoustic-effect-the-heliophone
#8
N B Roozen, C Glorieux, L Liu, M Rychtáriková, T Van der Donck, A Jacobs
One hundred and thirty-five years after Alexander Graham Bell and his assistant Charles Sumner Tainter explored the photoacoustic effect, and about 40 years after Rosencwaig and Gersho modeled the effect in a photoacoustic cell configuration, the phenomenon is revisited in a "Heliophone" device that converts sunlight into sound. The light is focused on a carbon blackened copper coated Kapton foil in an acoustic cell by means of a compound parabolic collimator, and its intensity is modulated by a mechanical chopper...
September 2016: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/27911452/rationally-encapsulated-gold-nanorods-improving-both-linear-and-nonlinear-photoacoustic-imaging-contrast-in-vivo
#9
Fei Gao, Linyi Bai, Siyu Liu, Ruochong Zhang, Jingtao Zhang, Xiaohua Feng, Yuanjin Zheng, Yanli Zhao
Photoacoustic tomography has emerged as a promising non-invasive imaging technique that integrates the merits of high optical contrast with high ultrasound resolution in deep scattering medium. Unfortunately, the blood background in vivo seriously impedes the quality of imaging due to its comparable optical absorption with contrast agents, especially in conventional linear photoacoustic imaging modality. In this study, we demonstrated that two hybrids consisting of gold nanorods (Au NRs) and zinc tetra(4-pyridyl)porphyrin (ZnTPP) exhibited a synergetic effect in improving optical absorption, conversion efficiency from light to heat, and thermoelastic expansion, leading to a notable enhancement in both linear (four times greater) and nonlinear (more than six times) photoacoustic signals as compared with conventional Au NRs...
December 2, 2016: Nanoscale
https://www.readbyqxmd.com/read/27910824/accelerated-high-resolution-photoacoustic-tomography-via-compressed-sensing
#10
Simon Arridge, Paul Beard, Marta Betcke, Ben Cox, Nam Huynh, Felix Lucka, Olumide Ogunlade, Edward Zhang
Current 3D photoacoustic tomography (PAT) systems offer either high image quality or high frame rates but are not able to deliver high spatial and temporal resolution simultaneously, which limits their ability to image dynamic processes in living tissue (4D PAT). A particular example is the planar Fabry-Pérot (FP) photoacoustic scanner, which yields high-resolution 3D images but takes several minutes to sequentially map the incident photoacoustic field on the 2D sensor plane, point-by-point. However, as the spatio-temporal complexity of many absorbing tissue structures is rather low, the data recorded in such a conventional, regularly sampled fashion is often highly redundant...
December 21, 2016: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/27908189/thermoacoustic-imaging-of-rabbit-knee-joints
#11
Zihui Chi, Yuan Zhao, Lin Huang, Zhu Zheng, Huabei Jiang
PURPOSE: Knee joint is one of the largest and most complex joints of the body. Knee joint diseases are common, and current clinical imaging technologies such as x-ray computed tomography, magnetic resonance imaging, and ultrasound imaging have limitations in the diagnosis of knee joint diseases. Emerging imaging technologies such as diffuse optical tomography and photoacoustic imaging (PAI) have been applied to the detection of osteoarthritis (OA). However, they are limited to small joints such as the finger and difficult to be used for large joints such as the knee...
December 2016: Medical Physics
https://www.readbyqxmd.com/read/27906478/activatable-photoacoustic-nanoprobes-for-in-vivo-ratiometric-imaging-of-peroxynitrite
#12
Jianjian Zhang, Xu Zhen, Paul Kumar Upputuri, Manojit Pramanik, Peng Chen, Kanyi Pu
Organic semiconducting nanoprobes doped with bulky borane can undergo specific activation by ONOO(-) even at tumor-relevant acidic pH (6.8), permitting in vivo ratiometric photoacoustic imaging of ONOO(-) in the tumor environment of living mice.
December 1, 2016: Advanced Materials
https://www.readbyqxmd.com/read/27906396/gadolinium-oxysulfide-coated-gold-nanorods-with-improved-stability-and-dual-modal-magnetic-resonance-photoacoustic-imaging-contrast-enhancement-for-cancer-theranostics
#13
Tao Guo, Yan Lin, Zhi Li, Shan Chen, Guoming Huang, Huirong Lin, Jun Wang, Gang Liu, Huang-Hao Yang
Gold nanorods (GNRs) are emerging as a promising nanoplatform for cancer theranostics because of their unique optical properties. However, they still suffer from many limitations, such as high cytotoxicity, low thermodynamic and biological stability, and a tedious process for integrating other imaging modalities, for further practical biomedical applications. In this work, a strategy by one-step coating of Gd2O2S around GNRs is reported to address these limitations of GNRs. After the coating of the Gd2O2S shell, the as-fabricated Gd2O2S coated GNRs (GNRs@Gd2O2S) show enhanced biocompatibility and photostability, and tunable localized surface plasmon resonance...
December 1, 2016: Nanoscale
https://www.readbyqxmd.com/read/27906377/lock-in-detection-of-photoacoustic-feedback-signal-for-focusing-through-scattering-media-using-wave-front-shaping
#14
Omer Tzang, Rafael Piestun
Wave-front shaping techniques enable focusing and imaging through scattering media. Unfortunately, most approaches require invasive feedback inside or behind the sample, or use of spatial correlations (memory effect) limiting the application to specific types of samples. Recent approaches overcome these limitations by taking advantage of acoustic waves via the photoacoustic (PA) effect or via photon tagging. We present a fully analog signal processing lock-in scheme for PA detection to improve focusing through scattering media and to efficiently extract nonlinear photoacoustic signals towards wave-front optimization...
November 28, 2016: Optics Express
https://www.readbyqxmd.com/read/27906261/impact-of-nonstationary-optical-illumination-on-image-reconstruction-in-optoacoustic-tomography
#15
Yang Lou, Kun Wang, Alexander A Oraevsky, Mark A Anastasio
Optoacoustic tomography (OAT), also known as photoacoustic tomography, is a rapidly emerging hybrid imaging technique that possesses great potential for a wide range of biomedical imaging applications. In OAT, a laser is employed to illuminate the tissue of interest and acoustic signals are produced via the photoacoustic effect. From these data, an estimate of the distribution of the absorbed optical energy density within the tissue is reconstructed, referred to as the object function. This quantity is defined, in part, by the distribution of light fluence within the tissue that is established by the laser source...
December 1, 2016: Journal of the Optical Society of America. A, Optics, Image Science, and Vision
https://www.readbyqxmd.com/read/27901548/microsphere-enabled-subdiffraction-limited-optical-resolution-photoacoustic-microscopy-a-simulation-study
#16
Paul Kumar Upputuri, Moganasundari Krisnan, Manojit Pramanik
No abstract text is available yet for this article.
April 1, 2017: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/27895986/combined-frequency-domain-photoacoustic-and-ultrasound-imaging-for-intravascular-applications
#17
Robin F Castelino, Michael Hynes, Chelsea E Munding, Sergey Telenkov, F Stuart Foster
Intravascular photoacoustic (IVPA) imaging has the potential to characterize lipid-rich structures based on the optical absorption contrast of tissues. In this study, we explore frequency domain photoacoustics (FDPA) for intravascular applications. The system employed an intensity-modulated continuous wave (CW) laser diode, delivering 1W over an intensity modulated chirp frequency of 4-12MHz. We demonstrated the feasibility of this approach on an agar vessel phantom with graphite and lipid targets, imaged using a planar acoustic transducer co-aligned with an optical fibre, allowing for the co-registration of IVUS and FDPA images...
November 1, 2016: Biomedical Optics Express
https://www.readbyqxmd.com/read/27893089/photoacoustic-mammography-capable-of-simultaneously-acquiring-photoacoustic-and-ultrasound-images
#18
Yasufumi Asao, Yohei Hashizume, Takahiro Suita, Ken-Ichi Nagae, Kazuhiko Fukutani, Yoshiaki Sudo, Toshikazu Matsushita, Shuichi Kobayashi, Mariko Tokiwa, Iku Yamaga, Elham Fakhrejahani, Masae Torii, Masahiro Kawashima, Masahiro Takada, Shotaro Kanao, Masako Kataoka, Tsuyoshi Shiina, Masakazu Toi
No abstract text is available yet for this article.
November 1, 2016: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/27893078/recent-advances-toward-preclinical-and-clinical-translation-of-photoacoustic-tomography-a-review
#19
Paul Kumar Upputuri, Manojit Pramanik
No abstract text is available yet for this article.
April 1, 2017: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/27881817/photoacoustic-imaging-sounds-the-alarm-on-liver-fibrosis
#20
Conor L Evans
No abstract text is available yet for this article.
November 23, 2016: Science Translational Medicine
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